Oral candidiasis is a fungal infection of the oral cavity caused by Candida albicans. Currently used antifungal drugs fail to treat oropharyngeal candidiasis. Herbal remedies are found to be safe and effective to treat bleeding gums, halitosis, mouth ulcers, and reduce tooth decay. Cardamom is known to possess antimicrobial, antioxidant, and immunomodulatory activity. In an in vitro study, we aim to evaluate the antifungal potential of cardamom-based DenteezTM mouthwash against opportunistic fungal infections in the oral cavity. Five Candida species were included in the study: namely C. albicans, C. tropicalis, C. krusei, C. parapsilosis, and C. glabrata. Additionally, 54 clinical isolates obtained from oral cavity of healthy individuals and patients suffering from oral candidiasis were randomly selected and included. Various antifungal agents tested included fluconazole, itraconazole, ketoconazole, miconazole, and amphotericin B. Minimum inhibitory concentration (MIC) and time-kill assay were performed as per standard guidelines. The MIC obtained for fluconazole against different Candida species was 1.25 µg/ml. The MIC of azole drugs was in the range of 0.312–0.62 µg/ml. The MIC of DenteezTM mouthwash was determined as 1.25%. The clinical isolates of Candida showed major resistance to fluconazole (75.9%) and absolute susceptibility to amphotericin B. DenteezTM was found effective in inhibiting 98.2% of the clinical isolates. DenteezTM mouthwash showed time-dependent inhibition of all Candida species. The mouthwash has comparable efficacy to that of other routinely used antifungal agents. DenteezTM can be effectively used to deal with oral candidiasis and antifungal resistance.
{"title":"The Antifungal Potential of Cardamom-based DenteezTM Mouthwash Against Opportunistic Fungal Infections in the Oral Cavity","authors":"Matthan Tharakan, Manohar S. Kugaji, Kishore Bhat, Prashanth Varkey, Mayuri Joshi, Bhagyashree Nanda","doi":"10.1177/23202068231194895","DOIUrl":"https://doi.org/10.1177/23202068231194895","url":null,"abstract":"Oral candidiasis is a fungal infection of the oral cavity caused by Candida albicans. Currently used antifungal drugs fail to treat oropharyngeal candidiasis. Herbal remedies are found to be safe and effective to treat bleeding gums, halitosis, mouth ulcers, and reduce tooth decay. Cardamom is known to possess antimicrobial, antioxidant, and immunomodulatory activity. In an in vitro study, we aim to evaluate the antifungal potential of cardamom-based DenteezTM mouthwash against opportunistic fungal infections in the oral cavity. Five Candida species were included in the study: namely C. albicans, C. tropicalis, C. krusei, C. parapsilosis, and C. glabrata. Additionally, 54 clinical isolates obtained from oral cavity of healthy individuals and patients suffering from oral candidiasis were randomly selected and included. Various antifungal agents tested included fluconazole, itraconazole, ketoconazole, miconazole, and amphotericin B. Minimum inhibitory concentration (MIC) and time-kill assay were performed as per standard guidelines. The MIC obtained for fluconazole against different Candida species was 1.25 µg/ml. The MIC of azole drugs was in the range of 0.312–0.62 µg/ml. The MIC of DenteezTM mouthwash was determined as 1.25%. The clinical isolates of Candida showed major resistance to fluconazole (75.9%) and absolute susceptibility to amphotericin B. DenteezTM was found effective in inhibiting 98.2% of the clinical isolates. DenteezTM mouthwash showed time-dependent inhibition of all Candida species. The mouthwash has comparable efficacy to that of other routinely used antifungal agents. DenteezTM can be effectively used to deal with oral candidiasis and antifungal resistance.","PeriodicalId":43017,"journal":{"name":"Journal of Advanced Oral Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87655771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-07DOI: 10.1177/23202068231195181
Anisa H. AlBadr, Nabeel F. Talic
To determine the difference in the reflected color coordinates and to compare the translucency and opacity of different as-received ceramic brackets using a spectrophotometer. Four types of ceramic brackets were investigated in this in vitro study. A total of 72 ceramic brackets were examined using a spectrophotometer. Reflected color coordinates of the labial side of bracket were measured according to the Commission Internationale de l’Eclairage (CIE) color scale. Color difference between brackets was calculated using the equation: Δ E*ab = [(Δ L*)2 + (Δ a*)2 + (Δ b*)2] 1/2. Translucency parameter (TP) and opalescence parameter (OP) were calculated to determine translucency and opacity of the brackets, respectively. Data was collected and analyzed using IBM SPSS V25. The significance level was set at p ≤ .05. One-way ANOVA and post hoc multiple comparison tests were utilized. The range for CIE L* (lightness) was 62.69 to 58.83, for a* (red–green parameter) −0.33 to −2.9 and for b* (yellow–blue parameter) −2.19 to 2.29. All these color co-ordinates were influenced by bracket brand ( p < .05). DISCREET™ showed the highest TP = 16.342 and Symetri™ Clear showed the lowest = 10.823. The OP values ranged between 1.783 and 3.781 and Symetri™ Clear showed the highest OP. Color coordinates, TP, and OP of esthetic brackets investigated with a spectrophotometer were significantly different and influenced by the material microstructure and/or manufacturing process.
