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Barretos’ County Matrix Support in Public Health - Deployment and Initial Results 巴雷托斯县公共卫生矩阵支持——部署和初步成果
IF 1.6 4区 医学 Q2 Nursing Pub Date : 2019-01-01 DOI: 10.15761/hpc.1000174
Guilherme Carvalho Freire, Martins Fideles dos Santos Neto, A. Sankarankutty, Miriam Cristina Marchioreto de Oliveira, Marilene Oliveira Simeão, Nathalia Figueiredo Maia, Nicole Mayara Dias Souza, A. Longatto-Filho, J. L. Brisotti, E. Mauad
Aims: Brazil offers universal, integral and free healthcare to all its citizens through its Unified Health System (SUS). Within Brazil, the state of São Paulo has the most complex health network and comes closest to offering the comprehensive healthcare as per the guidelines of SUS. However, constraints to the system include a lack of integration and coordination between the basic healthcare network and specialty outpatient clinics, which hampers both proper access to specialties as well the return to basic care. This inefficiency feeds a pernicious cycle leading to waiting times for specialty care in excess of two years. Methods: In this article we describe the step-by-step implementation of an institutional and matrix support system between specialties and primary care in the county of Barretos, São Paulo, Brazil. Results: The initial results of this coordination and integration demonstrate the feasibility and excellent results such as the reduction in the need for referral to specialty clinics of up to 87%. Conclusion: Matrix support improved significantly the medical care and potentially can reduce costs as well. *Correspondence to: Adhemar Longatto-Filho, PhD, Molecular Oncology Research Center, Barretos Cancer Hospital/Pio XII Foundation, Brazil, Surgical Sciences Research Domain Life and Health Sciences Research Institute (ICVS) School of Medicine University of Minho, Campus de Gualtar, 4710-057 Braga – Portugal, Tel: +351253604827; E-mail: longatto16@hotmail.com or longatto@ med.uminho.pt
目标:巴西通过其统一卫生系统(SUS)向所有公民提供普遍、完整和免费的医疗保健。在巴西,圣保罗州拥有最复杂的医疗网络,根据SUS的指导方针,最接近于提供全面的医疗保健。然而,该系统的制约因素包括基本医疗保健网络和专科门诊诊所之间缺乏整合和协调,这既阻碍了适当获得专科服务,也阻碍了恢复基本保健。这种低效率助长了恶性循环,导致专科护理的等待时间超过两年。方法:在这篇文章中,我们描述了在巴西圣保罗巴雷托斯县的专科和初级保健之间逐步实施的制度和矩阵支持系统。结果:这种协调和整合的初步结果证明了可行性和良好的效果,如减少转诊到专科诊所的需求高达87%。结论:基质支持在提高医疗服务质量的同时,具有降低成本的潜力。*通讯:Adhemar longato - filho博士,巴雷托斯肿瘤医院分子肿瘤研究中心/Pio XII基金会,巴西,外科科学研究领域生命与健康科学研究所(ICVS)米尼奥大学医学院,瓜达尔校区,4710-057布拉加-葡萄牙,电话:+351253604827;电子邮件:longatto16@hotmail.com或longatto@ med.uminho.pt
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引用次数: 0
The in vitro Effects of Tryptamine, Harmine, and Harmaline on Leishmania tarentolae and the Possible Implications for Leishmaniasis 色胺、毒碱和毒碱对利什曼虫的体外作用及其对利什曼病的可能影响
IF 1.6 4区 医学 Q2 Nursing Pub Date : 2019-01-01 DOI: 10.15761/hpc.1000171
Jessica L. Wickline, Alexis Broedlow, Benjamin M. Dorsey, Kirk Eichenberg, Marjorie A. Jones
Leishmaniasis is a disease caused by Leishmania parasitic protozoans affecting people in both the Eastern and Western Hemispheres. The secreted acid phosphatase enzymes (SAPs) are reported to play a critical role in infection by Leishmania. Thus, these enzymes are potential targets for Leishmania therapy. Tryptamines have various physiological effects and thus serve different purposes socially. Tryptamines are used in ritualistic ceremonies in countries where Leishmania cases are reported. In this work, tryptamine and two other indole derivatives, harmine and harmaline, were investigated. Harmine and harmaline were selected because of their presence in the biological materials used in some South American ritualistic ceremonies. We investigated the effects on axenic Leishmania tarentolae cell shape, motility, clumping, and viability as well as on the activity of secreted acid phosphatase (SAP) from L. tarentolae. An overall decrease in cell viability over a seven-day period and a small recovery in cell viability, only at lower concentrations of test compounds, were observed. These compounds were, in general, activators of L. tarentolae SAP activity. This is the first report of effects of these compounds on Leishmania secreted acid phosphatase activity in vitro. We speculate that those with Leishmania infections may be worsening their condition with the exposure to these compounds. *Correspondence to: Marjorie A Jones, Department of Chemistry, Illinois State University, Normal, IL 61790-4160, USA, E-mail: majone3@ilstu.edu
