Open Dentistry Journal最新文献_第4页

Antibiotics Efficiency in the Infection Complications Prevention after Third Molar Extraction: A Systematic Review. 抗生素在预防第三磨牙拔除术后感染并发症中的作用：系统性综述。

IF 0.5 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Open Dentistry Journal

Pub Date : 2022-04-18 DOI: 10.3390/dj10040072

Diana Sologova, Ekaterina Diachkova, Ilana Gor, Susanna Sologova, Ekaterina Grigorevskikh, Liana Arazashvili, Pavel Petruk, Svetlana Tarasenko

(1) Background: Antibiotics are used in every medical field including dentistry, where they are used for the prevention of postoperative complications in routine clinical practice during the third molar extraction. (2) Methods: This study is reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The present systematic review aimed to evaluate and systematize the use of antibacterial drugs in order to prevent postoperative complications in outpatient oral surgery for wisdom teeth extraction. We conducted a systematic review using electronic databases such as Medline PubMed, Scopus, and the Cochrane Central Register of Controlled Trials. Considering inclusion and exclusion criteria, we included randomized clinical trials published up to 2021 investigating the antibiotic prescription for third molar extraction. (3) Results: We selected 10 studies after the application of inclusion and exclusion criteria. The results showed that the most widely used antibiotic was amoxicillin both with and without clavulanic acid, in different dosages and duration. There were no statistically significant differences between treatment groups for development of postoperative complications. (4) Conclusions: Based on the analysis of the included studies, penicillin is currently the most widely prescribed group of antibiotics. The widespread use of this antibiotic group can lead to antimicrobial resistance (AMR). Due to increasing prevalence of bacteria resistance to penicillins, clinicians should carefully prescribe these antibiotics and be aware that the widespread use of amoxicillin may do more harm than good for the population.

(1) 背景：抗生素应用于包括牙科在内的各个医学领域，在常规临床实践中用于预防第三磨牙拔除术的术后并发症。(2）方法：本研究根据《系统综述和元分析首选报告项目》（Preferred Reporting Items for Systematic Reviews and Meta-Analyses，PRISMA）进行报告。本系统性综述旨在评估和系统化抗菌药物的使用，以预防智齿拔除门诊口腔手术的术后并发症。我们使用 Medline PubMed、Scopus 和 Cochrane Central Register of Controlled Trials 等电子数据库进行了系统性综述。考虑到纳入和排除标准，我们纳入了截至 2021 年发表的研究第三磨牙拔除术抗生素处方的随机临床试验。(3）结果：根据纳入和排除标准，我们选择了 10 项研究。结果显示，最广泛使用的抗生素是阿莫西林，包括含克拉维酸和不含克拉维酸两种，剂量和持续时间各不相同。在术后并发症的发生方面，不同治疗组之间没有统计学意义上的显著差异。(4) 结论：根据对纳入研究的分析，青霉素是目前处方最广泛的一组抗生素。该类抗生素的广泛使用会导致抗菌药耐药性（AMR）。由于细菌对青霉素类抗生素的耐药性日益普遍，临床医生应谨慎处方这些抗生素，并意识到阿莫西林的广泛使用可能会给人们带来更大的伤害。

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引用次数: 0

Salivary Scca1, Scca2 and Trop2 in Oral Cancer Patients-A Cross-Sectional Pilot Study. 口腔癌患者唾液 Scca1、Scca2 和 Trop2--一项横断面试点研究

IF 0.5 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Open Dentistry Journal

Pub Date : 2022-04-15 DOI: 10.3390/dj10040070

Ivana Karmelić, Ivan Salarić, Ksenija Baždarić, Marko Rožman, Ivan Zajc, Marinka Mravak-Stipetić, Ivona Bago, Davor Brajdić, Jasna Lovrić, Darko Macan

Oral squamous cell carcinoma (OSCC) is frequently diagnosed in the advanced stages. The purpose of this paper is to determine the salivary values of SCCA1, SCCA2 and TROP2 in patients with T1N0M0 OSCC and to compare them with the values obtained from healthy individuals. Unstimulated (UWS) and stimulated (SWS) saliva was sampled from 29 patients with T1N0M0 OSCC and 29 sex- and age-matched healthy individuals. Statistical difference was observed in SCCA1 and SCCA2 levels both in UWS and SWS samples. TROP2 was not measurable in most of the salivary samples. Both SCCA1 and SCCA2 could represent potential biomarkers for the early-stage OSCC. Research on a larger sample and biomarker validation is needed to assess the clinical potential of SCCA1 and SCCA2 in the OSCC early diagnostics.

