Pub Date : 2023-04-19DOI: 10.56543/aaeeu.2023.2.1.03
M. Prakashini
Inflammatory rheumatic disorders come with their plethora of complications including accelerated ovarian aging and the associated adversities which could be a consequence of disease itself or treatment with immunosuppressants. While aiming for treat-to-target in these patients, its effect on the ovaries takes a backseat. This review focusses on this underexplored avenue of effect of inflammation, inflamm-aging and the associated complications that come with early menopause, in the context of autoimmune rheumatic diseases (AIRDs). Some autoimmune diseases like lupus have a major role of estrogen in their causation and tend to be less severe when the onset is after menopause, while in other inflammatory arthritis like rheumatoid arthritis (RA), estrogen may have some anti-inflammatory potential. Inflamm-aging that is associated with the AIRDs also leads to early menopause and premature ovarian insufficiency in some patients, which adds-on to the morbidity and sometimes, mortality. With early ovarian aging and precipitous decline in circulating estrogen, there is accelerated reduction in the bone mass and early set-in of osteoporosis. Long-term steroids, on-going inflammation and RA itself are major risk factors. The high risk of detrimental fragility fractures in these patients with a consequential reduction in the quality of life with higher loss of disability adjusted life years (DALY) and poorer functional outcomes, contributes to long-term morbidity. While remission induction and maintenance are a major part of treatment, physicians should exercise a keen eye towards recognizing early menopause and its adversities and inculcate measures for osteo-protection and prevent adding on to the morbidity. Future prospects would include attempts at delaying ovarian aging by targeting mTOR/S6 kinase pathways and preservation of ovarian tissue.
{"title":"INFLAMMATION, MENOPAUSE, AND WOMEN’S HEALTH: A RHEUMATOLOGICAL PERSPECTIVE","authors":"M. Prakashini","doi":"10.56543/aaeeu.2023.2.1.03","DOIUrl":"https://doi.org/10.56543/aaeeu.2023.2.1.03","url":null,"abstract":"Inflammatory rheumatic disorders come with their plethora of complications including accelerated ovarian aging and the associated adversities which could be a consequence of disease itself or treatment with immunosuppressants. While aiming for treat-to-target in these patients, its effect on the ovaries takes a backseat. \u0000This review focusses on this underexplored avenue of effect of inflammation, inflamm-aging and the associated complications that come with early menopause, in the context of autoimmune rheumatic diseases (AIRDs). Some autoimmune diseases like lupus have a major role of estrogen in their causation and tend to be less severe when the onset is after menopause, while in other inflammatory arthritis like rheumatoid arthritis (RA), estrogen may have some anti-inflammatory potential. Inflamm-aging that is associated with the AIRDs also leads to early menopause and premature ovarian insufficiency in some patients, which adds-on to the morbidity and sometimes, mortality. \u0000With early ovarian aging and precipitous decline in circulating estrogen, there is accelerated reduction in the bone mass and early set-in of osteoporosis. Long-term steroids, on-going inflammation and RA itself are major risk factors. The high risk of detrimental fragility fractures in these patients with a consequential reduction in the quality of life with higher loss of disability adjusted life years (DALY) and poorer functional outcomes, contributes to long-term morbidity. While remission induction and maintenance are a major part of treatment, physicians should exercise a keen eye towards recognizing early menopause and its adversities and inculcate measures for osteo-protection and prevent adding on to the morbidity. Future prospects would include attempts at delaying ovarian aging by targeting mTOR/S6 kinase pathways and preservation of ovarian tissue.","PeriodicalId":437966,"journal":{"name":"Anti-Aging Eastern Europe","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133700483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-19DOI: 10.56543/aaeeu.2023.2.1.06
İ. Coşkun Benlidayı
Exercising is an essential component of healthy aging. The benefits of exercise are numerous. There are certain benefits on physical performance. Exercise in older adults can increase endurance, improve balance and quality of life. The benefits of exercise are not limited to physical health. Psychological variables such as depressive mood and anxiety can also be modified by regular exercise. There are several types of exercise regimens. The most common exercise types tailored to older adults include aerobic training, strengthening, flexibility exercises and balance exercises. Specific exercises can be directed to individuals with certain health disorders. Exercising may mediate psychological health through the hypothalamus-pituitary-adrenal axis. Improved sleep via exercise can further lead to an improvement in mood and cognition. The current article reviewed the recent literature regarding the effects of exercising on psychological well-being in older adults.
