F. Abtahi, Mahkameh Farmanesh, A. Moaref, S. Shekarforoush
Background: Unlike left ventricular function, less attention has been paid to Right Ventricular (RV) function after Myocardial Infarction (MI). Objectives: The current study aimed to compare RV function in patients with inferior
{"title":"Right Ventricular Involvement in either Anterior or Inferior Myocardial Infarction","authors":"F. Abtahi, Mahkameh Farmanesh, A. Moaref, S. Shekarforoush","doi":"10.17795/ICRJ-10(2)67","DOIUrl":"https://doi.org/10.17795/ICRJ-10(2)67","url":null,"abstract":"Background: Unlike left ventricular function, less attention has been paid to Right Ventricular (RV) function after Myocardial Infarction (MI). Objectives: The current study aimed to compare RV function in patients with inferior","PeriodicalId":43653,"journal":{"name":"International Cardiovascular Research Journal","volume":"10 1","pages":"67-71"},"PeriodicalIF":0.2,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68175619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Cardiovascular diseases have various etiologies. Previous studies have come to contradictory results regarding the effects of Oral Contraceptive Pills (OCPs) on the risk of myocardial infarction, angina pectoris, and venous thrombosis. Thus, further investigation is required in this area. Objectives: This study aimed to determine the relationship between cardiovascular diseases and some risk factors in the women with a history of contraceptive pills
{"title":"Investigation of the Relationship between Myocardial Infarction, Angina Pectoris, and Venous Thrombosis and Some Risk Factors in the Women Suffering from Cardiovascular Diseases with a History of Contraceptive Pills Consumption","authors":"M. Akbarzade, N. Sharifi, N. Zare","doi":"10.17795/ICRJ-10(2)77","DOIUrl":"https://doi.org/10.17795/ICRJ-10(2)77","url":null,"abstract":"Background: Cardiovascular diseases have various etiologies. Previous studies have come to contradictory results regarding the effects of Oral Contraceptive Pills (OCPs) on the risk of myocardial infarction, angina pectoris, and venous thrombosis. Thus, further investigation is required in this area. Objectives: This study aimed to determine the relationship between cardiovascular diseases and some risk factors in the women with a history of contraceptive pills","PeriodicalId":43653,"journal":{"name":"International Cardiovascular Research Journal","volume":"108 1","pages":"77-83"},"PeriodicalIF":0.2,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68175669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
*Corresponding author: Ali Hosseinsabet, Cardiology Department, Tehran Heart Center, Karegar Shomali Avenue, Tehran, IR Iran, Tel/Fax: +98-2188029731, E-mail: ali_hosseinsabet@yahoo.com
{"title":"Cardiac Involvement with Diffuse Large B Cell Lymphoma","authors":"A. Hosseinsabet, Maryam Sotoudeh Anvary","doi":"10.17795/ICRJ-10(2)102","DOIUrl":"https://doi.org/10.17795/ICRJ-10(2)102","url":null,"abstract":"*Corresponding author: Ali Hosseinsabet, Cardiology Department, Tehran Heart Center, Karegar Shomali Avenue, Tehran, IR Iran, Tel/Fax: +98-2188029731, E-mail: ali_hosseinsabet@yahoo.com","PeriodicalId":43653,"journal":{"name":"International Cardiovascular Research Journal","volume":"10 1","pages":"102-103"},"PeriodicalIF":0.2,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68175028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dietary saturated and cholesterol are the cause of atherosclerosis and of calories from saturated fat, while 64% consumed 10 - 13% of calories from saturated fat. Conclusions : In this study, most of the CHD patients got low DQI scores. In general, CHD can be prevented. However, if precautions regarding lifestyle modification are not followed, CHD is expected to progress.
