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2000 IEEE Nuclear Science Symposium. Conference Record (Cat. No.00CH37149)最新文献

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Imaging properties evaluation of compact PSPMTs for discrete gamma cameras application 用于离散伽马相机的小型PSPMTs成像特性评估
Pub Date : 2000-10-15 DOI: 10.1109/NSSMIC.2000.950030
F. Garibaldi, F. Cusanno, G.M. Urcioli, E. Cisbani, R. Pani, A. Soluri, R. Pellegrini, R. Scafè, L. Indovina, M. Cinti, G. Trotta
Hamamatsu Photonics has recently developed a new generation of compact Position Sensitive PhotoMultiplier Tubes (PSPMT) based on metal channel dynode charge multiplication technology. R5900 family has now a range of compact tubes mainly differing for the anode structure. The models considered here, C8 and M16, also differ for active photocathode area. C8 has a crossed plate anode configuration consisting of 4X+4Y stripes and a larger active area (22/spl times/22 mm/sup 2/) while M16 has a 4/spl times/4 anode array with an active area of 18/spl times/18 mm/sup 2/. Here, the authors report their evaluation of C8 and M16 for clinical imaging applications as hand held probe, multi-PSPMT camera and tomographic ring. To this aim measurements of pulse linearity, positioning response, inter-channel gain variation and anodes cross talk were performed using a light source coupled to a 1 mm diameter optical fiber. Finally PSPMTs were optically coupled to 5 CsI(Tl) scintillating arrays with pixel size ranging between 1.5/spl times/1.5 mm/sup 2/ and 4.2/spl times/4.2 mm/sup 2/ to compare the imaging properties.
Hamamatsu Photonics最近开发了基于金属通道dynode电荷倍增技术的新一代紧凑型位置敏感光电倍增管(PSPMT)。R5900系列现在有一系列紧凑的管,主要是阳极结构不同。这里考虑的模型,C8和M16,对于有源光电阴极面积也不同。C8具有由4X+4Y条纹组成的交叉板阳极配置和更大的有效面积(22/spl倍/22 mm/sup 2/),而M16具有4/spl倍/4阳极阵列,有效面积为18/spl倍/18 mm/sup 2/。在这里,作者报告了他们对C8和M16作为手持探针,多pspmt相机和层析环的临床成像应用的评价。为了达到这个目的,测量脉冲线性度,定位响应,通道间增益变化和阳极串扰使用一个光源耦合到直径1毫米的光纤。最后,将pspmt与5个像元尺寸在1.5/spl倍/1.5 mm/sup 2/和4.2/spl倍/4.2 mm/sup 2/之间的CsI(Tl)闪烁阵列进行光学耦合,比较其成像特性。
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引用次数: 1
A new computation compression scheme based on a multifrequential approach 一种新的基于多频方法的计算压缩方案
Pub Date : 2000-10-15 DOI: 10.1109/NSSMIC.2000.950118
T. Rodet, P. Grangeat, L. Desbat
Nowadays medical applications such as functional imaging (PET and SPECT) or interventional imaging (CT fluoroscopy) can involve dynamic data. Thus, the computation time must be reduced. Therefore, the authors developed a new fast algorithm for dynamic reconstruction based on computation compression. The computation compression and data compression have the same fundamental steps of "decomposition", "quantification" and "uncompression". The authors' algorithm performs an indirect subband decomposition of f(f=/spl Sigma/f/sub i/) through Rf which is filtered. But as for data compression, they want to preserve the pertinent information only. To obtain this result, they reduce the number of components: Rf/sub i/ is filtered and backprojected only if f/sub i/ is significant (quantification step). Finally, to estimate signal, the authors uncompress the components (uncompression step). They implement their approach with a subband Fourier decomposition. But alternatively Cosinus, Wavelet or Karhunen Loeve decomposition could also be used. This algorithm allows to control the compression ratio and the signal quality. It yields an easy parallelization and leads to a computation time reduction directly related to the data compression rate.