口腔鳞状细胞癌（OSCC）经常被诊断为晚期。本文旨在测定 T1N0M0 OSCC 患者唾液中的 SCCA1、SCCA2 和 TROP2 值，并将其与健康人的唾液值进行比较。研究人员从 29 名 T1N0M0 OSCC 患者和 29 名性别和年龄匹配的健康人唾液中分别提取了未刺激（UWS）和刺激（SWS）唾液样本。在 UWS 和 SWS 样本中均观察到了 SCCA1 和 SCCA2 水平的统计学差异。大多数唾液样本中测不到 TROP2。SCCA1和SCCA2可能是早期OSCC的潜在生物标志物。要评估SCCA1和SCCA2在OSCC早期诊断中的临床潜力，还需要对更大样本进行研究并对生物标志物进行验证。

引用次数: 0

Dental Students’ Knowledge, Confidence, Ability, and Self-Reported Difficulties in Periodontal Education: A Mixed Method Pilot Study 牙科学生牙周教育的知识、信心、能力和自我报告的困难:一项混合方法的初步研究

IF 1.3 Q3 Dentistry

Open Dentistry Journal

Pub Date : 2022-04-01 DOI: 10.3390/dj10040063

Amirsalar Mofidi, Arnaldo J. Perez, Ida Kornerup, L. Levin, Silvia Ortiz, Hollis Lai, J. Green, Seon-Kyeong Kim, M. P. Gibson

Evidence on periodontal education areas in which students have difficulties and their factors are limited. In this study, third- and fourth-year dental students’ knowledge was assessed as well as their confidence and ability in five periodontal educational areas using a mixed-method approach. A survey was used to collect data related to history-taking, medical examination, diagnosis, treatment planning, and follow-up. Student answers were compared to the consensual answers of an expert panel using the cosine-similarity index (CSI). Descriptive statistics assessed confidence and ability for diagnosis. Semi-structured individual interviews were used to collect data on reported reasons for difficulties in periodontal education. A content analysis was employed to analyze the interview data. Eighteen third- and fourth-year dental students completed the survey and eleven were interviewed. Students’ knowledge was adequate regarding diagnosis and treatment planning. Third-year students’ median CSI were 0.93 and 0.89, respectively. Fourth-year students’ median CSI were 0.9 and 0.93, respectively. Students felt confident in history-taking and examination but lacked confidence and ability in diagnosis and treatment planning. Reported reasons for difficulties in periodontal education were linked to both preclinical and clinical pedagogical issues. Further improvements in preclinical and clinical periodontal education are needed to address students’ lack of knowledge, confidence, and skills in key periodontal areas.

在牙周教育方面，学生有困难的领域及其因素的证据是有限的。在这项研究中，采用混合方法评估了三年级和四年级牙科学生在五个牙周教育领域的知识以及他们的信心和能力。通过问卷调查收集有关病史、医学检查、诊断、治疗计划和随访的资料。使用余弦相似指数(CSI)将学生的答案与专家小组的共识答案进行比较。描述性统计评估了诊断的信心和能力。采用半结构化的个人访谈来收集有关牙周教育困难的报告原因的数据。采用内容分析法对访谈数据进行分析。18名三年级和四年级的牙科学生完成了调查，其中11人接受了采访。学生对诊断和治疗方案的认识是足够的。三年级学生的CSI中位数分别为0.93和0.89。四年级学生的CSI中位数分别为0.9和0.93。学生对病史和考试有信心，但对诊断和治疗计划缺乏信心和能力。报道的牙周教育困难的原因与临床前和临床教学问题有关。临床前和临床牙周教育需要进一步改进，以解决学生在牙周关键领域缺乏知识、信心和技能的问题。

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引用次数: 1

Resin Cement Residue Removal Techniques: In Vitro Analysis of Marginal Defects and Discoloration Intensity Using Micro-CT and Stereomicroscopy 树脂水泥残渣去除技术:微ct和体视显微镜对边缘缺陷和变色强度的体外分析

