首页 > 最新文献

Journal of Digestive Endoscopy最新文献

英文 中文
Environmentally Sustainable Endoscopy Practices 环境可持续的内窥镜检查实践
Pub Date : 2023-10-09 DOI: 10.1055/s-0043-1775873
Mayank Jain
Abstract Climate change affects each and every one of us and has far reaching consequences. As healthcare providers and responsible citizens, it is our duty to make our practices environmentally sustainable. Endoscopy practice involves frequent use of single-use items, resource-heavy decontamination practices, water consumption, patient and staff travel as well as high electricity consumption. The present review highlights the measures that can be taken to reduce the carbon footprint of endoscopy practice. Proper waste management, judicious use of electricity, proper selection of cases for anesthesia and biopsy, and appropriate use of noninvasive tests in practice are discussed in the review.
气候变化影响着我们每一个人,并产生深远的后果。作为医疗保健提供者和负责任的公民,我们有责任使我们的做法具有环境可持续性。内窥镜检查操作涉及频繁使用一次性物品、资源密集型净化操作、水消耗、患者和工作人员旅行以及高电力消耗。目前的审查强调了可以采取的措施,以减少内窥镜检查实践的碳足迹。本综述讨论了适当的废物管理、合理用电、正确选择麻醉和活检病例以及在实践中适当使用无创检查。
{"title":"Environmentally Sustainable Endoscopy Practices","authors":"Mayank Jain","doi":"10.1055/s-0043-1775873","DOIUrl":"https://doi.org/10.1055/s-0043-1775873","url":null,"abstract":"Abstract Climate change affects each and every one of us and has far reaching consequences. As healthcare providers and responsible citizens, it is our duty to make our practices environmentally sustainable. Endoscopy practice involves frequent use of single-use items, resource-heavy decontamination practices, water consumption, patient and staff travel as well as high electricity consumption. The present review highlights the measures that can be taken to reduce the carbon footprint of endoscopy practice. Proper waste management, judicious use of electricity, proper selection of cases for anesthesia and biopsy, and appropriate use of noninvasive tests in practice are discussed in the review.","PeriodicalId":43098,"journal":{"name":"Journal of Digestive Endoscopy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135044458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of Over-the-Scope Clips Compared to Standard Therapy for Nonvariceal Upper Gastrointestinal Bleeding—A Systematic Review and Meta-analysis of Randomized Trials 与非静脉曲张上消化道出血的标准治疗相比,超镜夹的疗效——随机试验的系统评价和荟萃分析
Pub Date : 2023-10-09 DOI: 10.1055/s-0043-1774773
Suprabhat Giri, Sidharth Harindranath, Marko Kozyk, Aditya Kale, Vaneet Jearth, Sridhar Sundaram
Abstract Background The current standard of treatment for nonvariceal upper gastrointestinal bleeding (NVUGIB) includes endoscopic hemostasis with either through-the-scope clips or thermal therapy. However, they may be associated with rebleeding, especially in high-risk ulcers. Over-the-scope clips (OTSC) have been demonstrated in multiple recent studies to be an effective measure for NVUGIB. We aimed to analyze the current literature on standard therapy with OTSC to manage NVUGIB. Methods A meta-analysis was performed by pooling the data from randomized studies obtained from a comprehensive search of Medline, Embase, and Scopus from inception to February 2023. The outcomes analyzed included rates of persistent bleeding, rebleeding, mortality, and duration of hospitalization. Results A total of five studies were included in the final analysis. There was no significant difference in the risk of persistent bleeding between the groups, with a risk ratio (RR) of 0.29 (95% confidence interval [CI]: 0.07–1.27). The use of OTSC was associated with a significantly lower risk of 7-day and 30-day rebleeding compared with standard therapy with RR of 0.30 (95% CI: 0.16–0.59) and 0.42 (95% CI: 0.24–0.72), respectively. There was no difference in the risk of 30-day mortality or the duration of hospitalization. There was no change in the effect on subgroup analysis of studies using OTSC as first-line therapy. Conclusion The use of OTSC can reduce the rebleeding rates after endoscopic hemostasis. However, they may not reduce the risk of persistent bleeding or mortality. Future studies are required on the cost-efficacy of this modality.
