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Coexisting Thyroglossal Duct Cyst with Papillary Thyroid Cancer: A Case Report and Literature Review. 甲状腺舌管囊肿合并甲状腺乳头状癌1例报告并文献复习。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-12-26 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6111308
Abdullah A Alarfaj, Ahmed Zekri, Ibrahim Alyaeesh, Ahmed Alomairin, Abdulrahman Al Naim

Thyroglossal duct cysts (TGDCs) are common developmental anomalies in which the thyroglossal duct is not obliterated. Coexisting papillary thyroid cancer and TGDC are uncommon and should be investigated thoroughly to rule out TGDC carcinoma. We report a rare case of coexisting papillary thyroid cancer and TGDC in a 48-year-old man, who presented with a history of recurrent mild painful midline neck swelling, and ultrasound (US) revealed a TGDC that was subsequently managed conservatively. On follow-up after 1.6 years, a thyroid US and a fine-needle aspiration (FNA) biopsy were performed, which showed malignant papillary thyroid carcinoma. Total thyroidectomy, the Sistrunk procedure, and central neck dissection were implemented. After three days, the patient was discharged on 150 mg of levothyroxine. Follow-up was unremarkable with no complications. The authors would like to stress the importance of regular TGDC and thyroid gland follow-ups for early detection and diagnosis of thyroid malignancy via clinical examination and US.

甲状舌管囊肿(TGDCs)是常见的发育异常,甲状舌管未完全消失。甲状腺乳头状癌与TGDC共存并不常见,应彻底检查以排除TGDC癌。我们报告一例罕见的乳头状甲状腺癌和TGDC共存的病例,患者为48岁男性,其表现为复发性轻度疼痛颈部中线肿胀史,超声(US)显示TGDC,随后进行保守治疗。在1.6年后的随访中,进行了甲状腺US和细针穿刺(FNA)活检,显示为恶性甲状腺乳头状癌。实施甲状腺全切除术、Sistrunk手术和中央颈部清扫术。三天后,患者给予150毫克左甲状腺素出院。随访无显著差异,无并发症。作者想强调定期TGDC和甲状腺随访对于通过临床检查和超声早期发现和诊断甲状腺恶性肿瘤的重要性。
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引用次数: 0
Delayed-Onset Neuropathic Pain after Septoplasty. 鼻中隔成形术后的延迟性神经性疼痛。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-12-22 eCollection Date: 2021-01-01 DOI: 10.1155/2021/9966318
Foteini-Stefania Koumpa, Mark Ferguson, Hesham Saleh

Postoperative pain following a septoplasty is expected to be mild and limited to a few days after the operation. Chronic pain following the procedure is rare. No cases of delayed-onset neuropathic pain or allodynia have been described in the literature. This paper presents a case of delayed-onset neuropathic pain after septoplasty in a previously pain-free asthmatic patient that was successfully managed by administration of intranasal local anaesthesia. Physical examination and imaging excluded any other cause of neuralgia. A literature review revealed reports of chronic pain in patients following septoplasty if there were nasal contact or compression points or nasal tumours. Separately, acute postseptoplasty allodynia is documented in iatrogenic maxillary nerve damage. However, delayed-onset neuralgic pain, exacerbated by certain environmental triggers, has not been previously described. Facial pain can be debilitating; successfully managing this neuralgic pain with administration of intranasal local anaesthetic had a substantial effect on the patient's quality of life.

鼻中隔成形术后的术后疼痛预计是轻微的,并限制在手术后几天。手术后的慢性疼痛是罕见的。文献中没有迟发性神经性疼痛或异常性疼痛的病例。这篇论文提出了一个延迟发作神经性疼痛后的鼻中隔成形术在一个以前无痛的哮喘患者成功地管理管理的鼻内局部麻醉。体格检查和影像学检查排除了任何其他神经痛的原因。一篇文献综述揭示了鼻中隔成形术后患者慢性疼痛的报告,如果有鼻接触或压迫点或鼻肿瘤。另外,急性鼻中隔成形术后异常痛症在医源性上颌神经损伤中也有记载。然而,延迟性神经痛,某些环境诱因加剧,以前没有描述。面部疼痛会使人虚弱;成功地管理这种神经痛与鼻内局部麻醉的管理对患者的生活质量有实质性的影响。
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引用次数: 0
A Rare Complication of Fine-Needle Aspiration of Neck Structures. 颈部结构细针抽吸的罕见并发症。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-12-15 eCollection Date: 2021-01-01 DOI: 10.1155/2021/8944119
Yazeed M Qadadha, Nainika Nanda, Chad Ennis, Timothy McCulloch

