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Elder Abuse in the Orthopaedic Patient: An Updated Review of Prevalence, Identification, and Screening Tools for Orthopaedic Surgeons. 骨科患者中的虐待老人行为:骨科外科医生对虐待老人行为的发生率、识别和筛查工具的最新回顾》(An updated Review of Prevalence, Identification, and Screening Tools for Orthopaedic Surgeons.
IF 1.6 4区 医学 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2024-08-16 eCollection Date: 2024-01-01 DOI: 10.1177/21514593241266486
Sophia Scott, Devon T Brameier, Ida Tryggedsson, Nishant Suneja, Derek S Stenquist, Michael J Weaver, Arvind von Keudell

Introduction: Elder abuse is a prevalent, though often overlooked and underreported, cause of musculoskeletal injury in the elderly population. The purpose of this review is to provide an updated overview of the prevalence of elder abuse, its association with musculoskeletal injuries, and the available resources to aid orthopaedic surgeons in early detection and intervention.

Significance: Improved training on this topic is needed throughout the medical education of orthopaedic surgeons to effectively recognize and address elder abuse. Our findings reveal an urgent need for increased awareness, education, and collaboration among healthcare professionals to address this significant public health concern. As the aging population continues to grow, understanding the connection between elder abuse and musculoskeletal injuries is essential for providing comprehensive care to older adults.

Results: This review offers practical recommendations for identifying individuals at risk of elder abuse and outlines strategies for intervention. Indicators of abuse range from obvious signs like dirty clothes, neglect, and unattended injuries from falls, to more subtle cues requiring careful observation and questioning, such as mental health symptoms and family histories of abuse.

Conclusion: By shedding light on this often-overlooked issue, this review advocates for a proactive approach to identifying and addressing elder abuse to safeguard the well-being and quality of life of older individuals.

导言:虐待老人是导致老年人群肌肉骨骼损伤的一个普遍原因,但往往被忽视和报告不足。本综述旨在概述虐待老人行为的普遍性、虐待老人行为与肌肉骨骼损伤之间的关系,以及帮助骨科医生早期发现和干预虐待老人行为的可用资源:意义:需要在骨科医生的整个医学教育过程中加强对这一主题的培训,以有效识别和解决虐待老人问题。我们的研究结果表明,迫切需要提高医护人员的意识、加强教育和合作,以解决这一重大的公共卫生问题。随着老龄化人口的不断增长,了解虐待老人与肌肉骨骼损伤之间的联系对于为老年人提供全面护理至关重要:结果:本综述为识别有虐待老人风险的个人提供了实用建议,并概述了干预策略。虐待的迹象包括明显的迹象,如肮脏的衣服、忽视和无人照看的跌倒伤害,以及需要仔细观察和询问的更微妙的线索,如精神健康症状和家庭虐待史:通过揭示这个经常被忽视的问题,本综述提倡采取积极主动的方法来识别和解决虐待老人问题,以保障老年人的福祉和生活质量。
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引用次数: 0
The Impact of Improved Compliance With Enhanced Recovery After Surgery on Frail Patients Undergoing Multi-Level Posterior Lumbar Fusion Surgery for Degenerative Lumbar Diseases. 对接受多层次后路腰椎融合手术治疗腰椎退行性疾病的体弱患者而言,提高术后恢复的依从性有何影响?
IF 1.6 4区 医学 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2024-08-15 eCollection Date: 2024-01-01 DOI: 10.1177/21514593241273117
Xiaoying Zhang, Xuewei Dong, Huili Luo, Yanli Song, Shengmin Chen

Background: Patients with frailty are more prone to have perioperative adverse events, and enhanced recovery after surgery (ERAS) has been widely adopted to improve perioperative outcomes. The purpose of this study was to assess the impact of improved compliance with ERAS on perioperative outcomes in frail patients.

Methods: Geriatric patients (over 65 years) who underwent multi-level lumbar fusion surgery between June 2017 and June 2022 were included. The patients were divided into two groups according to their degree of compliance with the ERAS. Stepwise nearest-neighbor propensity score matching 1:1 cohorts for age, gender, body mass index (BMI), American Society of Anesthesiologists (ASA) classfication and Charlson Comorbidity Index (CCI) was performed between groups, namely frail-compliant (FC), frail-noncompliant (FN). Further length of stay (LOS), complications and clinical efficacy were compared between groups.

Results: There were 83 pairs of well-balanced patients with comparable clinical baseline data. It was worth noting that patients in FC group has significant lower overall complications (20.5% in the FC group vs 39.8% in the FN group, P = 0.007), major complications (7.2% in the FC group vs 19.3% in the FN group, P = 0.022) and shorter LOS (11.18 ± 5.32 in the FC group vs 14.45 ± 4.68 in the FN group, P < 0.001) than patients in FN group. In addition, the initial occurrence of ambulation (2.14 ± 1.21 in FC group vs 3.18 ± 1.73 in FN group, P = 0.012) and bowel movement (3.68 ± 1.24 in FC group vs 4.17 ± 1.32 in FN group, P = 0.031) were earlier for patients in FC group than patients in FN group. With regard to clinical efficacy, there were no significant difference between FC and FN group in terms of patients who meet minimal clinical important difference (MCID) for Oswestry Disability Index (ODI) at postoperative day (POD) 30, Visual Analog Scale (VAS) for back at POD 30-90 and VAS for legs at POD 30, 90, and 180 follow-up intervals. However, there were significant more patients meeting MCID for ODI at POD 90 and180, and VAS for back at POD 180 between FC and FN group.

Conclusions: In this retrospective cohort study, we found that frail patients with higher ERAS adherence group had a lower incidence of overall complication, mjor complications, and a shorter LOS than their lower ERAS adherence counterparts. In addition, frail patients with higher ERAS adherence had earlier ambulatioin and bowel movement. More importantly, we found there were significant more patients meeting MCID for ODI at POD 90 and180, and VAS for back at POD 180 in higher ERAS adherence than their lower counterparts.

