Pub Date : 2023-03-18DOI: 10.9734/ca/2023/v12i3324
Mohamed Mahmoud El-Shawadfy, A. El-Sheikh, Sahar Abdullah El-Shedoudy, M. Ashmawy
Background: Localized or widespread non-obstructive lesions of the epicardial coronary arteries, with a luminal dilatation 1.5 times that of the neighbouring normal segments or vessel diameter, have been identified as CAE. This research was performed to determine prevalence and predictors of CAE among Delta population in Egypt. Methods: This cross-sectional research was conducted on 2850 cases over the age of 18 who came for coronary angiography with positive non-invasive diagnostic tests, acute coronary syndrome and stable CAD. Cases were divided into two groups Group I: CAE cases (n =108) and Group II Non-ectasia cases (n =2742). All cases were subjected to history taking, clinical examination, laboratory investigations, standard 12-leads ECG, resting transthoracic echocardiography (TTE) and coronary angiography. Results: CAE occurred in 108 (3.79%) of the studied cases. Total cholesterol level, serum creatinine, were insignificantly different between both groups. CRP, NLR, MPV, and PLR, were significantly higher in CAE cases versus non-Ectasia cases CRP, NLR, PLR, and MPV is a good predicator for CAE, LVESD and LVEDD, were significantly higher in CAE group. Conclusions: The RCA was the most often affected coronary artery. The existence of CAE can be predicted using easily accessible clinical laboratory values such as CRP, Neutrophil to lymphocyte ratio, mean platelet volume, and platelet to lymphocyte ratio.
{"title":"Prevalence and Predictors of Coronary Artery Ectasia among Delta Population","authors":"Mohamed Mahmoud El-Shawadfy, A. El-Sheikh, Sahar Abdullah El-Shedoudy, M. Ashmawy","doi":"10.9734/ca/2023/v12i3324","DOIUrl":"https://doi.org/10.9734/ca/2023/v12i3324","url":null,"abstract":"Background: Localized or widespread non-obstructive lesions of the epicardial coronary arteries, with a luminal dilatation 1.5 times that of the neighbouring normal segments or vessel diameter, have been identified as CAE. This research was performed to determine prevalence and predictors of CAE among Delta population in Egypt. \u0000Methods: This cross-sectional research was conducted on 2850 cases over the age of 18 who came for coronary angiography with positive non-invasive diagnostic tests, acute coronary syndrome and stable CAD. Cases were divided into two groups Group I: CAE cases (n =108) and Group II Non-ectasia cases (n =2742). All cases were subjected to history taking, clinical examination, laboratory investigations, standard 12-leads ECG, resting transthoracic echocardiography (TTE) and coronary angiography. \u0000Results: CAE occurred in 108 (3.79%) of the studied cases. Total cholesterol level, serum creatinine, were insignificantly different between both groups. CRP, NLR, MPV, and PLR, were significantly higher in CAE cases versus non-Ectasia cases CRP, NLR, PLR, and MPV is a good predicator for CAE, LVESD and LVEDD, were significantly higher in CAE group. \u0000Conclusions: The RCA was the most often affected coronary artery. The existence of CAE can be predicted using easily accessible clinical laboratory values such as CRP, Neutrophil to lymphocyte ratio, mean platelet volume, and platelet to lymphocyte ratio.","PeriodicalId":431606,"journal":{"name":"Cardiology and Angiology: An International Journal","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116786329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-11DOI: 10.9734/ca/2023/v12i3322
Junior Rocyr Ibara-Onguema, F. E. Othende, T. Camara, M. El Jamili, S. Karimi, M. Hattaoui
Aorto-right ventricular fistulas are defects of the aortic wall in the area above the right coronary cusp, where it separates aorta and right ventricular outflow tract. This entity is rare and exceptional. Often, these defects are due to trauma or infective endocarditis. We report an occasional finding of such a fistula with dramatic issue, in young patient without past medical history which admitted for rupture of cerebral mycotic aneurysm secondary to infective endocarditis with double localization (aortic and pulmonary valve).