Fine-needle aspiration (FNA) is a generally accepted tool for safe diagnostic evaluation in the workup of lesions and masses. Aside from the commonly discussed risks of infection and minor bleeding related to skin puncture, other more serious complications have been reported sparingly. We present two cases of pneumothorax from FNA of neck structures, which have been theorized but not previously reported to our knowledge. Discussion of cases of this complication rather than solely a theoretical understanding of it will aid in diagnosis and management of this complication.

细针穿刺(FNA)是一种普遍接受的工具,用于安全的诊断评估病变和肿块的工作。除了经常讨论的感染风险和与皮肤穿刺有关的轻微出血外,其他更严重的并发症很少有报道。我们提出了两例由颈部结构的FNA引起的气胸,这是理论性的,但据我们所知,以前没有报道过。讨论这种并发症的病例,而不仅仅是理论上的理解,将有助于这种并发症的诊断和管理。
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引用次数: 0
Importance of Imaging in Congenital Unilateral Vocal Fold Paralysis: A Case of Neck Neuroblastoma Presenting with Unilateral Vocal Fold Paralysis. 影像学在先天性单侧声带麻痹中的重要性:一例颈部神经母细胞瘤表现为单侧声带麻痹。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-12-06 eCollection Date: 2021-01-01 DOI: 10.1155/2021/7368567
W X Yeo, C Y Chan, K K H Tan

Congenital vocal fold paralysis (VFP) is an important cause of respiratory compromise in infants. It can either be unilateral or bilateral, while imaging is routinely performed for bilateral VFP to evaluate for potential neurological causes, and such a practice may not be routine for unilateral VFP. While many of the unilateral VFP cases are idiopathic, the cause may occasionally be more sinister in nature, such as tumors. Therefore, unless an obvious cause of unilateral VFP is present (such as cardiac surgery or birth trauma), routine imaging of the brain, neck, and mediastinum should be performed for congenital unilateral VFP. We describe a rare case of a cervical neuroblastoma presenting with unilateral VFP that was detected only on imaging, thus highlighting its value and importance.

先天性声带麻痹(VFP)是导致婴幼儿呼吸系统损伤的重要原因。它可以是单侧或双侧,而成像是常规的双侧VFP,以评估潜在的神经系统原因,这种做法可能不是单侧VFP的常规做法。虽然许多单侧VFP病例是特发性的,但有时病因可能更险恶,如肿瘤。因此,除非存在单侧VFP的明显原因(如心脏手术或出生创伤),否则应对先天性单侧VFP进行常规脑、颈部和纵隔成像。我们描述了一个罕见的宫颈神经母细胞瘤表现为单侧VFP,仅在影像学上被检测到,从而强调其价值和重要性。
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引用次数: 0
Bilateral Recurrent Laryngeal Nerve Palsy following Total Thyroidectomy in Triple A Syndrome, an Unexpected but Critical Complication. 全甲状腺切除术后双侧喉返神经麻痹的三重A综合征,一个意想不到的但关键的并发症。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-11-19 eCollection Date: 2021-01-01 DOI: 10.1155/2021/1315117
Mathieu Chamberland, Marc-Antoine Poulin, Danielle Beaudoin

Introduction: Triple "A" syndrome (TAS) is a rare autosomal recessive disorder that presents in childhood with achalasia cardia, alacrima, ACTH-resistant adrenal insufficiency, with sensorimotor and autonomic polyneuropathy developing later in the course of the disease. Case Presentation. An adult white male affected by this syndrome underwent an uneventful total thyroidectomy for malignancy and suffered delayed bilateral recurrent laryngeal nerve palsy in the early postoperative hours. The palsy spontaneously resolved after a five-week course.