背景:体弱患者更容易发生围手术期不良事件,为改善围手术期预后,增强术后恢复(ERAS)已被广泛采用。本研究的目的是评估提高ERAS依从性对体弱患者围手术期预后的影响:纳入2017年6月至2022年6月期间接受多层次腰椎融合手术的老年患者(65岁以上)。根据患者对ERAS的遵从程度将其分为两组。根据年龄、性别、体重指数(BMI)、美国麻醉医师协会(ASA)分级和夏尔森合并症指数(CCI)进行逐步近邻倾向得分匹配,1:1 组间进行匹配,即体弱遵从组(FC)和体弱不遵从组(FN)。此外,还比较了各组的住院时间(LOS)、并发症和临床疗效:结果:共有 83 对临床基线数据相当的均衡患者。值得注意的是,FC 组患者的总体并发症(FC 组 20.5% vs FN 组 39.8%,P = 0.007)、主要并发症(FC 组 7.2% vs FN 组 19.3%,P = 0.022)和住院时间(FC 组 11.18 ± 5.32 vs FN 组 14.45 ± 4.68,P < 0.001)均显著低于 FN 组患者。此外,FC 组患者比 FN 组患者更早开始活动(FC 组为 2.14 ± 1.21,FN 组为 3.18 ± 1.73,P = 0.012)和排便(FC 组为 3.68 ± 1.24,FN 组为 4.17 ± 1.32,P = 0.031)。在临床疗效方面,FC 组和 FN 组患者在术后第 30 天(POD)Oswestry 失能指数(ODI)、第 30-90 天(POD)背部视觉模拟量表(VAS)和第 30、90 和 180 天(POD)腿部视觉模拟量表(VAS)达到最小临床重要差异(MCID)方面没有显著差异。然而,FC 组和 FN 组中,POD 90 和 180 的 ODI 以及 POD 180 的背部 VAS 符合 MCID 的患者明显更多:在这项回顾性队列研究中,我们发现与ERAS依从性较低的患者相比,ERAS依从性较高的一组体弱患者的总体并发症、主要并发症发生率较低,且住院时间较短。此外,ERAS依从性较高的虚弱患者能够更早地活动和排便。更重要的是,我们发现ERAS依从性较高的患者在POD 90和180时ODI达到MCID的人数以及在POD 180时背部VAS达到MCID的人数明显多于ERAS依从性较低的患者。
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引用次数: 0
Initial and Long-Term Prescribing of Opioids and Non-steroidal Anti-inflammatory Drugs Following Total Hip and Knee Arthroplasty. 全髋关节和膝关节置换术后阿片类药物和非甾体抗炎药的初始和长期处方。
IF 1.6 4区 医学 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2024-08-13 eCollection Date: 2024-01-01 DOI: 10.1177/21514593241266715
Melissa R Riester, Elliott Bosco, Francesca L Beaudoin, Stefan Gravenstein, Andrew J Schoenfeld, Vincent Mor, Andrew R Zullo

Introduction: Limited evidence exists on health system characteristics associated with initial and long-term prescribing of opioids and nonsteroidal anti-inflammatory drugs (NSAIDs) following total hip and knee arthroplasty (THA/TKA), and if these characteristics differ among individuals based on preoperative NSAID exposure. We identified orthopedic surgeon opioid prescribing practices, hospital characteristics, and regional factors associated with initial and long-term prescribing of opioids and NSAIDs among older adults receiving THA/TKA.

Materials and methods: This observational study included opioid-naïve Medicare beneficiaries aged ≥65 years receiving elective THA/TKA between January 1, 2014 and July 4, 2017. We examined initial (days 1-30 following THA/TKA) and long-term (days 90-180) opioid or NSAID prescribing, stratified by preoperative NSAID exposure. Risk ratios (RRs) for the associations between 10 health system characteristics and case-mix adjusted outcomes were estimated using multivariable Poisson regression models.

Results: The study population included 23,351 NSAID-naïve and 10,127 NSAID-prevalent individuals. Increases in standardized measures of orthopedic surgeon opioid prescribing generally decreased the risk of initial NSAID prescribing but increased the risk of long-term opioid prescribing. For example, among NSAID-naïve individuals, the RRs (95% confidence intervals [CIs]) for initial NSAID prescribing were 0.95 (0.93-0.97) for 1-2 orthopedic surgeon opioid prescriptions per THA/TKA procedure, 0.94 (0.92-0.97) for 3-4 prescriptions per procedure, and 0.91 (0.89-0.93) for 5+ opioid prescriptions per procedure (reference: <1 opioid prescription per procedure), while the RRs (95% CIs) for long-term opioid prescribing were 1.06 (1.04-1.08), 1.08 (1.06-1.11), and 1.13 (1.11-1.16), respectively. Variation in postoperative analgesic prescribing was observed across U.S. regions. For example, among NSAID-naïve individuals, the RR (95% CIs) for initial opioid prescribing were 0.98 (0.96-1.00) for Region 2 (New York), 1.09 (1.07-1.11) for Region 3 (Philadelphia), 1.07 (1.05-1.10) for Region 4 (Atlanta), 1.03 (1.01-1.05) for Region 5 (Chicago), 1.16 (1.13-1.18) for Region 6 (Dallas), 1.10 (1.08-1.12) for Region 7 (Kansas City), 1.09 (1.06-1.12) for Region 8 (Denver), 1.09 (1.07-1.12) for Region 9 (San Francisco), and 1.11 (1.08-1.13) for Region 10 (Seattle) (reference: Region 1 [Boston]). Hospital characteristics were not meaningfully associated with postoperative analgesic prescribing. The relationships between health system characteristics and postoperative analgesic prescribing were similar for NSAID-naïve and NSAID-prevalent participants.

Discussion: Future efforts aiming to improve the use of multimodal analgesia through increased NSAID prescribing and reduced long-term opioid prescribing following THA/TKA could consider targeting orthopedic

