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Sulfonyl radicals generation via β-scission 通过 β 裂解生成砜基自由基
IF 15.7 2区 化学 Q1 Chemistry Pub Date : 2024-02-01 DOI: 10.1016/j.trechm.2024.01.004
Shen Cao, Lu Wang, Xiaoping Chen, Xiaheng Zhang
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引用次数: 0
Sulfonyl radicals generation via β-scission 通过 β 裂解生成砜基自由基
IF 15.7 2区 化学 Q1 Chemistry Pub Date : 2024-02-01 DOI: 10.1016/j.trechm.2024.01.004
Shen Cao, Lu Wang, Xiaoping Chen, Xiaheng Zhang
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引用次数: 0
Amyloid-β-interacting proteins in peripheral fluids of Alzheimer’s disease 阿尔茨海默氏症患者外周体液中的淀粉样蛋白-β-相互作用蛋白
IF 15.7 2区 化学 Q1 Chemistry Pub Date : 2024-02-01 DOI: 10.1016/j.trechm.2024.01.003
Yelim Yi, Jimin Lee, Mi Hee Lim
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引用次数: 0
Asymmetric radical aziridination of alkenes 烯的不对称自由基氮丙啶化反应
IF 15.7 2区 化学 Q1 Chemistry Pub Date : 2024-01-24 DOI: 10.1016/j.trechm.2023.12.003
Wan-Chen Cindy Lee, X. Peter Zhang
Abstract not available
无摘要
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引用次数: 0
Tailoring chemistry for inorganic 3D micro-optics 为无机 3D 微型光学量身定制化学材料
IF 15.7 2区 化学 Q1 Chemistry Pub Date : 2024-01-19 DOI: 10.1016/j.trechm.2023.12.005
J.P. Winczewski, J. Arriaga-Dávila, C. Rosero-Arias, A. Susarrey-Arce

Additive manufacturing of metal oxides possesses immense potential in micro-optics, enabling intricate glass and ceramic structures at the highest definition. However, a limited range of inorganic–organic monomeric precursors restrains its advancements. New inorganic–organic precursors should be developed to unlock optical functionalities to manipulate light in the third dimension.

金属氧化物的快速成型技术在微光学领域具有巨大潜力,可实现最高清晰度的复杂玻璃和陶瓷结构。然而,无机-有机单体前驱体的范围有限,制约了其发展。应开发新的无机-有机前体,以释放光学功能,在三维空间操纵光线。
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引用次数: 0
Harnessing chemical functionality of lignin towards stimuli-responsive materials 利用木质素的化学功能性开发刺激响应材料
IF 15.7 2区 化学 Q1 Chemistry Pub Date : 2024-01-11 DOI: 10.1016/j.trechm.2023.12.001
Yong Zheng, Adrian Moreno, Yiqi Zhang, Mika H. Sipponen, Lin Dai

The mysteries of chemical structures and properties of lignin are gradually being unveiled. In parallel, lignin is gaining ground as a versatile resource for the development of stimuli-responsive materials with environmentally friendly, high-performance, and multifunctional characters. This review focuses on synthesis and mechanisms of lignin-based stimuli-responsive materials, highlighting the chemical structures linked to responses to various different stimuli, such as pH and temperature. We also highlight applications of these materials in drug carriers, bioimaging, shape memory, strain sensors, and substance detection, with the objective to showcase the untapped potential of lignin, challenging the prevailing notion that lignin is merely a by-product of the pulp industry. Finally, we identify challenges and propose future directions for the development of lignin-based stimuli-responsive materials.

木质素化学结构和性质的奥秘正逐渐被揭开。与此同时,木质素作为一种多功能资源,在开发具有环境友好、高性能和多功能特性的刺激响应材料方面也日益受到重视。本综述重点介绍基于木质素的刺激响应材料的合成和机理,重点介绍与对各种不同刺激(如 pH 值和温度)的响应有关的化学结构。我们还重点介绍了这些材料在药物载体、生物成像、形状记忆、应变传感器和物质检测等方面的应用,旨在展示木质素尚未开发的潜力,对 "木质素只是纸浆工业的副产品 "这一普遍观点提出质疑。最后,我们明确了木质素刺激响应材料的发展面临的挑战,并提出了未来的发展方向。
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引用次数: 0
Converting heterotrophic Saccharomyces cerevisiae to a synthetic methylotroph 将异养型酿酒酵母转化为合成甲基营养体
IF 15.7 2区 化学 Q1 Chemistry Pub Date : 2024-01-10 DOI: 10.1016/j.trechm.2023.12.004
Pan Zhu, Ziqi Zhang, Yufei Li

It is challenging to convert a non-methylotrophic yeast to a synthetic methylotroph. In a recently described new method, Nielsen, Keasling, Chen, Bai, and coworkers show that Saccharomyces cerevisiae can be engineered to grow solely on methanol, which potentially emerges as a promising platform for one-carbon (C1)-based biomanufacturing.

将非养甲型酵母转化为合成的养甲型酵母具有挑战性。在最近描述的一种新方法中,Nielsen、Keasling、Chen、Bai 及其同事表明,可以改造酿酒酵母菌,使其只在甲醇中生长,这有可能成为基于一碳(C1)的生物制造的一个前景广阔的平台。
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引用次数: 0
Advisory Board and Contents 咨询委员会和内容
IF 15.7 2区 化学 Q1 Chemistry Pub Date : 2024-01-10 DOI: 10.1016/s2589-5974(23)00272-1
Abstract not available
无摘要
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引用次数: 0
Subscription and Copyright Information 订阅和版权信息
IF 15.7 2区 化学 Q1 Chemistry Pub Date : 2024-01-10 DOI: 10.1016/s2589-5974(23)00275-7
Abstract not available
无摘要
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引用次数: 0
Brewing wellness: sugar-based synthesis of anti-obesity celastrol 酿造健康:以糖为基础合成抗肥胖青霉烯醇
IF 15.7 2区 化学 Q1 Chemistry Pub Date : 2024-01-09 DOI: 10.1016/j.trechm.2023.12.006
Yi Lou, Yifeng Huang, Jiangtao Gao

Addressing the burgeoning global obesity crisis, Zhao et al. recently presented innovative developments in celastrol synthesis, a potent anti-obesity agent. They unified plant biochemistry, metabolic engineering, and chemistry to map an effective celastrol biosynthetic path in yeast. The study emphasizes new opportunities for the commercial production of celastrol, revealing future potential for specialized metabolite production.

为了应对日益严重的全球肥胖危机,Zhao 等人最近介绍了一种有效的抗肥胖药物--青霉酚合成的创新发展。他们将植物生物化学、代谢工程和化学相结合,在酵母中绘制了一条有效的青霉酚生物合成路径。该研究强调了青霉烯醇商业化生产的新机遇,揭示了特殊代谢物生产的未来潜力。
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引用次数: 0
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