1 Sule Ozel1, Yaprak Engin-Ustun1, Rifat Taner Aksoy1, Hatice Kansu-Celik1, Rabia Nazik Yuksel2, Bugra Coskun1, Salim Erkaya1 1Obstetrics and Gynecology, Zekai Tahir Burak Woman’s Health, Education and Research Hospital, 2Psychiatry Department, Ankara Numune Education and Research Hospital, Ankara, Turkey. The effect of abortion on anxiety The effect of induced legal abortions on anxiety levels before and after the procedure
{"title":"The effect of induced legal abortions on anxiety levels before and after the procedure","authors":"Sule Ozel","doi":"10.4328/JCAM.5800","DOIUrl":"https://doi.org/10.4328/JCAM.5800","url":null,"abstract":"1 Sule Ozel1, Yaprak Engin-Ustun1, Rifat Taner Aksoy1, Hatice Kansu-Celik1, Rabia Nazik Yuksel2, Bugra Coskun1, Salim Erkaya1 1Obstetrics and Gynecology, Zekai Tahir Burak Woman’s Health, Education and Research Hospital, 2Psychiatry Department, Ankara Numune Education and Research Hospital, Ankara, Turkey. The effect of abortion on anxiety The effect of induced legal abortions on anxiety levels before and after the procedure","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49526860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DOI: 10.4328/JCAM.6002 Received: 11.08.2018 Accepted: 12.09.2018 Published Online: 17.09.2018 Printed: 01.01.2019 J Clin Anal Med 2019;10(1): 113-6 Corresponding Author: Neslihan Kurtul, Department of Radiation Oncology, Sutcu Imam University Faculty of Medicine, Avsar Campus, Kahramanmaras, Turkey. GSM: +905067872841 E-Mail: drneslihankurtul@gmail.com ORCID ID: 0000-0001-9173-6280 Abstract Aim: In this study, we aimed to investigate the optic coherence tomography findings in patients who received external beam radiotherapy. Material and Method: All consecutive subjects applied to the radiation oncology department due to head, neck or brain tumors were enrolled prospectively into the study. Macula radiation dose and eye dose were calculated from dose-volume histogram plot curve. Eyes were evaluated with regard to macular thickness with optical coherence tomography at the baseline and 6th month after the radiotherapy. Results: A total of 32 eyes of 16 patients were included in the study. The mean macula dose was 1780 ± 1403 cGy, maximum macula dose was 2059 ± 1479 cGy and the mean eye dose was 1015 ± 784 cGy. Among 16 patients, macular edema was developed in one patient (%6,25) 18 weeks after the radiotherapy. Apart from this patient, no other patient developed any kind of retinal complication regarding the radiotherapy during 6 months follow up. The retina showed no change with regard to the studied parameters during the study period (p<0.05). Discussion: OCT is an effective way to determine early changes in patients undergoing radiotherapy and it enables prompt diagnosis of early clinical macular edema. This study is of significance in that our patients didn’t get direct retinal radiation therapy during 6-months follow-up. Long-term studies with a larger cohort group will yield more suggestive data on this clinical entity.