导言:关于全髋关节和膝关节置换术(THA/TKA)后阿片类药物和非甾体抗炎药(NSAIDs)的初始处方和长期处方相关的医疗系统特征,以及这些特征是否因术前非甾体抗炎药接触而在个体间存在差异的证据有限。我们确定了骨科医生开阿片类药物处方的做法、医院特点以及与接受 THA/TKA 的老年人初次和长期开阿片类药物和非甾体抗炎药相关的地区因素:这项观察性研究纳入了 2014 年 1 月 1 日至 2017 年 7 月 4 日期间接受择期 THA/TKA 的年龄≥65 岁、未使用过阿片类药物的医疗保险受益人。我们研究了阿片类药物或非甾体抗炎药的初始处方(THA/TKA 术后第 1-30 天)和长期处方(第 90-180 天),并根据术前非甾体抗炎药暴露情况进行了分层。使用多变量泊松回归模型估算了10个医疗系统特征与病例组合调整结果之间的风险比(RR):研究对象包括 23351 名未使用非甾体抗炎药的患者和 10127 名使用非甾体抗炎药的患者。骨科医生阿片类药物处方标准化指标的增加通常会降低初次使用非甾体抗炎药的风险,但会增加长期使用阿片类药物的风险。例如,在对非甾体抗炎药不敏感的人群中,每例 THA/TKA 手术中骨科医生开出 1-2 张阿片类药物处方的初始非甾体抗炎药处方风险率(95% 置信区间 [CIs])为 0.95(0.93-0.97),每例手术中开出 3-4 张处方的初始非甾体抗炎药处方风险率(95% 置信区间 [CIs])为 0.94(0.92-0.97),每例手术中开出 5 张以上阿片类药物处方的初始非甾体抗炎药处方风险率(95% 置信区间 [CIs])为 0.91(0.89-0.93):讨论:未来旨在通过增加非甾体抗炎药处方和减少THA/TKA术后长期阿片类药物处方来改善多模式镇痛使用的工作,可以考虑针对阿片类药物处方标准化程度较高的骨科医生:骨科医生阿片类药物处方标准和美国地区是老年医疗保险受益人在THA/TKA术后首次和长期开具阿片类药物和非甾体抗炎药处方的最大医疗系统预测因素。这些结果可以为今后的研究提供参考,这些研究将探讨不同地理区域和骨科医生阿片类药物处方水平的镇痛处方存在差异的原因。
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引用次数: 0
Patient Satisfaction Following Non-Operative Treatment of Geriatric Hip Fractures: A Case-Control Study. 老年髋部骨折非手术治疗后的患者满意度:病例对照研究
IF 1.6 4区 医学 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2024-08-13 eCollection Date: 2024-01-01 DOI: 10.1177/21514593241273312
Benjamin R Wiseley, Edward D Shin, Gabrielle R Kuhn, Scott J Hetzel, Kristina P Johnson, David C Goodspeed, Christopher J Doro, Paul S Whiting

Introduction: A minority of geriatric hip fracture patients pursue non-operative treatment. Compared with surgical patients, non-operative patients have higher mortality rates. However, patient satisfaction following non-operative vs operative treatment has not been investigated extensively. The purpose of this study was to compare satisfaction among non-operatively vs operatively treated hip fracture patients.

Methods: We identified patients aged 60+ years with proximal femur fractures treated over a 10-year period. Excluded were patients with isolated greater/lesser trochanteric fractures. Patients or relatives were asked to complete a 6-question survey about their treatment satisfaction.

Results: Survey responses from 56 operative and 28 non-operative patients were recorded. Overall, 91.1% of operative and 82.1% of non-operative patients were satisfied with their treatment course (P = 0.260). However, only 71.4% of non-operative patients were satisfied with treatment option explanations vs 83.9% of operative patients (P = 0.014). While only 64.3% of non-operative respondents were satisfied with the ultimate treatment outcome (vs 85.7% of operative patients, P = 0.025), 89.3% of patients in each cohort would choose the same treatment plan again.

Discussion: Our findings highlight the complexity of defining patient satisfaction, particularly in a geriatric hip fracture population. Unlike previous studies, we chose a direct approach to quantifying patient satisfaction by asking participants specifically about satisfaction with treatment outcome and the overall treatment course. Additional survey questions were then included to assess factors considered important in treatment satisfaction, such as health care provider treatment explanations, post-treatment mobility, and palliative care service involvement.

Conclusions: We identified significant differences between non-operatively and operatively treated geriatric hip fracture patients regarding satisfaction with the explanation of treatment options, and ultimate treatment outcomes. There was no significant difference in overall satisfaction with the treatment course or likelihood of choosing the same treatment again. Further research investigating patient satisfaction following geriatric hip fracture treatment is warranted.

导言:少数老年髋部骨折患者接受非手术治疗。与手术患者相比,非手术患者的死亡率更高。然而,非手术治疗与手术治疗后患者的满意度尚未得到广泛调查。本研究旨在比较非手术治疗与手术治疗髋部骨折患者的满意度:我们确定了在 10 年内接受治疗的 60 岁以上股骨近端骨折患者。不包括孤立的大转子/小转子骨折患者。患者或其亲属被要求完成一份包含 6 个问题的治疗满意度调查:结果:共记录了56名手术患者和28名非手术患者的调查反馈。总体而言,91.1%的手术患者和82.1%的非手术患者对治疗过程表示满意(P = 0.260)。然而,只有 71.4% 的非手术患者对治疗方案的解释感到满意,而手术患者的满意度为 83.9%(P = 0.014)。虽然只有 64.3% 的非手术受访者对最终治疗结果表示满意(手术患者的满意度为 85.7%,P = 0.025),但每个组群中都有 89.3% 的患者会再次选择相同的治疗方案:我们的研究结果凸显了界定患者满意度的复杂性,尤其是在老年髋部骨折人群中。与之前的研究不同,我们选择了一种直接量化患者满意度的方法,具体询问参与者对治疗结果和整个治疗过程的满意度。此外,我们还加入了其他调查问题,以评估被认为对治疗满意度很重要的因素,如医疗服务提供者的治疗解释、治疗后的活动能力以及姑息治疗服务的参与情况等:我们发现,非手术治疗和手术治疗的老年髋部骨折患者对治疗方案解释和最终治疗结果的满意度存在明显差异。在对治疗过程的总体满意度或再次选择相同治疗方法的可能性方面没有明显差异。有必要对老年髋部骨折治疗后患者的满意度进行进一步研究。
{"title":"Patient Satisfaction Following Non-Operative Treatment of Geriatric Hip Fractures: A Case-Control Study.","authors":"Benjamin R Wiseley, Edward D Shin, Gabrielle R Kuhn, Scott J Hetzel, Kristina P Johnson, David C Goodspeed, Christopher J Doro, Paul S Whiting","doi":"10.1177/21514593241273312","DOIUrl":"10.1177/21514593241273312","url":null,"abstract":"<p><strong>Introduction: </strong>A minority of geriatric hip fracture patients pursue non-operative treatment. Compared with surgical patients, non-operative patients have higher mortality rates. However, patient satisfaction following non-operative vs operative treatment has not been investigated extensively. The purpose of this study was to compare satisfaction among non-operatively vs operatively treated hip fracture patients.</p><p><strong>Methods: </strong>We identified patients aged 60+ years with proximal femur fractures treated over a 10-year period. Excluded were patients with isolated greater/lesser trochanteric fractures. Patients or relatives were asked to complete a 6-question survey about their treatment satisfaction.</p><p><strong>Results: </strong>Survey responses from 56 operative and 28 non-operative patients were recorded. Overall, 91.1% of operative and 82.1% of non-operative patients were satisfied with their treatment course (<i>P</i> = 0.260). However, only 71.4% of non-operative patients were satisfied with treatment option explanations vs 83.9% of operative patients (<i>P</i> = 0.014). While only 64.3% of non-operative respondents were satisfied with the ultimate treatment outcome (vs 85.7% of operative patients, <i>P</i> = 0.025), 89.3% of patients in each cohort would choose the same treatment plan again.</p><p><strong>Discussion: </strong>Our findings highlight the complexity of defining patient satisfaction, particularly in a geriatric hip fracture population. Unlike previous studies, we chose a direct approach to quantifying patient satisfaction by asking participants specifically about satisfaction with treatment outcome and the overall treatment course. Additional survey questions were then included to assess factors considered important in treatment satisfaction, such as health care provider treatment explanations, post-treatment mobility, and palliative care service involvement.</p><p><strong>Conclusions: </strong>We identified significant differences between non-operatively and operatively treated geriatric hip fracture patients regarding satisfaction with the explanation of treatment options, and ultimate treatment outcomes. There was no significant difference in overall satisfaction with the treatment course or likelihood of choosing the same treatment again. Further research investigating patient satisfaction following geriatric hip fracture treatment is warranted.</p>","PeriodicalId":48568,"journal":{"name":"Geriatric Orthopaedic Surgery & Rehabilitation","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11322922/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141983599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of the COVID-19 Pandemic on One-Year Mortality in Geriatric Hip Fracture: A Retrospective Cohort Study. COVID-19 大流行对老年髋部骨折患者一年死亡率的影响:回顾性队列研究
IF 1.6 4区 医学 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2024-08-13 eCollection Date: 2024-01-01 DOI: 10.1177/21514593241273124
Eşref Selçuk, Murat Erem, Emine Gökçen Selçuk, Oğuz Mercan

