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Characterizing patients and family decision-maker’s expectations of participation in decision-making on thromboprophylaxis: A latent profile analysis 表征患者和家庭决策者对参与血栓预防决策的期望:一项潜在剖面分析
IF 1.2 Q3 NURSING Pub Date : 2025-12-01 DOI: 10.1016/j.jvn.2025.07.006
Fangchenglin Xu , Yongqin Yu , Yajie Deng , Yuling Ma , Yingxue Mei

Background

Shared decision-making (SDM) is a healthcare delivery model that advocates for patient-centered care in clinical practice. Examining patients and family decision-makers’ preferences on thromboprophylaxis is critical to achieving this goal.

Objective

This study aims to outline the expectations of family decision-makers regarding participation in decision-making on thromboprophylaxis.

Methods

This descriptive study examined a cross-section of a sample in the Ningxia Hui Autonomous Region People’s Hospital, a tertiary hospital in Yinchuan, China, from December 2023 to March 2024. All individuals aged ≥18 years who had undergone orthopedic surgery (total hip arthroplasty, total knee arthroplasty, or hip fracture surgery) and were at high risk for venous thromboembolism (VTE) were included in the study. They were invited to complete the four questionnaires, including the Socio-demographic List, the Control Preferences Scale (CPS, to assess patients’ role in medical decision-making), the Expectation of Participation in Medical Decision-Making Scale (to evaluate patients’ expectations for participation), and the Preparation for Decision-Making Scale (PrepDM, to assess patients’ readiness).

Results

The three profiles were designated as “High Expectation - Active Decision-Making Participation Group”(67.7%), “Medium Expectation - Neutral Decision-Making Participation Group”(26.4%), and “Low Expectation - Indifferent Decision-Making Participation Group”(5.9%). Latent influencing factors include the decision-makers employment status, kinship relationship, and level of preparedness for decision-making. In terms of employment status, the probability of employees (OR = 0.236, 95%CI = 0.062 - 0.898, p = .037) or self-employed individuals (OR = 0.213, 95%CI = 0.057 - 0.796, p = .023) belonging to the high-expectation group is the highest. Meanwhile, in relationships, the probability of spouses (OR = 0.031, 95%CI = 0.002 - 0.508, p = .012) or first-degree relatives (OR = 0.071, 95%CI = 0.008 - 0.673, p = .016) belonging to the high-expectation group is the highest. In PrepDM, the higher the total score of decision-makers, the greater the probability of belonging to the low-expectation group (OR = 1.070, 95%CI = 1.006 - 1.138, p = .031).

Conclusion

This study demonstrated heterogeneity in family decision-maker's expectations of participation in decision-making on thromboprophylaxis.

Practice implications

Stakeholders may use meaningful information to focus efforts on optimizing decisions and to develop customized bundles guided by category profiles.
共享决策(SDM)是一种在临床实践中倡导以患者为中心的医疗服务模式。检查患者和家庭决策者对血栓预防的偏好对实现这一目标至关重要。目的本研究旨在概述家庭决策者对参与血栓预防决策的期望。方法:本描述性研究于2023年12月至2024年3月在银川市三级医院宁夏回族自治区人民医院进行样本横断面分析。所有年龄≥18岁、接受过骨科手术(全髋关节置换术、全膝关节置换术或髋部骨折手术)并有静脉血栓栓塞(VTE)高风险的患者均纳入研究。他们被邀请完成四份问卷,包括社会人口学清单、控制偏好量表(CPS,评估患者在医疗决策中的角色)、参与医疗决策的期望量表(评估患者参与的期望)和决策准备量表(PrepDM,评估患者的准备程度)。结果“高期望-积极决策参与组”占67.7%,“中等期望-中立决策参与组”占26.4%,“低期望-冷漠决策参与组”占5.9%。潜在的影响因素包括决策者的就业状况、亲属关系和决策准备水平。在就业状态方面,雇员(OR = 0.236, 95%CI = 0.062 - 0.898, p = 0.037)和个体经营者(OR = 0.213, 95%CI = 0.057 - 0.796, p = 0.023)属于高期望群体的概率最高。同时,在人际关系中,配偶(OR = 0.031, 95%CI = 0.002 - 0.508, p = 0.012)或一级亲属(OR = 0.071, 95%CI = 0.008 - 0.673, p = 0.016)属于高期望群体的概率最高。在PrepDM中,决策者总得分越高,属于低期望组的概率越大(OR = 1.070, 95%CI = 1.006 ~ 1.138, p = 0.031)。结论:本研究显示家庭决策者参与血栓预防决策的期望存在异质性。实践含义涉众可以使用有意义的信息来集中精力优化决策,并开发由类别概要文件指导的定制包。
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引用次数: 0
A Prospective comparative study on analyzing the potency of mono antiplatelet therapy versus dual antiplatelet therapy in optimizing the recurrence of secondary vascular events 单抗血小板治疗与双抗血小板治疗在优化继发性血管事件复发中的效力的前瞻性比较研究
IF 1.2 Q3 NURSING Pub Date : 2025-12-01 DOI: 10.1016/j.jvn.2025.07.008
Chinmai Anugula PharmD , Suhana Begum Shaik PharmD , Rajavardhana Thamineni PharmD, Ph.D , Sasidhar Reddy Gangarapu PharmD , Shireesha Palle PharmD

Purpose

According to Global Burden of Diseases [GBD], India bares the highest burden of stroke. About 25 % of people who recover from their first stroke will have recurrence within five years. The use of antiplatelet therapy has been proven to be the best strategy available and several large studies support its use. However, the type of antiplatelet therapy used in the treatment and prevention of vascular diseases remains controversial. The present study aimed to assess the efficacy of mono and dual antiplatelet therapies in the secondary prevention of both cerebrovascular and cardiovascular events. Additionally, the study sought to provide insights into adverse drug reactions (ADRs), complications associated with antiplatelet medications, and the importance of medication adherence to enhance the quality of life in patients with these vascular events.

