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Calcifications in Thyroid Tumors on Ultrasonography: Calcification Types and Relationship with Histopathological Type. 甲状腺肿瘤超声波检查中的钙化:钙化类型及其与组织病理学类型的关系
IF 3.2 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2018-04-01 Epub Date: 2018-07-05 DOI: 10.1055/a-0591-6070
Kaoru Kobayashi, Tomoko Fujimoto, Hisashi Ota, Mitsuyoshi Hirokawa, Tomonori Yabuta, Hiroo Masuoka, Mitsuhiro Fukushima, Takuya Higashiyama, Minoru Kihara, Yasuhiro Ito, Akihiro Miya, Akira Miyauchi

Purpose: The purpose of the study is to clarify the prevalence of calcifications within thyroid tumors on ultrasonography as well as the relationship between the calcification and histopathological types.

Materials and methods: Calcifications were classified into 6 (or 8) types according to their shape, size, and region. The prevalence of calcifications and types were investigated in new outpatients and patients who underwent thyroid surgery.

Results: Among 2,902 nodules in 2,678 new outpatients, 747 nodules (26%) had calcifications. The types showed a wide distribution. Among 941 patients with papillary carcinoma (PC), 725 patients (77%) had calcifications, and the types showed a wide distribution. 18 patients with the diffuse sclerosing variant of PC only showed punctate microcalcifications in the parenchyma (100%), 32 patients with the cyst-forming type of PC mostly fragmentary and massive types (100%), and 161 metastatic lymph nodes from PC mostly punctate microcalcifications and fragmentary types (48%). Among 337 patients with follicular carcinoma, 79 patients (23%) had calcifications, and the types were mostly fragmentary, massive, and egg-shell types. Among 41 patients with undifferentiated carcinoma, 33 patients (80%) presented with calcifications, which were mostly the massive and egg-shell types. Among 137 patients with medullary carcinoma, 99 patients (72%) had calcification, and the types showed a wide distribution. None of 173 patients with primary thyroid lymphoma had calcifications (0%).

Conclusion: Calcifications on ultrasonography can be one of the characteristic findings and a full understanding of the prevalence of calcifications and types will markedly contribute to the ultrasonic diagnosis of thyroid tumors.

目的:本研究旨在明确甲状腺肿瘤内钙化在超声波检查中的发生率以及钙化与组织病理学类型之间的关系:根据钙化的形状、大小和区域将其分为 6(或 8)种类型。在新门诊患者和接受甲状腺手术的患者中调查钙化的发生率和类型:在 2,678 名新门诊患者的 2,902 个结节中,747 个结节(26%)有钙化。钙化类型分布广泛。在941名乳头状癌(PC)患者中,725名患者(77%)有钙化,且类型分布广泛。18例弥漫硬化型PC患者仅在实质中出现点状微钙化(100%),32例囊肿形成型PC患者多为片状和块状钙化(100%),161例PC转移淋巴结多为点状微钙化和片状钙化(48%)。在 337 名滤泡癌患者中,79 名患者(23%)有钙化,钙化类型多为片段型、块状型和蛋壳型。在 41 名未分化癌患者中,有 33 名患者(80%)出现钙化,主要是块状钙化和蛋壳型钙化。在137名髓质癌患者中,99名患者(72%)有钙化,且类型分布广泛。在173名原发性甲状腺淋巴瘤患者中,没有一人出现钙化(0%):结论:钙化是超声检查的特征性发现之一,充分了解钙化的发生率和类型将大大有助于甲状腺肿瘤的超声诊断。
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引用次数: 0
The Value of an Automated Ultrasound System in the Detection of Synovitis. 自动超声系统在滑膜炎诊断中的价值。
IF 3.2 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2018-04-01 Epub Date: 2018-07-11 DOI: 10.1055/a-0612-7852
Ruediger Mueller, Mathias Grunke, Jörg Wendler, Florian Schuch, Karina Hofmann-Preiss, Ina Boettger, Rüdiger Jakobs, Hendrik Schulze-Koops, Johannes von Kempis

Background: The detection of joint swelling caused by synovitis is important for the diagnosis of inflammatory arthritis. Ultrasound (US) and MRI have proven to be more sensitive and reliable than physical examination, but they are time-consuming and expensive. The automated breast volume scanner was developed to acquire serial B-mode pictures of the female breast and these can be analyzed in all three dimensions.