{"title":"THE EFFECTS OF EXERCISING ON PSYCHOLOGICAL WELL-BEING IN OLDER ADULTS","authors":"İ. Coşkun Benlidayı","doi":"10.56543/aaeeu.2023.2.1.06","DOIUrl":"https://doi.org/10.56543/aaeeu.2023.2.1.06","url":null,"abstract":"Exercising is an essential component of healthy aging. The benefits of exercise are numerous. There are certain benefits on physical performance. Exercise in older adults can increase endurance, improve balance and quality of life. The benefits of exercise are not limited to physical health. Psychological variables such as depressive mood and anxiety can also be modified by regular exercise. There are several types of exercise regimens. The most common exercise types tailored to older adults include aerobic training, strengthening, flexibility exercises and balance exercises. Specific exercises can be directed to individuals with certain health disorders. Exercising may mediate psychological health through the hypothalamus-pituitary-adrenal axis. Improved sleep via exercise can further lead to an improvement in mood and cognition. The current article reviewed the recent literature regarding the effects of exercising on psychological well-being in older adults.","PeriodicalId":437966,"journal":{"name":"Anti-Aging Eastern Europe","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121350510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-19DOI: 10.56543/aaeeu.2023.2.1.08
B. Koçyiğit
Spa therapy refers to the preventative, therapeutic, and rehabilitative use of thermo mineral waters, mud/peloid compresses, and natural gases. Applications are administered in sessions, and treatment regimens are determined in detail. Various modalities, such as exercise interventions, massage, phytotherapy, relaxation techniques, psychotherapy, nutrition, and electrotherapy, can be incorporated into the treatment process. Spa therapy has been effectively used to manage various diseases in many European countries, Japan, and Israel. Due to its natural structure, the difficulties in using drugs that frequently have side effects, and the limitations of many contemporary therapeutic alternatives, it is still a choice for treating a number of chronic conditions, especially rheumatic disorders. Furthermore, the global population is getting older. Considering the comorbidities, organ dysfunctions, and multiple drug use of elderly individuals, non-pharmacological treatment methods such as spa therapy have become more prominent. Spa therapy has been shown to be effective in treating osteoarthritis, balance problems, and chronic pain in older adults. Additionally, it might be chosen for managing psychiatric conditions and mood changes. Alterations in telomere lengths, reduced pain levels, increased cortisol concentrations, and an overall anti-inflammatory influence may mediate spa therapy’s anti-aging effect. Although opinions and assumptions support its anti-aging properties, more research is needed to prove its biological effects.