Methods

A prospective comparative study was conducted at Government General Hospital, Ananthapuramu, Andhra Pradesh, India. A total of 144 patients were recruited into the study.

Findings

In our study, 40 out of 105 DAPT patients were found to have recurrence of both cerebrovascular and cardiovascular events while 16 out of the 39 MAPT patients were found to have a similar recurrence. There was no statistically significant difference (p > 0.005) between DAPT and MAPT in secondary prevention of vascular events. Patient education and counseling helped in improving patient medication adherence from 17.3 % at baseline visit to 56.2 % during their second visit, which was measured by using medication adherence rating scale (MARS-10).

Implications

The findings of this study indicate that there was no statistically significant difference between DAPT and MAPT in secondary prevention of vascular events and both were considered to be equally effective in controlling incidence of recurrence of vascular events. Further research is needed to assess the long-term efficacy and safety of MAPT versus DAPT in various subgroups of patients with different vascular event profiles.
目的根据全球疾病负担(GBD),印度是中风负担最重的国家。第一次中风后康复的人中约有25%会在五年内复发。使用抗血小板治疗已被证明是最好的策略,一些大型研究支持其使用。然而,用于治疗和预防血管疾病的抗血小板疗法的类型仍然存在争议。本研究旨在评估单抗和双抗血小板治疗在脑血管和心血管事件二级预防中的疗效。此外,该研究旨在提供药物不良反应(adr),与抗血小板药物相关的并发症的见解,以及药物依从性对提高这些血管事件患者生活质量的重要性。方法在印度安得拉邦阿南塔普拉姆市政府总医院进行前瞻性比较研究。这项研究共招募了144名患者。在我们的研究中,105例DAPT患者中有40例发现有脑血管和心血管事件复发,而39例MAPT患者中有16例发现有类似的复发。DAPT与MAPT在血管事件二级预防方面差异无统计学意义(p > 0.005)。患者教育和咨询有助于提高患者的药物依从性,从基线就诊时的17.3%提高到第二次就诊时的56.2%,使用药物依从性评定量表(MARS-10)进行测量。本研究结果表明,DAPT和MAPT在血管事件二级预防方面无统计学差异,两者在控制血管事件复发率方面同样有效。需要进一步的研究来评估MAPT与DAPT在不同血管事件患者亚组中的长期疗效和安全性。
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引用次数: 0
Comparison of peripheral tissue perfusion and calf pump function in women with mild/moderate and severe chronic venous disease symptom intensity 轻/中度和重度慢性静脉疾病症状强度妇女外周血组织灌注和小腿泵功能的比较
IF 1.2 Q3 NURSING Pub Date : 2025-12-01 DOI: 10.1016/j.jvn.2025.08.004
Tiago da Silva Nogueira Pt , Maria Luiza Vieira Carvalho PhD , Rafaela Pedrosa PhD , Danielle Aparecida Gomes Pereira PhD

Objective

To compare calf muscle function and peripheral tissue perfusion in women with chronic venous disease (CVD) with mild/moderate and severe symptoms.

Methods

A cross-sectional study included women with CVD classified in stages C1, C2, and C3. The Visual Analog Scale (VAS) assessed symptomatology and divided participants into two groups. Group I reported mild/moderate symptoms (VAS of 1-6), and group II severe symptoms (VAS of 7-10). Near-infrared spectroscopy (NIRS) was used to assess peripheral tissue perfusion through in venous occlusion and movement plethysmography protocols. Total venous volume, venous filling index, calf ejection fraction, retention fraction (RF_HHB) and residual volume fraction (RVF_HHB) were measured. The assessment of calf muscle function was performed using the Heel Rise Test (HRT), considering the test time (HRT_T) and the number of repetitions (HRT_N). Fisher's exact test was used to analyze the categorical data and the Mann-Whitney U test was used to compare the variables.

Results

Fifty-five participants were included in this study. Thirty (55%) were in Group I while twenty-five (45%) were in Group II. Group I presented values of RVF_HHb of -25.42 and RF_HHb of -56.83, while group II of 56.28 and 21.50 in HHb (µmolL-1) (p=0.048 and p=0.035, respectively). Body mass index was significantly higher in group II (p=0.003). No significant difference in calf muscle function was observed between groups by HRT_T and HRT_RR.

