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Plate Breakage Following Internal Fixation of Long Bone Diaphyseal Fractures: A 150-Case Analysis. 长骨骨干骨折内固定后钢板断裂150例分析。
IF 1.2 Q3 ORTHOPEDICS Pub Date : 2025-01-01 DOI: 10.22038/ABJS.2024.76775.3550
Yan-Zi Liu, Wei Zhu, Tian Xue-Dong

Objectives: This study analyzed cases of plate breakage following internal fixation of long bone diaphyseal fractures to identify contributing factors and inform clinical practice.

Methods: A retrospective analysis of 150 plate breakage cases after diaphyseal fracture fixation was conducted using data from the "DXY" forum in November 2023. Patient demographics, fracture characteristics, plate specifications, surgical techniques, and outcomes were evaluated.

Results: Plate breakages occurred most frequently in the femur (67.3%), predominantly in wedge or multifragmentary fractures (60.7%). Locking plates were used in 64.7% of cases. Despite high rates of anatomical reduction (87.9% in complex fractures), plate failures occurred at an average of 11.3 months post-operation. High screw density (0.83-0.89 screws used/total holes) was observed across fracture types. In femoral fractures, the fracture zone length to working plate length ratio was notably high (0.91), indicating a relatively short working length.

Conclusion: Findings suggest that prioritizing anatomical reduction and rigid fixation may contribute to plate breakage, potentially due to impaired biological healing. Adherence to contemporary AO principles, emphasizing relative stability and biological fixation techniques, may be crucial in preventing these complications. The study highlights the need for a balanced approach between mechanical stability and biological considerations in fracture management.

目的:分析长骨骨干骨折内固定后钢板断裂的病例,找出导致骨折的因素,为临床提供参考。方法:回顾性分析2015年11月《DXY》杂志刊载的150例骨干骨折固定后钢板断裂病例。评估患者人口统计学、骨折特征、钢板规格、手术技术和结果。结果:钢板骨折多发于股骨(67.3%),以楔形或多块骨折为主(60.7%)。64.7%的病例使用锁定钢板。尽管解剖复位率很高(复杂骨折87.9%),但术后平均11.3个月发生钢板失效。不同骨折类型均观察到较高的螺钉密度(0.83-0.89颗螺钉/总孔数)。在股骨骨折中,骨折区长度与工作钢板长度之比明显较高(0.91),说明工作长度相对较短。结论:研究结果表明,优先考虑解剖复位和刚性固定可能导致钢板断裂,这可能是由于生物愈合受损。坚持当代AO原则,强调相对稳定性和生物固定技术,可能是预防这些并发症的关键。该研究强调了在骨折管理中需要平衡机械稳定性和生物因素。
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引用次数: 0
Lumbosacral Vertebral Angles can Predict Lumbosacral Transitional Vertebrae on Routine Sagittal MRI. 腰骶椎角度可以预测常规矢状位MRI的腰骶过渡椎。
IF 1.2 Q3 ORTHOPEDICS Pub Date : 2025-01-01 DOI: 10.22038/ABJS.2025.83244.3790
Farrokh Seilanian Toosi, Bahare Mahdianfar, Ahmadreza Zarifian, Ehsan Keykhosravi, Amir Mahmoud Ahmadzadeh, Maryam Ghandhari, Farzaneh Khoroushi, Maryam Emadzadeh, Hormoz Abedi, Behzad Aminzadeh

Objectives: We aimed to measure lumbosacral vertebral angles in routine lumbar sagittal MRIs and assess their association with lumbosacral transitional vertebrae (LSTV).

Methods: We recruited 220 patients referring to our hospital for routine lumbar MRI during 2020-2021. All the participants were subject to routine sagittal lumbar MRI, whole spine localizer scan, and coronal MRI to numerate lumbar vertebrae. Five vertebral angles (A, B, C, D, and delta) and dehydration in L4-L5 and L5-S1 discs were assessed in sagittal MRI scans. Data were analyzed using SPSS 26.

