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Analysis of the Status and Future Direction for Digital Therapeutics in Children and Adolescent Psychiatry. 数字治疗在儿童和青少年精神病学中的现状和未来方向分析。
IF 2 Q4 PSYCHIATRY Pub Date : 2023-10-01 DOI: 10.5765/jkacap.230044
Haemi Choi, Bora Kim, Insoo Kim, Jae-Gu Kang, Yoonjae Lee, Hyowon Lee, Min-Hyeon Park

Digital therapeutics based on software, such as artificial intelligence, virtual reality, games, and smartphone applications, are in the spotlight as new therapeutic alternatives in child and adolescent psychiatry. It draws attention to overcoming conventional therapeutics' limitations, such as toxicity, cost, and accessibility, and encourages patients to participate in the treatment attractively. The growth potential of the digital therapeutics market for psychiatric disorders in children and adolescents in Korea and abroad has been highlighted. Clinical studies and Food and Drug Administration approvals for digital therapeutics have increased, and cases approved by the Ministry of Food and Drug Safety have emerged in Korea. As seen above, digital transformation in child and adolescent psychiatry will change treatment paradigms significantly. Therefore, as this new field has just begun to emerge, it is necessary to verify the effectiveness and scope of the application of digital therapeutics and consider preparing a compensation system and institutional arrangements. Accordingly, this study analyzed the development trends and application status of digital therapeutics in children and adolescents and presented limitations and development directions from the perspective of application in healthcare. Further, the study is expected to identify the utility and limitations of digital therapeutics for children and adolescents and establish effective application measures.

基于软件的数字疗法,如人工智能、虚拟现实、游戏和智能手机应用程序,作为儿童和青少年精神病学的新治疗替代品,备受关注。它提请人们注意克服传统疗法的局限性,如毒性、成本和可及性,并鼓励患者有吸引力地参与治疗。韩国国内外儿童和青少年精神障碍数字治疗市场的增长潜力已经凸显。临床研究和食品药品监督管理局对数字疗法的批准有所增加,韩国出现了食品药品安全部批准的病例。如上所述,儿童和青少年精神病学的数字化转型将显著改变治疗模式。因此,由于这一新领域刚刚开始出现,有必要验证数字疗法的有效性和应用范围,并考虑制定补偿制度和制度安排。因此,本研究分析了数字治疗在儿童和青少年中的发展趋势和应用现状,并从医疗保健应用的角度提出了局限性和发展方向。此外,该研究有望确定数字疗法对儿童和青少年的效用和局限性,并制定有效的应用措施。
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引用次数: 0
Psychological Risk and Protective Factors for Suicidal Ideation: A Study in an Adolescent Sample in an Insular Context. 自杀意念的心理风险和保护因素:在岛屿环境下对青少年样本的研究。
IF 2 Q4 PSYCHIATRY Pub Date : 2023-10-01 DOI: 10.5765/jkacap.230031
Ana Margarida Cunha, Claudia Carmo, Marta Bras

Objectives: Adolescents are at risk of suicide. As suicide is a multifactorial process, risk and protective factors are relevant constructs for suicide prediction. This study explored the effects of risk and protective factors on suicidal ideation in adolescents on the island of São Miguel (Azores).

Methods: A sample of 750 adolescents (male: n=358; 47.7%; mean age=14.67 years; standard deviation=1.85 years) from the island of São Miguel (Azores) completed several measures related to suicidal ideation and associated factors. Using a cross-sectional design, this study conducted descriptive, correlational, predictive, mediation, and moderation analyses.

Results: Adolescents generally displayed high levels of risk and protective factors; an indicative proportion exhibited significant suicidal ideation with females presenting the greatest vulnerability. Furthermore, the results highlight that depression is the best predictor of suicidal ideation, however, the association between these variables is mediated.

Conclusion: The data corroborate that the suicidal reality of adolescents in the Autonomous Region of the Azores is worrisome. Having substantiated the complexity of the suicidal context in young people in the present research, the need to continue studying risk/protective factors in this area is supported.

