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Stuck on a diagnosis: prosthetic mitral valve thrombosis vs dyssynchrony. 被诊断困住了:假体二尖瓣血栓vs非同步化。
IF 6.3 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2020-09-01 DOI: 10.1530/ERP-20-0012
Patrick Savage, Michael Connolly

Prosthetic valve thrombosis is a rare but serious complication of mechanical valve replacement requiring prompt diagnosis and treatment. Unfortunately, it is often difficult to evaluate this based on single modality imaging alone. We demonstrate a case where the use of both 3D-TOE and valve fluoroscopy allowed for the differentiation between prosthetic valve thrombosis vs prosthetic mitral valve dyssychrony. Using transoesphageal echocardiography, it is noted that there is valve dyssynchrony; however, it is unclear if there is leaflet restriction (Video 1). Using fluoroscopy, it can be seen clearly that their overall mobility is normal (Video 2). Additionally, using 3D-TOE it can be clearly noted that there is no evidence of pannus or thrombus (Video 3). Using these two imaging modalities in concert facilitated the clear diagnosis of valve dyssynchrony vs valve thrombosis.

人工瓣膜血栓形成是机械瓣膜置换术中一种罕见但严重的并发症,需要及时诊断和治疗。不幸的是,仅基于单模成像通常很难评估这一点。我们展示了一个病例,其中使用3D-TOE和瓣膜透视允许区分人工瓣膜血栓与人工二尖瓣不同步。经食管超声心动图显示存在瓣膜不同步;然而,不清楚是否存在小叶限制(视频1)。通过透视,可以清楚地看到它们的整体活动正常(视频2)。此外,使用3D-TOE可以清楚地注意到没有血栓或血栓的证据(视频3)。将这两种成像方式结合使用有助于明确诊断瓣膜非同步化与瓣膜血栓形成。
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引用次数: 0
Left ventricular speckle tracking echocardiographic evaluation before and after TAVI. TAVI前后左心室斑点跟踪超声心动图评价。
IF 6.3 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2020-09-01 DOI: 10.1530/ERP-20-0009
Vasiliki Tsampasian, Vasileios Panoulas, Richard J Jabbour, Neil Ruparelia, Iqbal S Malik, Nearchos Hadjiloizou, Angela Frame, Sayan Sen, Nilesh Sutaria, Ghada W Mikhail, Petros Nihoyannopoulos

Aims: To assess left ventricular (LV) function before and after transcatheter aortic valve implantation (TAVI) using conventional echocardiographic parameters and global longitudinal LV strain (GLS) and compare outcomes between Edwards S3 and Evolut R valves.

Methods and results: Data were collected for consecutive patients undergoing TAVI at Hammersmith hospital between 2015 and 2018. Of the 303 patients, those with coronary artery disease and atrial fibrillation were excluded leading to a total of 85 patients, which constituted our study group. The mean follow-up was 49 ± 39 days. In total, 60% of patients were treated with Edwards S3 and 40% Evolut R. TAVI resulted in an early improvement of GLS (-13.96 to -15.25%, P = 0.01) but not ejection fraction (EF) (47.6 to 50.1%, P = 0.09). LV mass also improved, especially in patients with marked baseline LV hypertrophy (P < 0.001). There were no appreciable differences of LV function improvement and overall LV remodelling after TAVI between the two types of valves used (P = 0.14).

Conclusions: TAVI results in reverse remodelling and improvement of GLS, especially in patients with impaired baseline LV function. There were no differences in the extent of LV function improvement between Edwards S3 and Evolut R valves but there was a greater incidence of aortic regurgitation with Evolut R.

目的:利用常规超声心动图参数和左室纵向应变(GLS)评价经导管主动脉瓣植入术(TAVI)前后左室功能,并比较Edwards S3和Evolut R瓣膜的效果。方法与结果:收集2015年至2018年在Hammersmith医院连续接受TAVI的患者的数据。303例患者中,排除冠状动脉疾病和心房颤动患者,共85例患者构成我们的研究组。平均随访时间为49±39天。总的来说,60%的患者接受Edwards S3治疗,40%的患者接受Evolut r治疗。TAVI导致GLS的早期改善(-13.96 ~ -15.25%,P = 0.01),但没有射血分数(EF) (47.6 ~ 50.1%, P = 0.09)。左室质量也有所改善,特别是基线左室肥厚明显的患者(P < 0.001)。两种瓣膜在TAVI后左室功能改善和整体左室重构方面无明显差异(P = 0.14)。结论:TAVI可导致GLS的反向重构和改善,特别是在基线左室功能受损的患者中。Edwards S3和Evolut R瓣膜在左室功能改善程度上没有差异,但Evolut R瓣膜的主动脉反流发生率更高。
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引用次数: 2
Global longitudinal strain in chronic asymptomatic aortic regurgitation: systematic review. 慢性无症状主动脉反流的整体纵向应变:系统综述。
IF 6.3 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2020-09-01 DOI: 10.1530/ERP-20-0024
Diana deCampos, Rogério Teixeira, Carolina Saleiro, Ana Botelho, Lino Gonçalve