Introduction: The COVID-19 pandemic has profoundly impacted global healthcare systems, necessitating substantial shifts in patient care strategies. The pandemic's onset led to drastic operational changes in hospitals, including reduced bed capacity and staffing levels, which could have further influenced the mortality outcomes for geriatric patients. The study aimed to assess the impact of the COVID-19 pandemic on 1-year mortality rates of surgically treated geriatric hip fractures.

Methods: This retrospective, single-center cohort study included 346 participants aged 65 and above who underwent surgical treatment for hip fractures. We compared mortality rates between the pre-COVID and COVID eras. Data included demographics, treatment, complications, and COVID-19 status. The independent samples t test and Chi-square tests (or Fisher's exact test) were used for comparisons for era cohorts. Survival probabilities were assessed using Kaplan-Meier, while multivariate analysis identified mortality predictors.

Results: 175 patients were included in the pre-COVID era, and 171 patients were included in the COVID era. During the COVID era, the 30-day mortality rate was 11.7% (compared to 13.7% in the pre-COVID era, p = 0.573), and the 1-year mortality rate was 43.9% (compared to 49.1% in the pre-COVID era, p = 0.325). The overall 1-year mortality rate was 46.5%. Patients who underwent surgery within 48 hours had a higher 1-year survival rate (60.5%) compared to those with delayed surgery (51.2%), p = 0.031. Additionally, patients not admitted to the ICU had a higher 1-year survival rate (74.7%) than those who were admitted (44.9%), p < 0.001. 70.1% of the total deaths occurred within the first 90 days.

Conclusion: Elderly patients with hip fractures experienced high mortality rates before and during the pandemic. This study demonstrates that the 1-year mortality rates of geriatric hip fractures were not significantly affected by the pandemic. The findings emphasize the importance of pandemic preparedness and prompt surgeries and attentive ICU care in reducing mortality rates.

导言:COVID-19 大流行对全球医疗保健系统产生了深远影响,使患者护理策略必须做出重大改变。大流行导致医院的运营发生了巨大变化,包括病床容量和人员配置水平下降,这可能会进一步影响老年病患者的死亡率。本研究旨在评估 COVID-19 大流行对接受手术治疗的老年髋部骨折患者 1 年死亡率的影响:这项回顾性单中心队列研究纳入了 346 名 65 岁及以上接受髋部骨折手术治疗的患者。我们比较了 COVID 前和 COVID 时代的死亡率。数据包括人口统计学、治疗、并发症和 COVID-19 状态。采用独立样本 t 检验和卡方检验(或费雪精确检验)对不同时代的队列进行比较。采用 Kaplan-Meier 法评估生存概率,并通过多变量分析确定死亡率预测因素:结果:175 名患者被纳入前 COVID 时代,171 名患者被纳入 COVID 时代。在 COVID 时代,30 天死亡率为 11.7%(前 COVID 时代为 13.7%,P = 0.573),1 年死亡率为 43.9%(前 COVID 时代为 49.1%,P = 0.325)。1年总死亡率为46.5%。48 小时内接受手术的患者 1 年生存率(60.5%)高于延迟手术的患者(51.2%),p = 0.031。此外,未入住重症监护室的患者的 1 年存活率(74.7%)高于入住重症监护室的患者(44.9%),P < 0.001。70.1%的死亡发生在最初的90天内:结论:髋部骨折的老年患者在大流行之前和期间的死亡率都很高。这项研究表明,大流行对老年髋部骨折患者的 1 年死亡率影响不大。研究结果强调了做好大流行准备、及时手术和重症监护室的精心护理对降低死亡率的重要性。
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引用次数: 0
A 10-Year Experience of an Integrated Geriatric Hip Fracture Treatment Protocol: Outcomes at a Minimum 2-Year Follow-Up. 老年髋部骨折综合治疗方案的 10 年经验:至少两年随访的结果。
IF 1.6 4区 医学 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2024-08-09 eCollection Date: 2024-01-01 DOI: 10.1177/21514593241273155
Anna Hayward-Livingston, Yagiz Ozdag, David Kolessar, Jacob Weinberg, Arpitha Pamul, Kenneth Koury, Anthony Balsamo

Introduction: Increasing incidence of fragility fractures has spurred development of protocols, largely focused on peri-operative care, with numerous proven benefits. The purpose of this investigation was to evaluate outcomes of our hip fracture treatment program regarding successful protocol implementation, compliance, effect on subsequent fracture rates, and mortality during the first decade of adoption.

