DOI: 10.4328/JCAM.5870 Received: 11.04.2018 Accepted: 05.05.2018 Published Online: 08.05.2018 Printed: 01.03.2019 J Clin Anal Med 2019;10(2): 173-6 Corresponding Author: Soner Sertan Kara, Department of Pediatric Infectious Diseases, Erzurum Regional Training and Research Hospital, Palandoken, Erzurum, 25280, Turkey. T.: +90 4422325449 GSM: +905352577885 F.: +90 4422325025 E-Mail: drsoner@yahoo.com ORCID ID: 0000-0002-8129-6063 Abstract Aim: Brucellosis involves almost all organs, although the endocrine organs are more protected. Impairment of lipid metabolism is also a little-known problem. We aimed to investigate hormone levels and lipid metabolism in children with acute brucellosis. Material and Method: Forty-six children with acute brucellosis, who had never been treated for the disease, and 39 healthy children were prospectively investigated. They were compared in terms of liver functions, serum lipid profiles, and hormone levels. Results: The patients had higher levels of AST, ALT, and GGT (p=0.04, p=0.01, and p=0.01, respectively). The patients also had higher cholesterol and triglyceride, and lower LDL and HDL levels than healthy children. The difference between triglyceride levels was statistically significant (p=0.04). Serum hormone levels were similar between groups. With antibiotic treatment and lifestyle modifications, all abnormal laboratory parameters returned to normal. Discussion: Children with acute brucellosis should be monitored for dyslipidemia, which can be relieved with antibiotics and lifestyle changes without using lipid lowering agents. Investigation of hormone levels in these patients is necessary only if signs and symptoms suggest an endocrine abnormality.
{"title":"Transient dyslipidemia in childhood brucellosis","authors":"S. Kara","doi":"10.4328/jcam.5870","DOIUrl":"https://doi.org/10.4328/jcam.5870","url":null,"abstract":"DOI: 10.4328/JCAM.5870 Received: 11.04.2018 Accepted: 05.05.2018 Published Online: 08.05.2018 Printed: 01.03.2019 J Clin Anal Med 2019;10(2): 173-6 Corresponding Author: Soner Sertan Kara, Department of Pediatric Infectious Diseases, Erzurum Regional Training and Research Hospital, Palandoken, Erzurum, 25280, Turkey. T.: +90 4422325449 GSM: +905352577885 F.: +90 4422325025 E-Mail: drsoner@yahoo.com ORCID ID: 0000-0002-8129-6063 Abstract Aim: Brucellosis involves almost all organs, although the endocrine organs are more protected. Impairment of lipid metabolism is also a little-known problem. We aimed to investigate hormone levels and lipid metabolism in children with acute brucellosis. Material and Method: Forty-six children with acute brucellosis, who had never been treated for the disease, and 39 healthy children were prospectively investigated. They were compared in terms of liver functions, serum lipid profiles, and hormone levels. Results: The patients had higher levels of AST, ALT, and GGT (p=0.04, p=0.01, and p=0.01, respectively). The patients also had higher cholesterol and triglyceride, and lower LDL and HDL levels than healthy children. The difference between triglyceride levels was statistically significant (p=0.04). Serum hormone levels were similar between groups. With antibiotic treatment and lifestyle modifications, all abnormal laboratory parameters returned to normal. Discussion: Children with acute brucellosis should be monitored for dyslipidemia, which can be relieved with antibiotics and lifestyle changes without using lipid lowering agents. Investigation of hormone levels in these patients is necessary only if signs and symptoms suggest an endocrine abnormality.","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43326784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zainab M. Alawad1, Suhair M. Al-Jobouri2, Ali Yakub Majid3 1Physiology Department, College of Medicine, Baghdad University, Bab Al Muadam, 2Community Medicine Department, College of Medicine, Baghdad University, Bab Al Muadam, 3Consultant Physician, Poisoning Consultation Center, Medical City, Baghdad, Iraq Lead level in Iraqi children with autism Lead among children with autism in Iraq. Is it a potential factor?
Zainab M. Alawad1, Suhair M. Al- jobouri2, Ali Yakub Majid3 1巴格达大学医学院生理学系，Bab Al Muadam, 2巴格达大学医学院社区医学系，3伊拉克巴格达医疗城中毒咨询中心顾问医师伊拉克自闭症儿童铅水平伊拉克自闭症儿童铅水平这是一个潜在的因素吗?