{"title":"The Optical Translucency, Opalescence, and Reflectance of Different As-Received Ceramic Brackets: A Spectrophotometer Study","authors":"Anisa H. AlBadr, Nabeel F. Talic","doi":"10.1177/23202068231195181","DOIUrl":"https://doi.org/10.1177/23202068231195181","url":null,"abstract":"To determine the difference in the reflected color coordinates and to compare the translucency and opacity of different as-received ceramic brackets using a spectrophotometer. Four types of ceramic brackets were investigated in this in vitro study. A total of 72 ceramic brackets were examined using a spectrophotometer. Reflected color coordinates of the labial side of bracket were measured according to the Commission Internationale de l’Eclairage (CIE) color scale. Color difference between brackets was calculated using the equation: Δ E*ab = [(Δ L*)2 + (Δ a*)2 + (Δ b*)2] 1/2. Translucency parameter (TP) and opalescence parameter (OP) were calculated to determine translucency and opacity of the brackets, respectively. Data was collected and analyzed using IBM SPSS V25. The significance level was set at p ≤ .05. One-way ANOVA and post hoc multiple comparison tests were utilized. The range for CIE L* (lightness) was 62.69 to 58.83, for a* (red–green parameter) −0.33 to −2.9 and for b* (yellow–blue parameter) −2.19 to 2.29. All these color co-ordinates were influenced by bracket brand ( p < .05). DISCREET™ showed the highest TP = 16.342 and Symetri™ Clear showed the lowest = 10.823. The OP values ranged between 1.783 and 3.781 and Symetri™ Clear showed the highest OP. Color coordinates, TP, and OP of esthetic brackets investigated with a spectrophotometer were significantly different and influenced by the material microstructure and/or manufacturing process.","PeriodicalId":43017,"journal":{"name":"Journal of Advanced Oral Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83439978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.1177/23202068231193606
Javed Ahmad, G. Sajjan, Durga Bhavani Panithini, Madhu Varma, Kalyan Satish R, K. D. Prasad
Endodontically treated teeth display altered tooth structure pertaining to various chemical irrigants and intracanal medicaments. To prevent the compromised adhesive bond, dentin biomodification is indicated. This study was designed to evaluate the influence of dentin biomodification on the fracture resistance of root canal-treated teeth following Delayed Endodontic Sealing (DES). In 50 maxillary central incisors, Class III cavities along with access cavities were prepared. The samples were randomly divided into five groups. Group 1: Intact teeth ( N = 10), Group 2: Immediate Endodontic Sealing (IES) ( N = 10); Group 3: DES after irrigation with 3% NaOCl ( N = 10); Group 4: DES with 2% chlorhexidine (CHX) as a biomodifier ( N = 10) and Group 5: DES with 5% grape seed extract (GSE) as a biomodifier ( N = 10). In Group 2 samples, composite restorations were done prior to irrigation with 3% sodium hypochlorite (NaOCl). Group 3 samples received root canal irrigation with 3% NaOCl for 1 min, etch and rinse procedure and composite restorations. In Groups 4 and 5, dentin biomodification was done prior to composite restorations. Teeth were subjected to fracture resistance tests. Statistical analysis was carried out employing analysis of variance (ANOVA) and Tukey’s post hoc tests ( p < .05). IES group demonstrated the highest fracture resistance, with a significant difference statistically ( p < .05) when compared with the DES groups. DES modified with GSE resulted in significantly superior fracture resistance compared to DES only, but no statistical difference was present between the CHX and grape seed-treated DES groups. DES with the use of dentin biomodifiers such as 5% GSE and 2% CHX increased the fracture resistance of root canal-treated teeth compared to DES only.
