Pub Date : 2018-10-01Epub Date: 2018-10-26DOI: 10.1055/a-0747-6416
Ulf Karl-Martin Teichgräber, Judith Hackbarth
Objectives: To date, the reliability of ultrasound for the quantitative assessment of pleural effusion has been limited. In the following study, an easy and cost-effective bedside ultrasound method was developed and investigated for specific use in the intensive care unit (ICU).
Methods: 22 patients (median age: 58.5 years, range: 37-88 years, 14 men and 8 women) with a total of 31 pleural effusions were examined in the ICU. The inclusion criterion was complete visualization of the effusion on chest computed tomography (CT). The ultrasound (US) examination was performed less than 6 h after the diagnostic CT scan. The pleural effusion volume was calculated volumetrically from the CT scan data. Within 4.58 +/- 2.87 h after the CT scan, all patients were re-examined with US in the ICU. The fluid crescent's thickness was measured between each intercostal space (ICS) with the patient in a supine position and a 30° inclination of the torso. The US measurements were compared to the calculated CT volumes using regression analysis, resulting in the following formula: V=13.330 x ICS6 (V=volume of the effusion [ml]; ICS6=sonographic measurement of the thickness of the liquid crescent [mm] in the sixth ICS).
Results: A significant correlation between the sonographically measured and the CT-calculated volumes was best observed for the sixth ICS (R2=0.589; ICC=0.7469 with p<0.0001 and a 95% CI of 0.5364-0.8705).
Conclusion: The sonographic assessment of pleural effusions in a supine position and a 30° inclination of the torso is feasible for the volumetric estimation of pleural effusion. This is especially true for ICU patients with severe primary diseases and orthopnea who are unable to sit upright or lie flat.
目的:迄今为止,超声定量评估胸腔积液的可靠性受到限制。在接下来的研究中,我们开发并研究了一种简单且具有成本效益的床边超声方法,用于重症监护病房(ICU)的特定应用。方法:对22例(中位年龄58.5岁,年龄范围37 ~ 88岁,男14例,女8例)共31例胸腔积液在ICU进行检查。纳入标准是胸腔计算机断层扫描(CT)上积液的完全可视化。超声(US)检查在诊断性CT扫描后不到6小时进行。根据CT扫描数据计算胸腔积液量。CT扫描后4.58±2.87 h,所有患者在ICU复查US。在患者仰卧位和躯干倾斜30°时,测量每个肋间隙(ICS)之间的液体月牙的厚度。通过回归分析将US测量值与计算的CT体积进行比较,得出以下公式:V=13.330 x ICS6 (V=积液体积[ml];ICS6=超声测量液月牙厚度[mm]在第六ICS)。结果:超声测量的体积与ct计算的体积在第6次ICS中最具相关性(R2=0.589;结论:仰卧位和躯干倾斜30°时胸膜积液的超声评估对胸膜积液容量的估计是可行的。对于患有严重原发疾病的ICU患者和无法坐直或平躺的骨科患者尤其如此。
{"title":"Sonographic Bedside Quantification of Pleural Effusion Compared to Computed Tomography Volumetry in ICU Patients.","authors":"Ulf Karl-Martin Teichgräber, Judith Hackbarth","doi":"10.1055/a-0747-6416","DOIUrl":"https://doi.org/10.1055/a-0747-6416","url":null,"abstract":"<p><strong>Objectives: </strong>To date, the reliability of ultrasound for the quantitative assessment of pleural effusion has been limited. In the following study, an easy and cost-effective bedside ultrasound method was developed and investigated for specific use in the intensive care unit (ICU).</p><p><strong>Methods: </strong>22 patients (median age: 58.5 years, range: 37-88 years, 14 men and 8 women) with a total of 31 pleural effusions were examined in the ICU. The inclusion criterion was complete visualization of the effusion on chest computed tomography (CT). The ultrasound (US) examination was performed less than 6 h after the diagnostic CT scan. The pleural effusion volume was calculated volumetrically from the CT scan data. Within 4.58 +/- 2.87 h after the CT scan, all patients were re-examined with US in the ICU. The fluid crescent's thickness was measured between each intercostal space (ICS) with the patient in a supine position and a 30° inclination of the torso. The US measurements were compared to the calculated CT volumes using regression analysis, resulting in the following formula: V=13.330 x ICS6 (V=volume of the effusion [ml]; ICS6=sonographic measurement of the thickness of the liquid crescent [mm] in the sixth ICS).