Conclusion: Given the rarity of this severe condition and the absence of surgical or medical causes identifiable, there is possibility that it is the neurological involvement caused by TAS that predisposed the patient to this adverse outcome, precipitated by standard manipulations during surgery.

简介:三“A”综合征(TAS)是一种罕见的常染色体隐性遗传病,儿童期表现为贲门失弛缓症、肺水肿、acth抵抗性肾上腺功能不全,在病程后期出现感觉运动和自主神经病变。案例演示。一个成年白人男性受此综合征的影响,接受了良性甲状腺全切除术,术后早期遭受延迟性双侧喉返神经麻痹。经过五周的治疗,麻痹自行消退。结论:鉴于这种严重疾病的罕见性和缺乏可识别的外科或医学原因,有可能是由TAS引起的神经系统受累使患者易患这种不良结果,并在手术期间通过标准操作引起。
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引用次数: 0
INI1-Intact Sinonasal Carcinoma with Rhabdoid Features. 完整鼻窦癌伴横纹肌样特征。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-11-18 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6075130
Erin Mulry, Danielle M Blake, Poornima Hegde, Todd E Falcone

Sinonasal malignancies are known for their associated poor prognosis and diversity of histologic features. While poor prognosis is largely due to advanced disease at presentation, histologic features also play a significant role. Therefore, accurate pathologic diagnosis is of utmost importance. Here, we describe a 63-year-old male with chronic left-sided nasal obstruction and left-sided epistaxis who was found to have a large mass occupying most of the nasal cavity extending through the nasopharynx to just below the nasopharyngeal surface of the soft palate. During surgical excision, the mass was noted to originate from the floor of the maxillary sinus with erosion of the medial wall of the maxillary sinus. Pathology revealed a diagnosis of INI1-intact poorly differentiated composite carcinoma with rhabdoid phenotype and sarcomatoid and squamous cell carcinoma foci arising within an inverted papilloma. Included in this report is a detailed description of both the patient's medical course and this pathologically novel sinonasal neoplasm. We aim to elucidate this rare tumor's complex features in order to improve future diagnosis and stimulate prospective research on sinonasal malignancies with complex histology.

鼻窦恶性肿瘤以其预后差和组织学特征的多样性而闻名。虽然预后不良主要是由于疾病晚期,但组织学特征也起着重要作用。因此,准确的病理诊断至关重要。在这里,我们描述了一个63岁的男性慢性左侧鼻塞和左侧鼻出血,他被发现有一个很大的肿块占据了大部分鼻腔,穿过鼻咽部延伸到鼻咽部软腭表面的下方。在手术切除时,发现肿块起源于上颌窦底部,并侵蚀上颌窦内侧壁。病理诊断为ini1完整的低分化复合型癌,横纹肌样表型,肉瘤样癌和鳞状细胞癌灶出现在倒置乳头状瘤内。包括在这个报告是一个详细的描述,这两个病人的医疗过程和病理新颖的鼻窦肿瘤。我们的目的是阐明这种罕见肿瘤的复杂特征,以提高未来的诊断和促进对复杂组织学的鼻窦恶性肿瘤的前瞻性研究。
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引用次数: 0
ALK-Positive Anaplastic Large Cell Lymphoma: A Diagnostic Dilemma for the Otolaryngologist in a Resource Poor Setting. alk阳性间变性大细胞淋巴瘤:一个诊断困境的耳鼻喉科医生在资源贫乏的设置。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-11-01 eCollection Date: 2021-01-01 DOI: 10.1155/2021/3756742
Nicholas Figaro, Rickhi Ramoutar, Rodolfo Arozarena, Dawn Meyers, Solaiman Juman

Anaplastic large cell lymphoma is a rare subtype of non-Hodgkin's lymphoma. The morphological diversity with which its anaplastic cells confer make the diagnosis of this hematological entity extremely challenging to the pathologist in a resource poor setting. We present a case of a 35-year-old male with a nasopharyngeal mass and cervical lymphadenopathy and the adversities faced by out otolaryngology department with obtaining the diagnosis of ALK-positive anaplastic large cell lymphoma.