{"title":"Aorto-right Ventricular Fistula: A Rare and Severe Complication in a Young Patient with Double Localization of Infective Endocarditis","authors":"Junior Rocyr Ibara-Onguema, F. E. Othende, T. Camara, M. El Jamili, S. Karimi, M. Hattaoui","doi":"10.9734/ca/2023/v12i3322","DOIUrl":"https://doi.org/10.9734/ca/2023/v12i3322","url":null,"abstract":"Aorto-right ventricular fistulas are defects of the aortic wall in the area above the right coronary cusp, where it separates aorta and right ventricular outflow tract. This entity is rare and exceptional. Often, these defects are due to trauma or infective endocarditis. \u0000We report an occasional finding of such a fistula with dramatic issue, in young patient without past medical history which admitted for rupture of cerebral mycotic aneurysm secondary to infective endocarditis with double localization (aortic and pulmonary valve).","PeriodicalId":431606,"journal":{"name":"Cardiology and Angiology: An International Journal","volume":"86 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125501634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-11DOI: 10.9734/ca/2023/v12i3323
H. Nabawi, Mina Boutgourine, B. Maatof, M. E. Jamili, S. Karimi, M. Hattaoui
Introduction: Infective endocarditis (IE) is a rare but potentially serious disease. It causes a high mortality and a high level of morbidity and complications. Its epidemiological, clinical and microbiological characteristics have changed in recent years. The Aim of our Work: Is to study the epidemiological, clinical, bacteriological, ultrasonographic, therapeutic and evolutionary data of IE between January 2017 and October 2022 in the Mohammed VI University Hospital and to compare them to the global profile. Materials and Methods: Retrospective study including 110 patients hospitalized for a definite IE, according to the modified DUKE criteria, in the cardiology department of the Mohammed VI University Hospital over a period of 5 years and 10 months from January 2017 to October 2022. Results: The average age of our patients was 43 years with a male predominance. The bacterial graft was on native valve in 80% with predominance of rheumatic origin (69%), on cardiac prosthesis in 10% of patients, on healthy heart (4%) and congenital heart disease (6%). The most frequent portal of entry was dental (30%). Blood cultures were positive only in 33% of patients, isolating a staphylococcus (16%), a streptococcus (14%) and a GNB (3%). Transthoracic echocardiography (TTE) showed vegetation in 108 cases, valve perforation in 7 cases, cord rupture in 1 patient and perivalvular abscess in 10 cases. Seventy-seven percent of patients had surgical treatment with a mean delay of 29 days. The overall mortality was 24% with heart failure (p<0.001), renal failure (p=0.004) and neurological complications (p=0.002) as predictive factors of mortality. Conclusion: Infective endocarditis remains a real health problem with a consequent mortality and morbidity. The population is often young, revealing the IE by complications; its prevention is the best way to improve its prognosis.
{"title":"Infective Endocarditis: Experience of the Cardiology Department of the Mohammed VI University Hospital","authors":"H. Nabawi, Mina Boutgourine, B. Maatof, M. E. Jamili, S. Karimi, M. Hattaoui","doi":"10.9734/ca/2023/v12i3323","DOIUrl":"https://doi.org/10.9734/ca/2023/v12i3323","url":null,"abstract":"Introduction: Infective endocarditis (IE) is a rare but potentially serious disease. It causes a high mortality and a high level of morbidity and complications. Its epidemiological, clinical and microbiological characteristics have changed in recent years. \u0000The Aim of our Work: Is to study the epidemiological, clinical, bacteriological, ultrasonographic, therapeutic and evolutionary data of IE between January 2017 and October 2022 in the Mohammed VI University Hospital and to compare them to the global profile. \u0000Materials and Methods: Retrospective study including 110 patients hospitalized for a definite IE, according to the modified DUKE criteria, in the cardiology department of the Mohammed VI University Hospital over a period of 5 years and 10 months from January 2017 to October 2022. \u0000Results: The average age of our patients was 43 years with a male predominance. The bacterial graft was on native valve in 80% with predominance of rheumatic origin (69%), on cardiac prosthesis in 10% of patients, on healthy heart (4%) and congenital heart disease (6%). The most frequent portal of entry was dental (30%). Blood cultures were positive only in 33% of patients, isolating a staphylococcus (16%), a streptococcus (14%) and a GNB (3%). Transthoracic echocardiography (TTE) showed vegetation in 108 cases, valve perforation in 7 cases, cord rupture in 1 patient and perivalvular abscess in 10 cases. Seventy-seven percent of patients had surgical treatment with a mean delay of 29 days. The overall mortality was 24% with heart failure (p<0.001), renal failure (p=0.004) and neurological complications (p=0.002) as predictive factors of mortality. \u0000Conclusion: Infective endocarditis remains a real health problem with a consequent mortality and morbidity. The population is often young, revealing the IE by complications; its prevention is the best way to improve its prognosis.","PeriodicalId":431606,"journal":{"name":"Cardiology and Angiology: An International Journal","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132816558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-01DOI: 10.9734/ca/2023/v12i3321
