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Implementation of an arterial blood gas indication algorithm in cardiac surgery 在心脏手术中实施动脉血气指示算法
IF 1 Q3 NURSING Pub Date : 2024-03-01 DOI: 10.1016/j.jvn.2023.11.008
Megan B. Wanzer DNP, AGACNP-BC, ACCNS-AG, CCRN , Tracey Wilson DNP, ACNP , Suzanna Fitzpatrick DNP, ACNP-BC, FNP-BC, FAANP

Problem

Arterial blood gasses (ABGs) account for an estimated 10-20% of all costs during an ICU stay. Non-clinically indicated ABGs increased costs of care, lengths of stay, ventilator days, and line days, increasing the risk of adverse outcomes in already vulnerable critically ill patients. A cardiac surgery intensive care unit (CSICU) within a large urban mid-Atlantic academic medical center accounted for 31% of the entire institution's ABG analyses between 2018-2019, was identified as a top utilizer due to inappropriate ordering practices compared to current guidelines.

Purpose

The purpose of this quality improvement project was to implement an algorithm using evidence-based guidelines that identified appropriate standardized clinical indications for ABGs, with the intention of reducing non-clinically indicated blood gas analyses orders within the CSICU. Anticipated outcomes of this practice change included decreasing the total volume of ABGs sent, resulting in reduced costs of care, lengths of stay, and improved morbidity and mortality rates.

Methods

An evidence-based ABG indication algorithm was created focusing on acute changes in oxygenation, ventilation, acid base balance; changes in hemodynamics, post-operative baseline, and for patient ABGs to correlate with extra-corporeal membranous oxygenation values. Routine ABGs for monitoring were eliminated. Implementation occurred over fourteen-weeks in the fall of 2020 following staff and provider education. Training emphasized the use of non-invasive monitoring such as pulse-oximetry and capnography. Compliance and gross laboratory totals and indications were obtained from weekly auditing.

Results

There was an 8.8% reduction in ABGs obtained and 32% decrease in ABGs per patient day. The most common indications were extra-corporeal membranous oxygenation (ECMO)-correlated ABGs, post-operative, and changes in oxygenation and/or ventilation; 7.8% were non-indicated.

Conclusions

Implementation of an ABG indication algorithm resulted in fewer ABGs sent, mostly due to a reduction in routine monitoring, and ABGs were more likely to be clinically indicated in response to an acute concern. Implementing an ABG indication algorithm is safe, feasible, and can lead to significant cost reductions for the institution.

问题动脉血气(ABGs)估计占重症监护病房住院期间所有费用的 10-20%。非临床需要的动脉血气检查增加了护理成本、住院时间、呼吸机天数和管路天数,增加了本已脆弱的重症患者出现不良后果的风险。大西洋沿岸中部一个大型城市学术医疗中心的心脏外科重症监护病房(CSICU)在 2018-2019 年间的 ABG 分析占整个机构的 31%,由于与现行指南相比存在不恰当的下单实践,该病房被确定为使用率最高的重症监护病房。方法建立了循证 ABG 适应症算法,重点关注氧合、通气、酸碱平衡的急性变化;血液动力学的变化、术后基线以及患者 ABG 与体外膜氧合值的相关性。用于监测的常规 ABG 被取消。在对员工和医疗服务提供者进行教育后,于 2020 年秋季开始实施,为期 14 周。培训强调了无创监测的使用,如脉搏氧饱和度监测和毛细血管造影。通过每周审计获得合规性和实验室总计以及适应症。结果:获得的 ABGs 减少了 8.8%,每个患者日 ABGs 减少了 32%。最常见的适应症是与体外膜肺氧合(ECMO)相关的 ABG、术后以及氧合和/或通气的变化;7.8% 为非适应症。结论实施 ABG 适应症算法后,发送的 ABG 减少了,这主要是由于常规监测的减少,而且 ABG 更有可能是针对急性问题的临床适应症。实施 ABG 适应症算法是安全、可行的,可为医疗机构大幅降低成本。
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引用次数: 0
The need for iliac vein stenting in women of child bearing age and the compatibility of iliac vein stents in pregnancy 育龄妇女对髂静脉支架的需求以及妊娠期髂静脉支架的兼容性
IF 1 Q3 NURSING Pub Date : 2024-03-01 DOI: 10.1016/j.jvn.2024.02.007
Patricia K. Bozeman APRN , Emily Russo BS , Mary O. Whipple PhD, RN
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引用次数: 0
Effectiveness of herbal drug Terminalia Arjuna in chronic venous insufficiency - A prospective observational study 草药 Terminalia Arjuna 对慢性静脉功能不全的疗效 - 一项前瞻性观察研究
IF 1 Q3 NURSING Pub Date : 2024-03-01 DOI: 10.1016/j.jvn.2023.11.009
KM Pratap Shankar , V. Ashwathykutty

