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Low level laser therapy and rheumatoid arthritis: a systematic review and meta-analysis study. 低水平激光疗法与类风湿性关节炎:系统回顾与荟萃分析研究。
IF 1.8 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Pub Date : 2024-11-21 DOI: 10.4081/ejtm.2024.13107
Amirali Salajegheh, Fatemeh Yazdi Yahyaabadi, Farzaneh Yazdi

This systematic review and meta-analysis aimed to evaluate the efficacy of Low-Level Laser Therapy (LLLT) in the treatment of Rheumatoid Arthritis (RA), focusing on its effects on pain relief, grip strength, and morning stiffness. A comprehensive search was conducted across PubMed, Scopus, and Web of Science, yielding 3,111 articles. After eliminating duplicates and screening titles and abstracts, 94 full-text articles were assessed, and 23 studies met the eligibility criteria for inclusion in the systematic review. Of these, 22 studies were included in the meta-analysis. Data were extracted and analyzed using a random-effects model, with pooled Mean Differences (MD) calculated for the primary outcomes. The meta-analysis revealed that LLLT did not significantly reduce pain compared to placebo (MD = 0.00, 95% CI [-0.09, 0.09], p = 0.97). However, LLLT significantly improved grip strength (MD = -12.38, 95% CI [-17.42, -7.34], p < 0.01) and reduced morning stiffness (MD = -0.84, 95% CI [-1.33, -0.36], p < 0.01), despite substantial heterogeneity in these outcomes. LLLT shows promise in improving grip strength and reducing morning stiffness in RA patients, though it does not significantly impact pain relief. These findings highlight the potential role of LLLT as an adjunctive treatment for RA, with further research needed to optimize treatment protocols and clarify underlying mechanisms.

本系统综述和荟萃分析旨在评估低强度激光疗法(LLLT)治疗类风湿性关节炎(RA)的疗效,重点关注其对疼痛缓解、握力和晨僵的影响。我们在 PubMed、Scopus 和 Web of Science 上进行了全面搜索,共搜索到 3,111 篇文章。在剔除重复文章、筛选标题和摘要后,评估了 94 篇全文文章,有 23 项研究符合纳入系统综述的资格标准。其中,22 项研究被纳入荟萃分析。采用随机效应模型提取和分析数据,并计算主要结果的集合平均差(MD)。荟萃分析表明,与安慰剂相比,LLLT 并未显著减轻疼痛(MD = 0.00,95% CI [-0.09, 0.09],P = 0.97)。不过,LLLT 能明显改善握力(MD = -12.38,95% CI [-17.42,-7.34],p <0.01)并降低晨僵程度(MD = -0.84,95% CI [-1.33,-0.36],p <0.01),尽管这些结果存在很大的异质性。LLLT在改善RA患者的握力和减轻晨僵方面显示出前景,尽管它对疼痛缓解没有显著影响。这些研究结果突显了 LLLT 作为 RA 辅助治疗的潜在作用,但还需要进一步的研究来优化治疗方案并阐明其潜在机制。
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引用次数: 0
Vitamin D receptor gene polymorphisms in patients with relapsing multiple sclerosis. 复发性多发性硬化症患者的维生素 D 受体基因多态性。
IF 1.8 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Pub Date : 2024-11-21 DOI: 10.4081/ejtm.2024.12993
Maryam Milanifard, Soraya Mehrabi, Reza Ahadi, Mohsen Nabiuni, Samaneh Azimi Souteh, Mohammad Taghi Joghataei

The relationship between the vitamin D receptor (VDR) gene and many pathogenic pathways in relapsing-remitting multiple sclerosis (RRMS) remains unclear. Given the significance of the topic, we conducted this study to explore the correlation between vitamin D receptor gene polymorphisms and clinical and inflammatory factors in patients suffering from relapsing-remitting multiple sclerosis. The current research is a case/control study conducted based on the Helsinki Ethical Principles. RRMS disease was confirmed based on history, clinical symptoms, radiological signs and neurologist diagnosis. The research population consisted of healthy people and patients with RRMS who were referred to Hazrat Rasool Akram Hospital between 2021 and 2023. For each person participating in the study (RRMS patient and healthy), five milliliters of peripheral blood containing the anticoagulant EDTA was collected. Polymerase chain reaction was performed using two specific and appropriate oligonucleotide primers. The restriction fragment length polymorphism technique was used, one of the standard methods for identifying polymorphisms. Statistical analysis was performed using SPSS software version 23. The odds ratio and 95% confidence limits were calculated. The SNP Analyzer software was used to analyze the allele frequency of each polymorphism in healthy and RRMS individuals and compare the values. Prism version 5 software was used to draw diagrams. In the present study, a statistically significant difference was observed between the percentage of FokI genotypes in RRMS patients and healthy individuals. FokI polymorphism showed a significantly increased risk with an odds ratio of 7.28 in patients with the FF genotype compared to healthy individuals. ApaI, TaqI, and BsmI were not significantly different between the two groups. Based on the findings of the present study, FokI polymorphism showed a significant risk increase in RRMS patients with FF genotype compared to healthy individuals.