{"title":"SPA THERAPY: A GERIATRIC PERSPECTIVE","authors":"B. Koçyiğit","doi":"10.56543/aaeeu.2023.2.1.08","DOIUrl":"https://doi.org/10.56543/aaeeu.2023.2.1.08","url":null,"abstract":"Spa therapy refers to the preventative, therapeutic, and rehabilitative use of thermo mineral waters, mud/peloid compresses, and natural gases. Applications are administered in sessions, and treatment regimens are determined in detail. Various modalities, such as exercise interventions, massage, phytotherapy, relaxation techniques, psychotherapy, nutrition, and electrotherapy, can be incorporated into the treatment process. Spa therapy has been effectively used to manage various diseases in many European countries, Japan, and Israel. Due to its natural structure, the difficulties in using drugs that frequently have side effects, and the limitations of many contemporary therapeutic alternatives, it is still a choice for treating a number of chronic conditions, especially rheumatic disorders. Furthermore, the global population is getting older. Considering the comorbidities, organ dysfunctions, and multiple drug use of elderly individuals, non-pharmacological treatment methods such as spa therapy have become more prominent. Spa therapy has been shown to be effective in treating osteoarthritis, balance problems, and chronic pain in older adults. Additionally, it might be chosen for managing psychiatric conditions and mood changes. Alterations in telomere lengths, reduced pain levels, increased cortisol concentrations, and an overall anti-inflammatory influence may mediate spa therapy’s anti-aging effect. Although opinions and assumptions support its anti-aging properties, more research is needed to prove its biological effects.","PeriodicalId":437966,"journal":{"name":"Anti-Aging Eastern Europe","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122434698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-19DOI: 10.56543/aaeeu.2023.2.1.04
Emine Koçyiğit
Body image relates to how individuals perceive and feel about their bodies. Research on body image in men, women, and adolescents has increased substantially in the past two decades. Body image, determined by various instruments, is classified as either negative or positive. A positive body image implies that the body is seen accurately and that the individual is delighted with their physical appearance. Negative body images are characterized by inaccurate perceptions of all or a part of the body and uncomfortable feelings associated with them. Negative body image has been linked to eating disorders and mental disorders. The media, social pressures, cultural norms, age, gender, level of education, and an individual’s opinion of beauty all influence his or her body image perception. Studies in this area have been predominantly conducted with a focus on the association between eating disorders and dissatisfaction with body image in adolescents and young women. However, there is a growing interest in studying how body image functions and how it corresponds with psychological well-being across a lifetime in various demographic groups, especially among older adults. In this review, the life-altering body image satisfaction of men and women, as well as associated problems, were examined. The relationship between body dissatisfaction across ages, confounded by obesity, eating disorders, low physical activity, age-related reduction in sexual activity, and unhealthy lifestyle behaviors has been investigated.
{"title":"BODY IMAGE IN AGING","authors":"Emine Koçyiğit","doi":"10.56543/aaeeu.2023.2.1.04","DOIUrl":"https://doi.org/10.56543/aaeeu.2023.2.1.04","url":null,"abstract":"Body image relates to how individuals perceive and feel about their bodies. Research on body image in men, women, and adolescents has increased substantially in the past two decades. Body image, determined by various instruments, is classified as either negative or positive. A positive body image implies that the body is seen accurately and that the individual is delighted with their physical appearance. Negative body images are characterized by inaccurate perceptions of all or a part of the body and uncomfortable feelings associated with them. Negative body image has been linked to eating disorders and mental disorders. The media, social pressures, cultural norms, age, gender, level of education, and an individual’s opinion of beauty all influence his or her body image perception. Studies in this area have been predominantly conducted with a focus on the association between eating disorders and dissatisfaction with body image in adolescents and young women. However, there is a growing interest in studying how body image functions and how it corresponds with psychological well-being across a lifetime in various demographic groups, especially among older adults. In this review, the life-altering body image satisfaction of men and women, as well as associated problems, were examined. The relationship between body dissatisfaction across ages, confounded by obesity, eating disorders, low physical activity, age-related reduction in sexual activity, and unhealthy lifestyle behaviors has been investigated.","PeriodicalId":437966,"journal":{"name":"Anti-Aging Eastern Europe","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129269814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-19DOI: 10.56543/aaeeu.2023.2.1.02
Y. Fedorchenko
As COVID-19 morbidity rates continue to increase tremendously across the world, it has a profound effect on female health. The available data suggest that men demonstrate greater disease severity and/or mortality than women in the middle-aged group, however, these differences seem not to be preserved in the elderly patients. Clinicians should consider gender disparities in diagnostic and therapeutic management. The severity of COVID-19 viral infection is tightly linked with cytokine balance which is inevitably influenced by hormonal changes. Lack of estrogens during the ageing process in women poses a significant threat during the acute phase as well as in the sequel, which may result in autoimmunity or long-term complications. Research on female ageing amid the COVID-19 pandemic is urgently needed to alleviate immune dysfunction in these patients, define best practices, and develop health promotion strategies.