Introduction

Chronic venous insufficiency (CVI) manifests in various clinical presentations ranging from asymptomatic but cosmetic problems to severe symptoms, such as lower limb edema, skin trophic changes, and ulceration. CVI substantially affects the quality of life and work productivity of the patients. Ayurveda, an ancient traditional medicine in India, evaluates the various pathological stages of CVI with a wide range of pathological conditions such as Siragranthi (venous abnormalities), Raktavaritavāta (disorders of vāta occluded by rakta ∼ blood), ApanaVaigunya (vitiated apānavāyu), Arsha (hemorrhoids), VataRakta (rheumatism due to rakta), Kushtha (integumentary disease) and Dushta Vrana (putrefied wound) depending upon the presentations of the patient. Ayurvedic texts mention Terminalia arjuna as a potential herb for treating various conditions related to the circulatory system. The drug is an effective anti-inflammatory, anti-oxidant, and anti-hypertensive and has a definite role in improving cardiovascular hemodynamics and wound healing. These attributes suggest that the potential of Terminalia arjuna needs to be explored as a promising venoactive drug.

Methods

This prospective observational study included 25 patients (31 limbs) with CVI who were treated with Tab Terminalia arjuna (Bark extract of Terminalia arjuna in a dose of 500 mg, given twice a day) and were observed on two visits on day 30 and day 90. Follow-up was carried out for three months to evaluate post-treatment complications or adverse effects. The clinical outcome assessment was done using Venous Clinical Severity Score (VCSS), and clinical grading was performed using clinical classification (C0 – C6) of CEAP (Clinical–Etiology–Anatomy–Pathophysiology) classification.

Results

The median VCSS score (of both limbs) during the third visit was comparatively lower than the first, with a statistically significant improvement at 0.05 level. Further, there was a substantial positive improvement in the clinical classification of CEAP among the patients in pre and post treatment phase.

Conclusion

The prospective observational study shows that Tab Terminalia arjuna is safe and effective in CVI, reducing the symptoms like pain, edema, inflammation, pigmentation, induration and also expediting ulcer healing.

导言:慢性静脉功能不全(CVI)的临床表现多种多样,既有无症状但影响美观的问题,也有下肢水肿、皮肤营养性改变和溃疡等严重症状。CVI 严重影响患者的生活质量和工作效率。阿育吠陀是印度古老的传统医学,它对 CVI 的各个病理阶段进行了评估,其中包括 Siragranthi(静脉异常)、Raktavaritavāta(被 rakta ∼ 血液堵塞的 vāta 病变)等多种病理情况、ApanaVaigunya(虚弱的 apānavāyu)、Arsha(痔疮)、VataRakta(由 rakta 引起的风湿病)、Kushtha(皮肤病)和 Dushta Vrana(腐烂的伤口),这取决于病人的表现。阿育吠陀经文提到,Terminalia arjuna 是一种潜在的草药,可用于治疗与循环系统有关的各种疾病。这种药物具有有效的抗炎、抗氧化和降压作用,在改善心血管血液动力学和伤口愈合方面具有明确的作用。这项前瞻性观察研究纳入了 25 名 CVI 患者(31 条肢体),他们接受了 Tab Terminalia arjuna(Terminalia arjuna 树皮提取物,剂量为 500 毫克,每天两次)治疗,并在第 30 天和第 90 天进行了两次随访观察。随访三个月,以评估治疗后的并发症或不良反应。临床结果评估采用静脉临床严重程度评分(VCSS),临床分级采用 CEAP(临床-病因-解剖-病理生理学)分类的临床分级(C0 - C6)。结论前瞻性观察研究表明,Tab Terminalia arjuna 对 CVI 安全有效,可减轻疼痛、水肿、炎症、色素沉着、硬化等症状,还能加快溃疡愈合。
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引用次数: 0
First pill hardest to swallow: An evaluation study of cardiovascular nurse-led follow-up phone calls 第一颗药丸最难下咽心血管病护士主导的电话随访评估研究
IF 1 Q3 NURSING Pub Date : 2024-03-01 DOI: 10.1016/j.jvn.2023.11.007
Helen Gräs Højgaard MSc(Nursing), RN , Kirsten Frederiksen PhD, MEd, RN , Annette Langager Høgh PhD, MD , Marie Dahl PhD, MSc(Nursing), RN

Introduction

Screening for cardiovascular disease (CVD) followed by preventive medication is expected to reduce CVD (2,3,5). However, insufficient medication adherence may affect screening effectiveness (11-12). It remains uncertain which interventions are suitable to support citizens in their decision-making about taking CVD preventive medication.

