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Keyness in maritime institutional law texts 海事制度法律文本中的凯恩斯
IF 0.6 0 LANGUAGE & LINGUISTICS
Linguistic Research
Pub Date : 2017-03-01 DOI: 10.17250/KHISLI.34.1.201703.002
Wenyu Lu, Sungmin Lee, Se-Eun Jhang
This study describes some characteristics of maritime institutional legal texts in terms of corpus methodology. We self-built two study corpora: a...
本文从语料库方法论的角度描述了海事制度法律文本的一些特征。我们自建了两个学习语料库:a…
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引用次数: 5
Clusterin and Pycr1 alterations associate with strain and model differences in susceptibility to experimental pancreatitis. Clusterin和Pycr1的改变与实验性胰腺炎易感性的品系和模型差异有关。
IF 3.1 0 LANGUAGE & LINGUISTICS
Linguistic Research
Pub Date : 2017-01-22 Epub Date: 2016-12-07 DOI: 10.1016/j.bbrc.2016.12.039
Sapna Iyer, Min-Jung Park, David Moons, Raymond Kwan, Jian Liao, Li Liu, M Bishr Omary

Acute pancreatitis has several underlying etiologies, and results in consequences ranging from mild to complex multi-organ failure. The wide range of pathology suggests a genetic predisposition for progression. We compared the susceptibility to acute pancreatitis in BALB/c and FVB/N mice, coupled with proteomic analysis, in order to identify potential protein associations with pancreatitis progression.

Methods: Pancreatitis was induced in BALB/c and FVB/N mice by administration of cerulein or feeding a choline-deficient, ethionine-supplemented (CDE) diet. Histology and changes in serum amylase were examined. Proteome profiling in cerulein-treated mice was performed using 2-dimensional differential in gel electrophoresis (2D-DIGE) followed by mass spectrometry analysis and biochemical validation.

Results: Male and female FVB/N mice manifested more severe cerulein-induced pancreatitis as compared with BALB/c mice, but both strains were similarly susceptible to CDE-induced pancreatitis. Few of the 2D-DIGE alterations were validated by immunoblotting. Clusterin was markedly up-regulated after cerulein-induced pancreatitis in FVB/N but less-so in BALB/c mice. Pyrroline-5-carboxylate reductase (Pycr1), an enzyme involved in proline biosynthesis, had higher basal levels in FVB/N male and female mouse pancreata compared with BALB/c pancreata, and was relatively more resistant to degradation in FVB/N pancreata. However, serum and pancreas tissue proline levels were similar in the two strains.

Conclusion: FVB/N is more susceptible than BALB/c mice to cerulein-induced but not CDE-induced pancreatitis. Most of the 2D-DIGE alterations in the two strains likely relate to posttranslational modifications rather than protein level differences. Clusterin levels increase dramatically in association with pancreatitis severity, while Pycr1 is higher in FVB/N versus BALB/c pancreata basally and after induction of pancreatitis. Changes in proline metabolism may represent a novel potential genetic modifier in the context of pancreatitis.