{"title":"Effect of Delayed Endodontic Sealing with Dentin Biomodification on Fracture Resistance of Endodontically Treated Teeth","authors":"Javed Ahmad, G. Sajjan, Durga Bhavani Panithini, Madhu Varma, Kalyan Satish R, K. D. Prasad","doi":"10.1177/23202068231193606","DOIUrl":"https://doi.org/10.1177/23202068231193606","url":null,"abstract":"Endodontically treated teeth display altered tooth structure pertaining to various chemical irrigants and intracanal medicaments. To prevent the compromised adhesive bond, dentin biomodification is indicated. This study was designed to evaluate the influence of dentin biomodification on the fracture resistance of root canal-treated teeth following Delayed Endodontic Sealing (DES). In 50 maxillary central incisors, Class III cavities along with access cavities were prepared. The samples were randomly divided into five groups. Group 1: Intact teeth ( N = 10), Group 2: Immediate Endodontic Sealing (IES) ( N = 10); Group 3: DES after irrigation with 3% NaOCl ( N = 10); Group 4: DES with 2% chlorhexidine (CHX) as a biomodifier ( N = 10) and Group 5: DES with 5% grape seed extract (GSE) as a biomodifier ( N = 10). In Group 2 samples, composite restorations were done prior to irrigation with 3% sodium hypochlorite (NaOCl). Group 3 samples received root canal irrigation with 3% NaOCl for 1 min, etch and rinse procedure and composite restorations. In Groups 4 and 5, dentin biomodification was done prior to composite restorations. Teeth were subjected to fracture resistance tests. Statistical analysis was carried out employing analysis of variance (ANOVA) and Tukey’s post hoc tests ( p < .05). IES group demonstrated the highest fracture resistance, with a significant difference statistically ( p < .05) when compared with the DES groups. DES modified with GSE resulted in significantly superior fracture resistance compared to DES only, but no statistical difference was present between the CHX and grape seed-treated DES groups. DES with the use of dentin biomodifiers such as 5% GSE and 2% CHX increased the fracture resistance of root canal-treated teeth compared to DES only.","PeriodicalId":43017,"journal":{"name":"Journal of Advanced Oral Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81029524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-31DOI: 10.1177/23202068231193772
Sreejeeta Dey, S. Deshmukh, U. Maheshwari, Dheeraj, Sinchan
Effective toothbrushing is the most simple way to maintain a child’s oral hygiene for a cavity-free mouth. Yet, most children find it an uninteresting task and they fail to understand its scientific basis. Augmented reality (A-R)-assisted toothbrushes for pediatric population are commercially available to make toothbrushing interactive, interesting, and educative for the child, aided by gamification providing an interactive videogame platform between the real and the virtual world. The aim of the study was to evaluate the efficacy of A-R-assisted brushing experience of children with respect to fluorescence imaging data and plaque Streptococcus mutans count at clinical and microbiological levels, respectively. A total of 32 children in the age group of 6-8 years were included and allocated in two study groups (A-R-assisted toothbrushing and manual toothbrushing). Fluorescence-based lesion area scoring was done using FC, Duerr Dental, Vistaproof, Germany. Microbiological analysis of plaque Streptococcus mutans was done to evaluate change in bacterial count. The parameters were recorded again after two weeks. Pre- and post-intervention scores were subjected to statistical analysis. Significantly higher reduction of fluorescent scores and mean bacterial count were found in A-R-assisted tooth-brushing group when compared to that of manual toothbrushing. Based on the findings of the study, A-R-assisted toothbrushing proves to be an effective tool for motivating and maintaining oral hygiene among children and efforts should be made in incorporating this practice in daily domestic healthcare.
{"title":"Fluorescence-based Evaluation of the Efficacy of Augmented Reality-assisted Toothbrush on Oral Hygiene Practices Among 6–8 Years Old Children","authors":"Sreejeeta Dey, S. Deshmukh, U. Maheshwari, Dheeraj, Sinchan","doi":"10.1177/23202068231193772","DOIUrl":"https://doi.org/10.1177/23202068231193772","url":null,"abstract":"Effective toothbrushing is the most simple way to maintain a child’s oral hygiene for a cavity-free mouth. Yet, most children find it an uninteresting task and they fail to understand its scientific basis. Augmented reality (A-R)-assisted toothbrushes for pediatric population are commercially available to make toothbrushing interactive, interesting, and educative for the child, aided by gamification providing an interactive videogame platform between the real and the virtual world. The aim of the study was to evaluate the efficacy of A-R-assisted brushing experience of children with respect to fluorescence imaging data and plaque Streptococcus mutans count at clinical and microbiological levels, respectively. A total of 32 children in the age group of 6-8 years were included and allocated in two study groups (A-R-assisted toothbrushing and manual