Chronic aortic regurgitation (AR) patients typically remain asymptomatic for a long time. Left ventricular mechanics, namely global longitudinal strain (GLS), has been associated with outcomes in AR patients. The authors conducted a systematic review to summarize and appraise GLS impact on mortality, the need for aortic valve replacement (AVR) and disease progression in AR patients. A literature search was performed using these key terms 'aortic regurgitation' and 'longitudinal strain' looking at all randomized and nonrandomized studies conducted on chronic aortic regurgitation. The search yielded six observational studies published from 2011 and 2018 with a total of 1571 patients with moderate to severe chronic AR. Only two studies included all-cause mortality as their endpoint. The other studies looked at the association between GLS with AVR and disease progression. The mean follow-up period was 4.2 years. We noted a great variability of clinical, methodological and/or statistical origin. Thus, meta-analytic portion of our study was limited. Despite a relevant heterogeneity, an impaired GLS was associated with adverse cardiac outcomes. Left ventricular GLS may offer incremental value in risk stratification and decision-making.

慢性主动脉反流(AR)患者通常在很长一段时间内保持无症状。左心室力学,即全局纵向应变(GLS)与AR患者的预后有关。作者进行了一项系统综述,总结和评估GLS对AR患者死亡率、主动脉瓣置换术(AVR)需求和疾病进展的影响。使用“主动脉反流”和“纵向应变”这两个关键词进行文献检索,查看所有针对慢性主动脉反流进行的随机和非随机研究。该搜索产生了2011年至2018年发表的六项观察性研究,共有1571名中度至重度慢性AR患者,其中只有两项研究将全因死亡率作为终点。其他研究着眼于GLS与AVR和疾病进展之间的关系。平均随访时间为4.2年。我们注意到临床、方法学和/或统计来源的巨大差异。因此,我们研究的元分析部分是有限的。尽管存在相关的异质性,GLS受损与心脏不良结局相关。左心室GLS可能在风险分层和决策方面提供增加价值。
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引用次数: 2
A minimum dataset for a Level 1 echocardiogram: a guideline protocol from the British Society of Echocardiography. 1级超声心动图的最小数据集:英国超声心动图学会的指导方案。
IF 6.3 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2020-06-01 DOI: 10.1530/ERP-19-0060
Rakhee Hindocha, David Garry, Nadia Short, Tom E Ingram, Richard P Steeds, Claire L Colebourn, Keith Pearce, Vishal Sharma

The British Society of Echocardiography has previously outlined a minimum dataset for a standard transthoracic echocardiogram, and this remains the basis on which an echocardiographic study should be performed. The importance of ultrasound in excluding critical conditions that may require urgent treatment is well known. Several point-of-care echo protocols have been developed for use by non-echocardiography specialists. However, these protocols are often only used in specific circumstances and are usually limited to 2D echocardiography. Furthermore, although the uptake in training for these protocols has been reasonable, there is little in the way of structured support available from accredited sonographers in the ongoing training and re-accreditation of those undertaking these point-of-care scans. In addition, it is well recognised that the provision of echocardiography on a 24/7 basis is extremely challenging, particularly outside of tertiary cardiac centres. Consequently, following discussions with NHS England, the British Society of Echocardiography has developed the Level 1 echocardiogram in order to support the rapid identification of critical cardiac pathology that may require emergency treatment. It is intended that these scans will be performed by non-specialists in echocardiography and crucially are not designed to replace a full standard transthoracic echocardiogram. Indeed, it is expected that a significant number of patients, in whom a Level 1 echocardiogram is required, will need to have a full echocardiogram performed as soon as is practically possible. This document outlines the minimum dataset for a Level 1 echocardiogram. The accreditation process for Level 1 echo is described separately.

