Pub Date : 2024-10-01DOI: 10.1016/j.wjam.2024.09.001
Jing-wen TIAN (田静文) , Bo SUN (孙波) , Xiao-xiao ZHANG (张晓晓) , Ying KONG (孔莹)
Intracerebral hemorrhage is a major cause of death in humans, with high morbidity, mortality, and disability rates. Secondary brain injury after intracerebral hemorrhage is a consequence of brain edema and neurological dysfunction. Acupuncture is markedly effective against secondary brain injury, and various mechanisms are involved in its action, such as inhibition of inflammatory cascades, inhibition of oxidative stress, attenuation of brain edema, inhibition of nerve cell death, and regulation of neural plasticity. This paper summarizes the mechanism underlying the effects of acupuncture on secondary brain injury after intracerebral hemorrhage in recent years to provide new ideas for subsequent research.
{"title":"Research progress on the mechanism of acupuncture in the treatment of secondary brain injury after intracerebral hemorrhage","authors":"Jing-wen TIAN (田静文) , Bo SUN (孙波) , Xiao-xiao ZHANG (张晓晓) , Ying KONG (孔莹)","doi":"10.1016/j.wjam.2024.09.001","DOIUrl":"10.1016/j.wjam.2024.09.001","url":null,"abstract":"<div><div>Intracerebral hemorrhage is a major cause of death in humans, with high morbidity, mortality, and disability rates. Secondary brain injury after intracerebral hemorrhage is a consequence of brain edema and neurological dysfunction. Acupuncture is markedly effective against secondary brain injury, and various mechanisms are involved in its action, such as inhibition of inflammatory cascades, inhibition of oxidative stress, attenuation of brain edema, inhibition of nerve cell death, and regulation of neural plasticity. This paper summarizes the mechanism underlying the effects of acupuncture on secondary brain injury after intracerebral hemorrhage in recent years to provide new ideas for subsequent research.</div></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 4","pages":"Pages 277-281"},"PeriodicalIF":0.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.wjam.2024.06.001
Wei SUN (孙玮) , Ying-hua CHEN (陈英华) , Tong-yan LIU (刘同岩) , Xiao-qing SU (苏晓庆) , Rui-qi QIN (秦瑞琦)
Acupuncture can intervene with and treat vascular dementia (VD) through multiple targets and pathways. The mechanisms of its action involve inhibiting central inflammatory responses, regulating neuronal synaptic plasticity, modulating oxidative stress, reducing neuronal apoptosis, and adjusting cellular autophagy. This paper summarizes researches on the mechanisms of acupuncture treatment for VD over the past decade, aiming to provide theoretical support for the clinical application of acupuncture in treating VD and offer a reference for future in-depth research in this field.
{"title":"Research progress on the mechanism of acupuncture treatment for vascular dementia","authors":"Wei SUN (孙玮) , Ying-hua CHEN (陈英华) , Tong-yan LIU (刘同岩) , Xiao-qing SU (苏晓庆) , Rui-qi QIN (秦瑞琦)","doi":"10.1016/j.wjam.2024.06.001","DOIUrl":"10.1016/j.wjam.2024.06.001","url":null,"abstract":"<div><div>Acupuncture can intervene with and treat vascular dementia (VD) through multiple targets and pathways. The mechanisms of its action involve inhibiting central inflammatory responses, regulating neuronal synaptic plasticity, modulating oxidative stress, reducing neuronal apoptosis, and adjusting cellular autophagy. This paper summarizes researches on the mechanisms of acupuncture treatment for VD over the past decade, aiming to provide theoretical support for the clinical application of acupuncture in treating VD and offer a reference for future in-depth research in this field.</div></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 4","pages":"Pages 270-276"},"PeriodicalIF":0.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.wjam.2024.09.004
Shuo-quan RUAN (阮铄荃), Shu-ren MING (明树人), Chao-nan LI (李超楠), Jin-chuan RAN (冉津川), Bing-li CHEN (陈炳力), Wen SHU (舒文), Ting-ting DUAN (段婷婷), Wen-guang HOU (侯文光)
Objective
To observe the clinical effect of “scapular heat penetration” technique of acupuncture in treatment of scapulohumeral periarthritis.
Design
It was a single-central randomized controlled trial, the participants, outcome assessors and statisticians were blinded.
Setting
The trial was undertaken in Department of Acupuncture and Moxibustion, Yueyang Hospital of Integrated Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, from June 2021 to January 2022.
Participants
Sixty-seven patients with scalpulohumeral periarthritis were participated.
Interventions
In the control group, the routine acupuncture was given, while in the trial group, the “scapular heat penetration” technique of acupuncture was adopted. The intervention was delivered once every two days, 3 treatments a week; and one course included 9 treatments. Before the 1st treatment and after the 9th treatment, the symptoms and physical signs were observed and recorded in each group.
Outcomes
Primary outcome: the score of visual analogy scale (VAS) before treatment and after treatment completion. Secondary outcomes: the range of movement (ROM) of shoulder joint, the score of Japanese Orthopaedic Association (JOA) of shoulder joint and the infrared thermal imaging temperature around the shoulder.
