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Gastrointestinal Subepithelial Lesions: A Review 胃肠道上皮下病变:综述
IF 0.7 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2023-06-01 DOI: 10.1055/s-0043-1770923
S. Pal, Digvijay S. Hodgar
Abstract Submucosal lesions, also known as subepithelial lesions, are often encountered during endoscopy of the gastrointestinal tract. Most of the lesions are asymptomatic and can be diagnosed by routine endoscopic ultrasonography. Few lesions like gastrointestinal submucosal tumors (GIST) and leiomyoma require biopsy/fine-needle aspiration cytology (FNAC) for differentiation. Lesions like neuroendocrine tumors can be diagnosed by deep endoscopic biopsy as they originate from the inner mucosal layer. Management depends on the size and layer of origin of the lesion. Smaller lesions can be removed by endoscopic procedures and bigger lesions by surgery. Smaller lesions can be safely surveilled.
摘要粘膜下病变,也称为上皮下病变,在胃肠道内窥镜检查中经常会遇到。大多数病变是无症状的,可以通过常规内镜超声诊断。胃肠道黏膜下肿瘤(GIST)和平滑肌瘤等少数病变需要活检/细针穿刺细胞学(FNAC)进行鉴别。神经内分泌肿瘤等病变可通过深层内镜活检进行诊断,因为它们起源于内粘膜层。治疗取决于病变的大小和起源层。较小的病变可以通过内窥镜手术切除,较大的病变可以手术切除。可以安全地监测较小的病变。
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引用次数: 0
Endoscopic Management of Pediatric Foreign Body Ingestions and Food Bolus Impactions: A Retrospective Study from a Tertiary Care Center 儿科异物摄入和食物栓塞的内镜治疗:一项来自三级护理中心的回顾性研究
IF 0.7 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2023-06-01 DOI: 10.1055/s-0043-1771009
S. Shafiq, H. Devarbhavi
Abstract Background  Foreign body (FB) ingestion is a common pediatric problem with the majority of these occurring in children younger than 3 years. Management varies depending on the age of the patient, ingested object(s), its location along the digestive tract, and the available expertise. We aim to report our experience with endoscopic management of FB ingestions in children (<18 years). Materials and Methods  We retrospectively reviewed and analyzed endoscopic and medical records from our hospital database of all pediatric patients (<18 years) who presented with FB ingestion between January 2011 and December 2021. Results  Our analysis included a total of 368 patients. FB ingestions and/or food bolus impactions were noted in 242 and 11 children, respectively while 115 (31.25%) had spontaneously passed off FB from the digestive tract. Most common FB was coin (28.5%) followed by animal bones (26.2%). Endoscopic management of FBs and food bolus impaction was successful in 247 children (97.63%), while endoscopic FB retrieval failed in 6 children including 1 with fish bone and 5 with button batteries. A total of 9 out of 11 children with food bolus impaction had underlying esophageal pathology, the commonest being corrosive stricture ( n  = 7). No mortality related to endoscopic intervention was reported. Conclusions  Endoscopic retrieval of ingested FBs and food bolus impaction in children is a safe and effective approach when performed by experienced endoscopists and is associated with a high success rate and a lower incidence of complications with reduced hospital stay.
