The Pain PLUS literature surveillance service demonstrates the importance of high-quality literature to support decision-making and practice for the use of opioids. McMaster University has had a significant leadership role in advancing the practice of evidence-based health care. Part of this leadership has been through the creation of programs and services that support individual clinicians and others in their striving to stay up to date in the rapidly expanding volume of healthcare knowledge and to separate high-quality materials from the large quantity of published work in order to make best use of their, often limited, time for review of publications.
疼痛 PLUS 文献监测服务表明，高质量的文献对于支持使用阿片类药物的决策和实践非常重要。麦克马斯特大学在推动循证医疗实践方面发挥了重要的领导作用。这种领导作用的一部分是通过创建各种计划和服务来支持临床医生和其他人员努力跟上快速增长的医疗保健知识的步伐，并将高质量的资料从大量的出版工作中分离出来，以便充分利用他们往往有限的时间来审阅出版物。
{"title":"Safer and more effective use of opioids","authors":"Norm Buckley, Jason Busse","doi":"10.56367/oag-043-11541","DOIUrl":"https://doi.org/10.56367/oag-043-11541","url":null,"abstract":"\u0000 \u0000 The Pain PLUS literature surveillance service demonstrates the importance of high-quality literature to support decision-making and practice for the use of opioids. McMaster University has had a significant leadership role in advancing the practice of evidence-based health care. Part of this leadership has been through the creation of programs and services that support individual clinicians and others in their striving to stay up to date in the rapidly expanding volume of healthcare knowledge and to separate high-quality materials from the large quantity of published work in order to make best use of their, often limited, time for review of publications.\u0000","PeriodicalId":475859,"journal":{"name":"Open Access Government","volume":"44 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141660231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The European Federation of Food Science and Technology (EFFoST) wants to revolutionise the food industry with its new TITAN Project. This four-year Horizon Europe initiative seeks to enhance transparency, improve food safety, and promote sustainability in the agri-food sector. In an interview with Open Access Governments editor Harriet Belderbos, key representatives of the TITAN project shared their insights and objectives.
欧洲食品科技联合会（EFFoST）希望通过其新的 TITAN 项目彻底改变食品工业。这项为期四年的 "地平线欧洲 "计划旨在提高农业食品行业的透明度、改善食品安全并促进可持续发展。在接受 Open Access Government 编辑 Harriet Belderbos 的采访时，TITAN 项目的主要代表分享了他们的见解和目标。
{"title":"The TITAN Project: Transforming the food system for a sustainable future","authors":"Edward Sliwinski","doi":"10.56367/oag-043-11527","DOIUrl":"https://doi.org/10.56367/oag-043-11527","url":null,"abstract":"\u0000 \u0000 The European Federation of Food Science and Technology (EFFoST) wants to revolutionise the food industry with its new TITAN Project. This four-year Horizon Europe initiative seeks to enhance transparency, improve food safety, and promote sustainability in the agri-food sector. In an interview with Open Access Governments editor Harriet Belderbos, key representatives of the TITAN project shared their insights and objectives.\u0000","PeriodicalId":475859,"journal":{"name":"Open Access Government","volume":"21 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141659754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
University President Elmer Guy examines the vital role of educational institutions like Navajo Technical University in empowering communities and supporting their efforts to achieve clean energy development goals. The Navajo Nation encompasses more than 25,000 square miles of desert and scrubland in the southwestern US. The Navajo People, or Diné as they refer to themselves, have long advocated for self-determination. Through the Navajo Technical University (NTU), the Navajo community has the ability to educate its youth in line with its traditions, cultures, and beliefs. However, the lack of Navajo engineering faculty results in a scarcity of role models for engineering students.