背景目前治疗非静脉曲张性上消化道出血(NVUGIB)的标准包括内镜下止血,通过内镜夹或热疗法。然而,它们可能与再出血有关,特别是在高风险溃疡中。在最近的多项研究中,超镜夹(OTSC)已被证明是治疗NVUGIB的有效措施。我们的目的是分析目前关于OTSC治疗NVUGIB的标准治疗文献。方法通过综合检索Medline、Embase和Scopus自成立以来至2023年2月的随机研究数据,进行荟萃分析。结果分析包括持续出血、再出血、死亡率和住院时间。结果共纳入5项研究。两组持续出血风险无显著差异,风险比(RR)为0.29(95%可信区间[CI]: 0.07-1.27)。与标准治疗相比,使用OTSC与7天和30天再出血风险显著降低相关,RR分别为0.30 (95% CI: 0.16-0.59)和0.42 (95% CI: 0.24-0.72)。30天死亡风险和住院时间没有差异。在使用OTSC作为一线治疗的研究中,亚组分析的效果没有变化。结论使用OTSC可降低内镜下止血后的再出血率。然而,它们可能不会降低持续出血或死亡的风险。今后需要对这种方式的成本效益进行研究。
{"title":"Efficacy of Over-the-Scope Clips Compared to Standard Therapy for Nonvariceal Upper Gastrointestinal Bleeding—A Systematic Review and Meta-analysis of Randomized Trials","authors":"Suprabhat Giri, Sidharth Harindranath, Marko Kozyk, Aditya Kale, Vaneet Jearth, Sridhar Sundaram","doi":"10.1055/s-0043-1774773","DOIUrl":"https://doi.org/10.1055/s-0043-1774773","url":null,"abstract":"Abstract Background The current standard of treatment for nonvariceal upper gastrointestinal bleeding (NVUGIB) includes endoscopic hemostasis with either through-the-scope clips or thermal therapy. However, they may be associated with rebleeding, especially in high-risk ulcers. Over-the-scope clips (OTSC) have been demonstrated in multiple recent studies to be an effective measure for NVUGIB. We aimed to analyze the current literature on standard therapy with OTSC to manage NVUGIB. Methods A meta-analysis was performed by pooling the data from randomized studies obtained from a comprehensive search of Medline, Embase, and Scopus from inception to February 2023. The outcomes analyzed included rates of persistent bleeding, rebleeding, mortality, and duration of hospitalization. Results A total of five studies were included in the final analysis. There was no significant difference in the risk of persistent bleeding between the groups, with a risk ratio (RR) of 0.29 (95% confidence interval [CI]: 0.07–1.27). The use of OTSC was associated with a significantly lower risk of 7-day and 30-day rebleeding compared with standard therapy with RR of 0.30 (95% CI: 0.16–0.59) and 0.42 (95% CI: 0.24–0.72), respectively. There was no difference in the risk of 30-day mortality or the duration of hospitalization. There was no change in the effect on subgroup analysis of studies using OTSC as first-line therapy. Conclusion The use of OTSC can reduce the rebleeding rates after endoscopic hemostasis. However, they may not reduce the risk of persistent bleeding or mortality. Future studies are required on the cost-efficacy of this modality.","PeriodicalId":43098,"journal":{"name":"Journal of Digestive Endoscopy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135044457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Timing of Endoscopic Transmural Drainage for Pancreatic Necrosis: Expanding the Horizon! 内镜下胰腺坏死经壁引流的时机:扩大视野!
Pub Date : 2023-09-28 DOI: 10.1055/s-0043-1775758
Surinder Singh Rana
Abstract Endoscopic transluminal drainage (ETD) has been traditionally performed on collections that have a well-formed enclosing wall and therefore it was advocated for walled-off necrosis. However, recently, retrospective studies have reported that ETD can be safely performed in patients with collections without a well-formed wall also and reported outcomes better than those patients who were treated with percutaneous drainage. The evidence for safety and efficacy of early ETD for infected pancreatic necrosis is scanty and therefore, in this news and views, I will be discussing a recently published systematic review and meta-analysis comparing outcomes after early (<4 weeks) and standard (≥4 weeks) drainage of pancreatic necrosis.
内镜下腔内引流(ETD)传统上是对具有良好围壁的集合进行的,因此它被提倡用于壁闭塞性坏死。然而,最近,回顾性研究报道,对于没有形成良好壁的收集患者,也可以安全地进行ETD,并且报道的结果优于经皮引流治疗的患者。早期ETD治疗感染性胰腺坏死的安全性和有效性的证据很少,因此,在这篇新闻和观点中,我将讨论最近发表的一项系统综述和荟萃分析,比较早期(4周)和标准(≥4周)胰腺坏死引流的结果。
{"title":"Timing of Endoscopic Transmural Drainage for Pancreatic Necrosis: Expanding the Horizon!","authors":"Surinder Singh Rana","doi":"10.1055/s-0043-1775758","DOIUrl":"https://doi.org/10.1055/s-0043-1775758","url":null,"abstract":"Abstract Endoscopic transluminal drainage (ETD) has been traditionally performed on collections that have a well-formed enclosing wall and therefore it was advocated for walled-off necrosis. However, recently, retrospective studies have reported that ETD can be safely performed in patients with collections without a well-formed wall also and reported outcomes better than those patients who were treated with percutaneous drainage. The evidence for safety and efficacy of early ETD for infected pancreatic necrosis is scanty and therefore, in this news and views, I will be discussing a recently published systematic review and meta-analysis comparing outcomes after early (<4 weeks) and standard (≥4 weeks) drainage of pancreatic necrosis.","PeriodicalId":43098,"journal":{"name":"Journal of Digestive Endoscopy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135345250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endoscopic Submucosal Dissection for Early Gastric Cancer in A Cirrhotic Patient: Case Report and Review of Literature 内镜下粘膜下剥离术治疗肝硬化早期胃癌1例报告及文献复习
Pub Date : 2023-09-28 DOI: 10.1055/s-0043-1773773
Unique Tyagi, Sridhar Sundaram, Aadish Kumar Jain, Akhil Mahajan, Rahul Puri, Prachi Patil, Shaesta Mehta
Abstract Endoscopic resection techniques like endoscopic mucosal resection and endoscopic submucosal dissection have become the cornerstone for the management of early cancers of the gastrointestinal tract. Risks associated with endoscopic resection may be exacerbated by the presence of background cirrhosis with its attendant complications. With complex alterations in hemostasis in patients with cirrhosis, management of patients undergoing endoscopic resection is more challenging. In this article we discuss a case of early gastric cancer in a patient with background chronic liver disease and thrombocytopenia managed using endoscopic submucosal dissection.