Results
A total of 102 cases were collected, 72 cases of them were eligible and 5 cases were withdrawn. Sixty-seven cases were included in analysis. In the within-group comparison, VAS score, ROM and JOA score as well as the shoulder temperature were all ameliorated after 9 treatments in either the trial group or the control group, compared with those before treatment (P < 0.05). In the comparison between two groups, after 9 treatments, VAS score in the trial group was lower than that of the control group (P < 0.05); and the improvements in ROM and shoulder temperature in the trial group were better than those of the control group (P < 0.05). No adverse reactions were found in the two groups.
Conclusion
Both the “scapular heat penetration” technique of acupuncture and the conventional acupuncture are effective on scapulohumeral periarthritis. But, regarding the improvements in pain, ROM of shoulder joint, the activity of daily life and shoulder temperature, the “scapular heat penetration” technique of acupuncture is superior to the conventional acupuncture.
{"title":"“Scapular heat penetration” technique of acupuncture in treatment of scapulohumeral periarthritis: An exploratory research","authors":"Shuo-quan RUAN (阮铄荃), Shu-ren MING (明树人), Chao-nan LI (李超楠), Jin-chuan RAN (冉津川), Bing-li CHEN (陈炳力), Wen SHU (舒文), Ting-ting DUAN (段婷婷), Wen-guang HOU (侯文光)","doi":"10.1016/j.wjam.2024.09.004","DOIUrl":"10.1016/j.wjam.2024.09.004","url":null,"abstract":"<div><h3>Objective</h3><div>To observe the clinical effect of “scapular heat penetration” technique of acupuncture in treatment of scapulohumeral periarthritis.</div></div><div><h3>Design</h3><div>It was a single-central randomized controlled trial, the participants, outcome assessors and statisticians were blinded.</div></div><div><h3>Setting</h3><div>The trial was undertaken in Department of Acupuncture and Moxibustion, Yueyang Hospital of Integrated Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, from June 2021 to January 2022.</div></div><div><h3>Participants</h3><div>Sixty-seven patients with scalpulohumeral periarthritis were participated.</div></div><div><h3>Interventions</h3><div>In the control group, the routine acupuncture was given, while in the trial group, the “scapular heat penetration” technique of acupuncture was adopted. The intervention was delivered once every two days, 3 treatments a week; and one course included 9 treatments. Before the 1st treatment and after the 9th treatment, the symptoms and physical signs were observed and recorded in each group.</div></div><div><h3>Outcomes</h3><div>Primary outcome: the score of visual analogy scale (VAS) before treatment and after treatment completion. Secondary outcomes: the range of movement (ROM) of shoulder joint, the score of Japanese Orthopaedic Association (JOA) of shoulder joint and the infrared thermal imaging temperature around the shoulder.</div></div><div><h3>Results</h3><div>A total of 102 cases were collected, 72 cases of them were eligible and 5 cases were withdrawn. Sixty-seven cases were included in analysis. In the within-group comparison, VAS score, ROM and JOA score as well as the shoulder temperature were all ameliorated after 9 treatments in either the trial group or the control group, compared with those before treatment (<em>P</em> < 0.05). In the comparison between two groups, after 9 treatments, VAS score in the trial group was lower than that of the control group (<em>P</em> < 0.05); and the improvements in ROM and shoulder temperature in the trial group were better than those of the control group (<em>P</em> < 0.05). No adverse reactions were found in the two groups.</div></div><div><h3>Conclusion</h3><div>Both the “scapular heat penetration” technique of acupuncture and the conventional acupuncture are effective on scapulohumeral periarthritis. But, regarding the improvements in pain, ROM of shoulder joint, the activity of daily life and shoulder temperature, the “scapular heat penetration” technique of acupuncture is superior to the conventional acupuncture.</div></div><div><h3>Registration number</h3><div>ChiCTR1900025505</div></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 4","pages":"Pages 306-311"},"PeriodicalIF":0.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.wjam.2024.09.007
Fei XU (徐飞) , Kai-qiong JIAO (矫楷琼) , Lin-peng WANG (王麟鹏) , Fan ZHANG (张帆)
Objective
To observe the specific effects of acupuncture in middle-aged and older patients with chronic nonspecific low back pain (CNSLBP).
Methods
Sixty-six patients with CNSLBP were randomized into the acupuncture or sham acupuncture groups (n = 33). In the acupuncture group, penetrating acupuncture with a long needle was delivered at Ashi points (painful/sensitive points), and the needles were manipulated by rotating technique after deqi till patients felt distending pain. The needles were retained in place for 30 min. Acupuncture was given three times per week for 4 weeks. In the sham acupuncture group, shallow needling was performed at non-meridian, non-acupoint, non-painful, and non-sensitive points. The needle retention and duration of treatment were the same as those of the acupuncture group before treatment, after the first intervention, after the whole treatment, and in follow-up visit (4 weeks after the whole treatment). The scores of the visual analog scale(VAS) for pain, range of movement (ROM) of the spine, and simplified Oswestry Dysfunction Index (ODI) were observed separately.