Results: Out of 220 participants (mean age: 44.29 ± 14.14 years), 36 (16.36%) were diagnosed with LSTV. Among those diagnosed with LSTV, L5-S1 dehydration was less frequently observed compared to other participants (P < 0.001). Multivariate regression showed that dehydrated L4-L5 disc, non-dehydrated L5-S1 disc, increased A-angle, and decreased D-angle can independently predict LSTV. The median A-angle was significantly larger in LSTV patients than in non-LSTV participants (P = 0.038), while the medians of C-angle, D-angle, and delta-angle were significantly smaller in the LSTV group (P < 0.05). A C-angle ≤ 35.5˚ could diagnose LSTV with sensitivity and specificity of 72.2% and 57.6%, respectively. A delta angle ≤ 8.5˚ could diagnose type 2 LSTV with 92.3% sensitivity and 87.9% specificity.

Conclusion: Measuring lumbosacral vertebral angles, especially delta-angle, in routine sagittal MRI can potentially alert physicians of a likely LSTV diagnosis.

目的:我们的目的是在常规腰椎矢状面mri中测量腰骶椎体角,并评估其与腰骶移行椎体(LSTV)的关系。方法:在2020-2021年期间,我们招募了220名患者来我院进行常规腰椎MRI检查。所有参与者均接受常规腰椎矢状位MRI,全脊柱定位扫描和冠状位MRI以计算腰椎。在矢状面MRI扫描中评估L4-L5和L5-S1椎间盘的5个椎体角(A、B、C、D和delta)和脱水情况。数据采用SPSS 26进行分析。结果:220名参与者(平均年龄:44.29±14.14岁)中,36名(16.36%)被诊断为LSTV。在诊断为LSTV的患者中,与其他参与者相比,L5-S1脱水的发生率较低(P < 0.001)。多元回归结果显示,L4-L5椎间盘脱水、L5-S1椎间盘未脱水、a角增大、d角减小均能独立预测LSTV。LSTV组患者a角中位数明显大于非LSTV组(P = 0.038),而LSTV组c角、d角、delta角中位数明显小于非LSTV组(P < 0.05)。c角≤35.5˚诊断LSTV的敏感性和特异性分别为72.2%和57.6%。δ角≤8.5˚诊断2型LSTV的敏感性为92.3%,特异性为87.9%。结论:在常规矢状位MRI中测量腰骶椎角,特别是三角角,可以潜在地提醒医生可能的LSTV诊断。
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引用次数: 0
Correlation between Adult Height and Metacarpal Length Using Advanced Imaging Modalities. 成人身高与掌骨长度的相关性研究
IF 1.2 Q3 ORTHOPEDICS Pub Date : 2025-01-01 DOI: 10.22038/ABJS.2024.80233.3672
Pedro K Beredjiklian, Gregory G Gallant, Rick Tosti, Moody Kwok, Jeremiah A Adams, Daniel Fletcher

Objectives: The primary objective of this study was to evaluate the correlation between height and metacarpal length in normal adults using computed tomographic (CT) scans. A secondary aim was to determine if differences exist between various finger metacarpals. We hypothesized a direct correlation between height and metacarpal length, with consistent proportions across different finger metacarpals.

Methods: This radiographic study analyzed 40 CT scans of skeletally mature adult patients. Measurements of the metacarpal lengths were taken using the Sectra IDS7 diagnostic imaging platform. Patient demographics, including age, sex, height, weight, and BMI, were collected. Differences between genders and among metacarpals were assessed using independent sample t-tests, while Pearson correlation coefficients determined the relationship between height and metacarpal length. Statistical significance was defined at P<0.05.

Results: The study population consisted of 28 men and 12 women, with an average age of 42.6 years. The mean heights and weights were 175.3 cm and 87.4 kg, respectively. The average lengths of the metacarpals were: index, 67.7 mm; long, 66.1 mm; ring, 58 mm; small, 52.3 mm. Pearson correlation coefficients between height and metacarpal lengths averaged 0.71, indicating a statistically significant positive correlation across all metacarpals. The index metacarpal most closely correlated with patient height.

Conclusion: Our findings confirm a significant positive correlation between height and metacarpal length, supporting the hypothesis of a direct relationship. These results suggest that height can be a useful predictor for metacarpal length, potentially aiding in the selection of orthopedic implants and surgical planning for metacarpal fractures. CT scans provide precise measurements, underscoring their value in assessing bony anatomy. Future studies with larger and more diverse populations are needed to validate these findings and explore potential sex-based differences in metacarpal dimensions.

