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Comparison of Muscle Mass Indexes According to Protein Intake in Obese Patients 肥胖患者肌肉质量指数与蛋白质摄入的比较
Pub Date : 2016-12-30 DOI: 10.7570/KJO.2016.25.4.215
Mingyeong Heo, Yeon Joo Lee, Yongsoon Park
Obesity is a disease in which body fat excessively accumulates to the extent that health is negatively affected. Obesity is reported to be associated with diseases including diabetes, hypertension, hypercholesterolemia, asthma, arthritis, heart disease, stroke, endometrial cancer, breast cancer, and colorectal cancer. According to a 2014 report by the World Health Organization (WHO), the obese population has more than doubled since 1980, and now comprises approximately 13% of the global adult population (11% and 15% of the male and female populations, respectively). This is also the case in Korea, where the obese population is steadily increasing at a higher rate than that noted previously. In 2013, the prevalence of adult obesity, defined as body mass index (BMI) ≥ 25 kg/m, was approximately 32.5% (37.6% for men and 27.5% for women). Hence, a third of the Korean adult population is obese. Generally, BMI and waist circumference are used as indexes for obesity. Obesity is defined as a BMI ≥ 30 kg/m in Western countries and ≥ 25 kg/m in Asia-Pacific countries; the latter definition is used in Korea. Additionally, waist circumference and waist-hip ratio are used as indexes for abdominal obesity. The Korean Society for the Study of Obesity gives the definition of abdominal obesity as waist circumference ≥ 90 cm for men and ≥ 85 cm for women. BMI does not provide information regarding body fat mass or fat-free mass, but recent studies have reported that metabolic syndrome is associated with body fat and fat-free masses. Of several body composition measures, fat-free mass in particular has an inverse Jshaped association with all-cause mortality, and the level of fat-free Comparison of Muscle Mass Indexes According to Protein Intake in Obese Patients
肥胖是一种身体脂肪过度积累,对健康产生负面影响的疾病。据报道,肥胖与糖尿病、高血压、高胆固醇血症、哮喘、关节炎、心脏病、中风、子宫内膜癌、乳腺癌和结直肠癌等疾病有关。根据世界卫生组织(世卫组织)2014年的一份报告,自1980年以来,肥胖人口增加了一倍多,目前约占全球成年人口的13%(分别占男性和女性人口的11%和15%)。韩国的情况也是如此,肥胖人口的增长速度比之前提到的要快。2013年,成人肥胖率(定义为体重指数(BMI)≥25 kg/m)约为32.5%(男性37.6%,女性27.5%)。因此,韩国成年人口的三分之一是肥胖人口。一般来说,BMI和腰围是肥胖的指标。肥胖在西方国家定义为BMI≥30 kg/m,在亚太国家定义为BMI≥25 kg/m;韩国使用的是后一种定义。此外,腰围和腰臀比作为腹部肥胖的指标。韩国肥胖学会对腹部肥胖的定义是,男性腰围≥90厘米,女性腰围≥85厘米。身体质量指数没有提供关于体脂量或无脂量的信息,但最近的研究表明,代谢综合征与体脂量和无脂量有关。在几种身体成分测量中,无脂肪量与全因死亡率呈负j型相关,肥胖患者的无脂肪肌肉质量指数与蛋白质摄入量的比较
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引用次数: 0
The Inhibitory Effect of Testosterone on PPARγ-induced Adipogenesis 睾酮对ppar γ诱导的脂肪生成的抑制作用
Pub Date : 2016-06-30 DOI: 10.7570/KJO.2016.25.2.68
Sunhyo Jeong
Background: Peroxisome proliferator-activated receptor γ (PPARγ) plays a major role in adipocyte differentiation. Testosterone is well known for inhibiting adipocyte metabolism in men. To investigate the inhibitory mechanism of testosterone on adipogenesis, this study evaluated the effects of testosterone on PPARγ expression and activity in adipocytes using in vitro approaches. Methods: After differentiated 3T3-L1 adipocytes were treated with PPARγ agonist troglitazone and sex hormone testosterone, the effects of testosterone on troglitazone-induced triglyceride accumulation and expression of genes involved in adipogenesis were investigated. We also inves-tigated whether testosterone regulates troglitazone-induced PPARγ reporter activity in 3T3-L1 preadipocytes. Results: Testosterone decreased triglyceride accumulation in differentiated 3T3-L1 cells compared with the vehicle treated control group. Testosterone also decreased the expression of PPARγ mRNA as well as PPARγ dependent adipocyte-specific genes, such as adipocyte fatty acid binding protein and tumor necrosis factor α. Moreover, testosterone treatment inhibited triglyceride accumulation, and the expression of PPARγ and adipocyte-specific genes caused by troglitazone in differentiated 3T3-L1 cells. Testosterone decreased troglitazone-induced PPARγ reporter activity. Also, treatment with testosterone led to an inhibition of troglitazone-induced PPARγ reporter activity in PPARγ and androgen receptor (AR) expressed 3T3-L1 preadipocytes. Conclusion: These results suggest that testosterone interferes with the actions of PPARγ on adipogensis by an AR-dependent component. In addition, this study may have provided valuable molecular and biological insights regarding testosterone therapy in obese hypogonadal men.
