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Pulmonary Nodule in a Patient with Oral and Lung Cancer: Cryptococcus Infection 口腔癌和肺癌患者的肺结节:隐球菌感染
IF 1.3 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2019-10-23 DOI: 10.3390/dj7040102
K. Yamagata, Chikako Hirano, N. Kanno, F. Uchida, S. Fukuzawa, T. Yanagawa, H. Bukawa
Pulmonary nodules are frequently considered to be a metastatic disease or primary lung tumors in oral cancer patients. We present a case of pulmonary cryptococcosis in a 68-year-old man with oral and lung cancer. This lung cancer was treated with thoracoscopic resection of the right inferior lobe and mediastinal lymph node dissection. Lower gingival cancer was treated with a mandibulectomy, neck dissection, and reconstruction after chemoradiotherapy. A 20 mm cavitary nodule appeared at the left lung S6 one-month after surgery, during post-operative computed tomography. Thoracoscopic partial resection of the left inferior lobe was performed under the suspicion of lung metastasis. Pathology results revealed a pseudo-epithelial granuloma with necrosis and many yeast-shaped fungi with capsules. A pathological diagnosis of Cryptococcus infection was made. The patient was prescribed the antifungal agent fosfluconazole, which was administered intravenously for 1 week and intraoral fluconazole for 12 months. No recurrence of the Cryptococcus infection has been noted after 1.5 years.
在口腔癌患者中,肺结节常被认为是一种转移性疾病或原发性肺肿瘤。我们报告一例68岁男性伴有口腔癌和肺癌的肺隐球菌病。本例肺癌经胸腔镜右下叶切除及纵隔淋巴结清扫术治疗。下龈癌的治疗是下颌骨切除术,颈部清扫,放化疗后重建。术后计算机断层扫描显示,术后1个月左肺S6处出现20毫米空洞结节。在怀疑肺转移的情况下,行胸腔镜下左下叶部分切除术。病理结果显示假上皮肉芽肿伴坏死及许多酵母状真菌带囊。病理诊断为隐球菌感染。患者给予抗真菌药物氟康唑静脉滴注1周,氟康唑口服12个月。术后1年半未见隐球菌感染复发。
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引用次数: 1
Survival of a Maxillary Incisor in an Adolescent Male 16 Years after Its Delayed Replantation 青少年男性上颌切牙延迟再植16年后的存活率
IF 1.3 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2019-10-16 DOI: 10.3390/dj7040101
R. Biagi, V. Maccagnola
Introduction: Recreational and sport activities, traffic accidents and human behaviour represent the main causes of trauma in young people. Case presentation: This report describes a case of a 15.2-year-old male who suffered uncomplicated crown fracture and avulsion of tooth 11 and uncomplicated crown fracture of tooth 21 due to a bicycle accident. Tooth 11 was dry stored and it was replanted 18 h after the trauma. The root was planed to remove the necrotic periodontal tissue, the pulp was extirpated before replantation and a flexible splint was applied to tooth 13 to tooth 23 for 3 weeks. A replacement root resorption of replanted tooth was suspected at the 3-month radiographic control and suffered a dramatic increase later; minimal infraocclusion, about 1 mm, was observed due to its ankylosis. Sixteen years after the trauma the patient was scheduled for an orthodontic and implanto-prosthetic rehabilitation. Conclusion: Delayed replantation usually has a long-term poor prognosis, so it is very important to promote awareness regarding emergency management modalities in dental traumatology especially among parents, school teachers, and coaches that are usually present at the site of the accident.