Objective

We evaluated if and how three nurse-led telephone follow-up (TFU) calls supported citizens in making informed decisions regarding CVD preventive medication and thereby potentially strengthened their medication adherence.

Methods

Employing a theory-based evaluation design inspired by Dahler-Larsen (39-41), we developed and tested a programme theory describing if and how the TFU calls supported medical decision-making and potentially improved medication adherence. Data were collected via telephone.

Findings

We analysed 61 TFU calls collected between May 2017 and April 2019 and found that TFU calls supported participants’ reflections on preventive medication. TFU calls supported informed decision-making regarding initiating medication, allowing participants to consider personal preferences and values, including both opting for and abstaining from medication. The content of the TFU calls revolved around four crucial themes: I) understanding the purpose of taking the medicine; II) meaningfulness and joint reflection support the decision; III) relation to healthcare professionals; and IV) taking medication for the first time.

Conclusion

TFU calls effectively supported citizens' understanding and addressed their needs. Trusted healthcare professionals' recommendations were preferred for decisional support. Initiating CVD preventive medication was particularly challenging for citizens who had not previously taken such medication. We recommend scheduling TFU calls early: the first after one week, the second after one month and the third after six months.

导言:心血管疾病(CVD)筛查后服用预防性药物有望减少心血管疾病(2,3,5)。然而,服药依从性不足可能会影响筛查效果(11-12)。我们评估了由护士主导的三次电话随访(TFU)是否以及如何支持公民就心血管疾病预防用药做出知情决定,从而可能加强他们的用药依从性。方法我们采用了受 Dahler-Larsen (39-41)启发而设计的基于理论的评估方法,开发并测试了描述电话随访是否以及如何支持医疗决策并可能改善用药依从性的方案理论。我们对 2017 年 5 月至 2019 年 4 月期间收集的 61 个 TFU 电话进行了分析,发现 TFU 电话支持参与者对预防性用药进行反思。TFU电话支持关于开始用药的知情决策,允许参与者考虑个人偏好和价值观,包括选择和放弃用药。TFU 电话会议的内容围绕四个关键主题展开:I) 了解服药的目的;II) 支持决定的意义和共同思考;III) 与医疗保健专业人员的关系;IV) 首次服药。值得信赖的医疗保健专业人员的建议是决策支持的首选。对于以前从未服用过心血管疾病预防药物的公民来说,开始服用此类药物尤其具有挑战性。我们建议尽早安排 TFU 电话:一周后第一次,一个月后第二次,六个月后第三次。
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引用次数: 0
Effectiveness of early cognitive exercise intervention on improvement cognitive function of stroke patients in the acute phase 早期认知运动干预对改善中风患者急性期认知功能的效果
IF 1 Q3 NURSING Pub Date : 2024-03-01 DOI: 10.1016/j.jvn.2023.11.010
Nurcaya , Rosyidah Arafat , Elly L. Sjattar

The purpose of this study was to assess the efficacy of early cognitive training in enhancement of cognitive function in stroke patients. This research used a quasi-experimental design, 45 patients were divided into two groups, and sequential sampling was employed. The experimental group (n = 22) received two weeks of early cognitive training six times per week, whereas the control group (n = 23) received regular hospital care. The Indonesian version of the Montreal Cognitive Assessment was used to evaluate cognitive function (MoCA-Ina). On the second day of therapy, pre-test data were taken, and post-test data were gathered after the intervention. Statistical test outcomes The MoCA-Ina score changed considerably between the intervention and control groups (p = 0.000 and p = 0.003, respectively). Several tests determined that the score was p = 0.017; the score after the intervention was substantially different between the two groups. It means cognitive function improves after exercise in the acute phase.