{"title":"Dietary Quality after Diagnosis of Coronary Heart Disease","authors":"U. Ozturk, Ö. Öztürk, Perran Toksoz","doi":"10.17795/ICRJ-10(2)72","DOIUrl":"https://doi.org/10.17795/ICRJ-10(2)72","url":null,"abstract":"Dietary saturated and cholesterol are the cause of atherosclerosis and of calories from saturated fat, while 64% consumed 10 - 13% of calories from saturated fat. Conclusions : In this study, most of the CHD patients got low DQI scores. In general, CHD can be prevented. However, if precautions regarding lifestyle modification are not followed, CHD is expected to progress.","PeriodicalId":43653,"journal":{"name":"International Cardiovascular Research Journal","volume":"10 1","pages":"72-76"},"PeriodicalIF":0.2,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68175624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Bezgin, C. Doğan, A. Karagöz, A. Elveran, C. Kaymaz
Cleft in the anterior mitral leaflet is an infrequent congenital anomaly most often encountered in association with other congenital heart defects. The importance of the lesion is that it is often a correctable cause of Mitral Regurgitation (MR).
{"title":"Cleft in the Anterior Mitral Valve Leaflet Assessed by Real-time 3D Echocardiography","authors":"T. Bezgin, C. Doğan, A. Karagöz, A. Elveran, C. Kaymaz","doi":"10.17795/ICRJ-10(2)99","DOIUrl":"https://doi.org/10.17795/ICRJ-10(2)99","url":null,"abstract":"Cleft in the anterior mitral leaflet is an infrequent congenital anomaly most often encountered in association with other congenital heart defects. The importance of the lesion is that it is often a correctable cause of Mitral Regurgitation (MR).","PeriodicalId":43653,"journal":{"name":"International Cardiovascular Research Journal","volume":"10 1","pages":"99-101"},"PeriodicalIF":0.2,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68175790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Shackebaei, F. Feizollahi, M. Hesari, G. Bahrami
Background : Hypertrophied hearts are susceptible to ischemic injury. Besides, cardiac vulnerability could be changed in the presence of diazepam. Objectives : The current study aimed to investigate the effect of diazepam on hypertrophied rats’ hearts in ischemia-reperfusion conditions. Materials and Methods : Male Wistar rats (body weight 210 - 270 gr) were administered with isoproterenol (4 mg/kg body weight, intraperitoneally for 7 days) alone or along with diazepam (1 and 5 mg/kg body weight, intraperitoneally for 5 days). The control rats received normal saline intraperitoneally. The animal s’ hearts were isolated according to langendorff setup and were passed through baseline, ischemia, and reperfusion stages. Then, cardiac mass index (ratio of heart weight to body weight) was measured. Cardiac functional parameters, including left ventricular developed pressure and rate pressure product, were also assessed at baseline and following ischemia. The data were analyzed using ANOVA and P < 0.05 was considered to be statistically significant. Results : Isoproterenol-induced cardiac hypertrophy was significantly reduced by both doses of diazepam compared to the group only treated with isoproterenol (P < 0.05) although it did not reach the control level. However, diazepam administration (1 and 5 mg/kg) did not change isoproterenol-induced exacerbated ischemia-reperfusion injury compared to the control group (P = 0.001 and P = 0.013, respectively). Conclusions : Diazepam relatively prevented the isoproterenol–induced cardiac hypertrophy in the animal model. This effect could be probably explained by the modification of oxidative stress and preservation of intracellular calcium concentration. Considering the common clinical usage of diazepam, as a peripheral benzodiazepine ligand, antihypertrophic effects of diazepam are recommended to be investigated in clinical trials.
