首页 > 最新文献

Clinical Medicine Insights-Pediatrics最新文献

英文 中文
Neonatal Sepsis and Associated Factors Among Neonates Admitted to Neonatal Intensive Care Unit in General Hospitals, Eastern Ethiopia 2020 埃塞俄比亚东部综合医院新生儿重症监护室新生儿脓毒症及其相关因素
IF 1.5 Q2 PEDIATRICS Pub Date : 2022-01-01 DOI: 10.1177/11795565221098346
Abdurahman Kedir Roble, Liyew Mekonen Ayehubizu, Hafsa Mohamed Olad
Introduction: Globally, the major cause of neonatal mortality and morbidity is neonatal sepsis, which is defined as a clinical course marked by systemic inflammation in the presence of infection in a newborn. There are limited data concerning neonatal sepsis in eastern Ethiopia. As a result, this study aimed to determine the prevalence of neonatal sepsis and associated factors among neonates admitted to intensive care units at general hospitals in Eastern Ethiopia. Methods: A hospital-based cross-sectional study with retrospective document review was conducted among newborns hospitalized in neonatal intensive care units. Using simple random sampling, the charts of 356 newborns who were hospitalized between January and December 2019 were included, and data were collected using a pretested checklist. Data were entered into Epi data version 3.1 and analyzed with SPSS version 22. Results: The overall prevalence of neonatal sepsis was 45.8% (95% CI 40.7, 51.4). Prolonged rupture of the membrane (AOR = 2.38, 95% CI: [1.27-4.45]), vaginal delivery (AOR = 1.78, 95%, CI: [1.09, 2.96]) APGAR score <7 (AOR = 4.55, 95% CI: [2.49-8.29]), prelacteal feeding (AOR = 3.54, 95% CI: [1.68-8.23]), and mechanical ventilation (AOR = 4.97,95%CI: [2.78-8.89]) were predictors associated with neonatal sepsis. Conclusion: In this study, the prevalence of neonatal sepsis was high, and factors associated with neonatal sepsis included prolonged rupture of membrane, mode of delivery, low APGAR score, prelacteal feeding and mechanical ventilation. As a result, maternal and neonatal care should be enhanced to lower the risk of neonatal sepsis.
在全球范围内,新生儿死亡和发病的主要原因是新生儿败血症,它被定义为新生儿感染时全身性炎症的临床过程。关于埃塞俄比亚东部新生儿败血症的数据有限。因此,本研究旨在确定埃塞俄比亚东部综合医院重症监护病房收治的新生儿中新生儿败血症的患病率及其相关因素。方法:对在新生儿重症监护病房住院的新生儿进行以医院为基础的横断面研究和回顾性文献复习。通过简单的随机抽样,纳入了2019年1月至12月期间住院的356名新生儿的图表,并使用预测试的清单收集数据。数据录入Epi数据3.1版,使用SPSS 22版进行分析。结果:新生儿脓毒症的总患病率为45.8% (95% CI 40.7, 51.4)。胎膜破裂时间延长(AOR = 2.38, 95%CI:[1.27 ~ 4.45])、阴道分娩(AOR = 1.78, 95%CI:[1.09 ~ 2.96])、APGAR评分<7 (AOR = 4.55, 95%CI:[2.49 ~ 8.29])、乳前喂养(AOR = 3.54, 95%CI:[1.68 ~ 8.23])、机械通气(AOR = 4.97,95%CI:[2.78 ~ 8.89])是新生儿脓毒症的预测因素。结论:本研究中新生儿脓毒症患病率较高,与新生儿脓毒症相关的因素包括胎膜破裂时间延长、分娩方式、低APGAR评分、乳前喂养、机械通气等。因此,应加强孕产妇和新生儿护理,以降低新生儿败血症的风险。
{"title":"Neonatal Sepsis and Associated Factors Among Neonates Admitted to Neonatal Intensive Care Unit in General Hospitals, Eastern Ethiopia 2020","authors":"Abdurahman Kedir Roble, Liyew Mekonen Ayehubizu, Hafsa Mohamed Olad","doi":"10.1177/11795565221098346","DOIUrl":"https://doi.org/10.1177/11795565221098346","url":null,"abstract":"Introduction: Globally, the major cause of neonatal mortality and morbidity is neonatal sepsis, which is defined as a clinical course marked by systemic inflammation in the presence of infection in a newborn. There are limited data concerning neonatal sepsis in eastern Ethiopia. As a result, this study aimed to determine the prevalence of neonatal sepsis and associated factors among neonates admitted to intensive care units at general hospitals in Eastern Ethiopia. Methods: A hospital-based cross-sectional study with retrospective document review was conducted among newborns hospitalized in neonatal intensive care units. Using simple random sampling, the charts of 356 newborns who were hospitalized between January and December 2019 were included, and data were collected using a pretested checklist. Data were entered into Epi data version 3.1 and analyzed with SPSS version 22. Results: The overall prevalence of neonatal sepsis was 45.8% (95% CI 40.7, 51.4). Prolonged rupture of the membrane (AOR = 2.38, 95% CI: [1.27-4.45]), vaginal delivery (AOR = 1.78, 95%, CI: [1.09, 2.96]) APGAR score <7 (AOR = 4.55, 95% CI: [2.49-8.29]), prelacteal feeding (AOR = 3.54, 95% CI: [1.68-8.23]), and mechanical ventilation (AOR = 4.97,95%CI: [2.78-8.89]) were predictors associated with neonatal sepsis. Conclusion: In this study, the prevalence of neonatal sepsis was high, and factors associated with neonatal sepsis included prolonged rupture of membrane, mode of delivery, low APGAR score, prelacteal feeding and mechanical ventilation. As a result, maternal and neonatal care should be enhanced to lower the risk of neonatal sepsis.","PeriodicalId":45027,"journal":{"name":"Clinical Medicine Insights-Pediatrics","volume":"71 1","pages":""},"PeriodicalIF":1.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85755268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Jejunoileal Atresia in a Newborn: Our Experience From Northern Tanzania and Literature Review 新生儿空肠回肠闭锁:坦桑尼亚北部的经验及文献回顾
IF 1.5 Q2 PEDIATRICS Pub Date : 2022-01-01 DOI: 10.1177/11795565221075313
Gregory Goodluck, Marianne Gnanamuttupulle, A. Sadiq, D. Msuya, Samwel Chugulu, J. Lodhia
Jenunoileal atresia is a congenital defect that causes small bowel obstruction in newborns. They are classified into 5 types and simple abdominal x-ray can aid in the diagnosis and with prompt resuscitation and surgery provides positive outcome. We present a 5-day-old newborn male baby was presented with features of intestinal obstruction since birth. Diagnosis of atresia of the small bowel was made through plain abdominal x-ray and was successfully operated. During the recovery, the baby developed surgical site infection which was managed promptly.
肠回肠闭锁是一种先天性缺陷,可引起新生儿小肠阻塞。它们被分为5种类型,简单的腹部x线可以帮助诊断,及时复苏和手术提供积极的结果。我们提出了一个5天大的新生男婴,自出生以来就表现出肠梗阻的特征。通过腹部平片诊断小肠闭锁并成功手术。在恢复过程中,婴儿出现手术部位感染,并及时处理。
{"title":"Jejunoileal Atresia in a Newborn: Our Experience From Northern Tanzania and Literature Review","authors":"Gregory Goodluck, Marianne Gnanamuttupulle, A. Sadiq, D. Msuya, Samwel Chugulu, J. Lodhia","doi":"10.1177/11795565221075313","DOIUrl":"https://doi.org/10.1177/11795565221075313","url":null,"abstract":"Jenunoileal atresia is a congenital defect that causes small bowel obstruction in newborns. They are classified into 5 types and simple abdominal x-ray can aid in the diagnosis and with prompt resuscitation and surgery provides positive outcome. We present a 5-day-old newborn male baby was presented with features of intestinal obstruction since birth. Diagnosis of atresia of the small bowel was made through plain abdominal x-ray and was successfully operated. During the recovery, the baby developed surgical site infection which was managed promptly.","PeriodicalId":45027,"journal":{"name":"Clinical Medicine Insights-Pediatrics","volume":"18 3 1","pages":""},"PeriodicalIF":1.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90409523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anthropometric Criteria for Identifying Infants Under 6 Months of Age at Risk of Morbidity and Mortality: A Systematic Review. 识别6岁以下婴儿的人体测量标准 发病率和死亡率风险的月龄:一项系统综述。
IF 1.5 Q2 PEDIATRICS Pub Date : 2021-10-21 eCollection Date: 2021-01-01 DOI: 10.1177/11795565211049904
Christoph Hoehn, Natasha Lelijveld, Martha Mwangome, James A Berkley, Marie McGrath, Marko Kerac