本研究旨在评估早期认知训练对提高脑卒中患者认知功能的疗效。本研究采用准实验设计,将 45 名患者分为两组,并采用顺序抽样法。实验组(22 人)接受为期两周、每周六次的早期认知训练,而对照组(23 人)则接受常规医院护理。印尼版蒙特利尔认知评估(MoCA-Ina)用于评估认知功能。在治疗的第二天,采集了前测数据,并在干预后收集了后测数据。统计测试结果 在干预组和对照组之间,MoCA-Ina 的得分变化很大(分别为 p = 0.000 和 p = 0.003)。经过多次测试,确定得分为 p = 0.017;干预后两组的得分有很大不同。这说明急性期运动后认知功能有所改善。
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引用次数: 0
Gujarati translation, validity and reliability of Walking Impairment Questionnaire in people with intermittent claudication due to peripheral artery disease 外周动脉疾病间歇性跛行患者步行障碍问卷的古吉拉特语翻译、有效性和可靠性
IF 1 Q3 NURSING Pub Date : 2024-03-01 DOI: 10.1016/j.jvn.2023.11.003
Darshana Naiyra , Megha Nishith Gohil , Hetshri Shah , Dr Manish Raval , Lindsay Mary Bearne

Introduction

The Walking Impairment Questionnaire (WIQ) is a common and easy-to-use assessment of walking incapacity in people with claudication due to peripheral artery disease (PAD). It has four subscales: pain severity, walking distance, walking speed, and ability to climb stairs. It has not been translated into Gujarati, which limits its use in Indian subjects.

Aim

This study aims to translate and assess the validity and reliability of a Gujarati version of WIQ.

Materials and Methods

This study had three phases: 1. Forward and backward translation and Cultural adaptation of WIQ into the Gujarati language by two independent translators, 2. Face and content validation by six clinical reviewers and 10 participants with PAD and Type II diabetes, 3. Concurrent and construct validity, test-retest reliability, and internal consistency of Gujarati, the WIQ was assessed on 160 participants with PAD and Type II diabetes who had a mean Ankle Brachial Index (standard deviation) <0.40 (0.1). The concurrent and construct validity of the WIQ was analyzed by correlating the WIQ distance and speed score with 6-minute walk distance (6MWD) and speed and WIQ total score with the Medical Outcome Study Questionnaire Short Form 36 (SF-36) score using Pearson's correlation coefficient. Test-retest reliability was analyzed using an intraclass correlation coefficient (ICC) with a seven-day interval between two questionnaire applications. Internal consistency of the total WIQ score was determined using Cronbach's alpha.

Results

Following translation, the Gujarati WIQ was considered acceptable and understandable by people with PAD. There was excellent correlation between the WIQ distance score and 6-minute walk test distance (r = 0.95, P < .05)) , the WIQ speed score and 6-minute walk test speed score (r = 0.89, P < .05)) and the Gujarati WIQ total score and total score of physical functioning domain of SF- 36 (r = 0.99, P < .05). There was excellent test-retest reliability over 7 days for total WIQ score (ICC = 0.94). The Cronbach's alpha for internal consistency of 0.97 for total WIQ score were excellent. This demonstrates the sufficient homogeneity of the total questionnaire.

Conclusion

The Gujarati version of the WIQ is reliable and valid and can be used to assess self-reported walking impairment in Gujarati-speaking people with PAD and Type II Diabetes.

导言步行障碍问卷(WIQ)是对外周动脉疾病(PAD)引起的跛行患者的步行障碍进行评估的一种常见且易于使用的方法。它有四个分量表:疼痛严重程度、行走距离、行走速度和爬楼梯能力。本研究旨在翻译和评估古吉拉特语版 WIQ 的有效性和可靠性:1.2.由六名临床审稿人和 10 名患有 PAD 和 II 型糖尿病的参与者对 WIQ 进行表面和内容验证;3.对 160 名患有 PAD 和 II 型糖尿病的参与者进行古吉拉特语 WIQ 的并发和结构效度、重测信度和内部一致性评估,这些参与者的平均踝肱指数(标准差)为 0.40 (0.1)。通过使用皮尔逊相关系数将 WIQ 距离和速度得分与 6 分钟步行距离(6MWD)和速度以及 WIQ 总分与医学结果研究问卷简表 36(SF-36)得分相关联,分析了 WIQ 的并发有效性和构建有效性。使用类内相关系数(ICC)分析了两次问卷调查间隔七天的重测可靠性。结果经翻译后,古吉拉特语 WIQ 被认为可以被 PAD 患者接受和理解。WIQ 距离得分与 6 分钟步行测试距离(r = 0.95,P <.05)、WIQ 速度得分与 6 分钟步行测试速度得分(r = 0.89,P <.05)以及古吉拉特语 WIQ 总分与 SF- 36 身体功能领域总分(r = 0.99,P <.05)之间存在极好的相关性。)WIQ 总分在 7 天内的重测可靠性极佳(ICC = 0.94)。WIQ 总分的内部一致性 Cronbach's alpha 为 0.97,非常出色。结论古吉拉特语版本的 WIQ 具有可靠性和有效性,可用于评估古吉拉特语 PAD 和 II 型糖尿病患者自我报告的行走障碍情况。
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引用次数: 0
Implementation of the Caprini risk assessment model (RAM) in surgical patients to decrease postsurgical venous thromboembolism and enoxaparin prescription at hospital discharge 在手术患者中实施卡普里尼风险评估模型 (RAM),以减少手术后静脉血栓栓塞和出院时的依诺肝素处方量
IF 1 Q3 NURSING Pub Date : 2024-03-01 DOI: 10.1016/j.jvn.2023.11.004
Hope Walden DNP, AGACNP , Eleanor Stevenson PhD, RN, FAAN , Allen Cadavero PhD, RN , Ramanathan Seshadri MD