利什曼病是一种由利什曼原虫寄生原虫引起的疾病,影响东半球和西半球的人群。分泌的酸性磷酸酶(sap)据报道在利什曼原虫感染中起关键作用。因此,这些酶是利什曼原虫治疗的潜在靶点。色胺具有多种生理作用,因此具有不同的社会用途。在报告利什曼原虫病例的国家,在仪式仪式中使用色胺。在这项工作中,研究了色胺和另外两种吲哚衍生物,烟碱和烟碱。选择毒蜂碱和毒蜂碱是因为它们存在于一些南美仪式中使用的生物材料中。本实验研究了不同处理对无生源利什曼绦虫细胞形态、运动、结块、活力以及分泌酸性磷酸酶(SAP)活性的影响。观察到,在7天的时间内,细胞活力总体下降,只有在较低浓度的测试化合物下,细胞活力才有小幅恢复。这些化合物通常是L. tarentolae SAP活性的激活剂。这是首次报道这些化合物对利什曼原虫分泌的酸性磷酸酶活性的影响。我们推测,那些感染利什曼原虫的人可能会因接触这些化合物而恶化病情。*通讯作者:Marjorie A Jones,伊利诺伊州立大学化学系,伊利诺伊州61790-4160,美国,E-mail: majone3@ilstu.edu
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引用次数: 0
UKMStrokIT: A web-based educational package tool for longer-term care of stroke patients: a pilot randomized controlled trial UKMStrokIT:基于网络的卒中患者长期护理教育包工具:一项试点随机对照试验
IF 1.6 4区 医学 Q2 Nursing Pub Date : 2019-01-01 DOI: 10.15761/hpc.1000159
Z Maisarah, Nik Nur Amr, Chang Zn, Ahmad Tmj, M Reenjaniswari, A. Saharuddin, Aziz Na
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引用次数: 2
Usefulness of barrier function index based on water content and transepidermal water loss for evaluating efficacy of skin protective creams 基于水分含量和经皮失水的屏障功能指数评价护肤霜功效的有效性
IF 1.6 4区 医学 Q2 Nursing Pub Date : 2019-01-01 DOI: 10.15761/HPC.1000164
T. Kubota, Yukina Watanabe, Anna Takahashi, Aki Sekine
The functionality of skin protective creams containing a film forming agent for enhancing barrier function was evaluated from the viewpoint of skin roughness prevention. The subjects were 15 healthy adults (7 females) without skin disorders ranging in age from 21-24 years (mean 22.1 years). Three sites on the medial side of the left forearm were used for measurements; an untreated control where no cream was applied, a small area applied with skin protective cream containing barrier ingredients, and a small area applied with skin protective cream containing no barrier ingredients. After repeated tape stripping for 20 times, transepidermal water loss (TEWL) and water content in the stratum corneum (SC) after applying skin protective cream were determined over time in each subject. Barrier function index was calculated based on TEWL and water content in the SC, and used to evaluate the effects of the barrier ingredients. For the untreated control, the initial mean value obtained at 0 hours, and then 1, 2 and 3 hours after skin protective cream application were 0.79, 0.70, 0.65, and 0.62, respectively. Those values for areas applied with cream containing no barrier ingredients were 0.42, 0.44, 0.43, and 0.41, respectively, while they were 0.39, 0.42, 0.39, and 0.40, respectively, for the areas applied with cream containing barrier ingredients. That later group showed the lowest values at each measurement time. Notably, high efficacy was seen for the cream containing barrier ingredients from 0 to 2 hours after application. These findings indicate that barrier function index is useful for evaluating the efficacy of skin protective creams.
从防止皮肤粗糙的角度评价了含成膜剂的增强屏障功能护肤霜的功能。受试者为15名健康成人(7名女性),无皮肤疾病,年龄21-24岁(平均22.1岁)。左前臂内侧三个部位进行测量;一个未经处理的对照组,其中没有涂抹面霜,一个小区域涂抹了含有屏障成分的护肤霜,一个小区域涂抹了不含屏障成分的护肤霜。在重复剥离胶带20次后,随着时间的推移测定每位受试者使用护肤霜后经皮失水(TEWL)和角质层含水量(SC)。基于土壤水分流失和土壤含水量计算屏障功能指数,评价屏障成分的作用。对于未处理的对照组,使用护肤霜后0小时、1小时、2小时和3小时的初始平均值分别为0.79、0.70、0.65和0.62。使用不含阻隔成分的面霜时,这些值分别为0.42、0.44、0.43和0.41,而使用含有阻隔成分的面霜时,这些值分别为0.39、0.42、0.39和0.40。后一组在每个测量时间都显示出最低的值。值得注意的是,在使用后0至2小时内,含有屏障成分的乳霜的疗效很高。这些结果表明,屏障功能指数可用于评价护肤霜的功效。
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引用次数: 0
Hughes-Stovin Syndrome or Vascular Behçet’s Disease? 休斯-斯托文综合征还是血管性脑血管病?