引言:娱乐和体育活动、交通事故和人类行为是造成青少年创伤的主要原因。病例介绍:本报告报告一名15.2岁男性,因自行车事故导致第11牙无并发症冠骨折及撕脱,第21牙无并发症冠骨折。11号牙干燥保存,创伤后18小时再植。将牙根刨平以去除坏死的牙周组织,在再植前拔除牙髓,并在牙13至牙23上使用柔性夹板3周。在3个月的x线检查中怀疑再植牙的替代根吸收,并在之后急剧增加;由于其强直,观察到最小的下咬合,约1mm。创伤后16年,病人被安排进行正畸和种植修复康复。结论:延后再植的远期预后较差,因此提高牙外伤患者的应急管理意识是非常重要的,尤其是在事故现场的家长、学校教师和教练员中。
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引用次数: 7
Self-Reported Changes in Oral Hygiene Habits among Adolescents Receiving Orthodontic Treatment 接受正畸治疗的青少年口腔卫生习惯的自我报告变化
IF 1.3 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2019-10-01 DOI: 10.3390/dj7040096
Sandra Petrauskienė, Natalia Wanczewska, Eglė Slabšinskienė, G. Žemgulytė
The prevalence of malocclusion and a need for orthodontic treatment is high. Orthodontic appliances increase biofilm accumulation by expanding plaque retention sites. The aim of this study was to investigate the self-reported changes in oral hygiene habits among adolescents receiving orthodontic treatment. A cross-sectional study of 291 patients aged 10–17 years (mean (M) = 12.98; standard deviation (SD) = 2.36) was conducted in the Department of Orthodontics, Lithuanian University of Medical Sciences (LSMU) Hospital (Kaunas, Lithuania) during the fall semester (October–January) of the 2017/2018 study year. An anonymous self-administered questionnaire covered background information, experience of orthodontic treatment, oral hygiene habits and the seeking of professional dental care. Statistical data analysis was performed using SPSS version 22. To establish relationships between categorical variables, Chi-squared tests (χ2) were used. A p-value ≤ 0.05 was set to indicate statistically significant difference. The univariate logistic regression analysis evaluated the probability of an event given a certain risk indicator, including odds ratio (OR) and its confidence interval (95% CI). Associations were found between the usage of auxiliary measures (OR = 1.797 (1.118–2.887), p = 0.015), tongue cleaning (OR = 1.712 (1.059–2.767), p = 0.028), mouth rinsing after meals (OR = 1.707 (1.048–2.781), p = 0.032) and experience of orthodontic treatment, respectively. More orthodontic patients underwent professional oral hygiene regularly than non-orthodontic patients (p = 0.024). More patients with fixed orthodontic appliances reported significantly changed oral hygiene habits, while more orthodontic patients with removable appliances did not change their oral hygiene habits.
错牙合的患病率和正畸治疗的需求很高。正畸器具通过扩大牙菌斑保留位点增加生物膜的积累。本研究的目的是调查接受正畸治疗的青少年自我报告的口腔卫生习惯的变化。291例10-17岁患者的横断面研究(平均(M) = 12.98;标准偏差(SD) = 2.36)于2017/2018研究年度秋季学期(10 - 1月)在立陶宛医学大学(LSMU)医院(考纳斯,立陶宛)正畸科进行。一份不记名的自我调查问卷涵盖了背景信息、正畸治疗经历、口腔卫生习惯和寻求专业牙科护理。统计数据分析采用SPSS 22。为建立分类变量之间的关系,采用χ2检验。p值≤0.05表示差异有统计学意义。单变量逻辑回归分析评估给定特定风险指标的事件发生概率,包括优势比(OR)及其置信区间(95% CI)。辅助措施的使用(OR = 1.797 (1.118 ~ 2.887), p = 0.015)、清洁舌部(OR = 1.712 (1.059 ~ 2.767), p = 0.028)、餐后漱口(OR = 1.707 (1.048 ~ 2.781), p = 0.032)与正畸治疗经验相关。正畸患者定期进行专业口腔卫生检查的比例高于非正畸患者(p = 0.024)。固定式矫治器患者口腔卫生习惯有明显改变的患者较多,而移动式矫治器患者口腔卫生习惯无明显改变的患者较多。
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引用次数: 6
Q-Switch Nd:YAG Laser-Assisted Decontamination of Implant Surface q开关Nd:YAG激光辅助种植体表面去污
IF 1.3 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2019-10-01 DOI: 10.3390/dj7040099
M. Namour, Marwan El Mobadder, D. Magnin, A. Peremans, T. Verspecht, W. Teughels, L. Lamard, S. Nammour, E. Rompen
Peri-implantitis (PI) is an inflammatory disease of peri-implant tissues, it represents the most frequent complication of dental implants. Evidence revealed that microorganisms play the chief role in causing PI. The purpose of our study is to evaluate the cleaning of contaminated dental implant surfaces by means of the Q-switch Nd:YAG (Neodymium-doped Yttrium Aluminum Garnet) laser and an increase in temperature at lased implant surfaces during the cleaning process. Seventy-eight implants (titanium grade 4) were used (Euroteknika, Sallanches, France). Thirty-six sterile implants and forty-two contaminated implants were collected from failed clinical implants for different reasons, independent from the study. Thirty-six contaminated implants were partially irradiated by Q-switch Nd:YAG laser (1064 nm). Six other contaminated implants were used for temperature rise evaluation. All laser irradiations were calibrated by means of a powermetter in order to evaluate the effective delivered energy. The irradiation conditions delivered per pulse on the target were effectively: energy density per pulse of 0.597 J/cm2, pick powers density of 56 mW/cm2, 270 mW per pulse with a spot diameter of 2.4 mm, and with repetition rate of 10 Hz for pulse duration of 6 ns. Irradiation was performed during a total time of 2 s in a non-contact mode at a distance of 0.5 mm from implant surfaces. The parameters were chosen according to the results of a theoretical modeling calculation of the Nd:YAG laser fluency on implant surface. Evaluation of contaminants removal showed that the cleaning of the irradiated implant surfaces was statistically similar to those of sterile implants (p-value ≤ 0.05). SEM analysis confirmed that our parameters did not alter the lased surfaces. The increase in temperature generated at lased implant surfaces during cleaning was below 1 °C. According to our findings, Q-switch Nd:YAG laser with short pulse duration in nanoseconds is able to significantly clean contaminated implant surfaces. Irradiation parameters used in our study can be considered safe for periodontal tissue.
