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An Interesting Case of Penetrating Brain Injury Due to Assault with Meat Chopper Knife 一个有趣的切肉刀袭击致穿透性脑损伤案例
IF 0.2 Pub Date : 2024-01-22 DOI: 10.1055/s-0044-1778733
Bal Krishna Ojha, Qazi Zeeshan, Rahul Miglani
Penetrating injuries to brain are rare and mostly result from warfare injuries, suicidal/homicidal firearm injuries, or accidental injuries. In general, they are associated with poor outcome. We report the challenges faced in managing an interesting case of penetrating brain injury as a result of assault with meat chopper knife that underwent surgical intervention and had a good outcome.
穿透性脑损伤很少见,大多由战争伤害、自杀/凶器伤害或意外伤害造成。一般来说,这类损伤的预后较差。我们报告了在处理一例有趣的切肉刀袭击导致的穿透性脑损伤病例时所面临的挑战,该病例接受了手术干预,结果良好。
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引用次数: 0
Ethical Issues in Neurotrauma: Challenges and Solutions 神经创伤中的伦理问题:挑战与解决方案
IF 0.2 Pub Date : 2023-07-20 DOI: 10.1055/s-0043-1771227
Ahtesham Khizar, Abdul Ghafoor, Inaam Elahi
Abstract Neurotrauma is a medical field that deals with the treatment and prevention of serious injuries to the brain, spinal cord, or peripheral nerves. It presents complex ethical issues that require careful consideration and balance between individual autonomy, public health, patient preferences, and clinical outcomes. In this review, we examine several ethical dilemmas in neurotrauma, including the prevention of traumatic events, obtaining informed consent and respecting patient preferences in situations of impaired cognition and communication, determining the appropriate use of life-saving interventions, and communicating with patients and families about prognosis and outcomes. Our analysis highlights the need for a nuanced and evidence-based approach that takes into account the unique circumstances of each patient and balances the potential benefits and risks of various interventions.
神经创伤是一个医学领域,涉及脑、脊髓或周围神经严重损伤的治疗和预防。它提出了复杂的伦理问题,需要仔细考虑和平衡个人自主权、公共卫生、患者偏好和临床结果。在这篇综述中,我们研究了神经创伤中的几个伦理困境,包括创伤事件的预防,在认知和沟通受损的情况下获得知情同意和尊重患者的偏好,确定适当使用挽救生命的干预措施,以及与患者和家属沟通预后和结果。我们的分析强调需要一种细致入微的循证方法,考虑到每个患者的独特情况,平衡各种干预措施的潜在益处和风险。
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引用次数: 0
Skin Temperature Measurement in Acute Neurotrauma: The Unknown Tool 皮肤温度测量在急性神经损伤:未知的工具
IF 0.2 Pub Date : 2023-07-13 DOI: 10.1055/s-0043-1769800
Tariq Janjua, L. Moscote-Salazar
Human body temperature has physiological and deleterious implications. The re fl ection of temperature is from dysfunction at the metabolic level to dysfunction of organs. Body temperature is one of the key vital signs for homeostasis. The brain is one of the key locations where temperature fl uctuation can lead to a major clinical impact on the body. As a matter of fact, the brain controls body temperature through the central controller in the hypothalamus. The brain is susceptible to injury even with small systemic changes in temperature. The development of fever due to systemic causes has been considered a factor associated with the core approach for critically ill patients
人体温度具有生理和有害的影响。温度的反映是从代谢水平的功能障碍到器官的功能障碍。体温是维持体内平衡的重要指标之一。大脑是温度波动会对身体产生重大临床影响的关键部位之一。事实上,大脑通过位于下丘脑的中央控制器来控制体温。即使是全身温度的微小变化,大脑也容易受到伤害。由于全身性原因引起的发热被认为是与危重病人的核心方法相关的一个因素
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引用次数: 0
Neurotrauma Care: A Pakistani Perspective 神经创伤护理:巴基斯坦视角
IF 0.2 Pub Date : 2023-07-13 DOI: 10.1055/s-0043-1769803
Ahtesham Khizar