{"title":"The Effect of Diazepam on the Function of Hypertrophied Rats’ Hearts in Ischemia-Reperfusion Conditions","authors":"D. Shackebaei, F. Feizollahi, M. Hesari, G. Bahrami","doi":"10.17795/ICRJ-10(2)89","DOIUrl":"https://doi.org/10.17795/ICRJ-10(2)89","url":null,"abstract":"Background : Hypertrophied hearts are susceptible to ischemic injury. Besides, cardiac vulnerability could be changed in the presence of diazepam. Objectives : The current study aimed to investigate the effect of diazepam on hypertrophied rats’ hearts in ischemia-reperfusion conditions. Materials and Methods : Male Wistar rats (body weight 210 - 270 gr) were administered with isoproterenol (4 mg/kg body weight, intraperitoneally for 7 days) alone or along with diazepam (1 and 5 mg/kg body weight, intraperitoneally for 5 days). The control rats received normal saline intraperitoneally. The animal s’ hearts were isolated according to langendorff setup and were passed through baseline, ischemia, and reperfusion stages. Then, cardiac mass index (ratio of heart weight to body weight) was measured. Cardiac functional parameters, including left ventricular developed pressure and rate pressure product, were also assessed at baseline and following ischemia. The data were analyzed using ANOVA and P < 0.05 was considered to be statistically significant. Results : Isoproterenol-induced cardiac hypertrophy was significantly reduced by both doses of diazepam compared to the group only treated with isoproterenol (P < 0.05) although it did not reach the control level. However, diazepam administration (1 and 5 mg/kg) did not change isoproterenol-induced exacerbated ischemia-reperfusion injury compared to the control group (P = 0.001 and P = 0.013, respectively). Conclusions : Diazepam relatively prevented the isoproterenol–induced cardiac hypertrophy in the animal model. This effect could be probably explained by the modification of oxidative stress and preservation of intracellular calcium concentration. Considering the common clinical usage of diazepam, as a peripheral benzodiazepine ligand, antihypertrophic effects of diazepam are recommended to be investigated in clinical trials.","PeriodicalId":43653,"journal":{"name":"International Cardiovascular Research Journal","volume":"10 1","pages":"89-94"},"PeriodicalIF":0.2,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68175740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Şen, S. Yılmaz, F. Ozcan, O. Ozeke, S. Çay, S. Topaloğlu, D. Aras, S. Aydoǧdu
Background : Coronary Slow Flow (CSF) is described as delayed opacification of the distal vasculature and angiographically Normal Coronary Arteries (NCA). Numerous studies have suggested that the interval from the peak to the end of electrocardiographic T wave (Tp-e) may correspond to transmural dispersion of repolarization and that increased Tp-e interval and Tp-e/QT ratio are associated with malignant ventricular arrhythmias. Objectives : The present study aimed to evaluate ventricular repolarization in patients with CSFby using Tp-e interval and Tp--e/QT ratio. Patients and Methods : This study was conducted on electrocardiographic parameters of 100 patients with angiographically proven NCA with CSF in all three coronary arteries and 100 patients with NCA without CSF. The patients were followed up for arrhythmias and clinical events. Results : Tp–e tail interval (120 ± 5.5 msn, 101 ± 3.9 msn; P < 0.001), Tp–e tangent interval (99 ± 4.0 msn, 78 ± 3.0 msn, P < 0.001), Tp-e tail/QT ratio (0.31 ± 0.004, 0.26 ± 0.003, P < 0.001), and Tp-e tangent/QT ratio (0.25 ± 0.003, 0.19 ± 0.003, P < 0.001) were significantly higher in the CSF patients compared to the NCA group. Rhythm holter analyses also showed that ventricular extrasystoles were higher (157 ± 22.5, 87 ± 11.9, P = 0.002) in the CSF group compared to the NCA group. Conclusions : Tp-e interval and Tp-e/QT ratio were significantly higher in the patients with CSF compared to the NCA group. important electrocardiographic parameter to predict arrhythmias in patients with coronary slow flow.