摘要背景 异物(FB)摄入是一个常见的儿科问题,其中大多数发生在3岁以下的儿童身上。根据患者的年龄、摄入的物体、其在消化道中的位置以及可用的专业知识,管理方式各不相同。我们的目的是报告我们对儿童(<18岁)FB摄入的内镜管理经验。材料和方法 我们回顾性地回顾和分析了我们医院数据库中2011年1月至2021年12月期间出现FB摄入的所有儿科患者(<18岁)的内镜和医疗记录。后果 我们的分析共包括368名患者。242名和11名儿童分别出现FB摄入和/或食物团堵塞,115名(31.25%)儿童自发从消化道排出FB。最常见的FB是硬币(28.5%),其次是动物骨骼(26.2%)。247名儿童(97.63%)成功地进行了FBs和食物团嵌塞的内镜治疗,而6名儿童(包括1名鱼骨和5名纽扣电池)失败。在11例食物团嵌塞患儿中,共有9例有潜在的食管病理,最常见的是腐蚀性狭窄(n = 7) 。未报告与内镜干预相关的死亡率。结论 由经验丰富的内窥镜医生对儿童摄入的FBs和食物团嵌塞进行内窥镜取出是一种安全有效的方法,并且与高成功率和低并发症发生率以及减少住院时间有关。
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引用次数: 0
Gastroduodenal Intussusception Due to Gastric GIST Presenting with Melena 胃间质瘤引起的胃十二指肠肠套叠伴黑黑
IF 0.7 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2023-06-01 DOI: 10.1055/s-0042-1757471
A. Jain, Sudesh Sharda, Suchita Jain, A. Singh, Shohini Sircar, Priyanka Bhagat, Tasvir Balar
Abstract Intussusception rarely occurs among adult patients; however, gastroduodenal intussusception is the most infrequent form of intussusception in adults. Almost all these patients present with abdominal pain and vomiting with or without associated gastrointestinal bleed. But none of the patients reported in the literature have presented with gastrointestinal bleed alone. We report a case of gastroduodenal intussusception who presented with melena alone without abdominal pain and vomiting.
摘要肠套叠在成年患者中很少发生;然而,胃十二指肠肠套叠是成人肠套叠中最罕见的形式。几乎所有这些患者都表现为腹痛和呕吐,伴有或不伴有胃肠道出血。但文献中没有一例患者单独出现胃肠道出血。我们报告一例胃十二指肠肠套叠,仅以黑便表现,无腹痛和呕吐。
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引用次数: 0
Endoscopic Ultrasound Made Easy 内镜超声变得简单
IF 0.7 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2023-06-01 DOI: 10.1055/s-0043-1772235
S. Varadarajulu
Learning endoscopic ultrasound (EUS) can be challenging as the technology combines the disciplines of flexible endoscopy and diagnostic radiology. In the early days of evolution, radiographers performed EUS independently and taught gastroenterologists the basic principles of ultrasound. Lok Tio developed the first learning tool—an atlas of EUS—by correlating EUS images with computed tomography, surgery, and pathology. Robert Hawes is creditedwith developing the “station-based approach” whereby a gastroenterologist learnt how to position the EUS transducer at specific anatomical locations in the gastrointestinal tract and then identify the surrounding organs sonographically. This was the sentinel step that simplified learning and training in EUS. Diagnostic EUS is mostly practiced for staging tumors and performing tissue acquisition. These carry significant implications for patient management and clinical outcomes. To achieve optimal outcomes, it is not sufficient to just know how to do EUS; one needs to be proficient. However, learning a technology is very different from mastering the discipline. Societies such as the ASGE (United States) and FOCUS (Canadian) have developed minimum thresholds to assess competency, and the number of procedures vary from 225 to 250. However, there is significant subjectivity between learners and one rule does not fit all. More importantly, learning EUS has two components: technical and cognitive. In addition to performing the procedure independently, the endoscopist must possess sufficient cognitive skills to formulate the derived information to executable treatment plan. Both components are not mutually exclusive—they are complimentary/mandatory. New training tools such as TEESAT (The EUS and ERCP Skills Assessment Tool) emphasize these principles in EUS learning. In this edition of the journal, Chavan and Rajput have proposed a pictorial essay to make EUS examination of the pancreas easier for the novice endosonographer. They have focused on the most difficult aspect of EUS—pancreatic anatomy—and have simplified it. The authors have expanded on the station-based approach by paying particular attention to technical nuances that can facilitate better interrogation of various parts of the pancreas, surrounding vasculature, and adjacent organs. The imagesandaccompanying videosare thoroughand easy to comprehend. This should enable precise detection and accurate staging of pancreatic diseases. This pictorial essaywill be of significant relevance to novices, particularly those bereft of hands-on training opportunities. The onus is now on apprentices to apply this knowledge clinically and develop the requisite cognitive skills so that theycangainproficiency in the immediate future and attain mastery with time.