种植体周围炎(PI)是种植体周围组织的炎症性疾病,是种植体最常见的并发症。有证据表明,微生物在引起PI中起主要作用。我们的研究目的是评估使用q开关Nd:YAG(掺钕钇铝石榴石)激光器对受污染种植体表面的清洁效果,以及在清洁过程中激光种植体表面温度的升高。使用了78个种植体(钛级4)(Euroteknika, Sallanches, France)。36个无菌种植体和42个污染种植体来自于不同原因的临床失败种植体,独立于研究。用q开关Nd:YAG激光(1064 nm)局部照射36个污染植体。另外6个受污染的植入物用于温升评估。所有的激光照射都是通过功率计校准的,以便评估有效传递的能量。每脉冲照射目标的有效条件为:每脉冲能量密度0.597 J/cm2,拾取功率密度56 mW/cm2, 270 mW/脉冲,光斑直径2.4 mm,重复频率10 Hz,脉冲持续时间6 ns。在距离种植体表面0.5 mm的距离处,以非接触方式照射,总时间为2 s。根据Nd:YAG激光在植入体表面的流畅度的理论建模计算结果选择参数。污染物去除率评估显示,辐照种植体表面的清洁度与无菌种植体的清洁度在统计学上相似(p值≤0.05)。扫描电镜分析证实,我们的参数没有改变激光表面。在清洗过程中,激光植入物表面产生的温度升高低于1°C。根据我们的研究结果,短脉冲持续时间(纳秒)的q开关Nd:YAG激光器能够显著清洁受污染的植入物表面。在我们的研究中使用的辐照参数可以被认为是安全的牙周组织。
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引用次数: 13
Integrated Digital and Conventional Treatment Workflow in Guided Complete Mouth Implant Rehabilitation: A Clinical Case Report 综合数字化与传统治疗流程在全口种植康复中的应用:一个临床病例报告
IF 1.3 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2019-10-01 DOI: 10.3390/dj7040100
Jason D. Lee, Soomin Jung, Chin‐Wei Wang, Sang J. Lee
Clinical Implications The integration of both conventional and digital techniques in the treatment workflow can have a synergistic effect that facilitates the treatment of complex complete mouth prosthetic rehabilitations. Abstract The introduction of digital dentistry and CAD/CAM technology has redefined treatment concepts in implant dentistry—computer guided implant placement has become routine practice, and CAD/CAM prostheses are now commonplace. These advances in treatment options and modalities has led to a paradigm shift in the workflow of surgical and restorative treatments. This case report presents a customized staged treatment protocol that involves the strategic retention of teeth to serve as transitional abutments, which will support a computer guided implant surgical guide as well as a fixed interim prosthesis. The treatment protocol also describes an integrated digital and conventional workflow for full mouth implant-supported fixed prosthetic rehabilitations to provide improved patient care with more predictable outcomes and fewer complications.