Results
Compared to the outcomes before treatment, the VAS score, spinal ROM, and simplified ODI score were lower after the first intervention, after treatment, and in follow-up visits in the acupuncture group, indicating the statistical significance (P < 0.05). When compared with the sham acupuncture group, the VAS score, spinal ROM, and simplified ODI score were significantly lower in the acupuncture group after the first intervention, after treatment, and in follow-up visit (P < 0.05). The total effective rate was 90.9% in the acupuncture group, which was significantly higher than that (75.76 %) in the sham acupuncture group (P < 0.05).
Conclusion
Acupuncture has a specific effect on CNSLBP in middle-aged and older patients and a superior effect on immediate analgesia.
{"title":"Acupuncture for chronic nonspecific low back pain in middle-aged and older patients: A randomized controlled trial","authors":"Fei XU (徐飞) , Kai-qiong JIAO (矫楷琼) , Lin-peng WANG (王麟鹏) , Fan ZHANG (张帆)","doi":"10.1016/j.wjam.2024.09.007","DOIUrl":"10.1016/j.wjam.2024.09.007","url":null,"abstract":"<div><h3>Objective</h3><div>To observe the specific effects of acupuncture in middle-aged and older patients with chronic nonspecific low back pain (CNSLBP).</div></div><div><h3>Methods</h3><div>Sixty-six patients with CNSLBP were randomized into the acupuncture or sham acupuncture groups (n = 33). In the acupuncture group, penetrating acupuncture with a long needle was delivered at <em>Ashi</em> points (painful/sensitive points), and the needles were manipulated by rotating technique after <em>deqi</em> till patients felt distending pain. The needles were retained in place for 30 min. Acupuncture was given three times per week for 4 weeks. In the sham acupuncture group, shallow needling was performed at non-meridian, non-acupoint, non-painful, and non-sensitive points. The needle retention and duration of treatment were the same as those of the acupuncture group before treatment, after the first intervention, after the whole treatment, and in follow-up visit (4 weeks after the whole treatment). The scores of the visual analog scale(VAS) for pain, range of movement (ROM) of the spine, and simplified Oswestry Dysfunction Index (ODI) were observed separately.</div></div><div><h3>Results</h3><div>Compared to the outcomes before treatment, the VAS score, spinal ROM, and simplified ODI score were lower after the first intervention, after treatment, and in follow-up visits in the acupuncture group, indicating the statistical significance (<em>P</em> < 0.05). When compared with the sham acupuncture group, the VAS score, spinal ROM, and simplified ODI score were significantly lower in the acupuncture group after the first intervention, after treatment, and in follow-up visit (<em>P</em> < 0.05). The total effective rate was 90.9% in the acupuncture group, which was significantly higher than that (75.76 %) in the sham acupuncture group (<em>P</em> < 0.05).</div></div><div><h3>Conclusion</h3><div>Acupuncture has a specific effect on CNSLBP in middle-aged and older patients and a superior effect on immediate analgesia.</div></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 4","pages":"Pages 300-305"},"PeriodicalIF":0.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.wjam.2024.09.003
Hong-Juan WANG (汪红娟), Hong TANG (唐红), Shan-Shan JIANG (江姗姗), Zhan-Fu LI (李展富), Hao-mei TIAN (田浩梅), Chu-Tao CHEN (陈楚淘)
<div><h3>Objective</h3><div>This study aimed to observe the effects of acupuncture on iron metabolism in the hippocampus of rats with cerebral ischemia-reperfusion injury (CIRI) and to explore the mechanism of acupuncture on neural repair in CIRI rats.</div></div><div><h3>Methods</h3><div>After general feeding for 3 days, 16 of 48 healthy Sprague–Dawley rats were selected according to a random number table to form a sham-occlusion group, and the models were prepared in the remaining rats. After successful modeling, the rats were randomized into model and acupuncture groups, with 16 rats in each group. The CIRI models were prepared using the modified Zea Longa suture-occlusion method. In the acupuncture group, the rats were fixed and acupuncture was delivered at “Shuigou” (GV26), “Dazhui” (GV14), and “Baihui” (GV20), and the needles were manipulated once every 15 min. In the sham-occlusion and model groups, rats were fixed without acupuncture. The intervention was performed for 30 min in each group, once every 12 h, seven times. The degree of neurological impairment was assessed by using the modified Garcia score. Cerebral blood flow (CBF) was monitored using a laser speckle blood flow imaging system. The cerebral infarction area ratio was measured using triphenyltetrazolium chloride staining. Ferric ion aggregation in brain tissue was noted using Prussian blue staining. The ferric ion and glutathione (GSH) contents of the hippocampal tissue on the ischemic side were detected using ferric ion and GSH kits. The protein expression of transferrin receptor 1 (TFR1), iron regulatory protein 2 (IRP2), and ferroportin (FPN) was detected via western blotting.</div></div><div><h3>Results</h3><div>(1) Before intervention, compared with the sham-occlusion group, the Garcia neurological score was significantly reduced in the model and acupuncture groups (both <em>P <</em> 0.01). After the intervention, compared with the sham-occlusion group, the Garcia neurological score in the model group decreased significantly (<em>P <</em> 0.01), and the score in the acupuncture group was elevated compared with the model group (<em>P <</em> 0.05). Compared to before the intervention, the Garcia neurological score increased after the intervention in the acupuncture group (<em>P <</em> 0.05). (2) Compared with the sham-occlusion group, in the model group, CBF was reduced, the infarct area was significantly enlarged, ferric ion aggregation increased in the hippocampus, the content of ferric ion increased, and that of GSH decreased significantly (both <em>P <</em> 0.01), while the protein expression of TFR1 and IRP2 was upregulated and that of FPN was downregulated (both <em>P <</em> 0.05). When compared with the model group, in the acupuncture group, CBF was increased, the infarct area was reduced (<em>P <</em> 0.01), the ferric ion aggregation was reduced in the hippocampus, the content of ferric ion decreased, and that of GSH increased significantly (<
