Pub Date : 2011-03-07DOI: 10.1109/BIOWIRELESS.2011.5724343
K. Eom, Hiroyuki Arai
This paper presents a novel concept data collecting device for body-centric wireless communications, smart robe or blanket. It couples to sensor units on human body wirelessly by just putting on the human body. It is consisting of textile-based free access mat. The free access mat is a thin sheet-shaped waveguide which wireless devices can couple to at an arbitrary position on it. We investigate the transmission characteristics depending on materials, folding or bending, the presence of the human body.
{"title":"Smart blanket: Flexible and easy to couple waveguide","authors":"K. Eom, Hiroyuki Arai","doi":"10.1109/BIOWIRELESS.2011.5724343","DOIUrl":"https://doi.org/10.1109/BIOWIRELESS.2011.5724343","url":null,"abstract":"This paper presents a novel concept data collecting device for body-centric wireless communications, smart robe or blanket. It couples to sensor units on human body wirelessly by just putting on the human body. It is consisting of textile-based free access mat. The free access mat is a thin sheet-shaped waveguide which wireless devices can couple to at an arbitrary position on it. We investigate the transmission characteristics depending on materials, folding or bending, the presence of the human body.","PeriodicalId":430449,"journal":{"name":"2011 IEEE Topical Conference on Biomedical Wireless Technologies, Networks, and Sensing Systems","volume":"356 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116132861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-03-07DOI: 10.1109/BIOWIRELESS.2011.5724351
K. Grenier, D. Dubuc, M. Poupot, J. Fournié
This publication deals with the determination of the microwave dielectric signatures of tumorous B-lymphoma cells (NHL) up to 40 GHz. It is demonstrated that in-liquid microwave detection permits to warrant cells' living without deterioration of the analysis capabilities. The key role of the microwave absorption parameter for cells detection is moreover pointed out. The richness of the microwave signature combined with the non invasivity of such a technique provide to biologists new way to investigate cells, to identify tumorous vs non tumorous ones.
{"title":"Microwave signatures of alive B-lymphoma cells suspensions","authors":"K. Grenier, D. Dubuc, M. Poupot, J. Fournié","doi":"10.1109/BIOWIRELESS.2011.5724351","DOIUrl":"https://doi.org/10.1109/BIOWIRELESS.2011.5724351","url":null,"abstract":"This publication deals with the determination of the microwave dielectric signatures of tumorous B-lymphoma cells (NHL) up to 40 GHz. It is demonstrated that in-liquid microwave detection permits to warrant cells' living without deterioration of the analysis capabilities. The key role of the microwave absorption parameter for cells detection is moreover pointed out. The richness of the microwave signature combined with the non invasivity of such a technique provide to biologists new way to investigate cells, to identify tumorous vs non tumorous ones.","PeriodicalId":430449,"journal":{"name":"2011 IEEE Topical Conference on Biomedical Wireless Technologies, Networks, and Sensing Systems","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122065965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-03-07DOI: 10.1109/BIOWIRELESS.2011.5724352
M. Kuhn, M. Mahfouz, J. Turnmire, Yazhou Wang, A. Fathy
Ultra wideband (UWB) wireless systems have many advantages in indoor environments with dense multipath. UWB positioning systems are increasingly used in indoor environments to track and locate important assets. Many applications exist in medicine for UWB positioning which includes tracking personnel, assets, and even surgical navigation. We have designed a UWB positioning system with millimeter range accuracy with potential use in surgical navigation. This paper outlines a multi-tag access scheme for our UWB positioning system which integrates a 2.4 GHz physical layer to allow simultaneous tracking of up to 30 UWB tags. A static experiment was performed with two UWB tags while switching between the tags at 20 Hz. Millimeter accuracy was achieved even when tracking two tags. A 10% system latency was experienced when adding the multi-tag overhead, although a 744 Hz system update rate was still achieved. Asynchronous communication between the FPGA and microcontroller at the main control station ensured correct synchronization of the 3-D positioning data and corresponding tag ID. Future work includes a full dynamic experiment with simultaneous tracking of 5-10 tags.