toothbrushing). Fluorescence-based lesion area scoring was done using FC, Duerr Dental, Vistaproof, Germany. Microbiological analysis of plaque Streptococcus mutans was done to evaluate change in bacterial count. The parameters were recorded again after two weeks. Pre- and post-intervention scores were subjected to statistical analysis. Significantly higher reduction of fluorescent scores and mean bacterial count were found in A-R-assisted tooth-brushing group when compared to that of manual toothbrushing. Based on the findings of the study, A-R-assisted toothbrushing proves to be an effective tool for motivating and maintaining oral hygiene among children and efforts should be made in incorporating this practice in daily domestic healthcare.","PeriodicalId":43017,"journal":{"name":"Journal of Advanced Oral Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85366509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-13DOI: 10.1177/23202068231190199
Preethi Rajamanickam, K. Sundari
For its synergistic effects in producing skeletal changes as well as to lessen the proclination of the lower incisors, which is a common negative result of mandibular advancement, fixed functional appliances with skeletal anchorage have recently been used. Objective was to evaluate the skeletal and dentoalveolar effects with fixed functional appliances with and without skeletal anchorage. Electronic database search and manual search were performed up to 2021, April in four databases namely The Cochrane Library, PubMed, Lilac, and Google Scholar. RCTs that employed the use of fixed functional appliances in Class II malocclusion with and without skeletal anchoring were collected. Two co-authors independently extracted the data, and a pre-designed template was followed during the data extraction process. Data including inclusion and exclusion criteria; study design, the year of publication; age and gender of the patients; type of fixed functional device; stage of skeletal maturation; size and site of mini-implant or miniplate placement, amount of force applied in grams or Newtons; method of study outcome assessment (2D or 3D); and follow up were collected. The skeletal and dentoalveolar parameters were extracted. The risk of bias was evaluated, and the SMD and 95% confidence intervals (CIs) were also calculated. Four RCTs were evaluated for qualitative and quantitative analysis. The review involved data of 179 Class II individuals. The results of a random-effects meta-analysis showed that the SNB differed significantly from the control group (SMD = 0.50 (95% CI –1.55 to –0.10)). No significant differences noted between the two groups in terms of lower incisor inclination and mandibular length changes [SMD = –0.04 (95% CI −2.06 to 1.98) and –1.33 (95% CI −3.28 to 0.62), respectively]. The studies under this were not able to provide enough data to draw any conclusions about the effects of using skeletal anchorage with FFA. According to the evidence that is currently available, using FFA coupled with skeletal anchorage does not appear to have any superior skeletal effects than those without skeletal anchorage.
由于其在产生骨骼变化方面的协同作用，以及减少下门牙的下垂，这是下颌向前发展的常见负面结果，最近使用了带有骨骼锚固的固定功能矫治器。目的是评价带和不带骨支抗的固定功能矫治器对骨骼和牙槽骨的影响。截至2021年4月，在The Cochrane Library、PubMed、Lilac和Google Scholar四个数据库中进行了电子检索和人工检索。收集了使用固定功能矫治器治疗II类错牙合的随机对照试验。两位共同作者独立提取数据，在数据提取过程中遵循预先设计的模板。数据包括纳入和排除标准;研究设计，出版年份;患者年龄、性别;固定功能装置类型;骨骼成熟阶段;微型植入物或微型钢板的大小和位置，施加的力的大小(以克或牛顿为单位);研究结果评估方法(2D或3D);并收集了随访数据。提取骨骼和牙槽参数。评估偏倚风险，并计算SMD和95%置信区间(ci)。对4个随机对照试验进行定性和定量分析。本综述涉及179例II类个体的数据。随机效应荟萃分析的结果显示，SNB与对照组有显著差异(SMD = 0.50 (95% CI -1.55 ~ -0.10))。两组在下切牙倾斜度和下颌长度变化方面无显著差异[SMD分别= -0.04 (95% CI - 2.06至1.98)和-1.33 (95% CI - 3.28至0.62)]。这项研究没有提供足够的数据来得出关于骨骼锚具与FFA的效果的任何结论。根据目前可获得的证据，使用FFA联合骨骼锚固剂并不比不使用骨骼锚固剂有任何优越的骨骼效果。
{"title":"Fixed Functional Appliance Therapy With and Without Skeletal Anchorage in Class II Malocclusion: A Systematic Review of Randomized Controlled Trials","authors":"Preethi Rajamanickam, K. Sundari","doi":"10.1177/23202068231190199","DOIUrl":"https://doi.org/10.1177/23202068231190199","url":null,"abstract":"For its synergistic effects in producing skeletal changes as well as to lessen the proclination of the lower incisors, which is a common negative result of mandibular advancement, fixed functional appliances with skeletal anchorage have recently been used. Objective was to evaluate the skeletal and dentoalveolar effects with fixed functional appliances with and without skeletal anchorage. Electronic database search and manual search were performed up to 2021, April in four databases namely The Cochrane Library, PubMed, Lilac, and Google Scholar. RCTs that employed the use of fixed functional appliances in Class II malocclusion with and without skeletal anchoring were collected. Two co-authors independently extracted the data, and a pre-designed template was followed during the data extraction process. Data including inclusion and exclusion criteria; study design, the year of publication; age and gender of the patients; type of fixed functional device; stage of skeletal maturation; size and site of mini-implant or miniplate placement, amount of force applied in grams or Newtons; method of study outcome