首页 > 最新文献

Journal of Global Health最新文献

英文 中文
Willingness of medical students to work on the COVID-19 frontline during the pandemic in China: A nationwide population-based cross-sectional study. 医学生是否愿意在中国 COVID-19 大流行期间到前线工作:一项基于全国人口的横断面研究。
IF 4.5 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-20 DOI: 10.7189/jogh.14.05034
Yuehui Jia, Yunfeng Han, Zhiping Xie, Xiaoting Chen, Wenting Li, Shuli Ma, Jun Wang, Jie Ge

Background: The World Health Organization declared that coronavirus disease 2019 (COVID-19) constitutes an international public health emergency, which has strained health resources. In this study, we aimed to understand medical students' willingness to join the workforce fighting against the COVID-19 pandemic and identify factors associated with their decisions.

Methods: We conducted a nationwide cross-sectional study using the Wen-Juan-Xing platform and a pre-designed questionnaire from 23 March to 19 April 2021. We conducted logistic regression analyses to identify the determinants associated with the willingness.

Results: Among the 5022 medical students, the majority (n = 4289, 85.40%) expressed willingness to work on the COVID-19 frontline. Logistic regression indicated that medical students' willingness to work on the COVID-19 frontline in China was associated with gender, region, reason for choosing medicine, having medical workers in the family, students whose family members, relatives or friends experienced COVID-19, and professional attitude. Females (odds ratio (OR) = 1.305; 95% confidence interval (CI) = 1.100-1.549; P = 0.0023), medical students from urban areas (OR = 1.295; 95% CI = 1.089-1.539; P = 0.0034), medical students whose choice of a medical career was their desire (OR = 1.579; 95% CI = 1.290-1.933; P < 0.0001), medical students whose parents or relatives are medical workers (OR = 1.266; 95% CI = 1.066-1.505; P = 0.0073), medical students whose family members, relatives, or friends have never been infected with COVID-19 (OR = 4.567; 95% CI = 3.002-6.947; P < 0.0001), and medical students with undisturbed of professional attitudes (OR = 4.280; 95% CI = 3.241-5.654; P < 0.0001) showed increased willingness to work on the COVID-19 frontline compared with their counterparts.

Conclusions: Medical students demonstrated a strong willingness to contribute to COVID-19 work during the pandemic in China. The findings may provide valuable information for emergency management so that policymakers can maintain sufficient health resources and provide quality health care in similar health emergencies in the future.