Objectives: To analyze the value of automated B-mode ultrasound employing the ABVS system in detecting synovitis of the finger joints compared to manual ultrasound (mUS) and physical examination, using MRI as the gold standard.

Methods: 19 consecutive patients suffering from active rheumatoid (n=15) or psoriatic (n=4) arthritis were included. Automated and mUS were conducted with a linear array (ACUSON S2000™, 11 MHz). Multiplanar reconstruction enabled examination of the images for the presence of synovitis.

Results: 90% of the hand joints were assessable by automated ultrasound. Automated US detected 12.0, mUS 14.2, MRI 13.4, and clinical examination 4.1 positive joints - i. e. joints with synovitis - on average per patient. The inter-observer reliability of both assessors for automated and mUS, MRI, and physical examination, was 66.9%, 72.7%, 95.1%, and 88.9%, respectively. 84.3% of the joints classified as positive on MRI were confirmed by automated ultrasound, 85.5% on mUS, and 36.0 on physical examination. This translated into a sensitivity of 83.5%, 85.5%, and 36.0% for the three methods, respectively. Conclusion: Automated ultrasound is a promising ultrasound method for assessing small joints in patients with inflammatory arthritis.

背景:滑膜炎引起的关节肿胀的检测对炎性关节炎的诊断具有重要意义。超声(US)和核磁共振(MRI)已被证明比身体检查更敏感和可靠,但它们既耗时又昂贵。研制了自动乳房体积扫描仪,用于获取女性乳房的连续b模式图像,这些图像可以在三个维度上进行分析。目的:以MRI为金标准,分析采用ABVS系统的自动b超在手指关节滑膜炎诊断中的价值,并与手工超声(mUS)和体格检查进行比较。方法:连续19例活动性类风湿关节炎(n=15)或银屑病关节炎(n=4)患者。使用线性阵列(ACUSON S2000™,11 MHz)进行自动化和mUS。多平面重建使检查图像滑膜炎的存在。结果:90%的手关节可被自动超声评估。自动US检测12.0个,mUS 14.2个,MRI 13.4个,临床检查阳性关节4.1个。关节与滑膜炎-平均每个病人。自动和mUS、MRI和体格检查两种评估者的观察者间信度分别为66.9%、72.7%、95.1%和88.9%。MRI阳性关节的自动超声确诊率为84.3%,mUS确诊率为85.5%,体格检查确诊率为36.0%。这三种方法的灵敏度分别为83.5%、85.5%和36.0%。结论:自动超声是一种很有前途的评估炎性关节炎患者小关节的超声方法。
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引用次数: 2
Can Ultrasound Alone Predict Papillary Thyroid Carcinoma with Desmoid-Type Fibromatosis? A Retrospective Analysis of 13 Cases, Focusing on the Stromal Area. 单纯超声能预测甲状腺乳头状癌合并纤维瘤病吗?13例以间质区为主的回顾性分析。
IF 3.2 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2018-04-01 Epub Date: 2018-07-05 DOI: 10.1055/a-0591-6163
Kumiko Tajiri, Mitsuyoshi Hirokawa, Ayana Suzuki, Nami Takada, Hisashi Ota, Maki Oshita, Mitsuhiro Fukushima, Kaoru Kobayashi, Akira Miyauchi

Purpose: Papillary thyroid carcinoma with desmoid-type fibromatosis (PTC-DTF) is extremely rare. So far, only 4 cases describing the ultrasound findings of this variant have been reported. Here, we describe the ultrasound findings of 13 cases of PTC-DTF, focusing especially on the DTF area.