内镜粘膜切除、内镜粘膜下剥离等内镜切除技术已成为早期胃肠道肿瘤治疗的基石。内窥镜切除的相关风险可能会因背景性肝硬化及其并发症而加剧。随着肝硬化患者止血功能的复杂改变,内镜切除患者的管理更具挑战性。在这篇文章中,我们讨论了一例早期胃癌患者的背景慢性肝病和血小板减少使用内镜粘膜下解剖处理。
{"title":"Endoscopic Submucosal Dissection for Early Gastric Cancer in A Cirrhotic Patient: Case Report and Review of Literature","authors":"Unique Tyagi, Sridhar Sundaram, Aadish Kumar Jain, Akhil Mahajan, Rahul Puri, Prachi Patil, Shaesta Mehta","doi":"10.1055/s-0043-1773773","DOIUrl":"https://doi.org/10.1055/s-0043-1773773","url":null,"abstract":"Abstract Endoscopic resection techniques like endoscopic mucosal resection and endoscopic submucosal dissection have become the cornerstone for the management of early cancers of the gastrointestinal tract. Risks associated with endoscopic resection may be exacerbated by the presence of background cirrhosis with its attendant complications. With complex alterations in hemostasis in patients with cirrhosis, management of patients undergoing endoscopic resection is more challenging. In this article we discuss a case of early gastric cancer in a patient with background chronic liver disease and thrombocytopenia managed using endoscopic submucosal dissection.","PeriodicalId":43098,"journal":{"name":"Journal of Digestive Endoscopy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135344701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Small Bowel Capsule Endoscopy: Benefits of Rereading Rather than Repeating – a Single Blinded Randomized Study 小肠胶囊内窥镜检查:重读而不是重复的好处-一项单盲随机研究
Pub Date : 2023-09-22 DOI: 10.1055/s-0043-1774807
Alamir-Noureddine AlAyoubi, Ayman Tabcheh, Nourhane Obeid, Antoine Challita, Judy Matta, Said Farhat
Abstract Introduction Small bowel capsule endoscopy (SBCE) technology detects small bowel lesions. Many factors affect its sensitivity. SBCE is also costly, and patients might not be able to repeat the test when results are equivocal. Instead of repeating the test, reading the results by two endoscopists might provide a better or a cheaper option in the right settings. We studied the sensitivity of SBCE when read by two different physicians and checked if, rather than repeating the examination, rereading the results improved its sensitivity. Furthermore, we studied the effect of small bowel transit time (SBTT) on the diagnostic yield. Methods A retrospective cohort study on capsule endoscopies was conducted between 2018 and 2019 in a tertiary care center in Lebanon. A total of 42 patients with anemia or obscure gastrointestinal bleed were included for SBCE after a negative evaluation with upper and lower gastrointestinal (GI) endoscopy. Two specialists read the results. The second physician was blinded from the first reader's results. We compared the sensitivity of the two readings. SBTT correlation with the diagnostic yield was calculated. Results Out of 42 patients, 18 tested positive in the first reading and 31 in the second reading. The diagnostic yield increased from 43 to 74% (p = 0.0043). Among the 33 patients who had a documented SBTT, longer SBTT correlated with a higher diagnostic yield (odds ratio [OR] > 1), but no statistical significance was demonstrated. Conclusion Within the limitations of this study, we found that rereading capsule endoscopy can be more cost-effective than repeating the test.