Conclusion

Women with severe symptoms of CVD had less venous emptying and higher levels of reflux. The intensity of symptoms may be associated with high BMI levels.
目的比较轻/中、重度慢性静脉疾病(CVD)女性患者小腿肌肉功能和外周组织灌注。方法一项横断面研究纳入了分为C1、C2和C3期的CVD女性患者。视觉模拟量表(VAS)评估症状并将参与者分为两组。I组报告轻度/中度症状(VAS 1-6), II组报告重度症状(VAS 7-10)。近红外光谱(NIRS)通过静脉闭塞和运动体积描记术评估外周组织灌注。测量静脉总容积、静脉充盈指数、小腿射血分数、保留分数(rf_hbb)和残余体积分数(rvf_hbb)。考虑测试时间(HRT_T)和重复次数(HRT_N),采用脚跟上升测试(HRT)评估小腿肌肉功能。分类数据分析采用Fisher精确检验,变量比较采用Mann-Whitney U检验。结果共纳入55名受试者。第一组30例(55%),第二组25例(45%)。I组rvf_hbb为-25.42,rf_hbb为-56.83,II组hbb为56.28,21.50(µmol -1) (p=0.048, p=0.035)。II组体重指数显著高于对照组(p=0.003)。HRT_T和HRT_RR组间小腿肌肉功能无显著差异。结论CVD症状严重的女性静脉排空较少,反流水平较高。症状的强度可能与高BMI水平有关。
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引用次数: 0
Retrospective descriptive study of individuals with chronic limb-threatening ischemia (CLTI) admitted to the academic vascular surgery unit for a major lower limb amputation 慢性肢体威胁性缺血(CLTI)患者在学术血管外科接受下肢截肢的回顾性描述性研究
IF 1.2 Q3 NURSING Pub Date : 2025-12-01 DOI: 10.1016/j.jvn.2025.08.005
Catherine R. Ratliff PhD, GNP-BC, CWOCN, CFCN, WOCNF, FAAN , Virginia Rovnyak PhD

Purpose

To describe individual characteristics of those admitted in 2023 to the academic vascular surgery unit with chronic limb-threatening ischemia (CLTI) who underwent a major lower limb amputation.

Methods

A descriptive, cross-sectional retrospective chart review was conducted of major limb amputations (BKA, AKA) performed in 2023 by vascular surgery at a major academic medical center in the Southeastern United States. Variables extracted included age, sex, and comorbid conditions. Descriptive statistics (frequencies, percentages, and means) were used to describe the sample.

Results

There were 48 patients. Thirty-three were males. The mean age was 65. Thirty-seven individuals had a prior history of smoking. Other comorbidities included Coronary Artery Disease (CAD) (n = 31), Diabetes Mellitus (n = 31), Hyperlipidemia (n = 36), and Hypertension (n = 39). Those with CAD tended to have longer hospitalizations than those without CAD. The length of stay for those without CAD ranged from 4 to 19 days (median=12), while those with CAD the length of stay ranged from 3 to 65 days (median=15). Twenty-one of the 48 had a prior amputation (TMA, BKA, AKA). Forty-two patients were discharged from the hospital. The discharge destinations varied significantly with one of the patient characteristics: female sex (p = 0.005) None of the women were discharged home, while 27.6 % of the men went home. Thirty-two patients were referred to the prosthetics and orthotics department with 29 patients being fitted for a prosthetic limb. Twenty-three of the 29 (79.3 %) who underwent a BKA were fitted for a prosthesis, while 6 of the 19 (31.6 %) who underwent an AKA were fitted for a prosthesis.