学习内窥镜超声(EUS)可能具有挑战性,因为该技术结合了柔性内窥镜和诊断放射学的学科。在进化的早期,放射技师独立进行EUS,并教授胃肠病学家超声波的基本原理。Lok Tio通过将EUS图像与计算机断层扫描、手术和病理学相关联,开发了第一个学习工具——EUS图谱。Robert Hawes开发了“基于位置的方法”,通过该方法,胃肠病学家学会了如何将EUS换能器定位在胃肠道的特定解剖位置,然后通过超声波识别周围器官。这是简化EUS学习和培训的关键步骤。诊断性EUS主要用于肿瘤分期和组织采集。这些对患者管理和临床结果具有重要意义。为了实现最佳结果,仅仅知道如何进行EUS是不够的;一个人需要精通。然而,学习一项技术与掌握这门学科是非常不同的。ASGE(美国)和FOCUS(加拿大)等协会制定了评估能力的最低阈值,程序数量从225到250不等。然而,学习者之间存在着显著的主观性,一条规则并不适合所有人。更重要的是,学习EUS有两个组成部分:技术和认知。除了独立执行手术外,内窥镜医生还必须具备足够的认知技能,以制定可执行治疗计划的衍生信息。这两个组成部分并不相互排斥——它们是互补的/强制性的。TEESAT(EUS和ERCP技能评估工具)等新的培训工具在EUS学习中强调了这些原则。在本期杂志中,Chavan和Rajput提出了一篇图片文章,让新手内镜医生更容易对胰腺进行EUS检查。他们专注于EUS最困难的方面——胰腺解剖——并对其进行了简化。作者对基于工作站的方法进行了扩展,特别注意技术上的细微差别,这有助于更好地询问胰腺的各个部位、周围血管系统和邻近器官。图片和随附的视频都很全面,很容易理解。这应该能够准确地检测和分期胰腺疾病。这篇图片文章将对新手,特别是那些失去实践培训机会的新手具有重要意义。现在,学徒们有责任将这些知识应用到临床上,并发展必要的认知技能,以便在不久的将来获得熟练掌握,并随着时间的推移获得熟练掌握。
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引用次数: 0
Risk Factors for Bleeding during Endoscopic Necrosectomy: Are We Wiser Now? 内镜下坏死切除术出血的危险因素:我们现在更明智了吗?
IF 0.7 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2023-06-01 DOI: 10.1055/s-0043-1766121
Anurag Sachan, S. Rana
Abstract Endoscopic necrosectomy (EN) in acute necrotizing pancreatitis has mortality benefits and may avert the requirement for surgery. However, bleeding is a common adverse event during EN. There is limited knowledge about the risk factors predicting this adverse event and the measures for its management. In this news and views, we discuss recently published studies that evaluated the risk factors for bleeding during EN.
摘要内镜下坏死切除术(EN)治疗急性坏死性胰腺炎具有死亡率优势,可以避免手术。然而,出血是EN期间常见的不良事件。对预测该不良事件的风险因素及其管理措施的了解有限。在这篇新闻和观点中,我们讨论了最近发表的评估EN期间出血风险因素的研究。
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引用次数: 0
Pictorial Essay of Linear Endoscopic Ultrasound Examination of Pancreas Anatomy 胰腺解剖线性超声内镜检查论文集
IF 0.7 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2023-06-01 DOI: 10.1055/s-0043-1770924
R. Chavan, S. Rajput
Abstract Endoscopic ultrasound (EUS) is a widely used imaging modality for both diagnostic and therapeutic purposes. Understanding the anatomy is crucial during a curved linear EUS examination. Compared with other advanced endoscopic techniques, the learning curve for EUS is longer, and the training facilities for EUS are also not widely available. The interest and enthusiasm for EUS among endoscopists is limited by the long learning curve and the scarcity of training programs. Imaging of the pancreas is the most common indication of EUS examination, and many endoscopist often face difficulty in understanding the anatomy and orientation of the pancreas on linear EUS examination. In this article, we will discuss the problems encountered during linear EUS examination and how to overcome each problem with a station-wise pancreas examination.