小肠胶囊内镜(SBCE)技术检测小肠病变。影响其灵敏度的因素很多。SBCE也很昂贵,当结果不明确时,患者可能无法重复测试。而不是重复测试,阅读结果由两个内窥镜医生可能会提供一个更好或更便宜的选择在正确的设置。我们研究了由两名不同的医生阅读时SBCE的敏感性,并检查了重复阅读结果是否提高了其敏感性,而不是重复检查。此外,我们还研究了小肠运输时间(SBTT)对诊断率的影响。方法2018 - 2019年在黎巴嫩某三级医疗中心进行胶囊内窥镜回顾性队列研究。共有42例贫血或消化道隐晦出血患者在上、下消化道内镜检查结果阴性后接受SBCE检查。两位专家宣读了结果。第二位医生对第一位读者的结果一无所知。我们比较了两种读数的灵敏度。计算SBTT与诊断率的相关性。结果42例患者中,18例患者一读呈阳性,31例患者二读呈阳性。诊断率从43%提高到74% (p = 0.0043)。在33例有SBTT记录的患者中,较长的SBTT与较高的诊断率相关(优势比[OR] >1),但无统计学意义。结论在本研究的局限性内,我们发现重新阅读胶囊内窥镜检查比重复检查更具成本效益。
{"title":"Small Bowel Capsule Endoscopy: Benefits of Rereading Rather than Repeating – a Single Blinded Randomized Study","authors":"Alamir-Noureddine AlAyoubi, Ayman Tabcheh, Nourhane Obeid, Antoine Challita, Judy Matta, Said Farhat","doi":"10.1055/s-0043-1774807","DOIUrl":"https://doi.org/10.1055/s-0043-1774807","url":null,"abstract":"Abstract Introduction Small bowel capsule endoscopy (SBCE) technology detects small bowel lesions. Many factors affect its sensitivity. SBCE is also costly, and patients might not be able to repeat the test when results are equivocal. Instead of repeating the test, reading the results by two endoscopists might provide a better or a cheaper option in the right settings. We studied the sensitivity of SBCE when read by two different physicians and checked if, rather than repeating the examination, rereading the results improved its sensitivity. Furthermore, we studied the effect of small bowel transit time (SBTT) on the diagnostic yield. Methods A retrospective cohort study on capsule endoscopies was conducted between 2018 and 2019 in a tertiary care center in Lebanon. A total of 42 patients with anemia or obscure gastrointestinal bleed were included for SBCE after a negative evaluation with upper and lower gastrointestinal (GI) endoscopy. Two specialists read the results. The second physician was blinded from the first reader's results. We compared the sensitivity of the two readings. SBTT correlation with the diagnostic yield was calculated. Results Out of 42 patients, 18 tested positive in the first reading and 31 in the second reading. The diagnostic yield increased from 43 to 74% (p = 0.0043). Among the 33 patients who had a documented SBTT, longer SBTT correlated with a higher diagnostic yield (odds ratio [OR] &gt; 1), but no statistical significance was demonstrated. Conclusion Within the limitations of this study, we found that rereading capsule endoscopy can be more cost-effective than repeating the test.","PeriodicalId":43098,"journal":{"name":"Journal of Digestive Endoscopy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136015036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Capsule Endoscopy in Inflammatory Bowel Disease: A Systematic Review 胶囊内窥镜在炎症性肠病中的应用:系统综述
Pub Date : 2023-09-01 DOI: 10.1055/s-0043-1766122
Partha Pal, Rupa Banerjee, Rajesh Gupta, Palle Manohar Reddy, D Nageshwar Reddy, Manu Tandan
Abstract The role of video capsule endoscopy (VCE) in inflammatory bowel disease (IBD) has evolved from small bowel to a panenteric evaluation tool over the past two decades. We systematically reviewed the techniques, applications, outcomes, and complications of VCE in IBD. A systematic literature search was performed using PubMed, Embase, and Medline. All relevant original articles involving VCE in IBD were included from 2003 to July 2022. After screening 3,089 citations, finally 201 references were included. The diagnostic yield of VCE in suspected Crohn's disease (CD) was highly variable (6–80%) with excellent sensitivity (77–93%) and specificity (80–89%). The diagnostic yield in known CD was 52 to 88.3% leading to a change in management (26–75%) and disease reclassification with variable retention rates. VCE was superior to small bowel series, computed tomography (CT) and could be better than magnetic resonance enterography (MRE), especially for proximal and superficial lesions. Colon or panenteric VCE has strong correlation to ileo-colonoscopy (IC) and combined magnetic resonance imaging and IC, respectively. The VCE retention rate in CD is higher in known CD which significantly decreases after the negative patency capsule test or CT/MRE. VCE can identify lesions beyond the reach of IC in postoperative CD. Colon Capsule Endoscopy is a noninvasive monitoring tool in ulcerative colitis (UC) having a strong correlation with IC and may uncover small bowel involvement. VCE is specifically useful in IBD-unclassified (IBD-U) which can lead to the diagnosis of CD in 16.7 to 61.5%. Various scoring systems have been established and validated for small bowel CD (Lewis score and capsule endoscopy CD activity index—CECDAI), UC (capsule scoring of UC: Capsule Scoring of Ulcerative Colitis), panenteric evaluation (Capsule Endoscopy Crohn's Disease Activity Index, Elaikim score), and flare prediction (APEX score). Technological advances include double head, three-dimensional reconstruction, sampling system, panoramic view (344 and 360 degree lateral), and panenteric capsule. Artificial intelligence and software like TOP100 and Quickview can help reduce capsule reading time with excellent sensitivity and specificity. VCE in IBD has widespread application in suspected and known small bowel CD, monitoring of UC, postoperative CD, IBD-U, and for panenteric evaluation. Patency capsule testing helps to reduce retention rates significantly. Artificial intelligence and technical advances can help evolve this novel technology.
