首页 > 最新文献

Radiography最新文献

英文 中文
Approaches to reduce medical imaging departments’ environmental impact: A scoping review 减少医学影像科室对环境影响的方法:范围审查。
IF 2.5 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-06-01 DOI: 10.1016/j.radi.2024.08.002

Introduction

Global warming stands as a paramount public health issue of our time, and it is fundamental to explore approaches to green medical imaging departments/(MID). This study aims to map the existing actions in the literature that promote sustainable development in MID towards the promotion of environmental impact reduction.

Methods

Following the JBI methodology and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR), this literature search was conducted on MEDLINE, Embase and CINAHL to encompass studies published after 2013. Combinations of keywords and relevant terms related to environmental sustainability, recycling, medical waste, and greening radiology were applied for this review. Three independent reviewers screened abstracts, titles, and eligible full-text. Disagreement was solved through consensus.

Results

38 out of 4630 articles met all inclusion criteria, and four additional articles were identified and added through reference search. A third of the studies included were published after 2022, and most were conducted in developed countries (36/41). Articles focused on computed tomography (9/41), magnetic resonance imaging (6/41), interventional radiology (4/41), conventional radiography (4/41), ultrasound (2/41), mixed modalities (10/41), or not applicable to an imaging modality (6/41). Four principal categories were identified to decrease ecological footprint: energy consumption, waste management, justification and environmental pollution.

Conclusion

To minimise the environmental impact of MIDs raising awareness and promoting education is fundamental. Examinations must be justified adequately, energy consumption must be reduced, and waste management practices need to be implemented. Further studies are required to prioritise the most effective strategies, supporting decision-making among stakeholders.

Implications for practice

Several strategies are already possible to implement to reduce the environmental impact of MIDs and improve the healthcare outcomes for patients.

导言:全球变暖是当代最重要的公共卫生问题,因此探索绿色医学影像科室(MID)的方法至关重要。本研究旨在对文献中现有的促进医学影像科可持续发展的行动进行梳理,以促进减少对环境的影响:方法:按照 JBI 方法和《系统综述和荟萃分析首选报告项目》(Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews,PRISMA-ScR),在 MEDLINE、Embase 和 CINAHL 上进行文献检索,涵盖 2013 年之后发表的研究。本综述采用了与环境可持续性、回收利用、医疗废物和绿色放射学相关的关键词和相关术语组合。三位独立审稿人筛选了摘要、标题和符合要求的全文。结果:4630 篇文章中有 38 篇符合所有要求:在 4630 篇文章中,有 38 篇符合所有纳入标准,另有 4 篇文章通过参考文献搜索被发现并添加进来。三分之一的纳入研究发表于 2022 年之后,大部分研究在发达国家进行(36/41)。文章主要涉及计算机断层扫描(9/41)、磁共振成像(6/41)、介入放射学(4/41)、传统放射学(4/41)、超声(2/41)、混合模式(10/41)或不适用于某种成像模式(6/41)。为减少生态足迹,确定了四个主要类别:能源消耗、废物管理、正当理由和环境污染:结论:要最大限度地减少 MID 对环境的影响,提高认识和促进教育是根本。考试必须有充分的理由,必须减少能源消耗,必须实施废物管理措施。需要开展进一步研究,确定最有效战略的优先次序,支持利益相关者的决策:实践启示:有几种策略已经可以实施,以减少 MID 对环境的影响并改善患者的医疗效果。
{"title":"Approaches to reduce medical imaging departments’ environmental impact: A scoping review","authors":"","doi":"10.1016/j.radi.2024.08.002","DOIUrl":"10.1016/j.radi.2024.08.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Global warming stands as a paramount public health issue of our time, and it is fundamental to explore approaches to green medical imaging departments/(MID). This study aims to map the existing actions in the literature that promote sustainable development in MID towards the promotion of environmental impact reduction.</p></div><div><h3>Methods</h3><p>Following the JBI methodology and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR), this literature search was conducted on MEDLINE, Embase and CINAHL to encompass studies published after 2013. Combinations of keywords and relevant terms related to environmental sustainability, recycling, medical waste, and greening radiology were applied for this review. Three independent reviewers screened abstracts, titles, and eligible full-text. Disagreement was solved through consensus.</p></div><div><h3>Results</h3><p>38 out of 4630 articles met all inclusion criteria, and four additional articles were identified and added through reference search. A third of the studies included were published after 2022, and most were conducted in developed countries (36/41). Articles focused on computed tomography (9/41), magnetic resonance imaging (6/41), interventional radiology (4/41), conventional radiography (4/41), ultrasound (2/41), mixed modalities (10/41), or not applicable to an imaging modality (6/41). Four principal categories were identified to decrease ecological footprint: energy consumption, waste management, justification and environmental pollution.</p></div><div><h3>Conclusion</h3><p>To minimise the environmental impact of MIDs raising awareness and promoting education is fundamental. Examinations must be justified adequately, energy consumption must be reduced, and waste management practices need to be implemented. Further studies are required to prioritise the most effective strategies, supporting decision-making among stakeholders.</p></div><div><h3>Implications for practice</h3><p>Several strategies are already possible to implement to reduce the environmental impact of MIDs and improve the healthcare outcomes for patients.</p></div>","PeriodicalId":47416,"journal":{"name":"Radiography","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1078817424001998/pdfft?md5=2bbbff9170f634c5b833b3ade4e48d9f&pid=1-s2.0-S1078817424001998-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141989130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical decisions-making within diagnostic radiography – A scoping review 放射诊断中的临床决策--范围审查。
IF 2.6 Q1 Health Professions Pub Date : 2024-05-30 DOI: 10.1016/j.radi.2024.05.008
L.F. Diaby , J. Debess , M. Teli

Objectives

To describe and synthesise literature on clinical decision-making within diagnostic radiography, to uncover the important elements, and to identify knowledge gaps for further investigation. The scoping review question was: How do diagnostic radiographers make clinical decisions?

Key findings

Radiographers make clinical decisions before, during and after examinations. The primary source of information radiographers use is the clinical request, however, if they doubt something, they rely on their colleague's points of view rather than evidence-based practice. Many elements must be considered in the clinical decision-making process; however, lack of autonomy, sparse information on the clinical requests, and lack of time affect the process, which can lead to a barrier to effective decision-making.

Conclusion

Clinical decisions are made based on many different elements before, during, and after examinations in combination with different types of knowledge, as well as technical and organisational aspects within radiography clinical practice.

Implication for practice

There is a need to focus on giving more attention to developing the decision-making elements. In addition, there must be more focus on improving intra-professional work between radiographers and radiologists to facilitate radiographers' opportunities to act on their clinical decisions.