IF 1.3 Q3 Dentistry

Open Dentistry Journal

Pub Date : 2022-04-01 DOI: 10.3390/dj10040055

Mara Gaile, E. Papia, Vita Zalite, J. Locs, U. Soboleva

The objective was to compare marginal defects and evaluate discoloration for adhesively cemented veneers in vitro when using two cement removal techniques. Twenty premolars were prepared with chamfer and borders in enamel. IPS e.max CAD veneers were cemented using Panavia V5 and divided in two groups (n = 10): cement excess removed with a probe after tack-curing for 3–5 s, or cement excess removed with a brush, then completely polymerized. All teeth were stored in alginate gel until micro-CT examination. Scanning was performed twice: directly after cementation and after thermocycling (5000 cycles, between 5 and 55 °C). To analyze discoloration, teeth were colored using 0.5% basic fuchsine and examined under a stereomicroscope. Depth of dye infiltration was scored 0 (no discoloration) to 5 (discoloration along the entire margin). Statistically significant differences of cement defects before thermocycling were reported, where brushing showed more defects than probing (p = 0.0161). After thermocycling, the defects increased for both groups. Extensive discoloration was the most common (55.56%) when removing excess by probing; by brushing, 90% of the specimens exhibited slight discoloration (p = 0.008). Regression analysis showed no relationship between type of defect and degree of discoloration. Removing cement with a brush causes more marginal defects, however less discoloration after thermocycling.

目的是比较边缘缺陷和评估变色粘接胶结单板在体外使用两种水泥去除技术。预备前磨牙20颗，牙釉质有倒角和边。使用Panavia V5胶结IPS e.max CAD贴面，并分为两组(n = 10):在胶粘固化3-5 s后用探针去除多余的水泥，或用刷子去除多余的水泥，然后完全聚合。所有牙齿保存在海藻酸盐凝胶中，等待显微ct检查。扫描进行了两次:胶结后直接扫描和热循环后扫描(5000次循环，在5到55°C之间)。为了分析变色情况，用0.5%的碱性品红给牙齿上色，并在体视显微镜下进行检查。染料浸润深度评分为0(无变色)至5(整个边缘变色)。在热循环前报告的水泥缺陷有统计学意义的差异，其中刷牙比探针显示更多的缺陷(p = 0.0161)。热循环后，两组的缺陷均有所增加。当用探针去除多余部分时，广泛变色最为常见(55.56%);通过刷牙，90%的标本出现轻微变色(p = 0.008)。回归分析显示缺损类型与变色程度无相关性。用刷子去除水泥会导致更多的边缘缺陷，但热循环后变色较少。

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引用次数: 1

Perceived Didactic Curricular Effectiveness of In-Person vs. Virtual Formats amongst Fourth-Year Dental Students 四年级牙科学生对面对面教学与虚拟教学课程有效性的感知

IF 1.3 Q3 Dentistry

Open Dentistry Journal

Pub Date : 2022-04-01 DOI: 10.3390/dj10040060

Robert D. Bowers, L. B. Young, C. Comnick, Hariyali Kasundra, Christopher A. Barwacz

Purpose: The COVID-19 pandemic altered the methodologies of dental education delivery, resulting in both immediate and more enduring changes. To assess student perceptions of learning effectiveness, graduating dental students from the class of 2020 were surveyed to identify student comfort with technology and content retention, individual motivation and mental focus, and access to resources pertaining to an abrupt transition to a virtual learning didactic seminar approach in March 2020. Methods: a voluntary, 18-question electronic survey was distributed to fourth-year dental students prior to graduation to assess perceptions of learning outcomes and preferences of a virtual seminar format relative to previous in-person didactic seminars experienced. Results: 34 of 80 dental students (42.5%) completed the electronic survey. Comfort and retention of concepts through virtual learning were reported ≥ by 91% and 85% of the respondents, respectively. Increased distractions and multitasking were reported with virtual learning in 56% and 71%, respectively. Desires to have all teaching conducted through virtual learning platforms was reported at 21%. Conclusions: the positive student responses obtained when comparing virtual to in-person seminars in the survey assessment demonstrates the long-term potential for such delivery modalities to be intentionally incorporated into an evolving predoctoral curriculum in a hybrid nature.