目的:本研究的主要目的是利用计算机断层扫描(CT)评估正常成人身高和掌骨长度之间的相关性。第二个目的是确定不同手指掌骨之间是否存在差异。我们假设身高和掌骨长度之间有直接关系,不同手指掌骨的比例一致。方法:本影像学研究分析了40例骨骼成熟成人患者的CT扫描。使用Sectra IDS7诊断成像平台测量掌骨长度。收集患者的人口统计资料,包括年龄、性别、身高、体重和BMI。使用独立样本t检验评估性别之间和掌骨之间的差异,Pearson相关系数确定身高和掌骨长度之间的关系。结果中定义了统计学意义:研究人群包括28名男性和12名女性,平均年龄为42.6岁。平均身高175.3 cm,体重87.4 kg。掌骨平均长度为:指数,67.7 mm;长,66.1 mm;环,58毫米;小,52.3毫米。身高与掌骨长度之间的Pearson相关系数平均为0.71,表明所有掌骨之间具有统计学意义的正相关。掌骨指数与患者身高的关系最为密切。结论:我们的研究结果证实了身高和掌骨长度之间的显著正相关,支持了直接关系的假设。这些结果表明,身高可以作为掌骨长度的一个有用的预测指标,可能有助于选择骨科植入物和掌骨骨折的手术计划。CT扫描提供了精确的测量,强调了其在评估骨骼解剖中的价值。未来需要对更大、更多样化的人群进行研究,以验证这些发现,并探索掌骨尺寸的潜在性别差异。
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引用次数: 0
Occupational and Non-Occupational Risk Factors for Neck Pain in Dentists: A Systematic Review and Meta-Analysis. 牙医颈部疼痛的职业和非职业危险因素:系统回顾和荟萃分析。
IF 1.2 Q3 ORTHOPEDICS Pub Date : 2025-01-01 DOI: 10.22038/ABJS.2024.78260.3604
Ehsan Rafeemanesh, Farzad Omidi-Kashani, Alireza Chamani, Sarvenaz Allahdad

Objectives: Musculoskeletal disorders (MSDs), notably neck pain, are important occupational health issues in the field of dentistry. The aim of the present study was to systematically review the literature for significant ris k factors for neck pain in dentists.

Methods: PubMed and Scopus were searched with the following search strategy: (neck AND dentist AND pain). Data regarding the prevalence of each estimated risk factor were extracted, and studies with enough quantitative data were further analyzed using meta-analysis. The last search was done on October 2023. The calculated effect size for each study was based on the odds ratio (OR). All statistical analyses were performed using Comprehensive Meta-Analysis Software (version 2).

Results: In total, 42 cross-sectional studies met our inclusion criteria for the current systematic review, with 34 of them selected for inclusion in the meta-analysis. There was a significant relationship between dentists' neck pain and age (over 40 years old), female gender, working experience (more than 10 years), and height (exceeding 180 cm). Dentists with physical activity (OR=0.2, 95% CI: 0.04-0.9) and stretching (OR=0.6, 95% CI: 0.4-1.0) had a significantly lower risk of neck pain compared to dentists without physical activity and stretching during the week after the treatment session. The use of vibrating tools increased the risk of neck pain among dentists (OR=1.6, 95% CI: 1.1-2.4). The number of compromised and harmful postures was significantly associated with an increased risk of neck pain across studies; however, the data were not enough for running a meta-analysis on this subject.

Conclusion: Poor cervical posture, older age, prolonged working experience, and a larger number of treated patients were identified as significant risk factors associated with neck pain. Ergonomic improvements, regular physical activity, rest breaks, stretching, and indirect vision play a crucial role in mitigating the risk of neck pain.