Venous thromboembolism (VTE), including deep venous thrombosis (DVT) and pulmonary embolism (PE), has been an increasingly common post-surgical complication for surgical patients. In the United States, VTE has become a leading cause of preventable hospital death with more than half occurring after discharge and are directly linked to a recent (within 30 days) hospitalization or surgery [1]. In large, hospital-associated/acquired VTE (HA-VTE) are preventable through measures such as the use of risk stratification tools and chemoprophylaxis. The project institution, a community, academic, medical center, for multiple years has consistently remained a high outlier for postoperative VTE. Also, the choice of VTE chemoprophylaxis in surgical patients at the time of discharge depended on, and varied between, the individual prescribing physician. The goal was to implement and determine the efficacy of a standardized intervention tool, the Caprini risk assessment model (RAM), for reducing postoperative VTE complications and its influence on the physician's prescription of enoxaparin at discharge. Results: Risk assessment scoring pre-operatively increased from 0% baseline to 26.3% at Plan-Do-Study-Act (PDSA) cycle 1 and demonstrated a statistically significant change (p-value = 0.006). Risk assessment scoring pre-operatively was 42.9% by PDSA cycle 2 but was not statistically significantly different from PDSA cycle 1. Risk assessment scoring post-operatively (for eligible patients) remained the same throughout all three cycles at 0%. Appropriate prescription of anticoagulation declined from baseline (12.5%) to PDSA cycle 1 (0%), and improved at PDSA cycle 2 (33.3%), however no differences were significant (p-value 0.302). The National Surgical Quality Improvement Project (NSQIP) database showed a decline in VTE occurrences at the projects institution from baseline (1.02%, 6 occurrences, 2021) to PDSA cycle 2 (0.92%, 4 occurrences, 2022) when compared to the national benchmark (1.0%) for the first time since 2018. Given the significant national problem HA-VTE pose to the public, and the rise in occurrences, this quality improvement (QI) project is clinically relevant.

静脉血栓栓塞症(VTE),包括深静脉血栓(DVT)和肺栓塞(PE),已成为外科手术患者越来越常见的术后并发症。在美国,VTE 已成为可预防的住院死亡的主要原因,其中一半以上发生在出院后,与近期(30 天内)住院或手术直接相关[1]。在很大程度上,通过使用风险分层工具和化学预防等措施,医院相关/获得性 VTE(HA-VTE)是可以预防的。该项目机构是一家社区学术医疗中心,多年来一直是术后 VTE 的高发区。此外,手术患者出院时对 VTE 化学预防的选择取决于开具处方的医生,而且不同医生的选择也不尽相同。我们的目标是实施并确定一种标准化干预工具--卡普里尼风险评估模型(RAM)--在减少术后 VTE 并发症方面的效果及其对医生在出院时开具依诺肝素处方的影响。结果:术前风险评估评分从基线的 0% 增加到计划-实施-研究-行动 (PDSA) 周期 1 的 26.3%,并显示出显著的统计学变化(p 值 = 0.006)。到 PDSA 周期 2 时,术前风险评估得分率为 42.9%,但与 PDSA 周期 1 相比无明显统计学差异。术后风险评估得分(符合条件的患者)在三个周期内均保持不变,均为 0%。适当的抗凝处方从基线(12.5%)到 PDSA 周期 1(0%)有所下降,在 PDSA 周期 2(33.3%)有所改善,但差异不显著(P 值为 0.302)。国家外科质量改进项目(NSQIP)数据库显示,与国家基准(1.0%)相比,项目机构的 VTE 发生率从基线(1.02%,6 起,2021 年)下降到 PDSA 周期 2(0.92%,4 起,2022 年),这是 2018 年以来的首次下降。鉴于 HA-VTE 对公众造成的重大全国性问题以及发生率的上升,该质量改进 (QI) 项目具有临床相关性。
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引用次数: 0
Interprofessional collaboration in the cardiovascular management of Marfan syndrome: A qualitative study based on interviews with professionals 马凡氏综合征心血管治疗中的跨专业合作:基于专业人士访谈的定性研究
IF 1 Q3 NURSING Pub Date : 2024-03-01 DOI: 10.1016/j.jvn.2023.11.005
Tomoko Shimizu RN, PHD, Yasuko Shimizu