{"title":"Promoting clean energy in the Navajo nation","authors":"Peter Romine","doi":"10.56367/oag-043-11532","DOIUrl":"https://doi.org/10.56367/oag-043-11532","url":null,"abstract":"\u0000 \u0000 University President Elmer Guy examines the vital role of educational institutions like Navajo Technical University in empowering communities and supporting their efforts to achieve clean energy development goals. The Navajo Nation encompasses more than 25,000 square miles of desert and scrubland in the southwestern US. The Navajo People, or Diné as they refer to themselves, have long advocated for self-determination. Through the Navajo Technical University (NTU), the Navajo community has the ability to educate its youth in line with its traditions, cultures, and beliefs. However, the lack of Navajo engineering faculty results in a scarcity of role models for engineering students.\u0000","PeriodicalId":475859,"journal":{"name":"Open Access Government","volume":"17 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141661100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Arpita Bose, PhD from Washington University in St. Louis, guides us through host-associated impacts and biotechnological applications of extracellular electron transfer in electrochemically active bacteria. Electron flow and oxidative and reductive reactions, referred to as “redox reactions,” collectively impact the outcomes of biochemical pathways essential for cell growth, energy conservation, and stress response throughout various organisms. An example of these organisms is electrochemically active bacteria (EAB), which can link internal redox reactions with external electron acceptors or donors via a process known as extracellular electron transfer (EET).
{"title":"Extracellular electron transfer explained","authors":"Arpita Bose, Aiden Wang","doi":"10.56367/oag-043-11034","DOIUrl":"https://doi.org/10.56367/oag-043-11034","url":null,"abstract":"\u0000 \u0000 Arpita Bose, PhD from Washington University in St. Louis, guides us through host-associated impacts and biotechnological applications of extracellular electron transfer in electrochemically active bacteria. Electron flow and oxidative and reductive reactions, referred to as “redox reactions,” collectively impact the outcomes of biochemical pathways essential for cell growth, energy conservation, and stress response throughout various organisms. An example of these organisms is electrochemically active bacteria (EAB), which can link internal redox reactions with external electron acceptors or donors via a process known as extracellular electron transfer (EET).\u0000","PeriodicalId":475859,"journal":{"name":"Open Access Government","volume":"52 14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141659950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thomas J. Webster, PhD provides a firsthand account of the obstacles hindering innovation in medicine, covering publishing, conferences, politics, funding, universities, and industry. Innovation is hard. Such a simple word, but so many obstacles exist to innovate and, more importantly, to turn your innovation into a medical product that actually improves human health for ultimate technology validation. As I look back at my almost 25-year career innovating in medicine, I find myself continuously reflecting on how I was able to develop innovative solutions for improving medicine despite constant obstacles. One particular innovation that I am extremely proud of involves my efforts to integrate nanotechnology into orthopedic implants. How did my team and I develop nanotextured orthopedic devices now in over 30,000 patients in which zero implants have failed to date (no infection, no chronic inflammation, and no implant loosening) when the industry average shows orthopedic implant failure rates over 10%, increasing daily (Figure 1)?(1, 2)
托马斯-J.-韦伯斯特（Thomas J. Webster）博士以第一手资料介绍了阻碍医学创新的障碍，内容涉及出版、会议、政治、资金、大学和工业。创新很难。如此简单的一个词，却存在如此多的创新障碍，更重要的是，要将创新转化为真正改善人类健康的医疗产品，以最终实现技术验证。回顾我将近 25 年的医学创新生涯，我发现自己一直在反思，我是如何克服重重障碍，开发出改进医学的创新解决方案的。其中令我深感自豪的一项创新是，我努力将纳米技术融入骨科植入物。目前，我和我的团队开发的纳米纹理骨科植入物已用于 3 万多名患者，迄今为止没有植入物出现故障（无感染、无慢性炎症、无植入物松动），而行业平均骨科植入物故障率超过 10%，且每天都在增加（图 1）。
{"title":"Opinion: What are the barriers to innovation in medicine?","authors":"Thomas J Webster","doi":"10.56367/oag-043-11059","DOIUrl":"https://doi.org/10.56367/oag-043-11059","url":null,"abstract":"\u0000 \u0000 Thomas J. Webster, PhD provides a firsthand account of the obstacles hindering innovation in medicine, covering publishing, conferences, politics, funding, universities, and industry. Innovation is hard. Such a simple word, but so many obstacles exist to innovate and, more importantly, to turn your innovation into a medical product that actually improves human health for ultimate technology validation. As I look back at my almost 25-year career innovating in medicine, I find myself continuously reflecting on how I was able to develop innovative solutions for improving medicine despite constant obstacles. One particular innovation that I am extremely proud of involves my efforts to integrate nanotechnology into orthopedic implants. How did my team and I develop nanotextured orthopedic devices now in over 30,000 patients in which zero implants have failed to date (no infection, no chronic inflammation, and no implant loosening) when the industry average shows orthopedic implant failure rates over 10%, increasing daily (Figure 1)?(1, 2)\u0000","PeriodicalId":475859,"journal":{"name":"Open Access Government","volume":"16 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141662224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Curbs on animal testing mean human tissues derived from induced pluripotent stem cells offer a promising platform in discovering novel treatments for cardiac ailments. In the realm of research and development in novel treatments for cardiac ailments, the use of animal models, such as mice, presents inherent limitations due to physiological discrepancies between species, specifically between humans and experimental animals. For instance, the heart rate in mice can surpass 500 beats per minute, a rate considerably faster than that observed in humans.
