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Indian Survey on Management of Choledocholithiasis—Opportunities for Improvement and Future Studies 印度胆总管结石管理调查-改进的机会和未来的研究
IF 0.7 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2022-12-01 DOI: 10.1055/s-0042-1758533
N. Jagtap, Sudatta B Waghmare, S. Sundaram, Rohan Khairatkar, S. Modak, S. Lakhtakia, M. Tandan, G. Rao, D. Reddy
Abstract Background  In clinical practice, decision about management of choledocholithiasis is driven by availability of resources and expertise, patients and healthcare professional preferences. This survey is aimed to describe the approach of physicians and surgeons for the management of choledocholithiasis. Method  A 36-question online survey was conducted using Google Forms on various aspects of management of choledocholithiasis. Results  The responses from 323 participants were included, of which 202 (62.54%) were physicians and 121 (37.46%) were surgeons. The proportion of responders who do not follow American or European Society of Gastrointestinal Endoscopy guidelines is associated with increasing age and experience of responders ( p  = 0.0001), while place of work (private vs. teaching) and broad specialty (physician vs surgeon) are not associated ( p >0.05). For patients with high likelihood of choledocholithiasis, 123 (38.1%) participants prefer to do endoscopic ultrasound/magnetic resonance cholangiopancreatography (EUS/MRCP) rather than directly performing endoscopic retrograde cholangiopancreatography/intraoperative cholangiography (ERCP/IOC). For intermediate likelihood, MRCP is more commonly preferred compared with EUS, due to local availability (44%), expertise (39.6%), healthcare professionals preference (30.7%), and patients preference (17.3%). For difficult common bile duct (CBD) stones, short biliary sphincterotomy with large balloon sphincteroplasty (59.4%), followed by laparoscopic CBD exploration are commonly used approaches. Prophylactic CBD stent placement after ERCP and CBD clearance is common practice. Preoperative ERCP followed by cholecystectomy is more preferred approach than cholecystectomy and CBD exploration. Conclusion  There is considerable variability in the management of choledocholithiasis. The practices such as use of EUS/MRCP for high likelihood group, use of prophylactic CBD stent placement after ERCP and CBD clearance, and use of single stage approach especially in patient with intermediate likelihood group should be addressed in future studies.
摘要背景在临床实践中,胆总管结石的治疗决策受资源和专业知识的可用性、患者和医疗保健专业人员的偏好驱动。这项调查的目的是描述的方法的内科医生和外科医生的胆总管结石的管理。方法采用谷歌表格对胆总管结石的管理进行36题的在线调查。结果共纳入问卷323人,其中内科医生202人(62.54%),外科医生121人(37.46%)。不遵循美国或欧洲胃肠内窥镜学会指南的应答者比例与应答者年龄和经验的增加有关(p = 0.0001),而工作地点(私人与教学)和广泛的专业(内科医生与外科医生)无关(p >0.05)。对于胆总管结石的高可能性患者,123名(38.1%)参与者更倾向于内镜下超声/磁共振胆管造影(EUS/MRCP),而不是直接进行内镜下逆行胆管造影/术中胆管造影(ERCP/IOC)。对于中等可能性,MRCP比EUS更受欢迎,因为当地可用性(44%)、专业知识(39.6%)、医疗保健专业人员偏好(30.7%)和患者偏好(17.3%)。对于难治性胆总管结石,常采用短段胆道括约肌切开术联合大球囊括约肌成形术(59.4%),再行腹腔镜下胆总管探查。在ERCP和CBD清除后预防性放置CBD支架是常见的做法。术前ERCP加胆囊切除术优于胆囊切除术加CBD探查。结论胆总管结石的治疗存在很大差异。对于高似然组使用EUS/MRCP,在ERCP和CBD清除后使用预防性CBD支架,特别是在中似然组患者使用单期入路等做法,应在未来的研究中加以解决。
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引用次数: 0
Endoscopic Ultrasound-Guided Fine-Needle Biopsy for Pancreatic Lesions is the Way Forward: Here is the Evidence! 内镜超声引导下胰腺病变细针活检是前进的道路:以下是证据!