目的:肌肉骨骼疾病(MSDs),特别是颈部疼痛,是牙科领域重要的职业健康问题。本研究的目的是系统地回顾文献中牙医颈部疼痛的重要危险因素。方法:检索PubMed和Scopus,检索策略:(neck and dental and pain)。提取各估计危险因素的患病率数据,并对有足够定量数据的研究进行meta分析。最后一次搜索是在2023年10月。每项研究的计算效应大小是基于优势比(OR)。所有统计分析均使用综合元分析软件(version 2)进行。结果:总共有42项横断面研究符合当前系统评价的纳入标准,其中34项被纳入meta分析。牙医颈痛与年龄(40岁以上)、女性、工作年限(10年以上)、身高(180 cm以上)有显著相关。在治疗后的一周内,进行体力活动(OR=0.2, 95% CI: 0.04-0.9)和拉伸(OR=0.6, 95% CI: 0.4-1.0)的牙医与没有进行体力活动和拉伸的牙医相比,颈部疼痛的风险显著降低。使用振动工具增加了牙医颈部疼痛的风险(OR=1.6, 95% CI: 1.1-2.4)。在所有研究中,受损和有害姿势的数量与颈部疼痛风险增加显著相关;然而,这些数据不足以对这一主题进行荟萃分析。结论:颈位不良、年龄大、工作经验长、就诊患者多是颈痛发生的重要危险因素。人体工程学的改进、有规律的身体活动、休息休息、伸展运动和间接视觉在减轻颈部疼痛的风险方面起着至关重要的作用。
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引用次数: 0
How to Perform an Accurate and Safe Medial Open Wedge High Tibial Osteotomy; A Technical Note. 如何进行准确、安全的胫骨内侧开楔高位截骨术技术说明。
IF 1.2 Q3 ORTHOPEDICS Pub Date : 2025-01-01 DOI: 10.22038/ABJS.2025.81222.3703
Arash Sherafat Vaziri, Hossein Ahmadzadeh, Nima Hosseinzadeh

Medial open-wedge high tibial osteotomy (MOWHTO) is increasingly recognized as the preferred treatment option for active patients with varus malalignment and medial compartment osteoarthritis of the knee. This procedure aims to delay the degenerative process while alleviating pain and dysfunction. In this technical note, we aim to describe the tips and tricks for performing a safe MOWHTO, drawing on recent literature.

内侧开楔高位胫骨截骨术(MOWHTO)越来越被认为是膝关节内翻错位和内侧骨关节炎患者的首选治疗方案。该手术旨在延缓退行性过程,同时减轻疼痛和功能障碍。在这个技术说明中,我们的目的是描述执行安全的MOWHTO的提示和技巧,借鉴最近的文献。
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引用次数: 0
Outcomes of Patients with Bennett Fracture Treated with Three Different Surgical Techniques: A Systematic Review. 采用三种不同手术技术治疗贝内特骨折患者的疗效:系统回顾
IF 1.2 Q3 ORTHOPEDICS Pub Date : 2025-01-01 DOI: 10.22038/ABJS.2024.81116.3702
Eduardo Velásquez-Girón, Edna Rocio Buitrago-Quiñonez, Jorge Hernández-Guevara, Álvaro Antonio Kafury

Objectives: Bennett's fracture, the most common intra-articular fracture occurring at the base of the thumb, accounts for less than 1% of all hand fractures. It typically results from specific traumatic mechanisms, deforming forces, and ligamentous injuries. To compare the functional outcomes and sequelae in patients with Bennett's fracture treated surgically using: Open reduction and internal screw fixation, closed reduction and percutaneous fixation, arthroscopy-assisted reduction and screw fixation.

Methods: A systematic literature review was conducted to identify studies on Bennett's fracture dislocations in patients over 18 years of age without additional injuries. Searches were performed in PubMed, Scopus, Cochrane Central, Web of Science, Scielo, Lilacs, Oneme, and Epistemonikos databases, with language restrictions in English, French, Spanish, Portuguese, Italian, and German, and no date restrictions. Primary outcome variables included measures of functionality and secondary outcomes such as pain, stiffness, and osteoarthritis.

Results: A total of 18 studies met the selection criteria, with most being retrospective (94.45%). Pain measures were reported in 77.78% of the studies, predominantly using the VAS (min=0 and max=2). All techniques seemed to achieve similar functional outcomes. The main difference was the pain registered at follow-up, mainly by patients treated with open reduction. Osteoarthritis appeared as a common consequence of these fractures, regardless of the treatment type -excluding arthroscopy-assisted reduction as there was not enough data.

