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Analyzing complex functional brain networks: Fusing statistics and network science to understand the brain*† 分析复杂的脑功能网络:融合统计学和网络科学来理解大脑*†
IF 3.3 Q1 STATISTICS & PROBABILITY Pub Date : 2013-01-01 DOI: 10.1214/13-SS103
Sean L Simpson, F DuBois Bowman, Paul J Laurienti

Complex functional brain network analyses have exploded over the last decade, gaining traction due to their profound clinical implications. The application of network science (an interdisciplinary offshoot of graph theory) has facilitated these analyses and enabled examining the brain as an integrated system that produces complex behaviors. While the field of statistics has been integral in advancing activation analyses and some connectivity analyses in functional neuroimaging research, it has yet to play a commensurate role in complex network analyses. Fusing novel statistical methods with network-based functional neuroimage analysis will engender powerful analytical tools that will aid in our understanding of normal brain function as well as alterations due to various brain disorders. Here we survey widely used statistical and network science tools for analyzing fMRI network data and discuss the challenges faced in filling some of the remaining methodological gaps. When applied and interpreted correctly, the fusion of network scientific and statistical methods has a chance to revolutionize the understanding of brain function.

复杂的脑功能网络分析在过去十年中爆炸式增长,由于其深刻的临床意义而获得关注。网络科学(图论的一个跨学科分支)的应用促进了这些分析,并使研究大脑作为一个产生复杂行为的综合系统成为可能。虽然在功能性神经成像研究中,统计领域在推进激活分析和一些连通性分析方面已经不可或缺,但它在复杂网络分析中尚未发挥相应的作用。将新颖的统计方法与基于网络的功能性神经图像分析相结合,将产生强大的分析工具,这将有助于我们理解正常的大脑功能以及由于各种大脑疾病而引起的变化。在这里,我们调查了用于分析fMRI网络数据的广泛使用的统计和网络科学工具,并讨论了在填补一些剩余的方法空白方面所面临的挑战。当应用和解释正确时,网络科学和统计方法的融合有机会彻底改变对大脑功能的理解。
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引用次数: 122
Prediction in several conventional contexts 几种常规情况下的预测
IF 3.3 Q1 STATISTICS & PROBABILITY Pub Date : 2012-12-01 DOI: 10.1214/12-SS100
B. Clarke, J. Clarke
We review predictive techniques from several traditional branches of statistics. Starting with prediction based on the normal model and on the empirical distribution function, we proceed to techniques for various forms of regression and classification. Then, we turn to time series, longitudinal data, and survival analysis. Our focus throughout is on the mechanics of prediction more than on the properties of predictors.
我们回顾了几个传统统计学分支的预测技术。从基于正态模型和经验分布函数的预测开始,我们继续讨论各种形式的回归和分类技术。然后,我们转向时间序列、纵向数据和生存分析。我们自始至终关注的是预测的机制,而不是预测者的属性。
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引用次数: 3
Statistical inference for dynamical systems: A review 动力系统的统计推断:综述
IF 3.3 Q1 STATISTICS & PROBABILITY Pub Date : 2012-04-27 DOI: 10.1214/15-SS111
K. Mcgoff, S. Mukherjee, N. Pillai
The topic of statistical inference for dynamical systems has been studied widely across several fields. In this survey we focus on methods related to parameter estimation for nonlinear dynamical systems. Our objective is to place results across distinct disciplines in a common setting and highlight opportunities for further research.
动力系统的统计推断已经在多个领域得到了广泛的研究。在这篇综述中,我们着重于非线性动力系统参数估计的相关方法。我们的目标是将不同学科的结果放在一个共同的环境中,并突出进一步研究的机会。
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引用次数: 38
A survey of Bayesian predictive methods for model assessment, selection and comparison 贝叶斯预测方法在模型评估、选择和比较中的应用综述
IF 3.3 Q1 STATISTICS & PROBABILITY Pub Date : 2012-01-01 DOI: 10.1214/12-SS102
Aki Vehtari, Janne Ojanen
To date, several methods exist in the statistical literature for model assessment, which purport themselves specifically as Bayesian predic- tive methods. The decision theoretic assumptions on which these methods are based are not always clearly stated in the original articles, however. The aim of this survey is to provide a unified review of Bayesian predictive model assessment and selection methods, and of methods closely related to them. We review the various assumptions that are made in this context and discuss the connections between different approaches, with an emphasis on how each method approximates the expected utility of using a Bayesian model for the purpose of predicting future data.