assessment (2D or 3D); and follow up were collected. The skeletal and dentoalveolar parameters were extracted. The risk of bias was evaluated, and the SMD and 95% confidence intervals (CIs) were also calculated. Four RCTs were evaluated for qualitative and quantitative analysis. The review involved data of 179 Class II individuals. The results of a random-effects meta-analysis showed that the SNB differed significantly from the control group (SMD = 0.50 (95% CI –1.55 to –0.10)). No significant differences noted between the two groups in terms of lower incisor inclination and mandibular length changes [SMD = –0.04 (95% CI −2.06 to 1.98) and –1.33 (95% CI −3.28 to 0.62), respectively]. The studies under this were not able to provide enough data to draw any conclusions about the effects of using skeletal anchorage with FFA. According to the evidence that is currently available, using FFA coupled with skeletal anchorage does not appear to have any superior skeletal effects than those without skeletal anchorage.","PeriodicalId":43017,"journal":{"name":"Journal of Advanced Oral Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76442727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-11DOI: 10.1177/23202068231177239
F. Farzanegan, Ghazal Ghasemi Nour, M. Mobarhan, Abdolrasoul Rangrazi
One of the problems that orthodontists commonly face is the prolonged duration of the treatment. Therefore, it is important to find an effective method to increase the rate of orthodontic tooth movement (OTM). This study aimed to evaluate the effectiveness of oral administration of vitamin D3 on OTM rates in humans. In this randomized clinical trial study, we selected 29 healthy women aged 18–25 years who sought orthodontic treatment and required bilateral maxillary first premolar extraction. Participants were tested to measure the blood levels of vitamin D3 and, based on the outcomes, were divided into three groups: control (without vitamin D3 deficiency; N = 10), placebo ( N = 9), and experiment ( N = 10), both with vitamin D3 deficiency. Subjects of the last two groups, who were randomly assigned, received 50,000 IU (International Unit) vitamin D3 pearls (Dana Pharmaceutical Company, Tabriz, Iran) or a placebo every 2 weeks for 2 months. Inclusion criteria were patients requiring bilateral extraction of the first premolar in the maxilla. The canines were retracted by nickel-titanium (NiTi) coil springs into the extraction sites. At the beginning, after 1 and 2 months, the distance between canine and lateral teeth on both sides was measured to calculate OTM. In the first month ( t (1–2)), the mean values of OTM in the placebo group were higher than the other groups. However, during the second month ( t (2–3)) and overall ( t (1–3)), the experiment group showed a higher OTM. The experiment and control groups were statistically different in all three time periods ( P-value < .05). The difference between the experiment and placebo groups was only significant in t (2–3) ( P-value < .05). Whereas the placebo and control groups showed a significant difference in t (1–2) ( P-value < .05). Vitamin D3 deficiency seems to increase OTM. Receiving oral supplements of vitamin D3 may not have much effect on increasing the level of vitamin D3. The lowest OTM rate was observed in the control group.
{"title":"Evaluation of the Effect of Oral Vitamin D3 Supplement on Orthodontic Tooth Movement: A Randomized Clinical Trial Study","authors":"F. Farzanegan, Ghazal Ghasemi Nour, M. Mobarhan, Abdolrasoul Rangrazi","doi":"10.1177/23202068231177239","DOIUrl":"https://doi.org/10.1177/23202068231177239","url":null,"abstract":"One of the problems that orthodontists commonly face is the prolonged duration of the treatment. Therefore, it is important to find an effective method to increase the rate of orthodontic tooth movement (OTM). This study aimed to evaluate the effectiveness of oral administration of vitamin D3 on OTM rates in humans. In this randomized clinical trial study, we selected 29 healthy women aged 18–25 years who sought orthodontic treatment and required bilateral maxillary first premolar extraction. Participants were tested to measure the blood levels of vitamin D3 and, based on the outcomes, were divided into three groups: control (without vitamin D3 deficiency; N = 10), placebo ( N = 9), and experiment ( N = 10), both with vitamin D3 deficiency. Subjects of the last two groups, who were randomly assigned, received 50,000 IU (International Unit) vitamin D3 pearls (Dana Pharmaceutical Company, Tabriz, Iran) or a placebo every 2 weeks for 2 months. Inclusion criteria were patients requiring bilateral extraction of the first premolar in the maxilla. The canines were retracted by nickel-titanium (NiTi) coil springs into the extraction sites. At the beginning, after 1 and 2 months, the distance between canine and lateral teeth on both sides was measured to calculate OTM. In the first month ( t (1–2)), the mean values of OTM in the placebo group were higher than the other groups. However, during the second month ( t (2–3)) and overall ( t (1–3)), the experiment group showed a higher OTM. The experiment and control groups were statistically different in all three time periods ( P-value < .05). The difference between the experiment and placebo groups was only significant in t (2–3) ( P-value < .05). Whereas the placebo and control groups showed a significant difference in t (1–2) ( P-value < .05). Vitamin D3 deficiency seems to increase OTM. Receiving oral supplements of vitamin D3 may not have much effect on increasing the level of vitamin D3. The lowest OTM rate was observed in the control group.","PeriodicalId":43017,"journal":{"name":"Journal of Advanced Oral Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76752453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-21DOI: 10.1177/23202068231174808
