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A Review and an Update on Pharmacological Treatment of Children With Attention-Deficit/Hyperactivity Disorder. 儿童注意缺陷/多动障碍的药物治疗综述与进展。
IF 0.8 Q4 PSYCHIATRY Pub Date : 2025-01-01 DOI: 10.5765/jkacap.240040
Taeyeop Lee, Hyo-Won Kim
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引用次数: 0
Association Between Endocrine-Disrupting Chemicals Exposure and Attention-Deficit/Hyperactivity Disorder Symptoms in Children With Attention-Deficit/Hyperactivity Disorder. 内分泌干扰物暴露与儿童注意缺陷/多动障碍症状的关系
IF 0.8 Q4 PSYCHIATRY Pub Date : 2025-01-01 DOI: 10.5765/jkacap.240035
Kang-Eun Yeo, Seungbee Lim, Aelin Kim, You Bin Lim, Chae Rim Lee, Johanna Inhyang Kim, Bung-Nyun Kim

Objectives: This study investigated the relationship between exposure to endocrine-disrupting chemicals (EDCs), specifically phthalates, bisphenol A, bisphenol F, and bisphenol S, and the severity of attention-deficit/hyperactivity disorder (ADHD) symptoms using neuropsychological tests in children diagnosed with ADHD.

Methods: This study included 67 medication-naïve children with ADHD aged 6-16 years. The urinary concentrations of EDCs were measured, and ADHD symptom severity was evaluated using neuropsychological tests and clinical symptom scale measurements. The Jonckheere-Terpstra test, Pearson and Spearman correlation analyses, linear regression models, and multiple regression models were used to examine the relationship between EDC exposure and ADHD symptoms.

Results: A significant correlation was observed between urinary phthalate metabolite concentrations and commission error T-scores in the visual Advanced Test of Attention test. No significant associations were found with other neuropsychological indicators or bisphenol levels.

Conclusion: Phthalate exposure affects impulsivity in children with ADHD, which is consistent with the results of previous studies that used parental surveys. However, bisphenols are not clearly associated with ADHD symptoms, which is consistent with the results of previous studies.

目的:本研究通过神经心理学测试,探讨暴露于内分泌干扰化学物质(EDCs),特别是邻苯二甲酸盐、双酚A、双酚F和双酚S与诊断为ADHD的儿童的注意力缺陷/多动障碍(ADHD)症状的严重程度之间的关系。方法:本研究纳入67例medication-naïve 6-16岁ADHD儿童。测量尿中EDCs浓度,并通过神经心理学测试和临床症状量表评估ADHD症状严重程度。采用Jonckheere-Terpstra检验、Pearson和Spearman相关分析、线性回归模型和多元回归模型检验EDC暴露与ADHD症状的关系。结果:尿邻苯二甲酸盐代谢物浓度与视觉注意力高级测验中的委托误差t分呈显著相关。没有发现与其他神经心理指标或双酚水平有显著关联。结论:邻苯二甲酸盐暴露会影响多动症儿童的冲动性,这与之前使用父母调查的研究结果一致。然而,双酚类物质与ADHD症状的关系并不明显,这与以往的研究结果一致。
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引用次数: 0
Emotional Abuse to Delinquent Tendencies: Comparative Study on Juveniles and Students in Punjab, Pakistan. 情绪虐待对犯罪倾向的影响:巴基斯坦旁遮普省青少年与学生的比较研究。
IF 0.8 Q4 PSYCHIATRY Pub Date : 2025-01-01 DOI: 10.5765/jkacap.240029
Nimrah Ishfaq, Anila Kamal

Objectives: This study aimed to explain the roles of physical and verbal aggression, emotional immaturity, and lying behavior in the predictive relationship between emotional abuse and delinquent tendencies among juveniles and students in Punjab, Pakistan.