目标:青少年有自杀的危险。由于自杀是一个多因素的过程,风险和保护因素是自杀预测的相关因素。本研究探讨了风险和保护因素对圣米格尔岛(亚速尔群岛)青少年自杀意念的影响。本研究采用横断面设计,进行了描述性、相关性、预测性、中介性和适度性分析。结果:青少年通常表现出高水平的风险和保护因素;一个指示性比例表现出显著的自杀意念,其中女性表现出最大的脆弱性。此外,研究结果强调,抑郁是自杀意念的最佳预测因素,然而,这些变量之间的联系是中介的。结论:数据证实,亚速尔群岛自治区青少年自杀的现实令人担忧。在本研究中证实了年轻人自杀背景的复杂性后,有必要继续研究这一领域的风险/保护因素。
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引用次数: 0
Coping With Changes in the World Affecting Children. 应对影响儿童的世界变化。
IF 2 Q4 PSYCHIATRY Pub Date : 2023-10-01 DOI: 10.5765/jkacap.230060
Hee Jeong Yoo
Recently, the educational system in Korea has faced significant turmoil related to teacher suicides, heightened awareness of the harassment they endure from parents, and their deep frustration and agony regarding the harsh environment they encounter. The school system is an integral part of the daily lives of children and a critical factor in their development. Therefore, I am deeply concerned about the transformations in classroom dynamics, as reported by teachers following these tragic events. Children must learn from both positive and negative experiences to develop into well-rounded individuals. The process of recovering from minor everyday stresses and conflicts, as well as self-reflection on their own behavior, plays an important role in enhancing their mental resilience and ability to navigate life challenges. Similar to doctor-patient relationships, the relationships within the classroom should maintain clear boundaries among teachers, parents, and children to ensure a safe and effective learning environment. However, it appears that some children are becoming overprotected, and some parents are overly eager to shield them from negative experiences in the outer world. At times, heightened parental anxiety leads to projecting conflicts onto potential authorities, even accusing them of any disadvantages faced by their children. The world surrounding children and adolescents is evolving more rapidly than that of adults. Recent decades have brought about changes in the classroom, mirroring the rapid transitions in society, both positive and negative. For example, an overprotective environment may be a unintended consequence of collective efforts to protect people from significant trauma and stress. Instances of school violence and children adopting a sense of entitlement toward authority figures may reflect an unhealthy shift in the social values regarding power and an excessive focus on external factors, rather than fostering self-reflection. The uncontrollable influence of social media, especially the indiscriminate exposure to harmful content before critical thinking abilities fully develop in the brain, poses a significant challenge. Regulating the production, reproduction, and imitation of this content is proving to be as complex as addressing global climate change. Mental health professionals may, at times, feel helpless in the face of this overwhelming tide. In this issue, our journal addresses another major change in the world affecting children, under the theme of “Digital Therapeutics and Digital Adversity.” It includes current knowledge regarding augmented and virtual reality, digital media used for therapeutic purposes, and metaverses, all within the context of their incorporation into the lives of children as a novel dimension of reality. We have strived to provide a multidisciplinary perspective, encompassing both positive and negative aspects of these developments. Often, progress arises dialectically in response to problems or
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引用次数: 0
Digital Solutions for Mental Health: A Critical Look at the Present Reality. 心理健康的数字解决方案:对当前现实的批判性审视。
IF 2 Q4 PSYCHIATRY Pub Date : 2023-10-01 DOI: 10.5765/jkacap.230059
Eunjoo Kim
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引用次数: 0
How Well Did We Know About Our Communication? “Origins of Human Communication” 我们对沟通有多了解?“人类交流的起源”
IF 2 Q4 PSYCHIATRY Pub Date : 2023-01-01 DOI: 10.5765/jkacap.220042
Jung-Woo Son
Through accurate observation and the results of experimental studies using great apes, the author tells us exactly what we have not known about human communication. The author persuasively conveys to the reader the grand history of developing from great apes’ gestures to human gestures, to human speech. Given that great apes and human gestures were the origin of human voice language, we have once again realized that our language is, after all, an “embodied language.”