英国超声心动图学会先前概述了标准经胸超声心动图的最低数据集,这仍然是超声心动图研究的基础。超声在排除可能需要紧急治疗的危急情况方面的重要性是众所周知的。几个点护理回声协议已开发用于非超声心动图专家。然而,这些方案通常只在特定情况下使用,通常仅限于二维超声心动图。此外,尽管对这些方案的培训是合理的,但在正在进行的培训和对进行这些护理点扫描的人员的重新认证中,获得认证的超声医师提供的结构化支持很少。此外,众所周知,全天候提供超声心动图是极具挑战性的,特别是在三级心脏中心之外。因此,在与英国国家医疗服务体系讨论后,英国超声心动图学会开发了1级超声心动图,以支持快速识别可能需要紧急治疗的关键心脏病理。这些扫描将由非超声心动图专家进行,关键的是,这些扫描不是为了取代完整的标准经胸超声心动图而设计的。事实上,预计大量需要1级超声心动图的患者将需要尽快进行全面的超声心动图检查。本文档概述了1级超声心动图的最小数据集。1级回声的认证过程单独描述。
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引用次数: 9
Normal reference intervals for cardiac dimensions and function for use in echocardiographic practice: a guideline from the British Society of Echocardiography. 超声心动图实践中心脏尺寸和功能的正常参考区间:英国超声心动图学会指南。
IF 6.3 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2020-03-20 DOI: 10.1530/ERP-19-0050
Allan Harkness, Liam Ring, Daniel X Augustine, David Oxborough, Shaun Robinson, Vishal Sharma

The authors and journal apologise for errors in the above paper, which appeared in the March 2020 issue of Echo Research and Practice (volume 7, pages G1–G18, https://doi.org/10.1530/ERP-19-0050).The errors relate to values given in Table 2 on page G6. The original text gave the Male moderate LVIDd LV dimension as 61–65 mm, the Male mild LVIDs LV dimension as 41–45 mm and the Female mild LVMi LV mass as 98–115 g/m2.This should have stated that the Male moderate LVIDd LV dimension is 62–65 mm, the Male mild LVIDs LV dimension is 42–45 mm and the Female mild LVMi LV mass is 100–115 g/m2. The corrected Table 2 is given in full below:

上述论文发表在2020年3月的《回声研究与实践》(第7卷,G1-G18页,https://doi.org/10.1530/ERP-19-0050).The)上,作者和期刊为上述论文中的错误道歉。原文给出男性中度LVIDd LV尺寸为61 ~ 65 mm,男性轻度LVIDs LV尺寸为41 ~ 45 mm,女性轻度LVMi LV质量为98 ~ 115 g/m2。这应该说明男性中度LVIDd LV尺寸为62-65 mm,男性轻度LVIDd LV尺寸为42-45 mm,女性轻度LVMi LV质量为100-115 g/m2。更正后的表2全文如下:
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引用次数: 81
Normal reference intervals for cardiac dimensions and function for use in echocardiographic practice: a guideline from the British Society of Echocardiography 超声心动图实践中使用的心脏尺寸和功能的正常参考间隔:英国超声心动图学会的指南
IF 6.3 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2020-03-01 DOI: 10.1530/ERP-19-0050e
A. Harkness, L. Ring, D. Augustine, D. Oxborough, Shaun Robinson, V. Sharma
The authors and journal apologise for errors in the above paper, which appeared in the March 2020 issue of Echo Research and Practice (volume 7, pages G1–G18, https://doi.org/10.1530/ERP-19-0050).The errors relate to values given in Table 2 on page G6. The original text gave the Male moderate LVIDd LV dimension as 61–65 mm, the Male mild LVIDs LV dimension as 41–45 mm and the Female mild LVMi LV mass as 98–115 g/m2.This should have stated that the Male moderate LVIDd LV dimension is 62–65 mm, the Male mild LVIDs LV dimension is 42–45 mm and the Female mild LVMi LV mass is 100–115 g/m2. The corrected Table 2 is given in full below:
作者和期刊为上述论文中的错误道歉,该论文发表在2020年3月的《回声研究与实践》(第7卷,G1-G18页,https://doi.org/10.1530/ERP-19-0050)错误与G6页表2中给出的值有关。原文给出男性中度LVIDd LV尺寸为61–65 mm,男性轻度LVIDs LV尺寸为41–45 mm,女性轻度LVMi LV质量为98–115 g/m2。本应说明男性中度LVID LV尺寸为62–65 mm、男性轻度LVID LV大小为42–45 mm、女性轻度LVMi LV质量为100–115 g/m2。修正后的表2全文如下:
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引用次数: 11
Echocardiographic assessment of the right heart in adults: a practical guideline from the British Society of Echocardiography 成人右心超声心动图评估:英国超声心动图学会实用指南
IF 6.3 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2020-02-27
Abbas Zaidi, Daniel S Knight, Daniel X Augustine, Allan Harkness, David Oxborough, Keith Pearce, Liam Ring, Shaun Robinson, Martin Stout, James Willis, Vishal Sharma