如今的医学应用,如功能成像(PET和SPECT)或介入成像(CT透视)可以涉及动态数据。因此,必须减少计算时间。为此,作者提出了一种基于计算压缩的快速动态重构算法。计算压缩和数据压缩具有相同的“分解”、“量化”和“解压缩”的基本步骤。作者的算法通过滤波后的Rf对f(f=/spl Sigma/f/sub i/)进行间接子带分解。但在数据压缩方面,他们只想保留相关信息。为了得到这个结果,他们减少了分量的数量:只有当f/sub i/显著(量化步骤)时,才对Rf/sub i/进行滤波和反向投影。最后,为了估计信号,作者解压缩分量(解压缩步骤)。他们用子带傅里叶分解来实现他们的方法。但也可以使用Cosinus, Wavelet或Karhunen Loeve分解。该算法可以控制压缩比和信号质量。它产生了简单的并行化,并导致与数据压缩率直接相关的计算时间减少。
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引用次数: 8
Penalized weighted least-squares as a metal streak artifacts removal technique in computed tomography 作为计算机断层扫描中金属条纹伪影去除技术的惩罚加权最小二乘
Pub Date : 2000-10-15 DOI: 10.1109/NSSMIC.2000.949397
P. Sukovic, N. Clinthorne
Assesses the applicability of single-energy (SE) and dual-energy (DE) penalized weighted-least squares (PWLS) methods in the removal of metal streak artifacts. For that purpose the authors conduct experiments with a phantom containing opaque regions. Their earlier studies on computer-generated sets of data showed that both SE PWLS and DE PWLS methods are superior to a standard FBP-based method. The authors are interested to what extent the good performance of both SE and DE PWLS methods is preserved when using experimental data. Of particular relevance is that neither scatter in the body nor the polychromaticity of the X-ray source were taken into account in the computer-generated sets of data.
评估了单能量(SE)和双能量(DE)惩罚加权最小二乘(PWLS)方法在去除金属条纹伪影中的适用性。为此,作者对包含不透明区域的幻影进行了实验。他们早期对计算机生成的数据集的研究表明,SE PWLS和DE PWLS方法都优于基于fbp的标准方法。作者感兴趣的是,在使用实验数据时,SE和DE PWLS方法在多大程度上保持了良好的性能。特别相关的是,在计算机生成的数据集中,既没有考虑到人体中的散射,也没有考虑到x射线源的多色性。
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引用次数: 2
Improving the performance of small planar detectors for dedicated PET instrument 提高专用PET仪器小型平面探测器的性能
Pub Date : 2000-10-15 DOI: 10.1109/NSSMIC.2000.949203
N. Zhang, C. Thompson, C. L. Thompson, K. Nguyen
Several dedicated PET instruments for small animal and breast imaging have recently been developed. Many of these use position-sensitive photomultiplier tubes and pixelated crystals with depth encoding scheme to detect and localize gamma rays. Large area PS-PMTs show more distortion and have difficulty identifying crystal elements near their periphery. We have recently enhanced the BGO detector modules used in the positron emission mammography and animal PET systems previously developed in our laboratory by modifying the crossed anode readout resistor chain, modifying a faster timing amplifier circuit which takes the last dynode signal as event timing, and adding a new image weighting function to improve the crystal identification. The PMTs field of view have increased from 46 mm/spl times/58 mm to 56 mm/spl times/64 mm and the timing resolution of system has improved from 12.0 ns to 8.7 ns.