通过对类人猿的精确观察和实验研究结果,作者准确地告诉了我们关于人类交流的未知之处。作者向读者娓娓道来从类人猿的手势发展到人类的手势,再到人类语言的宏大历史。考虑到类人猿和人类的手势是人类语音语言的起源,我们再次意识到,我们的语言毕竟是一种“具体化的语言”。
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引用次数: 0
Stimulant Induced Movement Disorders in Attention Deficit Hyperactivity Disorder 注意缺陷多动障碍中兴奋剂引起的运动障碍
IF 2 Q4 PSYCHIATRY Pub Date : 2022-04-01 DOI: 10.5765/jkacap.210034
S. Nam, M. Lim, T. Park
Stimulants, such as amphetamine and methylphenidate, are one of the most effective treatment modalities for attention deficit hyperactivity disorder (ADHD) and may cause various movement disorders. This review discusses various movement disorders related to stimulant use in the treatment of ADHD. We reviewed the current knowledge on various movement disorders that may be related to the therapeutic use of stimulants in patients with ADHD. Recent findings suggest that the use of stimulants and the onset/aggravation of tics are more likely to be coincidental. In rare cases, stimulants may cause stereotypies, chorea, and dyskinesia, in addition to tics. Some epidemiological studies have suggested that stimulants used for the treatment of ADHD may cause Parkinson’s disease (PD) after adulthood. However, there is still a lack of evidence that the use of stimulants in patients with ADHD may cause PD, and related studies are only in the early stages. As stimulants are one of the most commonly used medications in children and adolescents, close observations and studies are necessary to assess the effects of stimulants on various movement disorders, including tic disorders and Parkinson’s disease.
兴奋剂,如安非他命和哌醋甲酯,是治疗注意缺陷多动障碍(ADHD)最有效的方法之一,并可能导致各种运动障碍。这篇综述讨论了与多动症治疗中兴奋剂使用相关的各种运动障碍。我们回顾了目前关于各种运动障碍的知识,这些运动障碍可能与多动症患者使用兴奋剂治疗有关。最近的研究结果表明,兴奋剂的使用和抽搐的发作/加重更可能是巧合。在极少数情况下,兴奋剂除了抽搐外,还可能引起刻板印象、舞蹈病和运动障碍。一些流行病学研究表明,用于治疗多动症的兴奋剂可能会导致成年后的帕金森病(PD)。然而,目前仍缺乏证据表明ADHD患者使用兴奋剂可能导致PD,相关研究仅处于早期阶段。由于兴奋剂是儿童和青少年最常用的药物之一,因此有必要进行密切的观察和研究,以评估兴奋剂对各种运动障碍的影响,包括抽动障碍和帕金森病。
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引用次数: 3
Patterns of Restricted and Repetitive Behaviors in Toddlers and Young Children with Autism Spectrum Disorder 自闭症谱系障碍幼儿的限制性和重复性行为模式
IF 2 Q4 PSYCHIATRY Pub Date : 2022-04-01 DOI: 10.5765/jkacap.220001
Da-Yea Song, Dabin Kim, Hannah J. Lee, Guiyoung Bong, Jae Hyun Han, H. Yoo
Objectives Restricted and repetitive behaviors (RRBs) are a core symptom in the diagnosis of autism spectrum disorder (ASD). The complexity of behavioral patterns has called for the creation of phenotypically homogeneous subgroups among individuals with ASD. The purpose of this study was 1) to investigate the different types of RRBs and 2) to explore whether subgroups created by RRBs would show unique levels of functioning in toddlers and young children with ASD. Methods A total of 313 children with ASD, aged 12–42 months were included in the analysis. The Autism Diagnostic Interview-Revised was used to obtain information on the different types of RRBs by grouping 15 items into six categories. The Vineland Adaptive Behaviors Scale, a parent-reported questionnaire, was used to measure adaptive functioning. A portion of the children were analyzed separately for verbal-related RRBs based on their expressive language level. Two-step cluster analysis using RRB groups as features was used to create subgroups. Analysis of covariance while covarying for age and language was performed to explore the clinical characteristics of each cluster group. Results Sensory-related RRBs were the most prevalent, followed by circumscribed interests, interest in objects, resistance to change, and repetitive body movements. A subset of the children was analyzed separately to explore verbal-related RRBs. Four cluster groups were created based on reported RRBs, with multiple RRBs demonstrating significant delays in adaptive functioning. Conclusion Heterogeneity of RRBs emerges at a young age. The different patterns of RRBs can be used as valuable information to determine developmental trajectories with better implications for treatment approaches.