目的:描述并综合有关放射诊断临床决策的文献,揭示其中的重要因素,并找出有待进一步研究的知识空白。范围界定审查的问题是:放射诊断技师如何做出临床决策?放射诊断技师如何做出临床决策?放射技师在检查前、检查中和检查后都会做出临床决策。放射技师使用的主要信息来源是临床要求,但是,如果他们对某些事情有疑问,他们会依赖同事的观点,而不是循证实践。在临床决策过程中必须考虑许多因素;然而,缺乏自主权、临床要求的信息稀少以及缺乏时间都会影响决策过程,从而导致有效决策的障碍:临床决策是基于检查前、检查中和检查后的许多不同因素,结合不同类型的知识,以及放射学临床实践中的技术和组织方面:对实践的启示:需要更加关注决策要素的发展。此外,还必须更加注重改善放射技师和放射医师之间的专业内部工作,以促进放射技师有机会根据自己的临床决定采取行动。
{"title":"Clinical decisions-making within diagnostic radiography – A scoping review","authors":"L.F. Diaby ,&nbsp;J. Debess ,&nbsp;M. Teli","doi":"10.1016/j.radi.2024.05.008","DOIUrl":"10.1016/j.radi.2024.05.008","url":null,"abstract":"<div><h3>Objectives</h3><p>To describe and synthesise literature on clinical decision-making within diagnostic radiography, to uncover the important elements, and to identify knowledge gaps for further investigation. The scoping review question was: How do diagnostic radiographers make clinical decisions?</p></div><div><h3>Key findings</h3><p>Radiographers make clinical decisions before, during and after examinations. The primary source of information radiographers use is the clinical request, however, if they doubt something, they rely on their colleague's points of view rather than evidence-based practice. Many elements must be considered in the clinical decision-making process; however, lack of autonomy, sparse information on the clinical requests, and lack of time affect the process, which can lead to a barrier to effective decision-making.</p></div><div><h3>Conclusion</h3><p>Clinical decisions are made based on many different elements before, during, and after examinations in combination with different types of knowledge, as well as technical and organisational aspects within radiography clinical practice.</p></div><div><h3>Implication for practice</h3><p>There is a need to focus on giving more attention to developing the decision-making elements. In addition, there must be more focus on improving intra-professional work between radiographers and radiologists to facilitate radiographers' opportunities to act on their clinical decisions.</p></div>","PeriodicalId":47416,"journal":{"name":"Radiography","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1078817424001391/pdfft?md5=1a8c11e73e75134ac83e7c1e7f245f48&pid=1-s2.0-S1078817424001391-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141184669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validation of MRI assessment of foot perfusion for improving treatment of patients with peripheral artery disease 验证核磁共振成像对足部灌注的评估,以改善对外周动脉疾病患者的治疗
IF 2.6 Q1 Health Professions Pub Date : 2024-05-25 DOI: 10.1016/j.radi.2024.05.007
M. Bisgaard , K.C. Houlind , A.D. Blankholm , S. Ringgaard , J. Christensen , H. Precht

Introduction

Information on tissue perfusion in the foot is important when treating patients with chronic limb-threatening ischemia. This study aims to test the reliability of different magnetic resonance sequences when measuring perfusion in the foot.

Methods

Sixteen healthy volunteers had their right foot scanned in a test/retest study with six different magnetic resonance sequences (BOLD, multi-echo gradient echo (mGRE), 2D and 3D pCASL, PASL FAIR, and DWI with intravoxel incoherent motion (IVIM) with quantitative measurements of perfusion. For five sequences, cuff-induced ischemia followed by a hyperactive response was measured. Images of the feet were segmented into angiosomes and perfusion data were extracted from the five angiosomes.

Results

BOLD, PASL FAIR, mGRE, and DWI with IVIM had low mean differences between the first and second scans, while the results of 2D and 3D pCASL had the highest differences. Based on a paired t-test, BOLD, and FAIR were able to distinguish between perfusion and no perfusion in all angiosomes with p-values below 0.01. This was not the case with 2D and 3D pCASL with p-values above 0.05 in all angiosomes. The mGRE could not distinguish between perfusion and no perfusion in the lateral side of the foot.

Conclusion

BOLD, mGRE, pASL FAIR, and DWI with IVIM seem to give more robust results compared to 2D and 3D pCASL. Further studies on patients with peripheral artery disease should explore if the sequences can have clinical relevance when assessing tissue ischemia and results of revascularization.

Implications for practice

This study provides knowledge that could be used to improve the diagnosis of patient with chronic limb-threatening ischemia to explore tissue perfusion.

导言足部组织灌注信息对于治疗慢性肢体缺血患者非常重要。这项研究旨在测试不同磁共振序列在测量足部组织灌注时的可靠性。方法:16 名健康志愿者在一项测试/重测研究中使用六种不同的磁共振序列(BOLD、多回波梯度回波(mGRE)、二维和三维 pCASL、PASL FAIR 和带有体腔内不连贯运动(IVIM)的 DWI)扫描了他们的右足,并对灌注进行了定量测量。在五个序列中,测量了袖带诱导缺血后的高活性反应。结果BOLD、PASL FAIR、mGRE和带IVIM的DWI在第一次扫描和第二次扫描之间的平均差异较小,而二维和三维pCASL的结果差异最大。根据配对 t 检验,BOLD 和 FAIR 能够区分所有血管体的灌注和无灌注,P 值低于 0.01。而二维和三维 pCASL 则不然,其 p 值在所有血管体中都高于 0.05。结论与二维和三维 pCASL 相比,BOLD、mGRE、pASL FAIR 和带 IVIM 的 DWI 似乎能提供更可靠的结果。对外周动脉疾病患者的进一步研究应探讨这些序列在评估组织缺血和血管再通结果时是否具有临床意义。
{"title":"Validation of MRI assessment of foot perfusion for improving treatment of patients with peripheral artery disease","authors":"M. Bisgaard ,&nbsp;K.C. Houlind ,&nbsp;A.D. Blankholm ,&nbsp;S. Ringgaard ,&nbsp;J. Christensen ,&nbsp;H. Precht","doi":"10.1016/j.radi.2024.05.007","DOIUrl":"https://doi.org/10.1016/j.radi.2024.05.007","url":null,"abstract":"<div><h3>Introduction</h3><p>Information on tissue perfusion in the foot is important when treating patients with chronic limb-threatening ischemia. This study aims to test the reliability of different magnetic resonance sequences when measuring perfusion in the foot.</p></div><div><h3>Methods</h3><p>Sixteen healthy volunteers had their right foot scanned in a test/retest study with six different magnetic resonance sequences (BOLD, multi-echo gradient echo (mGRE), 2D and 3D pCASL, PASL FAIR, and DWI with intravoxel incoherent motion (IVIM) with quantitative measurements of perfusion. For five sequences, cuff-induced ischemia followed by a hyperactive response was measured. Images of the feet were segmented into angiosomes and perfusion data were extracted from the five angiosomes.</p></div><div><h3>Results</h3><p>BOLD, PASL FAIR, mGRE, and DWI with IVIM had low mean differences between the first and second scans, while the results of 2D and 3D pCASL had the highest differences. Based on a paired <em>t</em>-test, BOLD, and FAIR were able to distinguish between perfusion and no perfusion in all angiosomes with <em>p</em>-values below 0.01. This was not the case with 2D and 3D pCASL with <em>p</em>-values above 0.05 in all angiosomes. The mGRE could not distinguish between perfusion and no perfusion in the lateral side of the foot.</p></div><div><h3>Conclusion</h3><p>BOLD, mGRE, pASL FAIR, and DWI with IVIM seem to give more robust results compared to 2D and 3D pCASL. Further studies on patients with peripheral artery disease should explore if the sequences can have clinical relevance when assessing tissue ischemia and results of revascularization.</p></div><div><h3>Implications for practice</h3><p>This study provides knowledge that could be used to improve the diagnosis of patient with chronic limb-threatening ischemia to explore tissue perfusion.</p></div>","PeriodicalId":47416,"journal":{"name":"Radiography","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S107881742400138X/pdfft?md5=1d4b97ab1d34cb1e2d13f532fd90c0bd&pid=1-s2.0-S107881742400138X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141095853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of X-ray scatter correction software on abdomen radiography in terms of image quality and radiation dose X 射线散射校正软件对腹部射线摄影图像质量和辐射剂量的影响
IF 2.6 Q1 Health Professions Pub Date : 2024-05-25 DOI: 10.1016/j.radi.2024.05.006
M. Sayed , K.M. Knapp , J. Fulford , C. Heales , S.J. Alqahtani