{"title":"The Relationship between Tpeak-end Interval Duration and Tpeak-end/QT Ratio, and Arrhythmias in Patients with Coronary Slow Flow","authors":"F. Şen, S. Yılmaz, F. Ozcan, O. Ozeke, S. Çay, S. Topaloğlu, D. Aras, S. Aydoǧdu","doi":"10.17795/ICRJ-10(2)84","DOIUrl":"https://doi.org/10.17795/ICRJ-10(2)84","url":null,"abstract":"Background : Coronary Slow Flow (CSF) is described as delayed opacification of the distal vasculature and angiographically Normal Coronary Arteries (NCA). Numerous studies have suggested that the interval from the peak to the end of electrocardiographic T wave (Tp-e) may correspond to transmural dispersion of repolarization and that increased Tp-e interval and Tp-e/QT ratio are associated with malignant ventricular arrhythmias. Objectives : The present study aimed to evaluate ventricular repolarization in patients with CSFby using Tp-e interval and Tp--e/QT ratio. Patients and Methods : This study was conducted on electrocardiographic parameters of 100 patients with angiographically proven NCA with CSF in all three coronary arteries and 100 patients with NCA without CSF. The patients were followed up for arrhythmias and clinical events. Results : Tp–e tail interval (120 ± 5.5 msn, 101 ± 3.9 msn; P < 0.001), Tp–e tangent interval (99 ± 4.0 msn, 78 ± 3.0 msn, P < 0.001), Tp-e tail/QT ratio (0.31 ± 0.004, 0.26 ± 0.003, P < 0.001), and Tp-e tangent/QT ratio (0.25 ± 0.003, 0.19 ± 0.003, P < 0.001) were significantly higher in the CSF patients compared to the NCA group. Rhythm holter analyses also showed that ventricular extrasystoles were higher (157 ± 22.5, 87 ± 11.9, P = 0.002) in the CSF group compared to the NCA group. Conclusions : Tp-e interval and Tp-e/QT ratio were significantly higher in the patients with CSF compared to the NCA group. important electrocardiographic parameter to predict arrhythmias in patients with coronary slow flow.","PeriodicalId":43653,"journal":{"name":"International Cardiovascular Research Journal","volume":"10 1","pages":"84-88"},"PeriodicalIF":0.2,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68175678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Amoozgar, N. Homayoon, G. Ajami, M. Borzouee, S. Cheriki, M. Edraki
Background: Syncope is a common problem among children. Objectives: This cross-sectional study aimed to determine the epidemiological characteristics of children with syncope and clarify the outcome of managements in Imam Reza Pediatrics Cardiology Clinic affiliated to Shiraz University of Medical Sciences, the main referral center for pediatric patients with syncope in south of Iran. Patents and Methods: This cross-sectional, descriptive–analytical study was conducted on all the children referred with transient loss of consciousness and positive head up tilt test. A total of 243 children (132 girls and 111 boys) were recruited from April 2007 to April 2013. The patients’ treatment outcomes were determined through telephone interviews. All the statistical analyses were performed using the SPSS statistical software (version 16.0). Besides, P 3 seconds during syncope. Conclusions: This study indicated that similar to other populations, syncope was more prevalent among girls in our area. Additionally, the most common cause was mixed type of vasovagal syncope. Medical therapy along with offering the patients to increase water and salt intake and do counter pressure physical maneuvers were effective in reduction of the recurrence of syncope.
{"title":"Epidemiological Characteristics and Clinical Outcome of Syncope in Children; A Report from Shiraz, Iran","authors":"H. Amoozgar, N. Homayoon, G. Ajami, M. Borzouee, S. Cheriki, M. Edraki","doi":"10.17795/ICRJ-10(1)24","DOIUrl":"https://doi.org/10.17795/ICRJ-10(1)24","url":null,"abstract":"Background: Syncope is a common problem among children. Objectives: This cross-sectional study aimed to determine the epidemiological characteristics of children with syncope and clarify the outcome of managements in Imam Reza Pediatrics Cardiology Clinic affiliated to Shiraz University of Medical Sciences, the main referral center for pediatric patients with syncope in south of Iran. Patents and Methods: This cross-sectional, descriptive–analytical study was conducted on all the children referred with transient loss of consciousness and positive head up tilt test. A total of 243 children (132 girls and 111 boys) were recruited from April 2007 to April 2013. The patients’ treatment outcomes were determined through telephone interviews. All the statistical analyses were performed using the SPSS statistical software (version 16.0). Besides, P 3 seconds during syncope. Conclusions: This study indicated that similar to other populations, syncope was more prevalent among girls in our area. Additionally, the most common cause was mixed type of vasovagal syncope. Medical therapy along with offering the patients to increase water and salt intake and do counter pressure physical maneuvers were effective in reduction of the recurrence of syncope.","PeriodicalId":43653,"journal":{"name":"International Cardiovascular Research Journal","volume":"10 1","pages":"24-28"},"PeriodicalIF":0.2,"publicationDate":"2016-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68175274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Z. Haghighi, A. Amin, Mitra Chitsazan, S. Taghavi, N. Naderi, M. Abdollahi, K. Mozaffari
Background: Endomyocardial Biopsy (EMB) is the gold standard test for diagnosis of acute allograft cardiac rejection. Objectives: The present study aimed to assess the role of echocardiographic parameters in discriminating patients with and without evidence of acute cardiac allograft rejection. Materials and Methods: In the present cross-sectional study, using convenience sampling, 63 EMB specimens were collected from the patients who had undergone biatrial orthotropic cardiac transplantation. The mean age of the recipients and donors was 30.46 ± 9.49 and 24.55 ± 7.64 years, respectively. There were 51(81%) male recipients and 39(62%) male donors. Echocardiographic examination was performed within the 24 hours of EMB. The data were entered into the SPSS statistical software, version 19 and were analyzed by chi-square test, student’s t-test, and one-way ANOVA as appropriated. All the data were two-tailed and P < 0.05 was considered to be statistically significant. Results: Among the 63 EMB specimens evaluated in the present study, mild and moderate acute rejections were seen in 19(30%) and 5(8%) cases, respectively. On Doppler examination, the three groups (without rejection, with mild rejection, and with moderate acute rejection) were significantly different only regarding trans-tricuspid E wave (P = 0.040). Pulsed-wave Tissue Doppler Imaging (TDI) also revealed a significant difference between the patients with and without allograft rejection regarding early diastolic tricuspid and mitral annular motion velocities (P = 0.005 and P = 0.02, respectively). Conclusions: It seems that echocardiographic parameters, including TDI, might be adjunct to, rather than substitution for, EMB findings for early diagnosis of acute allograft rejection.
{"title":"Evaluation of the Role of Conventional and Tissue Doppler Imaging Echocardiography in Detection of Acute Cardiac Allograft Rejection in Heart Transplant Recipients","authors":"Z. Haghighi, A. Amin, Mitra Chitsazan, S. Taghavi, N. Naderi, M. Abdollahi, K. Mozaffari","doi":"10.17795/ICRJ-10(1)35","DOIUrl":"https://doi.org/10.17795/ICRJ-10(1)35","url":null,"abstract":"Background: Endomyocardial Biopsy (EMB) is the gold standard test for diagnosis of acute allograft cardiac rejection. Objectives: The present study aimed to assess the role of echocardiographic parameters in discriminating patients with and without evidence of acute cardiac allograft rejection. Materials and Methods: In the present cross-sectional study, using convenience sampling, 63 EMB specimens were collected from the patients who had undergone biatrial orthotropic cardiac transplantation. The mean age of the recipients and donors was 30.46 ± 9.49 and 24.55 ± 7.64 years, respectively. There were 51(81%) male recipients and 39(62%) male donors. Echocardiographic examination was performed within the 24 hours of EMB. The data were entered into the SPSS statistical software, version 19 and were analyzed by chi-square test, student’s t-test, and one-way ANOVA as appropriated. All the data were two-tailed and P < 0.05 was considered to be statistically significant. Results: Among the 63 EMB specimens evaluated in the present study, mild and moderate acute rejections were seen in 19(30%) and 5(8%) cases, respectively. On Doppler examination, the three groups (without rejection, with mild rejection, and with moderate acute rejection) were significantly different only regarding trans-tricuspid E wave (P = 0.040). Pulsed-wave Tissue Doppler Imaging (TDI) also revealed a significant difference between the patients with and without allograft rejection regarding early diastolic tricuspid and mitral annular motion velocities (P = 0.005 and P = 0.02, respectively). Conclusions: It seems that echocardiographic parameters, including TDI, might be adjunct to, rather than substitution for, EMB findings for early diagnosis of acute allograft rejection.","PeriodicalId":43653,"journal":{"name":"International Cardiovascular Research Journal","volume":"24 6 1","pages":"35-42"},"PeriodicalIF":0.2,"publicationDate":"2016-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68174794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