Conclusion

Forty-eight patients had major lower extremity amputations on the vascular surgery unit. When the characteristics were compared between BKAs and AKAs only age was close to significance (p = 0.081), with AKAs occurring in older individuals on average, compared with BKAs. There was also evidence (p = 0.053) that the severity of the amputation was related to discharge destination, with those with an AKA discharged more often to a skilled nursing facility and less often to rehabilitation than those with a BKA. Many factors affect the ability to walk with a prosthesis such as the severity of amputation, co-morbid conditions and living situation. Multidisciplinary teams are critical to ensure improved outcomes especially for the older amputee undergoing major limb amputation.
目的描述2023年血管外科收治的慢性肢体威胁性缺血(CLTI)患者的个体特征,这些患者接受了下肢截肢。方法对美国东南部某大型学术医疗中心血管外科于2023年实施的肢体截肢(BKA, AKA)患者进行描述性、横断面回顾性分析。提取的变量包括年龄、性别和合并症。使用描述性统计(频率、百分比和平均值)来描述样本。结果共48例患者。33名男性。平均年龄为65岁。其中37人有吸烟史。其他合并症包括冠状动脉疾病(CAD) (n = 31)、糖尿病(n = 31)、高脂血症(n = 36)和高血压(n = 39)。冠心病患者比非冠心病患者住院时间更长。非CAD患者的住院时间为4至19天(中位数为12),而CAD患者的住院时间为3至65天(中位数为15)。48例患者中有21例既往截肢(TMA、BKA、AKA)。42名病人出院了。出院目的地因患者性别而有显著差异(p = 0.005)。没有女性出院回家,而27.6%的男性出院回家。32例患者被转介到修复和矫形科,其中29例患者安装了假肢。29例接受BKA的患者中有23例(79.3%)安装了假体,19例接受AKA的患者中有6例(31.6%)安装了假体。结论血管外科收治下肢大截肢48例。当比较bka和AKAs之间的特征时,只有年龄接近显著性(p = 0.081),与bka相比,AKAs平均发生在年龄较大的个体中。还有证据(p = 0.053)表明,截肢的严重程度与出院目的地有关,与BKA患者相比,AKA患者更多地出院到专业护理机构,而较少接受康复治疗。许多因素影响假肢行走的能力,如截肢的严重程度、合并症和生活环境。多学科团队是确保改善结果的关键,特别是对于接受主要肢体截肢的老年截肢者。
{"title":"Retrospective descriptive study of individuals with chronic limb-threatening ischemia (CLTI) admitted to the academic vascular surgery unit for a major lower limb amputation","authors":"Catherine R. Ratliff PhD, GNP-BC, CWOCN, CFCN, WOCNF, FAAN ,&nbsp;Virginia Rovnyak PhD","doi":"10.1016/j.jvn.2025.08.005","DOIUrl":"10.1016/j.jvn.2025.08.005","url":null,"abstract":"<div><h3>Purpose</h3><div>To describe individual characteristics of those admitted in 2023 to the academic vascular surgery unit with chronic limb-threatening ischemia (CLTI) who underwent a major lower limb amputation.</div></div><div><h3>Methods</h3><div>A descriptive, cross-sectional retrospective chart review was conducted of major limb amputations (BKA, AKA) performed in 2023 by vascular surgery at a major academic medical center in the Southeastern United States. Variables extracted included age, sex, and comorbid conditions. Descriptive statistics (frequencies, percentages, and means) were used to describe the sample.</div></div><div><h3>Results</h3><div>There were 48 patients. Thirty-three were males. The mean age was 65. Thirty-seven individuals had a prior history of smoking. Other comorbidities included Coronary Artery Disease (CAD) (<em>n</em> = 31), Diabetes Mellitus (<em>n</em> = 31), Hyperlipidemia (<em>n</em> = 36), and Hypertension (<em>n</em> = 39). Those with CAD tended to have longer hospitalizations than those without CAD. The length of stay for those without CAD ranged from 4 to 19 days (median=12), while those with CAD the length of stay ranged from 3 to 65 days (median=15). Twenty-one of the 48 had a prior amputation (TMA, BKA, AKA). Forty-two patients were discharged from the hospital. The discharge destinations varied significantly with one of the patient characteristics: female sex (<em>p</em> = 0.005) None of the women were discharged home, while 27.6 % of the men went home. Thirty-two patients were referred to the prosthetics and orthotics department with 29 patients being fitted for a prosthetic limb. Twenty-three of the 29 (79.3 %) who underwent a BKA were fitted for a prosthesis, while 6 of the 19 (31.6 %) who underwent an AKA were fitted for a prosthesis.</div></div><div><h3>Conclusion</h3><div>Forty-eight patients had major lower extremity amputations on the vascular surgery unit. When the characteristics were compared between BKAs and AKAs only age was close to significance (<em>p</em> = 0.081), with AKAs occurring in older individuals on average, compared with BKAs. There was also evidence (<em>p</em> = 0.053) that the severity of the amputation was related to discharge destination, with those with an AKA discharged more often to a skilled nursing facility and less often to rehabilitation than those with a BKA. Many factors affect the ability to walk with a prosthesis such as the severity of amputation, co-morbid conditions and living situation. Multidisciplinary teams are critical to ensure improved outcomes especially for the older amputee undergoing major limb amputation.</div></div>","PeriodicalId":45419,"journal":{"name":"Journal of Vascular Nursing","volume":"43 4","pages":"Pages 210-215"},"PeriodicalIF":1.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145712443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Venous leg ulcer services in the United Kingdom: A freedom of information request and national survey of clinicians 静脉腿溃疡服务在英国:信息自由要求和临床医生的全国调查
IF 1.2 Q3 NURSING Pub Date : 2025-12-01 DOI: 10.1016/j.jvn.2025.08.008
Mrs Layla Bolton Saghdaoui BSc , Mary Wells BSc, MSc, PhD (Professor) , Mrs Sarah Onida BSc, PhD, FRCS(Vasc) , Alun Huw Davies MA, DM, DSc, FRCS, FHEA, FEBVS, FACPh (Professor)

Background

Venous leg ulceration (VLU) guidance recommends early assessment, compression, and treatment of venous hypertension. However, it is widely perceived that many patients do not receive timely clinical management, and across the country, there are variations in services commissioned to deliver care.

Methods

A survey of clinicians and Freedom of Information Request (FOIR) explored services available to treat patients with VLU. Using Burns and Kho's guidance, a questionnaire was developed and distributed via professional networks and social media. Additionally, a simplified version of the survey was submitted to 42 Integrated Care Boards (ICBs) across England as a FOIR. Descriptive statistics and subgroup analyses were used to interpret results, and common themes categorised free-text responses.

Results

Of 39 FOIR responses, 89 % report that they have a dedicated service for lower limb wounds. Services are largely nurse-led (68 %); however, 29 % are co-led by vascular surgeons and nurses. Compression therapy is routinely provided by 94 % of services, and 79 % provide care for house-bound patients. Of those specifying ulcer duration as part of the eligibility criteria to access services, 45 % required the wound to be present for four weeks or more.
95 % of respondents reported having a dedicated vascular service, and 92 % were described as a specialist service offering surgical intervention. Most (86 %) reported having a dedicated service for venous disease, of which 39 % were multi-disciplinary led as opposed to being led by vascular surgeons alone.
In contrast to the FOIR results, of 211 clinician survey responses, only 54 % reported having access to a lower limb wound service and 57 % do not routinely refer to a leg ulcer service. While the number of VLU patients treated each month varies, 54 % of primary care services report seeing over 41 patients per month. Lower limb services are predominantly nurse-led (87 %), and compression therapy is routinely provided by 95 % of services.
Considering vascular referrals, while 68 % reported having a vascular service, only 53 % routinely referred patients with VLU. The most common indication for a referral was to rule out arterial disease. Of those not routinely referring patients, 46 % reported they were unable to make direct referrals.