在治疗流程中整合传统技术和数字技术可以产生协同效应,促进复杂的全口假体康复治疗。数字牙科和CAD/CAM技术的引入重新定义了种植牙科的治疗概念-计算机引导种植体放置已成为常规做法,CAD/CAM假体现已司空见惯。这些治疗选择和方式的进步导致了手术和恢复性治疗工作流程的范式转变。本病例报告提出了一种定制的分阶段治疗方案,包括策略性保留牙齿作为过渡基台,它将支持计算机引导的种植手术指南以及固定的临时假体。该治疗方案还描述了全口种植支持的固定假体康复的集成数字和传统工作流程,以提供更好的患者护理,更可预测的结果和更少的并发症。
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引用次数: 2
The Psychological Impact of Dental Aesthetics in Patients with Juvenile Idiopathic Arthritis Compared with Healthy Peers: A Cross-Sectional Study 青少年特发性关节炎患者与健康同龄人比较牙科美学的心理影响:一项横断面研究
IF 1.3 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2019-10-01 DOI: 10.3390/dj7040098
R. Bucci, R. Rongo, A. Amato, S. Martina, V. D’antò, R. Valletta
This study aimed to assess whether dental aesthetics had a different impact on the psychosocial domains of adolescents with juvenile idiopathic arthritis (JIA) as compared with healthy peers. Fifty JIA patients and eighty controls aged between 13 and 17 years were enrolled. The Psychosocial Impact of Dental Aesthetics Questionnaire (PIDAQ) was administered along with tools for the self-assessment of malocclusion and self-esteem. An objective evaluation of malocclusion severity was performed through a clinical evaluation with the Dental Aesthetic Index (DAI). The sample was divided according to the DAI stages of malocclusion severity; a two-way analysis of variance (ANOVA) was performed to assess whether there was a difference in the studied variables according to the malocclusion and the presence of JIA. The results showed no interaction between the malocclusion severity and the presence of JIA in all analyzed variables (all p > 0.05). According to the DAI stages, the Dental Self-Confidence domain of the PIDAQ and the Perception of Occlusion Scale showed statistically significant differences only within the controls (p = 0.027 and p = 0.014, respectively). Therefore, JIA adolescents seem to be less concerned about their dental aesthetics compared with healthy peers, and clinicians should take particular care when proposing orthodontic treatments aiming only to improve dental aesthetics.
本研究旨在评估牙齿美学对青少年特发性关节炎(JIA)患者的心理社会领域的影响是否与健康同龄人不同。50例JIA患者和80例对照组,年龄在13 - 17岁之间。采用口腔美学心理社会影响问卷(PIDAQ)与错颌和自尊的自我评估工具一起进行。采用牙美容指数(DAI)进行临床评价,客观评价错牙合严重程度。按DAI错牙合严重程度分期进行分类;采用双向方差分析(ANOVA)来评估根据错颌和JIA的存在,所研究的变量是否存在差异。结果显示,所有分析变量中,错颌严重程度与JIA的存在无交互作用(均p > 0.05)。根据DAI的分期,PIDAQ和咬合感知量表的牙齿自信域仅在对照组内有统计学差异(p = 0.027和p = 0.014)。因此,与健康同龄人相比,JIA青少年似乎不太关心他们的牙齿美观,临床医生在建议仅以改善牙齿美观为目的的正畸治疗时应特别小心。
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引用次数: 5
Educational Attainment and Self-Rated Oral Health among American Older Adults: Hispanics’ Diminished Returns 美国老年人的受教育程度和自评口腔健康:西班牙裔减少回报
IF 1.3 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2019-10-01 DOI: 10.3390/dj7040097
S. Assari, M. Bazargan
Background: Minorities’ diminished returns (MDRs) refer to systemically weaker effects of socioeconomic status (SES), particularly educational attainment, on the health of non-Whites compared to Whites. Aim: Using a nationally representative sample, we aimed to investigate ethnic differences in the effect of SES (educational attainment) on the self-rated oral health of Hispanic older adults in the US. Methods: This study analyzed the University of Michigan National Poll on Healthy Aging (UM-NPHA) 2017 data, which included 2131 older adults who were 50 to 80 years old (202 Hispanics and 1929 non-Hispanics). Ethnicity, race, educational attainment (SES), age, gender, employment, retirement, and self-rated oral health (single item) were measured. Logistic regressions were applied for data analysis. Results: High educational attainment was associated with lower odds of poor oral health in the pooled sample, net of all covariates. The effect of educational attainment on poor self-rated oral health was found to be weaker for Hispanics than for non-Hispanics. Conclusion: We observed MDRs of educational attainment (SES) on oral health for Hispanic older adults. In other words, compared to non-Hispanics, Hispanics gain less oral health from their educational attainment (SES).