{"title":"Effects of acupuncture on iron metabolism in the hippocampus of the rats with cerebral ischemia-reperfusion injury based on the imbalance of iron homeostasis","authors":"Hong-Juan WANG (汪红娟), Hong TANG (唐红), Shan-Shan JIANG (江姗姗), Zhan-Fu LI (李展富), Hao-mei TIAN (田浩梅), Chu-Tao CHEN (陈楚淘)","doi":"10.1016/j.wjam.2024.09.003","DOIUrl":"10.1016/j.wjam.2024.09.003","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to observe the effects of acupuncture on iron metabolism in the hippocampus of rats with cerebral ischemia-reperfusion injury (CIRI) and to explore the mechanism of acupuncture on neural repair in CIRI rats.</div></div><div><h3>Methods</h3><div>After general feeding for 3 days, 16 of 48 healthy Sprague–Dawley rats were selected according to a random number table to form a sham-occlusion group, and the models were prepared in the remaining rats. After successful modeling, the rats were randomized into model and acupuncture groups, with 16 rats in each group. The CIRI models were prepared using the modified Zea Longa suture-occlusion method. In the acupuncture group, the rats were fixed and acupuncture was delivered at “Shuigou” (GV26), “Dazhui” (GV14), and “Baihui” (GV20), and the needles were manipulated once every 15 min. In the sham-occlusion and model groups, rats were fixed without acupuncture. The intervention was performed for 30 min in each group, once every 12 h, seven times. The degree of neurological impairment was assessed by using the modified Garcia score. Cerebral blood flow (CBF) was monitored using a laser speckle blood flow imaging system. The cerebral infarction area ratio was measured using triphenyltetrazolium chloride staining. Ferric ion aggregation in brain tissue was noted using Prussian blue staining. The ferric ion and glutathione (GSH) contents of the hippocampal tissue on the ischemic side were detected using ferric ion and GSH kits. The protein expression of transferrin receptor 1 (TFR1), iron regulatory protein 2 (IRP2), and ferroportin (FPN) was detected via western blotting.</div></div><div><h3>Results</h3><div>(1) Before intervention, compared with the sham-occlusion group, the Garcia neurological score was significantly reduced in the model and acupuncture groups (both <em>P <</em> 0.01). After the intervention, compared with the sham-occlusion group, the Garcia neurological score in the model group decreased significantly (<em>P <</em> 0.01), and the score in the acupuncture group was elevated compared with the model group (<em>P <</em> 0.05). Compared to before the intervention, the Garcia neurological score increased after the intervention in the acupuncture group (<em>P <</em> 0.05). (2) Compared with the sham-occlusion group, in the model group, CBF was reduced, the infarct area was significantly enlarged, ferric ion aggregation increased in the hippocampus, the content of ferric ion increased, and that of GSH decreased significantly (both <em>P <</em> 0.01), while the protein expression of TFR1 and IRP2 was upregulated and that of FPN was downregulated (both <em>P <</em> 0.05). When compared with the model group, in the acupuncture group, CBF was increased, the infarct area was reduced (<em>P <</em> 0.01), the ferric ion aggregation was reduced in the hippocampus, the content of ferric ion decreased, and that of GSH increased significantly (<","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 4","pages":"Pages 292-299"},"PeriodicalIF":0.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.wjam.2024.09.009
Shao-peng LIU (刘少鹏) , Ming-yuan HAN (韩名媛) , Xin-yuan CAO (曹馨元) , Ying-ying ZHU (祝莹莹) , Jian-tao YIN (殷建涛) , Zhong-ren SUN (孙忠人) , Wei-bin GAO (高维滨) , Hong-na YIN (尹洪娜)
As a common clinical syndrome, voiding dysfunction is complicated in etiology, involved in a variety of diseases and associated with multi-disciplines of medicine. Either medication or surgery has not obtained the favorable effect on it. Integrated the theories of traditional Chinese medicine and Western medicine and based on the pathogenesis of the disease, the acupoint specificity and neuromodulatory effects, Professor Wei-bin GAO suggested “selecting the acupoints along the affected areas”. The acupoints located near to the lumbar, sacral and abdominal regions are dominated and stimulated with electroacupuncture at different electric waves. In treatment, electric stimulation with disperse and dense waves was adopted. The bone conduction theory of dense-wave electric field was proposed. The same neuromodulation is presented in different diseases such as neurogenic bladder, pediatric enuresis, senile nocturia, benign prostatic hyerplasia, and postpartum of postoperative urination disorders. Hence, the same therapeutic method is adoptable to different diseases with the basic acupoint composition modified.