Introduction

The conventional anti-scatter grid is widely used in X-ray radiography to reduce scattered X-rays, but it increases patient dose. Scatter-correction software offers a dose-reducing alternative by correcting for scattered X-rays without a physical grid. Grids and software correction are necessary to reduce scatter radiation and improve image quality especially for the large body parts. The scatter correction can be beneficial in situations where the use of grid is challenging. The implementation of grids and advanced software correction techniques is imperative to ensure that radiographic images maintain high levels of clarity, contrast, and resolution, and ultimately facilitating more accurate diagnoses. This study compares image quality and radiation dose for abdomen exams using scatter correction software and physical grids.

Methods

An anthropomorphic phantom (abdomen) underwent imaging with varying fat and lean tissue layers and body mass index (BMI) configurations. Imaging parameters included 70 kVp tube voltage, 110 cm SID, and Automatic Exposure Control (AEC) both lateral and central chambers. AP abdomen X-ray projections were acquired with and without an anti-scatter grid, and scatter correction software was applied. Image quality was assessed using contrast to noise ratio (CNR) and signal to noise ratio (SNR) metrics. The tube current mAs was considered an exposure factor that affected radiation dose and was used to compare the VG software and physical grid. Radiation dose was measured using Dose Area Products (DAP). The effective dose was estimated using Monte Carlo simulation-PCXMC software. Paired t-tests were used to investigate the image quality difference between the Gridless and VG software, Gridless and PG, and VG software and PG approaches. For the DAP and effective dose, paired t-test was used to investigate the difference between VG software and PG.

Results

Images acquired with a grid had the highest mean CNR (71.3 ± 32) compared to Gridless (50 ± 33.8) and scatter correction software (59.3 ± 37.9). The mean SNR of the grid images was (82.7.3 ± 38.9), which is 18% higher than the scatter correction software images (70.4 ± 36.7) and 29% higher than in the Gridless images (62.9.3 ± 34). The mean DAP value was reduced by 81% when the scatter correction software was used compared to the grid (mean: 65.4 μGy.m2 and 338.2 μGy.m2, respectively) with a significant difference (p = 0.001). Scatter correction software resulted in a lower effective dose compared to physical grid use, (mean difference± SD = −0.3 ± 0.18 mSv) with a significant difference (P = 0.02).

Conclusion

Scatter correction software reduced the radiation dose required but images employing a grid yielded higher CNR and SNR. However, the radiation dose reduction might affect the image quality to a level that impacts the diagnostic information avail