迄今为止,统计文献中存在几种用于模型评估的方法,它们声称自己具体为贝叶斯预测方法。然而,这些方法所基于的决策理论假设并不总是在原始文章中明确说明。本文的目的是对贝叶斯预测模型的评估和选择方法以及与之密切相关的方法进行综述。我们回顾了在这种情况下做出的各种假设,并讨论了不同方法之间的联系,重点是每种方法如何近似使用贝叶斯模型来预测未来数据的预期效用。
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引用次数: 318
A review of survival trees 生存树的回顾
IF 3.3 Q1 STATISTICS & PROBABILITY Pub Date : 2011-08-01 DOI: 10.1214/09-SS047
Imad Bou-Hamad, Denis Larocque, H. Ben-Ameur
This paper presents a non–technical account of the developments in tree–based methods for the analysis of survival data with censoring. This review describes the initial developments, which mainly extended the existing basic tree methodologies to censored data as well as to more recent work. We also cover more complex models, more specialized methods, and more specific problems such as multivariate data, the use of time–varying covariates, discrete–scale survival data, and ensemble methods applied to survival trees. A data example is used to illustrate some methods that are implemented in R.
本文提出了一个非技术的发展,以树为基础的方法来分析与审查的生存数据。这篇综述描述了最初的发展,主要是将现有的基本树方法扩展到审查数据以及最近的工作。我们还涵盖了更复杂的模型、更专业的方法和更具体的问题,如多变量数据、时变协变量的使用、离散尺度生存数据和应用于生存树的集成方法。使用一个数据示例来说明在R中实现的一些方法。
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引用次数: 179
Curse of dimensionality and related issues in nonparametric functional regression 非参数泛函回归中的维数诅咒及相关问题
IF 3.3 Q1 STATISTICS & PROBABILITY Pub Date : 2011-01-01 DOI: 10.1214/09-SS049
G. Geenens
Recently, some nonparametric regression ideas have been extended to the case of functional regression. Within that framework, the main concern arises from the infinite dimensional nature of the explanatory objects. Specifically, in the classical multivariate regression context, it is well-known that any nonparametric method is affected by the socalled “curse of dimensionality”, caused by the sparsity of data in highdimensional spaces, resulting in a decrease in fastest achievable rates of convergence of regression function estimators toward their target curve as the dimension of the regressor vector increases. Therefore, it is not surprising to find dramatically bad theoretical properties for the nonparametric functional regression estimators, leading many authors to condemn the methodology. Nevertheless, a closer look at the meaning of the functional data under study and on the conclusions that the statistician would like to draw from it allows to consider the problem from another point-of-view, and to justify the use of slightly modified estimators. In most cases, it can be entirely legitimate to measure the proximity between two elements of the infinite dimensional functional space via a semi-metric, which could prevent those estimators suffering from what we will call the “curse of infinite dimensionality”. AMS 2000 subject classifications: Primary 62G08; secondary 62M40.
