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Applying FHIR in Remote Consultation in Dermatology: Interoperability of Information for Digital Dermatoscope FHIR在皮肤科远程会诊中的应用:数字皮肤镜信息的互操作性
Tzu-Fang Peng, Hung-Wen Chiu
Because of the Coronavirus disease and the problem of uneven distribution of physicians between urban and rural areas, telemedicine is widely adopted, including tele-dermatology. However, there is still no formal and consistent format for telemedicine data exchange in Taiwan. In 2021, Ministry of Health and Welfare (MOHW) of Taiwan has announced that the National Electronic Medical Record Exchange Center (EEC) should follow Fast Health Care Interoperability Resources (FHIR) based on Health Level 7 (HL7) in Taiwan. Dermatoscope has become a significant tool for diagnosis in dermatology. It is used in diagnosing benign and malignant skin tumors, seborrheic keratosis, malignant melanoma, squamous cell carcinoma, and basal cell carcinoma, etc. With the advancement of medical optical imaging, dermoscope has become a convenient, portable, non-invasive, diagnostic instrument. In this study, we set FHIR standards for the interoperability of information for digital dermatoscope in teleconsultation, and built a FHIR-based teleconsultation system. There were two stages: Setting the FHIR standard for information of digital dermatoscope in teleconsultation and sharing information between teleconsultation system and the FHIR server.
由于新冠肺炎疫情和城乡医生分布不均的问题,远程医疗被广泛采用,包括远程皮肤科。然而,台湾目前仍没有正式且一致的远程医疗数据交换格式。台湾卫生福利部(MOHW)于2021年宣布,国家电子病历交换中心(EEC)应遵循台湾基于健康等级7 (HL7)的快速医疗互操作资源(FHIR)。皮肤镜已成为皮肤科诊断的重要工具。用于诊断良恶性皮肤肿瘤、脂溢性角化病、恶性黑色素瘤、鳞状细胞癌、基底细胞癌等。随着医学光学成像技术的进步,皮肤镜已成为一种方便、便携、无创的诊断仪器。在本研究中,我们为远程会诊中数字皮镜信息的互操作性制定了FHIR标准,并构建了一个基于FHIR的远程会诊系统。制定远程会诊数字皮镜信息的FHIR标准和远程会诊系统与FHIR服务器之间的信息共享两个阶段。
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引用次数: 0
Are Africa on the Right Track to Prevent COVID-19? Reflections from African Business Magazine's Coverage of the COVID-19 Pandemic 非洲在预防COVID-19方面走对了吗?《非洲商业》杂志对2019冠状病毒病大流行报道的思考
Kuo-Kuang Huang
African Business Magazine is one of market leaders in providing country supplements, industry reports and market intelligence on Africa. African Business was first published in January 1982. Its headquarters are in London. The monthly magazine covers business events, special reports which discuss specific sectors and industries across Africa. Since the outbreak of the COVID-19 Pandemic in March 2020, the monthly magazine published 64 reports or articles related to the COVID-19 status in Africa continent. This study tries to retrieve from these reports published on the magazine since March 2022 to study local perspectives on the pandemic event. Africa government's responses to the spread of the COVID-19 and impacts to economy and public health retrieved from the mass medias will be compared with WHO's guidelines under different stages since outbreak of the pandemic to verify whether African's COVID-19 prevention performance can be trusted. This study would add African's viewpoints to prevent COVID-19 under the limits of fragile health system to the existed pandemic studies.
