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Effect of Transcranial Direct Current Stimulation on Motor Recovery in Altered Conscious Patients after Traumatic Brain Injury and Cerebrovascular Accident: A Randomized Clinical Trial 经颅直流电刺激对外伤性脑损伤和脑血管意外后意识改变患者运动恢复的影响:一项随机临床试验
IF 0.2 Pub Date : 2023-03-01 DOI: 10.1055/s-0043-1761937
Raj Kumar, Suraj Kumar, H. Prajapati, G. Potturi, Rahul Sharma
Abstract Background and Purpose  Altered levels of consciousness resulting from a vascular insult to the brain can vary from confusion to coma. A disruption in the function of the brain stem reticular activating system in the brain stem or both cerebral hemispheres and thalami causes coma. This study is aimed at finding the effect of transcranial direct current stimulation (tDCS) on motor recovery in altered conscious patients after traumatic brain injury and cerebrovascular accident. Materials and Methods  A total of 100 patients admitted to the neurology and neurosurgery unit of the university hospital were screened and 40 subjects who satisfied inclusion criteria were recruited and randomly divided into two groups, group A (experimental) ( n  = 20) and group B (control)(n = 20), by computerized randomization. Written informed consent was taken from all the caregivers before recruitment. After taking the preliminary assessment, anodal tDCS is given to the motor area (C3/C4 ipsilesional), sensory area (P3/P4 ipsilesional), and left dorsolateral prefrontal cortex (F3) according to the 10/20 electroencephalogram montage for two sessions of 20 min/day for 7 consecutive days. Routine physiotherapy was also given the same as group B. Results  At baseline, there were no significant group differences in the baseline characteristics. The groups passed the normality test. The results were tested for statistical significance between the groups by Mann–Whitney U test and by one-way analysis of variance and Tukey Honest Significant Difference for post-hoc comparison; the results were statistically different with p -value less than 0.05 with a large effect size. Conclusion  We conclude, based on the results of this study, that tDCS can be effective in motor recovery in altered consciousness patients. It is noninvasive, cost-effective with minimal contraindications, and does not interfere with other modalities in the intensive care unit. Hence, it can be administered safely under the supervision of a qualified therapist.
背景与目的脑血管损伤引起的意识水平改变可从意识模糊到昏迷。脑干网状激活系统在脑干或大脑半球和丘脑的功能中断导致昏迷。本研究旨在探讨经颅直流电刺激(tDCS)对外伤性脑损伤和脑血管意外后意识改变患者运动恢复的影响。材料与方法筛选大学附属医院神经内科神经外科收治的患者100例,选取符合纳入标准的患者40例,采用计算机随机化方法随机分为A组(试验组)20例和B组(对照组)20例。招募前获得所有护理人员的书面知情同意。经初步评估后,按10/20脑电图蒙太奇对运动区(C3/C4同侧)、感觉区(P3/P4同侧)、左背外侧前额叶皮质(F3)进行阳极tDCS,每次20分钟/天,连续7天。常规物理治疗与b组相同。结果基线时,各组基线特征无显著差异。各组均通过正态性检验。采用Mann-Whitney U检验,事后比较采用单因素方差分析和Tukey Honest显著性差异检验;结果有统计学差异,p值< 0.05,效应量较大。结论基于本研究的结果,我们认为tDCS对意识改变患者的运动恢复是有效的。它是非侵入性的,成本效益低,禁忌症最小,并且不会干扰重症监护病房的其他模式。因此,它可以在合格治疗师的监督下安全地进行。
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引用次数: 0
Outcome in TBI Patients with Early Physiotherapy and Post-discharge Rehabilitation: Indian Experience TBI患者早期物理治疗和出院后康复的疗效:印度经验
IF 0.2 Pub Date : 2023-02-16 DOI: 10.1055/s-0042-1759852
Vijayasekhar Venkata Manda, Rajesh Pathi, K. Swaroop, T. Phaneeswar, K. Satyavaraprasad
Abstract Introduction  Traumatic brain injury (TBI) is a major cause of death and disability worldwide and early initiation of physiotherapy with continuing rehabilitation may improve outcomes. Methods  All adult TBI patients with GCS 5–12 admitted from May 2018 to December 2019 were included. Early physiotherapy was initiated before the fifth day of admission and continued post discharge. Patients and families were educated in a rehabilitation program with printed handouts and video clips. All patients are followed up via telephone/video calls after discharge. We assessed the Glasgow Outcome Score (GOS) and disability at 15, 30, and 90 days post discharge, and 180 days follow-up was also suggested but only a few (38) patients reported. Data were compared with matched patients treated in previous years. Results  A total of 1,233 patients were studied. At 3-month follow-up by telephonic and video calls, GOS 5 was noted (63.7%; 174/ 273) in 2019 compared with (41.3%; 41/ 98) in 2018. The number of discharges increased after initiation of physiotherapy and rehabilitation programs (38%; 288/759 in 2019 versus 24%; 115/474 in 2018). Post-discharge deaths were also less (5.9%; 17/288) in 2019 compared with (14.8%; 17/115) in 2018. Conclusion  Early rehabilitation and post-discharge therapy are associated with improved outcomes of TBI patients. Refinements in data collection and communication improve patient follow-up and functional outcomes.