Materials and methods: We retrospectively analyzed the clinical reports, ultrasound reports, and ultrasound photographs obtained from medical records at Kuma Hospital.

Results: The patients included 8 women and 5 men with a mean age of 47.9 years. The widest dimension of the nodules ranged from 16 to 79 mm (mean: 37.5 mm). The original ultrasound reports classified the nodules as either intermediate suspicion or high suspicion. A diagnosis of PTC was suspected in 12 nodules, and anaplastic carcinoma was suspected in 1 nodule. PTC-DTF presented with an irregularly shaped nodule (100%), taller-than-wide sign (84.6%), heterogeneous echogenicity (100%), no microcalcification (76.9%), and no or mild flow signal on Doppler (75.0%). The DTF area was identified in the ultrasound photographs of 8 nodules. DTF areas were generally heterogeneous (62.5%) and more hypoechoic (71.4%) than PTC areas. Microcalcification was not observed in the DTF areas. All of the DTF areas revealed no or mild flow signal. On ultrasound elastography, the DTF areas were not stiff, and they were more elastic than the PTC areas.

Conclusion: It is difficult to predict PTC-DTF using ultrasound alone, and B-mode ultrasonography is more reliable than ultrasound elastography in the ultrasound diagnosis of malignant thyroid nodules.

目的:甲状腺乳头状癌合并硬纤维瘤病(PTC-DTF)极为罕见。迄今为止,仅报道了4例描述该变异的超声结果。在这里,我们描述了13例PTC-DTF的超声表现,特别是DTF区域。材料和方法:我们回顾性分析临床报告、超声报告和从熊马医院病历中获得的超声照片。结果:女性8例,男性5例,平均年龄47.9岁。结节最宽范围为16 ~ 79 mm(平均37.5 mm)。最初的超声报告将结节分为中度怀疑或高度怀疑。12个结节疑似PTC, 1个结节疑似间变性癌。PTC-DTF表现为不规则结节(100%),高宽征(84.6%),回声不均匀(100%),无微钙化(76.9%),多普勒无或轻度血流信号(75.0%)。在8个结节的超声照片中发现了DTF区域。DTF区普遍呈异质性(62.5%),比PTC区低回声(71.4%)。DTF区未见微钙化。所有DTF区均无或轻度血流信号。超声弹性成像显示,DTF区域不僵硬,比PTC区域更有弹性。结论:单纯超声难以预测PTC-DTF, b超超声诊断甲状腺恶性结节比超声弹性成像更可靠。
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引用次数: 7
Cytomegalovirus Infection in One Fetus with Hypoplasia of the Pons in a Diamniotic-Dichorionic Twin Pregnancy. 双绒毛膜双胎妊娠伴脑桥发育不全的胎儿巨细胞病毒感染。
IF 3.2 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2018-04-01 Epub Date: 2018-07-05 DOI: 10.1055/a-0591-5981
Reinhard Altmann, Iris Scharnreitner, Claudia Springer, Franziska Pschebezin, Wolfgang Arzt
When a cytomegalovirus infection occurs within the first 16 weeks of pregnancy, leading to intrauterine transmission, it has severe implications for the fetus. The risk of a transplacental infection in the first trimester is 40 %, and 10–15 % of these infected children show symptoms after birth. 80 % of infected children suffer from severe impairment. We present a rare case of the infection of one fetus in a diamniotic-dichorionic twin pregnancy.
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引用次数: 0
Editorial. 社论。
IF 3.2 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2018-04-01 Epub Date: 2018-07-05 DOI: 10.1055/a-0598-4115
Dear colleagues Welcome to the June 2018 issue of Ultrasound International Open. This issue works perfectly with the idea of the interdisciplinarity of Ultrasound. There are two papers dealing with the thyroid gland. The article from Kobayashi analyzes the prevalence of calcifications in thyroid tumors in US and also the relationship of these calcifications to the histopathology of the tumor. The article describes thyroid calcifications as one of the characteristic findings in defined thyroid tumors. The article from Tajiri from the same working group retrospectively analyzes the question whether Ultrasound alone can predict a special type of thyroid carcinoma. Their conclusion was that the detection of these rare carcinomas using Ultrasound alone can be difficult. Classical B-mode ultrasound seems to be the best, while elastography is less reliable. ■■■. Ultrasound Int Open 2018; 00: 00–00
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引用次数: 0
Influencing Factors of 2D Shear Wave Elastography of the Muscle - An Ex Vivo Animal Study. 肌肉二维剪切波弹性成像的影响因素--一项体内外动物研究。
IF 3.2 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2018-04-01 Epub Date: 2018-07-05 DOI: 10.1055/a-0619-6058
Marga B Rominger, Pascal Kälin, Monika Mastalerz, Katharina Martini, Volker Klingmüller, Sergio Sanabria, Thomas Frauenfelder