*Corresponding author: Yavuzer Koza, Ataturk University, Faculty of Medicine, Department of Cardiology, Erzurum, Turkey Tel: +90-4422318503, E-mail: yavuzerkoza@hotmail.com Percutaneous Coronary Intervention (PCI) has been an integral part of management of coronary artery disease over the past three decades. PCI reduces mortality in ST-segment Elevation Myocardial Infarction (STEMI) and improves cardiovascular outcomes in non-STEMI and unstable angina (1, 2). However, the role of PCI in management of stable coronary artery disease is still debatable (3). Although determined by interaction of a large number of factors, prognosis of patients with myocardial infarction is directly related to Left Ventricular (LV) function and size (4). In clinical practice, the right ventricle has remained a forgotten chamber behind the left ventricle. Likewise, most studies have evaluated the prognostic importance of LV function with little interest in the right ventricle. However, involvement of the right ventricle was significantly associated with increased mortality in patients with acute STEMI treated with primary PCI (5). The study by Nikdoust et al. (6) in a recent issue of the International Cardiovascular Research Journal highlights a significant improvement in Right Ventricular (RV) function, but not LV function, after Right Coronary Artery (RCA) PCI in patients with unstable angina. Echocardiographic measurements were performed in a total of 30 subjects prior to elective PCI. Two months after PCI, echocardiography was repeated and the results were compared to baseline. According to the findings, RV systolic and diastolic functional parameters were significantly improved, but there was no significant correlation between these parameters and LV function. Thus, the authors suggested that revascularization of the RCA might be beneficial for patients suffering from RV failure due to ischemia. The significant improvement in RV, but not LV, function, after right coronary PCI in a relatively small population is interesting. In agreement with this study, previous studies also reported significant improvements in RV function after PCI. However, these studies mainly included STEMI patients with different locations (5). In a study on 133 patients with inferior infarction without concomitant RV infarction who underwent primary PCI, only regional RV ►Implication for health policy/practice/research/medical education: To date, the impact of the percutaneous intervention on left ventricular function has been widely studied, with little interest in the right ventricle. This article highlights the importance of the interdependence of the right and left ventricles and the role of percutaneous coronary intervention in the right ventricular function with regard to different lesion sites after isolated right coronary angioplasty.
*通讯作者:Yavuzer Koza，土耳其阿塔图尔克大学医学院心脏病学系，埃尔祖鲁姆，Tel: +90-4422318503, E-mail: yavuzerkoza@hotmail.com在过去的三十年中，经皮冠状动脉介入治疗(PCI)已成为冠状动脉疾病治疗不可或缺的一部分。PCI降低st段抬高型心肌梗死(STEMI)的死亡率，改善非STEMI和不稳定型心绞痛的心血管结局(1,2)。然而，PCI在稳定型冠状动脉疾病治疗中的作用仍存在争议(3)。尽管由大量因素相互作用决定，但心肌梗死患者的预后与左心室(LV)功能和大小直接相关(4)。右心室一直是左心室后面的一个被遗忘的腔室。同样，大多数研究都评估了左室功能对预后的重要性，而对右心室的研究却很少。然而，急性STEMI患者行首次PCI治疗时，累及右心室与死亡率增加显著相关(5)。Nikdoust等人(6)在最近一期《国际心血管研究杂志》(International Cardiovascular Research Journal)上的研究强调，不稳定型心绞痛患者行右冠状动脉(RCA) PCI治疗后，右心室(RV)功能显著改善，但左室功能没有改善。在选择性PCI术前，共对30名受试者进行超声心动图测量。PCI术后2个月复查超声心动图并与基线比较。结果显示，左室收缩和舒张功能参数明显改善，但这些参数与左室功能无显著相关性。因此，作者认为RCA的血运重建可能对因缺血导致的右心室衰竭的患者有益。在相对较小的人群中，右冠状动脉PCI术后左室功能显著改善，而左室功能没有显著改善，这是有趣的。与本研究一致，先前的研究也报道了PCI术后RV功能的显著改善。然而，这些研究主要包括不同部位的STEMI患者(5)。在一项研究中，133例未合并左室梗死的下壁梗死患者接受了首次PCI治疗，只有局部左室►对卫生政策/实践/研究/医学教育的影响:迄今为止，经皮介入治疗对左室功能的影响已经被广泛研究，但对右心室的影响却很少。这篇文章强调了左右心室相互依赖的重要性，以及经皮冠状动脉介入治疗在孤立的右冠状动脉成形术后不同病变部位的右心室功能中的作用。
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