维生素 D 受体(VDR)基因与复发性多发性硬化症(RRMS)的多种致病途径之间的关系仍不清楚。鉴于该课题的重要性,我们开展了这项研究,以探讨复发性多发性硬化症患者体内维生素 D 受体基因多态性与临床和炎症因素之间的相关性。本研究是根据赫尔辛基伦理原则进行的病例/对照研究。根据病史、临床症状、放射学体征和神经科医生的诊断确认为复发性多发性硬化症。研究对象包括 2021 年至 2023 年期间转诊到 Hazrat Rasool Akram 医院的健康人和 RRMS 患者。参加研究的每个人(RRMS 患者和健康人)都要采集 5 毫升含有抗凝剂 EDTA 的外周血。聚合酶链反应使用两种特异性和适当的寡核苷酸引物进行。限制性片段长度多态性技术是鉴定多态性的标准方法之一。统计分析使用 SPSS 软件 23 版进行。计算了几率比例和 95% 的置信区间。使用 SNP Analyzer 软件分析健康人和 RRMS 患者中每种多态性的等位基因频率,并对数值进行比较。使用 Prism 5 版软件绘制图表。本研究观察到,RRMS 患者和健康人的 FokI 基因型比例存在显著统计学差异。FokI多态性显示,与健康人相比,FF基因型患者的风险明显增加,几率比为7.28。ApaI、TaqI和BsmI在两组之间没有明显差异。根据本研究的结果,与健康人相比,FF 基因型 RRMS 患者的 FokI 多态性风险明显增加。
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引用次数: 0
Efficacy of electrical stimulation of the zygomaticus muscle in complete facial paralysis: evidence from facial grading and automated image analysis. 电刺激颧肌对完全性面瘫的疗效:面部分级和自动图像分析的证据。
IF 1.8 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Pub Date : 2024-11-15 DOI: 10.4081/ejtm.2024.13161
Johannes Krauß, Gabriel Meincke, Maren Geitner, Anna-Maria Kuttenreich, Jan Beckmann, Dirk Arnold, Jonas Ballmaier, Thomas Lehmann, Winfried Mayr, Orlando Guntinas-Lichius, Gerd Fabian Volk

Surface Functional Electrical Stimulation (FES) is a well-studied intervention for multiple muscular disorders. However, it is still controversially discussed as a complementary therapy for complete facial paralysis. The aim of this intervention is to test a daily home-based ES concept as a pilot study regarding safety, feasibility, and effects on facial functionality and symmetry. In a prospective single-centre pilot study, 10 patients (median 61 years, denervation 130 d) with complete peripheral facial paralysis performed home-based FES of the affected lateral mouth region Stimulation parameters, facial paralysis scores and standardised photographs were assessed in monthly follow-ups. No serious adverse events appeared. Stimulation parameters could be constantly increased indicating effective muscle training while subjectively perceived functionality of the face improved. Thus, smile angle of the paralysed side improved as well. FES is a safe therapy model for application in facial nerve paralysis patients. A feasible stimulation protocol could be applied, which improved the functionality and symmetry of the stimulated facial region. A future controlled, randomised and double-blind follow-up study is needed to investigate these initial results in a further evolved replicable setting.