引言 传统的反散射栅格被广泛应用于 X 射线摄影中,以减少散射 X 射线,但它会增加患者的剂量。散射校正软件通过校正散射 X 射线而无需物理栅格,提供了一种降低剂量的替代方法。网格和软件校正对于减少散射辐射和提高图像质量是必要的,尤其是对于身体大的部位。在难以使用网格的情况下,散射校正是有益的。为了确保放射图像保持高水平的清晰度、对比度和分辨率,并最终促进更准确的诊断,网格和先进软件校正技术的实施势在必行。本研究比较了使用散射校正软件和物理网格进行腹部检查的图像质量和辐射剂量。方法对一个拟人化模型(腹部)进行不同脂肪和瘦肉组织层以及体重指数(BMI)配置的成像。成像参数包括 70 kVp 管电压、110 cm SID 和自动曝光控制 (AEC)。采集 AP 腹部 X 光投影时,可使用或不使用反散射网格,并应用散射校正软件。使用对比度与噪声比(CNR)和信噪比(SNR)指标评估图像质量。显像管电流 mAs 被认为是影响辐射剂量的暴露因子,用于比较 VG 软件和物理栅格。辐射剂量使用剂量面积乘积(DAP)进行测量。有效剂量使用蒙特卡洛模拟(PCXMC)软件估算。采用配对 t 检验来研究无网格和 VG 软件、无网格和 PG 以及 VG 软件和 PG 方法之间的图像质量差异。对于 DAP 和有效剂量,使用配对 t 检验来研究 VG 软件和 PG 之间的差异。结果与无栅格(50 ± 33.8)和散射校正软件(59.3 ± 37.9)相比,使用栅格获取的图像具有最高的平均 CNR(71.3 ± 32)。网格图像的平均 SNR 为(82.7.3 ± 38.9),比散射校正软件图像(70.4 ± 36.7)高 18%,比无网格图像(62.9.3 ± 34)高 29%。使用散点校正软件时,DAP 平均值比网格图像降低了 81%(平均值分别为 65.4 μGy.m2 和 338.2 μGy.m2),差异显著(p = 0.001)。散射校正软件与使用物理网格相比,有效剂量更低(平均差异± SD = -0.3 ± 0.18 mSv),差异显著(P = 0.02)。然而,辐射剂量的减少可能会影响图像质量,从而影响可用的诊断信息。对实践的启示总体而言,在无法使用栅格的情况下,X 射线散射校正软件可能会大有可为。
{"title":"The impact of X-ray scatter correction software on abdomen radiography in terms of image quality and radiation dose","authors":"M. Sayed ,&nbsp;K.M. Knapp ,&nbsp;J. Fulford ,&nbsp;C. Heales ,&nbsp;S.J. Alqahtani","doi":"10.1016/j.radi.2024.05.006","DOIUrl":"https://doi.org/10.1016/j.radi.2024.05.006","url":null,"abstract":"<div><h3>Introduction</h3><p>The conventional anti-scatter grid is widely used in X-ray radiography to reduce scattered X-rays, but it increases patient dose. Scatter-correction software offers a dose-reducing alternative by correcting for scattered X-rays without a physical grid. Grids and software correction are necessary to reduce scatter radiation and improve image quality especially for the large body parts. The scatter correction can be beneficial in situations where the use of grid is challenging. The implementation of grids and advanced software correction techniques is imperative to ensure that radiographic images maintain high levels of clarity, contrast, and resolution, and ultimately facilitating more accurate diagnoses. This study compares image quality and radiation dose for abdomen exams using scatter correction software and physical grids.</p></div><div><h3>Methods</h3><p>An anthropomorphic phantom (abdomen) underwent imaging with varying fat and lean tissue layers and body mass index (BMI) configurations. Imaging parameters included 70 kVp tube voltage, 110 cm SID, and Automatic Exposure Control (AEC) both lateral and central chambers. AP abdomen X-ray projections were acquired with and without an anti-scatter grid, and scatter correction software was applied. Image quality was assessed using contrast to noise ratio (CNR) and signal to noise ratio (SNR) metrics. The tube current mAs was considered an exposure factor that affected radiation dose and was used to compare the VG software and physical grid. Radiation dose was measured using Dose Area Products (DAP). The effective dose was estimated using Monte Carlo simulation-PCXMC software. Paired t-tests were used to investigate the image quality difference between the Gridless and VG software, Gridless and PG, and VG software and PG approaches. For the DAP and effective dose, paired t-test was used to investigate the difference between VG software and PG.</p></div><div><h3>Results</h3><p>Images acquired with a grid had the highest mean CNR (71.3 ± 32) compared to Gridless (50 ± 33.8) and scatter correction software (59.3 ± 37.9). The mean SNR of the grid images was (82.7.3 ± 38.9), which is 18% higher than the scatter correction software images (70.4 ± 36.7) and 29% higher than in the Gridless images (62.9.3 ± 34). The mean DAP value was reduced by 81% when the scatter correction software was used compared to the grid (mean: 65.4 μGy.m<sup>2</sup> and 338.2 μGy.m<sup>2</sup>, respectively) with a significant difference (p = 0.001). Scatter correction software resulted in a lower effective dose compared to physical grid use, (mean difference± SD = −0.3 ± 0.18 mSv) with a significant difference (P = 0.02).</p></div><div><h3>Conclusion</h3><p>Scatter correction software reduced the radiation dose required but images employing a grid yielded higher CNR and SNR. However, the radiation dose reduction might affect the image quality to a level that impacts the diagnostic information avail","PeriodicalId":47416,"journal":{"name":"Radiography","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141097694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Challenges confronting sustainability in nuclear medicine practice 核医学实践可持续性面临的挑战
IF 2.6 Q1 Health Professions Pub Date : 2024-05-25 DOI: 10.1016/j.radi.2024.04.026
G.M. Currie , K.E. Hawk , E.M. Rohren

Background

Sustainability can be defined as the state in which consumption or depletion do not exceed regeneration. It can further be considered in five dimensions: environmental, economic, social, human resources, and ecological.

Key findings

There are a number of key issues that threaten sustainability across nuclear medicine clinical and research practices, and across the five dimensions of sustainability there is a requirement for compromise between conflicting priorities. Nonetheless, the field of nuclear medicine benefits from an inherent culture of innovation and forethought which fosters adaptation in order to achieve sustainability.

Conclusion

The principles of sustainability are particularly challenging to navigate due to resource scarcity in nuclear medicine associated with both workforce shortages and supply disruptions. Specific challenges and adaptations are outlined for each of the five dimensions of sustainability.

Implications for practice

There are opportunities for improving sustainability of nuclear medicine practice although success is reliant on a deeper understanding of the interplay across the five dimensions of sustainability.

背景可持续性可定义为消耗或耗竭不超过再生的状态。主要发现有许多关键问题威胁着核医学临床和研究实践的可持续性,在可持续性的五个方面,需要在相互冲突的优先事项之间做出妥协。然而,核医学领域得益于其固有的创新和深谋远虑的文化,这种文化促进了为实现可持续发展而进行的适应性调整。对实践的启示提高核医学实践的可持续性是有机会的,但成功与否取决于对可持续性五个方面相互作用的深入理解。
{"title":"Challenges confronting sustainability in nuclear medicine practice","authors":"G.M. Currie ,&nbsp;K.E. Hawk ,&nbsp;E.M. Rohren","doi":"10.1016/j.radi.2024.04.026","DOIUrl":"https://doi.org/10.1016/j.radi.2024.04.026","url":null,"abstract":"<div><h3>Background</h3><p>Sustainability can be defined as the state in which consumption or depletion do not exceed regeneration. It can further be considered in five dimensions: environmental, economic, social, human resources, and ecological.</p></div><div><h3>Key findings</h3><p>There are a number of key issues that threaten sustainability across nuclear medicine clinical and research practices, and across the five dimensions of sustainability there is a requirement for compromise between conflicting priorities. Nonetheless, the field of nuclear medicine benefits from an inherent culture of innovation and forethought which fosters adaptation in order to achieve sustainability.</p></div><div><h3>Conclusion</h3><p>The principles of sustainability are particularly challenging to navigate due to resource scarcity in nuclear medicine associated with both workforce shortages and supply disruptions. Specific challenges and adaptations are outlined for each of the five dimensions of sustainability.</p></div><div><h3>Implications for practice</h3><p>There are opportunities for improving sustainability of nuclear medicine practice although success is reliant on a deeper understanding of the interplay across the five dimensions of sustainability.</p></div>","PeriodicalId":47416,"journal":{"name":"Radiography","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1078817424001044/pdfft?md5=59197081cb12d52dea70c0994ede1478&pid=1-s2.0-S1078817424001044-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141097767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing safety culture in radiology: Key practices and recommendations for sustainable excellence 加强放射科的安全文化:可持续卓越的主要做法和建议
IF 2.6 Q1 Health Professions Pub Date : 2024-05-25 DOI: 10.1016/j.radi.2024.04.025
M. Chau

Objectives

This review aims to explore and thematically synthesize the existing literature on safety culture within the context of radiology. The primary objective is to identify key practices that effectively strengthen safety culture, highlighting the pivotal roles of leadership, effective teamwork, and interprofessional collaboration in these efforts. The review intends to showcase actionable recommendations that are particularly relevant to the radiology setting.