背景:与白人相比,少数族裔的收益减少(mdr)是指社会经济地位(SES)对非白人健康的系统性影响较弱,尤其是受教育程度。目的:使用具有全国代表性的样本,我们旨在调查美国西班牙裔老年人SES(受教育程度)对自评口腔健康影响的种族差异。方法:本研究分析了密歇根大学2017年健康老龄化全国民意调查(UM-NPHA)的数据,其中包括2131名50至80岁的老年人(202名西班牙裔和1929名非西班牙裔)。测量民族、种族、受教育程度(SES)、年龄、性别、就业、退休和自评口腔健康(单项)。采用Logistic回归进行数据分析。结果:在所有协变量中,较高的受教育程度与较低的口腔健康不良几率相关。受教育程度对西班牙裔自评口腔健康不良的影响要弱于非西班牙裔。结论:我们观察了西班牙裔老年人受教育程度(SES)对口腔健康的影响。换句话说,与非西班牙裔美国人相比,西班牙裔美国人受教育程度(SES)对口腔健康的影响更小。
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引用次数: 13
Flowable Bulk-Fill Materials Compared to Nano Ceramic Composites for Class I Cavities Restorations in Primary Molars: A Two-Year Prospective Case-Control Study 流动体填充材料与纳米陶瓷复合材料在初生磨牙I类蛀牙修复中的比较:一项为期两年的前瞻性病例对照研究
IF 1.3 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2019-09-25 DOI: 10.3390/dj7040094
M. Sarapultseva, Alexey Sarapultsev
Background: The aim of this split-mouth study is to compare the results of 24 months’ clinical performance of primary molar Class I restorations with a nano-ceramic composite, Ceram•X mono (Dentsply) with a flowable bulk-fill material regular viscosity, SDR (Dentsply). Methods: Following the ethical approval, 27 patients with at least two class I cavities in primary molars were included in the study. A total number of 54 restorations were conducted (n = 27 for Ceram X and n = 27 for SDR). Restorations were evaluated at baseline, 6, 18, and 24 months, according to the modified Ryge criteria. The cavosurface marginal discoloration and color match were evaluated visually after air-drying the tooth and after removing the plaque (if necessary). Results: At 24 months’ follow-up, 54 restorations showed similar clinical performance. The statistical analysis did not reveal any statistical significance in the values between the groups in 7 out of 7 modified Ryge criteria. However, two restorations in both groups received Bravo ratings in the cavosurface marginal discoloration scoring. No side effects were reported by the participants of the study. Conclusion: Restorations with both materials (Ceram•X mono and SDR) have provided almost identical results.
背景:本裂口研究的目的是比较纳米陶瓷复合材料Ceram•X mono (Dentsply)和可流动填充材料SDR (Dentsply)的初级磨牙I类修复体24个月的临床表现。方法:27例初生磨牙至少有2个I类牙槽的患者,经伦理批准纳入研究。共进行了54例修复(Ceram X为27例,SDR为27例)。根据修改后的Ryge标准,在基线、6个月、18个月和24个月评估修复情况。在风干牙齿和去除牙菌斑(如有必要)后,目测牙槽面边缘变色和颜色匹配情况。结果:随访24个月,54个修复体临床表现相近。统计分析显示,在7个修改的Ryge标准中,7个组间的数值没有统计学意义。然而,两组的两个修复体在腔面边缘变色评分中都获得了Bravo评级。研究参与者没有报告任何副作用。结论:两种材料(Ceram•X mono和SDR)的修复效果几乎相同。
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引用次数: 7
Association between Early Childhood Caries and Quality of Life: Early Childhood Oral Health Impact Scale and Pufa Index 早期儿童龋病与生活质量的关系:早期儿童口腔健康影响量表和Pufa指数
IF 1.3 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2019-09-25 DOI: 10.3390/dj7040095
N. Sharna, M. Ramakrishnan, Victor A Samuel, Dhanalakshmi Ravikumar, Khangembam Cheenglembi, S. Anil
Early Childhood Caries (ECC) are one of the major oral diseases affecting children. ECC adversely affects the children’s as well as their parent/caregivers quality of life. The present study aims to assess the quality of life in children with Early Childhood Caries aged 6–72 months using the Early Childhood Oral Health Impact Scale. It also aims to compare the quality of life between children with pufa scores of > 0 and a pufa score = 0. A total of 238 children aged 6 months to 72 months with ECC and their parent/caregiver were included in the present study. Oral examinations of the children were performed by the principal examiner using the defs and pufa index, which was followed by a personal interview of the 13 items in the Early Childhood Oral Health Impact scale among the 238 parents/caregivers. The results showed that, overall, Early Childhood Caries have a negative impact on children’s quality of life, as assessed by the parent/caregiver. The overall Early Childhood Oral Health Impact scale score ranged from 0–32 (mean ± SD, 14.12 ± 6.72). Children with a pufa score > 0 (mean ± SD, 16.14 ± 6.27, p < 0.001) have significantly lower quality of life than children with pufa score = 0 (mean ± SD, 9.07 ± 4.94, p < 0.001). Early Childhood Caries had a negative impact on the quality of life of children aged 6–72 months. Children with a pufa score of “0” had better oral health-related quality of life than children with a pufa score > 0.