Junior Rocyr Ibara-Onguema, F. E. Othende, T. Camara, M. E. Jamili, S. Karimi, M. Hattaoui
Behcet’s disease is a systemic vasculitis of the vessels for all calibers, touching arterial and venous territories. The causes of disease are unknow. BD reaches young age subjects from 10 to 45 years and affects both men and women. BD is ubiquitous but more frequent in patients from Mediterranean basin, the middle East and Asia. The diagnosis of BD is essentially clinical. The diagnostic criteria make it possible to carry the diagnosis with good sensitivity and specifity. BD evolves by recurrent inflammatory attack. BD can affect all of the organs; cardiacs manifestations are dominated by intracardiac thrombosis, the damage of three tunics, coronaryarteritis with or without myocardial infarction, coronaries aneurysms and endomyocardial fibrosis. The vascular manifestations are dominated by arterial or venous thrombosis. The presence of dilated cardiomyopathy with reduced left ventricular ejection fraction is rare. It can be explained by ischemic or inflammatory origin by cytokines. We report a case of young woman aged of 33 years to the history of 3 episodes of bipolar aphtae which presented dilated cardiomyopathy with reduced left ventricular function, biventricular thrombosis, bilateral distal pulmonary embolism with pulmonary infarction.
{"title":"Dilated Cardiomyopathy with Biventricular Thrombi: A Severe Manifestation of Behcet Disease","authors":"Junior Rocyr Ibara-Onguema, F. E. Othende, T. Camara, M. E. Jamili, S. Karimi, M. Hattaoui","doi":"10.9734/ca/2023/v12i3321","DOIUrl":"https://doi.org/10.9734/ca/2023/v12i3321","url":null,"abstract":"Behcet’s disease is a systemic vasculitis of the vessels for all calibers, touching arterial and venous territories. The causes of disease are unknow. BD reaches young age subjects from 10 to 45 years and affects both men and women. BD is ubiquitous but more frequent in patients from Mediterranean basin, the middle East and Asia. The diagnosis of BD is essentially clinical. The diagnostic criteria make it possible to carry the diagnosis with good sensitivity and specifity. BD evolves by recurrent inflammatory attack. BD can affect all of the organs; cardiacs manifestations are dominated by intracardiac thrombosis, the damage of three tunics, coronaryarteritis with or without myocardial infarction, coronaries aneurysms and endomyocardial fibrosis. The vascular manifestations are dominated by arterial or venous thrombosis. The presence of dilated cardiomyopathy with reduced left ventricular ejection fraction is rare. It can be explained by ischemic or inflammatory origin by cytokines. We report a case of young woman aged of 33 years to the history of 3 episodes of bipolar aphtae which presented dilated cardiomyopathy with reduced left ventricular function, biventricular thrombosis, bilateral distal pulmonary embolism with pulmonary infarction.","PeriodicalId":431606,"journal":{"name":"Cardiology and Angiology: An International Journal","volume":"133 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127314386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-17DOI: 10.9734/ca/2023/v12i3320
S. Dohou, L. Codjo, K. M. Hounkponou, M. D. Soude, H. N. Amegan, C. Biaou, D. Sonou, M. P. Adjagba, M. Houenassi
Introduction: Rhythm disorders (RDs) or arrhythmias are poor prognostic factors during heart failure (HF). Our objective was to study the frequency of rhythm disorders presented by patients treated for HF in Parakou, Benin in 2017. Methods: This was a cross-sectional, descriptive and analytical study. It consisted of a systematic recruitment of all patients admitted for heart failure in the cardiology units of the city of Parakou from March to August 2017. The diagnosis of RDs was made by cardiac auscultation completed by electrocardiographic recording (standard and Holter over 24 hours). The Lown classification was used to describe the severity of ventricular TRs. The threshold for significance was p < 5%. Results: A total of 83 heart failure patients aged 61.47 ± 15.97 years with a sex ratio of 1.08 were selected. Arrhythmia was detected by auscultation in 20.48%; by standard electrocardiogram (ECG) in 25.83% and by Holter ECG in 97.59% of patients. Among the arrhythmias detected by Holter ECG, 81.48% were atrial, including 28.79% of atrial fibrillation. RDs was ventricular in 90.12% of which 47.95% were severe. Left ventricular systolic dysfunction was significantly associated with ventricular arrhythmias. On the other hand, the frequency of ventricular arrhythmias was not associated with the severity of the HF according to the NYHA classification. Conclusion: In Parakou, RDs are frequent in patients with HF. Holter ECG should be included in the follow-up of heart failure patients in order to improve their management.