目的:2019冠状病毒病大流行改变了牙科教育提供的方法，导致了即时和更持久的变化。为了评估学生对学习效果的看法，我们对2020届毕业的牙科学生进行了调查，以确定学生对技术和内容保留、个人动机和精神焦点的舒适度，以及与2020年3月突然过渡到虚拟学习教学研讨会方法相关的资源获取情况。方法:对毕业前的四年级牙科学生进行了一项自愿的、包含18个问题的电子调查，以评估他们对学习成果的看法，以及相对于之前经历过的面对面教学研讨会而言，虚拟研讨会形式的偏好。结果:80名牙科学生中有34人(42.5%)完成了电子调查。91%和85%的受访者分别报告了通过虚拟学习对概念的舒适和保留。分别有56%和71%的人报告说虚拟学习增加了分心和多任务处理。21%的人希望所有的教学都能通过虚拟学习平台进行。结论:在调查评估中，当比较虚拟研讨会和面对面研讨会时，获得的积极学生反应表明，这种交付方式有意地以混合性质纳入不断发展的博士前课程的长期潜力。

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引用次数: 0

Effects of Fermented Lingonberry Juice Mouthwash on Salivary Parameters—A One-Year Prospective Human Intervention Study 发酵越橘汁漱口水对唾液参数的影响——一项为期一年的前瞻性人为干预研究

IF 1.3 Q3 Dentistry

Open Dentistry Journal

Pub Date : 2022-04-01 DOI: 10.3390/dj10040069

Pirjo Pärnänen, Sari Lomu, Ismo T. Räisänen, T. Tervahartiala, T. Sorsa

A one-year prospective human intervention study was performed to examine the effects of fermented lingonberry juice (FLJ), used as a mouthwash for six months, on salivary parameters. A total of 25 adult participants used 10 mL of FLJ as mouthwash 30 s daily for 6 months in addition to their normal oral homecare routines. Standard oral examinations and gathering of samples were performed at the beginning of the study and after six months and one year. Resting and stimulated saliva secretion rates, resting saliva pH, and stimulated saliva buffering capacity were determined. A questionnaire of participants’ subjective sensations of mouth dryness was also recorded at each timepoint. Fermented lingonberry juice mouthwash had positive effect to all five salivary parameters and were, according to the omnibus test, statistically significant during the study period. Analysis of the subjective dry mouth sensation questionnaires revealed that symptoms of xerostomia decreased due to the use of FLJ. This study revealed that the once-a-day use of FLJ mouthwash had a beneficial, increasing effect on salivary flow rates, buffering capacity, and salivary pH. FLJ thus can be safely used as an adjunctive and beneficial therapy in oral homecare, protecting teeth and oral mucosa, including periodontium, and also relieving dry mouth symptoms.

一项为期一年的前瞻性人类干预研究进行了检查发酵越橘汁(FLJ)的影响，作为漱口水使用了六个月，对唾液参数。共有25名成年参与者在他们正常的口腔家庭护理程序之外，每天30次使用10毫升FLJ作为漱口水，持续6个月。在研究开始时、六个月后和一年后进行标准的口腔检查和样本收集。测定静息和刺激唾液分泌率、静息唾液pH值和刺激唾液缓冲能力。参与者在每个时间点的主观口干感觉的问卷也被记录下来。发酵越橘汁漱口水对所有五项唾液参数均有积极影响，根据综合检验，在研究期间具有统计学意义。对主观口干感觉问卷的分析显示，使用FLJ后，口干症状有所减轻。本研究显示，每天一次使用FLJ漱口水对唾液流速、缓冲能力和唾液ph有有益的增加作用。因此，FLJ可以安全地用作口腔家庭护理的辅助和有益的治疗，保护牙齿和口腔黏膜，包括牙周组织，并缓解口干症状。

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引用次数: 4

Stress Concentration of Hybrid Occlusal Splint-Mouthguard during a Simulated Maxillofacial Traumatic Impact: 3D-FEA 复合咬合夹板-护齿在模拟颌面部创伤冲击中的应力集中:3D-FEA