最近开发了几种用于小动物和乳房成像的专用PET仪器。其中许多使用位置敏感光电倍增管和像素化晶体与深度编码方案来检测和定位伽马射线。大面积ps - pmt显示出更多的畸变,并且难以识别其周围的晶体元素。我们最近通过修改交叉阳极读出电阻链,修改一个更快的时序放大电路,将最后一个dynode信号作为事件时序,并增加一个新的图像加权函数来提高晶体识别,改进了我们实验室之前开发的用于正电子发射乳房x光造影和动物PET系统的BGO探测器模块。pmt的视场从46 mm/spl倍/58 mm增加到56 mm/spl倍/64 mm,系统的定时分辨率从12.0 ns提高到8.7 ns。
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引用次数: 13
Improved I-131 SPECT resolution through modeling individual medium-energy collimator holes 通过对单个中能量准直器孔进行建模,提高了I-131 SPECT的分辨率
Pub Date : 2000-10-15 DOI: 10.1109/NSSMIC.2000.949370
D. G. González Trotter, J. Bowsher, R. Jaszczak
In previous work, a thick-septa collimator that rotates about an axis perpendicular to the collimator surface has been proposed. This collimator has thick septa which nearly eliminate septal penetration but which also block much of the image plane at any one rotation stop. The axis of rotation and the hexagonal configuration of holes are such that by summing data acquired at three rotation stops equally spaced over 360 degrees, approximately uniform sampling of the image plane is obtained. These summed data can then be reconstructed by general purpose analytic or iterative methods. However, summing the data may erase information inherent in the three, initially separate projection data sets. The present paper has two objectives: (1) to develop a method for realistically modeling the response of thick-septa collimators within iterative reconstruction and (2) to use this method to investigate whether it is beneficial to reconstruct rotating collimator projection data with the three data sets maintained as separate, rather than summed. Reconstructing with the three data sets maintained as separate has at least two advantages. First, it accelerates reconstruction significantly. In the study considered here, computation time to reach a particular bias was reduced by a factor of 3.3. Second, it results in less noise for a given bias. Both of these effects, acceleration and reduced noise, were increasingly pronounced with decreasing bias.
在以前的工作中,已经提出了一种围绕垂直于准直器表面的轴旋转的厚隔准直器。这种准直器具有厚的隔层,几乎消除了隔层穿透,但在任何一个旋转停止处也阻塞了大部分图像平面。旋转轴和孔的六角形结构是这样的,通过将在360度以上等间距的三个旋转停止处获得的数据相加,可以获得图像平面的近似均匀采样。然后可以用一般的分析或迭代方法来重建这些汇总的数据。然而,对数据求和可能会擦除三个最初独立的投影数据集中固有的信息。本文有两个目标:(1)开发一种能够真实模拟厚隔准直器在迭代重建中的响应的方法;(2)利用该方法研究在三个数据集单独保存而不是求和的情况下重建旋转准直器投影数据是否有益。将三个数据集作为独立的数据集进行重构至少有两个优点。首先,它显著加快了重建速度。在这里考虑的研究中,达到特定偏差的计算时间减少了3.3倍。其次,对于给定的偏置,它会产生更少的噪声。这两种效果,加速和减少噪音,随着偏差的减少而越来越明显。
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引用次数: 1
Cross strip anode imaging readouts for microchannel plate detectors 用于微通道板探测器的交叉带阳极成像读数
Pub Date : 2000-10-15 DOI: 10.1109/NSSMIC.2000.949291
O. Siegmund, A. Tremsin, J. Vallerga, J. Hull
We have developed a novel microchannel plate readout scheme, the cross strip anode. The cross strip anode has a coarse (0.5 mm) multilayer metal and ceramic cross strip pattern that encodes event positions by direct sensing of the charge on each strip and subsequent determination of the charge cloud centroid for each event. Event position encoding is accomplished with chip level preamplifiers on the anode, subsequent analog to digital conversion of individual strip charge values and a software centroid determination. We find that the spatial resolution (<7 /spl mu/m) is sufficient to resolve 12 /spl mu/m microchannel plate pores. The cross strip anode can achieve this resolution while using low MCP gain (5/spl times/10/sup 6/), thus increasing the local counting rate capacity and overall lifetime of the microchannel plate detector system. The image linearity is good enough (<5 /spl mu/m) to enable distortions in the microchannel plate hexagonal boundaries to be seen. We also discuss plans for custom chip electronics development so that encoding may be accomplished at photon counting rates >1 MHz and with low power consumption (/spl sim/2 W).