{"title":"Screenning of Arrhythmias in Patients Treated for Heart Failure in Parakou in 2017","authors":"S. Dohou, L. Codjo, K. M. Hounkponou, M. D. Soude, H. N. Amegan, C. Biaou, D. Sonou, M. P. Adjagba, M. Houenassi","doi":"10.9734/ca/2023/v12i3320","DOIUrl":"https://doi.org/10.9734/ca/2023/v12i3320","url":null,"abstract":"Introduction: Rhythm disorders (RDs) or arrhythmias are poor prognostic factors during heart failure (HF). Our objective was to study the frequency of rhythm disorders presented by patients treated for HF in Parakou, Benin in 2017. \u0000Methods: This was a cross-sectional, descriptive and analytical study. It consisted of a systematic recruitment of all patients admitted for heart failure in the cardiology units of the city of Parakou from March to August 2017. The diagnosis of RDs was made by cardiac auscultation completed by electrocardiographic recording (standard and Holter over 24 hours). The Lown classification was used to describe the severity of ventricular TRs. The threshold for significance was p < 5%. \u0000Results: A total of 83 heart failure patients aged 61.47 ± 15.97 years with a sex ratio of 1.08 were selected. Arrhythmia was detected by auscultation in 20.48%; by standard electrocardiogram (ECG) in 25.83% and by Holter ECG in 97.59% of patients. Among the arrhythmias detected by Holter ECG, 81.48% were atrial, including 28.79% of atrial fibrillation. RDs was ventricular in 90.12% of which 47.95% were severe. Left ventricular systolic dysfunction was significantly associated with ventricular arrhythmias. On the other hand, the frequency of ventricular arrhythmias was not associated with the severity of the HF according to the NYHA classification. \u0000Conclusion: In Parakou, RDs are frequent in patients with HF. Holter ECG should be included in the follow-up of heart failure patients in order to improve their management.","PeriodicalId":431606,"journal":{"name":"Cardiology and Angiology: An International Journal","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126832927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-16DOI: 10.9734/ca/2023/v12i3319
A. Tahir, M. Njie, P. M. Mulendelé, M. Foudail, M. Haboub, S. Arous, M. Benouna, A. Drighil, L. Azzouzi, R. Habbal
LVNC (left ventricular non-compaction) is a rare congenital cardiomyopathy with a reported incidence of 0.05% in adults. It can occur in isolation or affect both ventricles. It’s characterized by prominent LV trabeculae and deep intertrabecular recesses which are filled with blood from the ventricular cavity without evidence of communication to the epicardial coronary artery system. Frequent premature supra ventricular tachycardia as unique finding in LVNC cardiomyopathy is rare manifestation of this disease. We report a case of a frequent persistent supraventricular tachycardia as first manifestation of a patient with LVNC cardiomyopathy in a young healthy woman who despite radio frequency ablation therapy of the supraventricular tachycardia remains symptomatic. The patient was later placed on medical therapy based on a non-cardio selective beta-blocker with a good clinical outcome without recurrent of supra-ventricular arrythmias.