超声内镜(EUS)是一种广泛应用于诊断和治疗的成像方式。在弯曲线性EUS检查中,了解解剖结构是至关重要的。与其他先进的内镜技术相比,EUS的学习曲线更长,培训设施也不广泛。内窥镜医师对EUS的兴趣和热情受到长期学习曲线和缺乏培训计划的限制。胰腺成像是EUS检查最常见的指征,许多内镜医师在线性EUS检查中往往难以理解胰腺的解剖结构和方向。在本文中,我们将讨论线性EUS检查中遇到的问题,以及如何通过站位胰腺检查克服这些问题。
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引用次数: 1
Peroral Endoscopic Myotomy (POEM) in a 19-Month-Old Girl with Primary Achalasia 经口内窥镜下肌切开术治疗原发性失弛缓症1例
IF 0.7 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2023-06-01 DOI: 10.1055/s-0043-1769926
Serkan Duman, A. Yurçi, J. Cho
Abstract Introduction  Primary achalasia is an idiopathic motility disorder of the esophagus characterized by esophageal aperistalsis and incomplete relaxation of the lower esophageal sphincter (LES) in response to swallowing. The gold standard diagnostic method in adults is high-resolution manometry (HRM). Diagnostic criteria in adults are also used in children, but some HRM normal values may change depending on age. Case Report  A 15-month-old girl was admitted to the hospital for evaluation due to persistent vomiting since birth. Vomiting included what she ate regardless of the amount of food she consumed. Barium esophagography revealed barium retention, esophageal dilatation, and a “bird's beak appearance” in the distal esophagus. Esophagogastroduodenoscopy revealed stenosis in the lower esophagus and bubbles at the esophagogastric junction. In HRM, the resting LES pressure was 43.4 mm Hg, there was pan-esophageal pressurization with 60% of swallows and no normal peristalsis. The patient was diagnosed with type II achalasia based on the Chicago 3.0 classification. First, the tube was inserted to ensure adequate nutrition of the patient, and approximately 4 months later, when the patient was 10 kg, the peroral endoscopic myotomy (POEM) procedure was performed. No complications developed during and after the procedure. At the 6th month after treatment, the patient was completely asymptomatic and her weight was within normal limits for her age. Conclusion  POEM is an effective and safe method in the treatment of pediatric patients with idiopathic achalasia.
摘要简介 原发性贲门失弛缓症是一种特发性食管运动障碍,其特征是食道蠕动障碍和吞咽时食管下括约肌(LES)不完全松弛。成人的金标准诊断方法是高分辨率测压(HRM)。成人的诊断标准也适用于儿童,但一些HRM正常值可能会随着年龄的变化而变化。案例报告 一名15个月大的女孩因出生后持续呕吐入院接受评估。呕吐包括她吃了什么,不管她吃了多少食物。钡食道造影显示钡滞留,食道扩张,食道远端出现“鸟喙状”。食管-胃十二指肠镜检查显示食管下段狭窄,食管-胃交界处有气泡。在HRM中,静息LES压力为43.4 毫米汞柱,60%的燕子进行了全食道加压,没有正常的蠕动。根据Chicago 3.0分类,该患者被诊断为II型贲门失弛缓症。首先,插入导管以确保患者有足够的营养,大约4个月后,当患者10岁时 kg,进行经口内镜肌切开术(POEM)。术中及术后均未出现并发症。在治疗后的第6个月,患者完全没有症状,她的体重在年龄的正常范围内。结论 POEM是治疗儿童特发性贲门失弛缓症的一种有效且安全的方法。
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引用次数: 0
Society of Gastrointestinal Endoscopy of India Consensus Guidelines on Endoscopic Ultrasound-Guided Biliary Drainage: Part II (Technical Aspects) 印度胃肠内镜学会超声内镜引导胆道引流共识指南:第二部分(技术方面)
IF 0.7 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2023-04-24 DOI: 10.1055/s-0043-1768043
J. Samanta, P. Udawat, S. Chowdhary, D. Gunjan, P. Rai, V. Bhatia, Vikas Singla, Saurabh S. Mukewar, Nilay Mehta, C. Achanta, A. Dalal, M. Sahu, A. Balekuduru, Abhijith Bale, Jahangir Basha, M. Philip, S. Rana, R. Puri, S. Lakhtakia, V. Dhir