外伤性脑损伤(TBI)是世界范围内死亡和残疾的主要原因,早期开始物理治疗并持续康复可以改善预后。方法纳入2018年5月至2019年12月收治的所有GCS 5-12级成人TBI患者。入院第5天前开始早期物理治疗,出院后继续进行。病人和家属在康复计划中接受了打印的讲义和视频剪辑的教育。所有患者出院后均通过电话/视频随访。我们在出院后15、30和90天评估格拉斯哥预后评分(GOS)和残疾,并建议进行180天的随访,但只有少数(38)例患者报告。数据与前几年治疗的匹配患者进行比较。结果共纳入1233例患者。通过电话和视频随访3个月,GOS 5 (63.7%);174/ 273),而2019年为(41.3%;41/ 98)。在开始物理治疗和康复计划后,出院人数增加(38%;2019年288/759比24%;2018年为115/474)。出院后死亡率也较低(5.9%;17/288),相比之下(14.8%;17/115)。结论早期康复和出院后治疗可改善创伤性脑损伤患者的预后。数据收集和交流的改进改善了患者的随访和功能结果。
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引用次数: 0
Practical Challenges in the Management and Outcome of Unknown Patients with Head Injury 未知颅脑损伤患者治疗和预后的实际挑战
IF 0.2 Pub Date : 2023-02-16 DOI: 10.1055/s-0042-1759871
M. Vijayasekhar, P. Rajesh, K. Swaroop, M.P.A. Babu Nagendra, Satyavaraprasad Kadali
Abstract Background  Majority of road accidents are treated at nearby private hospitals. Head injury patients whose identity is not established are invariably being treated at government hospitals. The factors influencing the management and outcome of such unknown patients are possible only in government hospitals. Limited studies are available related to these unknown patients. Objective  This study attempted to analyze the management issues in such patients and tried to find solutions that will improve the outcome. Methods  It was an observational study over 2 years. All patients whose identity could not be established at admission were studied. Standard traumatic brain injury protocols were followed. Issues and challenges in managing these patients were noted. Many challenges popped up once patient was shifted out of intensive care unit and were studied. Results  Eighty-five patients were studied with male preponderance. Common age group was 41 to 60 years. The main cause of head injury was road traffic accident. Seventy-six patients were severely injured. Acute subdural hematomas was the most common computed tomography finding (36 patients). Sixty-nine patients were managed conservatively and 16 needed surgery. Forty-nine patients died in hospital, and other patients recovered well. Twenty-two patients were discharged home and 11 took discharge against medical advice after being identified by relatives. None were accommodated into destitute homes even after recovery. Conclusion  Unknown patients usually have poor outcome with more deaths in spite of standard care. Their management is fraught with challenges. They need special care for which staff should be motivated; hospital must have good network to establish identity.