IF 0.7 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2022-09-01 DOI: 10.1055/s-0042-1748493
D. Jha, S. Rana
Endoscopic ultrasound-guided tissue acquisition (EUS TA) has increasingly become imperative for pancreatic pathology in arriving at the correct diagnosis because of its simplicity, cost-effectiveness, and availability at high-volume centers. The advent of EUS fine-needle biopsy (FNB) has revolutionized EUS TA by providing samples that are larger and more diagnostic compared with fine-needle aspiration (FNA). Rapid onsite evaluation (ROSE) has been conventionally used for improving the cytological yield as well as diagnostic accuracy of EUS FNA. The development of FNB has obviated the need for ROSE, and evidence from retrospective and comparative studies has suggested that FNB is as good as FNA with ROSE in terms of diagnostic accuracy and reduced costs. However, strong evidence in the form of a randomized controlled trial (RCT) was missing. In this news and views, we discuss a multicenter RCT that has compared the diagnostic accuracy of EUS FNB alone to EUS FNA with ROSE in patients with solid pancreatic lesions. This study has reemphasized that EUS FNB has a diagnostic accuracy comparable to EUS + ROSE at a comparable cost and requires fewer passes and has a shorter procedure time.
内镜超声引导的组织采集(EUS-TA)由于其简单、成本效益和在高容量中心的可用性,在胰腺病理学中获得正确诊断方面变得越来越重要。EUS细针活检(FNB)的出现使EUS TA发生了革命性的变化,与细针抽吸(FNA)相比,它提供了更大、更具诊断性的样本。快速现场评估(ROSE)通常用于提高EUS-FNA的细胞学产量和诊断准确性。FNB的发展消除了对ROSE的需求,回顾性和比较研究的证据表明,在诊断准确性和降低成本方面,FNB与带ROSE的FNA一样好。然而,缺乏随机对照试验(RCT)形式的有力证据。在这篇新闻和观点中,我们讨论了一项多中心随机对照试验,该试验比较了单纯EUS-FNB与EUS-FNA联合ROSE对胰腺实性病变患者的诊断准确性。这项研究再次强调,EUS FNB的诊断准确性与EUS相当 + ROSE的成本相当,需要更少的通道,手术时间更短。
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引用次数: 0
Future of Metabolic Endoscopy 代谢内窥镜的未来
IF 0.7 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2022-09-01 DOI: 10.1055/s-0042-1754335
Rabih Ghazi, E. Vargas, D. Abboud, Farah Abdul Razak, Tala Mahmoud, A. Storm, V. Chandrasekhara, B. A. Abu Dayyeh
Obesity has been escalating as one of the worst public health epidemics. Conservative therapies including lifestyle modifications and weight loss medications have limited efficacy and long-term sustainability. Bariatric surgeries, although effective, remain underutilized due to their cost, safety concerns, and patient acceptance. In the past two decades, endoscopic bariatric and metabolic therapies (EBMTs) have emerged as safe, effective, and less invasive options for the treatment of obesity and its comorbidities, with recent studies reporting favorable outcomes in terms of weight loss and metabolic parameters. This article reviews the major and newly developed EBMTs, with emphasis on their metabolic effects and potential use in the management of metabolic conditions.
肥胖已经成为最严重的公共卫生流行病之一。包括改变生活方式和减肥药物在内的保守疗法的疗效和长期可持续性有限。减肥手术虽然有效,但由于其成本、安全问题和患者接受度,仍然没有得到充分利用。在过去的二十年里,内镜减肥和代谢疗法(EBMT)已成为治疗肥胖及其合并症的安全、有效和微创的选择,最近的研究报告在减肥和代谢参数方面取得了良好的结果。本文综述了主要和新开发的EBMT,重点介绍了它们的代谢作用和在代谢状况管理中的潜在用途。
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引用次数: 0
Endocuff Vision to Improve Adenoma Vision: A Brief Overview endocff视力改善腺瘤视力:简要概述
IF 0.7 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2022-09-01 DOI: 10.1055/s-0042-1755338
J. Shukla, J. Samanta
Colorectal cancer (CRC)-related mortality can be reduced through screening and early detection. The aim of any CRC screening program is to detect as many adenomas/polyps in the early stage as possible and hence, adenoma detection rate (ADR) is a key quality indicator of colonoscopy. Various methods and techniques have been studied and developed over the years to improve the quality of colonoscopy and thereby increase ADR. This ranges from use of various regimens to improve bowel preparation, defining an optimum colonoscope withdrawal time for the operator, distal attachment caps, use of different wavelength of light, colonoscope with increased degree of view to the use of modern-day artificial intelligence to improve ADR. Of all the various measures, use of distal attachment device seems an easy, cheap and readily usable technique to increase real-time ADR. A variety of such devices have been evaluated over time starting from simple transparent caps, EndoRings, Endocuff to Endocuff Vision for their effectiveness. In this review, we have provided a brief description of the various available distal attachment devices and a detailed technical overview of Endocuff and its modification the Endocuff Vision.