{"title":"Optic coherence tomography evaluation of macula after external beam radiotherapy","authors":"Neslihan Kurtul","doi":"10.4328/JCAM.6002","DOIUrl":"https://doi.org/10.4328/JCAM.6002","url":null,"abstract":"DOI: 10.4328/JCAM.6002 Received: 11.08.2018 Accepted: 12.09.2018 Published Online: 17.09.2018 Printed: 01.01.2019 J Clin Anal Med 2019;10(1): 113-6 Corresponding Author: Neslihan Kurtul, Department of Radiation Oncology, Sutcu Imam University Faculty of Medicine, Avsar Campus, Kahramanmaras, Turkey. GSM: +905067872841 E-Mail: drneslihankurtul@gmail.com ORCID ID: 0000-0001-9173-6280 Abstract Aim: In this study, we aimed to investigate the optic coherence tomography findings in patients who received external beam radiotherapy. Material and Method: All consecutive subjects applied to the radiation oncology department due to head, neck or brain tumors were enrolled prospectively into the study. Macula radiation dose and eye dose were calculated from dose-volume histogram plot curve. Eyes were evaluated with regard to macular thickness with optical coherence tomography at the baseline and 6th month after the radiotherapy. Results: A total of 32 eyes of 16 patients were included in the study. The mean macula dose was 1780 ± 1403 cGy, maximum macula dose was 2059 ± 1479 cGy and the mean eye dose was 1015 ± 784 cGy. Among 16 patients, macular edema was developed in one patient (%6,25) 18 weeks after the radiotherapy. Apart from this patient, no other patient developed any kind of retinal complication regarding the radiotherapy during 6 months follow up. The retina showed no change with regard to the studied parameters during the study period (p<0.05). Discussion: OCT is an effective way to determine early changes in patients undergoing radiotherapy and it enables prompt diagnosis of early clinical macular edema. This study is of significance in that our patients didn’t get direct retinal radiation therapy during 6-months follow-up. Long-term studies with a larger cohort group will yield more suggestive data on this clinical entity.","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41588421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of the use of conventional versus computer-aided design/computer-aided manufacturing sockets on clinical characteristics and quality of life of transfemoral amputees","authors":"A. Aydın","doi":"10.4328/jcam.5845","DOIUrl":"https://doi.org/10.4328/jcam.5845","url":null,"abstract":"","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41607283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Yıldırım, Hande Küçük Kurtulgan, H. Kilicgun, D. Bakir, Sepil Ersan
1 Malik Ejder Yıldırım1, Hande Küçük Kurtulgan1, Hasan Kılıçgün2, Deniz Bakır3, Sepil Erşan3 1 Department of Medical Genetics, Faculty of Medicine, Cumhuriyet University, Sivas, 2Deparment of Nutrition and Dietetics, Faculty of Health Sciences, Erzincan University, Erzincan, 3 Department of Biochemistry, Faculty of Medicine, Cumhuriyet University, Sivas, Turkey TIMP-1 and TSP-1 with familial mediterranean fever A possible interaction of TIMP-1 and TSP-1 with familial mediterranean fever
1 Malik Ejder Yıldırım1, Hande k库尔图尔甘1,Hasan Kılıçgün2, Deniz Bakır3, Sepil er 1 1捷克共和国大学医学院医学遗传学系,2捷克共和国埃尔津詹大学健康科学学院营养与饮食学系,3土耳其共和国锡瓦斯共和国共和国医学院生物化学系TIMP-1和TSP-1与家族性地中海热TIMP-1和TSP-1可能与家族性地中海热相互作用
{"title":"A possible interaction of TIMP-1 and TSP-1 with familial mediterranean fever","authors":"M. Yıldırım, Hande Küçük Kurtulgan, H. Kilicgun, D. Bakir, Sepil Ersan","doi":"10.4328/JCAM.5959","DOIUrl":"https://doi.org/10.4328/JCAM.5959","url":null,"abstract":"1 Malik Ejder Yıldırım1, Hande Küçük Kurtulgan1, Hasan Kılıçgün2, Deniz Bakır3, Sepil Erşan3 1 Department of Medical Genetics, Faculty of Medicine, Cumhuriyet University, Sivas, 2Deparment of Nutrition and Dietetics, Faculty of Health Sciences, Erzincan University, Erzincan, 3 Department of Biochemistry, Faculty of