Pub Date : 2022-10-19DOI: 10.1007/s10663-022-09552-x
Elmar Dönnebrink, Nils Grevenbrock
{"title":"Sustainability gap of public debt: importance of interest rates and a new decomposition with premia","authors":"Elmar Dönnebrink, Nils Grevenbrock","doi":"10.1007/s10663-022-09552-x","DOIUrl":"https://doi.org/10.1007/s10663-022-09552-x","url":null,"abstract":"","PeriodicalId":46526,"journal":{"name":"Empirica","volume":"49 1","pages":"1009 - 1030"},"PeriodicalIF":1.3,"publicationDate":"2022-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42537447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"经济学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-15DOI: 10.1007/s10663-022-09551-y
M. Huber, Ann‑Marie Sommerfeld, Silke Uebelmesser
{"title":"Correction: Language learning: human capital investment or consumption?","authors":"M. Huber, Ann‑Marie Sommerfeld, Silke Uebelmesser","doi":"10.1007/s10663-022-09551-y","DOIUrl":"https://doi.org/10.1007/s10663-022-09551-y","url":null,"abstract":"","PeriodicalId":46526,"journal":{"name":"Empirica","volume":"49 1","pages":"1189"},"PeriodicalIF":1.3,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47363037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"经济学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-01DOI: 10.1007/s10663-022-09532-1
Piotr Ciżkowicz, Grzegorz Parosa, A. Rzońca
{"title":"Fiscal tensions and risk premium","authors":"Piotr Ciżkowicz, Grzegorz Parosa, A. Rzońca","doi":"10.1007/s10663-022-09532-1","DOIUrl":"https://doi.org/10.1007/s10663-022-09532-1","url":null,"abstract":"","PeriodicalId":46526,"journal":{"name":"Empirica","volume":"49 1","pages":"833-896"},"PeriodicalIF":1.3,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52382713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"经济学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-24DOI: 10.1007/s10663-022-09543-y
A. Eder, W. Koller, B. Mahlberg
{"title":"Economy 4.0: employment effects by occupation, industry, and gender","authors":"A. Eder, W. Koller, B. Mahlberg","doi":"10.1007/s10663-022-09543-y","DOIUrl":"https://doi.org/10.1007/s10663-022-09543-y","url":null,"abstract":"","PeriodicalId":46526,"journal":{"name":"Empirica","volume":"49 1","pages":"1063 - 1088"},"PeriodicalIF":1.3,"publicationDate":"2022-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43238484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"经济学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-15DOI: 10.1007/s10663-022-09544-x
T. Baležentis, Vaida Šapolaitė
{"title":"Productivity surplus and its distribution in Lithuanian agriculture","authors":"T. Baležentis, Vaida Šapolaitė","doi":"10.1007/s10663-022-09544-x","DOIUrl":"https://doi.org/10.1007/s10663-022-09544-x","url":null,"abstract":"","PeriodicalId":46526,"journal":{"name":"Empirica","volume":"49 1","pages":"721 - 740"},"PeriodicalIF":1.3,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45943954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"经济学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-09DOI: 10.1007/s10663-022-09541-0
J. Hou, S. Schuler
{"title":"The nonlinear effect of financial literacy on wealth: evidence from Germany","authors":"J. Hou, S. Schuler","doi":"10.1007/s10663-022-09541-0","DOIUrl":"https://doi.org/10.1007/s10663-022-09541-0","url":null,"abstract":"","PeriodicalId":46526,"journal":{"name":"Empirica","volume":"49 1","pages":"627 - 661"},"PeriodicalIF":1.3,"publicationDate":"2022-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45861007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"经济学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-05eCollection Date: 2022-01-01DOI: 10.1155/2022/5249367
Ling Zhu, Lei Jia, Na Liu, Runmiao Wu, Gongchang Guan, Rutai Hui, Yujie Xing, Yong Zhang, Junkui Wang
Background: DNA methylation plays a key role in establishing cell type-specific gene expression profiles and patterns in atherosclerosis. The underlying mechanism remains unclear. Previous studies have shown that DNA methyltransferase 3b (DNMT3b) may play an important role in atherosclerosis. This study aimed to establish the regulatory role of DNMT3b in the development of atherosclerosis.
Methods: We constructed a viral vector carrying Dnmt3b shRNA to transduce ApoE-/- mice. Meanwhile, healthy human peripheral blood Treg cells were treated with inhibitor of DNMT3b (AZA and EGCG) or transduced with DNMT3b shRNA.