《非洲商业杂志》是提供非洲国家增刊、行业报告和市场情报的市场领导者之一。《非洲商业》于1982年1月首次出版。它的总部设在伦敦。该月刊涵盖商业事件,特别报道,讨论非洲各地的特定部门和行业。自2020年3月新冠肺炎大流行爆发以来,该月刊共发表了64篇与非洲大陆新冠肺炎疫情有关的报告或文章。本研究试图从该杂志自2022年3月以来发表的这些报告中检索,以研究当地对大流行事件的看法。将从媒体上检索到的非洲政府应对新冠肺炎疫情传播的情况以及对经济和公共卫生的影响与世卫组织自疫情爆发以来不同阶段的指导方针进行比较,验证非洲预防新冠肺炎的表现是否值得信任。本研究将为现有的流行病研究增加非洲在脆弱的卫生系统限制下预防COVID-19的观点。
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引用次数: 0
Develop a Natural Language Processing Pipeline to Automate Extraction of Periodontal Disease Information from Electronic Dental Clinical Notes 开发一种自然语言处理管道,从电子牙科临床记录中自动提取牙周病信息
J. Patel, R. Rao, R. Brandon, Vishnu Iyer, J. Albandar, M. Tellez, J. Krois, Huanmei Wu
Introduction: Periodontal disease (PD) is one of the most prevalent dental diseases, suffered by 80% of US adults. PD can be prevented if its etiologic and risk factors are identified and controlled early. Electronic dental record (EDR) data provide researchers a unique opportunity to develop prediction models that can provide personalized disease risk and treatment recommendations. However, 90% of important clinical information is documented only in the free-text format of EDR. The objective of this study was to develop natural language processing (NLP) applications to extract PD diagnoses, medical histories (e.g., cardiovascular diseases, diabetes), and social history (e.g., smoking) in a structured format for comprehensive follow-up periodontal research. Methods: We have developed a five-stage NLP pipeline. First, we retrieved both structured and non-structured data from the EDR using SQL queries. Next, we developed manual annotation guidelines using both the bottom-up and top-down approaches. The manual annotations were performed by experts in Step 3, which also built the gold standard data. Part of the gold standard data was used in a named entity recognition (NER) development (Step 4), and for additional validation (Step 5). Results: The SQL queries resulted in a cohort of 27,138 unique patients, each with multiple clinical notes. The manual annotation guidelines were based on 100 unique patients with 347 clinical notes to identify the writing patterns in our EDR system. Existing literature was also studied to develop manual annotation guidelines. For Step 3, two domain experts manually reviewed 4,000 clinical notes using the eHOST annotation tool. The evaluation showed 94.5% accuracy in extracting patients’ detailed PD diagnoses, CVD, smoking, and diabetes information from the EDR. Statistics of the extracted clinical notes improved our knowledge on periodontitis classification and other systemic diseases such as cardiovascular diseases (CVD) and diabetes. Conclusion: Our NLP pipeline increased the utilization of EDR for periodontal research from the free-text dental clinical notes. Hence, developing novel informatics methods such as NLP is critical for using EDR data optimally and efficiently for research.
牙周病(PD)是最普遍的牙齿疾病之一,80%的美国成年人患有此病。如果PD的病因和危险因素得到早期识别和控制,PD是可以预防的。电子牙科记录(EDR)数据为研究人员提供了一个独特的机会来开发预测模型,从而提供个性化的疾病风险和治疗建议。然而,90%的重要临床信息仅以电子病历的自由文本格式记录。本研究的目的是开发自然语言处理(NLP)应用程序,以结构化格式提取PD诊断,病史(如心血管疾病,糖尿病)和社会史(如吸烟),以进行全面的牙周随访研究。方法:我们开发了一个五阶段的NLP管道。首先,我们使用SQL查询从EDR检索结构化和非结构化数据。接下来,我们使用自底向上和自顶向下的方法开发了手动注释指南。手工注释由专家在步骤3中执行,该步骤也构建了金标准数据。部分金标准数据用于命名实体识别(NER)开发(步骤4)和额外验证(步骤5)。结果:SQL查询产生27,138个独特患者的队列,每个患者都有多个临床记录。手工标注指南是基于100名独特患者的347份临床笔记,以确定我们的EDR系统中的书写模式。同时研究现有文献,制定手工标注指南。对于步骤3,两位领域专家使用eHOST注释工具手动审查了4,000份临床记录。评估显示,从EDR中提取患者详细的PD诊断、CVD、吸烟和糖尿病信息的准确率为94.5%。统计提取的临床记录提高了我们对牙周炎分类和其他全身性疾病如心血管疾病(CVD)和糖尿病的认识。结论:我们的NLP管道增加了EDR在牙周研究中的利用,这些EDR来自自由文本牙科临床记录。因此,开发新的信息学方法,如NLP,对于优化和有效地利用EDR数据进行研究至关重要。
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引用次数: 1
A New Poisoning Attacks on Deep Neural Networks 一种新的深度神经网络投毒攻击
Jung-Shian Li, Yen-Chu Peng, I. Liu, Chuan-Gang Liu
In healthcare field, many machine learning schemes have been applied in analyzing image content dataset. Among them, deep neural networks (DNNs), also known as deep learning, catches much attention. However, if deep neural networks are compromised by the attacker, medical diagnosis may be wrong, which leads to vital result. Recently, we find a new poisoning attack on DNNs may possibly happens due to poisoning dataset. This new poisoning attack, Category Diverse attack, has better ability to paralyze DNNs. Our performance experiments show our Category diverse attack actually leads to large accuracy drop of DNNs. We hope this discovery can help the information experts can improve the medical dataset quality in the future.