Methods: Data were collected from 232 juveniles incarcerated in the Borstal Jails of Faisalabad and Bahawalpur. A comparative sample of 276 students from government schools was collected through purposive sampling. The comparative sample was matched for socioeconomic status, gender, location, and age. Translated (Urdu) versions of the standardized scales were used to measure the respective constructs. Path analysis was conducted to determine the mediating effects of lying (as a personality trait), emotional immaturity, and physical-verbal aggression on the relationship between emotional abuse and delinquent tendencies. Multigroup analysis was performed to determine the strength and significance of each path for juveniles and students.

Results: Emotional abuse positively predicted delinquent tendencies and emotional maturity, lying as a personality trait, and physical-verbal aggression mediated this relationship among juveniles and students. A decline in emotional maturity was a stronger predictor of delinquent tendencies among juveniles, whereas physical-verbal aggression played a stronger role for students.

Conclusion: This study demonstrates the indirect effects of emotional abuse on delinquent tendencies. This study also highlights the intense effect of emotional abuse on juvenile delinquents' emotional maturity and supports the importance of utilizing positive methods when dealing with adolescents, especially school personnel and clinical psychologists who interact with adolescents with problematic behaviors.

目的:本研究旨在解释肢体攻击、言语攻击、情绪不成熟和撒谎行为在巴基斯坦旁遮普省青少年和学生情绪虐待与犯罪倾向的预测关系中的作用。方法:收集费萨拉巴德和巴哈瓦尔布尔两所监狱关押的232名青少年的数据。通过有目的抽样,选取276名公立学校学生作为比较样本。比较样本根据社会经济地位、性别、地点和年龄进行匹配。标准化量表的翻译(乌尔都语)版本被用来测量各自的构念。通过通径分析,探讨说谎、情绪不成熟和肢体语言攻击在情绪虐待与青少年犯罪倾向之间的中介作用。通过多组分析来确定青少年和学生各路径的强度和显著性。结果:情绪虐待正向预测青少年和学生的犯罪倾向和情绪成熟度,撒谎作为人格特质,肢体语言攻击在这一关系中起中介作用。情绪成熟度的下降是青少年犯罪倾向的一个更强的预测因素,而肢体语言攻击在学生中起着更强的作用。结论:本研究证实了情绪虐待对青少年犯罪倾向的间接影响。本研究还强调了情绪虐待对青少年罪犯情绪成熟的强烈影响,并支持在处理青少年时使用积极方法的重要性,特别是学校工作人员和临床心理学家在与有问题行为的青少年互动时。
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引用次数: 0
Neuromodulation as a Potential Intervention for Children With Attention-Deficit/Hyperactivity Disorder. 神经调节作为儿童注意缺陷/多动障碍的潜在干预措施。
IF 0.8 Q4 PSYCHIATRY Pub Date : 2025-01-01 DOI: 10.5765/jkacap.240039
Chan-Mo Yang, Jun Won Kim

This review examines the therapeutic potential of neuromodulation methods, including neurofeedback, transcranial direct current stimulation (tDCS), and transcranial magnetic stimulation (TMS), as non-pharmacological interventions for children with attention-deficit/hyperactivity disorder (ADHD). A comprehensive review of current studies was conducted, focusing on each technique's mechanism, application, and efficacy in managing ADHD symptoms and cognitive deficits. Studies included human participants with ADHD, evaluating changes in symptom severity and cognitive outcomes. Neurofeedback demonstrated efficacy in symptom reduction, particularly when combined with pharmacotherapy, yielding sustained improvements. tDCS showed moderate efficacy, especially in attention and impulsivity control; however, variability in protocols and pediatric response highlights the need for standardization. TMS exhibited mixed outcomes, with high-frequency TMS targeting the dorsolateral prefrontal cortex indicating potential cognitive benefits, though results were inconsistent across studies. Neuromodulation presents a promising complementary approach for ADHD treatment in children, potentially addressing limitations of pharmacotherapy. Future research should focus on optimizing stimulation parameters, increasing sample sizes, and refining methodologies to establish neuromodulation as part of standard ADHD treatment protocols.