Results: It showed that Dnmt3b silencing attenuated atherosclerosis, including decreased lesion size and macrophage content and increased collagen and smooth muscle cells content in ApoE-/- mice. To further investigate the possible mechanisms, combined with previous studies by our group, we showed that Foxp3-TSDR methylation level was significantly reduced Foxp3 expression and peripheral blood Treg levels were significantly increased by Dnmt3b shRNA vector transduction in animals committed to western diet for 12 and 18 weeks. Consistently, inhibition of DNMT3b (AZA and EGCG) decreased the expression levels of DNMT3b, which can increase the expression levels of FOXP3, and increase the levels of TGF-β and IL-10 and decrease the levels of IL-β and IFN-γ. After transduction with DNMT3b shRNA, the effect was more obvious.
Conclusions: DNMT3b accelerated atherosclerosis, and may be associated with FOXP3 hypermethylation status in regulatory T cells.
{"title":"DNA Methyltransferase 3b Accelerates the Process of Atherosclerosis.","authors":"Ling Zhu, Lei Jia, Na Liu, Runmiao Wu, Gongchang Guan, Rutai Hui, Yujie Xing, Yong Zhang, Junkui Wang","doi":"10.1155/2022/5249367","DOIUrl":"10.1155/2022/5249367","url":null,"abstract":"<p><strong>Background: </strong>DNA methylation plays a key role in establishing cell type-specific gene expression profiles and patterns in atherosclerosis. The underlying mechanism remains unclear. Previous studies have shown that DNA methyltransferase 3b (DNMT3b) may play an important role in atherosclerosis. This study aimed to establish the regulatory role of DNMT3b in the development of atherosclerosis.</p><p><strong>Methods: </strong>We constructed a viral vector carrying Dnmt3b shRNA to transduce ApoE<sup>-/-</sup> mice. Meanwhile, healthy human peripheral blood Treg cells were treated with inhibitor of DNMT3b (AZA and EGCG) or transduced with DNMT3b shRNA.</p><p><strong>Results: </strong>It showed that Dnmt3b silencing attenuated atherosclerosis, including decreased lesion size and macrophage content and increased collagen and smooth muscle cells content in ApoE<sup>-/-</sup> mice. To further investigate the possible mechanisms, combined with previous studies by our group, we showed that <i>Foxp3</i>-TSDR methylation level was significantly reduced Foxp3 expression and peripheral blood Treg levels were significantly increased by Dnmt3b shRNA vector transduction in animals committed to western diet for 12 and 18 weeks. Consistently, inhibition of DNMT3b (AZA and EGCG) decreased the expression levels of DNMT3b, which can increase the expression levels of FOXP3, and increase the levels of TGF-<i>β</i> and IL-10 and decrease the levels of IL-<i>β</i> and IFN-<i>γ</i>. After transduction with DNMT3b shRNA, the effect was more obvious.</p><p><strong>Conclusions: </strong>DNMT3b accelerated atherosclerosis, and may be associated with FOXP3 hypermethylation status in regulatory T cells.</p>","PeriodicalId":46526,"journal":{"name":"Empirica","volume":"41 1","pages":"5249367"},"PeriodicalIF":0.0,"publicationDate":"2022-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9005271/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74006879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"经济学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-02DOI: 10.1007/s10663-022-09537-w
Martin Hodula, Ngoc Anh Ngo
This paper examines the interactions between financial development, economic growth and (macro)prudential policy on a sample of 12 euro area countries. Our main takeaway is that active (macro)prudential policy supports the positive finance-growth nexus instead of disrupting it. These benefits are found to be more likely to materialize during tightening of (macro)prudential policy measures and not during easing. This result is conditional on the ability of (macro)prudential policy to curb excess credit growth and mitigate systemic risk, which would otherwise disrupt the market. Moreover, we assert that when analysing the effects of (macro)prudential policy, it is important to account for the direction of (macro)prudential measures, not just for the frequency at which they are implemented.
{"title":"Finance, growth and (macro)prudential policy: European evidence","authors":"Martin Hodula, Ngoc Anh Ngo","doi":"10.1007/s10663-022-09537-w","DOIUrl":"https://doi.org/10.1007/s10663-022-09537-w","url":null,"abstract":"<p>This paper examines the interactions between financial development, economic growth and (macro)prudential policy on a sample of 12 euro area countries. Our main takeaway is that active (macro)prudential policy supports the positive finance-growth nexus instead of disrupting it. These benefits are found to be more likely to materialize during tightening of (macro)prudential policy measures and not during easing. This result is conditional on the ability of (macro)prudential policy to curb excess credit growth and mitigate systemic risk, which would otherwise disrupt the market. Moreover, we assert that when analysing the effects of (macro)prudential policy, it is important to account for the direction of (macro)prudential measures, not just for the frequency at which they are implemented.</p>","PeriodicalId":46526,"journal":{"name":"Empirica","volume":"232 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2022-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138514311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"经济学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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