Medicine, Cumhuriyet University, Sivas, Turkey TIMP-1 and TSP-1 with familial mediterranean fever A possible interaction of TIMP-1 and TSP-1 with familial mediterranean fever","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70550186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Use of multiple artery grafts to ensure long-term graft patency in coronary bypass surgeries","authors":"K. A. Kara","doi":"10.4328/JCAM.6001","DOIUrl":"https://doi.org/10.4328/JCAM.6001","url":null,"abstract":"","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48698954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Should we use remifentanil in every dose and every case?","authors":"Naldan Muhammet Emin","doi":"10.4328/JCAM.5942","DOIUrl":"https://doi.org/10.4328/JCAM.5942","url":null,"abstract":"","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43760079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DOI: 10.4328/JCAM.6003 Received: 13.08.2018 Accepted: 28.08.2018 Published Online: 04.09.2018 Printed: 01.01.2019 J Clin Anal Med 2019;10(1): 35-40 Corresponding Author: Fatma Ceyla Eraldemir, Department of Biochemistry, Kocaeli University Facultyof Medicine, Kocaeli, Turkey. T.: +9
{"title":"Evaluation of analytical quality of cardiac biomarkers in the emergency laboratory by sigma metrics","authors":"F. Eraldemir","doi":"10.4328/JCAM.6003","DOIUrl":"https://doi.org/10.4328/JCAM.6003","url":null,"abstract":"DOI: 10.4328/JCAM.6003 Received: 13.08.2018 Accepted: 28.08.2018 Published Online: 04.09.2018 Printed: 01.01.2019 J Clin Anal Med 2019;10(1): 35-40 Corresponding Author: Fatma Ceyla Eraldemir, Department of Biochemistry, Kocaeli University Facultyof Medicine, Kocaeli, Turkey. T.: +9","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44327150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DOI: 10.4328/JCAM.5980 Received: 09.08.2018 Accepted: 22.09.2018 Published Online: 25.09.2018 Printed: 01.01.2019 J Clin Anal Med 2019;10(1): 109-12 Corresponding Author: Erol Kiliç, Departman of General Surgery, Tayfur Sökmen Medicine Faculty, Mustafa Kemal Universty, 31000, Hatay, Turkey. GSM: +905324067941 E-Mail: ekkilic55@gmail.com ORCID ID: 0000-0002-0229-2911 Abstract Aim: Inflammation is the predominant factor in the development of gastrointestinal dysmotility or postoperative ileus although dissection and neurological and inflammatory factors secondary to intestinal manipulation have been blamed. In this study, we investigated the effectivity of local bupivacaine infusion for prevention of postoperative ileus. Material and Method: This retrospective study included patients that underwent median laparotomy and received conventional analgesia alone or conventional analgesia followed by local bupivacaine. Patients that received conventional analgesia (nonsteroidal anti-inflammatory drugs [NSAIDs] + opioids) followed by local bupivacaine infusion (15 mg/h during 48h) with Pain buster pump system were classified as Group 1 (n=30) and the patients that received conventional analgesia alone ( [NSAIDs] + opioids) were classified as Group 2 (n=31). Results: The groups were similar in terms of age, gender, preoperative ASA score, surgical technique, and operative time. The Visual Analog Scale (VAS) scores during the periods 8-24 and 24-48 h and the analgesic requirement during the periods 0-8, 8-24, and 24-48 h were significantly decreased in Group 1 compared to Group 2 (p<0.05). In Group 1, active postoperative bowel sounds started earlier (38 vs. 47 h) and mean time to first flatus/defecation was significantly lower than in Group 2 (64.13 ± 9.06 vs. 77.90 ± 10.25 h) (p<0.05). Discussion: Transfascial bupivacaine infusion appears to be an effective technique since it reduced early postoperative pain and postoperative analgesic requirement and also provided favorable effects in the prevention of postoperative ileus, thereby leading to shorter intensive care unit stay.