{"title":"A multi-tag access scheme for indoor UWB localization systems used in medical environments","authors":"M. Kuhn, M. Mahfouz, J. Turnmire, Yazhou Wang, A. Fathy","doi":"10.1109/BIOWIRELESS.2011.5724352","DOIUrl":"https://doi.org/10.1109/BIOWIRELESS.2011.5724352","url":null,"abstract":"Ultra wideband (UWB) wireless systems have many advantages in indoor environments with dense multipath. UWB positioning systems are increasingly used in indoor environments to track and locate important assets. Many applications exist in medicine for UWB positioning which includes tracking personnel, assets, and even surgical navigation. We have designed a UWB positioning system with millimeter range accuracy with potential use in surgical navigation. This paper outlines a multi-tag access scheme for our UWB positioning system which integrates a 2.4 GHz physical layer to allow simultaneous tracking of up to 30 UWB tags. A static experiment was performed with two UWB tags while switching between the tags at 20 Hz. Millimeter accuracy was achieved even when tracking two tags. A 10% system latency was experienced when adding the multi-tag overhead, although a 744 Hz system update rate was still achieved. Asynchronous communication between the FPGA and microcontroller at the main control station ensured correct synchronization of the 3-D positioning data and corresponding tag ID. Future work includes a full dynamic experiment with simultaneous tracking of 5-10 tags.","PeriodicalId":430449,"journal":{"name":"2011 IEEE Topical Conference on Biomedical Wireless Technologies, Networks, and Sensing Systems","volume":"96 12","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120867025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-03-07DOI: 10.1109/BIOWIRELESS.2011.5724337
R. Bashirullah
Neural interfaces convert brain signals into outputs that infer brain intentional states. As a communication channel it can be used to implement brain computer interfaces (BCIs) to aid subjects with severe motor disabilities. The realization of this emerging paradigm of neural prosthetics requires extremely low power, small, low noise, highly parallel and distributed signal acquisition hardware platforms with on-chip signal processing and energy efficient wireless data communication. This paper presents a brief overview of the hardware challenges and considerations in BCI systems.
{"title":"Low power microsystems for brain computer interfaces","authors":"R. Bashirullah","doi":"10.1109/BIOWIRELESS.2011.5724337","DOIUrl":"https://doi.org/10.1109/BIOWIRELESS.2011.5724337","url":null,"abstract":"Neural interfaces convert brain signals into outputs that infer brain intentional states. As a communication channel it can be used to implement brain computer interfaces (BCIs) to aid subjects with severe motor disabilities. The realization of this emerging paradigm of neural prosthetics requires extremely low power, small, low noise, highly parallel and distributed signal acquisition hardware platforms with on-chip signal processing and energy efficient wireless data communication. This paper presents a brief overview of the hardware challenges and considerations in BCI systems.","PeriodicalId":430449,"journal":{"name":"2011 IEEE Topical Conference on Biomedical Wireless Technologies, Networks, and Sensing Systems","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125901840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-03-07DOI: 10.1109/BIOWIRELESS.2011.5724341
M. Mahfouz, M. Kuhn
The prevalence of UWB has greatly increased in recent years for numerous applications in dense multipath indoor environments. We have measured and modeled the ultra-wideband (UWB) channel environment found in the operating room which can be used to examine its effects on the performance of UWB positioning and communications systems. Frequency and time domain measurement data obtained in the operating room in both live (during orthopedic surgeries) and non-live scenarios was fit to the IEEE 802.15.4a channel model. Simulation data was then obtained through the IEEE 802.15.4a channel model for characterizing the operating room environment. Electromagnetic interference was also measured in the operating room. Even in the dense multipath environment found in the operating room, UWB shows strong potential for multiple applications including wireless tracking for surgical navigation, incorporation into low power ex vivo and in vivo bio-sensors, and high data rate wireless telemetry of critical bio-signals including ECG, EMG, blood pressure, and body temperature.