</p><p><strong>Results: </strong>A significant correlation between the sonographically measured and the CT-calculated volumes was best observed for the sixth ICS (R2=0.589; ICC=0.7469 with p<0.0001 and a 95% CI of 0.5364-0.8705).</p><p><strong>Conclusion: </strong>The sonographic assessment of pleural effusions in a supine position and a 30° inclination of the torso is feasible for the volumetric estimation of pleural effusion. This is especially true for ICU patients with severe primary diseases and orthopnea who are unable to sit upright or lie flat.</p>","PeriodicalId":44852,"journal":{"name":"Ultrasound International Open","volume":"4 4","pages":"E131-E135"},"PeriodicalIF":3.2,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/a-0747-6416","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36617890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction Rubinstein-Taybi Syndrome (RSTS) is a rare genetic disorder (estimated birth prevalence 1 in 100,000 to 125,000). Rubinstein and Taybi originally described seven children with typical dysmorphic facial features, broad thumbs and toes, and varying degrees of mental retardation. The syndrome is associated with multiple systemic anomalies. The literature includes about a thousand reported cases since 1963. This condition is inherited in an autosomal dominant pattern, but the majority of cases are derived by de novo mutation. It may be caused by micro deletion within 16p13.3 or different mutations in the genes encoding the transcriptional coactivator CREB-binding protein and E1A-binding protein p300. The cytogenetic anomalies of RSTS remain unknown in about 37 % of patients. The diagnosis is based on clinical presentation during the early postnatal period (Spena S et al. J Pediatr Genet 2015; 4: 177-186). Only three cases of antenatal ultrasound diagnosis or detection have been reported to date. Here we present the ultrasound features of a new case.
{"title":"Early Antenatal Sonographic Findings of Rubinstein-Taybi Syndrome: Imaging of High-Arched Palate and Bilateral Abducted Thumbs on Surface Rendering Mode at 17 Weeks.","authors":"Iglika Ivancheva Simeonova-Brachot, Laure Gerony-Laffitte","doi":"10.1055/a-0637-1499","DOIUrl":"https://doi.org/10.1055/a-0637-1499","url":null,"abstract":"Introduction Rubinstein-Taybi Syndrome (RSTS) is a rare genetic disorder (estimated birth prevalence 1 in 100,000 to 125,000). Rubinstein and Taybi originally described seven children with typical dysmorphic facial features, broad thumbs and toes, and varying degrees of mental retardation. The syndrome is associated with multiple systemic anomalies. The literature includes about a thousand reported cases since 1963. This condition is inherited in an autosomal dominant pattern, but the majority of cases are derived by de novo mutation. It may be caused by micro deletion within 16p13.3 or different mutations in the genes encoding the transcriptional coactivator CREB-binding protein and E1A-binding protein p300. The cytogenetic anomalies of RSTS remain unknown in about 37 % of patients. The diagnosis is based on clinical presentation during the early postnatal period (Spena S et al. J Pediatr Genet 2015; 4: 177-186). Only three cases of antenatal ultrasound diagnosis or detection have been reported to date. Here we present the ultrasound features of a new case.","PeriodicalId":44852,"journal":{"name":"Ultrasound International Open","volume":"4 4","pages":"E139-E141"},"PeriodicalIF":3.2,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/a-0637-1499","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36669440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-01Epub Date: 2018-10-23DOI: 10.1055/a-0650-3807
Enrico Brunetti, Francesca Tamarozzi, Calum Macpherson, Carlo Filice, Markus Schindler Piontek, Adnan Kabaalioglu, Yi Dong, Nathan Atkinson, Joachim Richter, Dagmar Schreiber-Dietrich, Christoph F Dietrich