The structure and function of the right side of the heart is influenced by a wide range of physiological and pathological conditions. Quantification of right heart parameters is important in a variety of clinical scenarios including diagnosis, prognostication, and monitoring response to therapy. Although echocardiography remains the first-line imaging investigation for right heart assessment, published guidance is relatively sparse in comparison to that for the left ventricle. This guideline document from the British Society of Echocardiography describes the principles and practical aspects of right heart assessment by echocardiography, including quantification of chamber dimensions and function, as well as assessment of valvular function. While cut-off values for normality are included, a disease-oriented approach is advocated due to the considerable heterogeneity of structural and functional changes seen across the spectrum of diseases affecting the right heart. The complex anatomy of the right ventricle requires special considerations and echocardiographic techniques, which are set out in this document. The clinical relevance of right ventricular diastolic function is introduced, with practical guidance for its assessment. Finally, the relatively novel techniques of three-dimensional right ventricular echocardiography and right ventricular speckle tracking imaging are described. Despite these techniques holding considerable promise, issues relating to reproducibility and inter-vendor variation have limited their clinical utility to date.

心脏右侧的结构和功能受到广泛的生理和病理条件的影响。量化右心参数在各种临床情况下都很重要,包括诊断、预后和监测对治疗的反应。尽管超声心动图仍然是右心评估的一线影像学研究,但与左心室相比,已发表的指导相对较少。这份来自英国超声心动图学会的指导文件描述了通过超声心动图评估右心的原理和实践方面,包括心室尺寸和功能的量化,以及瓣膜功能的评估。虽然包括正常的临界值,但由于在影响右心的各种疾病中看到的结构和功能变化具有相当大的异质性,因此提倡以疾病为导向的方法。右心室复杂的解剖结构需要特殊的考虑和超声心动图技术,这在本文中列出。介绍了右心室舒张功能的临床意义,并对其评估提供了实用指导。最后,介绍了三维右室超声心动图和右室散斑跟踪成像技术。尽管这些技术具有相当大的前景,但迄今为止,与可重复性和供应商之间的差异有关的问题限制了它们的临床应用。
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引用次数: 0
Normal reference intervals for cardiac dimensions and function for use in echocardiographic practice: a guideline from the British Society of Echocardiography. 用于超声心动图检查的心脏尺寸和功能正常参考区间:英国超声心动图学会指南。
IF 3.2 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2020-02-24
Allan Harkness, Liam Ring, Daniel X Augustine, David Oxborough, Shaun Robinson, Vishal Sharma

This guideline presents reference limits for use in echocardiographic practice, updating previous guidance from the British Society of Echocardiography. The rationale for change is discussed, in addition to how the reference intervals were defined and the current limitations to their use. The importance of interpretation of echocardiographic parameters within the clinical context is explored, as is grading of abnormality. Each of the following echo parameters are discussed and updated in turn: left ventricular linear dimensions and LV mass; left ventricular volumes; left ventricular ejection fraction; left atrial size; right heart parameters; aortic dimensions; and tissue Doppler imaging. There are several important conceptual changes to the assessment of the heart’s structure and function within this guideline. New terminology for left ventricular function and left atrial size are introduced. The British Society of Echocardiography has advocated a new approach to the assessment of the aortic root, the right heart, and clarified the optimal methodology for assessment of LA size. The British Society of Echocardiography has emphasized a preference to use, where feasible, indexed measures over absolute values for any chamber size.