目的限制和重复行为(RRBs)是自闭症谱系障碍(ASD)诊断的核心症状。行为模式的复杂性要求在ASD患者中建立表型同质的亚群。本研究的目的是1)调查不同类型的RRBs, 2)探索由RRBs产生的亚组是否会在幼儿和ASD幼儿中表现出独特的功能水平。方法对313例年龄12 ~ 42月龄的ASD患儿进行分析。《自闭症诊断访谈-修订版》通过将15个项目分为6类来获取不同类型RRBs的信息。Vineland适应行为量表是一份家长报告的问卷,用于测量适应功能。根据部分儿童的语言表达水平,对他们的语言相关RRBs进行单独分析。采用两步聚类分析,以RRB组为特征创建子组。对年龄和语言进行协方差分析,探讨每组患者的临床特征。结果感官相关的RRBs最为普遍,其次是限制性兴趣、对物体的兴趣、抗拒改变和重复的身体动作。对一部分儿童进行单独分析,以探索与语言相关的rrb。根据报告的RRBs创建了四个集群组,其中多个RRBs表现出显著的适应性功能延迟。结论RRBs在年轻时出现异质性。RRBs的不同模式可以作为有价值的信息来确定发育轨迹,从而更好地指导治疗方法。
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引用次数: 1
How Must We Prepare in the Next Decades When Caring for Those With Developmental Disabilities: “Grown Up” (2018) 如何在未来几十年为照顾发育性残疾人士做好准备:《长大成人》(2018)
IF 2 Q4 PSYCHIATRY Pub Date : 2022-04-01 DOI: 10.5765/jkacap.220007
Jun-Won Hwang
The Guarantee of Rights and Support for Persons with Developmental Disabilities Act was enacted and revised in 2014. However, national measures for persons with developmental disabilities remain insufficient. In the film, “Grown Up,” director Hyeyoung Jang filmed the daily life of her sister, who has developmental disabilities. She raised not only the issue of institutionalization in people with developmental disabilities in Korea but also the issue of a lack of policies that would be essential to them and their family members. In the future, I hope that as experts, child and adolescent psychiatrists in Korea will pay more attention to the lives of people with developmental disabilities outside the clinic and propose policies to help them and their family members.
2014年颁布并修订了《发育障碍者权利保障法》。然而,针对发育性残疾者的国家措施仍然不足。在电影《长大了》中,导演张惠英拍摄了患有发育障碍的妹妹的日常生活。她不仅提出了韩国发育障碍者的收容问题,还提出了对他们及其家庭成员至关重要的政策缺乏的问题。未来,我希望作为专家,韩国的儿童和青少年精神科医生能够更多地关注诊所之外的发展障碍患者的生活,并提出帮助他们及其家人的政策。
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引用次数: 0
Concept of Synchronized Individuation Based on the Characters in a Movie and a Fairy Tale 基于电影和童话人物的同步个性化概念
IF 2 Q4 PSYCHIATRY Pub Date : 2022-04-01 DOI: 10.5765/jkacap.220004
D. Moon, G. Bahn
Objectives Among adolescent development tasks, being independent of parents is an essential process for emotional and physical separation. There are many conflicts of separation and individuation between parents and adolescents; however, most clinicians explore the process of separation and individuation only from adolescents’ perspective. Whether simultaneously or sequentially, separation-individuation occurs between adolescents and parents, respectively. The authors have already introduced the theory of synchronized individuation in a clinical case to explain the concept of this intersubjective phenomena. This study also attempts to prove the synchronized individuation theory through the interaction of characters in a movie and a fairy tale. Methods The authors present the basis for the theory of synchronized individuation of adolescence through the growing process of Mason Junior, the main character of the movie “Boyhood,” and from the process of the separation of a hen, Sprout, and an orphaned duckling in “The hen who dreamed she could fly.” Results Synchronized individuation was developed and observed from Mason, the son’s perspective in “Boyhood,” and Sprout, the mother’s subjective perspective in the story of the hen. Conclusion Increasing conflict and mutual impact in the relationship between adolescents and parents, ambivalent feelings for separation, selective identification of each other, mutual respect through mutual recognition, and role changes in relationship position were confirmed. Sons and mothers were individualized with synchronization.