Conclusion

Findings indicate that services treating VLU are available throughout England, and lower limb clinics are primarily nurse-led. However, the eligibility criteria and high demand for such services mean they are not always accessible to patients in a timely manner. Further work is needed to establish strategies to improve access to VLU services.
背景静脉下肢溃疡(VLU)指南建议早期评估、压迫和治疗静脉高压。然而,人们普遍认为,许多患者没有得到及时的临床管理,在全国范围内,委托提供护理的服务各不相同。方法通过对临床医生和信息自由要求(FOIR)的调查,探索治疗VLU患者的可用服务。在Burns和Kho的指导下,我们制作了一份调查问卷,并通过专业网络和社交媒体分发。此外,调查的简化版本作为FOIR提交给了英格兰的42个综合护理委员会(icb)。使用描述性统计和亚组分析来解释结果,并对自由文本回答进行共同主题分类。结果在39个FOIR回复中,89%报告他们有专门的下肢创伤服务。服务主要由护士主导(68%);然而,29%是由血管外科医生和护士共同领导的。94%的医疗机构常规提供压迫治疗,79%的医疗机构为足不出户的患者提供护理。在那些将溃疡持续时间作为获得服务资格标准的一部分的人中,45%要求伤口存在四周或更长时间。95%的受访者报告有专门的血管服务,92%的人被描述为提供手术干预的专家服务。大多数(86%)报告有专门的静脉疾病服务,其中39%是多学科领导,而不是由血管外科医生单独领导。与FOIR的结果相反,在211名临床医生的调查回应中,只有54%的人报告有下肢伤口服务,57%的人没有常规提及腿部溃疡服务。虽然每个月接受治疗的VLU患者人数各不相同,但54%的初级保健服务机构报告每月收治的患者超过41名。下肢服务主要由护士主导(87%),95%的服务常规提供压迫治疗。考虑到血管转诊,虽然68%的人报告有血管服务,但只有53%的人常规转诊VLU患者。最常见的转诊指征是排除动脉疾病。在那些没有常规转诊的病人中,46%的人报告说他们无法直接转诊。结论研究结果表明,全英国都有治疗VLU的服务,下肢诊所主要由护士领导。然而,资格标准和对此类服务的高需求意味着患者并不总是能够及时获得这些服务。需要进一步开展工作来制定战略,以改善获得志愿服务的机会。
{"title":"Venous leg ulcer services in the United Kingdom: A freedom of information request and national survey of clinicians","authors":"Mrs Layla Bolton Saghdaoui BSc ,&nbsp;Mary Wells BSc, MSc, PhD (Professor) ,&nbsp;Mrs Sarah Onida BSc, PhD, FRCS(Vasc) ,&nbsp;Alun Huw Davies MA, DM, DSc, FRCS, FHEA, FEBVS, FACPh (Professor)","doi":"10.1016/j.jvn.2025.08.008","DOIUrl":"10.1016/j.jvn.2025.08.008","url":null,"abstract":"<div><h3>Background</h3><div>Venous leg ulceration (VLU) guidance recommends early assessment, compression, and treatment of venous hypertension. However, it is widely perceived that many patients do not receive timely clinical management, and across the country, there are variations in services commissioned to deliver care.</div></div><div><h3>Methods</h3><div>A survey of clinicians and Freedom of Information Request (FOIR) explored services available to treat patients with VLU. Using Burns and Kho's guidance, a questionnaire was developed and distributed via professional networks and social media. Additionally, a simplified version of the survey was submitted to 42 Integrated Care Boards (ICBs) across England as a FOIR. Descriptive statistics and subgroup analyses were used to interpret results, and common themes categorised free-text responses.</div></div><div><h3>Results</h3><div>Of 39 FOIR responses, 89 % report that they have a dedicated service for lower limb wounds. Services are largely nurse-led (68 %); however, 29 % are co-led by vascular surgeons and nurses. Compression therapy is routinely provided by 94 % of services, and 79 % provide care for house-bound patients. Of those specifying ulcer duration as part of the eligibility criteria to access services, 45 % required the wound to be present for four weeks or more.</div><div>95 % of respondents reported having a dedicated vascular service, and 92 % were described as a specialist service offering surgical intervention. Most (86 %) reported having a dedicated service for venous disease, of which 39 % were multi-disciplinary led as opposed to being led by vascular surgeons alone.</div><div>In contrast to the FOIR results, of 211 clinician survey responses, only 54 % reported having access to a lower limb wound service and 57 % do not routinely refer to a leg ulcer service. While the number of VLU patients treated each month varies, 54 % of primary care services report seeing over 41 patients per month. Lower limb services are predominantly nurse-led (87 %), and compression therapy is routinely provided by 95 % of services.</div><div>Considering vascular referrals, while 68 % reported having a vascular service, only 53 % routinely referred patients with VLU. The most common indication for a referral was to rule out arterial disease. Of those not routinely referring patients, 46 % reported they were unable to make direct referrals.</div></div><div><h3>Conclusion</h3><div>Findings indicate that services treating VLU are available throughout England, and lower limb clinics are primarily nurse-led. However, the eligibility criteria and high demand for such services mean they are not always accessible to patients in a timely manner. Further work is needed to establish strategies to improve access to VLU services.</div></div>","PeriodicalId":45419,"journal":{"name":"Journal of Vascular Nursing","volume":"43 4","pages":"Pages 223-231"},"PeriodicalIF":1.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145712445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thrombosis incidence in dialysis patients: A systematic review and meta-analysis 透析患者血栓发生率:系统回顾和荟萃分析
IF 1.2 Q3 NURSING Pub Date : 2025-12-01 DOI: 10.1016/j.jvn.2025.09.001
Parisa Shiri , Shahab Rezaeian , Alireza Abdi , Alireza Khatony

Aim

To determine the incidence of thrombosis in dialysis patients and to investigate potential associated factors.

