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Correction: Sonographic Venous Velocity Index Identifies Patients with Chronic Kidney Disease and Severe Diastolic Dysfunction 更正:超声静脉速度指数可识别慢性肾脏疾病和严重舒张功能不全的患者
IF 3.2 Q2 Medicine Pub Date : 2018-10-01 DOI: 10.1055/a-1792-6524
M. Meier, W. Jabs, M. Guthmann, G. Geppert, A. Aydin, M. Nitschke
[This corrects the article DOI: 10.1055/a-0684-9483.].
[这更正了文章DOI: 10.1055/a-0684-9483]。
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引用次数: 0
Sonographic Bedside Quantification of Pleural Effusion Compared to Computed Tomography Volumetry in ICU Patients. 超声床边量化ICU患者胸腔积液与计算机断层容积法的比较。
IF 3.2 Q2 Medicine Pub Date : 2018-10-01 Epub Date: 2018-10-26 DOI: 10.1055/a-0747-6416
Ulf Karl-Martin Teichgräber, Judith Hackbarth

Objectives: To date, the reliability of ultrasound for the quantitative assessment of pleural effusion has been limited. In the following study, an easy and cost-effective bedside ultrasound method was developed and investigated for specific use in the intensive care unit (ICU).

Methods: 22 patients (median age: 58.5 years, range: 37-88 years, 14 men and 8 women) with a total of 31 pleural effusions were examined in the ICU. The inclusion criterion was complete visualization of the effusion on chest computed tomography (CT). The ultrasound (US) examination was performed less than 6 h after the diagnostic CT scan. The pleural effusion volume was calculated volumetrically from the CT scan data. Within 4.58 +/- 2.87 h after the CT scan, all patients were re-examined with US in the ICU. The fluid crescent's thickness was measured between each intercostal space (ICS) with the patient in a supine position and a 30° inclination of the torso. The US measurements were compared to the calculated CT volumes using regression analysis, resulting in the following formula: V=13.330 x ICS6 (V=volume of the effusion [ml]; ICS6=sonographic measurement of the thickness of the liquid crescent [mm] in the sixth ICS).

Results: A significant correlation between the sonographically measured and the CT-calculated volumes was best observed for the sixth ICS (R2=0.589; ICC=0.7469 with p<0.0001 and a 95% CI of 0.5364-0.8705).

Conclusion: The sonographic assessment of pleural effusions in a supine position and a 30° inclination of the torso is feasible for the volumetric estimation of pleural effusion. This is especially true for ICU patients with severe primary diseases and orthopnea who are unable to sit upright or lie flat.