{"title":"UWB channel measurements and modeling for positioning and communications systems in the operating room","authors":"M. Mahfouz, M. Kuhn","doi":"10.1109/BIOWIRELESS.2011.5724341","DOIUrl":"https://doi.org/10.1109/BIOWIRELESS.2011.5724341","url":null,"abstract":"The prevalence of UWB has greatly increased in recent years for numerous applications in dense multipath indoor environments. We have measured and modeled the ultra-wideband (UWB) channel environment found in the operating room which can be used to examine its effects on the performance of UWB positioning and communications systems. Frequency and time domain measurement data obtained in the operating room in both live (during orthopedic surgeries) and non-live scenarios was fit to the IEEE 802.15.4a channel model. Simulation data was then obtained through the IEEE 802.15.4a channel model for characterizing the operating room environment. Electromagnetic interference was also measured in the operating room. Even in the dense multipath environment found in the operating room, UWB shows strong potential for multiple applications including wireless tracking for surgical navigation, incorporation into low power ex vivo and in vivo bio-sensors, and high data rate wireless telemetry of critical bio-signals including ECG, EMG, blood pressure, and body temperature.","PeriodicalId":430449,"journal":{"name":"2011 IEEE Topical Conference on Biomedical Wireless Technologies, Networks, and Sensing Systems","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115663368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-03-07DOI: 10.1109/BIOWIRELESS.2011.5724361
R. Wasielewski
Wireless technologies can be used as diagnostic tools, which are of prime interest in medical applications. For example, in orthopedics an array of inertial measurement units (IMUs) combined with ultrasound sensing provides a radiation free method to monitor in-vivo motion (e.g. bones in the knee); or a network of sensors to detect abnormal motions or vibrations for remote patient monitoring (e.g. unattended monitoring of elderly patients or epileptic patients). Miniaturization of low-powered medical sensors, such as oximeter, EEG, ECG, and EMG, combined with high bandwidth wireless communication (e.g. ultra wideband) enable WSNs to be used for patient monitoring over extended periods of time. These data can be transmitted wirelessly and stored on the patient's medical record to provide in-depth record tracking for further diagnosis. There are also intraoperative applications for wireless sensor networks (WSNs). Surgical instruments embedded with Micro-Electromechanical System (MEMS) sensors provide immediate feedback about a patient's condition to doctors during surgery including temperature, pressure, strain, or biochemical reactions. Finally, ultra-wideband combined with WSNs provides a robust platform for developing WSNs which includes accurate 3-D positioning and high data rate or low data rate digital communication with optimized performance for indoor environments which contain high amounts of multipath (e.g. metallic) interference.
{"title":"Wireless technologies for the orthopaedics: Diagnostics and surgical applications","authors":"R. Wasielewski","doi":"10.1109/BIOWIRELESS.2011.5724361","DOIUrl":"https://doi.org/10.1109/BIOWIRELESS.2011.5724361","url":null,"abstract":"Wireless technologies can be used as diagnostic tools, which are of prime interest in medical applications. For example, in orthopedics an array of inertial measurement units (IMUs) combined with ultrasound sensing provides a radiation free method to monitor in-vivo motion (e.g. bones in the knee); or a network of sensors to detect abnormal motions or vibrations for remote patient monitoring (e.g. unattended monitoring of elderly patients or epileptic patients). Miniaturization of low-powered medical sensors, such as oximeter, EEG, ECG, and EMG, combined with high bandwidth wireless communication (e.g. ultra wideband) enable WSNs to be used for patient monitoring over extended periods of time. These data can be transmitted wirelessly and stored on the patient's medical record to provide in-depth record tracking for further diagnosis. There are also intraoperative applications for wireless sensor networks (WSNs). Surgical instruments embedded with Micro-Electromechanical System (MEMS) sensors provide immediate feedback about a patient's condition to doctors during surgery including temperature, pressure, strain, or biochemical reactions. Finally, ultra-wideband combined with WSNs provides a robust platform for developing WSNs which includes accurate 3-D positioning and high data rate or low data rate digital communication with optimized performance for indoor environments which contain high amounts of multipath (e.g. metallic) interference.","PeriodicalId":430449,"journal":{"name":"2011 IEEE Topical Conference on Biomedical Wireless Technologies, Networks, and Sensing Systems","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115409906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-03-07DOI: 10.1109/BIOWIRELESS.2011.5724356
E. Martin
Gait analysis using wireless accelerometers deployed as body area networks can provide valuable information for multiple health-related applications. Within this field, stride length estimation represents a difficult task. In this paper we present a novel method to estimate stride length through the application of the wavelet transform to the signal obtained from a wireless accelerometer on the waist. We also introduce a novel metric to determine the level of the wavelet transform detail coefficients from which the step frequency can be directly extracted. Additionally, we show the correlation between the energy of the wavelet transform approximation coefficients and the speed of the gait.