本指南对英国超声心动图学会以前的指南进行了更新,提出了超声心动图实践中使用的参考区间。除了参考区间的定义及其目前的使用限制外,还讨论了更改的理由。此外,还探讨了在临床背景下解释超声心动图参数的重要性以及异常分级。依次讨论并更新了以下各项超声参数:左心室线性尺寸和左心室质量;左心室容积;左心室射血分数;左心房大小;右心参数;主动脉尺寸;组织多普勒成像。本指南在评估心脏结构和功能方面有几处重要的概念性改变。其中引入了左心室功能和左心房大小的新术语。英国超声心动图学会提倡采用新方法评估主动脉根部和右心,并明确了评估 LA 大小的最佳方法。英国超声心动图学会强调,在可行的情况下,任何心腔的大小都应优先使用指数测量法,而非绝对值。
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引用次数: 0
Is this a satellite orbiting unchartered territory? 这是一颗绕未知区域运行的卫星吗?
IF 6.3 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2020-02-17 eCollection Date: 2020-03-01 DOI: 10.1530/ERP-19-0061
Handi Salim, Martin Been, David Hildick-Smith, Jamal Nasir Khan
A 27-year old female i.v. drug user presented to our institution with chest pain. She had a history of bicuspid aortic valve endocarditis with aortic root abscess repaired with bioprosthetic aortic valve replacement and pericardial patch reconstruction of the left ventricular outflow tract and non-coronary sinus 6 weeks previously. Echocardiographic and cardiac CT imaging confirmed three foci of breakdown of the pericardial patch repair with active bleeding into a large posterior pseudoaneurysm (92 mm diameter) compressing the left atrium and pulmonary artery. Following multidisciplinary discussion, the consensus was to attempt urgent percutaneous closure of the defect, given the prohibitive surgical risks. The procedure was performed under fluoroscopic and 3D-transoesophageal guidance. TOE demonstrated the pericardial patch breaches and active bleeding into the large pseudoaneurysm (Figs 1 and 2). Initial deployment of an Amplatzer atrial septal defect occluder resulted in significant flow reduction, but there remained two small peri-device leaks (Fig. 3). During an attempt to implant an additional smaller Amplatzer vascular plug (AVP-2) to rectify this, the initial device dislodged and embolised into the pseudoaneurysm. This was felt irretrievable and unlikely to be clinically significant given its containment. The embolised device freely floated within the pseudoaneurysm, uniquely akin to a satellite orbiting in space (Video 1). The secondary device was removed and initial breach was satisfactorily closed with a 15-mm-sized Amplatzer atrial septal defect occluder (third device). This was confirmed to be wellseated on real-time 3D imaging (Video 2), with negligible residual leak on TOE (Fig. 4). This is the first published case of percutaneous cardiac device embolization into a pseudoaneurysm cavity that we are aware of. ID: XX-XXXX;
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引用次数: 0
British Society of Echocardiography Departmental Accreditation Standards 2019 with input from the Intensive Care Society. 2019年英国超声心动图部门认证标准协会,并得到重症监护协会的投入。
IF 6.3 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2020-02-17 eCollection Date: 2020-03-01 DOI: 10.1530/ERP-19-0045
Sarah Ritzmann, Stephanie Baker, Marcus Peck, Tom E Ingram, Jane Allen, Laura Duffy, Richard P Steeds, Andrew Houghton, Andrew Elkington, Nina Bual, Robert Huggett, Keith Pearce, Stavros Apostolakis, Khalatabari Afshin

This article sets out a summary of standards for departmental accreditation set by the British Society of Echocardiography (BSE) Departmental Accreditation Committee. Full accreditation standards are available at www.bsecho.org. The BSE were the first national organisation to establish a quality standards framework for departments that support the practice of individual echocardiographers. This is an updated version which recognises that, not only should all echocardiographers be individually accredited as competent to practice, but that departments also need to be well organised and have the facilities, equipment and processes to ensure the services they deliver are of an appropriate clinical standard. In combination with individual accreditation, departmental accreditation lays down standards to help ensure safe and effective patient care. These standards supersede the 2012 BSE Departmental Accreditation Standards. Standards are set to cover all potential areas of practice, including transthoracic (level 2) echocardiography, transoesophageal echocardiography, stress echocardiography, training, and emergency (level 1) echocardiography. The emergency echocardiography standard is a new addition to departmental accreditation and has been developed with input from the Intensive Care Society.

本文概述了由英国超声心动图学会(BSE)部门认证委员会制定的部门认证标准。完整的认证标准可在www.bsecho.org上获得。BSE是第一个为支持个人超声心动图医师实践的部门建立质量标准框架的国家组织。这是一个更新的版本,它认识到,不仅所有超声心动图师都应该被单独认可为有能力的执业,而且各部门也需要组织良好,拥有设施、设备和流程,以确保他们提供的服务符合适当的临床标准。部门认证与个人认证相结合,制定了标准,以帮助确保安全有效的病人护理。这些标准取代2012年疯牛病部门认证标准。标准涵盖了所有潜在的实践领域,包括经胸(2级)超声心动图、经食管超声心动图、应激超声心动图、训练和急诊(1级)超声心动图。急诊超声心动图标准是部门认证的新成员,是根据重症监护学会的意见制定的。
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引用次数: 5
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Echo Research and Practice
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