{"title":"A Young Healthy Woman with Supraventricular Tachycardia Reveals an Underlying Left Ventricular Non-compaction Cardiomyopathy: A Rare Case Report","authors":"A. Tahir, M. Njie, P. M. Mulendelé, M. Foudail, M. Haboub, S. Arous, M. Benouna, A. Drighil, L. Azzouzi, R. Habbal","doi":"10.9734/ca/2023/v12i3319","DOIUrl":"https://doi.org/10.9734/ca/2023/v12i3319","url":null,"abstract":"LVNC (left ventricular non-compaction) is a rare congenital cardiomyopathy with a reported incidence of 0.05% in adults. It can occur in isolation or affect both ventricles. It’s characterized by prominent LV trabeculae and deep intertrabecular recesses which are filled with blood from the ventricular cavity without evidence of communication to the epicardial coronary artery system. Frequent premature supra ventricular tachycardia as unique finding in LVNC cardiomyopathy is rare manifestation of this disease. We report a case of a frequent persistent supraventricular tachycardia as first manifestation of a patient with LVNC cardiomyopathy in a young healthy woman who despite radio frequency ablation therapy of the supraventricular tachycardia remains symptomatic. The patient was later placed on medical therapy based on a non-cardio selective beta-blocker with a good clinical outcome without recurrent of supra-ventricular arrythmias.","PeriodicalId":431606,"journal":{"name":"Cardiology and Angiology: An International Journal","volume":"262 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121713554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-11DOI: 10.9734/ca/2023/v12i3318
Alaa Eddin Talaat Abd Alkarim, Amany Mohamed Allaithy, Hatem Mohamed El Sokkary, Mohamed Setiha
Background: The cardiac changes associated with diabetes are thought to comprise thickening of the myocardium and is characterized by predominantly diastolic dysfunction (DD), the diabetic cardiomyopathy. So, this study aimed to evaluate cardiac impairments in patients in delta region with type 2 diabetes mellitus using resting electrocardiogram (ECG) and resting transthoracic echocardiography. Methods: This was a cross-sectional study carried out on 50 diabetic patients to evaluate of cardiac impairments in patients in delta region with type 2 diabetes mellitus using resting ECG and resting transthoracic echocardiography at the Department of Cardiology, Tanta University Hospitals in a period of six months starting from January 2020 till June 2020. Results: There were significant negative correlations between abnormal echocardiography with (body mass index) BMI, duration of diabetes and systolic blood pressure (SBP) (P<0.05). The sensitivity of ejection fraction (EF), early trans-mitral flow velocity (E), atrial trans-mitral flow velocity (A) and E/A in detecting cardiac changes in type 2 diabetes mellitus (DM) was 68%, 52%, 76%, 72% and specificity was 52%, 68%, 36%, 30% at cut-off value 65, 75, 65, 77.5 and AUC 0.619, 0.606, 0.538, 0.534, respectively (P> 0.05). Conclusions: The effect of DM on the left ventricular (LV) diastolic function is still controversial. Therefore, they need to be further substantiated, preferably with evidence from extensive longitudinal studies in people with type 2 diabetes representative of type 2 diabetes healthcare populations. Echocardiographic and ECG abnormalities are very common in outpatients with type 2 diabetes. DD is the main cardiac impairment caused by DM.