{"title":"Professor Wei-bin GAO's experience in treatment of voiding dysfunction with electroacupuncture","authors":"Shao-peng LIU (刘少鹏) , Ming-yuan HAN (韩名媛) , Xin-yuan CAO (曹馨元) , Ying-ying ZHU (祝莹莹) , Jian-tao YIN (殷建涛) , Zhong-ren SUN (孙忠人) , Wei-bin GAO (高维滨) , Hong-na YIN (尹洪娜)","doi":"10.1016/j.wjam.2024.09.009","DOIUrl":"10.1016/j.wjam.2024.09.009","url":null,"abstract":"<div><div>As a common clinical syndrome, voiding dysfunction is complicated in etiology, involved in a variety of diseases and associated with multi-disciplines of medicine. Either medication or surgery has not obtained the favorable effect on it. Integrated the theories of traditional Chinese medicine and Western medicine and based on the pathogenesis of the disease, the acupoint specificity and neuromodulatory effects, Professor Wei-bin GAO suggested “selecting the acupoints along the affected areas”. The acupoints located near to the lumbar, sacral and abdominal regions are dominated and stimulated with electroacupuncture at different electric waves. In treatment, electric stimulation with disperse and dense waves was adopted. The bone conduction theory of dense-wave electric field was proposed. The same neuromodulation is presented in different diseases such as neurogenic bladder, pediatric enuresis, senile nocturia, benign prostatic hyerplasia, and postpartum of postoperative urination disorders. Hence, the same therapeutic method is adoptable to different diseases with the basic acupoint composition modified.</div></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 4","pages":"Pages 325-331"},"PeriodicalIF":0.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.wjam.2024.09.010
Hui-yi HUANG (黄慧仪) , Yan-yan CAI (蔡演演) , Qing-song ZHANG (张清松) , Yi-ping HUANG (黄毅平) , Zhong-hua FU (符仲华)
Objective
Fu's subcutaneous needling (FSN) has been shown potential positive effectiveness in clinical practice. However, its specific effects are still not clear. This study aims to evaluate the blinding effect of a non-penetrating sham FSN needle, developed for the first time by the authors' research team in healthy participants. Furthermore, to provide a reliable control tool to assess the specific effects of FSN.
Methods
We conducted a randomized, sham-controlled trial in 60 healthy participants divided into FSN group and sham FSN group in a 1:1 ratio. The participants were assessed according to blinding index (BI), pain intensity, sensation type and acceptability of needling.
Results
The James' BI was (0.56, 95 %CI [0.45, 0.67]) for two groups. The Bang's BI was (0.50, 95 % CI [0.24, 0.76]) in the FSN group and (−0.36, 95 % CI [−0.67, −0.07]) in the sham FSN group. There was no significant difference between needling pain intensity (P > 0.05) and type of needling sensation. A total of 96.6 % participants who received sham FSN and 86.6 % participants who received FSN considered the needling acceptable or better.
Conclusion
This study confirmed the effective blinding capability of the sham FSN needles in healthy participants, indicating that the novel non-penetrating sham FSN needle can be served as eligible control to evaluate the specific effects of FSN.
{"title":"Blinding effect of sham Fu's subcutaneous needling in a healthy population","authors":"Hui-yi HUANG (黄慧仪) , Yan-yan CAI (蔡演演) , Qing-song ZHANG (张清松) , Yi-ping HUANG (黄毅平) , Zhong-hua FU (符仲华)","doi":"10.1016/j.wjam.2024.09.010","DOIUrl":"10.1016/j.wjam.2024.09.010","url":null,"abstract":"<div><h3>Objective</h3><div><em>Fu's</em> subcutaneous needling (FSN) has been shown potential positive effectiveness in clinical practice. However, its specific effects are still not clear. This study aims to evaluate the blinding effect of a non-penetrating sham FSN needle, developed for the first time by the authors' research team in healthy participants. Furthermore, to provide a reliable control tool to assess the specific effects of FSN.</div></div><div><h3>Methods</h3><div>We conducted a randomized, sham-controlled trial in 60 healthy participants divided into FSN group and sham FSN group in a 1:1 ratio. The participants were assessed according to blinding index (BI), pain intensity, sensation type and acceptability of needling.</div></div><div><h3>Results</h3><div>The James' BI was (0.56, 95 %CI [0.45, 0.67]) for two groups. The Bang's BI was (0.50, 95 % CI [0.24, 0.76]) in the FSN group and (−0.36, 95 % CI [−0.67, −0.07]) in the sham FSN group. There was no significant difference between needling pain intensity (<em>P</em> > 0.05) and type of needling sensation. A total of 96.6 % participants who received sham FSN and 86.6 % participants who received FSN considered the needling acceptable or better.</div></div><div><h3>Conclusion</h3><div>This study confirmed the effective blinding capability of the sham FSN needles in healthy participants, indicating that the novel non-penetrating sham FSN needle can be served as eligible control to evaluate the specific effects of FSN.</div></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 4","pages":"Pages 312-317"},"PeriodicalIF":0.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143158926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.wjam.2024.09.008
Guo-jian GAO (高国建) , Hui-jun GUO (郭会军) , Xin LI (李鑫) , Yao-kai CHEN (陈耀凯) , Xing-hua TAN (谭行华) , Yu-qi YANG (杨玉琪) , Jian-ping MA (马建萍) , Shui-qing LIU (刘水青) , Quan-sheng FENG (冯全生) , Wen ZOU (邹雯) , Ji-peng DONG (董继鹏) , Jian WANG (王健) , Ying LIU (刘颖)
Objective
To assess the effects of moxibustion on immune reconstitution inflammatory syndrome (IRIS) in patients with acquired immune deficiency syndrome (AIDS) by tracking T-cell subsets over a 48-week prospective cohort study.