间变性大细胞淋巴瘤是一种罕见的非霍奇金淋巴瘤亚型。其间变性细胞赋予的形态多样性使这种血液学实体的诊断在资源贫乏的情况下对病理学家极具挑战性。我们报告一个35岁男性鼻咽肿块及颈部淋巴结肿大的病例,以及耳鼻喉科在获得alk阳性间变性大细胞淋巴瘤诊断时所面临的困难。
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引用次数: 0
Alobar Holoprosencephaly with Cebocephaly in a Neonate Born to an HIV-Positive Mother in Eastern Uganda. 乌干达东部一名艾滋病毒阳性母亲所生的新生儿无前脑畸形伴头畸形。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-10-25 eCollection Date: 2021-01-01 DOI: 10.1155/2021/7282283
Franck Katembo Sikakulya, Sonye Magugu Kiyaka, Robert Masereka, Robinson Ssebuufu

Background: Holoprosencephaly (HPE) is a rare cerebrofacial abnormality resulting from the complete or partial failure of the diverticulation and cleavage of the primitive forebrain. It has an incidence at birth of 1:16000. Case Presentation. We report a case of a 2600 g newborn female delivered by an HIV-infected mother in whom an antenatal ultrasound scan at 34 weeks' gestation reported features of fetal alobar holoprosencephaly. The neonate was born with cebocephaly, a monkey-like head, and did not survive for more than 30 minutes following delivery by caesarian section despite oxygen therapy.

Conclusion: Alobar HPE with cebocephaly remains incompatible with life. In this resource-limited setting, the diagnosis was made clinically, and only an ultrasound scan was performed to confirm the diagnosis. Chromosomal analysis could have given more information.

背景:全前脑畸形(HPE)是一种罕见的脑面部异常,由原始前脑的憩室和卵裂完全或部分失败引起。它在出生时的发病率是1:16000。案例演示。我们报告了一个2600克的新生儿由艾滋病毒感染的母亲分娩的情况下,产前超声扫描在妊娠34周报告胎儿无前脑畸形的特征。这名新生儿出生时就有头畸形,长得像猴子的头,尽管进行了氧气治疗,但在剖腹产后没有存活超过30分钟。结论:Alobar型HPE伴头畸形仍与生活不相容。在这种资源有限的情况下,诊断是在临床上做出的,只有超声扫描来确认诊断。染色体分析可以提供更多的信息。
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引用次数: 3
Deep Neck Infection: Atypical Presentation of Papillary Thyroid Cancer. 深颈部感染:甲状腺乳头状癌的不典型表现。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-10-18 eCollection Date: 2021-01-01 DOI: 10.1155/2021/1479201
Apichana Mahattanapreut, Rangsima Aroonroch, Chalermchai Chintrakarn, Chutintorn Sriphrapradang

Deep neck infection is defined as an infectious process in the potential spaces and fascial plane of the neck which may result in a fatal complication. Prompt drainage and broad-spectrum antibiotics are the mainstays of treatment. Deep neck infection as the initial presentation of primary head and neck cancer is not common. Nevertheless, head and neck squamous cell carcinoma is the most common primary head and neck cancer, which could present with cervical metastasis and subsequently becomes infected. Papillary thyroid cancer has a naturally indolent course, and most patients present with a thyroid nodule. However, deep neck infection could be an uncommon presentation of papillary thyroid cancer which may obscure the diagnosis of underlying malignancy. This case report aims to present a rare presentation of papillary thyroid cancer which needs meticulous evaluation. Moreover, the pathological examination should be performed in all cases of deep neck infection for early detection and management of underlying papillary thyroid cancer.