{"title":"FEMALE HEALTH AMIDST THE COVID-19 PANDEMIC","authors":"Y. Fedorchenko","doi":"10.56543/aaeeu.2023.2.1.02","DOIUrl":"https://doi.org/10.56543/aaeeu.2023.2.1.02","url":null,"abstract":"As COVID-19 morbidity rates continue to increase tremendously across the world, it has a profound effect on female health. \u0000The available data suggest that men demonstrate greater disease severity and/or mortality than women in the middle-aged group, however, these differences seem not to be preserved in the elderly patients. \u0000Clinicians should consider gender disparities in diagnostic and therapeutic management. The severity of COVID-19 viral infection is tightly linked with cytokine balance which is inevitably influenced by hormonal changes. Lack of estrogens during the ageing process in women poses a significant threat during the acute phase as well as in the sequel, which may result in autoimmunity or long-term complications. Research on female ageing amid the COVID-19 pandemic is urgently needed to alleviate immune dysfunction in these patients, define best practices, and develop health promotion strategies.","PeriodicalId":437966,"journal":{"name":"Anti-Aging Eastern Europe","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114884892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-19DOI: 10.56543/aaeeu.2023.2.1.01
Oleksii Bashkirtsev, O. Zimba, A. Gasparyan
Psychological interventions may improve patients’ motivation and adherence to various therapies, including those alleviating pain, depression, and fatigue. Evaluating patients’ psychological status and choosing the most appropriate intervention may improve combined treatment outcomes, particularly in the elderly and other vulnerable groups. Exposure to psychotraumatic events such as violence, torture, and limb amputation should be appropriately assessed to choose a psychotherapy method. Narrative exposure therapy and cognitive behavioural therapy are commonly used psychological interventions with variable level of evidence. Training first-contact health professionals and psychologists to use the most efficient evidence-based psychological interventions is thus becoming critical at the current stage.
{"title":"PSYCHOLOGICAL INTERVENTIONS IN THE TIME OF CRISIS","authors":"Oleksii Bashkirtsev, O. Zimba, A. Gasparyan","doi":"10.56543/aaeeu.2023.2.1.01","DOIUrl":"https://doi.org/10.56543/aaeeu.2023.2.1.01","url":null,"abstract":"Psychological interventions may improve patients’ motivation and adherence to various therapies, including those alleviating pain, depression, and fatigue. Evaluating patients’ psychological status and choosing the most appropriate intervention may improve combined treatment outcomes, particularly in the elderly and other vulnerable groups. Exposure to psychotraumatic events such as violence, torture, and limb amputation should be appropriately assessed to choose a psychotherapy method. Narrative exposure therapy and cognitive behavioural therapy are commonly used psychological interventions with variable level of evidence. Training first-contact health professionals and psychologists to use the most efficient evidence-based psychological interventions is thus becoming critical at the current stage.","PeriodicalId":437966,"journal":{"name":"Anti-Aging Eastern Europe","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116014305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-19DOI: 10.56543/aaeeu.2023.2.1.12
I. Benlidayı
GET PHYSICALLY AND PSYCHOLOGICALLY HEALTHIER BY EXERCISING!
通过锻炼让身体和心理更健康!
{"title":"GET PHYSICALLY AND PSYCHOLOGICALLY HEALTHIER BY EXERCISING!","authors":"I. Benlidayı","doi":"10.56543/aaeeu.2023.2.1.12","DOIUrl":"https://doi.org/10.56543/aaeeu.2023.2.1.12","url":null,"abstract":"GET PHYSICALLY AND PSYCHOLOGICALLY HEALTHIER BY EXERCISING!","PeriodicalId":437966,"journal":{"name":"Anti-Aging Eastern Europe","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129853913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-19DOI: 10.56543/aaeeu.2023.2.1.09
S. Aykan, G. Akyuz
Hip fracture is one of the most common fractures among the elderly population with high rates of mortality and morbidity. The annual incidence of hip fractures is predicted to be increased by around 16 times by the year 2050. Due to the high cost of traditional rehabilitation after hip fracture surgery and the effect of pandemics, telerehabilitation after hip fracture is gaining more importance in recent years. This review is designed to examine the importance and progress of telerehabilitation after hip fracture surgery. PubMed/MEDLINE, Scopus, and Web of Science for English-language sources were searched from their inception using the keywords telerehabilitation and hip fracture between January 2014 and January 2023. The literature search resulted in 29 non-duplicate records and 8 of them were eligible and were included in this review. Telerehabilitation is a feasible, safe, and effective rehabilitation method after hip fracture surgery. However, the ability of elderly patients and their caregivers to use technology and apply what they see seems to be a big disadvantage. The literature lacks long-term studies with larger patient groups.