近年来,一些非参数回归的思想被推广到函数回归的情况。在这个框架中,主要的关注来自于解释性对象的无限维度性质。具体来说,在经典的多元回归环境中,众所周知,任何非参数方法都受到所谓的“维数诅咒”的影响,这是由高维空间中数据的稀疏性引起的,导致回归函数估计器向目标曲线的最快收敛速度随着回归向量维数的增加而降低。因此,发现非参数泛函回归估计的理论性质非常糟糕并不奇怪,导致许多作者谴责这种方法。然而,仔细观察所研究的功能数据的意义和统计学家想从中得出的结论,可以从另一个角度考虑这个问题,并证明使用稍微修改的估计器是合理的。在大多数情况下,通过半度量来测量无限维函数空间中两个元素之间的接近度是完全合理的,这可以防止那些估计者遭受我们所谓的“无限维诅咒”。AMS 2000学科分类:初级62G08;二次62 m40。
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引用次数: 91
Data confidentiality: A review of methods for statistical disclosure limitation and methods for assessing privacy 数据保密:统计披露方法、限制和隐私评估方法综述
IF 3.3 Q1 STATISTICS & PROBABILITY Pub Date : 2011-01-01 DOI: 10.1214/11-SS074
Gregory J. Matthews, O. Harel
There is an ever increasing demand from researchers for access to useful microdata files. However, there are also growing concerns regarding the privacy of the individuals contained in the microdata. Ideally, microdata could be released in such a way that a balance between usefulness of the data and privacy is struck. This paper presents a review of proposed methods of statistical disclosure control and techniques for assessing the privacy of such methods under different definitions of disclosure. AMS 2000 subject classifications: Primary 62A01.
研究人员对获取有用的微数据文件的需求不断增加。然而,人们对微数据中个人隐私的担忧也日益增加。理想情况下,微数据可以以这样一种方式发布,即在数据的有用性和隐私之间取得平衡。本文综述了统计披露控制的建议方法,以及在不同披露定义下评估这些方法的隐私性的技术。AMS 2000学科分类:初级62A01。
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引用次数: 88
Primal and dual model representations in kernel-based learning 基于核的学习中的原始和对偶模型表示
IF 3.3 Q1 STATISTICS & PROBABILITY Pub Date : 2010-01-01 DOI: 10.1214/09-SS052
J. Suykens, C. Alzate, K. Pelckmans
Abstract: This paper discusses the role of primal and (Lagrange) dual model representations in problems of supervised and unsupervised learning. The specification of the estimation problem is conceived at the primal level as a constrained optimization problem. The constraints relate to the model which is expressed in terms of the feature map. From the conditions for optimality one jointly finds the optimal model representation and the model estimate. At the dual level the model is expressed in terms of a positive definite kernel function, which is characteristic for a support vector machine methodology. It is discussed how least squares support vector machines are playing a central role as core models across problems of regression, classification, principal component analysis, spectral clustering, canonical correlation analysis, dimensionality reduction and data visualization.
摘要:本文讨论了原始和(拉格朗日)对偶模型表示在监督学习和无监督学习问题中的作用。估计问题的说明在原始层次上被认为是一个约束优化问题。约束与模型相关,模型用特征映射表示。从最优性条件出发,共同求出最优模型表示和模型估计。在对偶层次上,模型用正定核函数表示,这是支持向量机方法的特点。讨论了最小二乘支持向量机作为核心模型如何在回归、分类、主成分分析、谱聚类、典型相关分析、降维和数据可视化等问题中发挥核心作用。
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引用次数: 31
Finite mixture models and model-based clustering 有限混合模型和基于模型的聚类
IF 3.3 Q1 STATISTICS & PROBABILITY Pub Date : 2010-01-01 DOI: 10.1214/09-SS053
Volodymyr Melnykov, R. Maitra
Finite mixture models have a long history in statistics, hav- ing been used to model pupulation heterogeneity, generalize distributional assumptions, and lately, for providing a convenient yet formal framework for clustering and classication. This paper provides a detailed review into mixture models and model-based clustering. Recent trends in the area, as well as open problems are also discussed.
有限混合模型在统计学中有着悠久的历史,已经被用来模拟人口异质性,推广分布假设,最近,为聚类和分类提供了一个方便而正式的框架。本文详细介绍了混合模型和基于模型的聚类。本文还讨论了该领域的最新发展趋势以及有待解决的问题。
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引用次数: 262
The ARMA alphabet soup: A tour of ARMA model variants ARMA字母汤:ARMA模型变体之旅
IF 3.3 Q1 STATISTICS & PROBABILITY Pub Date : 2010-01-01 DOI: 10.1214/09-SS060
S. Holan, R. Lund, Ginger M. Davis
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引用次数: 44
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