Dear editor, Neurotrauma is a medical condition that occurs due to an injury to the brain or spinal cord. In Pakistan, neurotrauma care is a significant concern due to a high incidence of traumatic brain injury (TBI) resulting from road traffic accidents, falls, and violence.1 According to a recent study, Pakistan had 81 TBI cases per 100,000 population, with a 15% fatality rate.2 TBI is a leading cause of mortality and morbidity in the country, with an estimated 600,000 cases reported each year. However, despite the high incidence of TBI, neurotrauma care in Pakistan remains inadequate, and there is a need to improve the quality and accessibility of services. In Pakistan, the management of neurotrauma is challenging due to a lack of infrastructure, trained personnel, and resources. Most of the patients with neurotrauma are referred to tertiary care centers for specialized treatment, but these centers are limited in number and are mainly located in major cities. The lack of adequate transport systems and long distances to these centers result in delayed treatment, which often exacerbates the patient’s condition and increases the risk of mortality. The availability of trained personnel is another significant challenge in neurotrauma care. In Pakistan, there is a shortage of neurosurgeons, and those available are concentrated in urban centers. This concentration of specialists makes it challenging for patients in remote and rural areas to access specialized care. Additionally, the lack of trained personnel in emergency departments and critical care units further limits the quality of care provided to patients with neurotrauma. The resources available for neurotrauma care in Pakistan are also limited. There is a shortage of essential medical equipment, such as ventilators, monitors, and imaging equipment, which are critical for the diagnosis and treatment of neurotrauma patients. This lack of equipment is particularly acute in rural areas, where even basic medical supplies are scarce. The shortage of resources further limits the ability of medical professionals to provide quality care to patients with neurotrauma. Another significant challenge in neurotrauma care in Pakistan is the lack of public awareness and education.3 Due to the lack of awareness, many patients do not seek medical attention immediately after sustaining an injury. This delay in seeking treatment often exacerbates the patient’s condition, leading to higher mortality and morbidity rates. Additionally, the lack of education among the general public regarding the management and prevention of neurotrauma increases the incidence of these injuries. Despite these challenges, efforts are being made to improve neurotrauma care in Pakistan. One such initiative is the establishment of neurotrauma centers across the country. These centers provide specialized care to patients with neurotrauma and help to bridge the gap between urban and rural areas. The centers are equipped with specialized me
亲爱的编辑,神经创伤是一种因大脑或脊髓受伤而发生的医学疾病。在巴基斯坦,由于道路交通事故、跌倒和暴力导致的创伤性脑损伤(TBI)发生率很高,神经创伤护理是一个值得关注的问题根据最近的一项研究,巴基斯坦每10万人中有81例脑外伤病例,死亡率为15%外伤性脑损伤是该国死亡和发病的主要原因,估计每年报告60万例。然而,尽管外伤性脑损伤的发病率很高,巴基斯坦的神经创伤护理仍然不足,需要提高服务的质量和可及性。在巴基斯坦,由于缺乏基础设施、训练有素的人员和资源,神经创伤的管理具有挑战性。大多数神经创伤患者被转诊到三级保健中心进行专门治疗,但这些中心数量有限,而且主要位于大城市。由于缺乏足够的运输系统和到这些中心的距离很远,导致治疗延误,这往往使患者的病情恶化,并增加死亡的风险。训练有素的人员的可用性是神经创伤护理的另一个重大挑战。在巴基斯坦,神经外科医生短缺,而这些人都集中在城市中心。专家的集中使得偏远和农村地区的患者难以获得专业护理。此外,急诊科和重症监护病房缺乏训练有素的人员,进一步限制了向神经创伤患者提供的护理质量。巴基斯坦可用于神经创伤护理的资源也很有限。缺少必要的医疗设备,如呼吸机、监测器和成像设备,这些设备对神经创伤患者的诊断和治疗至关重要。这种缺乏设备的情况在农村地区尤为严重,那里连基本的医疗用品都稀缺。资源短缺进一步限制了医疗专业人员向神经创伤患者提供高质量护理的能力。巴基斯坦神经创伤护理的另一个重大挑战是缺乏公众意识和教育由于缺乏意识,许多患者在受伤后没有立即就医。这种寻求治疗的延迟往往使患者的病情恶化,导致更高的死亡率和发病率。此外,缺乏教育的一般公众关于管理和预防神经创伤增加了这些伤害的发生率。尽管存在这些挑战,巴基斯坦仍在努力改善神经创伤护理。其中一项倡议是在全国范围内建立神经创伤中心。这些中心为神经创伤患者提供专门护理,并帮助弥合城市和农村地区之间的差距。这些中心配备了专门的医疗设备,并配备了训练有素的人员,包括神经外科医生、重症监护医生和急诊医学专家。此外,还启动了针对医疗专业人员的培训计划,以提高他们在神经创伤管理方面的知识和技能。这些培训项目涵盖了创伤性脑损伤的诊断和管理、重症监护管理和神经外科手术等主题。其目的是为医疗专业人员提供必要的知识和技能,以有效地管理神经创伤患者。还开展了提高公众意识的运动,以提高公众对预防和管理神经创伤的认识。这些活动的重点是教育公众
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引用次数: 0