Background

Thrombosis is a common complication and a major contributor to vascular access dysfunction in dialysis patients. However, reported thrombosis incidences vary considerably across studies, and a comprehensive overview is lacking.

Methods

This systematic review and meta-analysis was conducted following PRISMA guidelines. A comprehensive search was performed in Web of Science, PubMed, Scopus, ProQuest, Ovid, Science Direct, Clinical Key, EMBASE, CINAHL, SID, and MagIran databases up to December 2023. Keywords used included "Thrombosis," "end-stage renal disease," "end-stage kidney disease," "hemodialysis," "dialysis," and their Persian equivalents. After duplicate removal and title/abstract screening, eligible articles underwent full-text review for inclusion. Data on thrombosis incidence, type, location, and study population characteristics were extracted. Heterogeneity was assessed using Cochran's Q test and I2 statistics. Methodological quality was evaluated using the STROBE checklist. Meta-analysis was performed using CMA version 2 and STATA version 14 software.

Results

Out of 12,604 identified articles, 58 studies (including 87,150 patients) met the inclusion criteria. The pooled incidence of thrombosis in dialysis patients was 14.7 % (95 % CI: 11.9–17.6). Late thrombosis incidence (7.2 %, 95 % CI: 0.4–20.3) was significantly higher than early thrombosis (2.8 %, 95 % CI: 0.6–7.9). Additionally, thrombosis incidence was significantly higher in patients older than 50 years (15.7 %, 95 % CI: 12.4–19.3) and those using arteriovenous grafts (28.7 %, 95 % CI: 22.9–34.8).

Conclusion

This meta-analysis demonstrates a high incidence of thrombosis among dialysis patients, particularly in older adults and those with arteriovenous grafts. Given the potential for serious complications, implementing preventative measures such as functional exercises, self-care education, and anticoagulation therapy in these high-risk patient populations is crucial.
目的了解透析患者血栓形成的发生率,探讨可能的相关因素。血栓形成是透析患者常见的并发症,也是导致血管通路功能障碍的主要原因。然而,各研究报告的血栓发生率差异很大,缺乏全面的概述。方法遵循PRISMA指南进行系统评价和荟萃分析。全面检索Web of Science、PubMed、Scopus、ProQuest、Ovid、Science Direct、Clinical Key、EMBASE、CINAHL、SID和MagIran数据库,检索截止日期为2023年12月。使用的关键词包括“血栓形成”、“终末期肾病”、“终末期肾病”、“血液透析”、“透析”以及它们在波斯语中的对应词。在删除重复和标题/摘要筛选后,对符合条件的文章进行全文审查以纳入。提取血栓发生率、类型、位置和研究人群特征的数据。采用Cochran’s Q检验和I2统计量评估异质性。采用STROBE检查表评估方法学质量。采用CMA version 2和STATA version 14软件进行meta分析。结果在12604篇纳入的文献中,58篇研究(包括87150例患者)符合纳入标准。透析患者血栓形成的总发生率为14.7% (95% CI: 11.9-17.6)。晚期血栓发生率(7.2%,95% CI: 0.4 ~ 20.3)明显高于早期血栓发生率(2.8%,95% CI: 0.6 ~ 7.9)。此外,50岁以上患者血栓发生率显著高于动静脉移植物患者(15.7%,95% CI: 12.4-19.3)和动静脉移植物患者(28.7%,95% CI: 22.9-34.8)。结论:该荟萃分析表明,透析患者血栓发生率高,尤其是老年人和动静脉移植患者。考虑到潜在的严重并发症,在这些高危患者群体中实施功能锻炼、自我保健教育和抗凝治疗等预防措施至关重要。
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引用次数: 0
Information for authors 作者信息
IF 1.2 Q3 NURSING Pub Date : 2025-08-19 DOI: 10.1016/S1062-0303(25)00082-2
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引用次数: 0
Information for readers 读者资讯
IF 1.2 Q3 NURSING Pub Date : 2025-08-19 DOI: 10.1016/S1062-0303(25)00083-4
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引用次数: 0
Implementation and evaluation of a supervised exercise programme for people with claudication in York, England 英国约克郡跛行患者监督锻炼计划的实施与评价
IF 1.2 Q3 NURSING Pub Date : 2025-07-30 DOI: 10.1016/j.jvn.2025.07.002
Garry A. Tew , Lisa Sharpe , Asim Abbas , Martin Bond , Alastair Jordan , Hannah Ross , Nick Hex , Rachael MacDonald , Andrew Thompson

Background

Supervised exercise therapy (SET) has been shown to improve claudication symptoms in patients with peripheral artery disease (PAD), and it is recommended as a first-line treatment in national and international guidelines. Despite this, supervised exercise programmes have not been widely implemented in many countries. This quality improvement project aimed to implement and evaluate an exercise service for people with claudication in York, England.