Abstract Endoscopic management of bile duct obstruction is a key aspect in gastroenterology practice and has evolved since the first description of biliary cannulation by McCune et al in 1968. Over many decades, the techniques and accessories have been refined, and currently, the first-line management for extrahepatic biliary obstruction is endoscopic retrograde cholangiopancreatography (ERCP). However, even in expert hands, the success rate of ERCP reaches up to 95%. In almost 4 to 16% cases, failure to cannulate the bile duct may necessitate other alternatives such as surgical bypass or, more commonly, percutaneous transhepatic biliary drainage (PTBD). While surgery is associated with high morbidity and mortality, PTBD has a very high reintervention and complication rate (∼80%) and poor quality of life. Almost parallelly, endoscopic ultrasound (EUS) has come a long way from a mere diagnostic tool to a substantial therapeutic option in various pancreaticobiliary diseases. Biliary drainage using EUS-guidance (EUS-BD) has gained momentum since the first report published by Giovannini et al in 2001. The concept of accessing the bile duct through a different route than the papilla, circumventing the shortcomings of PTBD, and sometimes bypassing the actual obstruction have enthused a lot of interest in this novel strategy. The three key methods of EUS-BD entail transluminal, antegrade, and rendezvous approach. Over the past decade, with growing experience, EUS-BD has been found to be equivalent to ERCP or PTBD for malignant obstruction with better success rates. EUS-BD, however, is not devoid of adverse events and can carry fatal adverse events. However, neither the technique of EUS-BD nor the accessories and stents for EUS-BD have been standardized. Additionally, different countries and regions have different availability of the accessories, making generalizability a difficult task. Thus, technical aspects of this evolving therapy need to be outlined. For these reasons, Society of Gastrointestinal Endoscopy of India (SGEI) deemed it appropriate to develop technical consensus statements for performing safe and successful EUS-BD.
摘要胆管梗阻的内窥镜治疗是胃肠病实践中的一个关键方面,自1968年McCune等人首次描述胆道插管以来,该方法一直在发展。几十年来,技术和附件已经得到了改进,目前,肝外胆管梗阻的一线治疗是内镜逆行胰胆管造影(ERCP)。然而,即使在专家手中,ERCP的成功率也高达95%。在几乎4%至16%的病例中,未能插管胆管可能需要其他替代方案,如手术旁路或更常见的经皮肝穿刺胆道引流(PTBD)。虽然手术与高发病率和死亡率有关,但PTBD的再干预和并发症发生率非常高(~80%),生活质量较差。几乎同时,内镜超声(EUS)已经从一种简单的诊断工具发展成为各种胰胆管疾病的重要治疗选择。自Giovannini等人于2001年发表第一份报告以来,使用EUS指导的胆道引流(EUS-BD)已经获得了发展势头。通过与乳头不同的途径进入胆管,绕过PTBD的缺点,有时绕过实际的梗阻,这一概念激发了人们对这种新策略的兴趣。EUS-BD的三种关键方法包括经腔、顺行和交会进近。在过去的十年里,随着经验的积累,EUS-BD在治疗恶性梗阻方面与ERCP或PTBD相当,成功率更高。然而,EUS-BD并非没有不良事件,并且可能携带致命的不良事件。然而,无论是EUS-BD的技术,还是EUS-BD配件和支架,都没有标准化。此外,不同的国家和地区有不同的配件供应,这使得推广成为一项困难的任务。因此,需要概述这种不断发展的疗法的技术方面。出于这些原因,印度胃肠道内窥镜学会(SGEI)认为制定安全成功的EUS-BD的技术共识声明是合适的。
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引用次数: 2
T-piece Traction Removal for Buried Bumper Syndrome t片牵引移除治疗埋藏保险杠综合征
IF 0.7 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2023-04-20 DOI: 10.1055/s-0043-1768044
V. Zimmer