The introduction of imaging techniques in clinical practice 40 years ago changed the clinical management of many diseases, including cystic echinococcosis (CE). For the first time cysts were clearly seen before surgery. Among the available imaging techniques, ultrasound (US) has unique properties that can be used to study and manage cystic echinococcosis. It is harmless, can image almost all organs and systems, can be repeated as often as required, is portable, requires no patient preparation, is relatively inexpensive and guides diagnosis, treatment and follow-up without radiation exposure and harm to the patient. US is the only imaging technique which can be used in field settings to assess CE prevalence because it can be run even on solar power or a small generator in remote field locations. Thanks to US classifications, the concept of stage-specific treatments was introduced and because US is repeatable, the scientific community has gained a clearer understanding of the natural history of the disease. This paper reviews the scope of US in CE, describes its strengths and weaknesses compared to other imaging techniques and its relationship with serodiagnosis and discusses sonographic features that may be helpful in differential diagnosis.
{"title":"Ultrasound and Cystic Echinococcosis.","authors":"Enrico Brunetti, Francesca Tamarozzi, Calum Macpherson, Carlo Filice, Markus Schindler Piontek, Adnan Kabaalioglu, Yi Dong, Nathan Atkinson, Joachim Richter, Dagmar Schreiber-Dietrich, Christoph F Dietrich","doi":"10.1055/a-0650-3807","DOIUrl":"https://doi.org/10.1055/a-0650-3807","url":null,"abstract":"<p><p>The introduction of imaging techniques in clinical practice 40 years ago changed the clinical management of many diseases, including cystic echinococcosis (CE). For the first time cysts were clearly seen before surgery. Among the available imaging techniques, ultrasound (US) has unique properties that can be used to study and manage cystic echinococcosis. It is harmless, can image almost all organs and systems, can be repeated as often as required, is portable, requires no patient preparation, is relatively inexpensive and guides diagnosis, treatment and follow-up without radiation exposure and harm to the patient. US is the only imaging technique which can be used in field settings to assess CE prevalence because it can be run even on solar power or a small generator in remote field locations. Thanks to US classifications, the concept of stage-specific treatments was introduced and because US is repeatable, the scientific community has gained a clearer understanding of the natural history of the disease. This paper reviews the scope of US in CE, describes its strengths and weaknesses compared to other imaging techniques and its relationship with serodiagnosis and discusses sonographic features that may be helpful in differential diagnosis.</p>","PeriodicalId":44852,"journal":{"name":"Ultrasound International Open","volume":"4 3","pages":"E70-E78"},"PeriodicalIF":3.2,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/a-0650-3807","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36621256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-01Epub Date: 2018-09-12DOI: 10.1055/a-0643-4524
Malene Roland Pedersen, Palle Jørn Sloth Osther, Søren Rafael Rafaelsen
Purpose: Ultrasonography is a useful tool to measure testicular volume. According to the European Society of Urogenital Radiology, the combination of testicular atrophy and testicular microlithiasis (TML) is a risk factor for testicular cancer. Testicular atrophy is defined as a volume of less than 12 ml. The aim of this study was to compare testicular volume in patients with TML to patients with normal testicular tissue.
Materials and methods: From 2013 to 2015 we included a total of 91 adult patients with TML, and 91 adult patients with normal testicular tissue as a control group. All patients underwent scrotal B-mode ultrasound investigation including measurement of width, length and height in both testicles. Testicular volume was calculated using the formula π/6×length×height×width.