Objective: To evaluate measurement confounders on 2D shear wave elastography (2D-SWE) elastography of muscle.

Materials and methods: Ex vivo , porcine muscle was examined with a GE LOGIQ E9 ultrasound machine with a 9 L linear (9 MHz) and C1-6 convex probe (operating at 2.5 or 6 MHz). The influence of different confounders on mean shear wave velocity (SWVmean) was analyzed: probes, pressure applied by probe, muscle orientation, together with the impact of different machine settings such as frequency, placement depth and size of region of interest (ROI). The mean of twelve repeated SWVmean measurements (m/s) and coefficient of variation (CV; standard deviation/mean in %) were assessed for each test configuration.

Results: Reproducibility (CV) and maximum possible tissue depth of the linear probe were inferior to the convex probe. With the linear probe, there was a linear decrease of SWVmean with placement depth from 4.56 m/s to 1.81 m/s. A significant increase of SWVmean (p<0.001) was observed for larger ROI widths (range 3.96 m/s to 6.8 m/s). A change in the machine operation mode ('penetration' instead of 'general') led to a significant increase of SWVmean (p=0.04). SWVmean in the longitudinal direction of muscle was significantly higher than in cross section (p<0.001) (e. g. 4.56 m/s versus 3.42 m/s). An increase of linear probe pressure significantly increased muscle SWVmean from 5.29 m/s to 7.21 m/s (p<0.001).

Conclusions: 2D-SWE of muscle is influenced by a wealth of parameters. Therefore, standardization of measurement is advisable before application in clinical research studies and routine patient assessment.