Percutaneous endoscopic gastrostomy (PEG) has become the standard nutrition access with well-established procedural and long-term safety data. Yet, buried bumper syndrome (BBS) remains a major concern and complicates up to 5% of PEGs. Albeit poorly standardized, endoscopicmanagement is possible in most internal disc migrations with variable tractionor dissection-based techniques available. Most advanced BBS stages>Cyrany stage 2 call for incision of hyperplastic tissue overgrowth due to insufficient traction forces for nondissection extraction.1 A 54-year-old institutionalized male patient suffering from cerebral palsy dependent on enteral nutrition presented with suspicion of BBS due to insufficient PEG forward mobility, with tube patency maintained. BBS was confirmed using computed tomography, in addition and compatible with laboratory signs of systemic inflammation, suggesting a small intramural abscess. After institution of broad-spectrum antibiotics, the patient underwent upper endoscopy the following day with the internal disc not visible. Instead, an elevated lesion reminiscent of a submucosal tumor with central putrid discharge emerged (►Fig. 1A). However, given adequate internal drainage, no specific treatment was needed beyond antibiotic treatment. After adequate washing, the abscess cavity could be entered with the scope tip with gentle pressure and the disc was visualized (►Fig. 1B). Next, the external tube length was reduced, and a standard biopsy forceps advanced through the tube (►Fig. 1C). A polypectomy snare was advanced through the endoscope, opened and grasped by the forceps (►Fig. 1D). An estimated 3-cm piece, the fashioned T-piece, was cut from the tube and externally grasped by the snare (compare ►Fig. 1E). Beforehand, a nylon thread from a commercially available PEG tube set was tied to the tube and pulled into the stomach along with the tube system withdrawn into the stomach. Alternatively, the nylon thread might have been placed through the indwelling PEG tube beforehand. After repeat endoscopy of the intramural cavity, a new PEG was inserted in the pull technique (►Fig. 1F; ►Video 1). Concerning chances of migration of the newly placed PEG tube as it has been placed in the same area, in fact, there are no specific data available for this critical issue. However, in the author’s opinion, migration and/or BBS are rather a question of proper PEG care by well-trained nurses rather than a question of endoscopy technique and/or tactics.
经皮内镜胃造口术(PEG)已成为标准的营养途径,具有完善的程序和长期安全性数据。然而,隐性保险杠综合征(BBS)仍然是一个主要问题,并使高达5%的PEG复杂化。尽管标准化较差,但在大多数椎间盘内移行中,内窥镜管理是可行的,可采用基于可变牵引或解剖的技术。大多数晚期BBS分期>Cyrany 2期要求切开增生组织过度生长,因为非剖切提取的牵引力不足。1一名54岁的住院男性患者患有依赖肠内营养的脑瘫,由于PEG向前移动能力不足,怀疑患有BBS,并保持管道通畅。BBS通过计算机断层扫描得到证实,此外,BBS与全身炎症的实验室体征一致,表明有一个小的壁内脓肿。在服用广谱抗生素后,患者第二天接受了上内窥镜检查,椎间盘不可见。相反,出现了一个升高的病变,让人想起粘膜下肿瘤,伴有中央腐烂分泌物(►图1A)。然而,如果有足够的内部引流,除了抗生素治疗外,不需要任何特定的治疗。在充分冲洗后,可以用镜尖轻轻按压进入脓肿腔,并观察椎间盘(►图1B)。接下来,外管长度缩短,标准活检钳穿过外管(►图1C)。通过内窥镜推进息肉切除圈套器,打开并用钳子夹住(►图1D)。从导管上切下一块大约3厘米的T形块,并用圈套器从外部抓住(比较►图1E)。在此之前,将市售PEG导管组的尼龙线系在导管上,并将导管系统拉入胃中。或者,尼龙线可以预先穿过留置的PEG管。在反复对壁内腔进行内窥镜检查后,在牵拉技术中插入新的PEG(►图1F;►视频1)。关于新放置的PEG管被放置在同一区域时的迁移机会,事实上,没有关于这一关键问题的具体数据。然而,在作者看来,迁移和/或BBS是一个由训练有素的护士进行适当PEG护理的问题,而不是内窥镜检查技术和/或策略的问题。
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引用次数: 0
Society of Gastrointestinal Endoscopy of India Consensus Guidelines on Endoscopic Ultrasound-Guided Biliary Drainage: Part I (Indications, Outcomes, Comparative Evaluations, Training) 印度胃肠道内窥镜学会内镜超声引导胆道引流共识指南:第一部分(适应症、结果、比较评估、培训)
IF 0.7 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2023-03-01 DOI: 10.1055/s-0043-1761591