本文综述了神经调节方法的治疗潜力,包括神经反馈、经颅直流电刺激(tDCS)和经颅磁刺激(TMS),作为非药物干预治疗儿童注意力缺陷/多动障碍(ADHD)。对目前的研究进行了全面的回顾,重点关注每种技术在治疗ADHD症状和认知缺陷方面的机制、应用和功效。研究包括患有多动症的人类参与者,评估症状严重程度和认知结果的变化。神经反馈证明了症状减轻的有效性,特别是与药物治疗联合使用时,产生了持续的改善。tDCS效果中等,尤其在注意和冲动控制方面;然而,方案和儿童反应的可变性突出了标准化的必要性。经颅磁刺激显示出不同的结果,高频经颅磁刺激针对背外侧前额皮质表明潜在的认知益处,尽管研究结果不一致。神经调节为儿童ADHD治疗提供了一种有希望的补充方法,可能解决药物治疗的局限性。未来的研究应侧重于优化刺激参数,增加样本量,并改进方法,以建立神经调节作为标准ADHD治疗方案的一部分。
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引用次数: 0
Neurocognitive Profiles of Early Adulthood Attention-Deficit/Hyperactivity Disorder. 成年早期注意力缺陷/多动障碍的神经认知特征。
IF 0.8 Q4 PSYCHIATRY Pub Date : 2025-01-01 DOI: 10.5765/jkacap.240025
Heesung So, Soon-Beom Hong

Objectives: This study examined the neurocognitive profiles of early adulthood attention-deficit/hyperactivity disorder (ADHD) patients using the Korean version of the Wechsler Adult Intelligence Scale, 4th Edition (K-WAIS-IV) and Continuous Performance Test 3rd Edition (CPT-3) assessment results.

Methods: A total of 105 individuals underwent the K-WAIS-IV assessment, and 68 participants completed the CPT-3. We examined the differences between intelligence subindex scores using paired t-tests and applied Pearson's correlation analysis to determine the correlation between the K-WAIS-IV and CPT-3 scores.

Results: Working Memory Index scores were significantly lower than Verbal Comprehension Index scores, whereas Processing Speed Index (PSI) scores were significantly lower than all three other subindex scores. Significant negative correlations were found between all four K-WAIS-IV subindex scores and the CPT-3 scores for Detectability, Omissions, Commissions, Perseverations, Hit Reaction Time, Hit Reaction Time Standard Deviation, and Variability.

Conclusion: The PSI of the K-WAIS-IV can be considered a useful predictor in early adulthood ADHD patients combined with the CPT-3 examination.

目的:本研究采用韩国版韦氏成人智力量表第4版(K-WAIS-IV)和连续表现测试第3版(CPT-3)评估结果,对成年早期注意缺陷/多动障碍(ADHD)患者的神经认知特征进行了研究。方法:共105人接受K-WAIS-IV评估,68人完成CPT-3。我们使用配对t检验来检验智力子指标得分之间的差异,并应用Pearson相关分析来确定K-WAIS-IV和CPT-3得分之间的相关性。结果:工作记忆指数得分显著低于言语理解指数得分,而加工速度指数(PSI)得分显著低于其他三个子指数得分。所有四个K-WAIS-IV子指数得分与CPT-3得分之间存在显著的负相关,包括可探测性、遗漏、委员会、持久性、击中反应时间、击中反应时间标准差和变异性。结论:结合CPT-3检查,K-WAIS-IV的PSI可被认为是成年早期ADHD患者的有用预测因子。
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引用次数: 0
Emerging Breakthroughs in Pediatric Attention-Deficit/Hyperactivity Disorder Treatment. 儿童注意力缺陷/多动障碍治疗的新突破。
IF 0.8 Q4 PSYCHIATRY Pub Date : 2025-01-01 DOI: 10.5765/jkacap.240044
Chan-Mo Yang
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引用次数: 0
Depression, Anxiety and Associated Factors Among Korean Adolescent Students During COVID-19. COVID-19 期间韩国青少年学生的抑郁、焦虑及相关因素。
IF 0.8 Q4 PSYCHIATRY Pub Date : 2024-10-01 DOI: 10.5765/jkacap.220039
Da-Young Jung, Kyung Hee Yoon, Myeong-Yeon Jo, Hyun-Joo Jeong, Yong-Sil Kweon