{"title":"Role of Resting Electrocardiography and Transthoracic Echocardiography in the Diagnosis of Cardiac Impairments in Type 2 Diabetics","authors":"Alaa Eddin Talaat Abd Alkarim, Amany Mohamed Allaithy, Hatem Mohamed El Sokkary, Mohamed Setiha","doi":"10.9734/ca/2023/v12i3318","DOIUrl":"https://doi.org/10.9734/ca/2023/v12i3318","url":null,"abstract":"Background: The cardiac changes associated with diabetes are thought to comprise thickening of the myocardium and is characterized by predominantly diastolic dysfunction (DD), the diabetic cardiomyopathy. So, this study aimed to evaluate cardiac impairments in patients in delta region with type 2 diabetes mellitus using resting electrocardiogram (ECG) and resting transthoracic echocardiography. \u0000Methods: This was a cross-sectional study carried out on 50 diabetic patients to evaluate of cardiac impairments in patients in delta region with type 2 diabetes mellitus using resting ECG and resting transthoracic echocardiography at the Department of Cardiology, Tanta University Hospitals in a period of six months starting from January 2020 till June 2020. \u0000Results: There were significant negative correlations between abnormal echocardiography with (body mass index) BMI, duration of diabetes and systolic blood pressure (SBP) (P<0.05). The sensitivity of ejection fraction (EF), early trans-mitral flow velocity (E), atrial trans-mitral flow velocity (A) and E/A in detecting cardiac changes in type 2 diabetes mellitus (DM) was 68%, 52%, 76%, 72% and specificity was 52%, 68%, 36%, 30% at cut-off value 65, 75, 65, 77.5 and AUC 0.619, 0.606, 0.538, 0.534, respectively (P> 0.05). \u0000Conclusions: The effect of DM on the left ventricular (LV) diastolic function is still controversial. Therefore, they need to be further substantiated, preferably with evidence from extensive longitudinal studies in people with type 2 diabetes representative of type 2 diabetes healthcare populations. Echocardiographic and ECG abnormalities are very common in outpatients with type 2 diabetes. DD is the main cardiac impairment caused by DM.","PeriodicalId":431606,"journal":{"name":"Cardiology and Angiology: An International Journal","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128239503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-11DOI: 10.9734/ca/2023/v12i3317
Nabil Mohammed Elshabrawy, Amany Mohamed Allaithy, M. Elsaidy, Magdy Mohamed Al Masry
Background: Hypertension is considered as the silent killer of human because the hypertensive patient may be not aware that he has hypertension and death can occur at any time without the reason being known. We aim to study the effect of gray zone hypertension [SBP from 120-139] and or [DBP from 80-89] which was classified as prehypertension under JNC-7 on the structure, geometry, and operation of the left ventricle using echocardiography Methods: This study included 100 patients who asymptomatic apparent healthy subjects visited cardiology outpatient department (OPD) for routine checkup. Patients were grouped into two equal groups: Group A whose blood pressure was in the gray zone hypertension [SBP from 120-139] and or [DBP from 80-89], and group B with SBP <120 mmHg & DBP <80 mmHg. Results: The two groups being studied were statistically significant different as regard LV geometrical pattern (p=0.028). They were also statistically significant in LV geometrical pattern between the males and females (p<0.05). The two groups were statistically significant different regarding GLS (p =0.001). Conclusions: Gray zone hypertension affects ventricular diastolic function and LV geometry, although systolic function was normal; GLS showed that subclinical LV dysfunction can occur.
{"title":"Left Ventricular Geometry and Function in Patients with Gray Zone Hypertension","authors":"Nabil Mohammed Elshabrawy, Amany Mohamed Allaithy, M. Elsaidy, Magdy Mohamed Al Masry","doi":"10.9734/ca/2023/v12i3317","DOIUrl":"https://doi.org/10.9734/ca/2023/v12i3317","url":null,"abstract":"Background: Hypertension is considered as the silent killer of human because the hypertensive patient may be not aware that he has hypertension and death can occur at any time without the reason being known. We aim to study the effect of gray zone hypertension [SBP from 120-139] and or [DBP from 80-89] which was classified as prehypertension under JNC-7 on the structure, geometry, and operation of the left ventricle using echocardiography \u0000Methods: This study included 100 patients who asymptomatic apparent healthy subjects visited cardiology outpatient department (OPD) for routine checkup. Patients were grouped into two equal groups: Group A whose blood pressure was in the gray zone hypertension [SBP from 120-139] and or [DBP from 80-89], and group B with SBP <120 mmHg & DBP <80 mmHg. \u0000Results: The two groups being studied were statistically significant different as regard LV geometrical pattern (p=0.028). They were also statistically significant in LV geometrical pattern between the males and females (p<0.05). The two groups were statistically significant different regarding GLS (p =0.001). \u0000Conclusions: Gray zone hypertension affects ventricular diastolic function and LV geometry, although systolic function was normal; GLS showed that subclinical LV dysfunction can occur.","PeriodicalId":431606,"journal":{"name":"Cardiology and Angiology: An International Journal","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133527853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-09DOI: 10.9734/ca/2023/v12i2315
Ahmed Mahmoud El Amrawy, Mahmoud Hassan Abdelnabi, Abdallah Almaghraby
Background: Revascularization of the coronary arteries is associated with better short term and long term prognosis in patients having multivessel coronary artery disease (MV-CAD) and chronic kidney disease (CKD). However, whether revascularization using coronary artery bypass grafting (CABG) surgery or percutaneous coronary intervention (PCI) using drug eluting stents (DES) is better remains unknown.