我们开发了一种新的微通道板读出方案——交叉带阳极。交叉带阳极具有粗糙的(0.5 mm)多层金属和陶瓷交叉带图案,通过直接感应每个条带上的电荷和随后确定每个事件的电荷云质心来编码事件位置。事件位置编码是通过在阳极上的芯片级前置放大器完成的,随后将各个条带电荷值进行模拟到数字转换,并通过软件确定质心。我们发现空间分辨率(1 MHz)和低功耗(/spl sim/2 W)。
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引用次数: 3
Optimization of regularization of attenuation and scatter corrected /sup 99 m/Tc cardiac SPECT studies for defect detection using hybrid images 衰减和散射校正的正则化优化/sup 99 m/Tc心脏SPECT研究用于混合图像的缺陷检测
Pub Date : 2000-10-15 DOI: 10.1109/NSSMIC.2000.949996
M. Narayanan, M. King, J. Leppo, S. Dahlberg, P.H. Pretonus, H. Gifford
Through means of an ROC study, the authors optimize the iteration number and 3-D Gaussian post-filtering of /sup 99 m/Tc cardiac emission OSEM reconstructions that implement corrections for both attenuation and scatter. Hybrid images were used for this optimization wherein perfusion defects were added artificially to clinical patient studies that were read as being normally perfused. The test conditions included 3 different iteration numbers of OSEM (1, 5 and 10), followed by 3-D Gaussian low-pass filtering at each iteration level. The level of Gaussian low-pass filtering was varied using standard deviations (/spl sigma/) of 0.6, 0.75, 1 and 1.25 pixels, in addition to a case where no post-filtering was applied. Four observers read 80 images for each of the 15 test conditions being investigated, providing confidence ratings as to the presence or absence of perfusion defects. Results indicate a slowly varying trend between very little filtering and quite heavy levels of smoothing with a gentle plateau for post-filters in the range of /spl sigma/=0.6 to 1 pixel. No significant improvement in detection accuracy was observed with increasing iteration number as long as the reconstructions are post-filtered with /spl sigma/ in the range of 0.6 to 1 pixel, suggesting that 1 complete iteration of OSEM should suffice.
通过ROC研究,作者优化了/sup 99 m/Tc心脏发射OSEM重构的迭代次数和三维高斯后滤波,实现了衰减和散射的校正。混合图像用于这种优化,其中灌注缺陷被人为地添加到临床患者研究中,这些研究被视为正常灌注。测试条件包括3种不同迭代次数的OSEM(1,5和10),然后在每个迭代级别进行三维高斯低通滤波。使用0.6、0.75、1和1.25像素的标准差(/spl sigma/)来改变高斯低通滤波的水平,以及不应用后滤波的情况。四名观察人员为正在研究的15个测试条件中的每个条件读取80张图像,提供灌注缺陷存在或不存在的置信度评级。结果表明,在非常少的滤波和相当重的平滑水平之间有一个缓慢的变化趋势,在/spl sigma/=0.6到1像素的范围内,后滤波器有一个平缓的平台。只要在0.6 ~ 1像素范围内对重构进行/spl sigma/后滤波,随着迭代次数的增加,检测精度没有明显提高,说明OSEM进行1次完整迭代就足够了。
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引用次数: 28
A control and data acquisition system for a large volume superheated droplet detector 一种大体积过热液滴探测器的控制与数据采集系统
Pub Date : 2000-10-15 DOI: 10.1109/NSSMIC.2000.949978
R. Gornea, N. Boukhira, I. Boussaroque, L. Lessard, M. Di Marco, J. Martin, J. Vinet, V. Zacek
Large-volume room-temperature superheated droplet detectors are being constructed for measuring very weakly interacting radiation fields, such as those produced by Cold Dark Matter particles (CDM particles, or Weakly Interacting Massive Particles: WIMPS), and various versions of Control and Data Acquisition systems (CDAQ) have been developed for such detectors. Large active mass droplet detectors are modular, their sensitivity is strongly temperature dependent and their operation requires measurements and control functions which are unique to this particular detection medium. We present the CDAQ systems developed for the PICASSO project for different levels of operation. Other types of applications of such detectors are also being investigated and appear promising.