Objectives: Depression and anxiety are emotional difficulties that are common among adolescents. Adolescents suffering from depression and anxiety can exhibit problems such as antisocial behavior, aggression, and academic slump. This study aimed to explore the factors influencing adolescents' depression and anxiety during the coronavirus disease 2019 (COVID-19) pandemic.

Methods: This study examined the data from an online student health survey conducted by the Ministry of Education in 2022. The survey participants were 131194 students ranging from the first grade of middle school to the third grade of high school. The influence of each variable on depression and anxiety was examined.

Results: Factors that predicted depression and anxiety were sex (female), grade level (higher), financial difficulties (existing or unknown), physical activity (higher), sleep time (shorter), media usage time (higher), family/friends relationship (worse), and change in the health status of family, friends, and oneself due to COVID-19 (worse).

Conclusion: These results may help identify patterns of depression and anxiety among adolescents caused by COVID-19 and maximize the intervention effect.

目的:抑郁和焦虑是青少年常见的情绪障碍。患有抑郁和焦虑症的青少年会表现出反社会行为、攻击行为和学业低迷等问题。本研究旨在探讨 2019 年冠状病毒病(COVID-19)大流行期间影响青少年抑郁和焦虑的因素:本研究考察了教育部于 2022 年开展的在线学生健康调查数据。调查对象为初中一年级至高中三年级的131194名学生。研究了各变量对抑郁和焦虑的影响:结果:预测抑郁和焦虑的因素有性别(女性)、年级(较高)、经济困难(现有或未知)、体育活动(较多)、睡眠时间(较短)、媒体使用时间(较多)、家庭/朋友关系(较差),以及 COVID-19 导致的家人、朋友和自己的健康状况变化(较差):这些结果有助于识别 COVID-19 导致的青少年抑郁和焦虑的模式,并最大限度地提高干预效果。
{"title":"Depression, Anxiety and Associated Factors Among Korean Adolescent Students During COVID-19.","authors":"Da-Young Jung, Kyung Hee Yoon, Myeong-Yeon Jo, Hyun-Joo Jeong, Yong-Sil Kweon","doi":"10.5765/jkacap.220039","DOIUrl":"https://doi.org/10.5765/jkacap.220039","url":null,"abstract":"<p><strong>Objectives: </strong>Depression and anxiety are emotional difficulties that are common among adolescents. Adolescents suffering from depression and anxiety can exhibit problems such as antisocial behavior, aggression, and academic slump. This study aimed to explore the factors influencing adolescents' depression and anxiety during the coronavirus disease 2019 (COVID-19) pandemic.</p><p><strong>Methods: </strong>This study examined the data from an online student health survey conducted by the Ministry of Education in 2022. The survey participants were 131194 students ranging from the first grade of middle school to the third grade of high school. The influence of each variable on depression and anxiety was examined.</p><p><strong>Results: </strong>Factors that predicted depression and anxiety were sex (female), grade level (higher), financial difficulties (existing or unknown), physical activity (higher), sleep time (shorter), media usage time (higher), family/friends relationship (worse), and change in the health status of family, friends, and oneself due to COVID-19 (worse).</p><p><strong>Conclusion: </strong>These results may help identify patterns of depression and anxiety among adolescents caused by COVID-19 and maximize the intervention effect.</p>","PeriodicalId":42806,"journal":{"name":"Journal of the Korean Academy of Child and Adolescent Psychiatry","volume":"35 4","pages":"230-242"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11456651/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Managing Aggressive Behavior in Adolescents With Autism Spectrum Disorder: Pharmacological and Non-Pharmacological Approaches. 管理自闭症谱系障碍青少年的攻击行为:药物和非药物疗法。
IF 0.8 Q4 PSYCHIATRY Pub Date : 2024-10-01 DOI: 10.5765/jkacap.240026
Christopher Ade Putra Purba, Nining Febriyana, Yunias Setiawati