表面功能性电刺激(FES)是一种经过充分研究的治疗多种肌肉疾病的干预方法。然而,将其作为治疗完全性面瘫的辅助疗法仍存在争议。这项干预措施的目的是测试日常家用 ES 概念的安全性、可行性以及对面部功能和对称性的影响。在一项前瞻性的单中心试点研究中,10 名患有完全性周围性面瘫的患者(中位数 61 岁,去神经130 天)在家中对受影响的侧口区域进行了电刺激治疗,并在每月的随访中对刺激参数、面瘫评分和标准化照片进行了评估。未出现严重不良事件。刺激参数可持续增加,表明肌肉训练有效,同时主观感觉面部功能有所改善。因此,瘫痪一侧的微笑角度也得到了改善。FES 是一种安全的治疗模式,适用于面神经麻痹患者。可行的刺激方案可以改善受刺激面部区域的功能和对称性。今后需要进行对照、随机和双盲跟踪研究,以便在进一步发展的可复制环境中对这些初步结果进行调查。
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引用次数: 0
Deceleration of denervated facial muscle atrophy through functional electrical stimulation: a sonographic quantification in patients with facial nerve paralysis. 通过功能性电刺激减缓失去神经支配的面肌萎缩:面神经麻痹患者的声学量化。
IF 1.8 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Pub Date : 2024-11-13 DOI: 10.4081/ejtm.2024.13162
Gabriel Meincke, Johannes Krauß, Maren Geitner, Anna-Maria Kuttenreich, Dirk Arnold, Jonas Ballmaier, Thomas Lehmann, Winfried Mayr, Orlando Guntinas-Lichius, Gerd Fabian Volk

Functional Electrical Stimulation (FES) is an established intervention for a range of muscular and neurological disorders that has already been studied in numerous publications. However, its application to Peripheral Facial nerve Paralysis (PFP) still needs to be sufficiently investigated. As the first approach known to the authors, this study examines the effect of FES on the facial muscles in complete PFP using ultrasonography as a means of observation. In a prospective single-center observational pilot study, ten patients with complete PFP, confirmed by needle-electromyography (EMG), performed FES of the affected lateral mouth region at home twice daily for 20 minutes. The facial muscles' Cross-Sectional Area (CSA) was regularly assessed using sonographic quantification. While the CSA of most non-stimulated muscles decreased considerably during ongoing paralysis, a significant CSA increase of the Zygomaticus Muscle (ZYG), which was regularly subjected to FES, could be demonstrated. FES can halt the atrophy of denervated ZYG and potentially other facial muscles. Further investigations with a more significant patient collective are recommended. From now on, FES could be established as an additive method in the non-invasive treatment of PFP.

功能性电刺激(FES)是一种治疗一系列肌肉和神经疾病的成熟干预方法,已有大量文献对其进行了研究。然而,它在周围性面神经麻痹(PFP)中的应用仍有待充分研究。作为作者所知的第一种方法,本研究使用超声波成像作为观察手段,研究了 FES 对完全性面神经麻痹患者面部肌肉的影响。在一项前瞻性单中心观察试验研究中,10 名经针刺肌电图(EMG)确认的完全性 PFP 患者在家中对受影响的侧口区域进行了 FES 治疗,每天两次,每次 20 分钟。面部肌肉的横截面积(CSA)通过超声波定量定期进行评估。在持续瘫痪期间,大多数非受刺激肌肉的CSA显著下降,但定期接受FES治疗的颧骨肌(ZYG)的CSA显著增加。FES 可以阻止失去神经支配的颧骨肌以及其他面部肌肉的萎缩。建议对更多患者进行进一步研究。从现在起,FES 可作为一种非侵入性治疗 PFP 的辅助方法。
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引用次数: 0
Obsessive-compulsive disorder, major depressive disorder, and addiction: the vicious relationship. 强迫症、重度抑郁症和成瘾:恶性关系。
IF 1.8 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Pub Date : 2024-11-13 DOI: 10.4081/ejtm.2024.13108
Rifaat S El-Mallakh, Jamal Shams, Moein Doroodgar, Masoud Doroodgar

Obsessive-Compulsive Disorder (OCD) and Major Depressive Disorder (MDD) are prevalent psychiatric conditions, each affecting a substantial portion of the global population. When these conditions coexist with a Substance Use Disorder (SUD), the complexity of the clinical presentation is heightened. Herein, we describe two cases of individuals who have comorbid OCD and/or MDD and substance use disorder that highlight the importance of addressing the coexisting psychiatric illness when treating the SUD. These cases highlight the importance of tailored, multidisciplinary care, offering a potential therapeutic strategy based on medications for comprehensive recovery in individuals facing complex comorbid disorders. An integrated treatment approach, encompassing both psychiatric and substance treatment perspectives, is imperative.