{"title":"Novel method for stride length estimation with body area network accelerometers","authors":"E. Martin","doi":"10.1109/BIOWIRELESS.2011.5724356","DOIUrl":"https://doi.org/10.1109/BIOWIRELESS.2011.5724356","url":null,"abstract":"Gait analysis using wireless accelerometers deployed as body area networks can provide valuable information for multiple health-related applications. Within this field, stride length estimation represents a difficult task. In this paper we present a novel method to estimate stride length through the application of the wavelet transform to the signal obtained from a wireless accelerometer on the waist. We also introduce a novel metric to determine the level of the wavelet transform detail coefficients from which the step frequency can be directly extracted. Additionally, we show the correlation between the energy of the wavelet transform approximation coefficients and the speed of the gait.","PeriodicalId":430449,"journal":{"name":"2011 IEEE Topical Conference on Biomedical Wireless Technologies, Networks, and Sensing Systems","volume":"234 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117184408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-03-07DOI: 10.1109/BIOWIRELESS.2011.5724348
Changzhan Gu, Ruijiang Li, Changzhi Li, Steve B. Jiang
Respiration-gated radiation therapy is a promising treatment modality that precisely delivers prescribed radiation dose to the lung tumor while minimizing the incidence and severity of normal tissue complications. Conventional gating techniques either rely on implanted fiducial markers or external surrogates such as markers placed on patients' abdomen. They are either invasive to the patients or do not have sufficient accuracy. In this paper, we present a non-contact Doppler radar method to non-invasively measure the respiration signals, from which, accurate gating signals can be derived to control the linac. No marker is needed in our method, which makes it very convenient in use. We measured the respiration using a 5.8 GHz quadrature radar. Analysis of the measured signal is presented. It has been shown that the non-contact means of respiration measurement is able to supply reliable breathing motions and accurate gating signals for radiotherapy of mobile tumors.
{"title":"Doppler radar respiration measurement for gated lung cancer radiotherapy","authors":"Changzhan Gu, Ruijiang Li, Changzhi Li, Steve B. Jiang","doi":"10.1109/BIOWIRELESS.2011.5724348","DOIUrl":"https://doi.org/10.1109/BIOWIRELESS.2011.5724348","url":null,"abstract":"Respiration-gated radiation therapy is a promising treatment modality that precisely delivers prescribed radiation dose to the lung tumor while minimizing the incidence and severity of normal tissue complications. Conventional gating techniques either rely on implanted fiducial markers or external surrogates such as markers placed on patients' abdomen. They are either invasive to the patients or do not have sufficient accuracy. In this paper, we present a non-contact Doppler radar method to non-invasively measure the respiration signals, from which, accurate gating signals can be derived to control the linac. No marker is needed in our method, which makes it very convenient in use. We measured the respiration using a 5.8 GHz quadrature radar. Analysis of the measured signal is presented. It has been shown that the non-contact means of respiration measurement is able to supply reliable breathing motions and accurate gating signals for radiotherapy of mobile tumors.","PeriodicalId":430449,"journal":{"name":"2011 IEEE Topical Conference on Biomedical Wireless Technologies, Networks, and Sensing Systems","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125352781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-03-07DOI: 10.1109/BIOWIRELESS.2011.5724344
C. Mikeka, H. Arai
In this paper, we describe an RF energy-harvesting circuit printed on a single FR4 substrate to ensure compact and low profile design at 2.1 GHz. The circuit integrates a notched Circular Microstrip Patch Antenna (CMPA) with a fully matched single diode rectifier to form an efficient rectifying antenna. By cutting two electrically small triangular notches, at 457#x00B0; and 315#x00B0; of the patch, it is possible to cut-out the 2nd and 3rd harmonics generated by the single diode rectifier, thereby eliminating the need to use the complicated and lossy 0.5 dB ripple Chebyshev low pass filter at the input of the rectifier. In this way, we achieved 2.7V DC=OUT by measurement, a value which is 4 times larger than conventional 0.65V DC=OUT at ≤ 0dBm RF incidence. The proposed rectenna circuit is worn as fabric on a prosthetic leg to provide power for the patient's batteryless health monitoring sensor radio.