目的:迄今为止,超声定量评估胸腔积液的可靠性受到限制。在接下来的研究中,我们开发并研究了一种简单且具有成本效益的床边超声方法,用于重症监护病房(ICU)的特定应用。方法:对22例(中位年龄58.5岁,年龄范围37 ~ 88岁,男14例,女8例)共31例胸腔积液在ICU进行检查。纳入标准是胸腔计算机断层扫描(CT)上积液的完全可视化。超声(US)检查在诊断性CT扫描后不到6小时进行。根据CT扫描数据计算胸腔积液量。CT扫描后4.58±2.87 h,所有患者在ICU复查US。在患者仰卧位和躯干倾斜30°时,测量每个肋间隙(ICS)之间的液体月牙的厚度。通过回归分析将US测量值与计算的CT体积进行比较,得出以下公式:V=13.330 x ICS6 (V=积液体积[ml];ICS6=超声测量液月牙厚度[mm]在第六ICS)。结果:超声测量的体积与ct计算的体积在第6次ICS中最具相关性(R2=0.589;结论:仰卧位和躯干倾斜30°时胸膜积液的超声评估对胸膜积液容量的估计是可行的。对于患有严重原发疾病的ICU患者和无法坐直或平躺的骨科患者尤其如此。
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引用次数: 13
Early Antenatal Sonographic Findings of Rubinstein-Taybi Syndrome: Imaging of High-Arched Palate and Bilateral Abducted Thumbs on Surface Rendering Mode at 17 Weeks. Rubinstein-Taybi综合征的早期产前超声表现:17周时高弓腭和双侧拇指外展的表面渲染模式成像。
IF 3.2 Q2 Medicine Pub Date : 2018-10-01 Epub Date: 2018-10-25 DOI: 10.1055/a-0637-1499
Iglika Ivancheva Simeonova-Brachot, Laure Gerony-Laffitte
Introduction Rubinstein-Taybi Syndrome (RSTS) is a rare genetic disorder (estimated birth prevalence 1 in 100,000 to 125,000). Rubinstein and Taybi originally described seven children with typical dysmorphic facial features, broad thumbs and toes, and varying degrees of mental retardation. The syndrome is associated with multiple systemic anomalies. The literature includes about a thousand reported cases since 1963. This condition is inherited in an autosomal dominant pattern, but the majority of cases are derived by de novo mutation. It may be caused by micro deletion within 16p13.3 or different mutations in the genes encoding the transcriptional coactivator CREB-binding protein and E1A-binding protein p300. The cytogenetic anomalies of RSTS remain unknown in about 37 % of patients. The diagnosis is based on clinical presentation during the early postnatal period (Spena S et al. J Pediatr Genet 2015; 4: 177-186). Only three cases of antenatal ultrasound diagnosis or detection have been reported to date. Here we present the ultrasound features of a new case.
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引用次数: 2
Ultrasound and Cystic Echinococcosis. 超声与囊性包虫病。
IF 3.2 Q2 Medicine Pub Date : 2018-09-01 Epub Date: 2018-10-23 DOI: 10.1055/a-0650-3807
Enrico Brunetti, Francesca Tamarozzi, Calum Macpherson, Carlo Filice, Markus Schindler Piontek, Adnan Kabaalioglu, Yi Dong, Nathan Atkinson, Joachim Richter, Dagmar Schreiber-Dietrich, Christoph F Dietrich

The introduction of imaging techniques in clinical practice 40 years ago changed the clinical management of many diseases, including cystic echinococcosis (CE). For the first time cysts were clearly seen before surgery. Among the available imaging techniques, ultrasound (US) has unique properties that can be used to study and manage cystic echinococcosis. It is harmless, can image almost all organs and systems, can be repeated as often as required, is portable, requires no patient preparation, is relatively inexpensive and guides diagnosis, treatment and follow-up without radiation exposure and harm to the patient. US is the only imaging technique which can be used in field settings to assess CE prevalence because it can be run even on solar power or a small generator in remote field locations. Thanks to US classifications, the concept of stage-specific treatments was introduced and because US is repeatable, the scientific community has gained a clearer understanding of the natural history of the disease. This paper reviews the scope of US in CE, describes its strengths and weaknesses compared to other imaging techniques and its relationship with serodiagnosis and discusses sonographic features that may be helpful in differential diagnosis.

40年前影像学技术在临床实践中的引入改变了许多疾病的临床管理,包括囊性包虫病(CE)。这是第一次在手术前清楚地看到囊肿。在现有的成像技术中,超声(US)具有独特的特性,可用于研究和治疗囊性包虫病。它是无害的,可以成像几乎所有的器官和系统,可以根据需要经常重复,便携,不需要病人准备,相对便宜,指导诊断,治疗和随访,没有辐射暴露和对病人的伤害。US是唯一可以在野外环境中用于评估CE患病率的成像技术,因为它甚至可以在偏远地区的太阳能或小型发电机上运行。由于美国分类法,引入了分期治疗的概念,而且由于美国分类法是可重复的,科学界对该疾病的自然史有了更清晰的了解。本文综述了超声在CE中的应用范围,描述了超声与其他成像技术相比的优缺点及其与血清诊断的关系,并讨论了超声特征可能有助于鉴别诊断。
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引用次数: 84
Ultrasound Evaluation of Testicular Volume in Patients with Testicular Microlithiasis. 超声对睾丸微石症患者睾丸体积的评价。
IF 3.2 Q2 Medicine Pub Date : 2018-09-01 Epub Date: 2018-09-12 DOI: 10.1055/a-0643-4524
Malene Roland Pedersen, Palle Jørn Sloth Osther, Søren Rafael Rafaelsen

Purpose: Ultrasonography is a useful tool to measure testicular volume. According to the European Society of Urogenital Radiology, the combination of testicular atrophy and testicular microlithiasis (TML) is a risk factor for testicular cancer. Testicular atrophy is defined as a volume of less than 12 ml. The aim of this study was to compare testicular volume in patients with TML to patients with normal testicular tissue.