Background: There is increasing global focus on small and nutritionally at-risk infants aged <6 months (<6 m). Current WHO guidelines recommend weight-for-length z-score (WLZ) for enrolment to malnutrition treatment programmes but acknowledge a weak evidence-base. This review aims to inform future guidelines by examining which anthropometric criteria best identify infants <6 m at high risk of mortality/morbidity.

Methods: We searched Medline, EMBASE, CINAHL, Global Health, Cochrane Library and POPLINE for studies conducted in low- and middle-income countries and published between 1990 and October 2020. We included studies reporting anthropometric assessment of nutritional status in infants <6 m and assessed the association with subsequent morbidity or mortality.

Results: A total of 19 studies were included in the final review, covering 20 countries, predominantly in sub-Saharan Africa. WLZ had poor reliability and poor prognostic ability to identify infants at risk of death. Mid-upper arm circumference (MUAC) and weight-for-age z-score (WAZ) were better at identifying infants at risk of mortality/morbidity. MUAC-for-age z-score did not perform better than using a single MUAC cut-off. Suggested MUAC cut-offs for this age group varied by context, ranging from 10.5 to 11.5 cm. The assessment for reliability showed that length was difficult to measure, making WLZ the least reliable indicator overall.

Conclusion: Evidence from our review suggests that a change in current practice is necessary. To better identify small and nutritionally at-risk infants <6 m WAZ and/or MUAC rather than WLZ should be used. Future research should explore possible benefits for programme coverage, impact and cost-effectiveness. Research should also examine if context-specific MUAC thresholds are needed.