{"title":"Lead among children with autism in Iraq. Is it a potential factor?","authors":"Zainab M. Alawad","doi":"10.4328/jcam.5908","DOIUrl":"https://doi.org/10.4328/jcam.5908","url":null,"abstract":"Zainab M. Alawad1, Suhair M. Al-Jobouri2, Ali Yakub Majid3 1Physiology Department, College of Medicine, Baghdad University, Bab Al Muadam, 2Community Medicine Department, College of Medicine, Baghdad University, Bab Al Muadam, 3Consultant Physician, Poisoning Consultation Center, Medical City, Baghdad, Iraq Lead level in Iraqi children with autism Lead among children with autism in Iraq. Is it a potential factor?","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44149166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmet Karatas1, Ebru Canakci2, Ismail Yildiz3 1Department of Internal Medicine, Division of Nephrology, 2Department of Anesthesiology and Reanimation, 3Clinic of Intensive Care Medicine, Training and Research Hospital, Ordu University, School of Medicine, Ordu, Turkey Caval index in ventilator associated pneumonia Bun/creatinine ratio and the inferior vena cava collapsibility index in ventilator associated pneumonia
Ahmet Karatas1, Ebru Canakci2, Ismail Yildiz3 1 Ordu大学医学院培训与研究医院内科肾内科，2麻醉与复苏科，3 Ordu医学院重症监护医学诊所，土耳其呼吸机相关性肺炎下腔静脉指数Bun/肌酐比值及呼吸机相关性肺炎下腔静脉塌陷指数
{"title":"Bun/creatinine ratio and the inferior vena cava collapsibility index in ventilator associated pneumonia","authors":"A. Karataş","doi":"10.4328/jcam.6062","DOIUrl":"https://doi.org/10.4328/jcam.6062","url":null,"abstract":"Ahmet Karatas1, Ebru Canakci2, Ismail Yildiz3 1Department of Internal Medicine, Division of Nephrology, 2Department of Anesthesiology and Reanimation, 3Clinic of Intensive Care Medicine, Training and Research Hospital, Ordu University, School of Medicine, Ordu, Turkey Caval index in ventilator associated pneumonia Bun/creatinine ratio and the inferior vena cava collapsibility index in ventilator associated pneumonia","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44934437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ghada Ebrahim El Refaye1, Afaf Mohamed Botla1, Hossam Al-Din Hussein2, Hamada Ahmed Hamada3, Amir N. Wadee4 1Department of Physical Therapy for Women’s Health, Faculty of Physical therapy, Cairo University, 2Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University, 3Department of Biomechanics, Faculty of Physical Therapy, Cairo University, 4Department of Basic Science for Physical Therapy, Faculty of Physical Therapy, Cairo University, Egypt Electromagnetic field versus diclofenac drugs on primary dysmenorrhea Electromagnetic field versus diclofenac drugs on primary dysmenorrhea: A single-blind randomized controlled trial
Ghada Ebrahim El Refaye1、Afaf Mohamed Botla1、Hossam Al Din Hussein2、Hamada Ahmed Hamada3、Amir N.Wadee4 1开罗大学物理治疗学院妇女健康物理治疗系、2爱资哈尔大学医学院妇产科、3开罗大学物理治疗学院生物力学系，4埃及开罗大学物理治疗学院物理治疗基础科学系电磁场与双氯芬酸药物治疗原发性痛经电磁场与双氯芬酸药物对原发性闭经的疗效：一项单盲随机对照试验
{"title":"Electromagnetic field versus diclofenac drugs on primary dysmenorrhea: A single-blind randomized controlled trial","authors":"Ghada Ebrahim El Refaye","doi":"10.4328/JCAM.5890","DOIUrl":"https://doi.org/10.4328/JCAM.5890","url":null,"abstract":"Ghada Ebrahim El Refaye1, Afaf Mohamed Botla1, Hossam Al-Din Hussein2, Hamada Ahmed Hamada3, Amir N. Wadee4 1Department of Physical Therapy for Women’s Health, Faculty of Physical therapy, Cairo University, 2Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University, 3Department of Biomechanics, Faculty of Physical Therapy, Cairo University, 4Department of Basic Science for Physical Therapy, Faculty of Physical Therapy, Cairo University, Egypt Electromagnetic field versus diclofenac drugs on primary dysmenorrhea Electromagnetic