Objectives: To compare the outcomes of revascularization by multi-vessel PCI using DES versus revascularization by CABG in patients with CKD having multivessel CAD, regarding in-hospital and one-year major adverse cardiovascular and cerebrovascular events (MACCE).
Methods: This was a retrospective analysis of the data of a group of patients having CKD with eGFR less than 60 ml/min with multivessel CAD who underwent revascularization by PCI or revascularization by CABG and were compared as regards in-hospital and one-year MAACE.
Results: A total of 565 patients were reviewed in this study, 230 patients had multivessel PCI using DES while 335 patients had CABG. Comparing both revascularization groups regarding in-hospital MACCE, patients who had mutli-vessel PCI had significantly lower in-hospital mortality, cerebrovascular events (stroke/TIA) and lower total MACCE than patients who had CABG (P-value = 0.03 & 0.01 & 0.04 respectively). When comparing both revascularization groups regarding one-year MACCE, patients who had mutli-vessel PCI had significantly lower cerebrovascular events and total MACCE than those patients who had CABG (P-value = 0.02 & 0.03 respectively).
Conclusion: This is a retrospective study to determine which strategy is better for revascularization of CKD patients having multivessel CAD; we can conclude that multi-vessel PCI using DES for CKD patients and multivessel CAD had advantages over CABG regarding in-hospital and one-year cerebrovascular accidents (TIA/stroke) and regarding total MACCE. Larger randomized controlled trials are required to confirm our findings.
{"title":"Multi-vessel Disease Percutaneous Coronary Intervention versus Coronary Artery Bypass Grafting in Patients with Chronic Kidney Disease","authors":"Ahmed Mahmoud El Amrawy, Mahmoud Hassan Abdelnabi, Abdallah Almaghraby","doi":"10.9734/ca/2023/v12i2315","DOIUrl":"https://doi.org/10.9734/ca/2023/v12i2315","url":null,"abstract":"Background: Revascularization of the coronary arteries is associated with better short term and long term prognosis in patients having multivessel coronary artery disease (MV-CAD) and chronic kidney disease (CKD). However, whether revascularization using coronary artery bypass grafting (CABG) surgery or percutaneous coronary intervention (PCI) using drug eluting stents (DES) is better remains unknown.
 Objectives: To compare the outcomes of revascularization by multi-vessel PCI using DES versus revascularization by CABG in patients with CKD having multivessel CAD, regarding in-hospital and one-year major adverse cardiovascular and cerebrovascular events (MACCE).
 Methods: This was a retrospective analysis of the data of a group of patients having CKD with eGFR less than 60 ml/min with multivessel CAD who underwent revascularization by PCI or revascularization by CABG and were compared as regards in-hospital and one-year MAACE.
 Results: A total of 565 patients were reviewed in this study, 230 patients had multivessel PCI using DES while 335 patients had CABG. Comparing both revascularization groups regarding in-hospital MACCE, patients who had mutli-vessel PCI had significantly lower in-hospital mortality, cerebrovascular events (stroke/TIA) and lower total MACCE than patients who had CABG (P-value = 0.03 & 0.01 & 0.04 respectively). When comparing both revascularization groups regarding one-year MACCE, patients who had mutli-vessel PCI had significantly lower cerebrovascular events and total MACCE than those patients who had CABG (P-value = 0.02 & 0.03 respectively).