强迫症(OCD)和重度抑郁症(MDD)是普遍存在的精神疾病,各自影响着全球相当一部分人口。当这些疾病与药物使用障碍(SUD)同时存在时,临床表现的复杂性就会增加。在此,我们描述了两个合并有强迫症和/或多发性抑郁症和药物使用障碍的病例,强调了在治疗药物使用障碍时解决合并精神疾病问题的重要性。这些病例强调了量身定制的多学科护理的重要性,为面临复杂合并症的患者提供了一种基于药物的潜在治疗策略,以实现全面康复。当务之急是采取一种综合治疗方法,从精神病学和药物治疗两方面入手。
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引用次数: 0
Endocrine disorders in Kearns-Sayre syndrome with different severity of symptoms: two case reports and a literature review. 症状严重程度不同的卡恩斯-赛尔综合征内分泌失调:两份病例报告和文献综述。
IF 1.8 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Pub Date : 2024-10-30 DOI: 10.4081/ejtm.2024.12897
Ilya I Amergoolov, Yulia I Khruleva, Maria G Pavlova, Natalia V Likhodey, Abu M Sulaev, Elena V Surkova, Yulia P Sych, Marina F Kalashnikova, Anna S Arustamyan, Gratsinna A Martirosyan, Simione T Lew-Gor

Kearns-Sayre Syndrome (KSS) is a variant of mitochondrial disorder caused by a Mitochondrial Deoxyribonucleic Acid (mtDNA) deletion. Clinical manifestations of KSS can include different organ and system involvement. Different organ malfunctions, more often cardiac dysfunction, can lead to death. No effective treatment of this condition exists to date. Here, we report two patients with KSS. Female patient with a large-scale deletion of 7,020 base pairs (bp) suffered from hypogonadism, diabetes mellitus with fluctuating glucose levels, and had poor general health. A male patient with a common 4,977 bp deletion did not have diabetes mellitus but had impaired glucose tolerance. He also had a higher level of general health than our female patient. Both patients had reduced Bone Mineral Density (BMD). In female patients, calcium and vitamin D supplementation combined with metabolic therapy and nutritional drink supplements helped increase BMD (up to 32% in L1-L4). Comparing these two patients suggests that the larger the mtDNA deletion is, the more severe the course of the disease is. Not only does the size of the mtDNA deletion probably determine the severity of the disease, but also such factors as mtDNA heteroplasmy level, presence of mtDNA duplications, and pleioplasmy. Moreover, continuous nonconsecutive metabolic therapy and nutritional supplements are helpful in the prevention of deterioration of symptoms and general health.

卡恩斯-赛尔综合征(KSS)是线粒体脱氧核糖核酸(mtDNA)缺失引起的线粒体疾病的一种变异型。KSS 的临床表现可包括不同器官和系统的受累。不同器官的功能障碍(更常见的是心脏功能障碍)可导致死亡。迄今为止,尚无有效的治疗方法。在此,我们报告了两名 KSS 患者。女性患者的碱基对大范围缺失达 7,020 个,患有性腺功能减退症、糖尿病和血糖波动,全身健康状况较差。一名患有常见的 4 977 碱基对缺失的男性患者没有糖尿病,但糖耐量受损。他的一般健康水平也高于我们的女患者。这两名患者的骨密度(BMD)都有所降低。在女性患者中,钙和维生素 D 的补充与代谢疗法和营养饮料的补充相结合,有助于增加 BMD(L1-L4 达 32%)。对这两名患者进行比较表明,mtDNA缺失越大,病程就越严重。决定疾病严重程度的可能不仅是 mtDNA 缺失的大小,还有 mtDNA 异源水平、mtDNA 是否存在重复和多倍体等因素。此外,持续的非连续性代谢疗法和营养补充剂也有助于预防症状和总体健康状况的恶化。
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引用次数: 0
An aged-related structural study of DHPR tetrads in peripheral couplings of human skeletal muscle. 人体骨骼肌外周耦合中 DHPR 四元组的老化相关结构研究。
IF 1.8 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Pub Date : 2024-10-29 DOI: 10.4081/ejtm.2024.13273
Laura Pietrangelo, Rosa Mancinelli, Stefania Fulle, Simona Boncompagni

Among the numerous changes that occur in skeletal muscle during aging, the reduced regeneration potential after an injury is largely due to the impaired ability of satellite cells to proliferate and differentiate. Herein, using the freeze-fracture electron microscopy technique, we analyzed both the incidence and size of dihydropyridine receptors (DHPRs) tetrads (4 particles) in cultured myotubes from a young subject (28 years) after 9 days of differentiation and from an old subject (71 years) after 9 and 12 days of differentiation. Compared to young myotubes, at 9 days of differentiation old myotubes exhibited: i) a lower incidence and a smaller size of DHPR clusters and ii) a lower number of complete tetrads. At 12 days of differentiation values of incidence, size and number of complete tetrads in old myotubes were instead comparable with those of young myotubes at 9 days of differentiation. Collectively, these results indicate that in aged myotubes the synthesis process of the proteins involved in the excitation-contraction coupling mechanism, such as the DHPR, is somehow slowed, supporting previous studies evidence of a decrease in the differentiation potential of myotubes from elderly individuals.