Methods

The York Claudication Exercise Service was launched in October 2023. Eligible patients were referred from vascular clinics at York Hospital. The service provided each participant with two, 1-hour exercise sessions per week over a 12-week programme. Standardised assessments were performed before and after the programme. Routinely assessed outcomes (e.g., recruitment, attendance, satisfaction, and treadmill walking distances) were used to evaluate the service over the first 12 months. Descriptive statistics were used to explore feasibility, acceptability, fidelity, and preliminary effects. A cost-comparison analysis was also conducted before and after the exercise service was implemented.

Results

By May 2024, 65 eligible patients had been referred, with 29 patients (44.6 %) commencing the exercise sessions. The exercise programme was delivered as intended and the median number of sessions attended was 19 (out of 24). At service exit, 13 (59.1 %) out of 22 participants reported an improvement in their claudication symptoms and were discharged to primary care. The mean (95 % CI) increase in pain-free walking distance was 110 m (39 to 182). All but one participant rated the service as ‘good’ or ‘excellent’. Economic modelling estimated that the programme would result in an annual cost-saving of £223.21 per person, or £366.40 per person using estimated costs for a future delivery model.

Conclusions

The service was successfully implemented within the existing care pathway. The evaluation indicated a high level of patient satisfaction, improvement in claudication symptoms and prevention of unnecessary referrals for vascular imaging and revascularisation. Agreements have been obtained to continue the service for at least 2 more years. During this period, sustainability funding will be sought, and the service will be adapted to improve access and uptake.
背景:监督运动疗法(SET)已被证明可以改善外周动脉疾病(PAD)患者的跛行症状,并被推荐为国家和国际指南的一线治疗方法。尽管如此,许多国家还没有广泛实施有监督的锻炼方案。本质量改进项目旨在实施和评估一项针对英国约克郡跛行患者的运动服务。方法于2023年10月推出约克郡跛行训练服务。符合条件的患者从约克医院血管诊所转介。在为期12周的计划中,该服务为每位参与者提供每周两次、每次1小时的锻炼。在项目前后进行了标准化评估。常规评估结果(例如,招募、出勤、满意度和跑步机步行距离)用于评估前12个月的服务。描述性统计用于探讨可行性、可接受性、保真度和初步效果。此外,亦进行了运动服务实施前后的成本比较分析。结果截至2024年5月,65名符合条件的患者被转诊,其中29名患者(44.6%)开始锻炼。锻炼计划按预期进行,参加会议的中位数为19次(24次中)。在服务结束时,22名参与者中有13名(59.1%)报告其跛行症状有所改善,并出院接受初级保健。无痛步行距离的平均(95% CI)增加为110米(39至182)。除了一名参与者外,所有参与者都认为这项服务“好”或“优秀”。经济模型估计,该计划将导致每人每年节省223.21英镑的成本,或使用未来交付模式的估计成本每人每年节省366.40英镑。结论该服务在现有护理路径内成功实施。评估显示患者满意度高,跛行症状改善,防止不必要的血管成像和血管重建转诊。已达成协议,继续服务至少2年。在此期间,将寻求可持续性资金,并将调整服务,以改善获取和吸收。
{"title":"Implementation and evaluation of a supervised exercise programme for people with claudication in York, England","authors":"Garry A. Tew ,&nbsp;Lisa Sharpe ,&nbsp;Asim Abbas ,&nbsp;Martin Bond ,&nbsp;Alastair Jordan ,&nbsp;Hannah Ross ,&nbsp;Nick Hex ,&nbsp;Rachael MacDonald ,&nbsp;Andrew Thompson","doi":"10.1016/j.jvn.2025.07.002","DOIUrl":"10.1016/j.jvn.2025.07.002","url":null,"abstract":"<div><h3>Background</h3><div>Supervised exercise therapy (SET) has been shown to improve claudication symptoms in patients with peripheral artery disease (PAD), and it is recommended as a first-line treatment in national and international guidelines. Despite this, supervised exercise programmes have not been widely implemented in many countries. This quality improvement project aimed to implement and evaluate an exercise service for people with claudication in York, England.</div></div><div><h3>Methods</h3><div>The York Claudication Exercise Service was launched in October 2023. Eligible patients were referred from vascular clinics at York Hospital. The service provided each participant with two, 1-hour exercise sessions per week over a 12-week programme. Standardised assessments were performed before and after the programme. Routinely assessed outcomes (e.g., recruitment, attendance, satisfaction, and treadmill walking distances) were used to evaluate the service over the first 12 months. Descriptive statistics were used to explore feasibility, acceptability, fidelity, and preliminary effects. A cost-comparison analysis was also conducted before and after the exercise service was implemented.</div></div><div><h3>Results</h3><div>By May 2024, 65 eligible patients had been referred, with 29 patients (44.6 %) commencing the exercise sessions. The exercise programme was delivered as intended and the median number of sessions attended was 19 (out of 24). At service exit, 13 (59.1 %) out of 22 participants reported an improvement in their claudication symptoms and were discharged to primary care. The mean (95 % CI) increase in pain-free walking distance was 110 m (39 to 182). All but one participant rated the service as ‘good’ or ‘excellent’. Economic modelling estimated that the programme would result in an annual cost-saving of £223.21 per person, or £366.40 per person using estimated costs for a future delivery model.</div></div><div><h3>Conclusions</h3><div>The service was successfully implemented within the existing care pathway. The evaluation indicated a high level of patient satisfaction, improvement in claudication symptoms and prevention of unnecessary referrals for vascular imaging and revascularisation. Agreements have been obtained to continue the service for at least 2 more years. During this period, sustainability funding will be sought, and the service will be adapted to improve access and uptake.</div></div>","PeriodicalId":45419,"journal":{"name":"Journal of Vascular Nursing","volume":"43 3","pages":"Pages 148-156"},"PeriodicalIF":1.2,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144864771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of nursing strategies to promote therapeutic adherence to vitamin K antagonists: A systematic review 促进维生素K拮抗剂治疗依从性的护理策略的有效性:一项系统综述
IF 1.2 Q3 NURSING Pub Date : 2025-07-28 DOI: 10.1016/j.jvn.2025.07.003
Matheus Vinicius Barbosa da Silva, Natannael da Silva Pereira, Xênia Sheila Barbosa Aguiar Queiroz, Maria Mariana Barros Melo da Silveira, Simone Maria Muniz da Silva Bezerra

