Pub Date : 2026-01-28DOI: 10.1186/s12962-026-00722-3
Do Dinh Tung, Ta Van Binh, Nguyen Thanh Lam, Nguyen Duc Long, Nguyen Phuong Linh, Tran Ngoc Tuan, Nguyen Thanh Xuan
{"title":"Complicated foot ulcers and high treatment costs in rural type 2 diabetic patients in vietnam: impact of infections on hospital stays.","authors":"Do Dinh Tung, Ta Van Binh, Nguyen Thanh Lam, Nguyen Duc Long, Nguyen Phuong Linh, Tran Ngoc Tuan, Nguyen Thanh Xuan","doi":"10.1186/s12962-026-00722-3","DOIUrl":"10.1186/s12962-026-00722-3","url":null,"abstract":"","PeriodicalId":47054,"journal":{"name":"Cost Effectiveness and Resource Allocation","volume":"24 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12924343/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146259543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-27DOI: 10.1186/s12962-025-00710-z
Carlos E Rodriguez-Martinez, Jaime Ordonez, Xavier Carbonell-Estrany, John Fullarton, Ian Keary, Barry Rodgers-Gray, Ivonne D'Apremont, Daniel E Noyola, Paulo Andre Ribeiro, Renato T Stein, Nestor Vain, Jean-Eric Tarride, Bosco Paes
Background: The International Risk Scoring Tool (IRST) comprises three risk factors (age relative to the respiratory syncytial virus [RSV] season; household and/or maternal smoking; siblings and/or daycare attendance) and enables the cost-effective targeting of palivizumab to infants born at 32-35 weeks' gestational age (wGA) at greatest risk of related hospitalization (RSVH). This study provides the first evaluation of IRST-guided RSV prophylaxis in Colombia.
Methods: The IRST (with wGA substituted for chronological age as RSV is endemic in Colombia) plus other risk factors were assessed using data from 81 infants born 32-35 wGA with RSVH and 49 gestational- and age-matched controls. A cost-utility model comparing IRST-guided palivizumab versus no prophylaxis from the healthcare provider perspective was then adapted using Colombian costs and data (5% discounting). Infants could experience either RSVH, emergency room medically-attended, RSV infection, or remain uninfected/non-attended, with possible long-term respiratory morbidity up to 18 years of age over a lifetime time horizon.
Results: The most predictive combination of risk factors was the IRST plus mixed breast and formula feeding and maternal education (area under the receiver operating characteristic curve = 0.823). For infants assessed at moderate- and high-risk of RSVH, the cost/quality-adjusted life year (QALY) was COP20,225,126 (USD4,752). Probabilistic sensitivity analyses resulted in a mean of COP22,193,734/QALY (USD5,214/QALY), with a 61.1% probability of palivizumab being cost-effective at a COP28,193,734 (USD6,624; 2022 gross domestic product/capita) willingness-to-pay threshold.
Conclusions: Palivizumab prophylaxis of 32-35 wGA infants at moderate- and high-risk of RSVH, identified using the Colombian-adapted IRST, proved to be cost-effective versus no intervention.