Methods: A retrospective review identified patients >65 years old with fragility hip fractures between 2010 and 2022. The HiROC (+) cohort consisted of patients who received a "High-Risk Osteoporosis Clinic" (HiROC) referral for bone health evaluation and bisphosphonate initiation as indicated. Additional fracture rates and mortality at 3 years were calculated. Protocol implementation and compliance over the first 10 years was analyzed in the four identified cohorts.

Results: A total of 1671 fragility hip fractures were identified, with 386 excluded due to insufficient follow-up, with an average age of 81.6 years and a median follow-up of 36.4 months. Of the 1280 included cases, 56% (n = 717) had a HiROC referral placed. HiROC(+) groups had lower subsequent fracture rates at two years, compared to those without referral (28% vs 13%, P < 0.0001) and those completing more steps of the protocol had lower subsequent fracture rates (28% vs 15% vs 13% vs 5%, P < 0.0001). No statistically significant difference was observed between the cohorts for anatomic site of subsequent fractures.

Discussion: Greater than half of all eligible patients were successfully captured by the protocol. Patients completing more steps of the protocol had lower subsequent fracture rates. Captured patients demonstrated reduced mortality rates when compared to current literature.

Conclusion: Successful implementation of this geriatric hip fracture protocol was associated with reduced additional fractures and mortality rates. Identifying steps of process failures in the protocol can provide opportunities for increased compliance and reduction in future fracture occurrences.

介绍:脆性骨折发病率的增加促使了相关方案的制定,这些方案主要集中在围手术期护理方面,已被证实具有诸多益处。这项调查的目的是评估我们的髋部骨折治疗方案在采用的前十年中在方案的成功实施、依从性、对后续骨折发生率的影响以及死亡率等方面的成果:一项回顾性研究确定了 2010 年至 2022 年间年龄大于 65 岁的脆性髋部骨折患者。HiROC(+)队列包括接受 "高危骨质疏松症门诊"(HiROC)转诊的患者,这些患者将接受骨健康评估,并根据指示开始使用双膦酸盐。计算了额外的骨折率和 3 年的死亡率。对已确定的四个队列中前 10 年的方案执行情况和依从性进行了分析:共发现 1671 例脆性髋部骨折,其中 386 例因随访时间不足而被排除,平均年龄为 81.6 岁,中位随访时间为 36.4 个月。在纳入的 1280 个病例中,56%(n = 717)的病例接受了 HiROC 转诊。与未转诊的患者相比,HiROC(+)组患者两年后的骨折率较低(28% vs 13%,P < 0.0001),完成更多方案步骤的患者两年后的骨折率较低(28% vs 15% vs 13% vs 5%,P < 0.0001)。在后续骨折的解剖部位方面,各组间未观察到有统计学意义的差异:讨论:所有符合条件的患者中,超过一半的患者都成功完成了方案。完成更多方案步骤的患者后续骨折发生率较低。与现有文献相比,所采集患者的死亡率有所降低:结论:成功实施老年髋部骨折治疗方案可降低新增骨折率和死亡率。识别方案中流程失败的步骤可为提高依从性和减少未来骨折的发生提供机会。
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引用次数: 0
The Utility and Necessity for Radiographic Follow-Up After Arthroplasty for Geriatric Neck of Femur Fractures. 老年股骨颈骨折关节置换术后放射学随访的实用性和必要性。
IF 1.6 4区 医学 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2024-08-09 eCollection Date: 2024-01-01 DOI: 10.1177/21514593241273208
Don Jun Rui Koh, Kuei Siong Andy Yeo, Kam King Charles Kon, Ing How Moo

Background: Hip fractures are a common and debilitating condition posing not only a huge health care but also socioeconomic burden. Surgical management for a neck of femur fracture is typically with arthroplasty in the form of total hip arthroplasty or hip hemiarthroplasty. Serial radiographs are typically performed routinely as part of follow-up to look for complications, although their clinical utility in asymptomatic patients is yet to be validated. Our paper therefore aims to review the utility and necessity of radiographic follow-up following arthroplasty for NOF fractures.

Materials and methods: Patients who underwent operative management for acute fragility neck of femur fractures in the year from 1st January 2018 to 31st December 2018 at the author's institution were identified. All patients who underwent surgery, and had at least one pre and one post-operative plain film radiograph of the affected hip were included in this study. Exclusion criteria included patients who had undergone surgery for chronic fractures, avascular necrosis of the femoral head, mortality within 1 year, peri-prosthetic fractures, pathological fractures from metastases, had concomitant injuries, or had inaccessible or incomplete records. Clinical records were assessed for the number of visits, an abnormal presenting history or clinical examination, as well as changes in management of the patient. The number and type of radiographs were also assessed, and each radiograph analyzed for abnormal findings.

Results: A total of 157 patients were included in our study with a mean age of 79.5 at the time of surgery, and a mean follow up of 17.3 months. Data was collected from 626 clinical visits and a total of 973 radiographs. The 3 abnormal radiographic series identified with a corresponding normal consult did not result in a change of management for the patient. A negative change in management was only observed in 1 patient with an abnormal consult and a corresponding normal radiograph.

Conclusion: Post-operative complications following arthroplasty for NOF fractures are likely to result in a symptomatic presentation of the patient. Routine radiographic follow-up provides limited utility in asymptomatic patients and should only be performed if clinically indicated.

