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Current Colorectal Cancer Reports最新文献

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What Rectal Cancer Patients May Be Able to Safely Avoid Radiation? 哪些直肠癌患者可以安全地避免放疗?
Q3 Medicine
Current Colorectal Cancer Reports
Pub Date : 2022-12-01 DOI: 10.1007/s11888-022-00480-3
D. Dickstein, M. Buckstein
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引用次数: 0
Emerging Role of Brachytherapy in the Non-operative Management of Rectal Cancer 近距离放疗在直肠癌非手术治疗中的新作用
Q3 Medicine
Current Colorectal Cancer Reports
Pub Date : 2022-11-11 DOI: 10.1007/s11888-022-00479-w
Samuel C. Zhang, K. M. Atkins, E. M. Chung, M. Kamrava
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引用次数: 1
Local Therapies for Colorectal Cancer Oligometastases to the Lung 结直肠癌肺少转移的局部治疗
Q3 Medicine
Current Colorectal Cancer Reports
Pub Date : 2022-06-10 DOI: 10.1007/s11888-022-00477-y
E. M. Chung, J. Gong, K. Zaghiyan, M. Kamrava, K. Atkins
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引用次数: 0
Surgical Management of Metastatic Colorectal Cancer 转移性结直肠癌的外科治疗
Q3 Medicine
Current Colorectal Cancer Reports
Pub Date : 2022-04-18 DOI: 10.1007/s11888-022-00476-z
Babak Mohammadian, Clay D King, T. Schmitt, S. Kumer
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引用次数: 0
Current Updates on HER2–Directed Therapies in Metastatic Colorectal Cancer her2定向治疗转移性结直肠癌的最新进展
Q3 Medicine
Current Colorectal Cancer Reports
Pub Date : 2022-04-01 DOI: 10.1007/s11888-022-00475-0
Maria G. Fencer, C. Davis, K. Spencer
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引用次数: 0
Liver-Directed Therapy for Metastatic Colon Cancer: Update 转移性结肠癌癌症的肝导向治疗：最新进展
Q3 Medicine
Current Colorectal Cancer Reports
Pub Date : 2022-02-01 DOI: 10.1007/s11888-022-00474-1
John J. Waddell, Patricia H. Townsend, Z. Collins, C. Walter
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引用次数: 0
Intracorporeal Versus Extracorporeal Anastomosis in Laparoscopic Colectomy: A Meta-Analysis and Systematic Review 腹腔镜结肠切除术中体内与体外吻合的Meta分析和系统评价
Q3 Medicine
Current Colorectal Cancer Reports
Pub Date : 2022-02-01 DOI: 10.1007/s11888-022-00473-2
Timothy Jia Rong Lam, Shamill Amedot Udonwa, C. Yaow, K. R. Y. Nistala, C. Chong
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引用次数: 1
Toxicity Management in the Era of Changing Treatment Paradigms for Locally Advanced Rectal Cancer. 局部晚期直肠癌治疗模式转变时代的毒性管理。
Q3 Medicine
Current Colorectal Cancer Reports
Pub Date : 2022-01-01 Epub Date: 2022-11-07 DOI: 10.1007/s11888-022-00478-x
Anjalika R Kumar, Nina N Sanford

Purpose of review: Treatment paradigms for locally advanced rectal cancer have evolved over the last several decades. Patients now have several different "standard" options with different radiation courses, sequencing of treatment modality and in some scenarios potentially avoidance of surgery. In this context, an updated understanding of treatment toxicity is needed to help patients make informed decision regarding their treatment.

Recent findings: The RAPIDO study showed no difference in cumulative rate or grade of toxicity between short and long course radiation. Based upon our experience, patients with short course radiation tend to present with acute symptoms 1-2 weeks after completion of radiation, while those receiving long course chemoradiation have symptoms towards the end of treatment. Treatments that may be helpful particularly for short course radiation toxicity include Bentyl (dicycloverine) and steroids.

Summary: The most common toxicities from radiation are due to bowel and rectal inflammation leading to diarrhea, cramping, and urgency. The combination of surgery and radiation can exacerbate these symptoms. The most common late toxicity in patients receiving doublet chemotherapy is neurotoxicity. Rates of infertility differ in men versus women; all efforts for fertility preservation should be completed prior to initiation of any therapy.

回顾的目的:局部晚期直肠癌的治疗模式在过去的几十年里发生了变化。患者现在有几种不同的“标准”选择，有不同的放射疗程、治疗方式的顺序，在某些情况下可能避免手术。在这种情况下，需要对治疗毒性有一个最新的认识，以帮助患者对他们的治疗做出明智的决定。最近的发现:RAPIDO研究显示短期和长期放射的累积率和毒性等级没有差异。根据我们的经验，接受短疗程放疗的患者往往在放疗结束后1-2周出现急性症状，而接受长疗程放化疗的患者在治疗结束时出现症状。治疗可能有帮助，特别是对短期放射毒性包括苯基(双环草碱)和类固醇。总结:最常见的辐射毒性是由于肠道和直肠炎症导致腹泻、痉挛和尿急。手术和放疗相结合会加重这些症状。在接受双重化疗的患者中，最常见的晚期毒性是神经毒性。男性和女性的不孕率不同;在开始任何治疗之前，应完成所有保存生育能力的努力。
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引用次数: 3
The Role of Ablative Radiotherapy to Liver Oligometastases from Colorectal Cancer 消融放疗在结直肠癌肝少转移中的作用
Q3 Medicine
Current Colorectal Cancer Reports
Pub Date : 2021-12-01 DOI: 10.1007/s11888-021-00472-9
E. Ku, J. Yeakel, M. Gan, F. Ahmed, J. Harris, J. Kuo, R. Wolf, Dayantha M. Fernando, S. Seyedin
{"title":"The Role of Ablative Radiotherapy to Liver Oligometastases from Colorectal Cancer","authors":"E. Ku, J. Yeakel, M. Gan, F. Ahmed, J. Harris, J. Kuo, R. Wolf, Dayantha M. Fernando, S. Seyedin","doi":"10.1007/s11888-021-00472-9","DOIUrl":"https://doi.org/10.1007/s11888-021-00472-9","url":null,"abstract":"","PeriodicalId":45986,"journal":{"name":"Current Colorectal Cancer Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"53096521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Imaging Advances on CT and MRI in Colorectal Cancer 癌症结直肠癌的CT和MRI影像学研究进展
Q3 Medicine
Current Colorectal Cancer Reports
Pub Date : 2021-12-01 DOI: 10.1007/s11888-021-00468-5
R. García-Figueiras, S. Baleato-González, M. Canedo-Antelo, Lidia Alcalá, A. Marhuenda
{"title":"Imaging Advances on CT and MRI in Colorectal Cancer","authors":"R. García-Figueiras, S. Baleato-González, M. Canedo-Antelo, Lidia Alcalá, A. Marhuenda","doi":"10.1007/s11888-021-00468-5","DOIUrl":"https://doi.org/10.1007/s11888-021-00468-5","url":null,"abstract":"","PeriodicalId":45986,"journal":{"name":"Current Colorectal Cancer Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43476318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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