在过去的二十年里,视频胶囊内镜(VCE)在炎症性肠病(IBD)中的作用已经从小肠发展到全肠的评估工具。我们系统地回顾了VCE在IBD中的技术、应用、结果和并发症。使用PubMed、Embase和Medline进行系统的文献检索。收录了2003年至2022年7月IBD中涉及VCE的所有相关原创文章。筛选3089篇文献,最终纳入201篇文献。VCE对疑似克罗恩病(CD)的诊断率变化很大(6-80%),具有良好的敏感性(77-93%)和特异性(80-89%)。已知CD的诊断率为52 - 88.3%,导致治疗方法的改变(26-75%)和疾病重新分类,保留率不同。VCE优于小肠系列,计算机断层扫描(CT),可优于磁共振肠图(MRE),特别是近端和浅表病变。结肠或panenteric VCE分别与回肠结肠镜检查(IC)和磁共振成像与IC相结合有很强的相关性。已知CD中VCE保留率较高,经开放囊试验阴性或CT/MRE后明显降低。VCE可以识别术后CD中IC无法触及的病变。结肠胶囊内窥镜是溃疡性结肠炎(UC)的一种无创监测工具,与IC有很强的相关性,可以发现小肠受损伤。VCE在未分类ibd (IBD-U)中特别有用,其诊断为CD的比例为16.7%至61.5%。小肠CD (Lewis评分和胶囊内窥镜CD活动指数- cecdai)、UC (UC胶囊评分:溃疡性结肠炎胶囊评分)、全肠评估(胶囊内窥镜克罗恩病活动指数、Elaikim评分)和急性发作预测(APEX评分)的评分系统已经建立并得到验证。技术进步包括双头、三维重建、采样系统、全景(344度和360度横向)、泛肠胶囊。人工智能和TOP100、Quickview等软件可以帮助缩短胶囊读取时间,具有出色的灵敏度和特异性。VCE在IBD中广泛应用于疑似和已知的小肠CD、UC监测、术后CD、IBD- u以及全肠评价。通畅胶囊测试有助于显著降低滞留率。人工智能和技术进步可以帮助发展这种新技术。
{"title":"Capsule Endoscopy in Inflammatory Bowel Disease: A Systematic Review","authors":"Partha Pal, Rupa Banerjee, Rajesh Gupta, Palle Manohar Reddy, D Nageshwar Reddy, Manu Tandan","doi":"10.1055/s-0043-1766122","DOIUrl":"https://doi.org/10.1055/s-0043-1766122","url":null,"abstract":"Abstract The role of video capsule endoscopy (VCE) in inflammatory bowel disease (IBD) has evolved from small bowel to a panenteric evaluation tool over the past two decades. We systematically reviewed the techniques, applications, outcomes, and complications of VCE in IBD. A systematic literature search was performed using PubMed, Embase, and Medline. All relevant original articles involving VCE in IBD were included from 2003 to July 2022. After screening 3,089 citations, finally 201 references were included. The diagnostic yield of VCE in suspected Crohn's disease (CD) was highly variable (6–80%) with excellent sensitivity (77–93%) and specificity (80–89%). The diagnostic yield in known CD was 52 to 88.3% leading to a change in management (26–75%) and disease reclassification with variable retention rates. VCE was superior to small bowel series, computed tomography (CT) and could be better than magnetic resonance enterography (MRE), especially for proximal and superficial lesions. Colon or panenteric VCE has strong correlation to ileo-colonoscopy (IC) and combined magnetic resonance imaging and IC, respectively. The VCE retention rate in CD is higher in known CD which significantly decreases after the negative patency capsule test or CT/MRE. VCE can identify lesions beyond the reach of IC in postoperative CD. Colon Capsule Endoscopy is a noninvasive monitoring tool in ulcerative colitis (UC) having a strong correlation with IC and may uncover small bowel involvement. VCE is specifically useful in IBD-unclassified (IBD-U) which can lead to the diagnosis of CD in 16.7 to 61.5%. Various scoring systems have been established and validated for small bowel CD (Lewis score and capsule endoscopy CD activity index—CECDAI), UC (capsule scoring of UC: Capsule Scoring of Ulcerative Colitis), panenteric evaluation (Capsule Endoscopy Crohn's Disease Activity Index, Elaikim score), and flare prediction (APEX score). Technological advances include double head, three-dimensional reconstruction, sampling system, panoramic view (344 and 360 degree lateral), and panenteric capsule. Artificial intelligence and software like TOP100 and Quickview can help reduce capsule reading time with excellent sensitivity and specificity. VCE in IBD has widespread application in suspected and known small bowel CD, monitoring of UC, postoperative CD, IBD-U, and for panenteric evaluation. Patency capsule testing helps to reduce retention rates significantly. Artificial intelligence and technical advances can help evolve this novel technology.","PeriodicalId":43098,"journal":{"name":"Journal of Digestive Endoscopy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135735327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical, Endoscopic, and Histologic Characteristics of Patients with Solitary Rectal Ulcer Syndrome at a Tertiary Care Center 三级保健中心孤立性直肠溃疡综合征患者的临床、内窥镜和组织学特征
Pub Date : 2023-09-01 DOI: 10.1055/s-0043-1770922
Syed Shafiq