Conclusion: The three techniques had similar functional outcomes. Closed reduction and percutaneous fixation appear to result in less pain; however, both closed reduction with percutaneous fixation and open reduction with internal screw fixation have similar rates of osteoarthritis at follow-up. Unfortunately, there is insufficient data to evaluate arthroscopy-assisted reduction with screw fixation, suggesting the need for rigorous follow-up in patients undergoing this surgical intervention.

目的:本内特骨折是发生在拇指基部的最常见的关节内骨折,占所有手部骨折的不到1%。它通常由特定的创伤机制、变形力和韧带损伤引起。比较切开复位内钉固定、闭合复位经皮固定、关节镜辅助复位螺钉固定治疗Bennett骨折患者的功能结局和后遗症。方法:对18岁以上无附加损伤患者的Bennett骨折脱位进行系统的文献综述。检索在PubMed、Scopus、Cochrane Central、Web of Science、Scielo、Lilacs、Oneme和Epistemonikos数据库中进行,语言限制为英语、法语、西班牙语、葡萄牙语、意大利语和德语,没有日期限制。主要结果变量包括功能测量和次要结果,如疼痛、僵硬和骨关节炎。结果:共有18项研究符合入选标准,其中以回顾性研究居多(94.45%)。77.78%的研究报告了疼痛测量,主要使用VAS (min=0, max=2)。所有的技术似乎都达到了类似的功能结果。主要的区别是随访时记录的疼痛,主要是接受切开复位治疗的患者。骨关节炎是这些骨折的常见后果,无论治疗方式如何-不包括关节镜辅助复位,因为没有足够的数据。结论:三种方法的功能效果相似。闭合复位和经皮固定似乎能减轻疼痛;然而,随访时,经皮闭合复位和切开复位内螺钉固定的骨关节炎发生率相似。不幸的是,没有足够的数据来评估关节镜辅助复位螺钉固定,这表明需要对接受这种手术干预的患者进行严格的随访。
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引用次数: 0
Applications, Implications, and Drawbacks of Artificial Intelligence in Medical Publications. 人工智能在医学出版物中的应用、影响和弊端。
IF 1.2 Q3 ORTHOPEDICS Pub Date : 2025-01-01 DOI: 10.22038/ABJS.2024.82343.3751
Kylen Bruey, Amir R Kachooei
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引用次数: 0
AI-Based Hospital Design Process through Neuro-Symbolic Strategies. 基于神经符号策略的人工智能医院设计过程
IF 1.8 Q3 ORTHOPEDICS Pub Date : 2025-01-01 DOI: 10.22038/ABJS.2024.83867.3815
Ameneh Sadat Fattahi Maassoum, Hero Farkisch, Mohammad Taji

Objectives: Hospitals represent one of the most complex subjects in architectural design. Over time, many hospitals undergo changes in their initial spatial layouts to accommodate evolving needs. This process often presents various challenges and problems, and the absence of an optimal design process for hospitals is a primary contributor to these issues. Artificial intelligence (AI), with its advanced capabilities, can offer highly accurate and rapid solutions. This research aims to present an integrated approach that combines architecture and AI for AI-based hospital design through neuro-symbolic strategies.

Methods: This research employs a theoretical-applied framework, and utilizes a descriptive-analytical method to investigate the role of artificial intelligence in the design process, particularly within hospitals. The data collection methods include a literature review and an examination of texts and studies related to architectural design and AI. Furthermore, by analyzing the data through content analysis, integrated neuro-symbolic strategies were introduced as a comprehensive approach to AI. The final model of the hospital design process, based on this approach, was subsequently presented.

Results: Unified and hybrid techniques are two methods for integrating symbolic and sub-symbolic algorithms within the integrated neuro-symbolic approach. This innovative methodology leverages the strengths of both categories of algorithms while mitigating their respective weaknesses. Among the six methods presented in this paper, the hybrid strategy-method number three (neuro-symbolic) - emerges as the most effective means of achieving an integrated process that merges AI and architecture in hospital design.

Conclusion: In this process, the designer's interventions are minimized, allowing AI to produce the most optimal architectural design for a hospital by leveraging its capabilities.