背景:全球越来越关注营养不良治疗计划中的z评分(WLZ)小婴儿和营养风险婴儿,但承认证据基础薄弱。这篇综述旨在通过检查哪些人体测量标准最能识别婴儿来为未来的指导方针提供信息。方法:我们搜索了Medline、EMBASE、CINAHL、Global Health、Cochrane Library和POPLINE,寻找1990年至2020年10月在中低收入国家进行的研究。我们纳入了报告婴儿营养状况人体测量评估的研究。结果:最终审查共纳入19项研究,涵盖20个国家,主要位于撒哈拉以南非洲。WLZ在识别有死亡风险的婴儿方面的可靠性和预后能力较差。上臂中围(MUAC)和年龄加权z评分(WAZ)更能识别有死亡/发病风险的婴儿。年龄z评分的MUAC并不比使用单个MUAC截止值表现得更好。该年龄组建议的MUAC截止值因环境而异,从10.5到11.5不等 对可靠性的评估表明,长度很难测量,使WLZ成为总体上最不可靠的指标。结论:我们审查的证据表明,有必要改变目前的做法。更好地识别小婴儿和营养风险婴儿
{"title":"Anthropometric Criteria for Identifying Infants Under 6 Months of Age at Risk of Morbidity and Mortality: A Systematic Review.","authors":"Christoph Hoehn,&nbsp;Natasha Lelijveld,&nbsp;Martha Mwangome,&nbsp;James A Berkley,&nbsp;Marie McGrath,&nbsp;Marko Kerac","doi":"10.1177/11795565211049904","DOIUrl":"10.1177/11795565211049904","url":null,"abstract":"<p><strong>Background: </strong>There is increasing global focus on small and nutritionally at-risk infants aged <6 months (<6 m). Current WHO guidelines recommend weight-for-length <i>z</i>-score (WLZ) for enrolment to malnutrition treatment programmes but acknowledge a weak evidence-base. This review aims to inform future guidelines by examining which anthropometric criteria best identify infants <6 m at high risk of mortality/morbidity.</p><p><strong>Methods: </strong>We searched Medline, EMBASE, CINAHL, Global Health, Cochrane Library and POPLINE for studies conducted in low- and middle-income countries and published between 1990 and October 2020. We included studies reporting anthropometric assessment of nutritional status in infants <6 m and assessed the association with subsequent morbidity or mortality.</p><p><strong>Results: </strong>A total of 19 studies were included in the final review, covering 20 countries, predominantly in sub-Saharan Africa. WLZ had poor reliability and poor prognostic ability to identify infants at risk of death. Mid-upper arm circumference (MUAC) and weight-for-age <i>z</i>-score (WAZ) were better at identifying infants at risk of mortality/morbidity. MUAC-for-age <i>z</i>-score did not perform better than using a single MUAC cut-off. Suggested MUAC cut-offs for this age group varied by context, ranging from 10.5 to 11.5 cm. The assessment for reliability showed that length was difficult to measure, making WLZ the least reliable indicator overall.</p><p><strong>Conclusion: </strong>Evidence from our review suggests that a change in current practice is necessary. To better identify small and nutritionally at-risk infants <6 m WAZ and/or MUAC rather than WLZ should be used. Future research should explore possible benefits for programme coverage, impact and cost-effectiveness. Research should also examine if context-specific MUAC thresholds are needed.</p>","PeriodicalId":45027,"journal":{"name":"Clinical Medicine Insights-Pediatrics","volume":"15 ","pages":"11795565211049904"},"PeriodicalIF":1.5,"publicationDate":"2021-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543668/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10664948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Voiding Disorders in Pediatrician's Practice. 儿科医生实践中的排尿障碍。
IF 1.5 Q2 PEDIATRICS Pub Date : 2020-11-27 eCollection Date: 2020-01-01 DOI: 10.1177/1179556520975035
Magda Rakowska-Silska, Katarzyna Jobs, Aleksandra Paturej, Bolesław Kalicki

Voiding disorders result usually from functional disturbance. However, relevant organic diseases must be excluded prior to diagnosis of functional disorders. Additional tests, such as urinalysis or abdominal ultrasound are required. Further diagnostics is necessary in the presence of alarm symptoms, such as secondary nocturnal enuresis, weak or intermittent urine flow, systemic symptoms, glucosuria, proteinuria, leukocyturia, erythrocyturia, skin lesions in the lumbar region, altered sensations in the perineum. Functional micturition disorders were thoroughly described in 2006, and revised in 2015 by ICCS (International Children's Continence Society) and are divided into storage symptoms (increased and decreased voiding frequency, incontinence, urgency, nocturia), voiding symptoms hesitancy, straining, weak stream, intermittency, dysuria), and symptoms that cannot be assigned to any of the above groups (voiding postponement, holding maneuvers, feeling of incomplete emptying, urinary retention, post micturition dribble, spraying of the urinary stream). Functional voiding disorders are frequently associated with constipation. Bladder and bowel dysfunction (BBD) is diagnosed when lower urinary tract symptoms are accompanied by problems with defecation. Monosymptomatic enuresis is the most common voiding disorder encountered by pediatricians. It is diagnosed in children older than 5 years without any other lower urinary tract symptoms. Other types of voiding disorders such as: non-monosymptomatic enuresis, overactive and underactive bladder, voiding postponement, bladder outlet obstruction, stress or giggle incontinence, urethrovaginal reflux usually require specialized diagnostics and therapy. Treatment of all types of functional voiding disorders is based on non-pharmacological recommendations (urotherapy), and such education should be implemented by primary care pediatricians.