背景大多数道路交通事故在附近的私立医院接受治疗。身份不明的头部受伤患者总是在政府医院接受治疗。只有在公立医院才有可能了解影响此类未知患者治疗和预后的因素。与这些未知患者相关的研究有限。目的分析该类患者的管理问题,寻求改善治疗效果的方法。方法采用2年多的观察性研究。所有入院时无法确定身份的患者均被研究。遵循标准的创伤性脑损伤方案。注意到管理这些患者的问题和挑战。患者从重症监护病房移出并进行研究后,出现了许多挑战。结果85例,男性为主。常见年龄组为41至60岁。造成头部损伤的主要原因是道路交通事故。76名患者严重受伤。急性硬膜下血肿是最常见的计算机断层扫描发现(36例)。69例患者采用保守治疗,16例需要手术治疗。49名患者在医院死亡,其他患者恢复良好。22名病人出院回家,11名病人经家属确认后不遵医嘱出院。即使在康复后,也没有人被安置到贫困的家庭。结论不明原因患者经标准治疗后预后较差,死亡率较高。他们的管理充满了挑战。他们需要特别照顾,员工应该受到激励;医院必须有良好的网络来建立身份。
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引用次数: 1
Complications of Decompressive Craniectomy: A Case-Based Review 减压颅骨切除术的并发症:一项基于病例的回顾
IF 0.2 Pub Date : 2023-02-09 DOI: 10.1055/s-0043-1760724
Sivaraman Kumarasamy, K. Garg, H. Gurjar, Kokkula Praneeth, Rajesh Meena, R. Doddamani, Amandeep Kumar, Shashwat Mishra, V. Tandon, Pankaj Singh, D. Agrawal
Abstract Background  Decompressive craniectomy (DC) is a frequently performed procedure to treat intracranial hypertension following traumatic brain injury (TBI) and stroke. DC is a salvage procedure that reduces mortality at the expense of severe disability and compromises the quality of life. The procedure is not without serious complications. Methods  We describe the complications following DC and its management in a case-based review in this article. Results  Complications after DC are classified as early or late complications based on the time of occurrence. Early complication includes hemorrhage, external cerebral herniation, wound complications, CSF leak/fistula, and seizures/epilepsy. Contusion expansion, new contralateral epidural, and subdural hematoma in the immediate postoperative period mandate surgical intervention. It is necessary to repeat non-contrast CT head at 24 hours and 48 hours following DC. Late complication includes subdural hygroma, hydrocephalus, syndrome of the trephined, bone resorption, and falls on the unprotected cranium. An early cranioplasty is an effective strategy to mitigate most of the late complications. Conclusions  DC can be associated with a number of complications. One should be aware of the possible complications, and timely intervention is required.
背景减压颅骨切除术(DC)是治疗创伤性脑损伤(TBI)和脑卒中后颅内高压的常用手术方法。DC是一种救助性程序,以牺牲严重残疾和损害生活质量为代价降低死亡率。手术并非没有严重的并发症。方法在本文中,我们以病例为基础回顾描述DC后的并发症及其处理。结果根据发生时间将DC术后并发症分为早期并发症和晚期并发症。早期并发症包括出血、脑外疝、伤口并发症、脑脊液漏/瘘和癫痫发作/癫痫。术后立即出现挫伤扩大、对侧硬膜外血肿和硬膜下血肿,需要手术干预。有必要在DC后24小时和48小时重复非对比CT头。晚期并发症包括硬脑膜下水瘤、脑积水、骨骺综合征、骨吸收和落在无保护的颅骨上。早期颅骨成形术是减轻大多数晚期并发症的有效策略。结论:DC可与多种并发症相关。人们应该意识到可能出现的并发症,并需要及时干预。
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引用次数: 0
Delayed Posttraumatic Tension Pneumocephalus: Case Report and Review of Literature 迟发性创伤后紧张性脑气:1例报告及文献回顾
IF 0.2 Pub Date : 2023-02-09 DOI: 10.1055/s-0043-1760726
C. Jain, Ajinkya Rewatkar, A. Roy, B. Indira Devi
Abstract Delayed tension pneumocephalus is a rare entity. Twelve cases of posttraumatic delayed tension pneumocephalus have been reported. This study is a case report of a patient presenting with delayed posttraumatic tension pneumocephalus, and highlights the nuances of management.
摘要迟发性张力性气头是一种罕见的疾病。本文报告了12例创伤后迟发性张力性脑积水。本研究是一个病例报告的病人表现为迟发性创伤后紧张性脑气,并强调管理的细微差别。
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引用次数: 0
Competency-Based Medical Education in Neurotrauma and Neurocritical Care 以能力为基础的神经创伤与神经危重症医学教育
IF 0.2 Pub Date : 2023-02-01 DOI: 10.1055/s-0043-1760721
Tariq Janjua, A. Agrawal, A. Pacheco-Hernandez, Y. Picón-Jaimes, I. Lozada‐Martínez, L. Moscote-Salazar