Key findings

The study highlights that effective leadership is fundamental in establishing and nurturing a safety-first approach within radiology departments. Key practices for promoting a safety culture include safety huddles, leadership walkarounds, quality learning boards, intentional patient rounding (frequent patient-care provider interactions), morbidity and mortality meetings, and multidisciplinary team rounds. These practices have been found to facilitate open communication and transparency, which are crucial elements in creating a sustainable safety culture. Additionally, the study underscores the significant role of radiology managers in driving these safety initiatives and acting as facilitators for a culture of safety, focused on long-term excellence and continuous improvement.

Conclusion

The study concludes that a multifaceted and comprehensive approach is vital for fostering a safety culture in radiology departments, with a focus on sustainable excellence in patient care. The leadership role is critical in this process, with radiology managers being instrumental in implementing and maintaining effective safety practices.

Implications for practice

This study provides best practices for sustainable safety culture in radiology departments. It advocates for healthcare managers to adopt and integrate these identified practices into their operational strategies. Continuous professional development, focusing on safety and quality in patient care, and fostering a collaborative environment for open discussion and learning from safety incidents are essential for the continued advancement and excellence of healthcare services.

目的 本综述旨在探讨放射科安全文化方面的现有文献,并对其进行专题综合。主要目的是确定有效加强安全文化的关键做法,强调领导力、有效的团队合作和专业间协作在这些工作中的关键作用。研究强调,有效的领导力是在放射科建立和培养安全第一方法的基础。促进安全文化的主要做法包括安全会议、领导层巡视、质量学习委员会、有意识的患者查房(患者与医疗服务提供者之间的频繁互动)、发病率和死亡率会议以及多学科团队查房。研究发现,这些做法有助于促进公开交流和透明度,而这正是创建可持续安全文化的关键因素。此外,这项研究还强调了放射科管理人员在推动这些安全措施和促进安全文化方面的重要作用,他们的工作重点是长期卓越和持续改进。在这一过程中,领导者的作用至关重要,放射科管理人员在实施和维护有效的安全实践方面发挥着重要作用。它倡导医疗管理人员采用这些已确定的实践方法,并将其融入到自己的运营策略中。持续的职业发展、关注患者护理的安全和质量、营造公开讨论和从安全事故中学习的合作环境,对于医疗服务的持续进步和卓越发展至关重要。
{"title":"Enhancing safety culture in radiology: Key practices and recommendations for sustainable excellence","authors":"M. Chau","doi":"10.1016/j.radi.2024.04.025","DOIUrl":"https://doi.org/10.1016/j.radi.2024.04.025","url":null,"abstract":"<div><h3>Objectives</h3><p>This review aims to explore and thematically synthesize the existing literature on safety culture within the context of radiology. The primary objective is to identify key practices that effectively strengthen safety culture, highlighting the pivotal roles of leadership, effective teamwork, and interprofessional collaboration in these efforts. The review intends to showcase actionable recommendations that are particularly relevant to the radiology setting.</p></div><div><h3>Key findings</h3><p>The study highlights that effective leadership is fundamental in establishing and nurturing a safety-first approach within radiology departments. Key practices for promoting a safety culture include safety huddles, leadership walkarounds, quality learning boards, intentional patient rounding (frequent patient-care provider interactions), morbidity and mortality meetings, and multidisciplinary team rounds. These practices have been found to facilitate open communication and transparency, which are crucial elements in creating a sustainable safety culture. Additionally, the study underscores the significant role of radiology managers in driving these safety initiatives and acting as facilitators for a culture of safety, focused on long-term excellence and continuous improvement.</p></div><div><h3>Conclusion</h3><p>The study concludes that a multifaceted and comprehensive approach is vital for fostering a safety culture in radiology departments, with a focus on sustainable excellence in patient care. The leadership role is critical in this process, with radiology managers being instrumental in implementing and maintaining effective safety practices.</p></div><div><h3>Implications for practice</h3><p>This study provides best practices for sustainable safety culture in radiology departments. It advocates for healthcare managers to adopt and integrate these identified practices into their operational strategies. Continuous professional development, focusing on safety and quality in patient care, and fostering a collaborative environment for open discussion and learning from safety incidents are essential for the continued advancement and excellence of healthcare services.</p></div>","PeriodicalId":47416,"journal":{"name":"Radiography","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1078817424001032/pdfft?md5=04bbd6279ab27071f303c99ac1fed9ca&pid=1-s2.0-S1078817424001032-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141097768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Nordic survey on artificial intelligence in the radiography profession – Is the profession ready for a culture change? 北欧放射学专业人工智能调查--放射学专业准备好进行文化变革了吗?
IF 2.6 Q1 Health Professions Pub Date : 2024-05-22 DOI: 10.1016/j.radi.2024.04.020
M.R.V. Pedersen , M.W. Kusk , S. Lysdahlgaard , H. Mork-Knudsen , C. Malamateniou , J. Jensen

Introduction

The impact of artificial intelligence (AI) on the radiography profession remains uncertain. Although AI has been increasingly used in clinical radiography, the perspectives of the radiography professionals in Nordic countries have yet to be examined. The primary aim was to examine views of Nordic radiographers ‘on AI, with focus on perspectives, engagement, and knowledge of AI.

Methods

Radiographers from Denmark, Norway, Sweden, Iceland, Greenland, and the Faroe Island were invited through social media platforms to participate in an online survey from March to June 2023. The survey encompassed 29-items and included 4 sections a) demographics, b) barriers and enablers on AI, c) perspectives and experiences of AI and d) knowledge of AI in radiography. Edgars Schein's model of organizational culture was employed to analyse Nordic radiographers' perspectives on AI.

Results

Overall, a total of 421 respondents participated in the survey. A majority were positive/somewhat positive towards AI in radiography e.g., 77.9 % (n = 342) thought that AI would have a positive effect on the profession, and 26% thought that AI would reduce the administrative workload. Most radiographers agreed or strongly agreed that clinicians may have access to AI generated reports (76.8 %, n = 297). Nevertheless, a total of 86 (20.1%) agree or somewhat agreed that AI a potential risk for radiography.

Conclusion

Nordic radiographers are generally positive towards AI, yet uncertainties regarding its implementation persist. The findings underscore the importance of understanding these challenges for the responsible integration of AI systems. Carefully weighing the expected influence of AI against key incentives will support a seamless integration of AI for the benefit not just of the patients, but also of the radiography profession.