DOI: 10.4328 / JCAM.5980收稿日期:09.08.2018收稿日期:22.09.2018出版日期:25.09.2018印刷日期:01.01.2019 J clinical Anal Med 2019;10(1): 109-12通讯作者:Erol Kiliç, Tayfur普通外科学系Sökmen穆斯塔法·凯末尔大学医学院,31000,Hatay,土耳其。摘要目的:炎症是胃肠道运动障碍或术后肠梗阻发生的主要因素,尽管解剖和继发于肠道操作的神经和炎症因素已被归咎于此。在这项研究中,我们探讨了局部布比卡因输注预防术后肠梗阻的有效性。材料和方法:本回顾性研究包括行剖腹切开术并单独使用常规镇痛或常规镇痛后局部使用布比卡因的患者。采用常规镇痛(非甾体类抗炎药[NSAIDs] +阿片类药物)后加镇痛剂泵系统局部输注布比卡因(48小时15 mg/h)的患者为1组(n=30),单纯采用常规镇痛([NSAIDs] +阿片类药物)的患者为2组(n=31)。结果:两组患者在年龄、性别、术前ASA评分、手术技术、手术时间等方面无明显差异。1组大鼠8 ~ 24、24 ~ 48 h的视觉模拟评分及0 ~ 8、8 ~ 24、24 ~ 48 h的镇痛需求均显著低于2组(p<0.05)。组1术后主动肠音出现较早(38 h vs. 47 h),平均首次放屁/排便时间显著低于组2(64.13±9.06 h vs. 77.90±10.25 h) (p<0.05)。讨论:经筋膜布比卡因输注似乎是一种有效的技术,因为它减少了术后早期疼痛和术后镇痛需求,并且在预防术后肠梗阻方面也有良好的效果,从而缩短了重症监护病房的住院时间。
{"title":"Effectivity of local bupivacaine infusion in the prevention of postoperative ileus","authors":"E. Kılıç","doi":"10.4328/jcam.5980","DOIUrl":"https://doi.org/10.4328/jcam.5980","url":null,"abstract":"DOI: 10.4328/JCAM.5980 Received: 09.08.2018 Accepted: 22.09.2018 Published Online: 25.09.2018 Printed: 01.01.2019 J Clin Anal Med 2019;10(1): 109-12 Corresponding Author: Erol Kiliç, Departman of General Surgery, Tayfur Sökmen Medicine Faculty, Mustafa Kemal Universty, 31000, Hatay, Turkey. GSM: +905324067941 E-Mail: ekkilic55@gmail.com ORCID ID: 0000-0002-0229-2911 Abstract Aim: Inflammation is the predominant factor in the development of gastrointestinal dysmotility or postoperative ileus although dissection and neurological and inflammatory factors secondary to intestinal manipulation have been blamed. In this study, we investigated the effectivity of local bupivacaine infusion for prevention of postoperative ileus. Material and Method: This retrospective study included patients that underwent median laparotomy and received conventional analgesia alone or conventional analgesia followed by local bupivacaine. Patients that received conventional analgesia (nonsteroidal anti-inflammatory drugs [NSAIDs] + opioids) followed by local bupivacaine infusion (15 mg/h during 48h) with Pain buster pump system were classified as Group 1 (n=30) and the patients that received conventional analgesia alone ( [NSAIDs] + opioids) were classified as Group 2 (n=31). Results: The groups were similar in terms of age, gender, preoperative ASA score, surgical technique, and operative time. The Visual Analog Scale (VAS) scores during the periods 8-24 and 24-48 h and the analgesic requirement during the periods 0-8, 8-24, and 24-48 h were significantly decreased in Group 1 compared to Group 2 (p<0.05). In Group 1, active postoperative bowel sounds started earlier (38 vs. 47 h) and mean time to first flatus/defecation was significantly lower than in Group 2 (64.13 ± 9.06 vs. 77.90 ± 10.25 h) (p<0.05). Discussion: Transfascial bupivacaine infusion appears to be an effective technique since it reduced early postoperative pain and postoperative analgesic requirement and also provided favorable effects in the prevention of postoperative ileus, thereby leading to shorter intensive care unit stay.","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42442004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Information about bottom of iceberg of ammonia measurements in human plasma: Evaluation of uncertainty","authors":"F. Eraldemir","doi":"10.4328/jcam.5949","DOIUrl":"https://doi.org/10.4328/jcam.5949","url":null,"abstract":"DOI: 10.4328/JCAM.5949 Received: 26.06.2018 Accepted: 10.07.2018 Published Online: 11.07.2018 Printed: 01.01.2019 J Clin Anal Med 2019;10(1): 93-8 Corresponding Author: Fatma Ceyla Eraldemir, Department of Biochemistry, Kocaeli University, Kocaeli, Turkey. T.: +9","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70549988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DOI: 10.4328/JCAM.5956 Received: 28.06.2018 Accepted: 28.07.2018 Published Online: 29.07.2018 Printed: 01.01.2019 J Clin Anal Med 2019;10(1): 99-103 Corresponding Author: Özlem Özgür Gündeşlioğlu, Deparment of Pediatric Division of Pediatric Infectious Diseases, Faculty of Medicine, Cukurova