背景:过氧化物酶体增殖物激活受体γ (PPARγ)在脂肪细胞分化中起重要作用。众所周知,睾酮能抑制男性脂肪细胞代谢。为了探讨睾酮对脂肪形成的抑制机制,本研究采用体外方法评估了睾酮对脂肪细胞中PPARγ表达和活性的影响。方法:用PPARγ激动剂曲格列酮和性激素睾酮处理分化后的3T3-L1脂肪细胞,观察睾酮对曲格列酮诱导的甘油三酯积累和脂肪形成相关基因表达的影响。我们还研究了睾酮是否调节曲格列酮诱导的3T3-L1前脂肪细胞中PPARγ报告细胞的活性。结果:与对照组相比,睾酮降低了分化3T3-L1细胞中甘油三酯的积累。睾酮还降低了PPARγ mRNA以及PPARγ依赖性脂肪细胞特异性基因(如脂肪细胞脂肪酸结合蛋白和肿瘤坏死因子α)的表达。此外,睾酮治疗抑制了甘油三酯的积累,以及由曲格列酮引起的分化3T3-L1细胞中PPARγ和脂肪细胞特异性基因的表达。睾酮降低曲格列酮诱导的PPARγ报告活性。此外,睾酮治疗导致曲格列酮诱导的PPARγ和雄激素受体(AR)表达3T3-L1前脂肪细胞中PPARγ报告细胞活性的抑制。结论:这些结果表明睾酮通过ar依赖成分干扰PPARγ在脂肪形成中的作用。此外,这项研究可能为肥胖性腺功能低下男性的睾酮治疗提供了有价值的分子和生物学见解。
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引用次数: 2
The Associations between Discordance of Body Image and Physical Activities among Adults Aged 19 to 64 Years: Based on the Data from 2010 Community Health Survey 19 ~ 64岁成人身体形象不和谐与体育活动的关系——基于2010年社区健康调查数据
Pub Date : 2014-12-01 DOI: 10.7570/KJO.2014.23.4.274
I. Chun, S. Ryu, Jong Park, M. Han, Seong-Woo Choi, Dae-Sik Ko
Background: The purposes of this study were to evaluate the discordance of body image and to identify the associations between discordance of body image and physical activities among adults aged 19 to 64 years. Methods: The study included 172,132 subjects from the 2010 Community Health Survey. The discordance of body image was defined as incongruence between body perception with actual body size based on body mass index (concordance vs. discordance: under, over). Physical activities were categorized as moderate to vigorous physical activity and walking activity. The data were analyzed using chi-square test and multiple logistic regression analysis. Results: Subjects who showed concordance between their body perception and their actual body size were 74.9%, while those who showed discordance between the two factors were 25.1% (under-: 20.1%, over-: 5.0%). Among subjects who showed discordance in their body image, the adjusted Odds ratio (OR) for moderate to vigorous physical activity was 0.97 (95% CI, 0.94-1.00), and OR for walking activity was 0.92 (95% CI, 0.90-0.95). Subjects with under-estimated body image had lower OR for walking activity 0.93 (95% CI, 0.90-0.96). Subjects with over-estimated body image had lower ORs for both moderate to vigorous physical activity 0.69 (95% CI, 0.63-0.76) and walking activity 0.89 (95% CI, 0.84-0.95). Conclusion: These findings support the evidence that incongruence in body image serves as a barrier in engaging physical activity. Proper recognition of one’s own body perception is needed in order to improve physical activity.