幼儿龋病是影响儿童的主要口腔疾病之一。ECC对儿童及其父母/照顾者的生活质量产生不利影响。本研究旨在使用早期儿童口腔健康影响量表评估6-72月龄早期儿童龋齿的生活质量。它还旨在比较pufa评分为b>和pufa评分为0的儿童的生活质量。本研究共纳入238名6个月至72个月患有ECC的儿童及其父母/照顾者。主要检查人员采用defs和pufa指数对儿童进行口腔检查,随后对238名家长/照顾者进行了儿童早期口腔健康影响量表13项的个人访谈。结果表明,总体而言,根据父母/照顾者的评估,幼儿龋齿对儿童的生活质量有负面影响。总体儿童早期口腔健康影响量表评分范围为0-32(平均值±标准差,14.12±6.72)。pufa评分为>(平均±SD, 16.14±6.27,p < 0.001)的患儿生活质量明显低于pufa评分为0(平均±SD, 9.07±4.94,p < 0.001)的患儿。幼儿龋病对6-72月龄儿童的生活质量有负面影响。pufa评分为“0”的儿童口腔健康相关生活质量优于pufa评分为bb0 0的儿童。
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引用次数: 21
Early Diagnosis on Oral and Potentially Oral Malignant Lesions: A Systematic Review on the VELscope® Fluorescence Method 早期诊断口腔和潜在的口腔恶性病变:VELscope®荧光法的系统回顾
IF 1.3 Q4 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2019-09-01 DOI: 10.3390/dj7030093
M. Cicciu', G. Cervino, L. Fiorillo, C. D’Amico, G. Oteri, G. Troiano, K. Zhurakivska, L. Lo Muzio, A. Herford, S. Crimi, A. Bianchi, D. Di Stasio, R. Rullo, G. Laino, L. Laino
The fluorescence method is an innovative technique used by pathologists for examining body mucosa, and for the abnormalities tissue screening, potentially leading to the earlier discovery of pre-cancer, cancer or other disease processes. The early detection is one of the best mechanisms for enabling treatment success, increasing survival rates and maintaining a high quality of life. The purpose of this review is to evaluate the clinical efficiency of this diagnostic tool applied to the oral cavity (VELscope®). A literature systematic review has been performed. The initial research provided 53 results after applying the inclusion and exclusion criteria, and after a manual screening of the abstracts by the authors, only 25 results were eligible for review. The results and data contained in all the researches, no older than 10 years, were manually evaluated, and provided useful information on this diagnostic method. The VELscope® mean value about sensitivity and specificity resulted of 70.19% and 65.95%, respectively, by results analysis, but despite this some studies disagree about its clinical effectiveness, and this diagnostic method is still much debated in scientific and clinical medical literature. Surely being able to have efficient and effective tools from this point of view could help the clinician in the diagnosis, and also make timelier the pharmacological or surgical therapy, improving the quality of life of the patient, and in some cases guaranteeing a longer survival term.
荧光法是病理学家用于身体粘膜检查和异常组织筛查的一种创新技术,可能导致早期发现癌前、癌或其他疾病过程。早期发现是使治疗成功、提高生存率和维持高生活质量的最佳机制之一。本综述的目的是评估该口腔诊断工具(VELscope®)的临床疗效。进行了文献系统综述。在应用纳入和排除标准后,最初的研究提供了53个结果,在作者对摘要进行人工筛选后,只有25个结果符合审查条件。所有不超过10年的研究结果和数据都进行了人工评估,并为该诊断方法提供了有用的信息。结果分析表明,VELscope®的敏感性平均值为70.19%,特异性平均值为65.95%,但尽管如此,一些研究对其临床疗效存在分歧,该诊断方法在科学和临床医学文献中仍存在争议。当然,从这个角度来看,能够拥有高效和有效的工具可以帮助临床医生进行诊断,也可以使药物或手术治疗更及时,提高患者的生活质量,在某些情况下保证更长的生存期。
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引用次数: 49
期刊
Open Dentistry Journal
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