Results: The median age for patients with TML was 48 years (range: 19-94 years), and 48 years (range: 20-75 years) in patients with normal tissue. No statistically significant difference was found between total testicular volume (both testes) >30 ml in patients with TML compared to patients without (OR 0.77 (95% CI 0.43-1.38, p=0.37). However, patients with TML tended to have lower testicular volume compared to patients without TML, when investigating testicular volume below 12 ml.
Conclusion: Overall, no association was found between testicular volume and TML, but there was a trend indicating that severe atrophy is often seen in patients with TML compared to patients without TML. However, a significant difference was only found in testicular volume ≤8 ml.
目的:超声检查是测量睾丸体积的有效工具。根据欧洲泌尿生殖放射学会,睾丸萎缩和睾丸微石症(TML)的结合是睾丸癌的一个危险因素。睾丸萎缩定义为体积小于12ml。本研究的目的是比较TML患者与正常睾丸组织患者的睾丸体积。材料与方法:2013 - 2015年共纳入91例成年TML患者,91例正常睾丸组织的成年TML患者作为对照组。所有患者均行阴囊b超检查,测量双睾丸宽、长、高。睾丸体积计算公式为π/6×length×height×width。结果:TML患者的中位年龄为48岁(范围19-94岁),正常组织患者的中位年龄为48岁(范围20-75岁)。TML患者总睾丸体积(双睾丸)>30 ml与无TML患者比较,差异无统计学意义(OR 0.77) (95% CI 0.43-1.38, p=0.37)。然而,当调查睾丸体积低于12 ml时,TML患者的睾丸体积往往比没有TML的患者小。结论:总体而言,睾丸体积与TML之间没有相关性,但有一种趋势表明,与未患TML的患者相比,TML患者经常出现严重萎缩。然而,只有在睾丸体积≤8ml时才有显著差异。
{"title":"Ultrasound Evaluation of Testicular Volume in Patients with Testicular Microlithiasis.","authors":"Malene Roland Pedersen, Palle Jørn Sloth Osther, Søren Rafael Rafaelsen","doi":"10.1055/a-0643-4524","DOIUrl":"https://doi.org/10.1055/a-0643-4524","url":null,"abstract":"<p><strong>Purpose: </strong>Ultrasonography is a useful tool to measure testicular volume. According to the European Society of Urogenital Radiology, the combination of testicular atrophy and testicular microlithiasis (TML) is a risk factor for testicular cancer. Testicular atrophy is defined as a volume of less than 12 ml. The aim of this study was to compare testicular volume in patients with TML to patients with normal testicular tissue.</p><p><strong>Materials and methods: </strong>From 2013 to 2015 we included a total of 91 adult patients with TML, and 91 adult patients with normal testicular tissue as a control group. All patients underwent scrotal B-mode ultrasound investigation including measurement of width, length and height in both testicles. Testicular volume was calculated using the formula π/6×length×height×width.</p><p><strong>Results: </strong>The median age for patients with TML was 48 years (range: 19-94 years), and 48 years (range: 20-75 years) in patients with normal tissue. No statistically significant difference was found between total testicular volume (both testes) >30 ml in patients with TML compared to patients without (OR 0.77 (95% CI 0.43-1.38, p=0.37). However, patients with TML tended to have lower testicular volume compared to patients without TML, when investigating testicular volume below 12 ml.</p><p><strong>Conclusion: </strong>Overall, no association was found between testicular volume and TML, but there was a trend indicating that severe atrophy is often seen in patients with TML compared to patients without TML. However, a significant difference was only found in testicular volume ≤8 ml.</p>","PeriodicalId":44852,"journal":{"name":"Ultrasound International Open","volume":"4 3","pages":"E99-E103"},"PeriodicalIF":3.2,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/a-0643-4524","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36520134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-01Epub Date: 2018-09-24DOI: 10.1055/a-0647-1575
Judith Berger, Onno Henneman, Johann Rhemrev, Maddy Smeets, Frank Willem Jansen
Purpose: It was the aim of our study to evaluate this procedure using pelvic anatomical landmarks in order to assess the accuracy of fusion imaging and to critically evaluate the applicability in daily practice.