目的:评估肌肉二维剪切波弹性成像(2D-SWE)的测量混杂因素:评估肌肉二维剪切波弹性成像(2D-SWE)的测量混杂因素:使用带有 9 L 线性(9 MHz)和 C1-6 凸探头(工作频率为 2.5 或 6 MHz)的 GE LOGIQ E9 超声波机对猪肌肉进行体外检查。分析了不同混杂因素对平均剪切波速度(SWVmean)的影响:探头、探头施加的压力、肌肉方向,以及不同机器设置(如频率、放置深度和感兴趣区(ROI)大小)的影响。对每种测试配置的 12 次重复 SWVmean 测量的平均值(米/秒)和变异系数(CV;标准偏差/平均值,单位 %)进行了评估:结果:线性探针的再现性(CV)和可能的最大组织深度均不如凸面探针。使用线性探针时,SWVmean 随放置深度从 4.56 m/s 线性下降到 1.81 m/s。SWVmean明显增加(p结论:肌肉的 2D-SWE 受大量参数的影响。因此,在应用于临床研究和常规患者评估之前,最好对测量进行标准化。
{"title":"Influencing Factors of 2D Shear Wave Elastography of the Muscle - An Ex Vivo Animal Study.","authors":"Marga B Rominger, Pascal Kälin, Monika Mastalerz, Katharina Martini, Volker Klingmüller, Sergio Sanabria, Thomas Frauenfelder","doi":"10.1055/a-0619-6058","DOIUrl":"10.1055/a-0619-6058","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate measurement confounders on 2D shear wave elastography (2D-SWE) elastography of muscle.</p><p><strong>Materials and methods: </strong><i>Ex vivo</i> , porcine muscle was examined with a GE LOGIQ E9 ultrasound machine with a 9 L linear (9 MHz) and C1-6 convex probe (operating at 2.5 or 6 MHz). The influence of different confounders on mean shear wave velocity (SWVmean) was analyzed: probes, pressure applied by probe, muscle orientation, together with the impact of different machine settings such as frequency, placement depth and size of region of interest (ROI). The mean of twelve repeated SWVmean measurements (m/s) and coefficient of variation (CV; standard deviation/mean in %) were assessed for each test configuration.</p><p><strong>Results: </strong>Reproducibility (CV) and maximum possible tissue depth of the linear probe were inferior to the convex probe. With the linear probe, there was a linear decrease of SWVmean with placement depth from 4.56 m/s to 1.81 m/s. A significant increase of SWVmean (p<0.001) was observed for larger ROI widths (range 3.96 m/s to 6.8 m/s). A change in the machine operation mode ('penetration' instead of 'general') led to a significant increase of SWVmean (p=0.04). SWVmean in the longitudinal direction of muscle was significantly higher than in cross section (p<0.001) (e. g. 4.56 m/s versus 3.42 m/s). An increase of linear probe pressure significantly increased muscle SWVmean from 5.29 m/s to 7.21 m/s (p<0.001).</p><p><strong>Conclusions: </strong>2D-SWE of muscle is influenced by a wealth of parameters. Therefore, standardization of measurement is advisable before application in clinical research studies and routine patient assessment.</p>","PeriodicalId":44852,"journal":{"name":"Ultrasound International Open","volume":"4 2","pages":"E54-E60"},"PeriodicalIF":3.2,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4f/6a/10-1055-a-0619-6058.PMC6148312.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36522240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reference Values for Shear Wave Elastography of Neck and Shoulder Muscles in Healthy Individuals. 健康人颈肩肌肉剪切波弹性成像的参考值。
IF 3.2 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2018-01-01 Epub Date: 2018-04-04 DOI: 10.1055/s-0044-102013
Caroline Ewertsen, Jonathan Carlsen, Mohammed Aftab Perveez, Henrik Schytz

Purpose: to establish reference values for ultrasound shear-wave elastography for pericranial muscles in healthy individuals (m. trapezius, m. splenius capitis, m. semispinalis capitis, m. sternocleidomastoideus and m. masseter). Also to evaluate day-to-day variations in the shear-wave speeds and evaluate the effect of the pennation of the muscle fibers, ie scanning parallel or perpendicularly to the fibers.

Materials and methods: 10 healthy individuals (5 males and 5 females) had their pericranial muscles examined with shear-wave elastography in two orthogonal planes on two different days for their dominant and non-dominant side. Mean shear wave speeds from 5 ROI's in each muscle, for each scan plane for the dominant and non-dominant side for the two days were calculated. The effect of the different parameters - muscle pennation, gender, dominant vs non-dominant side and day was evaluated.

Results: The effect of scan plane in relation to muscle pennation was statistically significant (p<0.0001). The mean shear-wave speed when scanning parallel to the muscle fibers was significantly higher than the mean shear-wave speed when scanning perpendicularly to the fibers. The day-to-day variation was statistically significant (p=0.0258), but not clinically relevant. Shear-wave speeds differed significantly between muscles. Mean shear wave speeds (m/s) for the muscles in the parallel plane were: for masseter 2.45 (SD:+/-0.25), semispinal 3.36 (SD:+/-0.75), splenius 3.04 (SD:+/-0.65), sternocleidomastoid 2.75 (SD:+/-0.23), trapezius 3.20 (SD:+/-0.27) and trapezius lateral 3.87 (SD:+/-3.87).