Background and Aim

Patients with Marfan syndrome, who present with a variety of symptoms and complex psychosocial problems, require interprofessional collaboration in their care. However, it is unclear how health care providers contribute to interprofessional collaboration for these patients. The purpose of this study was to determine the characteristics of interprofessional collaboration for patients with Marfan syndrome in the cardiovascular field.

Methods

Semi-structured interviews were conducted with health care specialists (5 physicians, 2 nurses, and 3 certified genetic counselors) were analyzed qualitatively.

Results

Based on the medical collaboration for the management of cardiovascular complications in patients and their relatives, interprofessional collaboration was identified, such as collaboration and cooperation between physicians and certified genetic counselors, and nursing practice to facilitate interprofessional collaboration. In addition, issues such as difficulties in dealing with and coordinating medical care for noncardiovascular complications, lack of specialist physicians, and lack of opportunities to collaborate with nurses were identified.

Conclusions

Effective interprofessional collaboration requires the acquisition of Marfan syndrome and genetic knowledge by healthcare providers and the development of a healthcare delivery system based on departments that can provide leadership. In addition, the assignment of nurses to work across organizational boundaries and effective collaboration between genetic counselors and nurses should be considered.

背景和目的马凡氏综合征患者会出现各种症状和复杂的社会心理问题,需要在护理过程中进行跨专业合作。然而,目前还不清楚医疗服务提供者如何促进这些患者的跨专业合作。本研究的目的是确定心血管领域针对马凡氏综合征患者的专业间协作的特点。方法对医疗保健专家(5 名医生、2 名护士和 3 名注册遗传咨询师)进行了半结构式访谈,并对访谈结果进行了定性分析。结果根据患者及其亲属心血管并发症管理的医疗协作,确定了专业间协作,如医生与注册遗传咨询师之间的协作与合作,以及促进专业间协作的护理实践。此外,还发现了一些问题,如在处理和协调非心血管并发症的医疗护理方面存在困难、缺乏专科医生、缺乏与护士合作的机会等。结论有效的跨专业合作需要医疗服务提供者掌握马凡氏综合征和遗传学知识,并以能够提供领导力的部门为基础发展医疗服务系统。此外,还应考虑指派护士跨机构工作,以及遗传咨询师和护士之间的有效合作。
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引用次数: 0
The impact of class I compression stockings on the peripheral microperfusion of the lower limb: A prospective pilot study I 级压力袜对下肢外周微灌注的影响:前瞻性试点研究
IF 1 Q3 NURSING Pub Date : 2023-12-01 DOI: 10.1016/j.jvn.2023.08.003
Andreas Lutz Heinrich Gerken , Michelle Ann Hattemer , Christel Weiß , Martin Sigl , Sebastian Zach , Michael Keese , Kai Nowak , Christoph Reißfelder , Nuh N. Rahbari , Kay Schwenke

Objective

The use of medical compression stockings (MCS) in patients with peripheral arterial disease (PAD) and diabetes is the subject of an ongoing critical debate. While reducing leg edema of various origins by improving venous back flow, there is a concern about additional arterial flow obstruction when compression therapy is applied in pre-existing PAD. The aim of this study is to obtain further information on the use of class I MCS in patients with advanced PAD and to evaluate the framework conditions for a safe application.

Methods

The total collective (n = 55) of this prospective, clinical cohort study consisted of 24 patients with PAD Fontaine stage IIb and higher studied before revascularization, of whom 16 patients were examined again after revascularization, and 15 healthy participants included for reference. The microperfusion of the lower extremity of all participants was examined in a supine, elevated, and sitting position using the oxygen to see (O2C) method.

Results

The results indicate that leg positioning had the strongest influence on microcirculation (SO2 and flow: p = 0.0001), whereas MCS had no significant effect on the perfusion parameters (SO2: p = 0.9936; flow: p = 0.4967) and did not lead to a deterioration of values into critical ranges.