Methods: In a prospective, single center study, 10 patients with clinical signs of deep infiltrating endometriosis (DIE) were selected. We measured the distance between the landmark organ and the target shown by the software system (measurement 1). Measurement 2 depicts the distance between the landmark and the nearest calibration point. The calibration inaccuracy was measured as a third type of measurement (measurement 3).
Results: Measurement 1: the average distance between the organ landmark to the target was 13.6 mm (range: 0-96 mm). Measurement 2: in 31 of the 40 attempts (77.5 %), we could measure the distance from the landmark organ to the nearest calibration point. The average distance was 34.4 mm (range: 0-69 mm).Measurement 3: A perfect match was seen in 6 of 20 attempts (30.0 %). There was a deviation in 14 of the 20 attempts (70.0 %). The mean distance was 11.1 mm (range: 6-23 mm). Conclusion Although very promising, MRI-ultrasound fusion imaging (MUFI) currently cannot be readily implemented into daily practice as a routine evaluation of DIE.
{"title":"MRI-Ultrasound Fusion Imaging for Diagnosis of Deep Infiltrating Endometriosis - A Critical Appraisal.","authors":"Judith Berger, Onno Henneman, Johann Rhemrev, Maddy Smeets, Frank Willem Jansen","doi":"10.1055/a-0647-1575","DOIUrl":"https://doi.org/10.1055/a-0647-1575","url":null,"abstract":"<p><strong>Purpose: </strong>It was the aim of our study to evaluate this procedure using pelvic anatomical landmarks in order to assess the accuracy of fusion imaging and to critically evaluate the applicability in daily practice.</p><p><strong>Methods: </strong>In a prospective, single center study, 10 patients with clinical signs of deep infiltrating endometriosis (DIE) were selected. We measured the distance between the landmark organ and the target shown by the software system (measurement 1). Measurement 2 depicts the distance between the landmark and the nearest calibration point. The calibration inaccuracy was measured as a third type of measurement (measurement 3).</p><p><strong>Results: </strong>Measurement 1: the average distance between the organ landmark to the target was 13.6 mm (range: 0-96 mm). Measurement 2: in 31 of the 40 attempts (77.5 %), we could measure the distance from the landmark organ to the nearest calibration point. The average distance was 34.4 mm (range: 0-69 mm).Measurement 3: A perfect match was seen in 6 of 20 attempts (30.0 %). There was a deviation in 14 of the 20 attempts (70.0 %). The mean distance was 11.1 mm (range: 6-23 mm). Conclusion Although very promising, MRI-ultrasound fusion imaging (MUFI) currently cannot be readily implemented into daily practice as a routine evaluation of DIE.</p>","PeriodicalId":44852,"journal":{"name":"Ultrasound International Open","volume":"4 3","pages":"E85-E90"},"PeriodicalIF":3.2,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/a-0647-1575","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36526800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-01Epub Date: 2018-09-24DOI: 10.1055/a-0633-3879
Ismail Tekesin, Regina Küper-Steffen
Umbilical cord cysts are rare and the various differential diagnoses influence both management of delivery and postnatal care. Differential diagnoses of umbilical cord cysts include pseudo-cysts, omphalocele, bladder exstrophy, omphalomesenteric duct cysts and other urachal anomalies. Communication between the cyst and the fetal bladder is a hallmark of patent ductus urachus, which has an estimated incidence of 1-2:100,000 and may be detected prenatally by high-resolution ultrasound (Persutte WH et al. J Ultrasound Med 1988; 7: 399-403; Wildhaber BE et al. Arch Dis Child Fetal Neonatal Ed 2005; 90: F535-536). We present a case of a patent ductus urachus initially presenting as an allantoic cord cyst followed by edematous swelling of the umbilical cord.