Akanksha Shinde, Nilesh Bulbule, Varun Bhatt, B. Gayathri, Amit K Jagtap
This in vitro study compared the fatigue resistance of two polymeric materials (Nylon and Polytetrafluoroethylene (PTFE)) used as retentive attachments in implant-retained overdentures after immersion in denture cleansing solution. A total of 24 samples (N=24), of which 12 capsule-shaped samples of commercially available nylon material from ADIN dental implants, India, and similar sized and shaped 12 PTFE (medical grade) capsules custom fabricated from AAA Industries, Mumbai was obtained. Six samples of each material were immersed in distilled water and six samples in Clinsodent denture cleanser, simulating an 8–h daily immersion of the denture for a period of 2 years. After completion of the immersion protocol, samples were subjected to 2900 fatigue cycles using the Universal Testing Machine (UTM), simulating 4 cycles per day of removal and insertion of the overdenture for a duration of 2 years. Before and after immersion, the wear of the samples was assessed for internal and external diameter changes using the Sipcon Inspection System. The statistical analysis of the obtained results was tested by applying the paired-t test, Fisher analysis of variance, and Tukey’s honest significant difference test, with a probability value less than 0.05 used as statistically significant. Statistically significant differences were observed after immersion in denture cleanser for nylon and PTFE. The greatest fatigue for ID, IHL, and IVL was demonstrated in nylon immersed in Clinsodent at p = .000. ED and EHL of PTFE in distilled water showed greater deformation than others ( p = .000). PTFE attachments have shown better fatigue resistance after immersion in Clinsodent denture cleanser. Nylon material immersed in distilled water as well as in Clinsodent cleanser showed greater deformation after fatigue cycles.
{"title":"Fatigue Resistance of Two Different Materials Used as Retentive Attachments in Implant Supported Overdenture after Immersion in Denture Cleansing Solution: An In Vitro Comparative Study","authors":"Akanksha Shinde, Nilesh Bulbule, Varun Bhatt, B. Gayathri, Amit K Jagtap","doi":"10.1177/23202068231174808","DOIUrl":"https://doi.org/10.1177/23202068231174808","url":null,"abstract":"This in vitro study compared the fatigue resistance of two polymeric materials (Nylon and Polytetrafluoroethylene (PTFE)) used as retentive attachments in implant-retained overdentures after immersion in denture cleansing solution. A total of 24 samples (N=24), of which 12 capsule-shaped samples of commercially available nylon material from ADIN dental implants, India, and similar sized and shaped 12 PTFE (medical grade) capsules custom fabricated from AAA Industries, Mumbai was obtained. Six samples of each material were immersed in distilled water and six samples in Clinsodent denture cleanser, simulating an 8–h daily immersion of the denture for a period of 2 years. After completion of the immersion protocol, samples were subjected to 2900 fatigue cycles using the Universal Testing Machine (UTM), simulating 4 cycles per day of removal and insertion of the overdenture for a duration of 2 years. Before and after immersion, the wear of the samples was assessed for internal and external diameter changes using the Sipcon Inspection System. The statistical analysis of the obtained results was tested by applying the paired-t test, Fisher analysis of variance, and Tukey’s honest significant difference test, with a probability value less than 0.05 used as statistically significant. Statistically significant differences were observed after immersion in denture cleanser for nylon and PTFE. The greatest fatigue for ID, IHL, and IVL was demonstrated in nylon immersed in Clinsodent at p = .000. ED and EHL of PTFE in distilled water showed greater deformation than others ( p = .000). PTFE attachments have shown better fatigue resistance after immersion in Clinsodent denture cleanser. Nylon material immersed in distilled water as well as in Clinsodent cleanser showed greater deformation after fatigue cycles.","PeriodicalId":43017,"journal":{"name":"Journal of Advanced Oral Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83823031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-21DOI: 10.1177/23202068231171506
Lillie Elizabeth Abanto-Silva, Ana Cristina López-Torres, M. Garcés-Elías, R. León-Manco