在医疗保健领域,许多机器学习方案已经应用于图像内容数据集的分析。其中,深度神经网络(dnn)也被称为深度学习,备受关注。然而,如果深度神经网络被攻击者破坏,医疗诊断可能会错误,从而导致重大后果。最近,我们发现由于中毒数据集可能会发生一种新的针对dnn的中毒攻击。这种新的中毒攻击,类别多样化攻击,具有更好的麻痹dnn的能力。我们的性能实验表明,我们的分类多样化攻击实际上导致dnn的准确率大幅下降。我们希望这一发现可以帮助信息专家在未来提高医疗数据集的质量。
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引用次数: 1
Human Fall Detection Based on Unidirectional Multi-Scale Spatial Encoder and Bidirectional Temporal Decoder Neural Network 基于单向多尺度空间编码器和双向时间解码器神经网络的人体跌倒检测
Chi Ee Yeoh, Jyun-Guo Wang
According to a statistic report from World Health Organization (WHO), fall is the second leading cause of death. They even add that residents with a disability who live in the nursing home or chronic care facility have a higher risk for falls. Approximately 30 to 50% of them had encountered fall every year, about 40% of them had more than once. Based on a statistic report released by the National Health Insurance Administration of Taiwan in 2018, fall is the second leading cause of death for people above 65 years old. Based on the population record, Taiwan will turn Super-aged society in 2025. The increasing demand and recent success of deep learning technology in the various research fields, especially computer vision, encouraged us to develop a deep learning based fall detecting system. Through this system, we aim to reduce the detection time of falls. A Unidirectional Multi-Scale Spatial Encoder and Bidirectional Temporal Decoder neural network is proposed to enhance performance for human fall detection. Additionally, we also utilize an auxiliary dataset "UCF50" to enhance the model's spatial recognition ability. The proposed method was able to achieve accuracy of 99.7% and F1-score of 99.97 at URFD.
根据世界卫生组织(WHO)的一份统计报告,跌倒是第二大死亡原因。他们甚至补充说,住在养老院或慢性护理机构的残疾居民摔倒的风险更高。大约30%到50%的人每年都会遇到跌倒,大约40%的人不止一次。根据台湾国家医疗保险局2018年发布的统计报告,跌倒是65岁以上老年人的第二大死亡原因。根据人口记录,台湾将在2025年进入超老龄化社会。深度学习技术在各个研究领域,尤其是计算机视觉领域不断增长的需求和最近的成功,鼓励我们开发基于深度学习的跌倒检测系统。通过这个系统,我们的目标是减少跌倒的检测时间。为了提高人体跌倒检测的性能,提出了一种单向多尺度空间编码器和双向时间解码器神经网络。此外,我们还利用辅助数据集“UCF50”来增强模型的空间识别能力。该方法在URFD下的准确率为99.7%,f1评分为99.97。
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引用次数: 0
Rejuvenation through Collagen Induced with a Novel Picosecond Laser 新型皮秒激光诱导胶原蛋白再生
Putri Hendria Wardhan, C. Prakoeswa, M. Listiawan
Elderly population will continue to grow. Wrinkles are one of signs of skin aging because of the progressive loss of the dermal matrix content. Collagen is the most abundant dermal protein that it's content per unit area of skin surface decreases approximately 1% per year. The science and technology of modern engineering for wrinkle improvement has continued to evolve. Skin rejuvenation techniques for wrinkle repair have changed dramatically with the development of lasers. This study aimed to evaluate rejuvenation of wrinkle repair through collagen induction using a novel picosecond laser. Twenty subjects between 36 and 55 years old with wrinkle in the forearm were recruited. Before and 4 weeks after the subject was given treatment, a clinical examination and biopsy for histopathological examination was carried out as a pre and post-test evaluation, then treatment was carried out using a picosecond laser. Patients were predominantly female with a mean age of 42.5. At 1 month follow-up, a significant improvement was noted in wrinkle and collagen density (p<0.05). This picosecond laser was found to be effective in treating wrinkle through collagen induction which was confirmed by clinical and collagen density examination. It is believed that the high energy delivered by the picosecond laser is absorbed by intraepidermal melanin to form laser induced optical breakdown that converted into pressure waves that propagate into the dermis. This barotrauma may lead to changes in the dermis that result in collagen induction and dermal improvement. Picosecond laser is an effective option for rejuvenation through collagen induction.