排尿障碍通常由功能障碍引起。然而,在诊断功能障碍之前,必须排除相关的器质性疾病。需要进行额外的检查,如尿液分析或腹部超声检查。如果出现警示症状,如继发性夜间遗尿、微弱或间歇性尿流、全身症状、血糖、蛋白尿、白细胞尿、红细胞尿、腰部皮肤病变、会阴部感觉改变等,则需要进一步诊断。排尿功能障碍是彻底的描述,2006年修订后的2015年,可以(国际儿童自制协会)和症状分为存储(增加和减少排尿的频率,尿失禁,紧迫感,夜尿症),排尿症状犹豫,紧张,弱流,间歇性,排尿困难),症状不能分配给任何上述团体(排泄推迟,举行演习,排空的感觉,尿潴留,排尿后滴、喷的尿流)。功能性排尿障碍常与便秘有关。当下尿路症状伴有排便问题时,诊断为膀胱和肠道功能障碍(BBD)。单症状性遗尿是儿科医生遇到的最常见的排尿障碍。5岁以上儿童无其他下尿路症状。其他类型的排尿障碍,如:非单症状性遗尿、膀胱过度活跃和不活跃、排尿延迟、膀胱出口阻塞、压力或咯咯声失禁、尿道阴道反流等,通常需要专门的诊断和治疗。所有类型的功能性排尿障碍的治疗都是基于非药物建议(泌尿治疗),这样的教育应该由初级保健儿科医生实施。
{"title":"Voiding Disorders in Pediatrician's Practice.","authors":"Magda Rakowska-Silska,&nbsp;Katarzyna Jobs,&nbsp;Aleksandra Paturej,&nbsp;Bolesław Kalicki","doi":"10.1177/1179556520975035","DOIUrl":"https://doi.org/10.1177/1179556520975035","url":null,"abstract":"<p><p>Voiding disorders result usually from functional disturbance. However, relevant organic diseases must be excluded prior to diagnosis of functional disorders. Additional tests, such as urinalysis or abdominal ultrasound are required. Further diagnostics is necessary in the presence of alarm symptoms, such as secondary nocturnal enuresis, weak or intermittent urine flow, systemic symptoms, glucosuria, proteinuria, leukocyturia, erythrocyturia, skin lesions in the lumbar region, altered sensations in the perineum. Functional micturition disorders were thoroughly described in 2006, and revised in 2015 by ICCS (International Children's Continence Society) and are divided into storage symptoms (increased and decreased voiding frequency, incontinence, urgency, nocturia), voiding symptoms hesitancy, straining, weak stream, intermittency, dysuria), and symptoms that cannot be assigned to any of the above groups (voiding postponement, holding maneuvers, feeling of incomplete emptying, urinary retention, post micturition dribble, spraying of the urinary stream). Functional voiding disorders are frequently associated with constipation. Bladder and bowel dysfunction (BBD) is diagnosed when lower urinary tract symptoms are accompanied by problems with defecation. Monosymptomatic enuresis is the most common voiding disorder encountered by pediatricians. It is diagnosed in children older than 5 years without any other lower urinary tract symptoms. Other types of voiding disorders such as: non-monosymptomatic enuresis, overactive and underactive bladder, voiding postponement, bladder outlet obstruction, stress or giggle incontinence, urethrovaginal reflux usually require specialized diagnostics and therapy. Treatment of all types of functional voiding disorders is based on non-pharmacological recommendations (urotherapy), and such education should be implemented by primary care pediatricians.</p>","PeriodicalId":45027,"journal":{"name":"Clinical Medicine Insights-Pediatrics","volume":"14 ","pages":"1179556520975035"},"PeriodicalIF":1.5,"publicationDate":"2020-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1179556520975035","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38350917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Laboratory abnormalities in children with novel Coronavirus Disease 2019. 2019年新型冠状病毒病儿童的实验室异常
IF 1.5 Q2 PEDIATRICS Pub Date : 2020-09-11 eCollection Date: 2020-01-01 DOI: 10.1177/1179556520955177
Laila Bourkhissi, Karima El Fakiri, Houda Nassih, Rabiy El Qadiry, Aicha Bourrahouat, Imane Ait Sab, Noureddine Rada, Ghizlane Draiss, Mohammed Bouskraoui

The novel Coronavirus disease 2019 continues to be a worldwide pandemic. Yet, little is still known about the biological features of this emergent infection in children. In this prospective study, we collected 68 children infected with SARS-COV-2 from March 2020 to May 2020, in Marrakesh, Morocco. No severe cases were observed in this cohort, and 66% of the patients were asymptomatic. The main laboratory abnormalities were hematological, as we found Leucopoenia in 4.4% of the cases, hyperleukocytosis in 1.6%. Neutropenia was found in 5 patients (7%) and only 2 cases (3%) had Lymphopenia. The inflammation and coagulation biomarkers were normal in the majority of the cases, as for liver and kidney function. Lactate dehydrogenase (LDH) serum levels were elevated in 8 cases (11.67%). The COVID-19 in children seems to have mild course and better outcome than in adults, which impacts the laboratory findings in this category. More studies must be conducted to learn more about the laboratory abnormalities in pediatric COVID-19.

2019年新型冠状病毒病继续成为全球大流行。然而,对这种儿童突发感染的生物学特征仍然知之甚少。在这项前瞻性研究中,我们收集了2020年3月至2020年5月在摩洛哥马拉喀什感染SARS-COV-2的68名儿童。在该队列中未观察到严重病例,66%的患者无症状。主要的实验室异常为血液学异常,我们发现白细胞减少率为4.4%,白细胞增多率为1.6%。中性粒细胞减少5例(7%),淋巴细胞减少2例(3%)。大多数病例的炎症和凝血生物标志物正常,肝肾功能正常。血清乳酸脱氢酶升高8例(11.67%)。与成人相比,儿童中的COVID-19似乎病程较轻,预后较好,这影响了这一类别的实验室结果。必须进行更多的研究,以更多地了解儿童COVID-19的实验室异常情况。
{"title":"Laboratory abnormalities in children with novel Coronavirus Disease 2019.","authors":"Laila Bourkhissi, Karima El Fakiri, Houda Nassih, Rabiy El Qadiry, Aicha Bourrahouat, Imane Ait Sab, Noureddine Rada, Ghizlane Draiss, Mohammed Bouskraoui","doi":"10.1177/1179556520955177","DOIUrl":"10.1177/1179556520955177","url":null,"abstract":"<p><p>The novel Coronavirus disease 2019 continues to be a worldwide pandemic. Yet, little is still known about the biological features of this emergent infection in children. In this prospective study, we collected 68 children infected with SARS-COV-2 from March 2020 to May 2020, in Marrakesh, Morocco. No severe cases were observed in this cohort, and 66% of the patients were asymptomatic. The main laboratory abnormalities were hematological, as we found Leucopoenia in 4.4% of the cases, hyperleukocytosis in 1.6%. Neutropenia was found in 5 patients (7%) and only 2 cases (3%) had Lymphopenia. The inflammation and coagulation biomarkers were normal in the majority of the cases, as for liver and kidney function. Lactate dehydrogenase (LDH) serum levels were elevated in 8 cases (11.67%). The COVID-19 in children seems to have mild course and better outcome than in adults, which impacts the laboratory findings in this category. More studies must be conducted to learn more about the laboratory abnormalities in pediatric COVID-19.</p>","PeriodicalId":45027,"journal":{"name":"Clinical Medicine Insights-Pediatrics","volume":"14 ","pages":"1179556520955177"},"PeriodicalIF":1.5,"publicationDate":"2020-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1179556520955177","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38407105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
Childhood Obesity: Is the Built Environment More Important Than the Food Environment? 儿童肥胖:建筑环境比食物环境更重要吗?
IF 1.5 Q2 PEDIATRICS Pub Date : 2020-07-31 eCollection Date: 2020-01-01 DOI: 10.1177/1179556520932123
Wenes Pereira Reis, Mark Ghamsary, Caroline Galustian, Henrik Galust, Patti Herring, Josileide Gaio, Hildemar Dos Santos