Materials and methods: From 2013 to 2015 we included a total of 91 adult patients with TML, and 91 adult patients with normal testicular tissue as a control group. All patients underwent scrotal B-mode ultrasound investigation including measurement of width, length and height in both testicles. Testicular volume was calculated using the formula π/6×length×height×width.

Results: The median age for patients with TML was 48 years (range: 19-94 years), and 48 years (range: 20-75 years) in patients with normal tissue. No statistically significant difference was found between total testicular volume (both testes) >30 ml in patients with TML compared to patients without (OR 0.77 (95% CI 0.43-1.38, p=0.37). However, patients with TML tended to have lower testicular volume compared to patients without TML, when investigating testicular volume below 12 ml.

Conclusion: Overall, no association was found between testicular volume and TML, but there was a trend indicating that severe atrophy is often seen in patients with TML compared to patients without TML. However, a significant difference was only found in testicular volume ≤8 ml.

目的:超声检查是测量睾丸体积的有效工具。根据欧洲泌尿生殖放射学会,睾丸萎缩和睾丸微石症(TML)的结合是睾丸癌的一个危险因素。睾丸萎缩定义为体积小于12ml。本研究的目的是比较TML患者与正常睾丸组织患者的睾丸体积。材料与方法:2013 - 2015年共纳入91例成年TML患者,91例正常睾丸组织的成年TML患者作为对照组。所有患者均行阴囊b超检查,测量双睾丸宽、长、高。睾丸体积计算公式为π/6×length×height×width。结果:TML患者的中位年龄为48岁(范围19-94岁),正常组织患者的中位年龄为48岁(范围20-75岁)。TML患者总睾丸体积(双睾丸)>30 ml与无TML患者比较,差异无统计学意义(OR 0.77) (95% CI 0.43-1.38, p=0.37)。然而,当调查睾丸体积低于12 ml时,TML患者的睾丸体积往往比没有TML的患者小。结论:总体而言,睾丸体积与TML之间没有相关性,但有一种趋势表明,与未患TML的患者相比,TML患者经常出现严重萎缩。然而,只有在睾丸体积≤8ml时才有显著差异。
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引用次数: 10
MRI-Ultrasound Fusion Imaging for Diagnosis of Deep Infiltrating Endometriosis - A Critical Appraisal. mri超声融合成像诊断深浸润性子宫内膜异位症的关键评价。
IF 3.2 Q2 Medicine Pub Date : 2018-09-01 Epub Date: 2018-09-24 DOI: 10.1055/a-0647-1575
Judith Berger, Onno Henneman, Johann Rhemrev, Maddy Smeets, Frank Willem Jansen

Purpose: It was the aim of our study to evaluate this procedure using pelvic anatomical landmarks in order to assess the accuracy of fusion imaging and to critically evaluate the applicability in daily practice.

Methods: In a prospective, single center study, 10 patients with clinical signs of deep infiltrating endometriosis (DIE) were selected. We measured the distance between the landmark organ and the target shown by the software system (measurement 1). Measurement 2 depicts the distance between the landmark and the nearest calibration point. The calibration inaccuracy was measured as a third type of measurement (measurement 3).

Results: Measurement 1: the average distance between the organ landmark to the target was 13.6 mm (range: 0-96 mm). Measurement 2: in 31 of the 40 attempts (77.5 %), we could measure the distance from the landmark organ to the nearest calibration point. The average distance was 34.4 mm (range: 0-69 mm).Measurement 3: A perfect match was seen in 6 of 20 attempts (30.0 %). There was a deviation in 14 of the 20 attempts (70.0 %). The mean distance was 11.1 mm (range: 6-23 mm). Conclusion Although very promising, MRI-ultrasound fusion imaging (MUFI) currently cannot be readily implemented into daily practice as a routine evaluation of DIE.