目的:医院是建筑设计中最复杂的主题之一。随着时间的推移,许多医院的初始空间布局发生了变化,以适应不断变化的需求。这一过程通常会带来各种挑战和问题,而医院缺乏最佳设计过程是造成这些问题的主要原因。人工智能(AI)凭借其先进的能力,可以提供高度准确和快速的解决方案。本研究旨在通过神经符号策略,提出一种结合建筑和人工智能的综合方法,用于基于人工智能的医院设计。方法:本研究采用理论-应用框架,并利用描述-分析方法来研究人工智能在设计过程中的作用,特别是在医院内。数据收集方法包括文献综述和与建筑设计和人工智能相关的文本和研究的检查。此外,通过内容分析对数据进行分析,引入了综合神经符号策略作为人工智能的综合方法。随后提出了基于这种方法的医院设计过程的最终模型。结果:统一技术和混合技术是集成神经符号方法中集成符号和子符号算法的两种方法。这种创新的方法利用了两类算法的优势,同时减轻了它们各自的弱点。在本文提出的六种方法中,混合策略-方法三(神经符号)-成为实现医院设计中合并人工智能和建筑的集成过程的最有效手段。结论:在这个过程中,设计师的干预被最小化,允许AI利用其能力为医院产生最优的建筑设计。
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引用次数: 0
Comparison of Temporary External Fixation and Open Reduction with Internal Fixation for the Management of Pilon Fractures: A Short-Term Outcome Prospective Clinical Trial. 临时外固定和切开复位内固定治疗皮隆骨折的比较:一项短期结果的前瞻性临床试验。
IF 1.2 Q3 ORTHOPEDICS Pub Date : 2025-01-01 DOI: 10.22038/ABJS.2024.82445.3755
Mohamed Salama Hamdy, Ahmed O Sabry, Youhanna Alqess Gawrgios, Sherif Nabeel Amin, Ehab Salah Gado, Mohamed A Ghanem

Objectives: Pilon fractures are among the difficult injuries to treat in orthopedic surgery. We aim to evaluate the feasibility, advantages, and disadvantages of temporary external fixation for pilon fractures and compare its outcomes with cases managed with internal fixation and primary open reduction.

Methods: In a prospective trial, 30 patients were divided into two cohorts: a two-stage cohort with external fixation and secondary ORIF (15 patients) and a one-stage primary ORIF cohort (15 patients). We compared the two cohorts' rates of infection (deep or superficial infection), non-union, malunion, length of hospital stay, patient satisfaction with the American Orthopaedic Foot and Ankle Society (AOFAS) score, and pain level.

Results: All assessed variables showed no significant variations between the two cohorts, except for hospital stay duration, which was substantially more prolonged in the two-stage cohort.

Conclusion: This study demonstrates that both temporary external fixation with secondary ORIF and primary ORIF are viable options for managing pilon fractures. While there were no significant differences in complications between the two treatment modalities, the two-stage approach was associated with a longer hospital stay. These findings suggest that primary ORIF may be preferable when aiming to reduce the duration of hospitalization without compromising clinical outcomes.

目的:皮隆骨折是骨科手术中较难治疗的损伤之一。我们的目的是评估临时外固定治疗头枕骨折的可行性、优点和缺点,并将其与内固定和首次切开复位治疗的病例的结果进行比较。方法:在一项前瞻性试验中,30例患者被分为两个队列:两期外固定和继发性ORIF队列(15例)和一期原发性ORIF队列(15例)。我们比较了两个队列的感染率(深度或浅表感染)、不愈合、不愈合、住院时间、患者对美国骨科足踝协会(AOFAS)评分的满意度和疼痛水平。结果:除了住院时间外,所有评估的变量在两个队列之间没有显着差异,住院时间在两阶段队列中明显更长。结论:本研究表明临时外固定联合二次ORIF和一次ORIF都是治疗皮隆骨折的可行选择。虽然两种治疗方式之间的并发症没有显著差异,但两阶段方法与较长的住院时间相关。这些发现表明,在不影响临床结果的情况下,减少住院时间,首选ORIF。
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引用次数: 0
Complications Rate and Hip Function After Revision of Infected Hip Arthroplasty with Bone Defects using Bone Allografts: A Systematic Review and Meta-Analysis. 使用同种异体骨移植翻修感染性骨缺损髋关节置换术后的并发症发生率和髋关节功能:一项系统回顾和荟萃分析
IF 1.8 Q3 ORTHOPEDICS Pub Date : 2025-01-01 DOI: 10.22038/ABJS.2025.90232.4092
Mahdieh Samei, Sm Javad Mortazavi, Mahdieh Sahebi, Mahla Daliri, Mohsen Dehghani, Reza Hossein Zadeh, Mohammad H Ebrahimzadeh, Omid Shahpari