人们正在建造大体积的室温过热液滴探测器,用于测量非常弱相互作用的辐射场,例如由冷暗物质粒子(CDM粒子)或弱相互作用大质量粒子(WIMPS)产生的辐射场,并且为这种探测器开发了各种版本的控制和数据采集系统(CDAQ)。大型主动质量液滴检测器是模块化的,它们的灵敏度强烈依赖于温度,它们的操作需要测量和控制功能,这些功能是这种特定检测介质所特有的。我们介绍了为毕加索项目开发的不同操作层次的CDAQ系统。这种探测器的其他类型的应用也在研究中,看起来很有希望。
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引用次数: 2
Transputer to PCI bus link module with one million programmable logic gates 转换器到PCI总线链接模块与一百万个可编程逻辑门
Pub Date : 2000-10-15 DOI: 10.1109/NSSMIC.2000.949917
S. Dhawan, D. Grollman, S. Xu
We are developing a module to take data from 16 Transputer links and take this to a PCI bus in a PC. The input data is bit serial at 20 Mbit/sec on each link. We assemble these into bytes and into 32 bit words. This is stored in a dual port SRAM till a complete event is in memory. The readout controller does formatting, checking etc. It takes a million gates to perform all the functions. This board handles steady flow of data at 30 Mbytes/sec without any loss. The TP data is sent to a PCI bus at PCI bus speeds. Then the data is shipped to a farm of 20-1 GHz Intel commodity machines using Gigabit Ethernet.
我们正在开发一个模块,从16个Transputer链路获取数据,并将其带到PC中的PCI总线。输入数据在每条链路上以20mbit /秒的速度串行化。我们把这些组合成字节和32位字。这将存储在双端口SRAM中,直到一个完整的事件在内存中。读出控制器进行格式化、检查等。需要一百万个门才能完成所有的功能。该板处理稳定的数据流在30兆/秒没有任何损失。TP数据以PCI总线速度发送到PCI总线。然后数据通过千兆以太网传输到20-1 GHz英特尔商用机器。
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引用次数: 0
Spectroscopic technique for optimal P-Z setting in /spl gamma/-ray detection 在/spl伽马射线探测中最佳P-Z设置的光谱技术
Pub Date : 2000-10-15 DOI: 10.1109/NSSMIC.2000.949882
A. Pullia
A spectroscopic technique for optimally setting the pole-zero (P-Z) compensation in a digital spectrometer has been implemented, which has substantially improved the resolution of the measurements at high count rates. Before ADC conversion the signal undergoes an analog preprocessing, consisting of pole-zero compensation and simple three-pole shaping, which is the proper antialiasing-filter shape in this context. A subsequent suitable digital filter optimizes the overall weight function and introduces digital baseline restoration. It is well known that an imperfect P-Z setting causes pulse-tail pileup which is seen as an additional noise and may impact significantly on the final resolution of the measurements, particularly at high count rates.
实现了一种在数字光谱仪中优化设置极零补偿的光谱技术,大大提高了在高计数率下测量的分辨率。在ADC转换之前,信号经过模拟预处理,包括极-零补偿和简单的三极整形,这是在这种情况下合适的抗混叠滤波器形状。随后合适的数字滤波器优化了整体权重函数,并引入了数字基线恢复。众所周知,不完美的P-Z设置会导致脉冲尾堆积,这被视为额外的噪声,并可能对测量的最终分辨率产生重大影响,特别是在高计数率下。
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引用次数: 7
期刊
2000 IEEE Nuclear Science Symposium. Conference Record (Cat. No.00CH37149)
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