老年人口将继续增长。皱纹是皮肤老化的标志之一,因为真皮基质含量的逐渐丧失。胶原蛋白是最丰富的真皮蛋白质,它的含量每单位面积的皮肤表面每年减少约1%。改善皱纹的现代工程科学技术不断发展。随着激光技术的发展,皱纹修复的皮肤再生技术发生了巨大的变化。本研究旨在评估利用新型皮秒激光诱导胶原蛋白修复皱纹的再生效果。招募了20名年龄在36至55岁之间、前臂有皱纹的受试者。治疗前和治疗后4周,分别进行临床检查和组织病理学检查,作为治疗前和治疗后的评估,然后进行皮秒激光治疗。患者以女性为主,平均年龄42.5岁。随访1个月,皱纹和胶原蛋白密度显著改善(p<0.05)。皮秒激光通过胶原诱导治疗皱纹有效,经临床和胶原密度检查证实。皮秒激光传递的高能量被表皮内黑色素吸收,形成激光诱导的光击穿,并转化为压力波传播到真皮层。这种气压创伤可能导致真皮的变化,从而导致胶原蛋白的诱导和真皮的改善。皮秒激光是通过胶原诱导恢复活力的有效选择。
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引用次数: 0
Mechanism of action of cognitive behavioral therapy on pain in adult women with major TMJ disorders 认知行为疗法治疗成年女性重度颞下颌关节障碍疼痛的作用机制
Shujun Dong, Yuqing Zhang, X. Cen, Xiaojing Li, Lixia Yu, Zhongjie Li, Xiaoqin Zhu
Abstract: Objective: To explore the intervention effect and mechanism of cognitive-behavioral therapy (CBT) in adult women with Temporomandibular disorders pain for over three months. Methods: Among the adult patients with temporomandibular joint disorders diagnosed for the first time from 2019 to 2021, randomly selected 24 in the supportive group and 23 in the CBT group with physiological treatment, eight, 50min/week/time paired psychological intervention, cortisol testing for one and three months of follow-up and efficacy question answered. Paired independent sample t-test, qualitative analysis discusses the effect and mechanism. Results: CBT had a significant effect on pain trends in chronic TMJ disorders in adult women (I / S= -1.15, P <0.001): self-growth, emotional management, and pain improvement; the supportive group was stress regulation and interpersonal relationship. Conclusion: Psychological intervention can effectively relieve pain; the higher pain value is better; different mechanisms have different treatments. For example, CBT in self-growth, emotional management, pain improvement, and supportive therapy in interpersonal improvement and stress adjustment enhances the psychological resilience of patients.
摘要:目的:探讨认知行为疗法(CBT)对3个月以上成年女性颞下颌紊乱性疼痛的干预效果及机制。方法:在2019 - 2021年首次诊断的成年颞下颌关节障碍患者中,随机选择支持组24例、CBT组23例进行生理治疗,8次、50min/周/次配对心理干预,进行1个月和3个月的皮质醇测试随访并回答疗效问题。配对独立样本t检验,定性分析探讨效果及机制。结果:CBT对成年女性慢性颞下颌关节疾病患者疼痛趋势有显著影响(I / S= -1.15, P <0.001):自我成长、情绪管理和疼痛改善;支持组为压力调节和人际关系。结论:心理干预能有效缓解疼痛;疼痛值越高越好;不同的机制有不同的处理方法。例如,在自我成长、情绪管理、疼痛改善方面的CBT,以及在人际关系改善和压力调节方面的支持治疗,都能增强患者的心理弹性。
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引用次数: 0
Proceedings of the 6th International Conference on Medical and Health Informatics 第六届医学与健康信息学国际会议论文集
{"title":"Proceedings of the 6th International Conference on Medical and Health Informatics","authors":"","doi":"10.1145/3545729","DOIUrl":"https://doi.org/10.1145/3545729","url":null,"abstract":"","PeriodicalId":432782,"journal":{"name":"Proceedings of the 6th International Conference on Medical and Health Informatics","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127343539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Proceedings of the 6th International Conference on Medical and Health Informatics
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