IF 1.3 Q3 Dentistry

Open Dentistry Journal

Pub Date : 2022-04-01 DOI: 10.3390/dj10040065

João Paulo Mendes Tribst, A. D. Dal Piva, Les Kalman

Mouthguards (MG) are protective devices that can reduce the risks of facial trauma. However, many athletes do not use them. Additionally, MG wear with coincidental parafunctional activity has not been considered. The aim of this study was to evaluate the stress distribution as a consequence of a direct impact comparing a conventional MG with a novel hybrid appliance (HMG). Using computer-aided design (CAD) software, a human skull was modeled with the teeth inserted into their respective alveolus. The models were divided according to the MG type (conventional or hybrid). The geometries were exported to the computer-aided engineering (CAE) software and the materials were considered isotropic. Fixation was defined at the base of the maxilla. The load was applied using a hockey puck. The total deformation (mm) and the von Mises stress (MPa) results were obtained for the MGs (conventional and hybrid), upper teeth, lower teeth, and maxillary bone. Despite the presence of an MG, it is still possible to observe generated stress in all structures. However, the hybrid design was more efficient than the conventional design in reducing the displacement during the impact and consequently the stress on the upper teeth, lower teeth, and maxillary bone. Higher stress magnitude was more concentrated at the inner portion of the hybrid design than the conventional device. The HMG appliance decreased the stress concentration in the teeth and in the bone, limiting the areas susceptible to injuries to the regions directly impacted by the hockey puck. Although the novel HMG may mitigate injury, some stress will still result, and any possible injury should be evaluated by a dental professional.

护齿器(MG)是一种可以降低面部创伤风险的保护装置。然而，许多运动员并不使用它们。此外，MG佩戴与巧合的功能活动没有被考虑。本研究的目的是比较传统MG和新型混合矫治器(HMG)在直接冲击下的应力分布。利用计算机辅助设计(CAD)软件，将牙齿插入到各自的牙槽中，建立了人类头骨模型。车型根据MG类型(常规或混合)进行划分。几何图形导出到计算机辅助工程(CAE)软件中，材料被认为是各向同性的。固定在上颌骨底部。这个负荷是用冰球施加的。分别对常规牙和混合牙、上牙、下牙和上颌骨进行了总变形(mm)和von Mises应力(MPa)测量。尽管存在MG，但仍有可能观察到所有结构中产生的应力。然而，混合设计比传统设计更有效地减少了碰撞时的位移，从而减少了对上牙、下牙和上颌骨的应力。与常规装置相比，混合结构设计中较高的应力量级更集中在内部。HMG矫治器降低了牙齿和骨骼的应力集中，将易受伤的区域限制在冰球直接影响的区域。尽管新型HMG可以减轻损伤，但仍然会产生一些压力，任何可能的损伤都应该由牙科专业人员进行评估。

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引用次数: 1

The Stockholm Study: Over 30 years’ Observation of the Effect of Oral Infections on Systemic Health 斯德哥尔摩研究:对口腔感染对全身健康影响的30多年观察

IF 1.3 Q3 Dentistry

Open Dentistry Journal

Pub Date : 2022-04-01 DOI: 10.3390/dj10040068

J. Meurman, B. Söder

The Stockholm Studies are a series of investigations started in 1985 and still ongoing. Out of 105,798 inhabitants, aged 30 and 40 years and living in the greater Stockholm area in Sweden, 3273 subjects were randomly selected. Of them, 1676 were clinically examined focusing on oral health. The subjects were then followed up using national population and health registers in order to study associations between oral health parameters and systemic health outcomes and finally death. The 35 years of observation provides unique possibilities to analyze, for example, how periodontitis links to a number of systemic health issues. The results have consequently provided numerous new associations and confirmed earlier observations on how poor oral health is associated with heart diseases and cancer.

斯德哥尔摩研究是1985年开始的一系列调查，目前仍在进行中。在105,798名年龄在30岁和40岁之间、居住在瑞典大斯德哥尔摩地区的居民中，随机选择了3273名受试者。其中1676人接受了口腔健康方面的临床检查。然后使用国家人口和健康登记册对受试者进行随访，以研究口腔健康参数与全身健康结果和最终死亡之间的关系。35年的观察为分析提供了独特的可能性，例如，牙周炎如何与许多全身健康问题联系起来。因此，研究结果提供了许多新的关联，并证实了早期关于口腔健康状况不佳与心脏病和癌症之间关系的观察结果。

引用次数: 1

Trusting the Dentist—Expecting a Leap of Faith vs. a Well-Defined Strategy for Anxious Patients 信任牙医——期待信心的飞跃vs.焦虑患者的明确策略