{"title":"Prenatal Diagnosis and Clinical Course of a Patent Urachus Associated with an Allantoic Cord Cyst and a Giant Umbilical Cord.","authors":"Ismail Tekesin, Regina Küper-Steffen","doi":"10.1055/a-0633-3879","DOIUrl":"https://doi.org/10.1055/a-0633-3879","url":null,"abstract":"Umbilical cord cysts are rare and the various differential diagnoses influence both management of delivery and postnatal care. Differential diagnoses of umbilical cord cysts include pseudo-cysts, omphalocele, bladder exstrophy, omphalomesenteric duct cysts and other urachal anomalies. Communication between the cyst and the fetal bladder is a hallmark of patent ductus urachus, which has an estimated incidence of 1-2:100,000 and may be detected prenatally by high-resolution ultrasound (Persutte WH et al. J Ultrasound Med 1988; 7: 399-403; Wildhaber BE et al. Arch Dis Child Fetal Neonatal Ed 2005; 90: F535-536). We present a case of a patent ductus urachus initially presenting as an allantoic cord cyst followed by edematous swelling of the umbilical cord.","PeriodicalId":44852,"journal":{"name":"Ultrasound International Open","volume":"4 3","pages":"E104-E105"},"PeriodicalIF":3.2,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/a-0633-3879","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36526801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-01Epub Date: 2018-09-18DOI: 10.1055/a-0637-2437
Peter Møller Hansen, Kristoffer Lindskov Hansen, Mads Møller Pedersen, Theis Lange, Lars Lönn, Jørgen Arendt Jensen, Michael Bachmann Nielsen
Purpose: Atherosclerotic arteries are challenging to evaluate quantitatively using spectral Doppler ultrasound because of the turbulent flow conditions that occur in relation to the atherosclerotic stenoses. Vector velocity ultrasound is angle independent and provides flow information, which could potentially improve the diagnosis of arterial stenoses. The purpose of the study is to distinguish significant stenoses in the superficial femoral artery (> 50% diameter reduction) from non-significant stenoses based on velocity ratios derived from the commercially available vector velocity ultrasound technique Vector Flow Imaging (VFI).
Materials and methods: Velocity ratios (intrastenotic blood flow velocity divided by pre- or poststenotic velocity) from a total of 16 atherosclerotic stenoses and plaques in the superficial femoral artery of 11 patients were obtained using VFI. The stenosis degree, expressed as percentage diameter reduction of the artery, was determined from digital subtraction angiography and compared to the velocity ratios.
Results: A velocity ratio of 2.5 was found to distinguish clinically relevant stenoses with>50% diameter reduction from clinically non-relevant stenoses with<50% diameter reduction and the difference was statistically significant.
Conclusion: The study indicates that VFI is a potential future tool for the evaluation of arterial stenoses.