在骨骼肌衰老过程中发生的众多变化中,受伤后再生潜力降低的主要原因是卫星细胞增殖和分化能力受损。在此,我们利用冷冻断裂电子显微镜技术,分析了年轻受试者(28 岁)的肌管在分化 9 天后和老年受试者(71 岁)的肌管在分化 9 天和 12 天后的二氢吡啶受体(DHPRs)四联体(4 个颗粒)的发生率和大小。与年轻肌管相比,在分化 9 天时,老年肌管表现出:i) 较低的 DHPR 群发生率和较小的 DHPR 群大小;ii) 较低的完整四聚体数量。在分化 12 天时,老肌管的发生率、大小和完整四聚体数量与分化 9 天时的年轻肌管相当。总之,这些结果表明,在老年肌管中,参与兴奋-收缩耦合机制的蛋白质(如DHPR)的合成过程在某种程度上减慢了,这也支持了之前关于老年肌管分化潜力下降的研究证据。
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引用次数: 0
Effectiveness of laser therapy among patients with open-angle glaucoma: a systematic review and meta-analysis study. 激光疗法对开角型青光眼患者的疗效:一项系统回顾和荟萃分析研究。
IF 16.4 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Pub Date : 2024-10-22 DOI: 10.4081/ejtm.2024.12931
Behzad Safarpour Lima, Shima Sayanjali

This study aims to evaluate the efficacy of selective laser trabeculoplasty in improving the intraocular pressure in patients diagnosed with open-angle glaucoma. A comprehensive search was performed across electronic databases, including PubMed, Scopus, and Web of Science, until June 2024, using keywords related to "selective laser trabeculoplasty" and "open-angle glaucoma." Studies were chosen based on set eligibility criteria. Data extraction was carried out by two independent reviewers, and statistical analyses were performed using a random-effects model to calculate the pooled mean differences in IOP reduction and overall success rates. The initial search yielded 3111 articles, with 23 studies included in the systematic review and 22 in the meta-analysis. The pooled MD in IOP reduction between the SLT and control groups was -1.44 mm Hg (95% CI: -2.19 to -0.70, p < 0.01). Subgroup analyses revealed a MD of -0.76 mm Hg (95% CI: -1.31 to -0.21, p < 0.01) when comparing SLT to medication, and -0.42 mm Hg (95% CI: -0.64 to -0.19, p < 0.01) when comparing 180-degree SLT to 360-degree SLT. The pooled success rate favored SLT with an odds ratio (OR) of 0.71 (95% CI: 0.51 to 0.99, p = 0.05). There was significant heterogeneity among the studies (I² = 71%). SLT is effective in lowering IOP in OAG patients, demonstrating significant efficacy compared to medication and different SLT protocols. The findings underscore SLT's potential as a reliable treatment option. However, the observed heterogeneity underscores the necessity for standardized protocols in future research to improve comparability and verify SLT's long-term effectiveness.

本研究旨在评估选择性激光小梁成形术对改善开角型青光眼患者眼压的疗效。在 2024 年 6 月之前,我们使用与 "选择性激光小梁成形术 "和 "开角型青光眼 "相关的关键词在 PubMed、Scopus 和 Web of Science 等电子数据库中进行了全面检索。根据设定的资格标准选择研究。数据提取由两名独立审稿人完成,并使用随机效应模型进行统计分析,计算出眼压降低率和总体成功率的汇总平均差异。初步检索共获得 3111 篇文章,其中 23 项研究被纳入系统综述,22 项研究被纳入荟萃分析。SLT组和对照组之间眼压降低的总平均值为-1.44 mm Hg(95% CI:-2.19 至-0.70,p < 0.01)。亚组分析显示,SLT 与药物治疗相比,MD 为-0.76 毫米汞柱(95% CI:-1.31 至 -0.21,p < 0.01);180 度 SLT 与 360 度 SLT 相比,MD 为-0.42 毫米汞柱(95% CI:-0.64 至 -0.19,p < 0.01)。SLT的成功率为0.71(95% CI:0.51-0.99,P = 0.05)。各研究之间存在明显的异质性(I² = 71%)。SLT能有效降低OAG患者的眼压,与药物治疗和不同的SLT方案相比,疗效显著。研究结果凸显了 SLT 作为一种可靠治疗方案的潜力。然而,观察到的异质性强调了未来研究中标准化方案的必要性,以提高可比性并验证 SLT 的长期有效性。
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引用次数: 0
Lower limb acute onset muscle pain: what do we have to look for? A case of isolated rupture of the rectus femoris. 下肢急性发作性肌肉疼痛:我们需要注意什么?一例孤立的股直肌断裂。
IF 1.8 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Pub Date : 2024-10-18 DOI: 10.4081/ejtm.2024.12846
Simona Portaro, Calogero Felice, Giulia Leonardi, Demetrio Milardi, Daniele Bruschetta, Danilo Leonetti, Eliseo Scarcella, Adriana Tisano, Angelo Alito