结直肠癌癌症相关死亡率可以通过筛查和早期检测来降低。任何CRC筛查计划的目的都是在早期检测尽可能多的腺瘤/息肉,因此,腺瘤检测率(ADR)是结肠镜检查的关键质量指标。多年来,人们研究和开发了各种方法和技术,以提高结肠镜检查的质量,从而增加ADR。这包括使用各种方案来改善肠道准备,为操作员确定最佳结肠镜退出时间,远端连接帽,使用不同波长的光,结肠镜检查,利用现代人工智能改善ADR。在所有各种措施中,使用远端连接装置似乎是一种简单、廉价且易于使用的技术,可以提高实时ADR。随着时间的推移,已经对各种此类装置进行了评估,从简单的透明帽、EndoRings,Endouff对Endouff Vision的有效性。在这篇综述中,我们简要介绍了各种可用的远端连接装置,并对Endouff及其改良Endouff Vision进行了详细的技术概述。
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引用次数: 0
A Simulation Study to Investigate the Usefulness of a Novel Stricture Tool for Training Wire Guided Balloon Dilation 一种用于训练丝导球囊扩张的新型结构工具的仿真研究
IF 0.7 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2022-09-01 DOI: 10.1055/s-0042-1751109
Avinash Bhat Balekuduru, M. Sahu
Background and Aims The training in esophageal stricture dilation is difficult to obtain and have few simulation models. The aim of the study was to evaluate a novel stricture simulation for training a wire-guided, controlled radial expansile (CRE) balloon dilation. Methods The study was a pretest–posttest design without a control group involving a novel simulation device for esophageal stricture. The training session involved 12 final year gastroenterology fellows from five different centers. The trainees received 2 hours of education sessions featuring didactic content, a live demonstration of step-by-step demonstration of wire-guided CRE balloon dilation and a study material on the procedure. The simulation device used was a single-use hose pipe along with a red color nonhardening modeling clay with a 5.0-to-8.0-mm hole in the center. Results All the trainees and instructor uniformly rated the model as excellent or good with simulation device being mild stiffer in haptics than of the real tissue. The mean (%) pretest scores of 39 (21.6%) improved significantly to 160 (88.8%) in mean (%) posttest questionnaire (p < 0.05). There was a significant improvement in the questionnaire of the dilation procedure after the simulation training episode. Conclusion The novel stricture simulation model had good performance evaluation and can be used to train CRE balloon dilation procedure.
背景与目的食管狭窄扩张训练难度大,模拟模型少。该研究的目的是评估一种用于训练导线引导、可控径向扩张(CRE)球囊扩张的新型结构模拟。方法采用前测后测设计,不设对照组,采用新型食管狭窄模拟装置。培训课程涉及来自5个不同中心的12名最后一年的胃肠病学研究员。受训人员接受了两小时的教育课程,内容包括教学内容、线导CRE气球逐步扩张的现场示范,以及有关过程的学习资料。所使用的模拟装置是一根一次性软管和一层红色的未硬化粘土,中间有一个5.0- 8.0 mm的孔。结果学员和指导员一致认为模型为优或良,模拟装置的触感比真实组织稍硬。后测问卷平均(%)得分由39分(21.6%)提高至160分(88.8%),差异有统计学意义(p < 0.05)。模拟训练后,扩张手术问卷有显著改善。结论该模型具有良好的性能评价,可用于CRE球囊扩张训练。
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引用次数: 3
Successful Resolution of Refractory Post-tubercular Ileocecal Stricture by Lumen Apposing Metal Stent 置管金属支架成功解决顽固性结核后回盲狭窄
IF 0.7 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2022-09-01 DOI: 10.1055/s-0042-1747961
S. Rana, Rajesh Gupta
Tuberculosis is one of the common causes of benign small bowel obstruction and endoscopic management mainly relies on serial balloon dilatation. In this report, we describe a 35 year male with refractory post-tubercular ileal stricture that was successfully treated with a lumen apposing metal stent
结核病是良性小肠梗阻的常见原因之一,内镜治疗主要依靠连续球囊扩张。在本报告中,我们描述了一名35岁的男性,患有结核后顽固性回肠狭窄,并成功地用管腔附着金属支架治疗
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引用次数: 0
Endoscopic Full Thickness Resection: A Systematic Review 内窥镜全厚度切除术的系统评价
IF 0.7 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2022-09-01 DOI: 10.1055/s-0042-1755304
P. Pal, M. Ramchandani, P. Inavolu, D. Reddy, M. Tandan