{"title":"Atherosclerotic Lesions in the Superficial Femoral Artery (SFA) Characterized with Velocity Ratios using Vector Velocity Ultrasound.","authors":"Peter Møller Hansen, Kristoffer Lindskov Hansen, Mads Møller Pedersen, Theis Lange, Lars Lönn, Jørgen Arendt Jensen, Michael Bachmann Nielsen","doi":"10.1055/a-0637-2437","DOIUrl":"https://doi.org/10.1055/a-0637-2437","url":null,"abstract":"<p><strong>Purpose: </strong>Atherosclerotic arteries are challenging to evaluate quantitatively using spectral Doppler ultrasound because of the turbulent flow conditions that occur in relation to the atherosclerotic stenoses. Vector velocity ultrasound is angle independent and provides flow information, which could potentially improve the diagnosis of arterial stenoses. The purpose of the study is to distinguish significant stenoses in the superficial femoral artery (> 50% diameter reduction) from non-significant stenoses based on velocity ratios derived from the commercially available vector velocity ultrasound technique Vector Flow Imaging (VFI).</p><p><strong>Materials and methods: </strong>Velocity ratios (intrastenotic blood flow velocity divided by pre- or poststenotic velocity) from a total of 16 atherosclerotic stenoses and plaques in the superficial femoral artery of 11 patients were obtained using VFI. The stenosis degree, expressed as percentage diameter reduction of the artery, was determined from digital subtraction angiography and compared to the velocity ratios.</p><p><strong>Results: </strong>A velocity ratio of 2.5 was found to distinguish clinically relevant stenoses with>50% diameter reduction from clinically non-relevant stenoses with<50% diameter reduction and the difference was statistically significant.</p><p><strong>Conclusion: </strong>The study indicates that VFI is a potential future tool for the evaluation of arterial stenoses.</p>","PeriodicalId":44852,"journal":{"name":"Ultrasound International Open","volume":"4 3","pages":"E79-E84"},"PeriodicalIF":3.2,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/a-0637-2437","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36522241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-01Epub Date: 2018-09-28DOI: 10.1055/a-0643-4430
Thor Bechsgaard, Kristoffer Lindskov Hansen, Andreas Brandt, Ramin Moshavegh, Julie Lyng Forman, Pia Føgh, Lotte Klitfod, Niels Bækgaard, Lars Lönn, Jørgen Arendt Jensen, Michael Bachmann Nielsen
Purpose Spectral Doppler ultrasound (SDUS) is used for quantifying reflux in lower extremity varicose veins. The technique is angle-dependent opposed to the new angle-independent Vector Flow Imaging (VFI) method. The aim of this study was to compare peak reflux velocities obtained with VFI and SDUS in patients with chronic venous disease, i. e., pathological retrograde blood flow caused by incompetent venous valves. Materials and Methods 64 patients with chronic venous disease were scanned with VFI and SDUS in the great or the small saphenous vein, and reflux velocities were compared to three assessment tools for chronic venous disease. A flow rig was used to assess the accuracy and precision of the two methods. Results The mean peak reflux velocities differed significantly (VFI: 47.4 cm/s vs. SDUS: 62.0 cm/s, p<0.001). No difference in absolute precision (p=0.18) nor relative precision (p=0.79) was found. No correlation to disease severity, according to assessment tools, was found for peak reflux velocities obtained with either method. In vitro, VFI was more accurate but equally precise when compared to SDUS. Conclusion Both VFI and SDUS detected the pathologic retrograde flow in varicose veins but measured different reflux velocities with equal precision. VFI may play a role in evaluating venous disease in the future.
{"title":"Evaluation of Peak Reflux Velocities with Vector Flow Imaging and Spectral Doppler Ultrasound in Varicose Veins.","authors":"Thor Bechsgaard, Kristoffer Lindskov Hansen, Andreas Brandt, Ramin Moshavegh, Julie Lyng Forman, Pia Føgh, Lotte Klitfod, Niels Bækgaard, Lars Lönn, Jørgen Arendt Jensen, Michael Bachmann Nielsen","doi":"10.1055/a-0643-4430","DOIUrl":"10.1055/a-0643-4430","url":null,"abstract":"<p><p><b>Purpose</b> Spectral Doppler ultrasound (SDUS) is used for quantifying reflux in lower extremity varicose veins. The technique is angle-dependent opposed to the new angle-independent Vector Flow Imaging (VFI) method. The aim of this study was to compare peak reflux velocities obtained with VFI and SDUS in patients with chronic venous disease, i. e., pathological retrograde blood flow caused by incompetent venous valves. <b>Materials and Methods</b> 64 patients with