IF 1.3 Q3 Dentistry

Open Dentistry Journal

Pub Date : 2022-04-01 DOI: 10.3390/dj10040066

Rod Moore

This article aimed to set into perspective the unique aspects of trust within the dentist–patient relationship by exploring the literature as well as historical aspects of dentistry in the association between trust/distrust and patient anxiety. In order to characterise this uniqueness, the assumptions for trusting in dentistry are compared and contrasted with other professions using a conceptual analysis. The professions of medicine, sociology, psychology, nursing and dentistry were check listed according to the tenets of a concept analytical approach reported by Hupcey et al., in 2001. Recommendations for patient/person-centred care, as opposed to dentist-centred care, that would improve trust are specified according to the literature. These include empowering patients, practicing active listening, empathy and relationship building that might benefit dental patients in relation to the perceived risks of anxiety or induced pain. It was concluded that global distrust of dominating dentists must give way to person-centred professional strategies so that dentists and patients can tackle their dental anxiety-trust challenges, both in the public’s image of the dental profession and in clinical relationships. Future directions would be to explore incentives for dentists to change to patient/person-centred care.

本文旨在通过探索文献以及牙科在信任/不信任与患者焦虑之间的关联的历史方面，来了解牙医与患者关系中信任的独特方面。为了描述这种独特性，使用概念分析将信任牙科的假设与其他职业进行比较和对比。根据hupsey等人2001年报告的概念分析方法的原则，对医学、社会学、心理学、护理和牙科等专业进行了检查。建议患者/以人为中心的护理，而不是以牙医为中心的护理，这将提高信任，根据文献指定。这些措施包括赋予患者权力，练习积极倾听，移情和建立关系，这些可能有利于牙科患者感知焦虑或诱发疼痛的风险。结论是，全球对占主导地位的牙医的不信任必须让位于以人为本的专业策略，这样牙医和患者才能解决他们的牙科焦虑-信任挑战，无论是在公众对牙科专业的形象还是在临床关系中。未来的方向将是探索激励牙医转变为以病人/人为中心的护理。

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引用次数: 3

Lipid Profiles and Cardiovascular Risk in Patients with Oral Lichen Planus 口腔扁平苔藓患者的脂质特征和心血管风险

IF 1.3 Q3 Dentistry

Open Dentistry Journal

Pub Date : 2022-04-01 DOI: 10.3390/dj10040061

T. Radić, L. Cigić, A. Glavina, Ana Hrboka, Ana Druzijanic, Ivona Musa Leko, D. Biočina-Lukenda

Background: It has been reported that dyslipidemia prevalence and cardiovascular disease risk were increased in subjects with oral lichen planus diagnose. On the other hand, so far, there is no available data on the topic of cardiovascular risk (CVR) in subjects with oral lichen planus (OLP). The main aim of this study, due to lack of any other study covering this topic, was to investigate lipid profile and assess CVR in patients with OLP. Materials and Methods: To create a routine lipid profile, we collected triglyceride serum levels, total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol from 63 OLP patients and 63 healthy people representing control subjects. For every patient their individual cardiovascular risk was measured. Results: In comparison with the tested control subjects, patients with OLP had all parameters of the lipid profile elevated, with no differences of statistical importance. Furthermore, the experimental (OLP) and control groups shared similar mean values of the lipid profile parameters. Conclusions: The association of OLP with cardiovascular risk was not established and further studies with more subjects involved are required to validate this connection.

背景:据报道，诊断为口腔扁平苔藓的受试者血脂异常患病率和心血管疾病风险增加。另一方面，到目前为止，还没有关于口腔扁平苔藓(OLP)受试者心血管风险(CVR)的可用数据。由于缺乏其他涉及该主题的研究，本研究的主要目的是调查OLP患者的脂质状况并评估CVR。材料和方法:为了建立常规血脂，我们收集了63例OLP患者和63名健康对照者的血清甘油三酯水平、总胆固醇、低密度脂蛋白胆固醇和高密度脂蛋白胆固醇。对每位患者的心血管风险进行了测量。结果:与对照组比较，OLP患者血脂各项指标均升高，差异无统计学意义。此外，实验组(OLP)和对照组的血脂参数平均值相似。结论:OLP与心血管风险的关联尚未建立，需要更多受试者参与的进一步研究来验证这种关联。

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引用次数: 3