Implications for practice

Understanding incentives factors and barriers can help address uncertainties during implementation of AI in clinical practice.

导言人工智能(AI)对放射学专业的影响仍不确定。虽然人工智能已越来越多地应用于临床放射学,但北欧国家放射学专业人员的观点仍有待研究。该研究的主要目的是考察北欧放射技师对人工智能的看法,重点关注他们对人工智能的观点、参与度和知识。方法通过社交媒体平台邀请丹麦、挪威、瑞典、冰岛、格陵兰岛和法罗群岛的放射技师参与 2023 年 3 月至 6 月的在线调查。调查包含 29 个项目,包括 4 个部分:a) 人口统计学;b) 人工智能的障碍和推动因素;c) 人工智能的观点和经验;d) 放射学中的人工智能知识。Edgars Schein 的组织文化模型被用来分析北欧放射技师对人工智能的看法。大多数人对人工智能在放射学中的应用持积极或略带积极的态度,例如,77.9%(n = 342)的人认为人工智能将对该行业产生积极影响,26%的人认为人工智能将减少行政工作量。大多数放射技师同意或非常同意临床医生可以获取人工智能生成的报告(76.8%,n = 297)。然而,共有 86 人(20.1%)同意或基本同意人工智能对放射学构成潜在风险。研究结果强调了了解这些挑战对于负责任地整合人工智能系统的重要性。仔细权衡人工智能的预期影响与关键激励因素,将有助于人工智能的无缝整合,这不仅有利于患者,也有利于放射学专业。
{"title":"A Nordic survey on artificial intelligence in the radiography profession – Is the profession ready for a culture change?","authors":"M.R.V. Pedersen ,&nbsp;M.W. Kusk ,&nbsp;S. Lysdahlgaard ,&nbsp;H. Mork-Knudsen ,&nbsp;C. Malamateniou ,&nbsp;J. Jensen","doi":"10.1016/j.radi.2024.04.020","DOIUrl":"https://doi.org/10.1016/j.radi.2024.04.020","url":null,"abstract":"<div><h3>Introduction</h3><p>The impact of artificial intelligence (AI) on the radiography profession remains uncertain. Although AI has been increasingly used in clinical radiography, the perspectives of the radiography professionals in Nordic countries have yet to be examined. The primary aim was to examine views of Nordic radiographers ‘on AI, with focus on perspectives, engagement, and knowledge of AI.</p></div><div><h3>Methods</h3><p>Radiographers from Denmark, Norway, Sweden, Iceland, Greenland, and the Faroe Island were invited through social media platforms to participate in an online survey from March to June 2023. The survey encompassed 29-items and included 4 sections a) demographics, b) barriers and enablers on AI, c) perspectives and experiences of AI and d) knowledge of AI in radiography. Edgars Schein's model of organizational culture was employed to analyse Nordic radiographers' perspectives on AI.</p></div><div><h3>Results</h3><p>Overall, a total of 421 respondents participated in the survey. A majority were positive/somewhat positive towards AI in radiography e.g., 77.9 % (n = 342) thought that AI would have a positive effect on the profession, and 26% thought that AI would reduce the administrative workload. Most radiographers agreed or strongly agreed that clinicians may have access to AI generated reports (76.8 %, n = 297). Nevertheless, a total of 86 (20.1%) agree or somewhat agreed that AI a potential risk for radiography.</p></div><div><h3>Conclusion</h3><p>Nordic radiographers are generally positive towards AI, yet uncertainties regarding its implementation persist. The findings underscore the importance of understanding these challenges for the responsible integration of AI systems. Carefully weighing the expected influence of AI against key incentives will support a seamless integration of AI for the benefit not just of the patients, but also of the radiography profession.</p></div><div><h3>Implications for practice</h3><p>Understanding incentives factors and barriers can help address uncertainties during implementation of AI in clinical practice.</p></div>","PeriodicalId":47416,"journal":{"name":"Radiography","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S107881742400097X/pdfft?md5=4281273947ebe572f34f0f474e7c152e&pid=1-s2.0-S107881742400097X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141084352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiographers' insights on the impact of their potential role in image interpretation within a low resource setting 放射技师对其在低资源环境下图像解读潜在作用的影响的见解
IF 2.6 Q1 Health Professions Pub Date : 2024-05-21 DOI: 10.1016/j.radi.2024.05.004
A. Karera, T. Musili, L. Kalondo

Introduction

The global shortage of radiologists has led to a growing concern in medical imaging, prompting the exploration of strategies, such as including radiographers in image interpretation, to mitigate this challenge. However, in low-resource settings, progress in adopting similar approaches has been limited. This study aimed to explore radiographers' perceptions regarding the impact of their potential role in image interpretation within a low-resource setting.

Methods

The study used a qualitative descriptive design and was conducted at two public referral hospitals. Radiographers with at least one year of experience were purposively sampled and interviewed using a semi-structured interview guide after consenting. Data saturation determined the sample size, and content analysis was applied for data analysis.

Results

Two themes emerged from fourteen interviews conducted with two male and twelve female radiographers. Theme one revealed the potential for enhanced healthcare delivery through improved diagnostic support, bridging radiologist shortages, career development and fulfilment as positive outcomes of role extension. Theme two revealed possible implementation hurdles including radiographer resistance and reluctance, limited training, lack of professional trust, and legal and ethical challenges.

Conclusion

Radiographers perceived their potential participation positively, envisioning enhanced healthcare delivery, however, possible challenges like resistance and reluctance of radiographers, limited training, and legal/ethical issues pose hurdles. Addressing these challenges through tailored interventions, including formal education could facilitate successful implementation. Further studies are recommended to explore radiographers' competencies, providing empirical evidence for sustaining and expanding this role extension.

Implication for practice

The study further supports the integration of radiographers into image interpretation with the potential to enhance healthcare delivery, however, implementation challenges in low-resource settings require careful consideration.