Background Endoscopic full thickness resection (EFTR) is an emerging therapeutic option for resecting subepithelial lesions (SELs) and epithelial neoplasms. We aimed to systematically review the techniques, applications, outcomes, and complications of EFTR. Methods A systematic literature search was performed using PubMed. All relevant original research articles involving EFTR were included for the review along with case report/series describing novel/rare techniques from 2001 to February 2022. Results After screening 7,739 citations, finally 141 references were included. Non-exposed EFTR has lower probability of peritoneal contamination or tumor seeding compared with exposed EFTR. Among exposed EFTR, tunneled variety is associated with lower risk of peritoneal seeding or contamination compared with non-tunneled approach. Closure techniques involve though the scope (TTS) clips, loop and clips, over the scope clips (OTSC), full thickness resection device (FTRD), and endoscopic suturing/plicating/stapling devices. The indications of EFTR range from esophagus to rectum and include SELs arising from muscularis propria (MP), non-lifting adenoma, recurrent adenoma, and even early gastric cancer (EGC) or superficial colorectal carcinoma. Other indications include difficult locations (involving appendicular orifice or diverticulum) and full thickness biopsy for motility disorders. The main limitation of FTRD is feasibility in smaller lesions (<20–25 mm), which can be circumvented by hybrid EFTR techniques. Oncologic resection with lymphadencetomy for superficial GI malignancy can be accomplished by hybrid natural orifice transluminal endoscopic surgery (NOTES) combining EFTR and NOTES. Bleeding, perforation, appendicitis, enterocolonic fistula, FTRD malfunction, peritoneal tumor seeding, and contamination are among various adverse events. Post OTSC artifacts need to be differentiated from recurrent/residual lesions to avoid re-FTRD/surgery. Conclusion EFTR is safe and effective therapeutic option for SELs, recurrent and non-lifting adenomas, tumors in difficult locations and selected cases of superficial GI carcinoma.
背景 内镜全厚度切除术(EFTR)是一种新兴的治疗选择,用于切除上皮下病变(SELs)和上皮肿瘤。我们旨在系统地回顾EFTR的技术、应用、结果和并发症。方法 使用PubMed进行系统的文献检索。2001年至2022年2月,所有涉及EFTR的相关原创研究文章以及描述新颖/罕见技术的病例报告/系列都被纳入审查。后果 筛选引用文献7739篇,最终纳入参考文献141篇。与暴露的EFTR相比,未暴露的EFTR具有更低的腹膜污染或肿瘤植入的概率。在暴露的EFTR中,与非隧道方法相比,隧道品种的腹膜播种或污染风险较低。闭合技术包括穿透镜(TTS)夹、环和夹、超镜夹(OTSC)、全厚切除装置(FTRD)和内窥镜缝合/折叠/缝合装置。EFTR的适应症范围从食道到直肠,包括固有肌层(MP)、非提升性腺瘤、复发性腺瘤,甚至早期癌症(EGC)或浅表性结直肠癌引起的SEL。其他适应症包括困难部位(涉及阑尾口或憩室)和运动障碍的全厚活检。FTRD的主要局限性是在较小病变(<20-25 mm),这可以通过混合EFTR技术来规避。浅表性胃肠道恶性肿瘤的肿瘤切除和淋巴结清扫可以通过结合EFTR和NOTES的混合自然口-腔内内镜手术(NOTES)来完成。出血、穿孔、阑尾炎、肠结肠瘘、FTRD功能障碍、腹膜肿瘤植入和污染是各种不良事件之一。需要将OTSC后伪影与复发/残留病变区分开来,以避免再次FTRD/手术。结论 EFTR是治疗SELs、复发性和非升降性腺瘤、困难部位肿瘤和浅表胃肠道癌的安全有效的选择。
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引用次数: 1
Gastrointestinal Emergencies and the Role of Endoscopy 胃肠急症和内镜检查的作用
IF 0.7 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2022-09-01 DOI: 10.1055/s-0042-1755303
V. Dixit, M. Sahu, V. Venkatesh, V. Bhargav, Vinod Kumar, Mayank Bhushan Pateriya, J. Venkataraman
Many gastrointestinal (GI) disorders present to the emergency room with acute clinical presentations, some even life threatening. Common emergencies encountered that require urgent endoscopic interventions include GI hemorrhage (variceal and nonvariceal), foreign body ingestion, obstructive jaundice, postprocedure-related complications such as postpolypectomy bleed or perforation, etc. A major advantage of emergency endoscopy is that it is cost effective and, on many occasions, can be life-saving. The present review will highlight a practical approach on various endoscopic modalities and their use in the GI emergencies.