Methods
Patients with AIDS who had low viral loads and weakened immune systems were divided into a moxibustion group and a non-moxibustion group. The non-moxibustion group received standard western treatment, including 48 weeks of antiretroviral therapy (ART). The moxibustion group received ART combined with moxibusion therapy, administered three times weekly. Each treatment lasted 10 weeks, with four courses completed over 48 weeks, separated by 2-week breaks. At different time points, plasma levels of CD4+, CD8+, CD45RA+, CD45RO+, CD4+CD28+, CD8+CD38+, and CD4+CD38+ were compared between the two groups.
Results
A total of 200 eligible patients were included and divided into two groups, with 100 in the non-moxibustion group and 100 in the moxibustion group. At Week 24, the CD4+T cell count was (180.71 ± 79.62) cells/μL in the non-moxibustion group and (218.22 ± 82.02) cells/μL in the moxibustion group. By Week 36, the counts were (204.83 ± 96.78) cells/μL and (239.35±81.90) cells/μL, respectively. At Weeks 24 and 48, the CD8+ T cell and CD45RO+ counts were higher in the moxibustion group than in the non-moxibustion group (P < 0.05). By Week 48, the CD45RA+ count was also higher in the moxibustion group (P < 0.05). At Week 24, the CD4+CD25+ count was lower in the moxibustion group than in the non-moxibustion group (P < 0.05).
Conclusion
Moxibustion enhances immune function in patients with AIDS and IRIS by regulating T-HIVcell subsets and increasing CD4+ and CD8+ T lymphocyte counts.
{"title":"Moxibustion versus non-moxibustion for immune reconstitution inflammatory syndrome in patients with HIV: A 48-week prospective cohort study","authors":"Guo-jian GAO (高国建) , Hui-jun GUO (郭会军) , Xin LI (李鑫) , Yao-kai CHEN (陈耀凯) , Xing-hua TAN (谭行华) , Yu-qi YANG (杨玉琪) , Jian-ping MA (马建萍) , Shui-qing LIU (刘水青) , Quan-sheng FENG (冯全生) , Wen ZOU (邹雯) , Ji-peng DONG (董继鹏) , Jian WANG (王健) , Ying LIU (刘颖)","doi":"10.1016/j.wjam.2024.09.008","DOIUrl":"10.1016/j.wjam.2024.09.008","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the effects of moxibustion on immune reconstitution inflammatory syndrome (IRIS) in patients with acquired immune deficiency syndrome (AIDS) by tracking T-cell subsets over a 48-week prospective cohort study.</div></div><div><h3>Methods</h3><div>Patients with AIDS who had low viral loads and weakened immune systems were divided into a moxibustion group and a non-moxibustion group. The non-moxibustion group received standard western treatment, including 48 weeks of antiretroviral therapy (ART). The moxibustion group received ART combined with moxibusion therapy, administered three times weekly. Each treatment lasted 10 weeks, with four courses completed over 48 weeks, separated by 2-week breaks. At different time points, plasma levels of CD4<sup>+</sup>, CD8<sup>+</sup>, CD45RA<sup>+</sup>, CD45RO<sup>+</sup>, CD4<sup>+</sup>CD28<sup>+</sup>, CD8<sup>+</sup>CD38<sup>+</sup>, and CD4<sup>+</sup>CD38<sup>+</sup> were compared between the two groups.</div></div><div><h3>Results</h3><div>A total of 200 eligible patients were included and divided into two groups, with 100 in the non-moxibustion group and 100 in the moxibustion group. At Week 24, the CD4<sup>+</sup>T cell count was (180.71 ± 79.62) cells/μL in the non-moxibustion group and (218.22 ± 82.02) cells/μL in the moxibustion group. By Week 36, the counts were (204.83 ± 96.78) cells/μL and (239.35±81.90) cells/μL, respectively. At Weeks 24 and 48, the CD8<sup>+</sup> T cell and CD45RO<sup>+</sup> counts were higher in the moxibustion group than in the non-moxibustion group (<em>P</em> < 0.05). By Week 48, the CD45RA<sup>+</sup> count was also higher in the moxibustion group (<em>P</em> < 0.05). At Week 24, the CD4<sup>+</sup>CD25<sup>+</sup> count was lower in the moxibustion group than in the non-moxibustion group (<em>P</em> < 0.05).</div></div><div><h3>Conclusion</h3><div>Moxibustion enhances immune function in patients with AIDS and IRIS by regulating T-HIVcell subsets and increasing CD4<sup>+</sup> and CD8<sup>+</sup> T lymphocyte counts.</div></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 4","pages":"Pages 318-324"},"PeriodicalIF":0.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-01DOI: 10.1016/j.wjam.2024.09.005