深颈部感染是指颈部潜在间隙和筋膜平面的感染过程,可导致致命的并发症。及时引流和广谱抗生素是治疗的主要手段。深颈部感染作为原发性头颈部癌的最初表现并不常见。然而,头颈部鳞状细胞癌是最常见的原发性头颈部癌症,它可能出现宫颈转移,随后发生感染。甲状腺乳头状癌病程自然无痛,多数患者表现为甲状腺结节。然而,深颈部感染可能是一种罕见的乳头状甲状腺癌的表现,这可能会掩盖潜在恶性肿瘤的诊断。本病例报告的目的是提出一个罕见的表现乳头状甲状腺癌,需要细致的评估。此外,所有深颈部感染病例都应进行病理检查,以便早期发现和处理潜在的甲状腺乳头状癌。
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引用次数: 1
A Case of Nasopharyngeal Mycobacteriosis with Bony Erosion of the External Skull Base. 鼻咽分枝杆菌病合并外颅底骨侵蚀1例。
IF 0.6 Q4 OTORHINOLARYNGOLOGY Pub Date : 2021-10-15 eCollection Date: 2021-01-01 DOI: 10.1155/2021/7500273
Kohei Matsuo, Satoshi Tanaka, Masayuki Sakata, Hiroki Takeda, Akihiro Nagata, Masashi Mori, Rie Ito, Yoshifumi Yamamoto, Kiyonobu Ueno, Atsuhiko Uno

Primary nasopharyngeal mycobacteriosis is a rare disease. We present a case in which skull base bone erosion appeared and was alleviated during the course of the treatment. Bone complications occur in osteoarticular mycobacteriosis, but their occurrence in primary nasopharyngeal mycobacteriosis has not been reported. A 77-year-old immunocompromised Asian woman presented with a right occipitotemporal headache. An ulcerative mass covered with a thick yellowish discharge was found in the roof and posterior walls of the right nasopharynx. Because histopathological examination indicated the presence of mycobacterial infection, we began using antituberculosis medication for the treatment because of the possibility of primary nasopharyngeal tuberculosis. However, this was followed by glossopharyngeal and vagus nerve paralysis. Computed tomography (CT) showed a diffuse enhancing mucosal irregularity in the nasopharynx with bony erosion of the external skull base. Deep tissue biopsy was repeated to differentiate it from malignant lesions, and drainage of pus from the right nasopharynx was confirmed. Subsequently, the headache, neurological findings, and the yellowish discharge disappeared, and the bony erosion of the external skull base was alleviated. Surgical intervention should also be considered for drug-resistant mycobacteriosis. We concluded that mycobacteriosis should also be considered apart from carcinoma even if CT shows a diffuse enhancing mucosal irregularity with bone destruction in the nasopharynx.

原发性鼻咽分枝杆菌病是一种罕见的疾病。我们提出一个病例,其中颅底骨侵蚀出现,并在治疗过程中得到缓解。骨并发症发生在骨关节分枝杆菌病,但其发生在原发性鼻咽分枝杆菌病尚未见报道。77岁免疫功能低下的亚洲女性表现为右侧枕颞头痛。在右鼻咽顶部和后壁发现一溃疡性肿块,上面有厚的淡黄色分泌物。由于组织病理学检查显示存在分枝杆菌感染,我们开始使用抗结核药物进行治疗,因为可能是原发性鼻咽结核。然而,紧随其后的是舌咽神经和迷走神经麻痹。计算机断层扫描(CT)显示鼻咽部弥漫性强化粘膜不规则,外颅底骨侵蚀。反复进行深部组织活检以鉴别其与恶性病变,并证实右侧鼻咽部有脓渗出。随后,头痛、神经学症状和淡黄色分泌物消失,外颅底骨侵蚀减轻。对于耐药分枝杆菌病也应考虑手术干预。我们的结论是,即使CT显示鼻咽部弥漫性强化粘膜不规则并伴有骨破坏,也应考虑分枝杆菌病。
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引用次数: 0
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Case Reports in Otolaryngology
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