To determine the association between chronic diseases (CD) and the need for dental treatment in patients of the stomatology of special patients service (SSPS) of the Teaching Dental Center (TDC) of Universidad Peruana Cayetano Heredia (UPCH) in Lima-Peru from 2016 to 2019. A cross-sectional study with a total population of 2024 digital medical records of individuals over 18 years old. A dependent variable was need for dental treatment, so an instrument to assess it was created; additionally, the presence of CD was evaluated. Other covariates considered were pharmacological treatment, last dental visit, provenance, age group, and sex. Statistical analyses were performed, including a bivariate analysis using the Chi-square test. Finally, a Poisson linear regression was performed to determine crude and adjusted prevalence ratios (aPR) with the variables showing associations, with a 95% confidence level (95%CI) and a p < .05 value. The need for low-complexity dental treatment was present in 2.62% ( n = 52) of patients, moderate complexity in 27.21% ( n = 541) of patients, and high complexity in 70.17% ( n = 1395) of patients. In relation to CD, 30.58% ( n = 608) had one, 31.39% ( n = 624) had two, and 38.03% ( n = 756) had three or more. In the multivariate analysis, the presence of three to more CD and the need for high-complexity vs. low-complexity treatment, an aPR of 1.02 (95%CI): 1.01–1.04; p = .019) was obtained. There is a positive association between the presence of three or more CD and the need for high complexity dental treatment compared to low-complexity dental treatment, adjusted for use of pharmacological treatment and age.
{"title":"Association Between Chronic Diseases and Need for Dental Treatment in a Stomatology of Special Patients Service","authors":"Lillie Elizabeth Abanto-Silva, Ana Cristina López-Torres, M. Garcés-Elías, R. León-Manco","doi":"10.1177/23202068231171506","DOIUrl":"https://doi.org/10.1177/23202068231171506","url":null,"abstract":"To determine the association between chronic diseases (CD) and the need for dental treatment in patients of the stomatology of special patients service (SSPS) of the Teaching Dental Center (TDC) of Universidad Peruana Cayetano Heredia (UPCH) in Lima-Peru from 2016 to 2019. A cross-sectional study with a total population of 2024 digital medical records of individuals over 18 years old. A dependent variable was need for dental treatment, so an instrument to assess it was created; additionally, the presence of CD was evaluated. Other covariates considered were pharmacological treatment, last dental visit, provenance, age group, and sex. Statistical analyses were performed, including a bivariate analysis using the Chi-square test. Finally, a Poisson linear regression was performed to determine crude and adjusted prevalence ratios (aPR) with the variables showing associations, with a 95% confidence level (95%CI) and a p < .05 value. The need for low-complexity dental treatment was present in 2.62% ( n = 52) of patients, moderate complexity in 27.21% ( n = 541) of patients, and high complexity in 70.17% ( n = 1395) of patients. In relation to CD, 30.58% ( n = 608) had one, 31.39% ( n = 624) had two, and 38.03% ( n = 756) had three or more. In the multivariate analysis, the presence of three to more CD and the need for high-complexity vs. low-complexity treatment, an aPR of 1.02 (95%CI): 1.01–1.04; p = .019) was obtained. There is a positive association between the presence of three or more CD and the need for high complexity dental treatment compared to low-complexity dental treatment, adjusted for use of pharmacological treatment and age.","PeriodicalId":43017,"journal":{"name":"Journal of Advanced Oral Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72930357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-27DOI: 10.1177/23202068231166499
Mahesh V. Dadpe, Nikita A. Chordiya, Y. Kale, Prasanna T. Dahake, Shrikant B. Kendre, Shrawani S. Mankar
Aim: A space deficiency in the dental arch may result from the early loss of a second deciduous molar before the eruption of the first permanent molar. In this circumstance, the Distal Shoe Space Maintainer (DSSM) is recommended to prevent space loss. We aimed to evaluate the effectiveness and safety of this device. Materials and Methods: PUBMED, Cochrane libraries, Google scholar, Ebsco, and Science Gov. were all thoroughly searched. The effectiveness of DSSM as measured by patient tolerance and gingival response to DSSM was our main outcome goal. Also, we evaluated each study’s quality and design. Results: Eleven publications that fit the criteria for inclusion were examined after duplicates were removed. These papers were eventually chosen and thoroughly examined. The studies provided insufficient details regarding the efficacy of space maintenance or gingival response to the DSSM. Conclusion: The main concern is to provide maximum benefit to the patient with minimum discomfort, maximum effectiveness, more cooperation and less chair-side time which can be achieved by the modified distal shoe appliance when compared with the conventional, as it was more stable and required less chair-side time. Though the appliances were designed keeping all the basic requirements in mind, it is firmly recommended to assess more patient-centered outcomes of DSSMs.