Conclusion: The shear wave speed variation depended on the direction of scanning. Shear wave elastography may be a method to evaluate muscle stiffness in patients suffering from chronic neck pain.

目的:建立健康人斜方肌、头脾肌、头半棘肌、胸锁乳突肌和咬肌的超声剪切波弹性成像参考值。同时评估剪切波速度的日常变化,评估肌肉纤维穿透的效果,即平行或垂直于纤维扫描。材料与方法:10例健康个体(男5例,女5例)分别于2天用横波弹性成像法在两个正交平面检测其优势侧和非优势侧的颅周肌肉。计算2天内优势侧和非优势侧各扫描平面各肌肉5个ROI的平均横波速度。评估了不同参数(肌肉笔划、性别、优势侧与非优势侧、日)的影响。结果:扫描平面对肌肉穿刺的影响有统计学意义(结论:横波速度的变化与扫描方向有关。横波弹性成像可能是一种评估慢性颈部疼痛患者肌肉僵硬度的方法。
{"title":"Reference Values for Shear Wave Elastography of Neck and Shoulder Muscles in Healthy Individuals.","authors":"Caroline Ewertsen,&nbsp;Jonathan Carlsen,&nbsp;Mohammed Aftab Perveez,&nbsp;Henrik Schytz","doi":"10.1055/s-0044-102013","DOIUrl":"https://doi.org/10.1055/s-0044-102013","url":null,"abstract":"<p><strong>Purpose: </strong>to establish reference values for ultrasound shear-wave elastography for pericranial muscles in healthy individuals (m. trapezius, m. splenius capitis, m. semispinalis capitis, m. sternocleidomastoideus and m. masseter). Also to evaluate day-to-day variations in the shear-wave speeds and evaluate the effect of the pennation of the muscle fibers, ie scanning parallel or perpendicularly to the fibers.</p><p><strong>Materials and methods: </strong>10 healthy individuals (5 males and 5 females) had their pericranial muscles examined with shear-wave elastography in two orthogonal planes on two different days for their dominant and non-dominant side. Mean shear wave speeds from 5 ROI's in each muscle, for each scan plane for the dominant and non-dominant side for the two days were calculated. The effect of the different parameters - muscle pennation, gender, dominant vs non-dominant side and day was evaluated.</p><p><strong>Results: </strong>The effect of scan plane in relation to muscle pennation was statistically significant (p<0.0001). The mean shear-wave speed when scanning parallel to the muscle fibers was significantly higher than the mean shear-wave speed when scanning perpendicularly to the fibers. The day-to-day variation was statistically significant (p=0.0258), but not clinically relevant. Shear-wave speeds differed significantly between muscles. Mean shear wave speeds (m/s) for the muscles in the parallel plane were: for masseter 2.45 (SD:+/-0.25), semispinal 3.36 (SD:+/-0.75), splenius 3.04 (SD:+/-0.65), sternocleidomastoid 2.75 (SD:+/-0.23), trapezius 3.20 (SD:+/-0.27) and trapezius lateral 3.87 (SD:+/-3.87).</p><p><strong>Conclusion: </strong>The shear wave speed variation depended on the direction of scanning. Shear wave elastography may be a method to evaluate muscle stiffness in patients suffering from chronic neck pain.</p>","PeriodicalId":44852,"journal":{"name":"Ultrasound International Open","volume":"4 1","pages":"E23-E29"},"PeriodicalIF":3.2,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-0044-102013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35987556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 26
Erratum. 勘误表。
IF 3.2 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2018-01-01 Epub Date: 2018-04-26 DOI: 10.1055/a-0621-4721
Vito Cantisani

[This corrects the article DOI: 10.1055/a-0597-3578.].