Acute muscle pain is muscle soreness that occurs during or within 24 hours of strenuous activity. Possible causes of acute muscle pain include localized muscle trauma, muscle tear, contusion with acute hemorrhage, or acute compartment syndrome. Isolated ruptures of the rectus femoris muscle are rare clinical conditions that result from excessive muscle strain following an abrupt contraction, incorrect movement, or sudden snap that exceeds the physiological limit of strain that the muscle can withstand. To date, there are few published reports evaluating the results of non-invasive treatment of such injuries. Herein, we report an unusual case of isolated distal rectus femoris tear in a 46-year-old female patient with no risk factors, who initially presented with extensor muscle weakness and pain and was treated conservatively with functional rest, physiotherapy, and cryotherapy.

急性肌肉疼痛是指在剧烈运动期间或 24 小时内出现的肌肉酸痛。急性肌肉疼痛的可能原因包括局部肌肉创伤、肌肉撕裂、急性出血挫伤或急性隔室综合征。股直肌孤立性断裂是一种罕见的临床病症,是由于肌肉突然收缩、不正确的运动或突然扣动后过度拉伸,超过了肌肉所能承受的生理极限。迄今为止,很少有公开报道对此类损伤的非侵入性治疗效果进行评估。在此,我们报告了一例不寻常的孤立性股直肌远端撕裂病例,患者是一名 46 岁的女性,无任何危险因素,最初表现为伸肌无力和疼痛,接受了功能性休息、理疗和冷冻疗法等保守治疗。
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引用次数: 0
Hand-grip strength in recreational downhill skiers: a comparison to normative reference values. 休闲下坡滑雪运动员的手握力:与标准参考值的比较。
IF 1.8 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Pub Date : 2024-10-17 DOI: 10.4081/ejtm.2024.13021
Johannes Burtscher, Barbara Strasser, Gerhard Ruedl, Elena Pocecco, Verena Menz, Marc Philippe, Martin Kopp, Martin Burtscher

Hand-grip strength was evaluated in 757 recreational downhill skiers and compared to 1021 community-dwellers. Findings are reported for age and sex categories consistent with community-dwelling norms. Effect size (Cohen's d) was calculated to estimate the clinical relevance of strength differences between populations. Most male and half of the female age categories of downhill skiers demonstrated higher grip strength of the dominant hand (moderate to large effect size) compared to the reference population. Hand-grip strength in skiers declined with age at a similar rate as in the reference population. Relative grip strength (per kg body mass) was significantly and positively correlated with physical activity (hours/week), and with the number of ski days per year, and negatively with body mass. Thus, hand-grip strength may be related to the type, volume and intensity of exercise regularly performed. These results can help to assess whether the individual hand-grip strength is above or below average with regard to the normal population and the skier population as well and will support advice for training and/or rehabilitation.

对 757 名休闲下坡滑雪者的手握力进行了评估,并与 1021 名社区居民进行了比较。报告了与社区居民标准一致的年龄和性别分类结果。通过计算效应大小(Cohen's d)来估计不同人群之间力量差异的临床相关性。与参照人群相比,大多数男性和半数女性年龄组的速降滑雪者的主导手握力较强(中等至较大的效应大小)。随着年龄的增长,滑雪者手部握力的下降速度与参照人群相似。相对握力(每公斤体重)与体力活动(每周小时数)和每年滑雪天数呈显著正相关,而与体重呈负相关。因此,手握力可能与经常进行的运动类型、运动量和运动强度有关。这些结果有助于评估个人的手握力是否高于或低于正常人群和滑雪人群的平均水平,并为训练和/或康复提供建议。
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引用次数: 0
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European Journal of Translational Myology
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