Abstract Objective Solitary rectal ulcer syndrome (SRUS) is a chronic disorder of defecation presenting with bleed per rectum, mucorrhea, tenesmus, perianal discomfort, etc. We aim to report clinical, endoscopic, and histologic features of SRUS in patients who underwent either colonoscopy or sigmoidoscopy at our center. Materials and Methods We performed retrospective analysis of all patients diagnosed with SRUS on endoscopy and confirmed by histopathologic examination at our center between January 2010 and June 2022. Data retrieved included demographic details, clinical features along with endoscopic, and histopathological findings of SRUS patients. Results The study included 132 patients with SRUS with mean (± standard deviation) age of 45 (± 20.6) years and male to female ratio of 1.5:1. While most of the patients presented with a combination of symptoms, the most common clinical presentation was bleeding per rectum (82%). Rectal ulcers, either single or multiple, were the predominant findings on endoscopy followed by polypoidal lesions. Histology showed fibromuscular obliteration and crypt distortion in all patients. Biofeedback training, lifestyle changes, and sucralfate enema were successful in about 87% of the patients at the end of 6 weeks and about 76% at the end of 12 weeks with surgery for rectal prolapse being performed in two of our patients. Conclusion SRUS presents with a myriad of symptoms and requires a high index of suspicion by the treating physician(s). While the most common presenting symptom in our study was rectal bleed rectal bleed; ulcers, either solitary or multiple, ulcers, either solitary or multiple, were the commonest endoscopy findings. Endoscopic findings along with histopathology confirm the diagnosis.
摘要目的孤立性直肠溃疡综合征(SRUS)是一种慢性排便疾病,主要表现为直肠出血、黏膜漏、尿急、肛周不适等。我们的目的是报告在我们中心接受结肠镜或乙状结肠镜检查的患者的临床、内窥镜和组织学特征。材料与方法我们对2010年1月至2022年6月在本中心经内镜诊断为SRUS并经组织病理学检查证实的所有患者进行回顾性分析。检索到的数据包括SRUS患者的人口学细节、临床特征以及内窥镜和组织病理学结果。结果纳入132例SRUS患者,平均(±标准差)年龄为45(±20.6)岁,男女比例为1.5:1。虽然大多数患者表现为症状组合,但最常见的临床表现是直肠出血(82%)。直肠溃疡,单发或多发,是内镜检查的主要表现,其次是息肉样病变。所有患者组织学均表现为纤维肌闭塞和隐窝扭曲。生物反馈训练、生活方式改变和硫糖钠灌肠在6周结束时约87%的患者成功,在12周结束时约76%的患者成功,其中2例患者进行了直肠脱垂手术。结论SRUS表现出多种症状,需要治疗医师高度怀疑。在我们的研究中最常见的症状是直肠出血;溃疡,单发或多发,溃疡,单发或多发,是最常见的内镜检查结果。内窥镜检查和组织病理学证实了诊断。
{"title":"Clinical, Endoscopic, and Histologic Characteristics of Patients with Solitary Rectal Ulcer Syndrome at a Tertiary Care Center","authors":"Syed Shafiq","doi":"10.1055/s-0043-1770922","DOIUrl":"https://doi.org/10.1055/s-0043-1770922","url":null,"abstract":"Abstract Objective Solitary rectal ulcer syndrome (SRUS) is a chronic disorder of defecation presenting with bleed per rectum, mucorrhea, tenesmus, perianal discomfort, etc. We aim to report clinical, endoscopic, and histologic features of SRUS in patients who underwent either colonoscopy or sigmoidoscopy at our center. Materials and Methods We performed retrospective analysis of all patients diagnosed with SRUS on endoscopy and confirmed by histopathologic examination at our center between January 2010 and June 2022. Data retrieved included demographic details, clinical features along with endoscopic, and histopathological findings of SRUS patients. Results The study included 132 patients with SRUS with mean (± standard deviation) age of 45 (± 20.6) years and male to female ratio of 1.5:1. While most of the patients presented with a combination of symptoms, the most common clinical presentation was bleeding per rectum (82%). Rectal ulcers, either single or multiple, were the predominant findings on endoscopy followed by polypoidal lesions. Histology showed fibromuscular obliteration and crypt distortion in all patients. Biofeedback training, lifestyle changes, and sucralfate enema were successful in about 87% of the patients at the end of 6 weeks and about 76% at the end of 12 weeks with surgery for rectal prolapse being performed in two of our patients. Conclusion SRUS presents with a myriad of symptoms and requires a high index of suspicion by the treating physician(s). While the most common presenting symptom in our study was rectal bleed rectal bleed; ulcers, either solitary or multiple, ulcers, either solitary or multiple, were the commonest endoscopy findings. Endoscopic findings along with histopathology confirm the diagnosis.","PeriodicalId":43098,"journal":{"name":"Journal of Digestive Endoscopy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135735328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of Endoscopic Biliary Drainage in Postsurgical Anatomy Using Endoscopic Ultrasound and Enteroscopy: A Comparative Study 内镜下胆道引流在超声内镜与肠镜下术后解剖中的效果比较研究
Pub Date : 2023-09-01 DOI: 10.1055/s-0043-1775861
Kapil Dev Jamwal, Atul Sharma, Rajesh Kumar Padhan, Manoj Kumar Sharma