Tian-yu MING (明恬妤), Wei-juan GANG (岗卫娟), Lan-jun SHI (施兰君), Zhen LUO (罗臻), Zi-yu TIAN (田紫煜), Xiao-yi HU (胡晓艺), Huan CHEN (陈欢), Rui-min JIAO (焦睿珉), Wen-cui XIU (修文萃), Xiang-yu HU (胡翔昱), Xiang-hong JING (景向红)
Objective
To summarize and analyze the recommendations of acupuncture and moxibustion in the global guidelines/expert consensus of chemotherapy- and/or radiotherapy-induced nausea and/or vomiting, providing a basis for the development of clinical practice guidelines on acupuncture and moxibustion for chemotherapy- and/or radiotherapy-induced nausea and/or vomiting.
Methods
We systematically searched 7 comprehensive databases, 7 guideline libraries and 4 websites of societies/associations. The retrieval period was from the inception to April 1, 2023. Two researchers independently screened the literature, extracted data, and used the Scientific, Transparent, and Applicable Rankings (STAR) tool to evaluate the quality of guidelines/expert consensus that contained acupuncture and moxibustion recommendations, and analyzed acupuncture and moxibustion recommendations in guidelines/expert consensus and their evidence base.
Results
A total of 56 guidelines/expert consensus related to the prevention and treatment of chemotherapy- and/or radiotherapy-induced nausea and/or vomiting were included, and 22 guidelines/expert consensus contained acupuncture and moxibustion recommendations, with a total of 34 recommendations on acupuncture and moxibustion (27 supports, 4 neutrals, 3 objections). The STAR evaluation (excluding 1 patient version of guideline) showed that none of the guidelines/expert consensus was with high quality, 95.24% (20/21) with medium quality, and 4.76% (1/21) with low quality. Although there were many recommendations of acupuncture and moxibustion in the existing guidelines/expert consensus, there was great heterogeneity among the acupuncture and moxibustion treatment regimens. Moreover, most of the guidelines/expert consensus did not describe the details of acupuncture and moxibustion treatment regimens, such as acupuncture and moxibustion manipulation, acupoint selection, course and timing of treatment, which is difficult to guide the clinical practice of acupuncture and moxibustion.
Conclusion
Developing clinical practice guidelines of acupuncture and moxibustion for chemotherapy- and/or radiotherapy-induced nausea and/or vomiting according to the items of the STAR tool was urgent, so as to clarify the details of acupuncture and moxibustion regimens and provide standardized treatment regimens to guide the clinical practice of acupuncture and moxibustion.
目的总结和分析全球化疗和放疗性恶心呕吐指南/专家共识中对针灸的推荐,为制定针灸治疗化疗和放疗性恶心呕吐的临床实践指南提供依据。方法系统检索7个综合性数据库、7个指南库和4个学会/协会网站。检索期自成立至2023年4月1日。两位研究者独立筛选文献、提取数据,并使用STAR (Scientific, Transparent, and Applicable Rankings)工具对包含针灸推荐的指南/专家共识的质量进行评价,并分析指南/专家共识中的针灸推荐及其证据基础。结果共纳入56份与预防和治疗化疗和放疗引起的恶心和/或呕吐相关的指南/专家共识,22份指南/专家共识包含针灸建议,其中针灸建议共34条(支持27条,中性4条,反对3条)。STAR评价(不包括1份患者版指南)显示,没有一份指南/专家共识为高质量,95.24%(20/21)为中质量,4.76%(1/21)为低质量。虽然在现有的指南/专家共识中有许多关于针灸的建议,但针灸治疗方案之间存在很大的异质性。而且,大多数指南/专家共识没有详细描述针灸治疗方案,如针灸手法、取穴、疗程和治疗时机等,难以指导针灸的临床实践。结论迫切需要根据STAR工具的项目制定针对化疗和/或放疗引起的恶心和/或呕吐的针灸临床实践指南,以明确针灸方案的细节,提供规范的治疗方案,指导针灸的临床实践。
{"title":"A global review of acupuncture and moxibustion recommendations in guidelines/expert consensus for chemotherapy- and/or radiotherapy-induced nausea and/or vomiting","authors":"Tian-yu MING (明恬妤), Wei-juan GANG (岗卫娟), Lan-jun SHI (施兰君), Zhen LUO (罗臻), Zi-yu TIAN (田紫煜), Xiao-yi HU (胡晓艺), Huan CHEN (陈欢), Rui-min JIAO (焦睿珉), Wen-cui XIU (修文萃), Xiang-yu HU (胡翔昱), Xiang-hong JING (景向红)","doi":"10.1016/j.wjam.2024.09.005","DOIUrl":"10.1016/j.wjam.2024.09.005","url":null,"abstract":"<div><h3>Objective</h3><div>To summarize and analyze the recommendations of acupuncture and moxibustion in the global guidelines/expert consensus of chemotherapy- and/or radiotherapy-induced nausea and/or vomiting, providing a basis for the development of clinical practice guidelines on acupuncture and moxibustion for chemotherapy- and/or radiotherapy-induced nausea and/or vomiting.