IF 1.6 4区 医学 Q2 Nursing Pub Date : 2019-01-01 DOI: 10.15761/hpc.1000173
S. Dumitru, A. Dragomir, F. Mihălțan
Hughes-Stovin Syndrome is a very rare pathology of unknown etiology with a lethal potential. It is characterized by the association of pulmonary artery aneurysms and peripheral venous thrombosis. We report the case of a 33 years old man with no prior illnesses, who came in for hemoptysis in small quantities. Based on the clinical presentation, the radiological studies and the histopathological finding we made our diagnosis of Hughes-Stovin Syndrome. The response to treatment was very good and at the 12 months follow-up the patient was completely asymptomatic, with no new radiological lessions on chest CT. *Correspondence to: Silviu-Mihail Dumitru MD, Marius Nasta, National Institute of Pneumophtisiology, Romania, E-mail: Dumitrusm@gmail.com
休斯-斯托文综合征是一种非常罕见的病因不明的病理,具有致命的潜在危险。它的特点是肺动脉动脉瘤和周围静脉血栓形成的关联。我们报告的情况下,33岁的男子,以前没有疾病,谁来了,在少量咯血。根据临床表现,放射学研究和组织病理学发现,我们诊断为休斯-斯托文综合征。治疗效果非常好,随访12个月,患者完全无症状,胸部CT无新的影像学表现。*通讯:罗马尼亚国家肺病研究所,Marius Nasta, Silviu-Mihail Dumitru医学博士,E-mail: Dumitrusm@gmail.com
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引用次数: 0
Should our practice participate in the New CMS Primary Care First Initiative? 我们的诊所是否应该参与新的CMS初级保健优先倡议?
IF 1.6 4区 医学 Q2 Nursing Pub Date : 2019-01-01 DOI: 10.15761/hpc.1000167
Mikila Lawless
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引用次数: 0
Alzheimer’s Disease: potential benefits of curcumin 阿尔茨海默病:姜黄素的潜在益处
IF 1.6 4区 医学 Q2 Nursing Pub Date : 2019-01-01 DOI: 10.15761/hpc.1000170
James W. Anderson
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引用次数: 0
Development of a patient-centred model of community-based OPAT (CoPAT) service in Singapore 在新加坡建立以患者为中心的社区OPAT服务模式
IF 1.6 4区 医学 Q2 Nursing Pub Date : 2019-01-01 DOI: 10.15761/hpc.1000169
Xu Yi, Lim Su Fee, F. Aloweni, Chua Ying Ying, H. Ying
There is a growing trend of expanding Outpatient Parenteral Antibiotics Therapy (OPAT) services to the community as it is more cost-effective for both patients and healthcare organisations. At the Singapore General Hospital (SGH), frail patients requiring intravenous (IV) antibiotics often have to prolong their hospitalisation to complete the course of treatment. Community OPAT (CoPAT) service is a joint effort between SGH Community Nursing and Department of Infectious Diseases. With the new CoPAT service, patients have the options of receiving their IV antibiotics at home rather than receiving treatment at the hospital or outpatient clinic. This case study described the process of providing CoPAT services in the community, its challenges and learning points and the positive outcomes of cost saving and improved patient experience. Early preliminary screening of suitable patients and good communication link among hospitals and community teams are essential in ensuring its success. *Correspondence to: Xu Yi, Senior Nurse Clinician (Community Nurse), RHSCommunity Nursing, Singapore General Hospital, Singapore, E-mail: xu.yi@ sgh.com.sg Received: August 27, 2019; Accepted: September 09, 2019; Published: September 12, 2019 Introduction Outpatient Parenteral Antibiotic Therapy (OPAT) refers to the approach for delivering intravenous (IV) antimicrobials in the outpatient setting or community [1]. OPAT service was first described in the United States in 1974 and was subsequently introduced to Singapore in 2002 [2]. This service requires a multidisciplinary