 Conclusion: This is a retrospective study to determine which strategy is better for revascularization of CKD patients having multivessel CAD; we can conclude that multi-vessel PCI using DES for CKD patients and multivessel CAD had advantages over CABG regarding in-hospital and one-year cerebrovascular accidents (TIA/stroke) and regarding total MACCE. Larger randomized controlled trials are required to confirm our findings.","PeriodicalId":431606,"journal":{"name":"Cardiology and Angiology: An International Journal","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136171128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-09DOI: 10.9734/ca/2023/v12i2316
Mohammed El-Refaey El-Mashad, M. El-Masry, Suzan Bayoumy Al-Hefnawy, A. Elsheikh
Background: Cirrhosis is a long-term inflammatory process of hepatic tissue condition that mainly affects people aged 50 to 60. This study aims to assess Left ventricular diastolic dysfunction (LVDD) in cases with cirrhotic liver by conventional, tissue Doppler and two-dimensional speckle tracking echocardiography to clarify the correlation between the severity of cirrhotic liver and LVDD. Methods: A prospective case-control research involved 100 adult cases with confirmed HCV and HBV. Cases were divided into 4 equal group: Group A: Child A cases, group B: Child B cases, group C: Child C cases and group D (Controls): healthy non-hepatic subjects of the same age and sex who have normal blood pressure, nonsmoking participants with no further concomitant problems. Results: Number of cases with LVDD had a statistical noticeable increase in Child A, B, and C (p =0.004, <0.001, and <0.001 respectively. LAVi had a statistical noticeable increase in Child C / B (p =0.013 and p =0.014). Conclusion: Left atrial volume index (LAVi) had a statistical noticeable increase in Child C / B in comparison to the controls but E m, E l were statistical noticeable lower in Child C / B. /E had a statistical noticeable increase in Child C group, LVSRe had a statistical noticeable decrease in Child C group but it was insignificantly different across Child A / B/ C and controls and across Child B / C and controls.
背景:肝硬化是一种肝脏组织的长期炎症过程，主要影响50 - 60岁人群。本研究旨在通过常规超声心动图、组织多普勒超声心动图和二维散斑跟踪超声心动图评估肝硬化患者左室舒张功能障碍(LVDD)，以明确肝硬化严重程度与LVDD的相关性。方法:前瞻性病例对照研究纳入100例成人确诊HCV和HBV病例。病例分为4个相等组:A组:儿童A例，B组:儿童B例，C组:儿童C例，D组(对照组):年龄和性别相同，血压正常，不吸烟，无其他并发症的健康非肝脏受试者。结果:患儿a、B、C组LVDD例数有统计学意义的显著增加(p =0.004， <0.001， <0.001)。LAVi患儿C / B增高有统计学意义(p =0.013和p =0.014)。结论:Child C / B组左房容积指数(LAVi)较对照组有统计学意义升高，Child C / B组E m、E l较对照组有统计学意义降低，Child C组左房容积指数(LAVi)较对照组有统计学意义升高，Child C组左房容积指数(LVSRe)较对照组有统计学意义降低，但Child a / B/ C组与对照组、Child B/ C组与对照组差异无统计学意义。
{"title":"Assessment of Left Ventricular Diastolic Dysfunction in Cases with Liver Cirrhosis","authors":"Mohammed El-Refaey El-Mashad, M. El-Masry, Suzan Bayoumy Al-Hefnawy, A. Elsheikh","doi":"10.9734/ca/2023/v12i2316","DOIUrl":"https://doi.org/10.9734/ca/2023/v12i2316","url":null,"abstract":"Background: Cirrhosis is a long-term inflammatory process of hepatic tissue condition that mainly affects people aged 50 to 60. This study aims to assess Left ventricular diastolic dysfunction (LVDD) in cases with cirrhotic liver by conventional, tissue Doppler and two-dimensional speckle tracking echocardiography to clarify the correlation between the severity of cirrhotic liver and LVDD. \u0000Methods: A prospective case-control research involved 100 adult cases with confirmed HCV and HBV. Cases were divided into 4 equal group: Group A: Child A cases, group B: Child B cases, group C: Child C cases and group D (Controls): healthy non-hepatic subjects of the same age and sex who have normal blood pressure, nonsmoking participants with no further concomitant problems. \u0000Results: Number of cases with LVDD had a statistical noticeable increase in Child A, B, and C (p =0.004, <0.001, and <0.001 respectively. LAVi had a statistical noticeable increase in Child C / B (p =0.013 and p =0.014). \u0000Conclusion: Left atrial volume index (LAVi) had a statistical noticeable increase in Child C / B in comparison to the controls but E m, E l were statistical noticeable lower in Child C / B. /E had a statistical noticeable increase in Child C group, LVSRe had a statistical noticeable decrease in Child C group but it was insignificantly different across Child A / B/ C and controls and across Child B / C and controls.","PeriodicalId":431606,"journal":{"name":"Cardiology and Angiology: An International Journal","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117219213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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