Background

The incorporation of anticoagulant therapies into clinical practice has played a crucial role in reducing and preventing venous thromboembolic, cerebrovascular, and cardiopulmonary events, as well as their subsequent adverse outcomes in patients with prothrombotic conditions. Furthermore, the need for regular monitoring to maintain adequate anticoagulation levels presents a challenge in the use of vitamin K antagonists (VKAs). This study aimed to evaluate the effectiveness of strategies developed by nurses to promote therapeutic adherence to VKAs.

Methods

A comprehensive systematic review was conducted using the LILACS, BDENF, MEDLINE, ScienceDirect, and CINAHL databases. Study selection and sampling in the electronic databases were assisted by the Rayyan software. The review protocol was registered in the PROSPERO database (identifier CRD42024545808), and the report followed PRISMA guidelines.

Results

Evidence indicates that nurse-led interventions increase patients knowledge about the therapy, improve adherence to treatment and INR monitoring, extend the time within the therapeutic range, and reduce the risk of adverse outcomes related to the therapy.

Conclusion

Although more robust studies, such as multicenter randomized clinical trials, are needed, current evidence suggests that nurse-led interventions are effective and safe in promoting therapeutic adherence.
背景:在临床实践中,抗凝治疗在减少和预防静脉血栓栓塞、脑血管和心肺事件及其随后的不良后果方面发挥了至关重要的作用。此外,需要定期监测以维持足够的抗凝水平,这对使用维生素K拮抗剂(vka)提出了挑战。本研究旨在评估护士制定的策略的有效性,以促进对vka的治疗依从性。方法采用LILACS、BDENF、MEDLINE、ScienceDirect和CINAHL数据库进行综合系统评价。电子数据库中的研究选择和抽样由Rayyan软件辅助。审查方案已在PROSPERO数据库中注册(标识符CRD42024545808),报告遵循PRISMA指南。结果有证据表明,护士主导的干预措施增加了患者对治疗的认识,提高了治疗依从性和INR监测,延长了治疗范围内的时间,降低了治疗相关不良后果的风险。结论:虽然还需要更多强有力的研究,如多中心随机临床试验,但目前的证据表明,护士主导的干预措施在促进治疗依从性方面是有效和安全的。
{"title":"Effectiveness of nursing strategies to promote therapeutic adherence to vitamin K antagonists: A systematic review","authors":"Matheus Vinicius Barbosa da Silva,&nbsp;Natannael da Silva Pereira,&nbsp;Xênia Sheila Barbosa Aguiar Queiroz,&nbsp;Maria Mariana Barros Melo da Silveira,&nbsp;Simone Maria Muniz da Silva Bezerra","doi":"10.1016/j.jvn.2025.07.003","DOIUrl":"10.1016/j.jvn.2025.07.003","url":null,"abstract":"<div><h3>Background</h3><div>The incorporation of anticoagulant therapies into clinical practice has played a crucial role in reducing and preventing venous thromboembolic, cerebrovascular, and cardiopulmonary events, as well as their subsequent adverse outcomes in patients with prothrombotic conditions. Furthermore, the need for regular monitoring to maintain adequate anticoagulation levels presents a challenge in the use of vitamin K antagonists (VKAs). This study aimed to evaluate the effectiveness of strategies developed by nurses to promote therapeutic adherence to VKAs.</div></div><div><h3>Methods</h3><div>A comprehensive systematic review was conducted using the LILACS, BDENF, MEDLINE, ScienceDirect, and CINAHL databases. Study selection and sampling in the electronic databases were assisted by the Rayyan software. The review protocol was registered in the PROSPERO database (identifier CRD42024545808), and the report followed PRISMA guidelines.</div></div><div><h3>Results</h3><div>Evidence indicates that nurse-led interventions increase patients knowledge about the therapy, improve adherence to treatment and INR monitoring, extend the time within the therapeutic range, and reduce the risk of adverse outcomes related to the therapy.</div></div><div><h3>Conclusion</h3><div>Although more robust studies, such as multicenter randomized clinical trials, are needed, current evidence suggests that nurse-led interventions are effective and safe in promoting therapeutic adherence.</div></div>","PeriodicalId":45419,"journal":{"name":"Journal of Vascular Nursing","volume":"43 3","pages":"Pages 157-165"},"PeriodicalIF":1.2,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144864772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Vascular Nursing
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