{"title":"Clinical and economic evaluation of risk factor guided respiratory syncytial virus prophylaxis in Colombian preterm infants.","authors":"Carlos E Rodriguez-Martinez, Jaime Ordonez, Xavier Carbonell-Estrany, John Fullarton, Ian Keary, Barry Rodgers-Gray, Ivonne D'Apremont, Daniel E Noyola, Paulo Andre Ribeiro, Renato T Stein, Nestor Vain, Jean-Eric Tarride, Bosco Paes","doi":"10.1186/s12962-025-00710-z","DOIUrl":"10.1186/s12962-025-00710-z","url":null,"abstract":"<p><strong>Background: </strong>The International Risk Scoring Tool (IRST) comprises three risk factors (age relative to the respiratory syncytial virus [RSV] season; household and/or maternal smoking; siblings and/or daycare attendance) and enables the cost-effective targeting of palivizumab to infants born at 32-35 weeks' gestational age (wGA) at greatest risk of related hospitalization (RSVH). This study provides the first evaluation of IRST-guided RSV prophylaxis in Colombia.</p><p><strong>Methods: </strong>The IRST (with wGA substituted for chronological age as RSV is endemic in Colombia) plus other risk factors were assessed using data from 81 infants born 32-35 wGA with RSVH and 49 gestational- and age-matched controls. A cost-utility model comparing IRST-guided palivizumab versus no prophylaxis from the healthcare provider perspective was then adapted using Colombian costs and data (5% discounting). Infants could experience either RSVH, emergency room medically-attended, RSV infection, or remain uninfected/non-attended, with possible long-term respiratory morbidity up to 18 years of age over a lifetime time horizon.</p><p><strong>Results: </strong>The most predictive combination of risk factors was the IRST plus mixed breast and formula feeding and maternal education (area under the receiver operating characteristic curve = 0.823). For infants assessed at moderate- and high-risk of RSVH, the cost/quality-adjusted life year (QALY) was COP20,225,126 (USD4,752). Probabilistic sensitivity analyses resulted in a mean of COP22,193,734/QALY (USD5,214/QALY), with a 61.1% probability of palivizumab being cost-effective at a COP28,193,734 (USD6,624; 2022 gross domestic product/capita) willingness-to-pay threshold.</p><p><strong>Conclusions: </strong>Palivizumab prophylaxis of 32-35 wGA infants at moderate- and high-risk of RSVH, identified using the Colombian-adapted IRST, proved to be cost-effective versus no intervention.</p>","PeriodicalId":47054,"journal":{"name":"Cost Effectiveness and Resource Allocation","volume":" ","pages":"35"},"PeriodicalIF":2.5,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12918000/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146067631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-24DOI: 10.1186/s12962-025-00706-9
Paula Ortega-Perals, Salvador Cruz Rambaud, Javier Sánchez García
{"title":"Does healthcare expenditure matter equally for all mental disorders? An international approach employing dynamic panel data methods.","authors":"Paula Ortega-Perals, Salvador Cruz Rambaud, Javier Sánchez García","doi":"10.1186/s12962-025-00706-9","DOIUrl":"10.1186/s12962-025-00706-9","url":null,"abstract":"","PeriodicalId":47054,"journal":{"name":"Cost Effectiveness and Resource Allocation","volume":" ","pages":"33"},"PeriodicalIF":2.5,"publicationDate":"2026-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12911020/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146044092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-24DOI: 10.1186/s12962-025-00701-0
Manuel Enrique Machado-Duque, Andrés Gaviria-Mendoza, Luis F Valladales-Restrepo, Diego Mauricio Gómez, Alejandro Mesa-Urdinola, Andrea Constanza Rubio, Juan Manuel Reyes, Natalia Castaño Gamboa, Jorge Enrique Machado-Alba