University, Adana, Turkey. GSM: +905055677801 E-Mail:ozlemozgur1978@yahoo.com ORCID ID: 0000-0003-2202-7645 Abstract Aim: Brucellosis a worldwide infectious zoonotic disease. This study was aimed to evaluate the clinical, demographic characteristics, complications, treatment and follow-up results of pediatric patients diagnosed with brucellosis. Material and Method: The medical records of 148 pediatric patients who were diagnosed with brucellosis were studied retrospectively. Results: Sixty-one female (41.2%), 87 male (58.8%), in total 148 pediatric patients who were diagnosed with brucellosis were included in the study. Among the patients, 64.1% had a history of consuming fresh cheese, 4.1% had a history of consuming raw milk and 16.9% had a history of keeping a Brucella diagnosed animal at home. Brucella history rate in the family members of the patients was determined as 39.2%; and 12.8% of the patients included in the study were asymptomatic. The most common complaint of the patients who were symptomatic was fever (59.5%) followed by arthralgias (41.2%) and leg pain (38.5%). All patients were subjected to standard tube agglutination test and blood culture was taken from 93 patients. B. melitensis in blood culture was positive in 72% of the patients. Osteoarticular involvement developed in 12.1% of the patients; and 1.3% of the patients developed relapses after the end of the treatment. Discussion: Brucellosis is still an endemic disease in Turkey. Brucella can infect all organs and tissues and is a major cause of morbidity. The use of more than one antibiotic in the treatment and long treatment duration reduces patient compliance; thus, close follow-up of the patients is important.
{"title":"Brucella infection in children: Evaluation of 148 pediatric patients","authors":"Ö. Gündeşlioğlu","doi":"10.4328/JCAM.5956","DOIUrl":"https://doi.org/10.4328/JCAM.5956","url":null,"abstract":"DOI: 10.4328/JCAM.5956 Received: 28.06.2018 Accepted: 28.07.2018 Published Online: 29.07.2018 Printed: 01.01.2019 J Clin Anal Med 2019;10(1): 99-103 Corresponding Author: Özlem Özgür Gündeşlioğlu, Deparment of Pediatric Division of Pediatric Infectious Diseases, Faculty of Medicine, Cukurova University, Adana, Turkey. GSM: +905055677801 E-Mail:ozlemozgur1978@yahoo.com ORCID ID: 0000-0003-2202-7645 Abstract Aim: Brucellosis a worldwide infectious zoonotic disease. This study was aimed to evaluate the clinical, demographic characteristics, complications, treatment and follow-up results of pediatric patients diagnosed with brucellosis. Material and Method: The medical records of 148 pediatric patients who were diagnosed with brucellosis were studied retrospectively. Results: Sixty-one female (41.2%), 87 male (58.8%), in total 148 pediatric patients who were diagnosed with brucellosis were included in the study. Among the patients, 64.1% had a history of consuming fresh cheese, 4.1% had a history of consuming raw milk and 16.9% had a history of keeping a Brucella diagnosed animal at home. Brucella history rate in the family members of the patients was determined as 39.2%; and 12.8% of the patients included in the study were asymptomatic. The most common complaint of the patients who were symptomatic was fever (59.5%) followed by arthralgias (41.2%) and leg pain (38.5%). All patients were subjected to standard tube agglutination test and blood culture was taken from 93 patients. B. melitensis in blood culture was positive in 72% of the patients. Osteoarticular involvement developed in 12.1% of the patients; and 1.3% of the patients developed relapses after the end of the treatment. Discussion: Brucellosis is still an endemic disease in Turkey. Brucella can infect all organs and tissues and is a major cause of morbidity. The use of more than one antibiotic in the treatment and long treatment duration reduces patient compliance; thus, close follow-up of the patients is important.","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45961503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}