Dilemmas in the Management of Acute TBI: A Prospective Observational Study of Anterior Pituitary Dysfunction and Its Correlation with Outcome 急性TBI治疗的困境:前叶垂体功能障碍的前瞻性观察研究及其与预后的相关性
IF 0.2 Pub Date : 2023-07-13 DOI: 10.1055/s-0043-1769802
A. Choudhary, S. Sobti, N. Dev, B. Kulshreshtha, R. Sharma, K. Kaushik, Ashok Kumar
Abstract Background  The frequency and pattern of endocrinal abnormalities among patients with traumatic brain injury occur more frequently than previously suspected. Objective  The aim of this study was to assess anterior pituitary dysfunction in patients with moderate-to-severe traumatic brain injury and outcome after treatment. Material and Methods  One hundred patients with moderate-to-severe head injury presenting within 48 hours of injury were enrolled. Blood samples of all patients were taken for the hormonal assay at second day, at 2 weeks, 1 month, 3 months, and 6 months. Patients were evaluated by Glasgow coma scale (GCS), Glasgow outcome score (GOS), and hormone profile. Results  The median GCS score was 10/15. Forty-four patients were operated and 56 patients were managed medically. Seven operated patients expired; 30 patients had good recovery. In conservative group, 46 patients had good outcome and two patients died. Cortisol and thyroid hormone values were changed prominently, followed by prolactin and growth hormone. On univariate analysis, association of GOS with fT3, fT4, serum prolactin, and serum cortisol was seen. On multivariate analysis, strong correlation of GOS with f T4 values was seen ( p  = 0.008) Conclusion  Most of the hormonal deficiency occurs in immediate phase. Hormonal screening should be done to improve long term outcome.
背景外伤性脑损伤患者内分泌异常的发生频率和模式比以往所认为的更为频繁。目的探讨中重度颅脑外伤患者的垂体前叶功能障碍及其治疗效果。材料与方法选取100例在48小时内出现的中重度颅脑损伤患者。所有患者于第2天、第2周、第1个月、第3个月和第6个月采血进行激素测定。通过格拉斯哥昏迷评分(GCS)、格拉斯哥结局评分(GOS)和激素谱对患者进行评估。结果GCS评分中位数为10/15。手术治疗44例,内科治疗56例。手术结束7例;30例患者恢复良好。保守组46例预后良好,2例死亡。皮质醇和甲状腺激素变化显著,其次是催乳素和生长激素。单因素分析显示,GOS与fT3、fT4、血清催乳素和血清皮质醇相关。多因素分析显示GOS与ft4值相关性较强(p = 0.008)。结论激素缺乏多发生在急性期。应进行激素筛查以改善长期预后。
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引用次数: 0
When a Transorbital Penetrating Brain Injury Reveals the Infratentorial Tumor: A Case Report and Technical Note 经眼眶穿透性脑损伤显示幕下肿瘤:1例报告及技术笔记
IF 0.2 Pub Date : 2023-07-13 DOI: 10.1055/s-0043-1769801
Charles Champeaux-Depond, T. Passeri, Y. Caudron
Abstract A 62-year-old man was referred for a transorbital injury. A preoperative computed tomography scanner confirmed an 8 cm long × 14 mm wooden piece penetrating the right orbit and perforating the anterior cranial base until the frontal lobe with no apparent prominent vascular injury. However, an unexpected posterior fossa tumor causing blocked hydrocephalus was unveiled. Extraction of the wooden stick was safely achieved after intracranial exploration followed by meticulous cleaning and careful watertight closure to prevent cerebrospinal fluid (CSF) leakage. Except the right eyesight loss, he initially recovered well, were it not for his hard-to-treat hydrocephalus. What at the time of its discovery seemed to be a less important but very likely the indirect cause of its injury, became unexpectedly problematic. Despite all CSF diversion procedures, the patient worsened gradually. Neither a failed attempt to remove the tumor due to the fourth ventricle floor broad infiltration nor the posterior fossa decompressive craniectomy succeeded in improving his neurological status. Despite the diagnosis of a grade II ependymoma, the tumor demonstrated an aggressive radiological behavior with an intense edema of the brainstem, possibly the cause of his drowsiness. Unfortunately, he died of tumor progression solely 52 days after his transorbital injury.