背景:髋部骨折是一种常见的致残性疾病,不仅给医疗保健带来巨大负担,也给社会经济带来沉重负担。股骨颈骨折的手术治疗通常采用全髋关节置换术或髋关节半置换术。作为随访的一部分,通常会常规进行序列X光片检查以发现并发症,但其对无症状患者的临床效用仍有待验证。因此,我们的论文旨在回顾 NOF 骨折关节置换术后射线随访的实用性和必要性:确定了 2018 年 1 月 1 日至 2018 年 12 月 31 日期间在作者所在机构接受手术治疗的急性股骨颈脆性骨折患者。所有接受手术治疗的患者均纳入本研究,且至少有一张术前和一张术后患侧髋关节平片X光片。排除标准包括因慢性骨折、股骨头无血管性坏死、1年内死亡、假体周围骨折、转移瘤引起的病理性骨折、合并损伤、无法获取或记录不完整而接受手术的患者。临床记录的评估包括就诊次数、异常病史或临床检查,以及患者治疗过程中的变化。此外,还评估了X光片的数量和类型,并分析了每张X光片的异常发现:我们的研究共纳入了 157 名患者,手术时的平均年龄为 79.5 岁,平均随访时间为 17.3 个月。我们从 626 次临床就诊和 973 张放射照片中收集了数据。发现的 3 个异常放射系列与相应的正常会诊没有导致患者治疗方案的改变。只有 1 名患者的会诊结果异常,但相应的 X 光片检查结果正常:结论:NOF 骨折关节置换术后并发症很可能导致患者出现症状。对无症状患者进行常规X光片随访的作用有限,只有在有临床指征时才应进行。
{"title":"The Utility and Necessity for Radiographic Follow-Up After Arthroplasty for Geriatric Neck of Femur Fractures.","authors":"Don Jun Rui Koh, Kuei Siong Andy Yeo, Kam King Charles Kon, Ing How Moo","doi":"10.1177/21514593241273208","DOIUrl":"10.1177/21514593241273208","url":null,"abstract":"<p><strong>Background: </strong>Hip fractures are a common and debilitating condition posing not only a huge health care but also socioeconomic burden. Surgical management for a neck of femur fracture is typically with arthroplasty in the form of total hip arthroplasty or hip hemiarthroplasty. Serial radiographs are typically performed routinely as part of follow-up to look for complications, although their clinical utility in asymptomatic patients is yet to be validated. Our paper therefore aims to review the utility and necessity of radiographic follow-up following arthroplasty for NOF fractures.</p><p><strong>Materials and methods: </strong>Patients who underwent operative management for acute fragility neck of femur fractures in the year from 1<sup>st</sup> January 2018 to 31<sup>st</sup> December 2018 at the author's institution were identified. All patients who underwent surgery, and had at least one pre and one post-operative plain film radiograph of the affected hip were included in this study. Exclusion criteria included patients who had undergone surgery for chronic fractures, avascular necrosis of the femoral head, mortality within 1 year, peri-prosthetic fractures, pathological fractures from metastases, had concomitant injuries, or had inaccessible or incomplete records. Clinical records were assessed for the number of visits, an abnormal presenting history or clinical examination, as well as changes in management of the patient. The number and type of radiographs were also assessed, and each radiograph analyzed for abnormal findings.</p><p><strong>Results: </strong>A total of 157 patients were included in our study with a mean age of 79.5 at the time of surgery, and a mean follow up of 17.3 months. Data was collected from 626 clinical visits and a total of 973 radiographs. The 3 abnormal radiographic series identified with a corresponding normal consult did not result in a change of management for the patient. A negative change in management was only observed in 1 patient with an abnormal consult and a corresponding normal radiograph.</p><p><strong>Conclusion: </strong>Post-operative complications following arthroplasty for NOF fractures are likely to result in a symptomatic presentation of the patient. Routine radiographic follow-up provides limited utility in asymptomatic patients and should only be performed if clinically indicated.</p>","PeriodicalId":48568,"journal":{"name":"Geriatric Orthopaedic Surgery & Rehabilitation","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11316266/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141917811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Comprehensive Rehabilitation Training Based on Balance Function on Postoperative Recovery and Function of Hip Fracture in the Elderly: A Systematic Review and Meta-Analysis. 基于平衡功能的综合康复训练对老年人髋部骨折术后恢复和功能的影响:系统回顾与元分析》。
IF 1.6 4区 医学 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2024-07-29 eCollection Date: 2024-01-01 DOI: 10.1177/21514593241261506
Hai Chang, Chunliang Luan, Chen Li

Introduction: In China, the proportion of the elderly population is gradually increasing, followed by the increasing medical demands of elderly patients. Hip fracture is a common fracture in the elderly. The elderly are prone to serious postoperative complications, resulting in failure to restore normal hip function, which seriously affects patients' quality of life and further increases their mortality rate. Thus, hip fracture represents a remarkable public health issue within the realm of geriatric medical care.

Significance: This study systematically evaluated the impact of comprehensive rehabilitation training, with a focus on balance function, on elderly individuals with hip fractures' postoperative recovery and functional outcomes.

Result: Results showed a significant difference in BBS scores favoring comprehensive rehabilitation training based on balance function over conventional intervention. Similarly, AM-PAC scores favored the balance-focused training. TUTG meta-analysis indicated its adoption in comprehensive rehabilitation training. FIM scores showed improvement with balance-focused training. Harris score meta-analysis also favored this approach. A funnel plot analysis revealed potential publication bias, likely due to study heterogeneity and limited publications.

Conclusions: In conclusion, comprehensive rehabilitation training centered around balance function displayed clinical efficacy in enhancing postoperative hip joint function in elderly hip fracture patients. This approach improved balance, coordination, and posture control, facilitating lower limb function recovery and overall prognosis. It holds promise as a valuable treatment approach.