</div></div><div><h3>Methods</h3><div>We systematically searched 7 comprehensive databases, 7 guideline libraries and 4 websites of societies/associations. The retrieval period was from the inception to April 1, 2023. Two researchers independently screened the literature, extracted data, and used the Scientific, Transparent, and Applicable Rankings (STAR) tool to evaluate the quality of guidelines/expert consensus that contained acupuncture and moxibustion recommendations, and analyzed acupuncture and moxibustion recommendations in guidelines/expert consensus and their evidence base.</div></div><div><h3>Results</h3><div>A total of 56 guidelines/expert consensus related to the prevention and treatment of chemotherapy- and/or radiotherapy-induced nausea and/or vomiting were included, and 22 guidelines/expert consensus contained acupuncture and moxibustion recommendations, with a total of 34 recommendations on acupuncture and moxibustion (27 supports, 4 neutrals, 3 objections). The STAR evaluation (excluding 1 patient version of guideline) showed that none of the guidelines/expert consensus was with high quality, 95.24% (20/21) with medium quality, and 4.76% (1/21) with low quality. Although there were many recommendations of acupuncture and moxibustion in the existing guidelines/expert consensus, there was great heterogeneity among the acupuncture and moxibustion treatment regimens. Moreover, most of the guidelines/expert consensus did not describe the details of acupuncture and moxibustion treatment regimens, such as acupuncture and moxibustion manipulation, acupoint selection, course and timing of treatment, which is difficult to guide the clinical practice of acupuncture and moxibustion.</div></div><div><h3>Conclusion</h3><div>Developing clinical practice guidelines of acupuncture and moxibustion for chemotherapy- and/or radiotherapy-induced nausea and/or vomiting according to the items of the STAR tool was urgent, so as to clarify the details of acupuncture and moxibustion regimens and provide standardized treatment regimens to guide the clinical practice of acupuncture and moxibustion.</div></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 4","pages":"Pages 259-269"},"PeriodicalIF":0.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143158925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.1016/j.wjam.2024.07.001
Hao-ran CHU (储浩然) , Wei-hong LIU (刘炜宏) , Jun YANG (杨骏) , Xiao-dong WU (武晓冬) , Xiao-ming WANG (王晓明) , Jing-ji WANG (王婧吉) , Yun LIU (刘云) , Jin HU (胡进)
Technical Benchmark of Acupuncture and Moxibustion: Moxibustion was organized by the World Federation of Acupuncture–Moxibustion Societies and the revision was led by Anhui University of Chinese Medicine. This document was first issued in 2013, known as Moxibustion Manipulation. The technical benchmark of moxibustion include scope, normative reference, terms and definitions, operation and requirement and safety. This article introduces the above contents, explains the difficulties in the revision and give the suggestions for the application and popularization of this standard.
{"title":"World Federation of Acupuncture–Moxibustion Societies (WFAS) Technical Benchmark of Acupuncture and Moxibustion: Moxibustion","authors":"Hao-ran CHU (储浩然) , Wei-hong LIU (刘炜宏) , Jun YANG (杨骏) , Xiao-dong WU (武晓冬) , Xiao-ming WANG (王晓明) , Jing-ji WANG (王婧吉) , Yun LIU (刘云) , Jin HU (胡进)","doi":"10.1016/j.wjam.2024.07.001","DOIUrl":"10.1016/j.wjam.2024.07.001","url":null,"abstract":"<div><p><em>Technical Benchmark of Acupuncture and Moxibustion: Moxibustion</em> was organized by the World Federation of Acupuncture–Moxibustion Societies and the revision was led by Anhui University of Chinese Medicine. This document was first issued in 2013, known as <em>Moxibustion Manipulation</em>. The technical benchmark of moxibustion include scope, normative reference, terms and definitions, operation and requirement and safety. This article introduces the above contents, explains the difficulties in the revision and give the suggestions for the application and popularization of this standard.</p></div>","PeriodicalId":44648,"journal":{"name":"World Journal of Acupuncture-Moxibustion","volume":"34 3","pages":"Pages 237-241"},"PeriodicalIF":0.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1003525724000448/pdfft?md5=a0af299eb7a2672bad2f573b9517e6b6&pid=1-s2.0-S1003525724000448-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141697183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}