在青少年发展任务中,脱离父母是情感和身体分离的重要过程。父母与青少年之间存在着许多分离和个性化的冲突;然而,大多数临床医生只从青少年的角度来探讨分离和个性化的过程。无论是同时发生还是先后发生,分离-个性化分别发生在青少年和父母之间。作者已经在一个临床案例中引入了同步个体化理论来解释这种主体间现象的概念。本研究还试图通过电影和童话人物的互动来证明同步个性化理论。方法通过电影《少年时代》中主人公小梅森的成长过程,以及电影《梦想飞翔的母鸡》中一只名叫斯普劳特的母鸡和一只失去双亲的小鸭子的分离过程,为青少年同步个性化理论提供依据。结果同步个性化从《少年时代》中儿子的视角梅森和母鸡故事中母亲的主观视角斯普劳特得到了发展和观察。结论青少年与父母关系中冲突和相互影响的增加、分离感的矛盾、对彼此的选择性认同、通过相互承认而产生的相互尊重、以及关系位置的角色变化均得到了证实。儿子和母亲的个体化与同步。
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引用次数: 0
Beyond Statistics 除了统计
IF 2 Q4 PSYCHIATRY Pub Date : 2022-01-01 DOI: 10.5765/jkacap.220010
H. Yoo
Statistics based on measurable data protect us from the temptation of saying our intuition is true. However, they cannot sometimes reveal the truths hidden behind a phenomenon. Sometimes, data cannot be collected in the middle of an ongoing phenomenon. Many factors make the process hard, including practical difficulties in data collection, available measures, age of participants, various biases of data collection, and representativeness of the sample. For example, how can we measure the active changes in the brain of very young infants when they are developing basic social emotions, learning a language at the single word level, and consolidating secured attachment with their primary caregivers? How can we quantify ever-changing emotional reciprocity during the rapprochement period of 2-year-old toddlers and their parents? Even if we can capture a certain aspect of brain activities during the early developmental stage, a more robust story and context are attenuated within the data, and its implication in development might lose its depth. As another example, it has been more than 2 years since the COVID-19 pandemic started, and while some children are experiencing both physical and mental issues, others are not; statistics have not been able to capture or integrate what we experience and feel in everyday life. There has been a tremendous increase in cases of neurodevelopmental disorders, including autism spectrum disorder, in the last four decades. Nonetheless, the statistics per se are insufficient to understand the situation without knowing the why behind the rapid increase, which is extremely hard to answer clearly. We know that children in Ukraine are facing tremendous crises in the face of war, and the data are unavailable and even powerless in such a rigorous existential reality. An in-depth understanding of typical developmental trajectories is an essential research area for atypical development and decoding psychopathology in child psychiatry. Studies have tried to prove the developmental