背景:本研究旨在评估19 ~ 64岁成人身体意象不一致性,并探讨身体意象不一致性与体育活动之间的关系。方法:本研究纳入2010年社区健康调查的172,132名受试者。身体形象的不一致被定义为身体感知与基于身体质量指数的实际身体尺寸之间的不一致(一致vs.不一致:低于,超过)。体育活动分为中度至剧烈体育活动和步行活动。资料采用卡方检验和多元logistic回归分析。结果:74.9%的被试对自己的体型感知与实际体型一致,25.1%的被试对自己的体型感知与实际体型不一致(低于20.1%,高于5.0%)。在身体形象不一致的受试者中,中等至剧烈运动的调整比值比(OR)为0.97 (95% CI, 0.94-1.00),步行活动的调整比值比(OR)为0.92 (95% CI, 0.90-0.95)。低估身体形象的受试者步行活动的OR较低,为0.93 (95% CI, 0.90-0.96)。高估身体形象的受试者在中度到剧烈运动的or值较低,分别为0.69 (95% CI, 0.63-0.76)和0.89 (95% CI, 0.84-0.95)。结论:这些发现支持了身体形象不一致是参与体育活动的障碍的证据。正确认识自己的身体知觉是提高体育锻炼的必要条件。
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引用次数: 6
Vitamin D and Obesity 维生素D与肥胖
Pub Date : 2014-12-01 DOI: 10.7570/KJO.2014.23.4.236
C. Jung, J. Mok
Vitamin D affects not only musculoskeletal health but also a range of nonskeletal diseases such as cancer, obesity, metabolic syndrome, type 2 diabetes and cardiovascular disease. Vitamin D deficiency and obesity have been recognized as pandemic diseases with much health consequences. The ‘cause-effect’ relationship of vitamin D to obesity has been the area of much recent activity. There is consistent association in the published literature between higher body mass index (BMI) and lower 25-hydroxyvitamin D (25(OH)D) concentrations, but the mechanisms are not fully understood. Although recent studies suggest that low serum vitamin D is the consequence of obesity, the results from randomized controlled trials are still scarce and inconclusive to establish the relationship between vitamin D and obesity. Moreover, the role of vitamin D in the pathophysiology of obesity is still debatable and there is little evidence for a direct effect of vitamin D supplementation on body weight. Therefore, randomized large-scale double-blind controlled trials are needed in the future to clearly establish the effects of vitamin D in obesity.
维生素D不仅影响肌肉骨骼健康,还影响一系列非骨骼疾病,如癌症、肥胖、代谢综合征、2型糖尿病和心血管疾病。维生素D缺乏和肥胖已被认为是具有许多健康后果的流行病。维生素D与肥胖之间的“因果关系”是最近研究的热点。在已发表的文献中,较高的身体质量指数(BMI)与较低的25-羟基维生素D (25(OH)D)浓度之间存在一致的关联,但其机制尚未完全了解。虽然最近的研究表明低血清维生素D是肥胖的后果,但随机对照试验的结果仍然很少,无法确定维生素D与肥胖之间的关系。此外,维生素D在肥胖病理生理中的作用仍有争议,几乎没有证据表明补充维生素D对体重有直接影响。因此,未来需要随机大规模双盲对照试验来明确维生素D对肥胖的影响。
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引用次数: 2
Effects of Resistance Exercise Training on Childhood Obesity 抗阻运动训练对儿童肥胖的影响
Pub Date : 2014-09-01 DOI: 10.7570/KJO.2014.23.3.141
Minsuk Oh, YoonMyung Kim, S. Suh, J. Jeon
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引用次数: 1
The Inhibitory Effect of Quercetin on Adipose Tissue Inflammation in Mice Fed on a High-fat Diet 槲皮素对高脂饮食小鼠脂肪组织炎症的抑制作用
Pub Date : 2014-09-01 DOI: 10.7570/KJO.2014.23.3.170
Chu‐Sook Kim, R. Yu
Background: Obesity-induced adipose inflammation contributes to the development of metabolic disorders such as insulin resistance and type 2 diabetes. In this study, we investigated whether quercetin, a naturally occurring phytochemical, can attenuate adipose tissue inflammation in obese mice. Methods: Male C57BL/6 mice were randomly assigned into either control (RD, N=6), high fat diet (HFD, N=6), or HFD supplemented with 0.05% quercetin (HFD+Que, N=6) groups and treated with their respective diets for 9 weeks. The inflammatory cytokine pro-teins were measured by ELISA, and macrophage populations were determined by immunohistochemistry. The inflammatory receptors and downstream signaling molecules were measured by qPCR and western blot, respectively. Results: We show here that in an HFD-fed mice model, quercetin supplementation reduced adipose tissue weight without affecting HFD-induced body weight gain. Quercetin supplementation reduced expression of inflammatory cytokines (TNF-α, MCP-1, MIP-1α) and macrophage accumulation (F4/80) in adipose tissue of an HFD-fed mice. Quercetin also suppressed the expression of inflammatory receptors (CCR2, TLR4, TNFRSF9) and the activation of downstream inflammatory signaling molecules (JNK, NF-κB) in adipose tissue. Conclusion: These findings indicate that quercetin can reduce adipose inflammatory responses in mice exposed to HFD by inhibiting inflammatory cytokines production, inflammatory receptor expression and their signaling pathway. Quercetin may be useful for preventing HFD-induced adipose tissue inflammation.