引言在中国,老年人口的比例逐渐增加,老年患者的医疗需求也随之增加。髋部骨折是老年人常见的骨折。老年人术后容易出现严重的并发症,导致髋关节功能无法恢复正常,严重影响患者的生活质量,进一步增加患者的死亡率。因此,髋部骨折是老年医疗领域中一个重要的公共卫生问题:本研究系统评估了以平衡功能为重点的综合康复训练对髋部骨折老人术后恢复和功能预后的影响:结果:结果显示,基于平衡功能的综合康复训练与传统干预相比,在 BBS 评分上存在明显差异。同样,AM-PAC 评分也倾向于以平衡为重点的训练。TUTG荟萃分析表明,该方法可用于综合康复训练。FIM 评分显示,以平衡为重点的训练可改善患者的身体状况。Harris 评分荟萃分析也支持这种方法。漏斗图分析揭示了潜在的发表偏倚,这可能是由于研究的异质性和有限的发表:总之,以平衡功能为中心的综合康复训练在增强老年髋部骨折患者术后髋关节功能方面具有临床疗效。这种方法改善了患者的平衡、协调和姿势控制能力,有利于下肢功能的恢复和整体预后。它有望成为一种有价值的治疗方法。
{"title":"Effect of Comprehensive Rehabilitation Training Based on Balance Function on Postoperative Recovery and Function of Hip Fracture in the Elderly: A Systematic Review and Meta-Analysis.","authors":"Hai Chang, Chunliang Luan, Chen Li","doi":"10.1177/21514593241261506","DOIUrl":"10.1177/21514593241261506","url":null,"abstract":"<p><strong>Introduction: </strong>In China, the proportion of the elderly population is gradually increasing, followed by the increasing medical demands of elderly patients. Hip fracture is a common fracture in the elderly. The elderly are prone to serious postoperative complications, resulting in failure to restore normal hip function, which seriously affects patients' quality of life and further increases their mortality rate. Thus, hip fracture represents a remarkable public health issue within the realm of geriatric medical care.</p><p><strong>Significance: </strong>This study systematically evaluated the impact of comprehensive rehabilitation training, with a focus on balance function, on elderly individuals with hip fractures' postoperative recovery and functional outcomes.</p><p><strong>Result: </strong>Results showed a significant difference in BBS scores favoring comprehensive rehabilitation training based on balance function over conventional intervention. Similarly, AM-PAC scores favored the balance-focused training. TUTG meta-analysis indicated its adoption in comprehensive rehabilitation training. FIM scores showed improvement with balance-focused training. Harris score meta-analysis also favored this approach. A funnel plot analysis revealed potential publication bias, likely due to study heterogeneity and limited publications.</p><p><strong>Conclusions: </strong>In conclusion, comprehensive rehabilitation training centered around balance function displayed clinical efficacy in enhancing postoperative hip joint function in elderly hip fracture patients. This approach improved balance, coordination, and posture control, facilitating lower limb function recovery and overall prognosis. It holds promise as a valuable treatment approach.</p>","PeriodicalId":48568,"journal":{"name":"Geriatric Orthopaedic Surgery & Rehabilitation","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11289819/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141861300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Frailty Syndrome on Osteoporosis, Focusing on the Mediating Effect of Muscle Strength and Balance in Community-Dwelling Older Adults (≥60 years) in Iran: Results From the Amirkola Health and Aging Project Cohort Study. 伊朗社区老年人(≥60 岁)的虚弱综合征对骨质疏松症的影响,重点关注肌肉力量和平衡的中介效应:阿米尔科拉健康与老龄化项目队列研究的结果。
IF 1.6 4区 医学 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2024-07-25 eCollection Date: 2024-01-01 DOI: 10.1177/21514593241264647
Abbas Shamsalinia, Seyed Reza Hosseini, Ali Bijani, Reza Ghadimi, Mohammad Reza Kordbageri, Kiyana Saadati, Fatemeh Ghaffari

Introduction: For older adults, maintaining muscle strength and balance is crucial to preserve an upright posture and independently manage their basic activities of daily living (ADL). This study aimed to examine whether muscle strength and balance mediate the relationship between frailty syndrome (FS) and osteoporosis in a large sample of community-dwelling older adults.

Material and methods: This cross-sectional study is part of the second phase (2016-2017) of the Amirkola Health and Ageing Project (AHAP), a cohort study conducted on all elderly aged 60 and over in Amirkola, Northern Iran, since 2011. Data from 2018 older adults were collected by a trained person using bone mineral density (BMD), frailty index, activities of daily living (ADL), instrumental activities of daily living (IADL), handgrip strength (HGS), quadriceps muscle strength (QMS), Berg Balance Scale (BBS), and Timed Up and Go test (TUG test) and analyzed using analysis of variance, chi-square, and path analysis tests.

Results: The mean indices of femoral neck BMD and lumbar spine BMD, HGS, QMS, BBS, ADL, and IADL were lower in the frail older adults than in the pre-frail and non-frail older adults. In addition, the mean TUG test level was higher in the frail older adults than in the non-frail and pre-frail older adults. The results of the present study have indicated that frailty is significantly related to osteoporosis, and that balance and muscle strength can predict osteoporosis; these variables play a mediating role in the relationship between frailty and osteoporosis.

Conclusion: From the results of the present study, it can be concluded that frailty may increase the odds of osteoporosis. The results of the current study have indicated that balance (BBS and TUG test) and muscle strength (HGS and QMS) are associated with osteoporosis and these variables play a mediating role in the relationship between frailty and osteoporosis.

导言:对于老年人来说,保持肌肉力量和平衡对于保持直立姿势和独立完成基本日常生活活动(ADL)至关重要。本研究旨在研究在社区居住的老年人中,肌肉力量和平衡是否能调节虚弱综合征(FS)和骨质疏松症之间的关系:这项横断面研究是阿米尔科拉健康与老龄化项目(AHAP)第二阶段(2016-2017 年)的一部分,该项目是一项自 2011 年以来在伊朗北部阿米尔科拉对所有 60 岁及以上老年人进行的队列研究。由一名受过培训的人员通过骨矿密度(BMD)、虚弱指数、日常生活活动(ADL)、工具性日常生活活动(IADL)、手握力(HGS)、股四头肌力(QMS)、伯格平衡量表(BBS)和定时上下楼测试(TUG 测试)收集了 2018 名老年人的数据,并使用方差分析、卡方差分析和路径分析测试对数据进行了分析:结果:体弱老年人的股骨颈 BMD 和腰椎 BMD、HGS、QMS、BBS、ADL 和 IADL 的平均指数均低于未体弱老年人和非体弱老年人。此外,体弱老年人的平均 TUG 测试水平也高于非体弱和未体弱老年人。本研究结果表明,虚弱与骨质疏松症有显著关系,平衡和肌肉力量可预测骨质疏松症;这些变量在虚弱与骨质疏松症的关系中起着中介作用:从本研究的结果可以得出结论,虚弱可能会增加骨质疏松症的发生几率。本研究结果表明,平衡能力(BBS 和 TUG 测试)和肌肉力量(HGS 和 QMS)与骨质疏松症有关,这些变量在体弱和骨质疏松症之间的关系中起着中介作用。
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引用次数: 0
Prevalence of Common Metabolic Bone Diseases Diagnosed by Dual-Energy X-Ray Absorptiometry Scanning and Blood Test in Outpatients With Osteoarthritis the Knee. 膝关节骨性关节炎门诊患者通过双能量 X 射线吸收扫描和血液检测诊断出的常见代谢性骨病患病率
IF 1.6 4区 医学 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2024-07-20 eCollection Date: 2024-01-01 DOI: 10.1177/21514593241266377
Napat Chaiyavech, Satit Thiengwittayaporn, Natthapong Hongku

Introduction: Osteoarthritis of the knee (OA knee) is a common geriatric disease that require total knee arthroplasty. Periprosthetic fracture is one of the common complications, which is strongly related to metabolic bone disease.