髋部骨折是老年人最常见的骨折之一，具有较高的死亡率和发病率。预计到2050年，髋部骨折的年发病率将增加约16倍。近年来，由于传统的髋部骨折术后康复费用高，以及流行病的影响，髋部骨折后远程康复越来越受到重视。本综述旨在探讨髋部骨折术后远程康复的重要性和进展。在2014年1月至2023年1月期间，使用远程康复和髋部骨折的关键词对PubMed/MEDLINE、Scopus和Web of Science的英文来源进行检索。文献检索得到29条无重复记录，其中8条符合条件，纳入本综述。远程康复是髋部骨折术后一种可行、安全、有效的康复方法。然而，老年患者和他们的护理人员使用技术和应用他们所看到的东西的能力似乎是一个很大的劣势。文献缺乏对更大患者群体的长期研究。
{"title":"TELEREHABILITATION AFTER HIP-FRACTURE SURGERY","authors":"S. Aykan, G. Akyuz","doi":"10.56543/aaeeu.2023.2.1.09","DOIUrl":"https://doi.org/10.56543/aaeeu.2023.2.1.09","url":null,"abstract":"Hip fracture is one of the most common fractures among the elderly population with high rates of mortality and morbidity. The annual incidence of hip fractures is predicted to be increased by around 16 times by the year 2050. Due to the high cost of traditional rehabilitation after hip fracture surgery and the effect of pandemics, telerehabilitation after hip fracture is gaining more importance in recent years. This review is designed to examine the importance and progress of telerehabilitation after hip fracture surgery. PubMed/MEDLINE, Scopus, and Web of Science for English-language sources were searched from their inception using the keywords telerehabilitation and hip fracture between January 2014 and January 2023. The literature search resulted in 29 non-duplicate records and 8 of them were eligible and were included in this review. Telerehabilitation is a feasible, safe, and effective rehabilitation method after hip fracture surgery. However, the ability of elderly patients and their caregivers to use technology and apply what they see seems to be a big disadvantage. The literature lacks long-term studies with larger patient groups.","PeriodicalId":437966,"journal":{"name":"Anti-Aging Eastern Europe","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125330757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-19DOI: 10.56543/aaeeu.2023.2.1.05
Dimitrina Miteva, T. Velikova
Immunosenescence or aging of the immune system is characterized by dysregulation of the innate and adaptive immune system mechanisms, associated with a systemic low-grade inflammation (i.e., «inflammaging»), non-effective protective humoral and cellular immune responses to a microorgamis or vaccine, autoimmunity, and cancer. In addition, genetic dysregulation and alterations across the immune system drive the cellular manifestations of immunosenescence. In this narrative review, we provide an overview of the recent advancements in immunosenescence research concerning epigenetics alterations in gene regulation and disturbances in gene expression in the aging immune system, focusing on DNA methylation, histone modifications, and microRNAs.