背景:肥胖引起的脂肪炎症有助于代谢紊乱的发展,如胰岛素抵抗和2型糖尿病。在这项研究中,我们研究了槲皮素,一种天然产生的植物化学物质,是否可以减轻肥胖小鼠的脂肪组织炎症。方法:将雄性C57BL/6小鼠随机分为对照组(RD, N=6)、高脂饲料组(HFD, N=6)和高脂饲料中添加0.05%槲皮素组(HFD+Que, N=6),分别饲喂9周。炎性细胞因子pro-teins ELISA测定,通过免疫组织化学方法确定和巨噬细胞的数量。分别用qPCR和western blot检测炎症受体和下游信号分子。结果:我们在这里表明,在饲喂hfd的小鼠模型中,补充槲皮素减少了脂肪组织的重量,而不影响hfd引起的体重增加。槲皮素补充剂降低炎性细胞因子的表达(TNF -α,MCP-1, MIP-1α)和巨噬细胞积累(F4/80) HFD-fed老鼠的脂肪组织。槲皮素抑制炎症受体的表达(CCR2, TLR4 TNFRSF9)和下游的激活炎症信号分子(物、NF -κB)在脂肪组织中。结论:槲皮素可通过抑制炎症因子的产生、炎症受体的表达及其信号通路,降低HFD小鼠的脂肪炎症反应。槲皮素可能有助于预防hfd引起的脂肪组织炎症。
{"title":"The Inhibitory Effect of Quercetin on Adipose Tissue Inflammation in Mice Fed on a High-fat Diet","authors":"Chu‐Sook Kim, R. Yu","doi":"10.7570/KJO.2014.23.3.170","DOIUrl":"https://doi.org/10.7570/KJO.2014.23.3.170","url":null,"abstract":"Background: Obesity-induced adipose inflammation contributes to the development of metabolic disorders such as insulin resistance and type 2 diabetes. In this study, we investigated whether quercetin, a naturally occurring phytochemical, can attenuate adipose tissue inflammation in obese mice. Methods: Male C57BL/6 mice were randomly assigned into either control (RD, N=6), high fat diet (HFD, N=6), or HFD supplemented with 0.05% quercetin (HFD+Que, N=6) groups and treated with their respective diets for 9 weeks. The inflammatory cytokine pro-teins were measured by ELISA, and macrophage populations were determined by immunohistochemistry. The inflammatory receptors and downstream signaling molecules were measured by qPCR and western blot, respectively. Results: We show here that in an HFD-fed mice model, quercetin supplementation reduced adipose tissue weight without affecting HFD-induced body weight gain. Quercetin supplementation reduced expression of inflammatory cytokines (TNF-α, MCP-1, MIP-1α) and macrophage accumulation (F4/80) in adipose tissue of an HFD-fed mice. Quercetin also suppressed the expression of inflammatory receptors (CCR2, TLR4, TNFRSF9) and the activation of downstream inflammatory signaling molecules (JNK, NF-κB) in adipose tissue. Conclusion: These findings indicate that quercetin can reduce adipose inflammatory responses in mice exposed to HFD by inhibiting inflammatory cytokines production, inflammatory receptor expression and their signaling pathway. Quercetin may be useful for preventing HFD-induced adipose tissue inflammation.","PeriodicalId":432482,"journal":{"name":"The Korean Journal of Obesity","volume":"148 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134522625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Association between Smoking Status and Metabolic Syndrome in Men 男性吸烟状况与代谢综合征的关系
Pub Date : 2014-06-30 DOI: 10.7570/KJO.2014.23.2.99
J. Oh