Objectives: We performed a systematic review and meta-analysis to evaluate complication rates and hip function following the revision of infected hip arthroplasty with bone defects using bone allografts.

Methods: A comprehensive search of the PubMed, Web of Science, Embase, and Cochrane Library databases was conducted up to January 2024 to identify pre-post clinical trials. The primary outcomes assessed were the risk of reinfection, a critical concern for surgeons, and hip functional scores. The methodological quality of the included studies was also evaluated. A weighted mean difference (WMD) with a 95% confidence interval (CI) was used as the pooled estimate for clinical outcomes through random-effects meta-analysis, accounting for heterogeneity across studies.

Results: Of the 2,189 records retrieved, 12 pre-post clinical trials (with fair to good quality) were included in the meta-analysis, involving a total of 342 participants. The pooled mean difference in Harris Hip Score (HHS) was 36.86 (95% CI: 29.58 to 44.13) post-surgery. In a subgroup analysis of studies employing structural grafts, the HHS increased by 36.99 (95% CI: 29.56 to 44.42). The overall reinfection rate was 6%. Subgroup analysis revealed that in studies utilizing morselized and structural allografts, the reinfection rates were 6% and 3%, respectively. The overall mean rate of aseptic loosening was 5%. Subgroup analysis showed that in studies using morselized grafts, the rate of aseptic loosening was 4%. The incidence of dislocation was 2% in the morselized group and 5% in the structural group.

Conclusion: Revision of infected hip arthroplasty with bone defects using bone allografts may improve hip function. Interestingly, morselized allografts are often associated with higher rates of reinfection. Additionally, our findings suggest that structural allografts are associated with increased dislocation rates compared to morselized allografts. This difference may be attributed to the larger and more complex defects that necessitated the use of structural allografts rather than morselized grafts.

目的:我们进行了一项系统回顾和荟萃分析,以评估使用同种异体骨移植物翻修感染性骨缺损髋关节置换术后的并发症发生率和髋关节功能。方法:对PubMed、Web of Science、Embase和Cochrane图书馆数据库进行全面检索,直至2024年1月,以确定临床前-后试验。评估的主要结果是再感染的风险,这是外科医生最关心的问题,以及髋关节功能评分。对纳入研究的方法学质量也进行了评价。通过随机效应荟萃分析,采用加权平均差(WMD)和95%置信区间(CI)作为临床结果的汇总估计,考虑了研究间的异质性。结果:在检索到的2189份记录中,12项临床前后试验(质量一般或较好)被纳入meta分析,共涉及342名参与者。术后Harris髋关节评分(HHS)的总平均差值为36.86 (95% CI: 29.58 ~ 44.13)。在采用结构移植物的亚组分析中,HHS增加了36.99 (95% CI: 29.56 ~ 44.42)。总再感染率为6%。亚组分析显示,在使用块状和结构同种异体移植物的研究中,再感染率分别为6%和3%。总体平均无菌性松动率为5%。亚组分析显示,在使用块状移植物的研究中,无菌性松动率为4%。脱位发生率在摩尔化组为2%,在结构组为5%。结论:采用同种异体骨移植对感染性骨缺损髋关节置换术进行翻修可改善髋关节功能。有趣的是,碎片化的同种异体移植物通常与较高的再感染率相关。此外,我们的研究结果表明,与碎片化异体移植物相比,结构性异体移植物与脱位率增加有关。这种差异可能是由于更大和更复杂的缺陷,需要使用结构性同种异体移植物而不是块状移植物。
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Archives of Bone and Joint Surgery-ABJS
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