Obesity continues to be a health burden to society and new efforts may be needed to combat this epidemic. This study aims to investigate the contribution of parents education and level of income, food environment (grocery stores and fast food restaurants), and built environment (perceived safety, availability/quantity of parks) on childhood obesity. This cross-sectional observational study explored whether parents education and income level, built environment, and food environment can affect children with obesity. Participants were selected from 3 separate elementary schools located in an urban community with higher risk to have children with obesity in Montclair, California. Children living in families with low incomes have 2.31 times greater odds to be affected by obesity than children living in higher income homes. Children whose parents did not feel safe in their neighborhoods had odds of obesity 2.23 times greater than those who reported their neighborhoods as safe. Age also appeared to be a risk factor, and the odds of children affected by obesity among children 8 to 9 years was 0.79, and the odds of being affected by obesity among children 10 to 11 years of age was 0.36, when compared to children 6 to 7 years old. Findings suggest that low family income, perceptions of neighborhoods as unsafe, and young age are associated with higher body mass index (BMI) percentiles among children living in poor neighborhoods in Montclair, California.

肥胖仍然是社会的健康负担,可能需要采取新的措施来防治这一流行病。本研究旨在探讨父母教育程度、收入水平、食物环境(杂货店和快餐店)、建筑环境(感知安全、公园的可用性/数量)对儿童肥胖的影响。本横断面观察研究探讨父母教育程度、收入水平、建筑环境和食物环境是否会影响儿童肥胖。参与者是从位于加州蒙特克莱尔市一个城市社区的三所不同的小学中挑选出来的,这些社区的儿童肥胖的风险较高。低收入家庭的儿童患肥胖症的几率是高收入家庭儿童的2.31倍。父母在社区中感到不安全的孩子肥胖的几率是那些认为社区安全的孩子的2.23倍。年龄似乎也是一个风险因素,与6至7岁的儿童相比,8至9岁儿童患肥胖症的几率为0.79,10至11岁儿童患肥胖症的几率为0.36。研究结果表明,生活在加州蒙特克莱尔贫困社区的儿童中,家庭收入低、认为社区不安全以及年龄小与较高的身体质量指数(BMI)百分位数有关。
{"title":"Childhood Obesity: Is the Built Environment More Important Than the Food Environment?","authors":"Wenes Pereira Reis,&nbsp;Mark Ghamsary,&nbsp;Caroline Galustian,&nbsp;Henrik Galust,&nbsp;Patti Herring,&nbsp;Josileide Gaio,&nbsp;Hildemar Dos Santos","doi":"10.1177/1179556520932123","DOIUrl":"https://doi.org/10.1177/1179556520932123","url":null,"abstract":"<p><p>Obesity continues to be a health burden to society and new efforts may be needed to combat this epidemic. This study aims to investigate the contribution of parents education and level of income, food environment (grocery stores and fast food restaurants), and built environment (perceived safety, availability/quantity of parks) on childhood obesity. This cross-sectional observational study explored whether parents education and income level, built environment, and food environment can affect children with obesity. Participants were selected from 3 separate elementary schools located in an urban community with higher risk to have children with obesity in Montclair, California. Children living in families with low incomes have 2.31 times greater odds to be affected by obesity than children living in higher income homes. Children whose parents did not feel safe in their neighborhoods had odds of obesity 2.23 times greater than those who reported their neighborhoods as safe. Age also appeared to be a risk factor, and the odds of children affected by obesity among children 8 to 9 years was 0.79, and the odds of being affected by obesity among children 10 to 11 years of age was 0.36, when compared to children 6 to 7 years old. Findings suggest that low family income, perceptions of neighborhoods as unsafe, and young age are associated with higher body mass index (BMI) percentiles among children living in poor neighborhoods in Montclair, California.</p>","PeriodicalId":45027,"journal":{"name":"Clinical Medicine Insights-Pediatrics","volume":"14 ","pages":"1179556520932123"},"PeriodicalIF":1.5,"publicationDate":"2020-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1179556520932123","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38403315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Pre-schoolers Referred to a Child and Adolescent Mental Health Clinic: A Hospital Quality Improvement Report. 儿童和青少年心理健康诊所转诊的学龄前儿童:医院质量改进报告》。
IF 1.7 Q2 PEDIATRICS Pub Date : 2020-07-02 eCollection Date: 2020-01-01 DOI: 10.1177/1179556520925479
Irene B Elgen, Mariell Stikholmen, Rolf Gjestad, Inger Lande Danielsen, Silje Fevang

Objective: Aim of the study was to evaluate the patient pathway from referral to assessment and diagnosis of pre-schoolers referred to a Child and Adolescent Mental Health Clinic (CAMHC) in Norway.