Abstract Objectives Biliary obstruction is a common problem encountered in postsurgical anatomy, which may lead to serious complications if not treated promptly. Endoscopic drainage is a minimally invasive and effective treatment option for such patients. However, the optimal route of endoscopic drainage, either SBE-ERCP (single-balloon enteroscopy with endoscopic retrograde cholangiopancreatography) or EUS-BD (endoscopic ultrasound-guided bile duct drainage), remains controversial. In this study, we aim to evaluate the feasibility and outcomes of endoscopic drainage using these two techniques in postsurgical biliary obstruction over a period of 7 years. Materials and Methods We conducted a retrospective study of patients who underwent endoscopic drainage for postsurgical biliary obstruction using SBE-ERCP or EUS-BD techniques between 2015 and 2022. The demographic details, clinical presentation, procedure duration, number of sessions required, technical success, complications, and change of procedure from SBE-ERCP to EUS-BD or vice versa were recorded. Results Seventy-five patients, predominantly females with a mean age of 48 years, underwent endoscopic drainage. Forty-eight patients underwent SBE drainage and 27 patients underwent EUS-HG (EUS-guided hepaticogastrostomy). The mean duration of procedure (44 vs. 77 minutes), number of complications (4 vs. 5), technical success rate (93.5 vs. 85%), change of procedure (0 vs. 3), and number of sessions (1.1 vs. 1.8) were significantly less in the EUS-HG as compared to SBE-ERCP. Conclusions Endoscopic biliary drainage is feasible, safe, and effective in postsurgical biliary anatomy but requires high technical expertise. The study proposes an algorithm that can be applied in such group of patients to determine the route for choosing the drainage procedure. This requires further validation with a large prospective cohort.
摘要目的胆道梗阻是术后解剖中常见的问题,如果不及时治疗,可能会导致严重的并发症。内镜下引流是一种微创、有效的治疗方法。然而,内镜下引流的最佳途径是SBE-ERCP(单球囊肠镜内镜逆行胆管造影)还是EUS-BD(超声内镜引导胆管引流)仍存在争议。在这项研究中,我们的目的是评估在7年的时间里使用这两种技术在术后胆道梗阻的内镜下引流的可行性和结果。材料和方法我们对2015年至2022年期间采用SBE-ERCP或EUS-BD技术进行术后胆道梗阻内镜引流的患者进行了回顾性研究。记录了人口统计学细节、临床表现、手术时间、所需疗程数、技术成功、并发症以及从SBE-ERCP到EUS-BD或反之亦然的手术改变。结果75例患者行内镜下引流术,主要为女性,平均年龄48岁。48例患者行SBE引流,27例患者行EUS-HG (eus引导下肝胃造口术)。与SBE-ERCP相比,EUS-HG的平均手术时间(44分钟vs. 77分钟)、并发症数量(4分钟vs. 5分钟)、技术成功率(93.5 vs. 85%)、手术改变(0 vs. 3)和手术次数(1.1 vs. 1.8)显著少于SBE-ERCP。结论内镜下胆道引流术在胆道术后解剖中是可行、安全、有效的,但对技术要求较高。本研究提出了一种算法,可应用于这类患者,以确定选择引流手术的路径。这需要进一步的大规模前瞻性队列验证。
{"title":"Outcomes of Endoscopic Biliary Drainage in Postsurgical Anatomy Using Endoscopic Ultrasound and Enteroscopy: A Comparative Study","authors":"Kapil Dev Jamwal, Atul Sharma, Rajesh Kumar Padhan, Manoj Kumar Sharma","doi":"10.1055/s-0043-1775861","DOIUrl":"https://doi.org/10.1055/s-0043-1775861","url":null,"abstract":"Abstract Objectives Biliary obstruction is a common problem encountered in postsurgical anatomy, which may lead to serious complications if not treated promptly. Endoscopic drainage is a minimally invasive and effective treatment option for such patients. However, the optimal route of endoscopic drainage, either SBE-ERCP (single-balloon enteroscopy with endoscopic retrograde cholangiopancreatography) or EUS-BD (endoscopic ultrasound-guided bile duct drainage), remains controversial. In this study, we aim to evaluate the feasibility and outcomes of endoscopic drainage using these two techniques in postsurgical biliary obstruction over a period of 7 years. Materials and Methods We conducted a retrospective study of patients who underwent endoscopic drainage for postsurgical biliary obstruction using SBE-ERCP or EUS-BD techniques between 2015 and 2022. The demographic details, clinical presentation, procedure duration, number of sessions required, technical success, complications, and change of procedure from SBE-ERCP to EUS-BD or vice versa were recorded. Results Seventy-five patients, predominantly females with a mean age of 48 years, underwent endoscopic drainage. Forty-eight patients underwent SBE drainage and 27 patients underwent EUS-HG (EUS-guided hepaticogastrostomy). The mean duration of procedure (44 vs. 77 minutes), number of complications (4 vs. 5), technical success rate (93.5 vs. 85%), change of procedure (0 vs. 3), and number of sessions (1.1 vs. 1.8) were significantly less in the EUS-HG as compared to SBE-ERCP. Conclusions Endoscopic biliary drainage is feasible, safe, and effective in postsurgical biliary anatomy but requires high technical expertise. The study proposes an algorithm that can be applied in such group of patients to determine the route for choosing the drainage procedure. This requires further validation with a large prospective cohort.","PeriodicalId":43098,"journal":{"name":"Journal of Digestive Endoscopy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135735329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Unusual Presentation of Accidental Rectal Corrosive Injury 意外直肠腐蚀性损伤的罕见表现
Pub Date : 2023-09-01 DOI: 10.1055/s-0043-1775852
Maitrey Patel, Rushil Solanki, Radhika Chavan, Sanjay Rajput
Abstract Rectal corrosive injuries occur rarely among adult patients and are confined to suicidal patients and cases of homicide. These injuries are less frequently accidental. No reports of rectal corrosive injury have been reported in the literature to date. In this study, we report an unusual presentation of a very rare case of accidental rectal corrosive injury.