Background: Smoking is associated with increased insulin resistance. Insulin resistance is a common feature of metabolic syndrome. The purpose of this study was to examine the association between smoking and metabolic syndrome among Korean men. Methods: Subjects for this cross-sectional study included 6,281 males over the age of 20 who visited the hospital for a health check-up. Anthropometric measurements and biochemical studies were conducted. Smoking status of subjects was obtained by self-reported questionnaires. The metabolic syndrome was defined according to the revised NCEP-ATP III criteria. The risk of metabolic syndrome and its components according to smoking status was examined using the multiple logistic regression analysis. Results: The overall prevalence of metabolic syndrome was 28.8% and it was significantly (P 20 pack year smokers the OR was 1.11 (95% CI, 0.91-1.33), 1.28 (95% CI, 1.071.54), and 1.38 (95% CI, 1.12-1.70), respectively, compared with nonsmokers. Conclusion: These findings show that former smokers and current smokers with greater than 10 pack year history are at significantly higher risk for metabolic syndrome compared with never smokers. Especially, the risk of metabolic syndrome in current smokers is positively associated with the number of pack years of smoking.
背景:吸烟与胰岛素抵抗增加有关。胰岛素抵抗是代谢综合征的共同特征。本研究的目的是研究吸烟与韩国男性代谢综合征之间的关系。方法:本横断面研究的对象包括6281名20岁以上到医院进行健康检查的男性。进行了人体测量和生化研究。研究对象的吸烟状况采用自述问卷。根据修订后的NCEP-ATP III标准定义代谢综合征。采用多元logistic回归分析对不同吸烟状况的代谢综合征发病风险及其相关因素进行分析。结果:代谢综合征的总患病率为28.8%,与不吸烟者相比,吸烟者的OR分别为1.11 (95% CI, 0.91-1.33)、1.28 (95% CI, 1.071.54)和1.38 (95% CI, 1.12-1.70)。结论:这些发现表明,与从不吸烟者相比,过去吸烟者和现在吸烟者有超过10包年的吸烟史,患代谢综合征的风险明显更高。特别是,当前吸烟者患代谢综合征的风险与吸烟年数呈正相关。
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引用次数: 22
Relationship between Body Fat Percent and Obesity Indices in Short Stature Women 身材矮小女性体脂率与肥胖指数的关系
Pub Date : 2014-06-01 DOI: 10.7570/KJO.2014.23.2.93
Jiwon Myung, Y. Han, Kyung Bin Min, Jun Young Kwon, Y. Roh, M. Choi
Background: Body mass index (BMI) is frequently used as an index to assess obesity. However, BMI has limitations in accurately predicting body fat mass in terms of stature intervals. Therefore, we analyzed the relationship between body fat % and three obesity indices; BMI, waist circumference (WC) and waist circumference to height ratio (WHtR) in short stature women. Methods: Korean women (N= 317) of 19-60 years of age with short stature, defined by 1-10th percentile stature, were enrolled as subjects. Correlation analysis was used to evaluate relationship of body fat % and the obesity indices. After defining obesity as body fat % over 30, area under curve (AUC), sensitivity and specificity of the indices were obtained by receiver operating characteristic (ROC) analysis. Additionally, optimal cutoff values of the indices and sensitivity, specificity at that time were obtained. Results: There was statistically significant and positive correlation between body fat % and the indices (r= 0.804 for BMI, 0.763 for WC, 0.768 for WHtR). All indices showed moderate diagnostic accuracy according to AUC (0.888 for BMI, 0.885 for WC, 0.889 for WHtR). Both sensitivity and specificity of WHtR was high (0.758, 0.885 respectively). Specificity of BMI and WC was higher than WHtR but, their sensitivity was lower than WHtR. The optimal cutoff values were 22.6 kg/m for BMI, 75.5 cm for WC, 0.50 for WHtR. Conclusion: Among the obesity indices, we observed WHtR 0.5 to be superior to BMI 25 or WC 85 cm as an index to diagnose obesity in women of short stature.