chronic venous disease were scanned with VFI and SDUS in the great or the small saphenous vein, and reflux velocities were compared to three assessment tools for chronic venous disease. A flow rig was used to assess the accuracy and precision of the two methods. <b>Results</b> The mean peak reflux velocities differed significantly (VFI: 47.4 cm/s vs. SDUS: 62.0 cm/s, p<0.001). No difference in absolute precision (p=0.18) nor relative precision (p=0.79) was found. No correlation to disease severity, according to assessment tools, was found for peak reflux velocities obtained with either method. In vitro, VFI was more accurate but equally precise when compared to SDUS. <b>Conclusion</b> Both VFI and SDUS detected the pathologic retrograde flow in varicose veins but measured different reflux velocities with equal precision. VFI may play a role in evaluating venous disease in the future.</p>","PeriodicalId":44852,"journal":{"name":"Ultrasound International Open","volume":"4 3","pages":"E91-E98"},"PeriodicalIF":3.2,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/26/cb/10-1055-a-0643-4430.PMC6162191.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36590508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction Carotidynia was originally described by Fay in 1927 [T. Fay Arch Neurol Psychiatry 1927; 18:309–15] as an atypical neuralgia consisting of pain and tenderness at the level of the carotid bifurcation. It was classified by the International Headache Society (IHS) in 1988 as a self-limiting syndrome comprising unilateral neck pain, tenderness over the carotid bifurcation, and absence of structural abnormalities, but was then removed in 2004 as a distinct disease since further research indicated that it should be regarded as a syndrome encompassing other distinct disease processes in the carotid region. Case reports [F. Comacchio et al. Acta Otorhinolaryngol Ital. 2012; 32(4): 266–9] have since described similar clinical presentations of neck pain and tenderness over the carotid bifurcation of unknown etiology, where patients undergo spontaneous remission, and imaging studies often agree on findings of perivascular inflammation, luminal integrity, and normal blood flow in the affected carotid [N. Kosaka et al. Eur Radiol. 2007;17(9):2430-3] supporting the existence of carotidynia as a distinct entity. We present a case report of carotidynia in a patient undergoing an allogeneic hematopoietic cell transplantation (HCT) with non-myeloablative conditioning where ultrasound (US) examinations and computed tomography (CT) angiography revealed the above-mentioned findings.
{"title":"Carotidynia in a Patient Receiving an Allogeneic Hematopoietic Cell Transplantation: A Case Report to Support a Disputed Entity.","authors":"Tobias Thostrup Andersen, Martin Lundsgaard Hansen, Søren Lykke Petersen, Caroline Ewertsen","doi":"10.1055/a-0647-2330","DOIUrl":"https://doi.org/10.1055/a-0647-2330","url":null,"abstract":"Introduction Carotidynia was originally described by Fay in 1927 [T. Fay Arch Neurol Psychiatry 1927; 18:309–15] as an atypical neuralgia consisting of pain and tenderness at the level of the carotid bifurcation. It was classified by the International Headache Society (IHS) in 1988 as a self-limiting syndrome comprising unilateral neck pain, tenderness over the carotid bifurcation, and absence of structural abnormalities, but was then removed in 2004 as a distinct disease since further research indicated that it should be regarded as a syndrome encompassing other distinct disease processes in the carotid region. Case reports [F. Comacchio et al. Acta Otorhinolaryngol Ital. 2012; 32(4): 266–9] have since described similar clinical presentations of neck pain and tenderness over the carotid bifurcation of unknown etiology, where patients undergo spontaneous remission, and imaging studies often agree on findings of perivascular inflammation, luminal integrity, and normal blood flow in the affected carotid [N. Kosaka et al. Eur Radiol. 2007;17(9):2430-3] supporting the existence of carotidynia as a distinct entity. We present a case report of carotidynia in a patient undergoing an allogeneic hematopoietic cell transplantation (HCT) with non-myeloablative conditioning where ultrasound (US) examinations and computed tomography (CT) angiography revealed the above-mentioned findings.","PeriodicalId":44852,"journal":{"name":"Ultrasound International Open","volume":"4 3","pages":"E106-E108"},"PeriodicalIF":3.2,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/a-0647-2330","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36604737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}