摘要一位62岁男性因眼眶外伤被转诊。术前计算机断层扫描证实一根长8厘米× 14毫米的木片穿透右眼眶,穿过前颅底直至额叶,未见明显的血管损伤。然而,一个意想不到的后窝肿瘤导致闭塞脑积水被揭露。在颅内探查后,仔细清洁并仔细密封,以防止脑脊液(CSF)泄漏,安全取出木棒。除了右眼视力下降外,他最初恢复得很好,如果不是因为难以治疗的脑积水的话。在发现它的时候,它似乎是一个不太重要的,但很可能是它受伤的间接原因,意想不到地变成了问题。尽管进行了所有脑脊液转移手术,患者病情仍逐渐恶化。由于第四脑室底广泛浸润而未能成功切除肿瘤,后颅窝减压切除术也未能成功改善患者的神经系统状况。尽管诊断为II级室管膜瘤,但肿瘤表现出侵袭性的放射表现,脑干剧烈水肿,可能是他嗜睡的原因。不幸的是,他在眼眶受伤后52天就死于肿瘤进展。
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引用次数: 0
Traumatic Acute Vertex Epidural Hematoma(vEDH): A Case Report 外伤性急性顶点硬膜外血肿1例
IF 0.2 Pub Date : 2023-07-13 DOI: 10.1055/s-0043-1769799
L. Tyngkan, Memida Laloo, Mebanshanbor Garod Pasi
Abstract Vertex epidural hematoma (vEDH) is a rare type of intracranial hematoma, which accounts for 0.024% of all head injuries and 0.47 to 8.2% of intracranial hematoma, with high mortality rate of approximately 50% if not detected early. We report a case of 30-year-old male with fall from height presenting with headache and bradycardia. Craniotomy with complete evacuation of vEDH was done. vEDH is a relatively rare entity and in suspected case of vEDH one should always get thin cuts of computed tomography along with sagittal and coronal cuts.
顶点硬膜外血肿(vEDH)是一种罕见的颅内血肿类型,占所有颅脑损伤的0.024%,颅内血肿的0.47 ~ 8.2%,如不及早发现,死亡率高达50%左右。我们报告一例30岁男性从高处坠落,表现为头痛和心动过缓。开颅,vEDH完全排出。vEDH是一种相对罕见的实体,在疑似vEDH的病例中,应经常进行计算机断层扫描,同时进行矢状面和冠状面切面。
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引用次数: 0
Chronic Subdural Hematoma: Past, Present, and Future 慢性硬膜下血肿:过去、现在和未来
IF 0.2 Pub Date : 2023-07-10 DOI: 10.1055/s-0043-1771000
Pragnesh Bhatt
Chronic subdural hematoma (CSDH) is a common neurosurgical condition characterized by abnormal collection of blood products in the subdural space with indolent course of progression. Its pathophysiology is complex and many theories have been put forward over time. Its presentation varies from a minimally symptomatic event to potentially serious neurosurgical emergencies. The surgical evacuation is the mainstay of its management although there has been some interest in pharmacological and minimally invasive endovascular options in this millennium. The prognosis depends on a number of factors, some of which are interdependent.