Method: Following data were collected retrospectively from medical records over a 2-year study period: data from clinical interviews for diagnostic evaluation, observation findings in kindergartens and the CAMHC, and results from medical examinations. The times taken from referral to first contact with the CAMHC, then to the first evaluation, and finally to diagnosis were assessed.

Results: Of 13 402 pre-schoolers, 88 (0.7%) were referred to the CAMHC, of which 15 refused assessment and 69 completed a diagnostic assessment. Of the assessed children, 15 (21%) did not meet any criteria for an International Classification of Diseases, Tenth revision (ICD-10) diagnosis, 26 (38%) were diagnosed with developmental disorders, and 10 (14%) were given a non-specific diagnosis. For those children without a specific diagnosis, the mean time taken from referral to CAMHC assessment and diagnosis was longer, although not statistically significant, compared with those with a specific diagnosis (P = .52). No significant correlation between referral symptoms and final diagnosis was found.

Conclusions: Pre-schoolers referred to the CAMHC have an increased risk of having developmental disorders. Furthermore, 1 in 5 of the children had comorbidities. We propose more effective health care service by developing an interdisciplinary approach for the management of these children.

研究目的本研究旨在评估挪威儿童和青少年心理健康诊所(CAMHC)转诊的学龄前儿童从转诊到评估和诊断的过程:在为期两年的研究期间,我们从医疗记录中回顾性地收集了以下数据:诊断评估的临床访谈数据、在幼儿园和儿童与青少年心理健康诊所的观察结果以及体检结果。研究评估了从转介到首次接触儿童保健中心,再到首次评估,最后到确诊所花费的时间:在 13 402 名学龄前儿童中,有 88 人(0.7%)被转介到儿童保健中心,其中 15 人拒绝接受评估,69 人完成了诊断评估。在接受评估的儿童中,15 名儿童(21%)不符合《国际疾病分类》第十版(ICD-10)的任何诊断标准,26 名儿童(38%)被诊断为发育障碍,10 名儿童(14%)被诊断为非特异性诊断。与有具体诊断的儿童相比,没有具体诊断的儿童从转介到儿童保健中心评估和诊断所需的平均时间更长,但没有统计学意义(P = .52)。转介症状与最终诊断之间没有发现明显的相关性:结论:转诊至儿童心理健康中心的学龄前儿童患有发育障碍的风险增加。此外,五分之一的儿童患有合并症。我们建议通过发展跨学科方法来管理这些儿童,从而提供更有效的医疗保健服务。
{"title":"Pre-schoolers Referred to a Child and Adolescent Mental Health Clinic: A Hospital Quality Improvement Report.","authors":"Irene B Elgen, Mariell Stikholmen, Rolf Gjestad, Inger Lande Danielsen, Silje Fevang","doi":"10.1177/1179556520925479","DOIUrl":"10.1177/1179556520925479","url":null,"abstract":"<p><strong>Objective: </strong>Aim of the study was to evaluate the patient pathway from referral to assessment and diagnosis of pre-schoolers referred to a Child and Adolescent Mental Health Clinic (CAMHC) in Norway.</p><p><strong>Method: </strong>Following data were collected retrospectively from medical records over a 2-year study period: data from clinical interviews for diagnostic evaluation, observation findings in kindergartens and the CAMHC, and results from medical examinations. The times taken from referral to first contact with the CAMHC, then to the first evaluation, and finally to diagnosis were assessed.</p><p><strong>Results: </strong>Of 13 402 pre-schoolers, 88 (0.7%) were referred to the CAMHC, of which 15 refused assessment and 69 completed a diagnostic assessment. Of the assessed children, 15 (21%) did not meet any criteria for an <i>International Classification of Diseases, Tenth revision</i> (<i>ICD-10</i>) diagnosis, 26 (38%) were diagnosed with developmental disorders, and 10 (14%) were given a non-specific diagnosis. For those children without a specific diagnosis, the mean time taken from referral to CAMHC assessment and diagnosis was longer, although not statistically significant, compared with those with a specific diagnosis (<i>P</i> = .52). No significant correlation between referral symptoms and final diagnosis was found.</p><p><strong>Conclusions: </strong>Pre-schoolers referred to the CAMHC have an increased risk of having developmental disorders. Furthermore, 1 in 5 of the children had comorbidities. We propose more effective health care service by developing an interdisciplinary approach for the management of these children.</p>","PeriodicalId":45027,"journal":{"name":"Clinical Medicine Insights-Pediatrics","volume":"14 ","pages":"1179556520925479"},"PeriodicalIF":1.7,"publicationDate":"2020-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/97/70/10.1177_1179556520925479.PMC7333487.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38151166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Formative Process Evaluation of the "Connect" Physical Activity Feasibility Trial for Adolescents. 青少年“连接”体育活动可行性试验的形成过程评价。
IF 1.5 Q2 PEDIATRICS Pub Date : 2020-06-03 eCollection Date: 2020-01-01 DOI: 10.1177/1179556520918902
Nicole Zarrett, Michelle Abraczinskas, Brittany S Cook, Dawn Wilson, Alex Roberts

Most interventions do not reach full implementation in real-world settings. Due to this issue, formative process evaluation during pilot programs can be especially useful to understand implementation strengths and areas for improvement so that full implementation can be reached in future iterations. This study demonstrated how a formative process evaluation of the Connect through Positive Leisure Activities for Youth (Connect) pilot informed course corrections for year 2 implementation. Connect is an intervention to promote a positive social motivational climate for physical activity (PA) in pre-existing after school programs. Connect ran 3 days a week for 8 weeks and had 2 components: a 30-minute "Get-to-Know-You" (GTKY) session and a 60-minute PA session. Formative evaluation was assessed using an observational tool and staff surveys. Changes in youth PA during program hours was assessed as a process outcome using the System for Observing Children's Activity and Relationships during Play (SOCARP). All Connect essential elements were assessed with the observational tool including (a) social goal-oriented support; (b) collaborative, cooperative play; (c) equal treatment/access; and (d) an inclusive and engaging climate. Adequate dose was achieved on all items in all sessions. Although GTKY and PA sessions both reached high fidelity in promoting equal treatment and access, success in reaching fidelity varied for the 3 remaining essential elements. Post-intervention staff surveys indicated acceptability/adoptability of the Connect program and SOCARP observations indicated significant increases in PA from baseline to post-intervention. Changes for year 2 implementation based on the findings are discussed.