field versus diclofenac drugs on primary dysmenorrhea: A single-blind randomized controlled trial","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43183243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nagihan Bilal1, Nursel Yurttutan2, Betul Kizildag2, Selman Sarica1, Saime Sağıroglu3, Adem Doganer3, Israfil Orhan1 1Department of Otorhinolaryngology, 2Department of Radiology, 3Department of Biostatistics and Medical Informatics, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey Assessment of mastoid volume and paranasal sinuses volume An evaluation of the effect of a change in paranasal sinus volumes on the formation of nasal polyposis and mastoid aeration
{"title":"An evaluation of the effect of a change in paranasal sinus volumes on the formation of nasal polyposis and mastoid aeration","authors":"N. Bilal","doi":"10.4328/jcam.5871","DOIUrl":"https://doi.org/10.4328/jcam.5871","url":null,"abstract":"Nagihan Bilal1, Nursel Yurttutan2, Betul Kizildag2, Selman Sarica1, Saime Sağıroglu3, Adem Doganer3, Israfil Orhan1 1Department of Otorhinolaryngology, 2Department of Radiology, 3Department of Biostatistics and Medical Informatics, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey Assessment of mastoid volume and paranasal sinuses volume An evaluation of the effect of a change in paranasal sinus volumes on the formation of nasal polyposis and mastoid aeration","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45475277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DOI: 10.4328/JCAM.5866 Received: 13.04.2018 Accepted: 01.05.2018 Published Online: 03.05.2018 Printed: 01.03.2019 J Clin Anal Med 2019;10(2): 230-4 Corresponding Author: Murat Doğan İşcanlı, Ankara Numune Training and Research Hospital, 06100, Altındağ, Ankara, Turkey. GSM: +905065641980 E-Mail: mdiscanli@gmail.com Abstract Aim: Anatomic and physiological changes make the elderly more susceptible to diseases. Elderly prisoners are more likely to get ill in comparison with their non-prisoner peers because of inadequate access to health care and medicines, and they often have referrals to emergency departments. This study evaluates the elderly inmate emergency department admissions in Turkey. Material and Method: A retrospective cross-sectional descriptive study was conducted in the emergency department of a tertiary healthcare facility with approximately 210,000 admissions annually. Inmate patients ≥65 years of age were included. The 140 total patients were categorized as Group 1 (65-84 years) or Group 2 (>85 years). Emergency referrals were grouped as surgical, medical, psychiatric disorders, and injury. Results: Correlation between categorical variables was analysed with Pearson chi-square test, and the effect of each factor on variables dependent on multiple factors was tested using logistic regression analysis. A total of 140 elderly inmates were eligible for the study. There was the highest number of patients in the medical group (n=98, 70%), and the least in the injury and psychiatric groups (n=4, 2.8%). Cardiovascular system disorders were the leading referral cause. Males had a greater hospitalization rate (p=0.033) and females had no injuries. Recurrence was higher in Group 2 (p=0.007). 92 patients (67.6%) were discharged from emergency department. The mortality rate was 2% (n=17). Discussion: The number of elderly inmates and thus the corresponding rates of acute care in the inmate population are gradually increasing. Already-overburdened EDs are usually the first referral units for all health problems of this vulnerable population in Turkey. Therefore, prisons should provide critical healthcare on-site for their medically vulnerable elderly population.