Training at the level of undergraduate and postgraduate (including fellowship) in neurotrauma and neurointensive care has been gaining more relevance. A key factor for this trend is the fact that traumatic brain injury is a public health problem.1 One of the new paradigms in education is the incorporation of the concept of medical education based on competencies.2Medical education requires the development of multiple skills on the part of the trainee that will result in benefit to address this public health problem.3,4 The competency-based medical training center is the key for trainees and the learning requirements. In contrast, when the development of competencies is established, the training andevaluationprocesses are individualized toachieve training objectives.Here thequestionarisesaboutwhat is themodel for competency-based training? Competence can be staged as the performance of an individual in a certain activity that is the productof the learningprocess. This requires the integrationof knowledge, skills, and attitudes adapted to the social context where it operates. The next question to address is if a training model based on competencies in neurotrauma and neurointensive care is valid? Competency-based education has been considered for training in critical care, in thiswaywe believe that given the complexity of medical care in neurotrauma and neurointensive care, this learning model encompasses all the care processes of the neurotrauma patient. From pre-hospital care, emergency management, transfer to hospitalization, neurointensive care, neurorehabilitation, and follow-up can be adapted to the competency-based learning model. We still need to addresswhat strategies can be established to implement a competency-based training model in neurotrauma and neurointensive care. Among the strategies that can be used are medical simulation, clinical case simulation in neurotrauma, and repeated evaluation. These strategies will increase interest and focus among the trainee in the management of patients with traumatic brain injury. The simulation of neurosurgical procedures and/or interventions in neurotrauma and simulation of procedures such as central line insertion are a few examples to be utilized for different trainees based upon the field of training they belong to. The data gathered from neurointensive care especially neurotrauma has to be utilized in real-time for the education, testing, simulation, and publication by the trainee (►Fig. 1). Periodic feedback should also include noncognitive elements such as student motivation, strengthening learning styles, and individualized aspects of each student. Also, human training stimulates ethical considerations of patient management andmakes the resident and specialist a respectful, analytical, and prudent human being. In conclusion, medical education in neurotrauma and neurointensive care is a multidisciplinary process. There are multiple key players in the process and all of them need to work in
在神经创伤和神经重症监护方面的本科和研究生(包括奖学金)水平的培训已经获得更多的相关性。造成这种趋势的一个关键因素是,创伤性脑损伤是一个公共卫生问题在教育的新范式之一是纳入基于能力的医学教育的概念。医学教育要求受训人员发展多种技能,这将有利于解决这一公共卫生问题。3、4以能力为本的医学培训中心是学员学习的关键,也是学习的要求。相反,当能力发展确立后,培训和评估过程是个性化的,以实现培训目标。这里的问卷是关于能力培训的模式是什么?能力可以表现为个人在某一活动中的表现,这是学习过程的产物。这就需要将知识、技能和态度结合起来,使之适应其所处的社会环境。下一个要解决的问题是基于神经创伤和神经重症监护能力的培训模式是否有效?以能力为基础的教育已被考虑用于重症监护的培训,因此我们认为,鉴于神经外伤和神经重症监护的医疗护理的复杂性,这种学习模式涵盖了神经外伤患者的所有护理过程。从院前护理、急诊管理、转院、神经重症监护、神经康复和随访,都可以适应基于能力的学习模式。我们仍然需要解决在神经创伤和神经重症监护中建立以能力为基础的培训模式的策略。可采用的策略包括医学模拟、神经外伤的临床病例模拟和重复评估。这些策略将增加学员对创伤性脑损伤患者管理的兴趣和关注。神经外科手术和/或神经创伤干预的模拟和中央静脉导管插入等程序的模拟是基于不同培训领域的不同受训者使用的几个例子。从神经重症监护,特别是神经外伤中收集的数据必须实时用于受训者的教育、测试、模拟和发表。1).定期反馈还应包括非认知因素,如学生动机、强化学习风格和每个学生的个性化方面。此外,人类培训激发了对患者管理的道德考虑,使住院医生和专家成为一个受人尊敬、善于分析和谨慎的人。总之,神经创伤和神经重症监护的医学教育是一个多学科的过程。在这个过程中有多个关键角色,他们都需要以一种综合的方式工作,以培养未来的顶尖临床医生。这些受训者将继续维护和发展项目,其中一些人将取代关键人物,继续为未来的受训者提供教育和培训。
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引用次数: 0
Arrogance in Neurosurgery and Neurocritical Care: A Barrier to Effective Teamwork 神经外科和神经危重症护理中的傲慢:有效团队合作的障碍
IF 0.2 Pub Date : 2023-02-01 DOI: 10.1055/s-0043-1760722
L. Moscote-Salazar, W. Florez-Perdomo, A. Pacheco-Hernandez, Sara Carolina Granados-Mendoza, Tariq Janjua
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引用次数: 0
Optimism Bias in Neurocritical Care and Neurotrauma: The Proof is in the Pudding! 乐观偏见在神经危重症护理和神经创伤:证据是在布丁!