目的:我们的研究目的是利用骨盆解剖标志来评估该手术,以评估融合成像的准确性,并批判性地评估其在日常实践中的适用性。方法:在一项前瞻性、单中心研究中,选择10例临床表现为深浸润性子宫内膜异位症(DIE)的患者。我们测量了软件系统显示的地标器官与目标之间的距离(测量1)。测量2描述了地标与最近的校准点之间的距离。校正误差作为第三种测量(测量3)测量。结果:测量1:器官标志到目标的平均距离为13.6 mm(范围:0-96 mm)。测量2:在40次尝试中有31次(77.5%),我们可以测量到从地标器官到最近的校准点的距离。平均距离为34.4 mm(范围:0-69 mm)。测量3:20次尝试中有6次完美匹配(30.0%)。20次尝试中有14次出现偏差(70.0%)。平均间距11.1 mm(范围6 ~ 23 mm)。结论mri -超声融合成像(MUFI)虽然很有前景,但目前还不能作为DIE的常规评估方法应用于日常实践。
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引用次数: 9
Prenatal Diagnosis and Clinical Course of a Patent Urachus Associated with an Allantoic Cord Cyst and a Giant Umbilical Cord. 尿囊性脐带囊肿合并巨大脐带的尿囊性输卵管未闭的产前诊断和临床病程。
IF 3.2 Q2 Medicine Pub Date : 2018-09-01 Epub Date: 2018-09-24 DOI: 10.1055/a-0633-3879
Ismail Tekesin, Regina Küper-Steffen
Umbilical cord cysts are rare and the various differential diagnoses influence both management of delivery and postnatal care. Differential diagnoses of umbilical cord cysts include pseudo-cysts, omphalocele, bladder exstrophy, omphalomesenteric duct cysts and other urachal anomalies. Communication between the cyst and the fetal bladder is a hallmark of patent ductus urachus, which has an estimated incidence of 1-2:100,000 and may be detected prenatally by high-resolution ultrasound (Persutte WH et al. J Ultrasound Med 1988; 7: 399-403; Wildhaber BE et al. Arch Dis Child Fetal Neonatal Ed 2005; 90: F535-536). We present a case of a patent ductus urachus initially presenting as an allantoic cord cyst followed by edematous swelling of the umbilical cord.
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引用次数: 3
Editorial. 社论。
IF 3.2 Q2 Medicine Pub Date : 2018-09-01 Epub Date: 2018-10-17 DOI: 10.1055/a-0731-5989
Sonila Pashaj
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引用次数: 0
Atherosclerotic Lesions in the Superficial Femoral Artery (SFA) Characterized with Velocity Ratios using Vector Velocity Ultrasound. 用矢量速度超声速度比表征股浅动脉(SFA)粥样硬化病变。
IF 3.2 Q2 Medicine Pub Date : 2018-09-01 Epub Date: 2018-09-18 DOI: 10.1055/a-0637-2437
Peter Møller Hansen, Kristoffer Lindskov Hansen, Mads Møller Pedersen, Theis Lange, Lars Lönn, Jørgen Arendt Jensen, Michael Bachmann Nielsen

Purpose: Atherosclerotic arteries are challenging to evaluate quantitatively using spectral Doppler ultrasound because of the turbulent flow conditions that occur in relation to the atherosclerotic stenoses. Vector velocity ultrasound is angle independent and provides flow information, which could potentially improve the diagnosis of arterial stenoses. The purpose of the study is to distinguish significant stenoses in the superficial femoral artery (> 50% diameter reduction) from non-significant stenoses based on velocity ratios derived from the commercially available vector velocity ultrasound technique Vector Flow Imaging (VFI).

Materials and methods: Velocity ratios (intrastenotic blood flow velocity divided by pre- or poststenotic velocity) from a total of 16 atherosclerotic stenoses and plaques in the superficial femoral artery of 11 patients were obtained using VFI. The stenosis degree, expressed as percentage diameter reduction of the artery, was determined from digital subtraction angiography and compared to the velocity ratios.