背景:身体质量指数(BMI)经常被用作评估肥胖的指标。然而,BMI在准确预测身高间隔的体脂量方面存在局限性。因此,我们分析了体脂率与3项肥胖指标的关系;身高较矮女性的BMI、腰围(WC)和腰围与身高比(WHtR)。方法:选取韩国女性(N= 317)为研究对象,年龄19-60岁,身高1-10百分位。采用相关分析评价体脂率与肥胖指数的关系。将肥胖定义为体脂%超过30后,通过受试者工作特征(ROC)分析得出指标的曲线下面积(AUC)、敏感性和特异性。同时,得出该指标的最佳截止值以及当时的敏感性、特异性。结果:体脂%与各指标呈显著正相关(BMI r= 0.804, WC r= 0.763, WHtR r= 0.768)。所有指标的AUC诊断准确率均为中等(BMI 0.888, WC 0.885, WHtR 0.889)。WHtR的敏感性和特异性均较高(分别为0.758、0.885)。BMI和WC的特异性高于WHtR,敏感性低于WHtR。最佳临界值BMI为22.6 kg/m, WC为75.5 cm, WHtR为0.50。结论:在肥胖指标中,我们观察到WHtR 0.5优于BMI 25或WC 85 cm作为诊断矮个子女性肥胖的指标。
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引用次数: 1
Effects of Weight Management Program for Middle Aged Women with Metabolic Syndrome Risk Factors 体重管理方案对中年妇女代谢综合征危险因素的影响
Pub Date : 2014-06-01 DOI: 10.7570/KJO.2014.23.2.106
Si Hwa Kim, O. Yu, Moon‐Sun Byun, Y. Cha, Tae-sun Park
program in 46 aged women (including 16 halfway dropouts) with BMI < 23 kg/m 2 in Jeollabukdo region. The anthropometry, blood pressure, serum biochemistry, DEXA, dietary behavior, knowledge on nutrition, and nutritional intake data of the subjects were assessed before and after undergoing the weight management program. Results: Bodyweight, BMI, and body fat percentage of the subjects were significantly (P < 0.001) decreased after the weight management program. Also the blood glucose (P < 0.01) and LDL-cholesterol (P < 0.05) levels were significantly decreased, whereas HDL-cholesterol (P < 0.001) was significantly increased. The DEXA results indicated that body fat mass and body fat percentage were significantly decreased, but the lean mass increased significantly (P < 0.001). Furthermore, improvements were noted in 10 out of the 15 dietary behavior questions and 6 out of 15 nutrition knowledge’s questions (P < 0.05). Energy intake was decreased significantly (P < 0.001). Conclusion: This study suggests that weight management program improves many obesity related parameters as in body fat mass and serum lipid biochemistry thus, promoting a positive health effect.
以全北道地区体重指数< 23 kg/ m2的46名老年女性(包括16名中途辍学者)为对象。在实施体重管理计划前后,评估受试者的人体测量、血压、血清生化、DEXA、饮食行为、营养知识和营养摄入数据。结果:体重管理方案实施后,受试者的体重、BMI和体脂率均显著降低(P < 0.001)。血糖(P < 0.01)和低密度脂蛋白胆固醇(P < 0.05)水平显著降低,高密度脂蛋白胆固醇(P < 0.001)水平显著升高。DEXA结果显示,体脂质量和体脂率显著降低,而瘦质量显著增加(P < 0.001)。15个饮食行为题中有10个、15个营养知识题中有6个有改善(P < 0.05)。能量摄入显著降低(P < 0.001)。结论:体重管理方案可改善肥胖相关指标,如体脂量和血脂生化指标,对健康有积极影响。
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引用次数: 7
Association between Depression and Physical Fitness, Body Fatness and Serum Vitamin D in Elderly Population 老年人群抑郁与体质、体脂及血清维生素D的关系
Pub Date : 2014-06-01 DOI: 10.7570/KJO.2014.23.2.125
Inhwan Lee, Youngyun Jin, Jin-Kyung Cho, Jin-Hwan Yoon, H.-S. Kang
Background: This study examined the association of depression with functional physical fitness, body fatness, and serum vitamin D in elderly persons. Methods: This was a cross sectional study involving 21 men with mean age of 75.4 ± 6.8 years and 96 women with mean age of 75.0 ± 6.8 years. Body mass index, percent body fat, and waist circumference were measured according to a standardized protocol. Functional physical fitness including strength, cardiorespiratory endurance, agility, dynamic balance and flexibility was measured in accordance to a standardized fitness assessment manual. Serum levels of vitamin D, lipoprotein lipids, fasting glucose and insulin were measured with standardized procedures. Korean form of Geriatric Depression Scale (K-GDS) was used to assess depression level and status. Pearson correlation analyses were used to calculate bivariate correlations between measured variables. Multiple linear regression analyses were used to identify any independent predictors for K-GDS-based depression score. Results: Depression score was significantly and inversely associated with functional physical fitness including strength (P < 0.001), cardiorespiratory endurance (P < 0.001), agility (P = 0.002) and dynamic balance (P < 0.001). A similar trend in correlation was observed between depression and serum vitamin D level. Multiple linear regression analyses showed that strength (P < 0.001), cardiorespiratory endurance (P = 0.005), and percent body fat (P = 0.045) were significant independent predictors of depression in this study population. Conclusion: The finding of the study suggest that fitness promotion along with a healthy diet habit should be a key component of intervention against depression in elderly persons.