{"title":"The role of stem cell-derived tissues in novel treatments for cardiac ailments","authors":"Yoshinori Yoshida","doi":"10.56367/oag-043-11574","DOIUrl":"https://doi.org/10.56367/oag-043-11574","url":null,"abstract":"\u0000 \u0000 Curbs on animal testing mean human tissues derived from induced pluripotent stem cells offer a promising platform in discovering novel treatments for cardiac ailments. In the realm of research and development in novel treatments for cardiac ailments, the use of animal models, such as mice, presents inherent limitations due to physiological discrepancies between species, specifically between humans and experimental animals. For instance, the heart rate in mice can surpass 500 beats per minute, a rate considerably faster than that observed in humans.\u0000","PeriodicalId":475859,"journal":{"name":"Open Access Government","volume":"52 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141660057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Addressing the triple jeopardy of ageism, sexism and racism within healthcare systems is crucial to ensuring equitable health outcomes for all older people, write Professor Jordana Salma, Professor Sherry Dahlke and Professor Kathleen Hunter of the Faculty of Nursing at the University of Alberta. Ageism involves negative thoughts, beliefs and behaviours towards older people, and its effects are felt worldwide, leading to the denial of human rights based on age (World Health Organization, 2021).
{"title":"A call for intersectionality in gerontological nursing education","authors":"Jordana Salma, S. Dahlke, Kathleen F Hunter","doi":"10.56367/oag-043-11272","DOIUrl":"https://doi.org/10.56367/oag-043-11272","url":null,"abstract":"\u0000 \u0000 Addressing the triple jeopardy of ageism, sexism and racism within healthcare systems is crucial to ensuring equitable health outcomes for all older people, write Professor Jordana Salma, Professor Sherry Dahlke and Professor Kathleen Hunter of the Faculty of Nursing at the University of Alberta. Ageism involves negative thoughts, beliefs and behaviours towards older people, and its effects are felt worldwide, leading to the denial of human rights based on age (World Health Organization, 2021).\u0000","PeriodicalId":475859,"journal":{"name":"Open Access Government","volume":"10 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141662393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Professor Pete W. Jacoby, from Washington State University, researches methods to combat impacts of global warming by enhancing soil water retention for vineyard resilience. Drought has long been a serious threat to regions that depend on natural rainfall for crop production. For centuries, irrigation from surface water or wells has been applied to supplement natural rainfall to assure successful crop production, leading to estimates that agriculture accounts for 70% of global water use.