{"title":"Use of resources and cost in the management of gastrointestinal hemorrhage caused by oral anticoagulants: a retrospective cohort analysis.","authors":"Manuel Enrique Machado-Duque, Andrés Gaviria-Mendoza, Luis F Valladales-Restrepo, Diego Mauricio Gómez, Alejandro Mesa-Urdinola, Andrea Constanza Rubio, Juan Manuel Reyes, Natalia Castaño Gamboa, Jorge Enrique Machado-Alba","doi":"10.1186/s12962-025-00701-0","DOIUrl":"10.1186/s12962-025-00701-0","url":null,"abstract":"","PeriodicalId":47054,"journal":{"name":"Cost Effectiveness and Resource Allocation","volume":" ","pages":"34"},"PeriodicalIF":2.5,"publicationDate":"2026-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12911110/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146044085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-21DOI: 10.1186/s12962-025-00709-6
Diana Mendes, Ahuva Averin, Mark Atwood, Reiko Sato, Andrew Vyse, James Campling, Dhwani Hariharan, Derek Weycker, Tendai Mugwagwa, Jeffrey Vietri
{"title":"Cost-effectiveness and return on investment of 20-valent pneumococcal conjugate vaccine use among adults in England: analysis from the societal perspective.","authors":"Diana Mendes, Ahuva Averin, Mark Atwood, Reiko Sato, Andrew Vyse, James Campling, Dhwani Hariharan, Derek Weycker, Tendai Mugwagwa, Jeffrey Vietri","doi":"10.1186/s12962-025-00709-6","DOIUrl":"10.1186/s12962-025-00709-6","url":null,"abstract":"","PeriodicalId":47054,"journal":{"name":"Cost Effectiveness and Resource Allocation","volume":" ","pages":"31"},"PeriodicalIF":2.5,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12908403/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146020058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-20DOI: 10.1186/s12962-025-00703-y
Gavin Surgey, Brian Adu Asare, Rob Baltussen
{"title":"Health technology assessment in Ghana: the development of the process guidelines using evidence-informed deliberative processes.","authors":"Gavin Surgey, Brian Adu Asare, Rob Baltussen","doi":"10.1186/s12962-025-00703-y","DOIUrl":"https://doi.org/10.1186/s12962-025-00703-y","url":null,"abstract":"","PeriodicalId":47054,"journal":{"name":"Cost Effectiveness and Resource Allocation","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146012621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A systematic review of data sources used for socioeconomic impact assessment of antimicrobial resistance from a One Health perspective: a lack of representative data.","authors":"Chittawan Poonsiri, Jarawee Sukmanee, Dian Faradiba, Kinanti Khansa Chavarina, Annapoorna Prakash, Thunyarat Anothaisintawee, Yu Ting Chen, Ella Nanda Sari, Yewei Xie, Candelyn Yu Pong, Sze Tung Lam, Elaine Lum, Nicholas Graves, Hwee Lin Wee, Yot Teerawattananon","doi":"10.1186/s12962-026-00715-2","DOIUrl":"10.1186/s12962-026-00715-2","url":null,"abstract":"","PeriodicalId":47054,"journal":{"name":"Cost Effectiveness and Resource Allocation","volume":" ","pages":"30"},"PeriodicalIF":2.5,"publicationDate":"2026-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12895782/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145999450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-17DOI: 10.1186/s12962-026-00714-3
Wanmin Su, Ziyun Guan, Xiao Li, Feixiang Chen, Panxu Guo, Chuanxiang Yuan, Peixi Wang
{"title":"Equity in health resource allocation in Guangdong Province, China, from 2013-2021: research based on the Dagum Gini coefficient and exploratory spatial data analysis.","authors":"Wanmin Su, Ziyun Guan, Xiao Li, Feixiang Chen, Panxu Guo, Chuanxiang Yuan, Peixi Wang","doi":"10.1186/s12962-026-00714-3","DOIUrl":"10.1186/s12962-026-00714-3","url":null,"abstract":"","PeriodicalId":47054,"journal":{"name":"Cost Effectiveness and Resource Allocation","volume":" ","pages":"29"},"PeriodicalIF":2.5,"publicationDate":"2026-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12895737/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145994629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cost-effectiveness of lenvatinib plus pembrolizumab as the second-line treatment for advanced endometrial carcinoma.","authors":"Szu-Ting Chiang, Chen-Han Chueh, Yu-Wen Wen, Shao-Chin Chiang, Wai-Hou Li, Yi-Wen Tsai","doi":"10.1186/s12962-025-00711-y","DOIUrl":"https://doi.org/10.1186/s12962-025-00711-y","url":null,"abstract":"","PeriodicalId":47054,"journal":{"name":"Cost Effectiveness and Resource Allocation","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145971457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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