导言:全球放射科医生的短缺已导致医学影像领域日益严重的问题,促使人们探索各种策略,例如让放射技师参与图像解读,以缓解这一挑战。然而,在低资源环境中,采用类似方法的进展有限。本研究旨在探讨放射技师对其在低资源环境中可能扮演的图像解读角色所产生的影响的看法。研究有目的性地抽取了至少有一年工作经验的放射技师,在征得同意后使用半结构化访谈指南对他们进行了访谈。数据饱和度决定了样本量,数据分析采用了内容分析法。结果在对两名男性和十二名女性放射技师进行的十四次访谈中,出现了两个主题。主题一揭示了通过改善诊断支持、弥补放射科医生短缺、职业发展和成就感来提高医疗服务质量的潜力,这些都是角色延伸的积极成果。主题二揭示了可能存在的实施障碍,包括放射技师的抵触情绪和不情愿、有限的培训、缺乏专业信任以及法律和伦理挑战。通过量身定制的干预措施(包括正规教育)来应对这些挑战,可促进成功实施。建议进一步研究放射技师的能力,为维持和扩大这种角色延伸提供实证证据。对实践的启示该研究进一步支持将放射技师纳入图像解读工作,这有可能提高医疗服务的质量,但需要仔细考虑在低资源环境中实施的挑战。
{"title":"Radiographers' insights on the impact of their potential role in image interpretation within a low resource setting","authors":"A. Karera,&nbsp;T. Musili,&nbsp;L. Kalondo","doi":"10.1016/j.radi.2024.05.004","DOIUrl":"https://doi.org/10.1016/j.radi.2024.05.004","url":null,"abstract":"<div><h3>Introduction</h3><p>The global shortage of radiologists has led to a growing concern in medical imaging, prompting the exploration of strategies, such as including radiographers in image interpretation, to mitigate this challenge. However, in low-resource settings, progress in adopting similar approaches has been limited. This study aimed to explore radiographers' perceptions regarding the impact of their potential role in image interpretation within a low-resource setting.</p></div><div><h3>Methods</h3><p>The study used a qualitative descriptive design and was conducted at two public referral hospitals. Radiographers with at least one year of experience were purposively sampled and interviewed using a semi-structured interview guide after consenting. Data saturation determined the sample size, and content analysis was applied for data analysis.</p></div><div><h3>Results</h3><p>Two themes emerged from fourteen interviews conducted with two male and twelve female radiographers. Theme one revealed the potential for enhanced healthcare delivery through improved diagnostic support, bridging radiologist shortages, career development and fulfilment as positive outcomes of role extension. Theme two revealed possible implementation hurdles including radiographer resistance and reluctance, limited training, lack of professional trust, and legal and ethical challenges.</p></div><div><h3>Conclusion</h3><p>Radiographers perceived their potential participation positively, envisioning enhanced healthcare delivery, however, possible challenges like resistance and reluctance of radiographers, limited training, and legal/ethical issues pose hurdles. Addressing these challenges through tailored interventions, including formal education could facilitate successful implementation. Further studies are recommended to explore radiographers' competencies, providing empirical evidence for sustaining and expanding this role extension.</p></div><div><h3>Implication for practice</h3><p>The study further supports the integration of radiographers into image interpretation with the potential to enhance healthcare delivery, however, implementation challenges in low-resource settings require careful consideration.</p></div>","PeriodicalId":47416,"journal":{"name":"Radiography","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141073282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Within-participants reliability and measurement error of magnetization transfer imaging determinations within the healthy cervical spinal cord 健康颈脊髓内磁化传递成像测定的参与者内部可靠性和测量误差
IF 2.6 Q1 Health Professions Pub Date : 2024-05-20 DOI: 10.1016/j.radi.2024.04.027
H. Al-shaari , C.J. Heales , J. Fulford

Purpose

To assess the within-participant reliability and measurement error in the determination of MTR in the healthy human cervical spinal cord.

Methods and materials

A total of twenty healthy controls (10 male, mean ± sd age: 33.9 ± 3.5 years, 10 females, mean ± sd age: 47.5 ± 14.4 years), with no family history of any neurological disorders or a contraindication to MRI scanning were recruited over a period of two months. Each participant was scanned twice with a 3T MRI scanner using standard MTI sequences. Spinal Cord Toolbox (v5.4) was used for image post-processing. Data were first segmented and then registered to a template and then MTR was computed. The within-participant coefficients of variation (CV%), single and average within-participants intraclass correlation coefficients (ICC) and Bland–Altman plots were determined for MT values over the volume between the 2nd and 5th cervical vertebrae for the total WM and for specific WM regions: dorsal column (DC), ventral column (VC) and lateral column (LC).

Results

MTR showed poor to excellent within-participant reliability for the total WM, DC, VC and LC with single/average ICC values of 0.03/0.06, 0.10/0.18, 0.39/0.75, and 0.001/0.002, respectively, and the CV% reported an acceptable variation with values less than 10%. The Bland–Altman plots showed good within-participant agreement between the scan-rescan values.

Conclusion

This study demonstrates that clinical trials using MTI technique are feasible and shows that quantitative MTI can monitor tissue changes in degenerative WM patients.

Implications for practice

MTI with its MTR index provide broad assessment of the integrity of white matter tissue and are being studied widely in brain as a diagnostic tool for the assessment of different neurological diseases.

方法和材料共招募了 20 名健康对照者(10 名男性,平均年龄(±sd):33.9±3.5 岁;10 名女性,平均年龄(±sd):47.5±14.4 岁),他们均无任何神经系统疾病家族史或核磁共振成像扫描禁忌症,为期两个月。每位受试者使用标准 MTI 序列在 3T 核磁共振成像扫描仪上扫描两次。脊髓工具箱(v5.4)用于图像后处理。首先对数据进行分割,然后将其注册到模板上,然后计算 MTR。对整个 WM 和特定 WM 区域(背侧柱 (DC)、腹侧柱 (VC) 和侧柱 (LC))的第 2 至第 5 颈椎之间体积的 MT 值确定了参与者内变异系数 (CV%)、单个和平均参与者类内相关系数 (ICC) 和 Bland-Altman 图。结果MTR显示,总WM、DC、VC和LC的参与者内部可靠性从差到优,单个/平均ICC值分别为0.03/0.06、0.10/0.18、0.39/0.75和0.001/0.002,CV%报告的变异值小于10%,可以接受。结论这项研究表明,使用 MTI 技术进行临床试验是可行的,并表明定量 MTI 可以监测退行性 WM 患者的组织变化。
{"title":"Within-participants reliability and measurement error of magnetization transfer imaging determinations within the healthy cervical spinal cord","authors":"H. Al-shaari ,&nbsp;C.J. Heales ,&nbsp;J. Fulford","doi":"10.1016/j.radi.2024.04.027","DOIUrl":"https://doi.org/10.1016/j.radi.2024.04.027","url":null,"abstract":"<div><h3>Purpose</h3><p>To assess the within-participant reliability and measurement error in the determination of MTR in the healthy human cervical spinal cord.</p></div><div><h3>Methods and materials</h3><p>A total of twenty healthy controls (10 male, mean ± sd age: 33.9 ± 3.5 years, 10 females, mean ± sd age: 47.5 ± 14.4 years), with no family history of any neurological disorders or a contraindication to MRI scanning were recruited over a period of two months. Each participant was scanned twice with a 3T MRI scanner using standard MTI sequences. Spinal Cord Toolbox (v5.4) was used for image post-processing. Data were first segmented and then registered to a template and then MTR was computed. The within-participant coefficients of variation (CV%), single and average within-participants intraclass correlation coefficients (ICC) and Bland–Altman plots were determined for MT values over the volume between the 2nd and 5th cervical vertebrae for the total WM and for specific WM regions: dorsal column (DC), ventral column (VC) and lateral column (LC).</p></div><div><h3>Results</h3><p>MTR showed poor to excellent within-participant reliability for the total WM, DC, VC and LC with single/average ICC values of 0.03/0.06, 0.10/0.18, 0.39/0.75, and 0.001/0.002, respectively, and the CV% reported an acceptable variation with values less than 10%. The Bland–Altman plots showed good within-participant agreement between the scan-rescan values.</p></div><div><h3>Conclusion</h3><p>This study demonstrates that clinical trials using MTI technique are feasible and shows that quantitative MTI can monitor tissue changes in degenerative WM patients.</p></div><div><h3>Implications for practice</h3><p>MTI with its MTR index provide broad assessment of the integrity of white matter tissue and are being studied widely in brain as a diagnostic tool for the assessment of different neurological diseases.</p></div>","PeriodicalId":47416,"journal":{"name":"Radiography","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1078817424001056/pdfft?md5=9be60c292b80b94d2223dd6c511bb548&pid=1-s2.0-S1078817424001056-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141067829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stability testing of iomeprol and iopamidol formulations subjected to X-ray radiation 接受 X 射线辐射的碘美醇和碘帕米多制剂的稳定性测试
IF 2.6 Q1 Health Professions Pub Date : 2024-05-20 DOI: 10.1016/j.radi.2024.05.003
S. Colombo Serra , A. Fringuello Mingo , C. Incardona , A. Bergantin , E. Vurro , E. Bruno , F. Tedoldi