Adolescents diagnosed with autism spectrum disorder (ASD) often encounter significant challenges, particularly aggressive behaviors that persist into adulthood and profoundly affect their daily functioning and quality of life. These behaviors not only pose hurdles for affected individuals but also present considerable challenges for caregivers and families. Managing aggression in adolescents with ASD requires comprehensive treatment approaches encompassing both non-pharmacological and pharmacological interventions. This paper reviews current interventions that have proven to be effective through empirical studies in managing aggression among adolescents with ASD. By synthesizing evidence-based practices, this study underscores the importance of a multidisciplinary approach involving medical, psychological, and educational interventions to effectively manage aggression among adolescents with ASD. It aimed to inform clinicians, educators, and caregivers of practical strategies and evidence-based interventions to address aggression in this population.

被诊断患有自闭症谱系障碍(ASD)的青少年经常会遇到巨大的挑战,尤其是成年后仍然存在的攻击性行为,严重影响了他们的日常功能和生活质量。这些行为不仅给患者带来障碍,也给照顾者和家人带来巨大挑战。处理患有自闭症的青少年的攻击行为需要综合的治疗方法,包括非药物和药物干预。本文回顾了目前通过实证研究证明对控制 ASD 青少年攻击行为有效的干预措施。通过综合循证实践,本研究强调了多学科方法(包括医疗、心理和教育干预)对于有效控制 ASD 青少年攻击行为的重要性。研究旨在向临床医生、教育工作者和护理人员介绍解决该人群攻击行为的实用策略和循证干预措施。
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引用次数: 0
Sex Differences in Risk Factors for Generalized Anxiety Disorder in Korean Adolescents. 韩国青少年患广泛性焦虑症风险因素的性别差异。
IF 0.8 Q4 PSYCHIATRY Pub Date : 2024-10-01 DOI: 10.5765/jkacap.240033
Yea-Ju Jin, JooYong Park

Objectives: This study aimed to examine sex differences in the risk factors associated with generalized anxiety disorder (GAD) among Korean adolescents to provide insights for drafting more effective prevention strategies.

Methods: Data from 51845 middle and high school students in the 18th Korea Youth Risk Behavior Web-based Survey were analyzed. GAD was assessed using the 7-item Generalized Anxiety Disorder tool, and factors such as grade, academic performance, economic status, living arrangements, smoking, drinking, sexual experience, and physical activity were included. The prevalence of GAD and its association with these factors were compared between male and female students using chi-square tests and logistic regression. Odds ratios were compared statistically to identify sex-specific differences.

Results: GAD prevalence was higher among girls (42.1%) than boys (30.1%). Both sexes showed increased GAD risk with lower academic performance, lower economic status, smoking, drinking, and sexual experience. Boys living apart from their families had a higher GAD risk, but this was not significant for girls. Additionally, smoking and drinking were associated with a higher increase in GAD risk in girls than in boys.

Conclusion: This study underscores the importance of considering sex differences in the prevention of GAD among adolescents. Tailored sex-specific interventions are crucial for effective prevention and management of GAD in Korean adolescents.