背景:本研究考察了老年人抑郁与功能性体能、体脂和血清维生素D的关系。方法:采用横断面研究,男性21例,平均年龄75.4±6.8岁,女性96例,平均年龄75.0±6.8岁。身体质量指数、体脂率和腰围是根据标准化的方案测量的。功能性体能包括力量、心肺耐力、敏捷性、动态平衡和柔韧性,根据标准化体能评估手册进行测量。血清维生素D、脂蛋白脂、空腹血糖和胰岛素水平用标准化程序测量。采用韩式老年抑郁量表(K-GDS)评估抑郁水平和状态。Pearson相关分析用于计算测量变量之间的双变量相关性。采用多元线性回归分析确定基于k - gds的抑郁评分的独立预测因子。结果:抑郁评分与功能体能包括力量(P < 0.001)、心肺耐力(P < 0.001)、敏捷性(P = 0.002)和动态平衡(P < 0.001)呈显著负相关。抑郁症与血清维生素D水平之间也存在类似的相关性。多元线性回归分析显示,力量(P < 0.001)、心肺耐力(P = 0.005)和体脂百分比(P = 0.045)是该研究人群抑郁的显著独立预测因子。结论:本研究结果提示,促进健康的饮食习惯应是干预老年人抑郁症的关键组成部分。
{"title":"Association between Depression and Physical Fitness, Body Fatness and Serum Vitamin D in Elderly Population","authors":"Inhwan Lee, Youngyun Jin, Jin-Kyung Cho, Jin-Hwan Yoon, H.-S. Kang","doi":"10.7570/KJO.2014.23.2.125","DOIUrl":"https://doi.org/10.7570/KJO.2014.23.2.125","url":null,"abstract":"Background: This study examined the association of depression with functional physical fitness, body fatness, and serum vitamin D in elderly persons. Methods: This was a cross sectional study involving 21 men with mean age of 75.4 ± 6.8 years and 96 women with mean age of 75.0 ± 6.8 years. Body mass index, percent body fat, and waist circumference were measured according to a standardized protocol. Functional physical fitness including strength, cardiorespiratory endurance, agility, dynamic balance and flexibility was measured in accordance to a standardized fitness assessment manual. Serum levels of vitamin D, lipoprotein lipids, fasting glucose and insulin were measured with standardized procedures. Korean form of Geriatric Depression Scale (K-GDS) was used to assess depression level and status. Pearson correlation analyses were used to calculate bivariate correlations between measured variables. Multiple linear regression analyses were used to identify any independent predictors for K-GDS-based depression score. Results: Depression score was significantly and inversely associated with functional physical fitness including strength (P < 0.001), cardiorespiratory endurance (P < 0.001), agility (P = 0.002) and dynamic balance (P < 0.001). A similar trend in correlation was observed between depression and serum vitamin D level. Multiple linear regression analyses showed that strength (P < 0.001), cardiorespiratory endurance (P = 0.005), and percent body fat (P = 0.045) were significant independent predictors of depression in this study population. Conclusion: The finding of the study suggest that fitness promotion along with a healthy diet habit should be a key component of intervention against depression in elderly persons.","PeriodicalId":432482,"journal":{"name":"The Korean Journal of Obesity","volume":"167 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131815888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
期刊
The Korean Journal of Obesity
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