process both in behavior and at the brain level. Many outstanding longitudinal studies examining developmental brain structure or connectivity changes have been published, with some examining brain changes associated with specific traits, such as reading, arithmetic ability, and preterm birth [1-3]. Prospective follow-up databases for brain development have been launched to set up more comprehensive insight into human brain development in an unbiased setting [4]. Various experimental models were developed and utilized to reproduce developmental processes in laboratory settings, from classic examples such as Ainsworth’s strange situation procedure to examine mother-child attachment patterns and false belief tasks to test the theory of mind to more complicated cognitive tasks. These might be researchers’ trials to make more abstract issues more concrete and transform further intersubjective phenomena into more visible, ubiquitous ones. With these attempts, w
基于可测量数据的统计数据保护我们免受说直觉是正确的诱惑。然而,它们有时无法揭示隐藏在现象背后的真相。有时,在正在进行的现象中无法收集数据。许多因素使这一过程变得困难,包括数据收集的实际困难、可用的措施、参与者的年龄、数据收集的各种偏差和样本的代表性。例如,当非常年幼的婴儿正在发展基本的社会情感、学习单个单词水平的语言、巩固与主要照顾者的安全依恋关系时,我们如何测量他们大脑中的活跃变化?我们如何量化两岁幼童和父母之间不断变化的情感互惠?即使我们能够在早期发育阶段捕捉到大脑活动的某些方面,在数据中也会减弱更强大的故事和背景,其在发展中的含义可能会失去其深度。另一个例子是,自2019冠状病毒病大流行开始以来已经两年多了,虽然有些儿童出现了身体和精神问题,但有些儿童没有;统计数据无法捕捉或整合我们在日常生活中的经历和感受。在过去的四十年里,包括自闭症谱系障碍在内的神经发育障碍病例急剧增加。然而,如果不知道快速增长背后的原因,统计数据本身不足以理解情况,这很难回答清楚。我们知道,面对战争,乌克兰的儿童正面临着巨大的危机,而在如此严峻的生存现实中,这些数据是不可获得的,甚至是无能为力的。深入了解典型的发展轨迹是非典型发展和解码儿童精神病学精神病理学的重要研究领域。研究试图在行为和大脑层面上证明这一发展过程。已经发表了许多杰出的关于大脑结构发育或连通性变化的纵向研究,其中一些研究了与特定特征相关的大脑变化,如阅读、算术能力和早产[1-3]。脑发育的前瞻性随访数据库已经启动,以便在无偏倚的环境下更全面地了解人类大脑发育[4]。各种各样的实验模型被开发出来并用于在实验室环境中再现发展过程,从经典的例子,如安斯沃思的奇怪情况程序来检查母子依恋模式和错误信念任务来测试心理理论到更复杂的认知任务。这些可能是研究人员试图将更抽象的问题变得更具体,并将进一步的主体间现象转化为更可见、更普遍的现象。通过这些尝试,我们现在知道儿童的皮质厚度随着他们的发育而变化,特定大脑区域的成熟取决于认知特征。本期有两篇关于青少年分离-个性化(SSI)过程中的同步的文章,以治疗青少年患者和代表电影和童话故事情节中的概念为背景。与早期发展过程中的许多概念一样,它只是通过与患者合作或象征性文本(包括艺术或文学)反映人类经验的可观察的沉思。这些文章让我思考如何通过对可测量数据的分析和对治疗患者的积极过程中观察到的现象进行逻辑分析来协调研究。后者应该成为发展更普遍的实证研究的重要推动力。儿童精神病学研究的最终目的是了解儿童的生活,并通过承认生物过程及其与环境的相互作用来改善儿童的生活。例如,我们可以在思考这些文章的基础上设置下一个问题,例如如何将SSI形式化,如何证明SSI在大多数家庭中是普遍的,哪个大脑区域对这种现象的贡献最大,以及如何跟进SSI从幼儿期到青春期的纵向过程。怎样才能做到呢?数字技术与情感传感器相结合,作为一个快速发展的话题,这些天,在测量活跃的,正在进行的现象,以最小的偏见或绕过劳动密集型的实验室工作,这是一篇开放获取的文章,在知识共享署名非商业许可(https://creativecommons.org/licenses/by-nc/4.0)的条款下分发,允许无限制的非商业使用,分发,并在任何媒介上复制。只要正确引用原文。除了统计
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引用次数: 0
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Journal of the Korean Academy of Child and Adolescent Psychiatry
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