Introduction

Exposure of iodinated contrast media (ICM) to X-rays is not uncommon, as contrast media are often stored in close proximity to radiological equipment. However, the interaction between X-rays and ICM is not widely investigated in literature. The present study aims to investigate the chemical stability of iomeprol and iopamidol, two commercial iodinated ICM commonly used in diagnostic imaging, under X-rays exposure.

Methods

Different formulations of iopamidol and iomeprol (iodine concentration 9 to 400 mgI/mL, volume 50–500 mL) were exposed to three different conditions of X-ray irradiation: i) 1 month storage in CT room (≈5–15 mGy); (ii) low-dose protocol (≈10 mGy); (ii) stressed protocol (≈100 mGy). Unexposed and exposed solutions were characterized by high-performance liquid chromatography in terms of concentration of active pharmaceutical ingredient (API), iodine species and by products. In addition, appearance and colour of the solutions were inspected and pH measured.

Results

API concentrations, appearance, colour and pH of the exposed formulations remained unaffected by X-rays. Measured concentrations of iodine species and by products were observed well within the acceptability criteria, i.e. values turned out to be lower than specifications limits established by the manufacturer, considering both release and shelf-life values.

Conclusions

Up to 100 mGy X-ray exposure did not induce any alteration of iomeprol and iopamidol formulation, nor a detectable increase in the concentration of iodine species or by-products.

Implications for practice

Our study strengthens the hypothesis that ICM are stable under X-rays exposure up to 100 mGy.

导言碘化造影剂(ICM)暴露于 X 射线的情况并不少见,因为造影剂通常存放在靠近放射设备的地方。然而,文献中对 X 射线与碘化造影剂之间相互作用的研究并不多。本研究旨在调查两种常用于诊断成像的商用碘化 ICM--碘甲萘酚和碘帕米多在 X 射线照射下的化学稳定性。方法将碘帕米多和碘美醇的不同配方(碘浓度为 9 至 400 毫克碘/毫升,体积为 50 至 500 毫升)暴露在三种不同的 X 射线辐照条件下:(i) 在 CT 室中储存 1 个月(≈5 至 15 mGy);(ii) 低剂量方案(≈10 mGy);(ii) 高强度方案(≈100 mGy)。用高效液相色谱法测定未暴露和暴露溶液中的活性药物成分(API)、碘种类和副产品的浓度。此外,还检查了溶液的外观和颜色,并测量了 pH 值。结论高达 100 mGy 的 X 射线照射不会导致碘甲丙醇和碘帕米多制剂发生任何变化,也不会导致碘种类或副产品的浓度出现可检测到的增加。
{"title":"Stability testing of iomeprol and iopamidol formulations subjected to X-ray radiation","authors":"S. Colombo Serra ,&nbsp;A. Fringuello Mingo ,&nbsp;C. Incardona ,&nbsp;A. Bergantin ,&nbsp;E. Vurro ,&nbsp;E. Bruno ,&nbsp;F. Tedoldi","doi":"10.1016/j.radi.2024.05.003","DOIUrl":"https://doi.org/10.1016/j.radi.2024.05.003","url":null,"abstract":"<div><h3>Introduction</h3><p>Exposure of iodinated contrast media (ICM) to X-rays is not uncommon, as contrast media are often stored in close proximity to radiological equipment. However, the interaction between X-rays and ICM is not widely investigated in literature. The present study aims to investigate the chemical stability of iomeprol and iopamidol, two commercial iodinated ICM commonly used in diagnostic imaging, under X-rays exposure.</p></div><div><h3>Methods</h3><p>Different formulations of iopamidol and iomeprol (iodine concentration 9 to 400 mgI/mL, volume 50–500 mL) were exposed to three different conditions of X-ray irradiation: i) 1 month storage in CT room (≈5–15 mGy); (ii) low-dose protocol (≈10 mGy); (ii) stressed protocol (≈100 mGy). Unexposed and exposed solutions were characterized by high-performance liquid chromatography in terms of concentration of active pharmaceutical ingredient (API), iodine species and by products. In addition, appearance and colour of the solutions were inspected and pH measured.</p></div><div><h3>Results</h3><p>API concentrations, appearance, colour and pH of the exposed formulations remained unaffected by X-rays. Measured concentrations of iodine species and by products were observed well within the acceptability criteria, i.e. values turned out to be lower than specifications limits established by the manufacturer, considering both release and shelf-life values.</p></div><div><h3>Conclusions</h3><p>Up to 100 mGy X-ray exposure did not induce any alteration of iomeprol and iopamidol formulation, nor a detectable increase in the concentration of iodine species or by-products.</p></div><div><h3>Implications for practice</h3><p>Our study strengthens the hypothesis that ICM are stable under X-rays exposure up to 100 mGy.</p></div>","PeriodicalId":47416,"journal":{"name":"Radiography","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141067830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Radiography
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1