{"title":"Acute care of elderly inmates: A vulnerable patient population in emergency department from Turkey","authors":"M. İşcanlı","doi":"10.4328/jcam.5866","DOIUrl":"https://doi.org/10.4328/jcam.5866","url":null,"abstract":"DOI: 10.4328/JCAM.5866 Received: 13.04.2018 Accepted: 01.05.2018 Published Online: 03.05.2018 Printed: 01.03.2019 J Clin Anal Med 2019;10(2): 230-4 Corresponding Author: Murat Doğan İşcanlı, Ankara Numune Training and Research Hospital, 06100, Altındağ, Ankara, Turkey. GSM: +905065641980 E-Mail: mdiscanli@gmail.com Abstract Aim: Anatomic and physiological changes make the elderly more susceptible to diseases. Elderly prisoners are more likely to get ill in comparison with their non-prisoner peers because of inadequate access to health care and medicines, and they often have referrals to emergency departments. This study evaluates the elderly inmate emergency department admissions in Turkey. Material and Method: A retrospective cross-sectional descriptive study was conducted in the emergency department of a tertiary healthcare facility with approximately 210,000 admissions annually. Inmate patients ≥65 years of age were included. The 140 total patients were categorized as Group 1 (65-84 years) or Group 2 (>85 years). Emergency referrals were grouped as surgical, medical, psychiatric disorders, and injury. Results: Correlation between categorical variables was analysed with Pearson chi-square test, and the effect of each factor on variables dependent on multiple factors was tested using logistic regression analysis. A total of 140 elderly inmates were eligible for the study. There was the highest number of patients in the medical group (n=98, 70%), and the least in the injury and psychiatric groups (n=4, 2.8%). Cardiovascular system disorders were the leading referral cause. Males had a greater hospitalization rate (p=0.033) and females had no injuries. Recurrence was higher in Group 2 (p=0.007). 92 patients (67.6%) were discharged from emergency department. The mortality rate was 2% (n=17). Discussion: The number of elderly inmates and thus the corresponding rates of acute care in the inmate population are gradually increasing. Already-overburdened EDs are usually the first referral units for all health problems of this vulnerable population in Turkey. Therefore, prisons should provide critical healthcare on-site for their medically vulnerable elderly population.","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42285868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DOI: 10.4328/JCAM.5861 Received: 09.04.2018 Accepted: 21.05.2018 Publihed Online: 22.05.2018 Printed: 01.03.2019 J Clin Anal Med 2019;10(2): 250-2 Corresponding Author: Hacer Uyanikoglu, Department of Obstetrics and Gynecology, Harran University, School of Medicine, 63100, Sanliurfa, Turkey. T.: +90 4143183097 F.: +90 4143183190 E-Mail: huoglu@hotmail.com ORCID ID: 0000-0003-0316-4900 Abstract Adnexal torsion (AT) is a rare emergency condition during the pregnancy. It can occur in all three trimesters but it is less common in the third trimester. However, its diagnosis and management are more complicated in a third trimester pregnant woman. Here, we reported the management of this rare pregnancy complication during the third trimester of pregnancy in order to highlight the importance of laparoscopic intervention to avoid midline and pararectal abdominal incisions.
{"title":"Successful laparoscopic management of adnexal torsion in a third trimester pregnant woman: a case report","authors":"H. Uyanıkoğlu","doi":"10.4328/jcam.5861","DOIUrl":"https://doi.org/10.4328/jcam.5861","url":null,"abstract":"DOI: 10.4328/JCAM.5861 Received: 09.04.2018 Accepted: 21.05.2018 Publihed Online: 22.05.2018 Printed: 01.03.2019 J Clin Anal Med 2019;10(2): 250-2 Corresponding Author: Hacer Uyanikoglu, Department of Obstetrics and Gynecology, Harran University, School of Medicine, 63100, Sanliurfa, Turkey. T.: +90 4143183097 F.: +90 4143183190 E-Mail: huoglu@hotmail.com ORCID ID: 0000-0003-0316-4900 Abstract Adnexal torsion (AT) is a rare emergency condition during the pregnancy. It can occur in all three trimesters but it is less common in the third trimester. However, its diagnosis and management are more complicated in a third trimester pregnant woman. Here, we reported the management of this rare pregnancy complication during the third trimester of pregnancy in order to highlight the importance of laparoscopic intervention to avoid midline and pararectal