IF 0.2 Pub Date : 2023-02-01 DOI: 10.1055/s-0043-1760725
Tariq Janjua, L. Moscote-Salazar
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引用次数: 0
Decision Fatigue and Neurosurgeons' Clinical Decision Making: An Enemy in the Shadow 决策疲劳与神经外科医生的临床决策:阴影中的敌人
IF 0.2 Pub Date : 2023-02-01 DOI: 10.1055/s-0043-1760723
L. Moscote-Salazar, W. Florez-Perdomo, A. Pacheco-Hernandez, Tariq Janjua
Decision fatigue is a recognized phenomenon in healthcare psychology. Prolonged activities can lead to stress and fatigue, a familiar term in neurocognition. This is called decision fatigue; it is related to the ability to make the best decisions that decline with the course of the day. There are three key attributes to be included in this process; behavioral, cognitive, and physiological. 1 The management of the neurosurgical patient is a complex process. Multiple fi elds of medicine have shown that there is this decision fatigue due to multiple complex processes in place to practice medicine. As the US president correctly said, “… I am trying to pare down decisions. I don ’ t want to make decisions about what I am eating or wearing. Because I have too many other decisions to make. You need to focus your decision-making energy …” . 2 The pandemic of COVID-19 has shown that this enemy is real and bedside intensive care nurses were the most impacted. 3 The practice of surgery is also known to have decision fatigue.Apatientwhoisseenattheendoftheworkinghoursof orthopedic
决策疲劳是保健心理学中公认的现象。长时间的活动会导致压力和疲劳,这是神经认知学中一个熟悉的术语。这被称为决策疲劳;它与做出最佳决策的能力有关,而这种能力会随着时间的推移而下降。在这个过程中有三个关键属性需要包含;行为,认知和生理。神经外科病人的管理是一个复杂的过程。多个医学领域已经表明,由于医学实践中的多个复杂过程,存在这种决策疲劳。正如这位美国总统正确地说过的那样:“……我正在努力减少决策。”我不想决定我吃什么或穿什么。因为我要做的决定太多了。你需要集中精力做决策……”COVID-19大流行表明,这个敌人是真实存在的,床边重症监护护士受到的影响最大。手术实践也被称为决策疲劳。Apatientwhoisseenattheendoftheworkinghoursof整形
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引用次数: 0
Clinico-Etiological Profile of Children Admitted with Head Injury in a Tertiary Health Care Centre During the COVID Pandemic COVID大流行期间在三级卫生保健中心入院的头部损伤儿童的临床病因学概况
IF 0.2 Pub Date : 2023-01-23 DOI: 10.1055/s-0042-1760448
Lemin Mohan Puravankara, A. Peethambaran
Abstract Background  The mechanism of injury, type of pathology, mode of management and specific problems, in the pediatric age group make these a unique population. The COVID-19 pandemic and lockdown caused a significant reduction in the number of road traffic accidents during the same period and the resultant number of head injuries in children. Methods  This was a descriptive study of 76 consecutive pediatric patients admitted with head injury between June and December 2020. Children under 18 years with head injury admitted in our hospital were included. Results  The most common etiology of pediatric head injury was found to be fall from height (61.8%) followed by road traffic accidents (27.6%). The most common age group affected was 1 to 5 years with a mean of 6.3 ± 5 years. Road traffic accidents were commonly seen in the 15 to 18 age group. The Glasgow Outcome Score (GOS) of 1 (death) was seen in one patient (1.3%) and low disability in 98.7% of patients. Conclusion  Falls formed the most important cause of pediatric head injury during this pandemic, and carefulness on the part of parents can help avoid dangerous consequences for the children. Recovery with minimal disability was observed in approximately all cases in this study. The number of severe traumatic brain injury was very low in this study. This can be attributed to the COVID-19 pandemic causing significant reduction in road traffic accidents and the number of severe head injury
背景儿童年龄组的损伤机制、病理类型、处理方式和具体问题使其成为一个独特的人群。2019冠状病毒病大流行和封锁导致同期道路交通事故数量大幅减少,儿童头部受伤人数也因此减少。方法:对2020年6月至12月期间连续入院的76例头部损伤儿科患者进行描述性研究。纳入我院收治的18岁以下颅脑损伤儿童。结果儿童头部损伤最常见的病因是高空坠落(61.8%),其次是道路交通事故(27.6%)。最常见的发病年龄为1 ~ 5岁,平均6.3±5岁。道路交通事故常见于15至18岁年龄组。1例(1.3%)患者的格拉斯哥预后评分(GOS)为1分(死亡),98.7%的患者残疾程度较低。结论:在本次大流行期间,跌倒是儿童头部损伤的最重要原因,家长的谨慎可以帮助避免儿童的危险后果。在本研究中,几乎所有病例都观察到最小残疾的恢复。本研究中严重外伤性脑损伤发生率极低。这可归因于2019冠状病毒病大流行导致道路交通事故和严重头部受伤人数大幅减少
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引用次数: 0
期刊
Indian Journal of Neurotrauma
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