急性胰腺炎有多种潜在病因，导致的后果从轻微到复杂的多器官衰竭不等。病理变化的广泛性表明，急性胰腺炎的发展存在遗传易感性。我们比较了 BALB/c 和 FVB/N 小鼠对急性胰腺炎的易感性，并结合蛋白质组分析，以确定与胰腺炎进展相关的潜在蛋白质：给 BALB/c 和 FVB/N 小鼠注射胰岛素或喂食胆碱缺乏、乙硫氨酸补充（CDE）饮食诱发胰腺炎。对组织学和血清淀粉酶的变化进行了检测。使用二维差分凝胶电泳（2D-DIGE）对服用 Cerulein 的小鼠进行蛋白质组分析，然后进行质谱分析和生化验证：结果：与 BALB/c 小鼠相比，FVB/N 雄性和雌性小鼠表现出更严重的胰岛素诱导的胰腺炎，但这两个品系对 CDE 诱导的胰腺炎具有相似的易感性。免疫印迹验证了少数 2D-DIGE 改变。FVB/N小鼠在胭脂红诱导的胰腺炎后，Clusterin明显上调，但在BALB/c小鼠中上调较少。参与脯氨酸生物合成的吡咯啉-5-羧酸还原酶（Pycr1）在FVB/N雄性和雌性小鼠胰腺中的基础水平比在BALB/c小鼠胰腺中的基础水平高，而且在FVB/N小鼠胰腺中相对更耐降解。然而，两个品系的血清和胰腺组织中的脯氨酸水平相似：结论：FVB/N比BALB/c小鼠更容易受到cerulein诱导的胰腺炎的影响，而不是CDE诱导的胰腺炎。这两个品系的大多数 2D-DIGE 改变可能与翻译后修饰有关，而不是蛋白质水平的差异。Clusterin水平随着胰腺炎的严重程度而急剧增加，而在FVB/N和BALB/c胰腺中，Pycr1的水平在基础上和诱导胰腺炎后都要比BALB/c高。脯氨酸代谢的变化可能是胰腺炎的一个新的潜在遗传修饰因子。
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引用次数: 4
Meaning classes of evidential implications across languages 跨语言的证据意义类
IF 0.6 0 LANGUAGE & LINGUISTICS
Linguistic Research
Pub Date : 2016-12-01 DOI: 10.17250/KHISLI.33.3.201612.004
Jungmee Lee
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引用次数: 1
Revisiting Korean long form negative question : A usage-based perspective 再看韩语长否定问句:基于用法的观点
IF 0.6 0 LANGUAGE & LINGUISTICS
Linguistic Research
Pub Date : 2016-12-01 DOI: 10.17250/KHISLI.33.3.201612.002
Ahrim Kim
Unlike most of the previous work on the semantic/functional ambiguity of the long form negative question construction in Korean which mainly focused...
与以往大多数关于韩语长形式否定疑问句结构的语义/功能歧义的研究不同，这些研究主要集中在……
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引用次数: 1
Optimal prosody for different proficiency Chinese talkers of English : Pitch and speech rate 不同水平的中国英语说话者的最佳韵律:音高和语速
IF 0.6 0 LANGUAGE & LINGUISTICS
Linguistic Research
Pub Date : 2016-12-01 DOI: 10.17250/KHISLI.33.3.201612.006
J. Lee
This paper investigates native listeners’ perceived accentedness for pitch- and duration-manipulated speech of Chinese L2 talkers and compared it with...
本文研究了母语听者对汉语第二语言的音高和时长操纵语音的重音感知，并将其与英语进行了比较。
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引用次数: 1
The brains of speech experts and non-experts compared : An fMRI investigation of phonological processing 语音专家和非专家的大脑比较:语音处理的功能磁共振成像研究
IF 0.6 0 LANGUAGE & LINGUISTICS
Linguistic Research
Pub Date : 2016-12-01 DOI: 10.17250/khisli.33.3.201612.007
Haeil Park
The present study aims to investigate whether there are distinctions in language-related brain function between speech experts and control subjects,...
本研究旨在调查语言专家和对照组之间的语言相关脑功能是否存在差异。
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引用次数: 0
On what determines the modification relation in Korean adnominal adjunct RDCs 论韩文副语修饰关系的决定因素
IF 0.6 0 LANGUAGE & LINGUISTICS
Linguistic Research
Pub Date : 2016-12-01 DOI: 10.17250/KHISLI.33.3.201612.001
Daeho Chung
This work addresses the question of how adnominal appendices in the adjunct right dislocation construction (ADJ-RDC) in Korean resolve their...
这项工作解决了韩国语中辅音右位错结构(jj - rdc)中的辅音附录如何解决其问题。
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引用次数: 3
A functional account for the productivity of English -er nominals 英语-er名词的功能解释
IF 0.6 0 LANGUAGE & LINGUISTICS
Linguistic Research
Pub Date : 2016-12-01 DOI: 10.17250/KHISLI.33.3.201612.005
Cheongmin Yook, Yong-hun Lee
Yook, Cheongmin and Yong-hun Lee. A functional account for the productivity of English -er nominals. Linguistic Research 33(3), 463-485. This paper offers a descriptive generalization on the English -er nominalization based on a functional-cognitive-semantic concept habituality as a condition on -er nominalization. Fairly an extensive literature on this topic has so far been offered in terms of syntactic structures, particularly arguments structure of the base verbs. Many of these research works do shed a new light on the various facets of English -er nominalization, but still missing from these discussions is a comprehensive understanding of the phenomena revolving around these nominalizations. These works simply exclude from their discussion the -er nominals that are derived from nouns, adjectives, prepositions, and various phrases simply because they do not involve argument structure. Various proposals couched in functional-semantic framework offer a comprehensive account for this phenomenon. Our proposal is an effort in this line of approach. We argue that -er nominalization is allowed if habituality or durativity is secured enough to be considered as representing inherent properties. (Hallym University · Chungnam National University)
李旭、清民、李容勋。英语-er名词的功能解释。语言学研究33(3)，463-485。本文从功能-认知-语义概念习惯作为-er名词化的条件出发，对英语-er名词化进行了描述性概括。到目前为止，关于这一主题的文献已经相当广泛，主要集中在句法结构方面，特别是基本动词的论点结构。这些研究工作确实为英语-er名词化的各个方面提供了新的视角，但这些讨论仍然缺少对这些名词化现象的全面理解。这些著作简单地排除了从名词、形容词、介词和各种短语派生出来的-er名词，因为它们不涉及论点结构。在功能语义框架中提出的各种建议为这一现象提供了一个全面的解释。我们的建议就是在这方面的努力。我们认为-er名词化是允许的，如果习惯或持久性足够安全，被认为是表征固有属性。(翰林大学·忠南大学)
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引用次数: 0
On the emergence of the stance-marking function of English adverbs : A case of intensifiers 论英语副词位置标记功能的产生:以加强语为例
IF 0.6 0 LANGUAGE & LINGUISTICS
Linguistic Research
Pub Date : 2016-12-01 DOI: 10.17250/KHISLI.33.3.201612.003
Seongha Rhee
Stance-marking is nearly ubiquitous and possibly inevitable in most instances of language use. One of the prominent functions of English adverbs is...
在语言使用的大多数情况下，站位标记几乎无处不在，而且可能是不可避免的。英语副词的一个突出功能是……
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引用次数: 10
Linearization strategies in Korean language production 韩国语制作中的线性化策略
IF 0.6 0 LANGUAGE & LINGUISTICS
Linguistic Research
Pub Date : 2016-12-01 DOI: 10.17250/KHISLI.33.3.201612.008
Alakh Dhari, Soonhyuck Park
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引用次数: 0
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