Materials and methods: We conducted a prospective study on 291 outpatients with OA knee between November 2020 and April 2021. Baseline characteristics, dual-energy X-ray absorptiometry and blood test results were analysed using logistic regression analysis and expressed as odds ratio, 95% confidence intervals and P-values.

Results: Overall metabolic bone diseases were found in 82.91% of patients. Vitamin D insufficiency (53.38%) was the most prevalent, followed by osteopenia (44.38%), impaired renal function (26.69%), and osteoporosis (17.45%). Risk factors of vitamin D insufficiency are age ≥71 years (OR 0.33, P = 0.003) and bilateral affected side (OR 1.99, P = 0.007). For osteopenia and osteoporosis, risk factors were age, body mass index, affected side, and chronic kidney disease (P < 0.05).

Discussion: In the aspect of Vit D insufficiency, age>70 and bilateral OA knee were significantly related in many ways, such as reduction in cutaneous synthesis and daily exposure to sunlight and various diseases, including CKD and GI malabsorption. The risk factors of osteopenia and osteoporosis can be explained throughout several mechanisms. For instance, abnormality in hormone and cytokines metabolism will lead to the increase in adipocyte differentiation and fat accumulation. And that situation may lead to the decrease in osteoblast differentiation and increased osteoclast activity which could lead to negative impact on bone strength.

Conclusions: Metabolic bone diseases were common in most patients with OA knee, and the insufficiency in amount of vitamin D(serum 25-hydroxyvitamin D), osteoporosis, and osteopenia conditions were mainly identified. These preventable conditions have risk factors that are mostly correctable These preventable conditions have risk factors that are mostly correctable, for example gain more outdoor activities, consume vitamin D supplement or start osteoporosis treatment program. Further analysis is necessary to establish solid evidence in the comparison of risk factors between the OA and non-OA groups.

简介膝关节骨性关节炎(OA)是一种需要进行全膝关节置换术的常见老年病。假体周围骨折是常见的并发症之一,与代谢性骨病密切相关:我们在 2020 年 11 月至 2021 年 4 月期间对 291 名膝关节 OA 门诊患者进行了前瞻性研究。采用逻辑回归分析法对基线特征、双能 X 射线吸收测量和血液检测结果进行分析,并以几率比、95% 置信区间和 P 值表示:82.91%的患者患有代谢性骨病。维生素 D 不足(53.38%)最常见,其次是骨质疏松症(44.38%)、肾功能受损(26.69%)和骨质疏松症(17.45%)。维生素 D 不足的风险因素是年龄≥71 岁(OR 0.33,P = 0.003)和双侧受累(OR 1.99,P = 0.007)。骨质疏松症和骨质疏松症的风险因素是年龄、体重指数、患侧和慢性肾病(P < 0.05):讨论:在维生素 D 不足方面,年龄大于 70 岁和双侧膝关节 OA 在许多方面都有显著相关性,如皮肤合成减少、日常日光照射和各种疾病,包括慢性肾脏病和消化道吸收不良。骨质疏松症和骨质疏松症的风险因素可以通过多种机制来解释。例如,激素和细胞因子代谢异常会导致脂肪细胞分化和脂肪堆积增加。这种情况可能会导致成骨细胞分化减少和破骨细胞活性增加,从而对骨质强度产生负面影响:大多数膝关节 OA 患者普遍存在代谢性骨病,主要表现为维生素 D(血清 25- 羟维生素 D)含量不足、骨质疏松症和骨质疏松。这些可预防疾病的风险因素大多是可以纠正的,如增加户外活动、补充维生素 D 或开始骨质疏松症治疗计划。在比较 OA 组和非 OA 组之间的风险因素时,有必要进行进一步分析,以建立可靠的证据。
{"title":"Prevalence of Common Metabolic Bone Diseases Diagnosed by Dual-Energy X-Ray Absorptiometry Scanning and Blood Test in Outpatients With Osteoarthritis the Knee.","authors":"Napat Chaiyavech, Satit Thiengwittayaporn, Natthapong Hongku","doi":"10.1177/21514593241266377","DOIUrl":"https://doi.org/10.1177/21514593241266377","url":null,"abstract":"<p><strong>Introduction: </strong>Osteoarthritis of the knee (OA knee) is a common geriatric disease that require total knee arthroplasty. Periprosthetic fracture is one of the common complications, which is strongly related to metabolic bone disease.</p><p><strong>Materials and methods: </strong>We conducted a prospective study on 291 outpatients with OA knee between November 2020 and April 2021. Baseline characteristics, dual-energy X-ray absorptiometry and blood test results were analysed using logistic regression analysis and expressed as odds ratio, 95% confidence intervals and <i>P</i>-values.</p><p><strong>Results: </strong>Overall metabolic bone diseases were found in 82.91% of patients. Vitamin D insufficiency (53.38%) was the most prevalent, followed by osteopenia (44.38%), impaired renal function (26.69%), and osteoporosis (17.45%). Risk factors of vitamin D insufficiency are age ≥71 years (OR 0.33, <i>P</i> = 0.003) and bilateral affected side (OR 1.99, <i>P</i> = 0.007). For osteopenia and osteoporosis, risk factors were age, body mass index, affected side, and chronic kidney disease (<i>P</i> < 0.05).</p><p><strong>Discussion: </strong>In the aspect of Vit D insufficiency, age>70 and bilateral OA knee were significantly related in many ways, such as reduction in cutaneous synthesis and daily exposure to sunlight and various diseases, including CKD and GI malabsorption. The risk factors of osteopenia and osteoporosis can be explained throughout several mechanisms. For instance, abnormality in hormone and cytokines metabolism will lead to the increase in adipocyte differentiation and fat accumulation. And that situation may lead to the decrease in osteoblast differentiation and increased osteoclast activity which could lead to negative impact on bone strength.</p><p><strong>Conclusions: </strong>Metabolic bone diseases were common in most patients with OA knee, and the insufficiency in amount of vitamin D(serum 25-hydroxyvitamin D), osteoporosis, and osteopenia conditions were mainly identified. These preventable conditions have risk factors that are mostly correctable These preventable conditions have risk factors that are mostly correctable, for example gain more outdoor activities, consume vitamin D supplement or start osteoporosis treatment program. Further analysis is necessary to establish solid evidence in the comparison of risk factors between the OA and non-OA groups.</p>","PeriodicalId":48568,"journal":{"name":"Geriatric Orthopaedic Surgery & Rehabilitation","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11268085/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141761796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Geriatric Orthopaedic Surgery & Rehabilitation
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