abdominal incisions.","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42777809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DOI: 10.4328/JCAM.6116 Received: 24.12.2018 Accepted: 07.01.2019 Published Online: 14.01.2019 Printed: 01.03.2019 J Clin Anal Med 2019;10(2): 188-92 Corresponding Author: Serhat Karaman, Department of Emergency Medicine, Gaziosmanpasa University, Faculty of Medicine, 60100, Tokat, Turkey. T.: +90 3562149444 F.: +90 3562133179 E-Mail: drserhatkaraman@hotmail.com ORCID ID: 0000-0003-4554-1364 Abstract Aim: The advent of digital radiology and computerized workstations renders it very easy to measure cardiothoracic ratio (CTR) and cardiothoracic area ratio (CTAR) on chest radiographs. The aim of this study was to assess whether CTAR correlates with the left ventricular ejection fraction (EF) better than CTR in healthy individuals and patients with congestive heart failure. Material and Method: The study included 156 healthy individuals and 98 heart failure patients undergoing echocardiography and digital chest radiography. The CTR was calculated in the traditional manner, and the CTAR was taken as the ratio between the pixel counts of the cardiac area and whole thoracic area. Results: The traditional CTR showed an inverse correlation with ejection fraction in both healthy individuals (r = -0.13) and heart failure patients (r = -0.19). The CTAR showed an improved correlation (r = -0.32 for healthy individuals and r = -0.37 for heart failure patients). If it is assumed that an ejection fraction of 55% or more indicates normal cardiac function, a value of 50% or less for CTAR can be taken as normal. Discussion: Digital chest radiography is widely used as a popular technique for diagnosing various thoracic and cardiac diseases. Cardiomegaly is associated with an adverse outcome in patients with heart disease. Therefore, evaluation of heart size is an important clinical variable, and changes in heart size may be used to monitor and grade cardiac disease severity. Conclusion: Our findings suggest that the CTAR correlates better with cardiac function as assessed by the ejection fraction than the traditional CTR.
{"title":"Cardiothoracic area ratio for evaluation of ejection fraction in patients","authors":"Serhat Karaman","doi":"10.4328/jcam.6116","DOIUrl":"https://doi.org/10.4328/jcam.6116","url":null,"abstract":"DOI: 10.4328/JCAM.6116 Received: 24.12.2018 Accepted: 07.01.2019 Published Online: 14.01.2019 Printed: 01.03.2019 J Clin Anal Med 2019;10(2): 188-92 Corresponding Author: Serhat Karaman, Department of Emergency Medicine, Gaziosmanpasa University, Faculty of Medicine, 60100, Tokat, Turkey. T.: +90 3562149444 F.: +90 3562133179 E-Mail: drserhatkaraman@hotmail.com ORCID ID: 0000-0003-4554-1364 Abstract Aim: The advent of digital radiology and computerized workstations renders it very easy to measure cardiothoracic ratio (CTR) and cardiothoracic area ratio (CTAR) on chest radiographs. The aim of this study was to assess whether CTAR correlates with the left ventricular ejection fraction (EF) better than CTR in healthy individuals and patients with congestive heart failure. Material and Method: The study included 156 healthy individuals and 98 heart failure patients undergoing echocardiography and digital chest radiography. The CTR was calculated in the traditional manner, and the CTAR was taken as the ratio between the pixel counts of the cardiac area and whole thoracic area. Results: The traditional CTR showed an inverse correlation with ejection fraction in both healthy individuals (r = -0.13) and heart failure patients (r = -0.19). The CTAR showed an improved correlation (r = -0.32 for healthy individuals and r = -0.37 for heart failure patients). If it is assumed that an ejection fraction of 55% or more indicates normal cardiac function, a value of 50% or less for CTAR can be taken as normal. Discussion: Digital chest radiography is widely used as a popular technique for diagnosing various thoracic and cardiac diseases. Cardiomegaly is associated with an adverse outcome in patients with heart disease. Therefore, evaluation of heart size is an important clinical variable, and changes in heart size may be used to monitor and grade cardiac disease severity. Conclusion: Our findings suggest that the CTAR correlates better with cardiac function as assessed by the ejection fraction than the traditional CTR.","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49665536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DOI: 