{"title":"Notched Circular Microstrip Patch Antenna integrated with a single diode rectifier for energy-harvesting prosthetic leg","authors":"C. Mikeka, H. Arai","doi":"10.1109/BIOWIRELESS.2011.5724344","DOIUrl":"https://doi.org/10.1109/BIOWIRELESS.2011.5724344","url":null,"abstract":"In this paper, we describe an RF energy-harvesting circuit printed on a single FR4 substrate to ensure compact and low profile design at 2.1 GHz. The circuit integrates a notched Circular Microstrip Patch Antenna (CMPA) with a fully matched single diode rectifier to form an efficient rectifying antenna. By cutting two electrically small triangular notches, at 457#x00B0; and 315#x00B0; of the patch, it is possible to cut-out the 2nd and 3rd harmonics generated by the single diode rectifier, thereby eliminating the need to use the complicated and lossy 0.5 dB ripple Chebyshev low pass filter at the input of the rectifier. In this way, we achieved 2.7V DC=OUT by measurement, a value which is 4 times larger than conventional 0.65V DC=OUT at ≤ 0dBm RF incidence. The proposed rectenna circuit is worn as fabric on a prosthetic leg to provide power for the patient's batteryless health monitoring sensor radio.","PeriodicalId":430449,"journal":{"name":"2011 IEEE Topical Conference on Biomedical Wireless Technologies, Networks, and Sensing Systems","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124198756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-03-07DOI: 10.1109/BIOWIRELESS.2011.5724353
M. Hella, A. Kempitiya, H. Mohamed, D. Borca-Tasciuc
This paper outlines the intelligence and portability requirements for future genetic analysis systems tailored to fast, low cost, and large scale population studies. Methods used in current research for DNA amplification and detection are discussed. The most significant shortcomings of current practises are their lack of the programmability required to generate different heating profiles to detect the correlation between different genetic components and specific diseases. In addition, none of the existing systems have the capability to quickly compare detected DNA with a bank of DNA signatures particular to a specific disease in a low cost, portable, and label-free process. Promising techniques relying on the advances in CMOS RF and sub-THz IC design are discussed wihin the context of programmable and parallel DNA amplification and detection platforms. The availability of such platforms can transform the field of genetic analysis, leading to personalized medicine and therapy.
{"title":"Ultra-high frequency IC design for intelligent genetic analysis systems","authors":"M. Hella, A. Kempitiya, H. Mohamed, D. Borca-Tasciuc","doi":"10.1109/BIOWIRELESS.2011.5724353","DOIUrl":"https://doi.org/10.1109/BIOWIRELESS.2011.5724353","url":null,"abstract":"This paper outlines the intelligence and portability requirements for future genetic analysis systems tailored to fast, low cost, and large scale population studies. Methods used in current research for DNA amplification and detection are discussed. The most significant shortcomings of current practises are their lack of the programmability required to generate different heating profiles to detect the correlation between different genetic components and specific diseases. In addition, none of the existing systems have the capability to quickly compare detected DNA with a bank of DNA signatures particular to a specific disease in a low cost, portable, and label-free process. Promising techniques relying on the advances in CMOS RF and sub-THz IC design are discussed wihin the context of programmable and parallel DNA amplification and detection platforms. The availability of such platforms can transform the field of genetic analysis, leading to personalized medicine and therapy.","PeriodicalId":430449,"journal":{"name":"2011 IEEE Topical Conference on Biomedical Wireless Technologies, Networks, and Sensing Systems","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125096424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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