直肠腐蚀性损伤在成人患者中很少发生,仅限于自杀患者和他杀病例。这些伤害很少是意外的。迄今为止,文献中尚未报道直肠腐蚀性损伤。在这项研究中,我们报告了一个非常罕见的意外直肠腐蚀性损伤病例的不寻常的表现。
{"title":"An Unusual Presentation of Accidental Rectal Corrosive Injury","authors":"Maitrey Patel, Rushil Solanki, Radhika Chavan, Sanjay Rajput","doi":"10.1055/s-0043-1775852","DOIUrl":"https://doi.org/10.1055/s-0043-1775852","url":null,"abstract":"Abstract Rectal corrosive injuries occur rarely among adult patients and are confined to suicidal patients and cases of homicide. These injuries are less frequently accidental. No reports of rectal corrosive injury have been reported in the literature to date. In this study, we report an unusual presentation of a very rare case of accidental rectal corrosive injury.","PeriodicalId":43098,"journal":{"name":"Journal of Digestive Endoscopy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135735943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gastrointestinal Subepithelial Lesions: A Review 胃肠道上皮下病变:综述
IF 0.7 Pub Date : 2023-06-01 DOI: 10.1055/s-0043-1770923
S. Pal, Digvijay S. Hodgar
Abstract Submucosal lesions, also known as subepithelial lesions, are often encountered during endoscopy of the gastrointestinal tract. Most of the lesions are asymptomatic and can be diagnosed by routine endoscopic ultrasonography. Few lesions like gastrointestinal submucosal tumors (GIST) and leiomyoma require biopsy/fine-needle aspiration cytology (FNAC) for differentiation. Lesions like neuroendocrine tumors can be diagnosed by deep endoscopic biopsy as they originate from the inner mucosal layer. Management depends on the size and layer of origin of the lesion. Smaller lesions can be removed by endoscopic procedures and bigger lesions by surgery. Smaller lesions can be safely surveilled.
摘要粘膜下病变,也称为上皮下病变,在胃肠道内窥镜检查中经常会遇到。大多数病变是无症状的,可以通过常规内镜超声诊断。胃肠道黏膜下肿瘤(GIST)和平滑肌瘤等少数病变需要活检/细针穿刺细胞学(FNAC)进行鉴别。神经内分泌肿瘤等病变可通过深层内镜活检进行诊断,因为它们起源于内粘膜层。治疗取决于病变的大小和起源层。较小的病变可以通过内窥镜手术切除,较大的病变可以手术切除。可以安全地监测较小的病变。
{"title":"Gastrointestinal Subepithelial Lesions: A Review","authors":"S. Pal, Digvijay S. Hodgar","doi":"10.1055/s-0043-1770923","DOIUrl":"https://doi.org/10.1055/s-0043-1770923","url":null,"abstract":"Abstract Submucosal lesions, also known as subepithelial lesions, are often encountered during endoscopy of the gastrointestinal tract. Most of the lesions are asymptomatic and can be diagnosed by routine endoscopic ultrasonography. Few lesions like gastrointestinal submucosal tumors (GIST) and leiomyoma require biopsy/fine-needle aspiration cytology (FNAC) for differentiation. Lesions like neuroendocrine tumors can be diagnosed by deep endoscopic biopsy as they originate from the inner mucosal layer. Management depends on the size and layer of origin of the lesion. Smaller lesions can be removed by endoscopic procedures and bigger lesions by surgery. Smaller lesions can be safely surveilled.","PeriodicalId":43098,"journal":{"name":"Journal of Digestive Endoscopy","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48512255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Digestive Endoscopy
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1