大多数干预措施在现实环境中没有得到充分实施。由于这个问题,在试验计划期间的形成性过程评估对于理解实现的优势和需要改进的领域特别有用,这样在未来的迭代中就可以达到完全的实现。本研究展示了“通过积极的青年休闲活动连接”(Connect)试点项目的形成过程评估如何为第二年实施的课程修正提供信息。Connect是一项干预措施,旨在促进已有的课后项目中体育活动(PA)的积极社会动机氛围。Connect每周运行3天,持续8周,有两个部分:30分钟的“了解你”(Get-to-Know-You, GTKY)环节和60分钟的PA环节。形成性评价采用观察工具和员工调查进行评估。使用观察儿童在游戏中的活动和关系系统(SOCARP)来评估青少年在项目时间内PA的变化作为过程结果。所有Connect的基本要素都用观察工具进行了评估,包括(a)社会目标导向的支持;(b)协作性、合作性游戏;(c)平等待遇/机会;(d)包容和吸引人的气候。在所有会议中,所有项目都达到了足够的剂量。尽管GTKY和PA会议在促进平等待遇和机会方面都达到了很高的保真度,但在实现保真度方面,其余三个基本要素的成功程度各不相同。干预后的工作人员调查表明,Connect计划的可接受性和可采用性,SOCARP观察表明,从基线到干预后,PA显著增加。根据调查结果讨论了第2年实施的变化。
{"title":"Formative Process Evaluation of the \"Connect\" Physical Activity Feasibility Trial for Adolescents.","authors":"Nicole Zarrett,&nbsp;Michelle Abraczinskas,&nbsp;Brittany S Cook,&nbsp;Dawn Wilson,&nbsp;Alex Roberts","doi":"10.1177/1179556520918902","DOIUrl":"https://doi.org/10.1177/1179556520918902","url":null,"abstract":"<p><p>Most interventions do not reach full implementation in real-world settings. Due to this issue, formative process evaluation during pilot programs can be especially useful to understand implementation strengths and areas for improvement so that full implementation can be reached in future iterations. This study demonstrated how a formative process evaluation of the Connect through Positive Leisure Activities for Youth (Connect) pilot informed course corrections for year 2 implementation. Connect is an intervention to promote a positive social motivational climate for physical activity (PA) in pre-existing after school programs. Connect ran 3 days a week for 8 weeks and had 2 components: a 30-minute \"Get-to-Know-You\" (GTKY) session and a 60-minute PA session. Formative evaluation was assessed using an observational tool and staff surveys. Changes in youth PA during program hours was assessed as a process outcome using the System for Observing Children's Activity and Relationships during Play (SOCARP). All Connect essential elements were assessed with the observational tool including (a) social goal-oriented support; (b) collaborative, cooperative play; (c) equal treatment/access; and (d) an inclusive and engaging climate. Adequate dose was achieved on all items in all sessions. Although GTKY and PA sessions both reached high fidelity in promoting equal treatment and access, success in reaching fidelity varied for the 3 remaining essential elements. Post-intervention staff surveys indicated acceptability/adoptability of the Connect program and SOCARP observations indicated significant increases in PA from baseline to post-intervention. Changes for year 2 implementation based on the findings are discussed.</p>","PeriodicalId":45027,"journal":{"name":"Clinical Medicine Insights-Pediatrics","volume":"14 ","pages":"1179556520918902"},"PeriodicalIF":1.5,"publicationDate":"2020-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1179556520918902","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38056351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Saving Costs for Hospitals Through Medical Clowning: A Study of Hospital Staff Perspectives on the Impact of the Medical Clown. 通过医疗小丑为医院节省成本:医院员工对医疗小丑影响的看法研究。
IF 1.5 Q2 PEDIATRICS Pub Date : 2020-03-06 eCollection Date: 2020-01-01 DOI: 10.1177/1179556520909376
Jack Gomberg, Amnon Raviv, Eyal Fenig, Noam Meiri

This study explores the perspectives of doctors, nurses, and technicians on the medical clown. A total of 35 subjects were interviewed one on one. Interviews were transcribed and analyzed for common themes. Medical staff outlined novel limitations and views of future directions for the field of medical clowning. Most importantly, many previously unpublished benefits of medical clowns were described. These reported benefits included cost-saving measures for the hospital, increases in staff efficiency, better patient outcomes, and lower stress in medical staff. Given that most of the limitations on medical clowning are financial in nature, these findings have substantial implications for the future of the field. As medical clowning continues to grow, this study outlines the potential for various future research projects within this field of study.