[这更正了文章DOI: 10.1055/a-0597-3578]。
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引用次数: 0
Correlation Between Fetal Weight Gain and Birth Weight with Blood Flow in the Uterine Arteries Calculated with the PixelFlux Technique. 利用PixelFlux技术计算胎儿体重增加和出生体重与子宫动脉血流的关系
IF 3.2 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2018-01-01 Epub Date: 2018-04-18 DOI: 10.1055/s-0044-102005
Helene Caroline Arneberg, Thea Anette Andersen, Liv Lorås, Hans Torp, Thomas Manfred Scholbach, Torbjørn Moe Eggebø

Introduction: The aim was to investigate correlations between fetal weight gain/day and birthweight with blood flow estimates in the uterine arteries calculated with the PixelFlux technique and with measurements from TAmax. We also aimed to examine the agreement between estimates using the two methods.

Material and methods: We conducted a prospective observational pilot study in pregnancy week 24-25 in women with risk pregnancies referred to the fetal medical centre at St. Olavs Hospital, Trondheim, Norway from March 2016 to June 2016. Blood flow in the uterine arteries was calculated using time-averaged peak velocity (TAmax) and the PixelFlux technique. PixelFlux is a method based on pixelwise calculation of spatially angle-corrected velocities and areas of all pixels inside a vessel during a heart cycle.

Results: The mean flow calculated from PixelFlux and TAmax was 811 ml/minute and 787 ml/minute, respectively. The intra-class correlation coefficient was 0.83 (95% CI 0.72-0.90) and limits of agreement were -441 ml/minute (95% CI -558 to -324 ml/minute) to 489 ml/minute (95% CI 372 to 606 ml/minute). We observed a significant correlation between mean flow calculated from PixelFlux and birthweight (r=0.41; p<0.01) and between flow calculated from PixelFlux and weight gain/day (r=0.33; p=0.02). Calculation based on TAmax was significant correlated to birthweight (r=0.34; p=0.02), but not to weight-gain/day. Pulsatile index was not correlated to flow, birthweight or fetal weight-gain/day.

Conclusions: We found significant correlations between estimated blood flow in the uterine arteries using the PixelFlux technique with fetal weight-gain/day and with birthweight. Estimates from two methods showed good agreement.

目的是研究胎儿体重增加/天和出生体重与使用PixelFlux技术和TAmax测量计算的子宫动脉血流量之间的相关性。我们还旨在检查使用这两种方法的估计之间的一致性。材料和方法:2016年3月至2016年6月,我们对在挪威特隆赫姆St. Olavs医院胎儿医疗中心转院的高危妊娠妇女进行了妊娠24-25周的前瞻性观察性试点研究。使用时间平均峰值流速(TAmax)和PixelFlux技术计算子宫动脉血流。PixelFlux是一种基于像素计算的方法,该方法在心脏周期期间计算空间角度校正的速度和血管内所有像素的面积。结果:PixelFlux和TAmax计算的平均流量分别为811 ml/min和787 ml/min。类内相关系数为0.83 (95% CI为0.72 ~ 0.90),一致性限为-441 ml/min (95% CI为-558 ~ -324 ml/min) ~ 489 ml/min (95% CI为372 ~ 606 ml/min)。我们观察到PixelFlux计算的平均流量与出生体重之间存在显著相关性(r=0.41;结论:我们发现使用PixelFlux技术估算的子宫动脉血流量与胎儿日增重和出生体重之间存在显著相关性。两种方法的估计结果一致。
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引用次数: 5
Editorial. 社论。
IF 3.2 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2018-01-01 Epub Date: 2018-04-12 DOI: 10.1055/a-0597-3578
Vita Cantisani

Dear Colleagues, it is a pleasure to introduce the present issue of Ultrasound International Open 2018.

各位同事,很高兴向大家介绍2018年超声国际公开赛。
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引用次数: 0
期刊
Ultrasound International Open
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