{"title":"Evaluation of Efficiency of Distal Shoe Space Maintainer: A Systematic Review","authors":"Mahesh V. Dadpe, Nikita A. Chordiya, Y. Kale, Prasanna T. Dahake, Shrikant B. Kendre, Shrawani S. Mankar","doi":"10.1177/23202068231166499","DOIUrl":"https://doi.org/10.1177/23202068231166499","url":null,"abstract":"Aim: A space deficiency in the dental arch may result from the early loss of a second deciduous molar before the eruption of the first permanent molar. In this circumstance, the Distal Shoe Space Maintainer (DSSM) is recommended to prevent space loss. We aimed to evaluate the effectiveness and safety of this device. Materials and Methods: PUBMED, Cochrane libraries, Google scholar, Ebsco, and Science Gov. were all thoroughly searched. The effectiveness of DSSM as measured by patient tolerance and gingival response to DSSM was our main outcome goal. Also, we evaluated each study’s quality and design. Results: Eleven publications that fit the criteria for inclusion were examined after duplicates were removed. These papers were eventually chosen and thoroughly examined. The studies provided insufficient details regarding the efficacy of space maintenance or gingival response to the DSSM. Conclusion: The main concern is to provide maximum benefit to the patient with minimum discomfort, maximum effectiveness, more cooperation and less chair-side time which can be achieved by the modified distal shoe appliance when compared with the conventional, as it was more stable and required less chair-side time. Though the appliances were designed keeping all the basic requirements in mind, it is firmly recommended to assess more patient-centered outcomes of DSSMs.","PeriodicalId":43017,"journal":{"name":"Journal of Advanced Oral Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82854342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-17DOI: 10.1177/23202068231166507
Preethi Rajamanickam, N. Ramasamy
Aim: Accumulation of plaque during orthodontic treatment makes oral prophylaxis a regular necessity. The use of esthetic brackets has gained popularity, it becomes necessary to assess the consequences of ultrasonic instrumentation during oral prophylaxis on ceramic bracket’s shear bond strength (SBS). Materials and Methods: Fifty-four premolar teeth which were extracted due to therapeutic reasons were divided into six groups with each group containing nine teeth each. Ceramic brackets were bonded onto the labial surfaces using two different adhesive systems (Ormco Enlight and Transbond) and were subjected to ultrasonic scaling at different scaler tip angulations. The samples were then rendered a debonding force in a Universal testing machine and the bond strengths were assessed. Results: In terms of angulation of ultrasonic instrumentation, among the groups bonded with the Ormco Enlight, the 45° angulation group had statistically significant higher bond strength values compared to the 0° angulation group. Among the transbond groups, there was no statistically significant difference in the bond strengths even though the 45° angulation group had slightly higher bond strength value than the 0° angulation group. Conclusion: Supragingival scaling around the bracket base at 0° around the ceramic brackets for 1 min resulted in the reduction of SBS. Therefore, the clinicians should be cautious during plaque removal, avoid performing extended ultrasonic instrumentation at the bracket base, especially at 0° angulation.
{"title":"Effects of Ultrasonic Instrumentation on the Shear Bond Strength of Ceramic Brackets: An In Vitro Study","authors":"Preethi Rajamanickam, N. Ramasamy","doi":"10.1177/23202068231166507","DOIUrl":"https://doi.org/10.1177/23202068231166507","url":null,"abstract":"Aim: Accumulation of plaque during orthodontic treatment makes oral prophylaxis a regular necessity. The use of esthetic brackets has gained popularity, it becomes necessary to assess the consequences of ultrasonic instrumentation during oral prophylaxis on ceramic bracket’s shear bond strength (SBS). Materials and Methods: Fifty-four premolar teeth which were extracted due to therapeutic reasons were divided into six groups with each group containing nine teeth each. Ceramic brackets were bonded onto the labial surfaces using two different adhesive systems (Ormco Enlight and Transbond) and were subjected to ultrasonic scaling at different scaler tip angulations. The samples were then rendered a debonding force in a Universal testing machine and the bond strengths were assessed. Results: In terms of angulation of ultrasonic instrumentation, among the groups bonded with the Ormco Enlight, the 45° angulation group had statistically significant higher bond strength values compared to the 0° angulation group. Among the transbond groups, there was no statistically significant difference in the bond strengths even though the 45° angulation group had slightly higher bond strength value than the 0° angulation group. Conclusion: Supragingival scaling around the bracket base at 0° around the ceramic brackets for 1 min resulted in the reduction of SBS. Therefore, the clinicians should be cautious during plaque removal, avoid performing extended ultrasonic instrumentation at the bracket base, especially at 0° angulation.","PeriodicalId":43017,"journal":{"name":"Journal of Advanced Oral Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74414181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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