背景:世界卫生组织宣布,2019年冠状病毒病(COVID-19)已构成国际公共卫生紧急事件,导致卫生资源紧张。在本研究中,我们旨在了解医学生加入抗击 COVID-19 大流行工作队伍的意愿,并确定与他们的决定相关的因素:方法:2021 年 3 月 23 日至 4 月 19 日,我们利用文娟星平台和预先设计的问卷在全国范围内开展了一项横断面研究。我们进行了逻辑回归分析,以确定与意愿相关的决定因素:结果:在 5022 名医学生中,大多数(n = 4289,85.40%)表示愿意到 COVID-19 一线工作。逻辑回归表明,医学生到中国 COVID-19 一线工作的意愿与性别、地区、选择从医的原因、家庭中有医务工作者、家人或亲友经历过 COVID-19 的学生以及职业态度有关。女性(几率比(OR)=1.305;95% 置信区间(CI)=1.100-1.549;P=0.0023)、来自城市地区的医学生(OR=1.295;95% CI=1.089-1.539;P=0.0034)、选择医学职业是其愿望的医学生(OR=1.579;95% CI=1.290-1.933;P 结论:医学生在中国一线工作的意愿非常强烈:在中国大流行期间,医学生表现出了为 COVID-19 工作做出贡献的强烈意愿。研究结果可为应急管理提供有价值的信息,以便决策者在未来类似的突发卫生事件中保持足够的卫生资源并提供优质的医疗服务。
{"title":"Willingness of medical students to work on the COVID-19 frontline during the pandemic in China: A nationwide population-based cross-sectional study.","authors":"Yuehui Jia, Yunfeng Han, Zhiping Xie, Xiaoting Chen, Wenting Li, Shuli Ma, Jun Wang, Jie Ge","doi":"10.7189/jogh.14.05034","DOIUrl":"10.7189/jogh.14.05034","url":null,"abstract":"<p><strong>Background: </strong>The World Health Organization declared that coronavirus disease 2019 (COVID-19) constitutes an international public health emergency, which has strained health resources. In this study, we aimed to understand medical students' willingness to join the workforce fighting against the COVID-19 pandemic and identify factors associated with their decisions.</p><p><strong>Methods: </strong>We conducted a nationwide cross-sectional study using the Wen-Juan-Xing platform and a pre-designed questionnaire from 23 March to 19 April 2021. We conducted logistic regression analyses to identify the determinants associated with the willingness.</p><p><strong>Results: </strong>Among the 5022 medical students, the majority (n = 4289, 85.40%) expressed willingness to work on the COVID-19 frontline. Logistic regression indicated that medical students' willingness to work on the COVID-19 frontline in China was associated with gender, region, reason for choosing medicine, having medical workers in the family, students whose family members, relatives or friends experienced COVID-19, and professional attitude. Females (odds ratio (OR) = 1.305; 95% confidence interval (CI) = 1.100-1.549; P = 0.0023), medical students from urban areas (OR = 1.295; 95% CI = 1.089-1.539; P = 0.0034), medical students whose choice of a medical career was their desire (OR = 1.579; 95% CI = 1.290-1.933; P < 0.0001), medical students whose parents or relatives are medical workers (OR = 1.266; 95% CI = 1.066-1.505; P = 0.0073), medical students whose family members, relatives, or friends have never been infected with COVID-19 (OR = 4.567; 95% CI = 3.002-6.947; P < 0.0001), and medical students with undisturbed of professional attitudes (OR = 4.280; 95% CI = 3.241-5.654; P < 0.0001) showed increased willingness to work on the COVID-19 frontline compared with their counterparts.</p><p><strong>Conclusions: </strong>Medical students demonstrated a strong willingness to contribute to COVID-19 work during the pandemic in China. The findings may provide valuable information for emergency management so that policymakers can maintain sufficient health resources and provide quality health care in similar health emergencies in the future.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"14 ","pages":"05034"},"PeriodicalIF":4.5,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11658715/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142865941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A multi-phase structured cascade model for mass training of community healthcare workers in performing clinical breast exams in remote regions. 一个多阶段结构级联模型,用于在偏远地区进行临床乳房检查的社区卫生保健工作者的大规模培训。
IF 4.5 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-20 DOI: 10.7189/jogh.14.04255
Taleaa Masroor, Russell S Martins, Aiman Arif, Talaiha Chughtai, Falak Madhani, Nida Zahid, Sana Zeeshan, Lubna Vohra, Salima Khan, Mishal Hidayat, Hamna Amir, Sajid Bashir Soofi, Abida K Sattar

Background: Clinical breast exam (CBE) by outreach healthcare workers (HCW) may help downstage breast cancer in resource-limited areas where mammography may not be feasible. We evaluated the effectiveness of a pilot cascade-model training programme for HCWs in remote areas of Pakistan.

Methods: The training programme comprised three phases. In phase one, fellowship-trained breast surgeons at a metropolitan academic centre trained six HCWs to perform CBEs. In phase two, these six HCWs (master trainers) trained 15 additional HCWs, implementing cascade training. In phase three, the consultant breast surgeon conducted a re-evaluation and refresher course for all 21 HCWs at least one year after the original training session. We assessed CBE ability and skills through pre- and post-changes through self-reported confidence and direct observation of procedural skills.

Results: Significant improvements in learners' self-reported confidence and CBE skills were observed in both phases one and two. The median scores in the learners' post-training self-reported confidence and CBE skills (inspection, palpation, and lymph node examination) improved by 20% and 46.2%, respectively, indicating excellent learning outcomes of the cascade training sessions. Phase three showed sustained high scores in self-reported confidence and CBE skills more than one year later.

Conclusions: Mass training of outreach HCWs in remote regions in performing CBE may be possible with a structured multiphase cascade-training model and may be an important step in downstaging symptomatic breast cancer in low-resource settings.