Conclusion

Mild medical compression therapy appears to be feasible even in patients with advanced PAD. Larger studies are warranted to observe any long-term effects, in particular for the treatment of reperfusion edema after revascularization.

目的在患有外周动脉疾病(PAD)和糖尿病的患者中使用医疗压力袜(MCS)一直是争论的焦点。在通过改善静脉回流减轻各种原因引起的腿部水肿的同时,人们也担心在原有的 PAD 患者中使用压力疗法会造成额外的动脉血流阻塞。这项前瞻性临床队列研究的总人数(n = 55)包括在血管再通术前接受研究的 24 名方丹 IIb 期及以上 PAD 患者,其中 16 名患者在血管再通术后接受了再次检查,另外还包括 15 名健康参试者作为参考。结果表明,腿部定位对微循环的影响最大(SO2 和流量:P = 0.0001),而 MCS 对灌注参数无明显影响(SO2:p = 0.9936;血流:p = 0.4967),也不会导致数值恶化至临界范围。结论:即使是晚期 PAD 患者,轻度医疗压力疗法似乎也是可行的。需要进行更大规模的研究,以观察其长期效果,尤其是在治疗血管再通后的再灌注水肿方面。
{"title":"The impact of class I compression stockings on the peripheral microperfusion of the lower limb: A prospective pilot study","authors":"Andreas Lutz Heinrich Gerken ,&nbsp;Michelle Ann Hattemer ,&nbsp;Christel Weiß ,&nbsp;Martin Sigl ,&nbsp;Sebastian Zach ,&nbsp;Michael Keese ,&nbsp;Kai Nowak ,&nbsp;Christoph Reißfelder ,&nbsp;Nuh N. Rahbari ,&nbsp;Kay Schwenke","doi":"10.1016/j.jvn.2023.08.003","DOIUrl":"10.1016/j.jvn.2023.08.003","url":null,"abstract":"<div><h3>Objective</h3><p>The use of medical compression stockings (MCS) in patients with peripheral arterial disease (PAD) and diabetes is the subject of an ongoing critical debate. While reducing leg edema of various origins by improving venous back flow, there is a concern about additional arterial flow obstruction when compression therapy is applied in pre-existing PAD. The aim of this study is to obtain further information on the use of class I MCS in patients with advanced PAD and to evaluate the framework conditions for a safe application.</p></div><div><h3>Methods</h3><p>The total collective (<em>n</em> = 55) of this prospective, clinical cohort study consisted of 24 patients with PAD Fontaine stage IIb and higher studied before revascularization, of whom 16 patients were examined again after revascularization, and 15 healthy participants included for reference. The microperfusion of the lower extremity of all participants was examined in a supine, elevated, and sitting position using the oxygen to see (O2C) method.</p></div><div><h3>Results</h3><p>The results indicate that leg positioning had the strongest influence on microcirculation (SO2 and flow: <em>p</em> = 0.0001), whereas MCS had no significant effect on the perfusion parameters (SO2: <em>p</em> = 0.9936; flow: <em>p</em> = 0.4967) and did not lead to a deterioration of values into critical ranges.</p></div><div><h3>Conclusion</h3><p>Mild medical compression therapy appears to be feasible even in patients with advanced PAD. Larger studies are warranted to observe any long-term effects, in particular for the treatment of reperfusion edema after revascularization.</p></div>","PeriodicalId":45419,"journal":{"name":"Journal of Vascular Nursing","volume":"41 4","pages":"Pages 212-218"},"PeriodicalIF":1.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135299510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Asymptomatic peripheral arterial disease in HIV patients in Ghana: A case-control study 加纳HIV患者无症状外周动脉疾病的病例对照研究
IF 1 Q3 NURSING Pub Date : 2023-12-01 DOI: 10.1016/j.jvn.2023.07.001
Kwame Yeboah , Latif Musah , Samuel Essel , Jennifer Adjepong Agyekum , Kweku Bedu-Addo

Background

Peripheral arterial disease (PAD) is common in HIV patients and can be diagnosed noninvasively using the ankle-brachial index (ABI). The burden of PAD has not been investigated in Ghanaian HIV patients. We investigated the prevalence and risk factors associated with PAD in HIV patients at a periurban hospital in Ghana.

Methods

In a case-control design, ABI was measured in 158 cART-treated HIV patients, 150 cART-naïve HIV patients and 156 non-HIV controls with no clinical symptoms of CVDs. PAD was defined as ABI ≤ 0.9. A structured questionnaire was used to collect socio-demographic and clinical data. Fasting venous blood samples were collected to measure plasma levels of glucose, lipid profile, and CD4+ lymphocytes.