Results: A velocity ratio of 2.5 was found to distinguish clinically relevant stenoses with>50% diameter reduction from clinically non-relevant stenoses with<50% diameter reduction and the difference was statistically significant.

Conclusion: The study indicates that VFI is a potential future tool for the evaluation of arterial stenoses.

目的:由于与动脉粥样硬化性狭窄相关的湍流条件,使用频谱多普勒超声定量评估动脉粥样硬化性动脉是具有挑战性的。矢量速度超声与角度无关,可提供血流信息,有可能提高动脉狭窄的诊断。本研究的目的是根据商业上可用的矢量速度超声技术矢量流成像(VFI)得出的速度比,区分股浅动脉的明显狭窄(> 50%的直径缩小)和非明显狭窄。材料与方法:对11例患者的16例股浅动脉粥样硬化性狭窄和斑块,采用VFI法获得血流速度比(狭窄内血流速度除以狭窄前或狭窄后血流速度)。狭窄程度,以动脉直径缩小百分比表示,由数字减影血管造影确定,并与流速比进行比较。结果:发现2.5的流速比可以区分临床上相关的狭窄和临床上不相关的狭窄。结论:该研究表明VFI是未来评估动脉狭窄的潜在工具。
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引用次数: 1
Evaluation of Peak Reflux Velocities with Vector Flow Imaging and Spectral Doppler Ultrasound in Varicose Veins. 用矢量血流成像和频谱多普勒超声评估静脉曲张的峰值回流速度
IF 3.2 Q2 Medicine Pub Date : 2018-09-01 Epub Date: 2018-09-28 DOI: 10.1055/a-0643-4430
Thor Bechsgaard, Kristoffer Lindskov Hansen, Andreas Brandt, Ramin Moshavegh, Julie Lyng Forman, Pia Føgh, Lotte Klitfod, Niels Bækgaard, Lars Lönn, Jørgen Arendt Jensen, Michael Bachmann Nielsen

Purpose Spectral Doppler ultrasound (SDUS) is used for quantifying reflux in lower extremity varicose veins. The technique is angle-dependent opposed to the new angle-independent Vector Flow Imaging (VFI) method. The aim of this study was to compare peak reflux velocities obtained with VFI and SDUS in patients with chronic venous disease, i. e., pathological retrograde blood flow caused by incompetent venous valves. Materials and Methods 64 patients with chronic venous disease were scanned with VFI and SDUS in the great or the small saphenous vein, and reflux velocities were compared to three assessment tools for chronic venous disease. A flow rig was used to assess the accuracy and precision of the two methods. Results The mean peak reflux velocities differed significantly (VFI: 47.4 cm/s vs. SDUS: 62.0 cm/s, p<0.001). No difference in absolute precision (p=0.18) nor relative precision (p=0.79) was found. No correlation to disease severity, according to assessment tools, was found for peak reflux velocities obtained with either method. In vitro, VFI was more accurate but equally precise when compared to SDUS. Conclusion Both VFI and SDUS detected the pathologic retrograde flow in varicose veins but measured different reflux velocities with equal precision. VFI may play a role in evaluating venous disease in the future.

目的 频谱多普勒超声(SDUS)用于量化下肢静脉曲张的回流。该技术与角度无关,而新的矢量血流成像(VFI)方法与角度无关。本研究的目的是比较 VFI 和 SDUS 在慢性静脉疾病(即静脉瓣膜功能不全导致的病理性血流逆流)患者中获得的峰值回流速度。材料和方法 对 64 名慢性静脉疾病患者的大隐静脉或小隐静脉进行 VFI 和 SDUS 扫描,并将回流速度与慢性静脉疾病的三种评估工具进行比较。使用血流钻机评估两种方法的准确性和精确度。结果 平均峰值回流速度差异显著(VFI:结论 VFI 和 SDUS 都能检测出曲张静脉中的病理性逆流,但测量出的逆流速度不同,精确度相同。VFI 未来可能在评估静脉疾病中发挥作用。
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引用次数: 0
期刊
Ultrasound International Open
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