team with expertise and experience in antimicrobial therapy for safety and long-term sustainability [3]. It is further recommended that the OPAT team provides an extension of services including laboratory testing, catheter care, regular nursing and physician assessments, follow-up, and adjustments as part of the optimal care to the existing primary illness, comorbidities and emerging complications [2]. Globally, there is a growing trend of expanding OPAT services to the community as it is cost-effective, and it also provides greater comfort to the patient when he/she receives the IV antibiotic at home [4]. OPAT improves patient’s satisfaction as it provides him/her the advantages of being able to resume his/her daily activities and having greater freedom and control at a familiar environment [5]. In additon, administering IV antibiotic at home reduces the risk of nosocomial complications as a result of prolonged hospitalisation [4]. In Singapore, OPAT services are mainly provided at specific outpatient clinics within acute hospitals. This service may not be accessible to patients who are frail or with limited mobility as it requires them to travel daily to the outpatient clinic and also incurs transportation costs. As a result, many of them would prefer to remain in the hospital till they receive the full course of IV antibiotics. This paper aims to describe the development of a patient-centred model o
扩大门诊静脉注射抗生素治疗(OPAT)服务到社区的趋势日益增长,因为它对患者和医疗机构都更具成本效益。在新加坡总医院(SGH),需要静脉注射(IV)抗生素的虚弱患者往往不得不延长住院时间以完成疗程。社区OPAT (CoPAT)服务是SGH社区护理和传染病科的共同努力。有了新的CoPAT服务,患者可以选择在家中接受静脉注射抗生素,而不是在医院或门诊接受治疗。本案例研究描述了在社区提供CoPAT服务的过程、挑战和学习点,以及节省成本和改善患者体验的积极成果。早期初步筛选合适的病人以及医院和社区团队之间良好的沟通联系是确保其成功的关键。*通讯:徐毅,高级护士临床医师(社区护士),RHSCommunity Nursing, Singapore General Hospital, Singapore, E-mail: Xu。收稿日期:2019年8月27日;录用日期:2019年9月9日;门诊静脉注射抗生素治疗(OPAT)是指在门诊或社区提供静脉注射(IV)抗菌药物的方法[1]。OPAT服务于1974年在美国首次被描述,随后于2002年被引入新加坡[2]。这项服务需要一个多学科的团队,在抗菌治疗方面具有专业知识和经验,以确保安全性和长期可持续性[3]。进一步建议OPAT团队提供延伸服务,包括实验室检测、导管护理、常规护理和医生评估、随访和调整,作为对现有原发疾病、合并症和新出现的并发症的最佳护理的一部分[2]。在全球范围内,将OPAT服务扩展到社区的趋势日益增长,因为它具有成本效益,并且当患者在家中接受静脉注射抗生素时,它也为患者提供了更大的舒适感[4]。OPAT提高了患者的满意度,因为它为患者提供了能够在熟悉的环境中恢复日常活动,拥有更大自由和控制的优势[5]。此外,在家中静脉注射抗生素可减少因长期住院而导致的院内并发症的风险[4]。在新加坡,OPAT服务主要在急症医院的特定门诊诊所提供。身体虚弱或行动不便的患者可能无法获得这项服务,因为这项服务要求他们每天前往门诊诊所,而且还需要支付交通费用。因此,他们中的许多人宁愿留在医院,直到他们接受了整个疗程的静脉注射抗生素。本文旨在通过案例研究方法描述以患者为中心的新加坡社区OPAT (CoPAT)服务模式的发展。
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引用次数: 0
Social representations and food practices of people with Diabetes Mellitus Type 2 2型糖尿病患者的社会表征与饮食习惯
IF 1.6 4区 医学 Q2 Nursing Pub Date : 2019-01-01 DOI: 10.15761/HPC.1000162
M. Amorim, Alessandra Hugo de Souza, N. Ramos, Maria Flávia Gazzinelli
1Researcher, Center for Studies of Migration and Intercultural Relations, Lisbon, Portugal 2Nutricionist Specialist in Geriatric Nutrition, Master student in the Graduate Program in Vertebrate Biology-PUC Minas, Brazil 3Professor, Open University of Lisbon, Center for Studies of Migration and Intercultural Relations, Lisbon, Portugal 4Professor, The School of Nursing at Federal University of Minas Gerais, Belo Horizonte, Brazil
1 .移民与跨文化关系研究中心研究员,葡萄牙里斯本2 .营养学家,老年营养学专家,脊椎动物生物学研究生课程硕士研究生,巴西米纳斯吉拉斯州puc米纳斯3 .里斯本开放大学教授,移民与跨文化关系研究中心,葡萄牙里斯本4 .米纳斯吉拉斯州联邦大学护理学院教授,巴西贝洛奥里藏特
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引用次数: 0
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Primary Health Care Research and Development
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