华盛顿州立大学教授 Pete W.华盛顿州立大学的雅各比教授正在研究如何通过提高土壤保水能力来抵御全球变暖的影响，从而增强葡萄园的抗灾能力。长期以来，干旱一直严重威胁着依赖自然降雨进行作物生产的地区。几个世纪以来，人们一直使用地表水或水井灌溉来补充自然降雨，以确保作物的顺利生产，据估计，农业用水占全球用水量的 70%。
{"title":"Combating drought to increase soil water retention in vineyards","authors":"P. W. Jacoby","doi":"10.56367/oag-043-10909","DOIUrl":"https://doi.org/10.56367/oag-043-10909","url":null,"abstract":"\u0000 \u0000 Professor Pete W. Jacoby, from Washington State University, researches methods to combat impacts of global warming by enhancing soil water retention for vineyard resilience. Drought has long been a serious threat to regions that depend on natural rainfall for crop production. For centuries, irrigation from surface water or wells has been applied to supplement natural rainfall to assure successful crop production, leading to estimates that agriculture accounts for 70% of global water use.\u0000","PeriodicalId":475859,"journal":{"name":"Open Access Government","volume":"30 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141660410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vincent Prevot, Markus Schwaninger, Ruben Nogueiras
Dr Vincent Prevot and Professors Markus Schwaninger and Ruben Nogueiras explain the significance of the perinatal maternal lifestyle, specifically prolonged lactation, in shielding offspring from chronic disease. In recent years, the escalating prevalence of obesity and its associated diseases has prompted numerous studies covering broad aspects of metabolism, from the genetic inheritance of disorders to the early emergence of non-genetic metabolic traits. Pregnancy and lactation are now identified as the pivotal periods for establishing these traits, which can develop from infancy into adulthood. Therefore, maternal influences are crucial in the development of pathologies arising from a combination of genetic and non-genetic factors, as well as lifestyle.
Vincent Prevot 博士、Markus Schwaninger 教授和 Ruben Nogueiras 教授解释了围产期母体生活方式（尤其是延长哺乳期）在保护后代免受慢性疾病侵害方面的重要作用。近年来，肥胖症及其相关疾病的发病率不断攀升，促使人们对新陈代谢的各个方面进行了大量研究，从疾病的遗传到非遗传新陈代谢特征的早期出现。妊娠期和哺乳期现在被认为是建立这些特征的关键时期，这些特征可以从婴儿期发展到成年期。因此，在遗传和非遗传因素以及生活方式的共同作用下，母体的影响对病症的形成至关重要。
{"title":"Prolonged lactation: Preventing obesity since infancy","authors":"Vincent Prevot, Markus Schwaninger, Ruben Nogueiras","doi":"10.56367/oag-043-10410","DOIUrl":"https://doi.org/10.56367/oag-043-10410","url":null,"abstract":"\u0000 \u0000 Dr Vincent Prevot and Professors Markus Schwaninger and Ruben Nogueiras explain the significance of the perinatal maternal lifestyle, specifically prolonged lactation, in shielding offspring from chronic disease. In recent years, the escalating prevalence of obesity and its associated diseases has prompted numerous studies covering broad aspects of metabolism, from the genetic inheritance of disorders to the early emergence of non-genetic metabolic traits. Pregnancy and lactation are now identified as the pivotal periods for establishing these traits, which can develop from infancy into adulthood. Therefore, maternal influences are crucial in the development of pathologies arising from a combination of genetic and non-genetic factors, as well as lifestyle.\u0000","PeriodicalId":475859,"journal":{"name":"Open Access Government","volume":"37 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141660477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this Q&A, a team from the RESTART project explores their groundbreaking intervention model designed to empower people to embrace healthier lifestyles as they near retirement. The RESTART Project exemplifies the proactive approach public health initiatives can take to address health risks associated with ageing populations; what else can we learn? The inspiration for RESTART came from the Tromsø Study, an ongoing population study in Tromsø, Norway. The study revealed a concerning trend: a significant rise in overweight and obesity among participants aged 40 and over.
{"title":"RESTART Project Q&A: Empowering healthy aging","authors":"S. Grimsgaard, André Henriksen","doi":"10.56367/oag-043-11581","DOIUrl":"https://doi.org/10.56367/oag-043-11581","url":null,"abstract":"\u0000 \u0000 In this Q&A, a team from the RESTART project explores their groundbreaking intervention model designed to empower people to embrace healthier lifestyles as they near retirement. The RESTART Project exemplifies the proactive approach public health initiatives can take to address health risks associated with ageing populations; what else can we learn? The inspiration for RESTART came from the Tromsø Study, an ongoing population study in Tromsø, Norway. The study revealed a concerning trend: a significant rise in overweight and obesity among participants aged 40 and over.\u0000","PeriodicalId":475859,"journal":{"name":"Open Access Government","volume":"24 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141661949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：