本研究探讨了医生、护士和技术人员对医疗小丑的看法。共对35名受试者进行了一对一的访谈。采访记录和分析共同的主题。医务人员概述了医疗小丑领域的新局限性和未来方向的观点。最重要的是,医学小丑的许多先前未发表的好处被描述。这些报告的好处包括为医院节省了成本、提高了工作人员的效率、改善了病人的治疗效果以及减轻了医务人员的压力。鉴于医疗小丑的大多数限制本质上是经济上的,这些发现对该领域的未来具有重大意义。随着医学小丑的持续增长,这项研究概述了在这一研究领域内各种未来研究项目的潜力。
{"title":"Saving Costs for Hospitals Through Medical Clowning: A Study of Hospital Staff Perspectives on the Impact of the Medical Clown.","authors":"Jack Gomberg,&nbsp;Amnon Raviv,&nbsp;Eyal Fenig,&nbsp;Noam Meiri","doi":"10.1177/1179556520909376","DOIUrl":"https://doi.org/10.1177/1179556520909376","url":null,"abstract":"<p><p>This study explores the perspectives of doctors, nurses, and technicians on the medical clown. A total of 35 subjects were interviewed one on one. Interviews were transcribed and analyzed for common themes. Medical staff outlined novel limitations and views of future directions for the field of medical clowning. Most importantly, many previously unpublished benefits of medical clowns were described. These reported benefits included cost-saving measures for the hospital, increases in staff efficiency, better patient outcomes, and lower stress in medical staff. Given that most of the limitations on medical clowning are financial in nature, these findings have substantial implications for the future of the field. As medical clowning continues to grow, this study outlines the potential for various future research projects within this field of study.</p>","PeriodicalId":45027,"journal":{"name":"Clinical Medicine Insights-Pediatrics","volume":"14 ","pages":"1179556520909376"},"PeriodicalIF":1.5,"publicationDate":"2020-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1179556520909376","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37773172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Hydrocortisone Improves Oxygenation Index and Systolic Blood Pressure in Term Infants With Persistent Pulmonary Hypertension. 氢化可的松改善患有持续性肺动脉高压的足月婴儿的氧合指数和收缩压。
IF 1.5 Q2 PEDIATRICS Pub Date : 2019-11-21 eCollection Date: 2019-01-01 DOI: 10.1177/1179556519888918
Mahdi Alsaleem, Aysha Malik, Satyan Lakshminrusimha, Vasantha Hs Kumar

Persistent pulmonary hypertension of the newborn (PPHN) is an essential cause for hypoxic respiratory failure with significant morbidity and mortality in term and near-term neonates. Hydrocortisone has been shown to decrease oxygen dependency and pulmonary hypertension in neonates with meconium aspiration syndrome and animal studies, respectively. We hypothesize that hydrocortisone will improve oxygenation in term and near-term infants with pulmonary hypertension. We performed a retrospective chart review of all infant with PPHN who received intravenous hydrocortisone therapy as a rescue for severe PPHN. Clinical response was objectively measured using, oxygenation index (OI), PaO2/FiO2 ratio, and inotrope score before, during, and after the hydrocortisone course. We found that hydrocortisone administration resulted in significant improvement of systolic blood pressure, OI, and PaO2/FiO2. In conclusion, hydrocortisone increased systolic blood pressure and improved oxygenation in term and near-term infants with persistent pulmonary hypertension. Prospective randomized trials are required to evaluate these findings further.

新生儿持续性肺动脉高压(PPHN)是缺氧性呼吸衰竭的重要原因,在足月和近期新生儿中具有显著的发病率和死亡率。动物研究表明,氢化可的松可分别降低胎粪吸入综合征新生儿的氧依赖性和肺动脉高压。我们假设氢化可的松可以改善患有肺动脉高压的足月和近期婴儿的氧合。我们对所有接受静脉注射氢化可的松治疗的PPHN婴儿进行了回顾性图表回顾。在氢化可的松疗程之前、期间和之后,使用氧合指数(OI)、PaO2/FiO2比率和inotrope评分客观地测量临床反应。我们发现氢化可的松给药可显著改善收缩压、OI和PaO2/FiO2。总之,氢化可的松可提高患有持续性肺动脉高压的足月和近期婴儿的收缩压并改善氧合。需要进行前瞻性随机试验来进一步评估这些发现。
{"title":"Hydrocortisone Improves Oxygenation Index and Systolic Blood Pressure in Term Infants With Persistent Pulmonary Hypertension.","authors":"Mahdi Alsaleem,&nbsp;Aysha Malik,&nbsp;Satyan Lakshminrusimha,&nbsp;Vasantha Hs Kumar","doi":"10.1177/1179556519888918","DOIUrl":"https://doi.org/10.1177/1179556519888918","url":null,"abstract":"<p><p>Persistent pulmonary hypertension of the newborn (PPHN) is an essential cause for hypoxic respiratory failure with significant morbidity and mortality in term and near-term neonates. Hydrocortisone has been shown to decrease oxygen dependency and pulmonary hypertension in neonates with meconium aspiration syndrome and animal studies, respectively. We hypothesize that hydrocortisone will improve oxygenation in term and near-term infants with pulmonary hypertension. We performed a retrospective chart review of all infant with PPHN who received intravenous hydrocortisone therapy as a rescue for severe PPHN. Clinical response was objectively measured using, oxygenation index (OI), PaO<sub>2</sub>/FiO<sub>2</sub> ratio, and inotrope score before, during, and after the hydrocortisone course. We found that hydrocortisone administration resulted in significant improvement of systolic blood pressure, OI, and PaO<sub>2</sub>/FiO<sub>2.</sub> In conclusion, hydrocortisone increased systolic blood pressure and improved oxygenation in term and near-term infants with persistent pulmonary hypertension. Prospective randomized trials are required to evaluate these findings further.</p>","PeriodicalId":45027,"journal":{"name":"Clinical Medicine Insights-Pediatrics","volume":"13 ","pages":"1179556519888918"},"PeriodicalIF":1.5,"publicationDate":"2019-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1179556519888918","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49683410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
期刊
Clinical Medicine Insights-Pediatrics
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1