慢性硬膜下血肿(CSDH)是一种常见的神经外科疾病,其特点是血制品在硬膜下间隙异常聚集,进展缓慢。其病理生理学十分复杂,长期以来提出了许多理论。其表现形式多种多样,有的症状轻微,有的则可能是严重的神经外科急症。手术切除是其主要的治疗方法,尽管本世纪以来人们对药物治疗和微创血管内治疗产生了一些兴趣。预后取决于多种因素,其中有些因素是相互依存的。
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引用次数: 0
Automated Detection of Intracranial Hemorrhage from Head CT Scans Applying Deep Learning Techniques in Traumatic Brain Injuries: A Comparative Review 应用深度学习技术在创伤性脑损伤中的颅脑CT扫描颅内出血自动检测:比较综述
IF 0.2 Pub Date : 2023-07-10 DOI: 10.1055/s-0043-1770770
D. Agrawal, Latha Poonamallee, Sharwari Joshi
Abstract Traumatic brain injury (TBI) is not only an acute condition but also a chronic disease with long-term consequences. Intracranial hematomas are considered the primary consequences that occur in TBI and may have devastating effects that may lead to mass effect on the brain and eventually cause secondary brain injury. Emergent detection of hematoma in computed tomography (CT) scans and assessment of three major determinants, namely, location, volume, and size, is crucial for prognosis and decision-making, and artificial intelligence (AI) using deep learning techniques, such as convolutional neural networks (CNN) has received extended attention after demonstrations that it could perform at least as well as humans in imaging classification tasks. This article conducts a comparative review of medical and technological literature to update and establish evidence as to how technology can be utilized rightly for increasing the efficiency of the clinical workflow in emergency cases. A systematic and comprehensive literature search was conducted in the electronic database of PubMed and Google Scholar from 2013 to 2023 to identify studies related to the automated detection of intracranial hemorrhage (ICH). Inclusion and exclusion criteria were set to filter out the most relevant articles. We identified 15 studies on the development and validation of computer-assisted screening and analysis algorithms that used head CT scans. Our review shows that AI algorithms can prioritize radiology worklists to reduce time to screen for ICH in the head scans sufficiently and may also identify subtle ICH overlooked by radiologists, and that automated ICH detection tool holds promise for introduction into routine clinical practice.
摘要创伤性脑损伤(TBI)不仅是一种急性疾病,而且是一种具有长期后果的慢性疾病。颅内血肿被认为是创伤性脑损伤的主要后果,可能具有毁灭性的影响,可能导致脑肿块效应,最终导致继发性脑损伤。在计算机断层扫描(CT)中紧急检测血肿并评估三个主要决定因素,即位置、体积和大小,对于预后和决策至关重要,而使用深度学习技术的人工智能(AI),如卷积神经网络(CNN),在证明它至少可以在成像分类任务中表现得与人类一样好后,受到了广泛的关注。本文对医学和技术文献进行了比较回顾,以更新和建立关于如何正确利用技术来提高急诊病例临床工作流程效率的证据。通过2013 - 2023年在PubMed和Google Scholar电子数据库中进行系统、全面的文献检索,找出颅内出血(ICH)自动检测相关的研究。设置纳入和排除标准以过滤出最相关的文章。我们确定了15项关于使用头部CT扫描的计算机辅助筛选和分析算法的开发和验证的研究。我们的综述表明,人工智能算法可以优先考虑放射学工作清单,以充分减少在头部扫描中筛查脑出血的时间,也可以识别被放射科医生忽视的细微脑出血,并且自动化脑出血检测工具有望引入常规临床实践。
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引用次数: 1
Steroids and Traumatic Brain Injury: Time to Revisit? 类固醇和创伤性脑损伤:是时候重新审视了?
IF 0.2 Pub Date : 2023-06-27 DOI: 10.1055/s-0043-1769804
G. Prasad, D. Agarwal
Secondary insults such as brain edema are an important and relatively common event occurring after traumatic brain injury (TBI), leading to consequences such as raised intracranial pressure and cerebral herniation. Further, posttraumatic in fl ammatory changes are known to signi fi cantly contribute to neuronal dysfunction
脑水肿等继发性损伤是创伤性脑损伤(TBI)后发生的重要且相对常见的事件,可导致颅内压升高和脑疝等后果。此外,创伤后炎性改变被认为是神经元功能障碍的重要因素
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引用次数: 0
期刊
Indian Journal of Neurotrauma
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