Results

The prevalence of PAD was 13.9% among cART-treated HIV patients, 21.3% among cART-naïve HIV patients, and 15.4% among non-HIV controls. Patients with PAD had increased odds of having low CD4+ cell counts [OR (95% CI) = 3.68 (1.41–12.85)]. In cART-treated HIV patients, those on TDF-based [5.76 (1.1–30.01), p = 0.038] and EFV-based [9.28 (1.51–57.12), p = 0.016] regimens had increased odds of having PAD.

Conclusion

In our study population, there was no difference in the prevalence of PAD between cART-treated HIV patients compared to cART-naïve HIV patients or non-HIV controls. Having a low CD4 cell count and being on TDF- or EFV-based regimens were associated with an increased likelihood of having PAD.

背景外周动脉疾病(PAD)在艾滋病患者中很常见,可通过踝肱指数(ABI)进行无创诊断。加纳艾滋病患者的 PAD 负担尚未得到调查。我们对加纳一家城郊医院的 HIV 患者中 PAD 的患病率和相关风险因素进行了调查。方法采用病例对照设计,对 158 名接受过 cART 治疗的 HIV 患者、150 名未接受过 cART 治疗的 HIV 患者和 156 名无心血管疾病临床症状的非 HIV 对照者进行了 ABI 测量。ABI≤0.9定义为PAD。采用结构化问卷收集社会人口学和临床数据。收集空腹静脉血样本以测量血糖、血脂和 CD4+ 淋巴细胞的血浆水平。结果在接受过 cART 治疗的 HIV 患者中,PAD 患病率为 13.9%;在接受过 cART 治疗的 HIV 患者中,PAD 患病率为 21.3%;在非 HIV 对照组中,PAD 患病率为 15.4%。PAD患者CD4+细胞计数低的几率增加[OR (95% CI) = 3.68 (1.41-12.85)]。在接受 cART 治疗的 HIV 患者中,接受基于 TDF [5.76 (1.1-30.01),p = 0.038] 和基于 EFV [9.28 (1.51-57.12),p = 0.016] 方案的患者出现 PAD 的几率增加。CD4细胞计数低、使用基于TDF或EFV的治疗方案与PAD患病几率增加有关。
{"title":"Asymptomatic peripheral arterial disease in HIV patients in Ghana: A case-control study","authors":"Kwame Yeboah ,&nbsp;Latif Musah ,&nbsp;Samuel Essel ,&nbsp;Jennifer Adjepong Agyekum ,&nbsp;Kweku Bedu-Addo","doi":"10.1016/j.jvn.2023.07.001","DOIUrl":"10.1016/j.jvn.2023.07.001","url":null,"abstract":"<div><h3>Background</h3><p>Peripheral arterial disease (PAD) is common in HIV patients and can be diagnosed noninvasively using the ankle-brachial index (ABI). The burden of PAD has not been investigated in Ghanaian HIV patients. We investigated the prevalence and risk factors associated with PAD in HIV patients at a periurban hospital in Ghana.</p></div><div><h3>Methods</h3><p>In a case-control design, ABI was measured in 158 cART-treated HIV patients, 150 cART-naïve HIV patients and 156 non-HIV controls with no clinical symptoms of CVDs. PAD was defined as ABI ≤ 0.9. A structured questionnaire was used to collect socio-demographic and clinical data. Fasting venous blood samples were collected to measure plasma levels of glucose, lipid profile, and CD4+ lymphocytes.</p></div><div><h3>Results</h3><p>The prevalence of PAD was 13.9% among cART-treated HIV patients, 21.3% among cART-naïve HIV patients, and 15.4% among non-HIV controls. Patients with PAD had increased odds of having low CD4+ cell counts [OR (95% CI) = 3.68 (1.41–12.85)]. In cART-treated HIV patients, those on TDF-based [5.76 (1.1–30.01), p = 0.038] and EFV-based [9.28 (1.51–57.12), p = 0.016] regimens had increased odds of having PAD.</p></div><div><h3>Conclusion</h3><p>In our study population, there was no difference in the prevalence of PAD between cART-treated HIV patients compared to cART-naïve HIV patients or non-HIV controls. Having a low CD4 cell count and being on TDF- or EFV-based regimens were associated with an increased likelihood of having PAD.</p></div>","PeriodicalId":45419,"journal":{"name":"Journal of Vascular Nursing","volume":"41 4","pages":"Pages 203-208"},"PeriodicalIF":1.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45417955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Vascular Nursing
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