{"title":"EPIGENETIC ALTERATIONS IN GENE EXPRESSION IN THE AGING IMMUNE SYSTEM","authors":"Dimitrina Miteva, T. Velikova","doi":"10.56543/aaeeu.2023.2.1.05","DOIUrl":"https://doi.org/10.56543/aaeeu.2023.2.1.05","url":null,"abstract":"Immunosenescence or aging of the immune system is characterized by dysregulation of the innate and adaptive immune system mechanisms, associated with a systemic low-grade inflammation (i.e., «inflammaging»), non-effective protective humoral and cellular immune responses to a microorgamis or vaccine, autoimmunity, and cancer. In addition, genetic dysregulation and alterations across the immune system drive the cellular manifestations of immunosenescence. In this narrative review, we provide an overview of the recent advancements in immunosenescence research concerning epigenetics alterations in gene regulation and disturbances in gene expression in the aging immune system, focusing on DNA methylation, histone modifications, and microRNAs.","PeriodicalId":437966,"journal":{"name":"Anti-Aging Eastern Europe","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123556409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-28DOI: 10.56543/aaeeu.2022.1.2.06
Burhan Fatih Koçyiğit
Infertility is the inability to conceive after one year of unprotected intercourse, and about one in six couples deal with this issue. Nearly half of the factors contributing to a couple’s infertility are female-related, and the underlying cause is variable. Many treatment options can be used depending on the underlying cause of infertility. The available treatments often include in vitro fertilization, intrauterine insemination, and fertility-inducing drugs. Numerous couples favor complementary medicine alongside conventional treatments to enhance treatment efficacy and reduce side effects. Manual therapy and massage are among these complementary treatment approaches. Manual therapy is defined in various ways. One of them is manipulating and mobilizing soft tissue structures and related joints using the hands. Manual therapy can alleviate pain, reduce inflammation, prevent contracture formation, manage existing contractures, increase range of motion, aid mobilization, and improve overall health. It contains a variety of massage treatments, stretching, and mobilization applications. Manual therapy and massage can be administered to manage various disorders, from pediatric to geriatric populations. These are safe interventions. Manual therapy and massage have beneficial effects on the management of female infertility. These methods reduce adhesions and mobilize organs in the pelvic region. They have positive effects on circulatory system disorders, including lymphatic drainage abnormalities. Overcoming reproductive system lymphatic drainage and circulation difficulties can result in balanced hormone levels, regular menstrual cycles, and pregnancies. In addition, manual therapy and massage improve the psychological state of individuals in a way that will benefit the management of female infertility.
{"title":"CAN MANUAL THERAPY AND MASSAGE BE USED AS COMPLEMENTARY METHODS FOR FEMALE INFERTILITY IN DIFFERENT AGE GROUPS?","authors":"Burhan Fatih Koçyiğit","doi":"10.56543/aaeeu.2022.1.2.06","DOIUrl":"https://doi.org/10.56543/aaeeu.2022.1.2.06","url":null,"abstract":"Infertility is the inability to conceive after one year of unprotected intercourse, and about one in six couples deal with this issue. Nearly half of the factors contributing to a couple’s infertility are female-related, and the underlying cause is variable. Many treatment options can be used depending on the underlying cause of infertility. The available treatments often include in vitro fertilization, intrauterine insemination, and fertility-inducing drugs. Numerous couples favor complementary medicine alongside conventional treatments to enhance treatment efficacy and reduce side effects. Manual therapy and massage are among these complementary treatment approaches. Manual therapy is defined in various ways. One of them is manipulating and mobilizing soft tissue structures and related joints using the hands. Manual therapy can alleviate pain, reduce inflammation, prevent contracture formation, manage existing contractures, increase range of motion, aid mobilization, and improve overall health. It contains a variety of massage treatments, stretching, and mobilization applications. Manual therapy and massage can be administered to manage various disorders, from pediatric to geriatric populations. These are safe interventions. Manual therapy and massage have beneficial effects on the management of female infertility. These methods reduce adhesions and mobilize organs in the pelvic region. They have positive effects on circulatory system disorders, including lymphatic drainage abnormalities. Overcoming reproductive system lymphatic drainage and circulation difficulties can result in balanced hormone levels, regular menstrual cycles, and pregnancies. In addition, manual therapy and massage improve the psychological state of individuals in a way that will benefit the management of female infertility.","PeriodicalId":437966,"journal":{"name":"Anti-Aging Eastern Europe","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116833552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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