研究目的本研究旨在探讨韩国青少年中与广泛性焦虑症(GAD)相关的风险因素的性别差异,从而为起草更有效的预防策略提供见解:分析了第 18 次韩国青少年危险行为网络调查中 51845 名初高中学生的数据。方法:分析了第 18 次韩国青少年危险行为网络调查中 51845 名初高中学生的数据,使用 7 项广泛性焦虑症工具对 GAD 进行评估,并纳入了年级、学习成绩、经济状况、生活安排、吸烟、饮酒、性经历和体育活动等因素。采用卡方检验和逻辑回归法比较了男女学生的 GAD 患病率及其与这些因素的关系。统计比较了几率比,以确定性别差异:结果:女生的 GAD 患病率(42.1%)高于男生(30.1%)。在学习成绩较差、经济地位较低、吸烟、饮酒和有性经历的情况下,两性患 GAD 的风险都有所增加。与家人分开居住的男孩患 GAD 的风险更高,但这一点在女孩中并不显著。此外,与男孩相比,女孩吸烟和酗酒导致 GAD 风险增加的相关性更高:本研究强调了在预防青少年 GAD 时考虑性别差异的重要性。针对不同性别的干预措施对于有效预防和管理韩国青少年的 GAD 至关重要。
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引用次数: 0
Investigating Attention Deficit Hyperactivity Disorder Symptoms, Emotional Dysregulation and Family Functioning in Children: A Community-Based Study in Elementary Schools in Surabaya, Indonesia. 调查儿童的注意力缺陷多动障碍症状、情绪失调和家庭功能:印度尼西亚泗水小学社区研究》。
IF 0.8 Q4 PSYCHIATRY Pub Date : 2024-10-01 DOI: 10.5765/jkacap.240015
Yunias Setiawati, Dhenni Hartopo, Friandi Danang Rabitho, Winson Chuanardi

Objectives: Research on emotional dysregulation related to attention deficit hyperactivity disorder (ADHD) symptoms and its effects on family functioning in children is scarce. This is the first study conducted in Indonesia to examine the intricate relationships between ADHD symptoms, emotional regulation, and family functioning in children.

Methods: A cross-sectional survey was conducted involving primary caregivers of children aged 9-13 years old across three elementary schools in Surabaya, using validated questionnaires comprising the Indonesian ADHD Rating Scale, Emotion Regulation Checklist, and Family APGAR scale.

Results: The findings revealed a positive association between ADHD features and the emotional lability/negativity subscale (ERLN) (r=0.528; p<0.001), but not the emotion regulation subscale (EREG). Moreover, family functioning positively correlated with ERLN (r= -0.269; p=0.003) and negatively correlated with EREG (r=0.331; p<0.001). Parental education emerged as a significant demographic factor, with higher education levels linked to better emotion regulation (r=0.297; p=0.001).

Conclusion: These findings underscore the importance of addressing ADHD symptoms and emotional dysregulation in children in order to enhance family functioning and overall well-being. Implications for future research and interventions targeting emotion regulation, especially in children with ADHD and their families, are also discussed.

研究目的有关与注意力缺陷多动障碍(ADHD)症状相关的情绪失调及其对儿童家庭功能影响的研究很少。这是在印度尼西亚开展的第一项研究,旨在探讨儿童注意力缺陷多动障碍(ADHD)症状、情绪调节和家庭功能之间错综复杂的关系:方法:对泗水三所小学 9-13 岁儿童的主要照顾者进行了一项横断面调查,使用的有效问卷包括印尼多动症评分量表、情绪调节核对表和家庭 APGAR 量表:结果:研究结果表明,多动症特征与情绪易变/消极分量表(ERLN)之间存在正相关(r=0.528;p):这些发现强调了解决儿童多动症症状和情绪失调问题的重要性,以增强家庭功能和整体福祉。此外,还讨论了针对情绪调节的未来研究和干预措施的意义,尤其是对多动症儿童及其家庭的影响。
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引用次数: 0
期刊
Journal of the Korean Academy of Child and Adolescent Psychiatry
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