10.4328/JCAM.5862 Received: 09.04.2018 Accepted: 08.05.2018 Published Online: 15.05.2018 Printed: 01.03.2019 J Clin Anal Med 2019;10(2): 170-2 Corresponding Author: Saadet Celik, Medical Biochemistry, Bilecik Public Health Laboratory, Bilecik, Turkey. GSM: +905300668034 E-Mail: saadetkader@hotmail.com ORCID ID: 0000-0003-0646-946X Abstract Aim: Hemoglobinopathies are important public health problems with high mortality and morbidity rates. Additionally, they are amongst the most common inherited disorders in Turkey and can be preventable with the help of premarital screening programs. The aim of the present study was to analyse the hemoglobinopathy test results in individuals who applied to the hemoglobinopathy diagnosis centre in Bilecik/Turkey. Material and Method: In our study, hemoglobinopathy test results from January 2006 to April 2017 in Bilecik Hemoglobinopathy Diagnostic Centre were evaluated retrospectively. Blood samples from individuals who applied for pre-marriage counselling and general screening were collected and hemoglobinopathies (Hb A0, A1C, A2, F, C, D, E, and S) were screened by using High Performance Liquid Chromatography (HPLC). Results: A total of 23,676 people were included in the present study. Beta-thalassemia trait was detected in 1,317 (5.5%) and, HbA2 at a level over 3.5% was detected in 1,177 (5.0%). Additionally, elevated HbF levels were over 2% of individuals (324/23,676). The positivity of hemoglobin D and HbS traits were 0.06% (15 patients) and 0.01% (two patients) respectively. Discussion: In the present study the positive rate of HbA2 was 4.6%. When comparedThis finding was higher than the overall average rate in Turkey. The rate is similar to those in studies from Istanbul and the Mediterranean region, but it is higher than in studies from Bursa and Kocaeli. Our results indicated that premarital hemoglobinopathy screening should be continued for all partners planning to get married and for each individual in Bilecik who may potentially have a hemoglobinopathy trait.
{"title":"Evaluation of hemoglobinopathy carrier rates in Bilecik hemoglobinopathy diagnosis centre","authors":"S. Çelik","doi":"10.4328/jcam.5862","DOIUrl":"https://doi.org/10.4328/jcam.5862","url":null,"abstract":"DOI: 10.4328/JCAM.5862 Received: 09.04.2018 Accepted: 08.05.2018 Published Online: 15.05.2018 Printed: 01.03.2019 J Clin Anal Med 2019;10(2): 170-2 Corresponding Author: Saadet Celik, Medical Biochemistry, Bilecik Public Health Laboratory, Bilecik, Turkey. GSM: +905300668034 E-Mail: saadetkader@hotmail.com ORCID ID: 0000-0003-0646-946X Abstract Aim: Hemoglobinopathies are important public health problems with high mortality and morbidity rates. Additionally, they are amongst the most common inherited disorders in Turkey and can be preventable with the help of premarital screening programs. The aim of the present study was to analyse the hemoglobinopathy test results in individuals who applied to the hemoglobinopathy diagnosis centre in Bilecik/Turkey. Material and Method: In our study, hemoglobinopathy test results from January 2006 to April 2017 in Bilecik Hemoglobinopathy Diagnostic Centre were evaluated retrospectively. Blood samples from individuals who applied for pre-marriage counselling and general screening were collected and hemoglobinopathies (Hb A0, A1C, A2, F, C, D, E, and S) were screened by using High Performance Liquid Chromatography (HPLC). Results: A total of 23,676 people were included in the present study. Beta-thalassemia trait was detected in 1,317 (5.5%) and, HbA2 at a level over 3.5% was detected in 1,177 (5.0%). Additionally, elevated HbF levels were over 2% of individuals (324/23,676). The positivity of hemoglobin D and HbS traits were 0.06% (15 patients) and 0.01% (two patients) respectively. Discussion: In the present study the positive rate of HbA2 was 4.6%. When comparedThis finding was higher than the overall average rate in Turkey. The rate is similar to those in studies from Istanbul and the Mediterranean region, but it is higher than in studies from Bursa and Kocaeli. Our results indicated that premarital hemoglobinopathy screening should be continued for all partners planning to get married and for each individual in Bilecik who may potentially have a hemoglobinopathy trait.","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44696384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DOI: 10.4328/JCAM.6095 Received: 24.11.2018 Accepted: 