P. Rai, P. Udawat, S. Chowdhary, D. Gunjan, J. Samanta, V. Bhatia, Vikas Singla, Saurabh S. Mukewar, Nilay Mehta, C. Achanta, A. Dalal, M. Sahu, A. Balekuduru, Abhijith Bale, Jahangir Basha, M. Philip, S. Rana, R. Puri, S. Lakhtakia, V. Dhir
Abstract Endoscopic management of bile duct obstruction is a key aspect in gastroenterology practice and has evolved since the first description of biliary cannulation by McCune et al in 1968. Over many decades, the techniques and accessories have been refined and currently, the first-line management for extrahepatic biliary obstruction is endoscopic retrograde cholangiopancreaticography (ERCP). However, even in expert hands the success rate of ERCP reaches up to 95%. In almost 4 to 16% cases, failure to cannulate the bile duct may necessitate other alternatives such as surgical bypass or more commonly percutaneous transhepatic biliary drainage (PTBD). While surgery is associated with high morbidity and mortality, PTBD has a very high reintervention and complication rate (∼80%) and poor quality of life. Almost parallelly, endoscopic ultrasound (EUS) has come a long way from a mere diagnostic tool to a substantial therapeutic option in various pancreatico-biliary diseases. Biliary drainage using EUS-guidance (EUS-BD) has gained momentum since the first report published by Giovannini et al in 2001. The concept of accessing the bile duct through a different route than the papilla, circumventing the shortcomings of PTBD and sometimes bypassing the actual obstruction have enthused a lot of interest in this novel strategy. The three key methods of EUS-BD entail transluminal, antegrade, and rendezvous approach. Over the past decade, with growing experience, EUS-BD has been found to be equivalent to ERCP or PTBD for malignant obstruction with better success rates. EUS-BD, albeit, is not devoid of adverse events and can carry fatal adverse events. However, neither the technique of EUS-BD, nor the accessories and stents for EUS-BD have been standardized. Additionally, different countries and regions have different availability of the accessories making generalizability a difficult task. Thus, technical aspects of this evolving therapy need to be outlined. For these reasons, the Society of Gastrointestinal Endoscopy India deemed it appropriate to develop technical consensus statements for performing safe and successful EUS-BD.
摘要胆管梗阻的内窥镜治疗是胃肠病实践中的一个关键方面,自1968年McCune等人首次描述胆道插管以来,该方法一直在发展。几十年来,技术和附件已经得到了改进,目前,肝外胆管梗阻的一线治疗是内镜逆行胰胆管造影(ERCP)。然而,即使在专家手中,ERCP的成功率也高达95%。在几乎4%至16%的病例中,未能插管胆管可能需要其他替代方案,如手术旁路或更常见的经皮肝穿刺胆道引流(PTBD)。虽然手术与高发病率和死亡率有关,但PTBD的再干预和并发症发生率非常高(~80%),生活质量较差。几乎同时,内镜超声(EUS)已经从一种简单的诊断工具发展成为各种胰胆管疾病的重要治疗选择。自Giovannini等人于2001年发表第一份报告以来,使用EUS指导的胆道引流(EUS-BD)已经获得了发展势头。通过与乳头不同的途径进入胆管,绕过PTBD的缺点,有时绕过实际的梗阻,这一概念激发了人们对这种新策略的兴趣。EUS-BD的三种关键方法包括经腔、顺行和交会进近。在过去的十年里,随着经验的积累,EUS-BD在治疗恶性梗阻方面与ERCP或PTBD相当,成功率更高。尽管如此,EUS-BD并非没有不良事件,并且可能携带致命的不良事件。然而,无论是EUS-BD技术,还是EUS-BD的附件和支架都没有标准化。此外,不同的国家和地区有不同的配件,这使得推广成为一项困难的任务。因此,需要概述这种不断发展的疗法的技术方面。出于这些原因,印度胃肠道内窥镜学会认为,为安全成功地进行EUS-BD制定技术共识声明是合适的。
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引用次数: 2
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Journal of Digestive Endoscopy
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