许多胃肠道疾病以急性临床表现出现在急诊室,有些甚至危及生命。需要紧急内镜干预的常见紧急情况包括胃肠道出血(静脉曲张和非静脉曲张)、异物摄入、梗阻性黄疸、术后并发症,如息肉切除术后出血或穿孔等。紧急内镜的一个主要优点是成本效益高,在许多情况下可以挽救生命。本综述将重点介绍各种内窥镜模式的实用方法及其在胃肠道紧急情况中的应用。
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引用次数: 0
Endoscopic Self-Expanding Metallic Stent Placement in the Management of Post Laparoscopic Sleeve Gastrectomy Complications 内镜下自膨胀金属支架置入治疗腹腔镜套筒胃切除术后并发症
IF 0.7 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2022-09-01 DOI: 10.1055/s-0042-1754333
Hamidreza Goudarzi, Jacob R. Obney, Mahsa Hemmatizadeh, Taha Anbara
Introduction Endoscopic treatments have become popular by providing the best solution for healing complications while allowing oral nutrition. In this study, we aim to evaluate outcomes of the endoscopic-covered stents for staple line complications following bariatric surgery. Methods A prospective evaluation was performed for all patients treated for staple line complications after bariatric surgery. Bariatric patients with acute leaks, chronic gastrocutaneous fistulas, and anastomotic strictures refractory to endoscopic dilation after sleeve gastrectomy were included in this survey. Results From January 2019 to June 2020, 41 patients (12 with acute leaks, 16 with chronic fistulas, and 13 with strictures) were treated with endoscopic silicone-covered stents (polyester or nitinol). The mean follow-up was 3.5 months. Immediate symptomatic improvement occurred in 95.2% (91.7% of acute leaks, 81.2% of fistulas, and 92.3% of strictures). In addition, 87.8% of patients initiated oral feeding immediately after stenting. There was no mortality case in this population. Conclusion Although stent migration rarely occurs in subjects, the endoscopic silicone-covered stents strategy is one of the best treatments for anastomotic complications after bariatric surgery, providing rapid healing while simultaneously allowing for oral nutrition.
介绍 内窥镜治疗在提供口腔营养的同时,为治疗并发症提供了最佳解决方案,因此越来越受欢迎。在这项研究中,我们的目的是评估内镜下覆膜支架治疗减肥手术后吻合管并发症的效果。方法 对所有接受减肥手术后吻合钉并发症治疗的患者进行了前瞻性评估。本研究纳入了患有急性胃瘘、慢性胃皮瘘和袖状胃切除术后内镜扩张难以治疗的吻合口狭窄的减肥患者。后果 从2019年1月到2020年6月,41名患者(12名急性瘘患者,16名慢性瘘患者,13名狭窄患者)接受了内镜下硅胶覆盖支架(聚酯或镍钛诺)治疗。平均随访3.5个月。95.2%的患者立即出现症状改善(91.7%的急性渗漏,81.2%的瘘管,92.3%的狭窄)。此外,87.8%的患者在支架植入后立即开始口服喂养。该人群中没有死亡病例。结论 尽管支架移位很少发生在受试者身上,但内镜下硅胶覆盖支架策略是治疗减肥手术后吻合口并发症的最佳方法之一,可以快速愈合,同时提供口腔营养。
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引用次数: 0
Anastomotic PJ stricture: EUS-Guided PD Drainage 吻合口PJ狭窄:EUS引导的PD引流
IF 0.7 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2022-09-01 DOI: 10.1055/s-0042-1753498
Goutham Reddy Katukuri, Anudeep Katrevula, M. Ramchandani, S. Lakhtakia, N. Duvvur
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引用次数: 0
期刊
Journal of Digestive Endoscopy
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