01.12.2018 Published Online: 03.12.2018 Printed: 01.03.2019 J Clin Anal Med 2019;10(2): 243-6 Corresponding Author: Özlem Koca, Mikrobiyoloji Laboratuvarı, Atatürk Devlet Hastanesi, Antalya, Türkiye. GSM: +905422702656 E-Mail: drozlemkoca@gmail.com ORCID ID: 0000-0002-7167-7794 Abstract Aim: In the patients hospitalized in intensive care units (ICU) infectious agents of the lower respiratory tract are nosocomial pathogens that causes severe morbidity and mortality. The aim of our study is to determine the bacterial growth and antibiotic resistance profiles of bacterias isolated from endotracheal aspirate cultures (ETA) obtained from ICU’s of our hospital for the last one year. Material and Method: Between October 2017 and September 2018, ETA samples from adult intensive care units were examined retrospectively. In addition to conventional methods, identification and antibiotic susceptibilities were studied in accordance with the recommendations of the European Committee on Antimicrobial Susceptibility Testing (EUCAST) using fully automated VITEC (Biomerieux, France). Results: Of the 205 ETA specimens from adult ICU’s, 113 growths were detected in 103 patients. In ETA, 37 (32,7%) Acinetobacter baumannii, 29 (25,6%) Pseudomonas aeruginosa, 13 (11.5%) Staphylococcus aureus, 12 (%10,6) Klebsiella pneumoniae, 6 (5,3%) Escherichia coli, 4 (3,5%) Enterobacter cloacae and 2 (1,7%) Stenotrophomonas malthophiliae was isolated. Meropenem and imipenem resistance of A. baumannii was 89.1% for both, whereas it was 48,2% and 51,7% for P. auroginosa, respectively. Colistin and tigesiklin resistance was not detected for all isolates. Oxacillin resistant S.aureus strains were determined as 46.1% (6/13), while linezolid, teicoplanin, and vancomycin resistance were not detected. Discussion: Increased carbapenem resistance observed in antimicrobial susceptibility tests, for the most frequently bacterias isolated from ETA samples in ICU of our hospital, has shown the importance of the antimicrobial susceptibility testing.
{"title":"Antibiotic resistance profiles of endotracheal aspirates in intensive care unit patients","authors":"Özlem Koca","doi":"10.4328/jcam.6095","DOIUrl":"https://doi.org/10.4328/jcam.6095","url":null,"abstract":"DOI: 10.4328/JCAM.6095 Received: 24.11.2018 Accepted: 01.12.2018 Published Online: 03.12.2018 Printed: 01.03.2019 J Clin Anal Med 2019;10(2): 243-6 Corresponding Author: Özlem Koca, Mikrobiyoloji Laboratuvarı, Atatürk Devlet Hastanesi, Antalya, Türkiye. GSM: +905422702656 E-Mail: drozlemkoca@gmail.com ORCID ID: 0000-0002-7167-7794 Abstract Aim: In the patients hospitalized in intensive care units (ICU) infectious agents of the lower respiratory tract are nosocomial pathogens that causes severe morbidity and mortality. The aim of our study is to determine the bacterial growth and antibiotic resistance profiles of bacterias isolated from endotracheal aspirate cultures (ETA) obtained from ICU’s of our hospital for the last one year. Material and Method: Between October 2017 and September 2018, ETA samples from adult intensive care units were examined retrospectively. In addition to conventional methods, identification and antibiotic susceptibilities were studied in accordance with the recommendations of the European Committee on Antimicrobial Susceptibility Testing (EUCAST) using fully automated VITEC (Biomerieux, France). Results: Of the 205 ETA specimens from adult ICU’s, 113 growths were detected in 103 patients. In ETA, 37 (32,7%) Acinetobacter baumannii, 29 (25,6%) Pseudomonas aeruginosa, 13 (11.5%) Staphylococcus aureus, 12 (%10,6) Klebsiella pneumoniae, 6 (5,3%) Escherichia coli, 4 (3,5%) Enterobacter cloacae and 2 (1,7%) Stenotrophomonas malthophiliae was isolated. Meropenem and imipenem resistance of A. baumannii was 89.1% for both, whereas it was 48,2% and 51,7% for P. auroginosa, respectively. Colistin and tigesiklin resistance was not detected for all isolates. Oxacillin resistant S.aureus strains were determined as 46.1% (6/13), while linezolid, teicoplanin, and vancomycin resistance were not detected. Discussion: Increased carbapenem resistance observed in antimicrobial susceptibility tests, for the most frequently bacterias isolated from ETA samples in ICU of our hospital, has shown the importance of the antimicrobial susceptibility testing.","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45896850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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