背景:外展医疗工作者(HCW)进行临床乳房检查(CBE)可帮助资源有限的地区降低乳腺癌的分期,因为这些地区可能无法进行乳房X光检查。我们评估了针对巴基斯坦偏远地区医护人员的试点级联模式培训计划的有效性:培训计划包括三个阶段。在第一阶段,由一个大都市学术中心受过研究员培训的乳腺外科医生对六名医护人员进行 CBE 培训。在第二阶段,这六名医护人员(主培训师)又培训了 15 名医护人员,实施逐级培训。在第三阶段,乳腺外科医生顾问在最初的培训课程结束至少一年后对所有 21 名医护人员进行了重新评估和复习课程。我们通过自我信心报告和直接观察手术技能来评估 CBE 能力和技能的前后变化:在第一和第二阶段,学员自报的信心和 CBE 技能均有显著提高。学员在培训后自我报告的自信心和 CBE 技能(检查、触诊和淋巴结检查)的中位数分别提高了 20% 和 46.2%,表明串联培训课程取得了良好的学习效果。第三阶段显示,一年多后,自我报告的信心和 CBE 技能持续保持高分:结论:通过结构化的多阶段串联培训模式,可以对偏远地区的外展医护人员进行大规模的CBE培训,这可能是在低资源环境下对无症状乳腺癌进行分期的重要一步。
{"title":"A multi-phase structured cascade model for mass training of community healthcare workers in performing clinical breast exams in remote regions.","authors":"Taleaa Masroor, Russell S Martins, Aiman Arif, Talaiha Chughtai, Falak Madhani, Nida Zahid, Sana Zeeshan, Lubna Vohra, Salima Khan, Mishal Hidayat, Hamna Amir, Sajid Bashir Soofi, Abida K Sattar","doi":"10.7189/jogh.14.04255","DOIUrl":"10.7189/jogh.14.04255","url":null,"abstract":"<p><strong>Background: </strong>Clinical breast exam (CBE) by outreach healthcare workers (HCW) may help downstage breast cancer in resource-limited areas where mammography may not be feasible. We evaluated the effectiveness of a pilot cascade-model training programme for HCWs in remote areas of Pakistan.</p><p><strong>Methods: </strong>The training programme comprised three phases. In phase one, fellowship-trained breast surgeons at a metropolitan academic centre trained six HCWs to perform CBEs. In phase two, these six HCWs (master trainers) trained 15 additional HCWs, implementing cascade training. In phase three, the consultant breast surgeon conducted a re-evaluation and refresher course for all 21 HCWs at least one year after the original training session. We assessed CBE ability and skills through pre- and post-changes through self-reported confidence and direct observation of procedural skills.</p><p><strong>Results: </strong>Significant improvements in learners' self-reported confidence and CBE skills were observed in both phases one and two. The median scores in the learners' post-training self-reported confidence and CBE skills (inspection, palpation, and lymph node examination) improved by 20% and 46.2%, respectively, indicating excellent learning outcomes of the cascade training sessions. Phase three showed sustained high scores in self-reported confidence and CBE skills more than one year later.</p><p><strong>Conclusions: </strong>Mass training of outreach HCWs in remote regions in performing CBE may be possible with a structured multiphase cascade-training model and may be an important step in downstaging symptomatic breast cancer in low-resource settings.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"14 ","pages":"04255"},"PeriodicalIF":4.5,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11659790/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142865857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Do nutritional interventions before or during pregnancy affect placental phenotype? Findings from a systematic review of human clinical trials. 孕前或孕期的营养干预会影响胎盘表型吗?一项人体临床试验系统综述的发现。
IF 4.5 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-20 DOI: 10.7189/jogh.14.04240
Victoria Bonnell, Marina White, Kristin Connor
<p><strong>Background: </strong>Maternal nutritional interventions aim to address nutrient deficiencies in pregnancy, a leading cause of maternal and neonatal morbidity and mortality worldwide. How these interventions influence the placenta, which plays a vital role in fetal growth and nutrient supply, is not well understood. This leaves a major gap in understanding how such interventions could influence pregnancy outcomes and fetal health. We hypothesised that nutritional interventions influence placental phenotype, and that these placental changes relate to how successful an intervention is in improving pregnancy outcomes.</p><p><strong>Methods: </strong>We searched PubMed, ClinicalTrials.gov, and the World Health Organization (WHO) International Clinical Trials Registry Platform using pre-defined search terms for records published from January 2001 to September 2021 that reported on clinical trials in humans, which administered a maternal nutritional intervention during the periconceptional or pregnancy period and reported on placental phenotype (shape and form, function or placental disorders). These records were then screened by two reviewers for eligibility.</p><p><strong>Results: </strong>Fifty-three eligible articles reported on (multiple) micronutrient- (n = 33 studies), lipid- (n = 11), protein- (n = 2), and diet-/lifestyle-based (n = 8) interventions. Of the micronutrient-based interventions, 16 (48%) were associated with altered placental function, namely altered nutrient transport/metabolism (n = 9). Nine (82%) of the lipid-based interventions were associated with altered placental phenotype, including elevated placental fatty acid levels (n = 5), altered nutrient transport/metabolism gene expression (n = 4), and decreased inflammatory biomarkers (n = 2). Of the protein-based interventions, two (66%) were associated with altered placental phenotype, including increased placental efficiency (n = 1) and decreased preeclampsia risk (n = 1). Three (38%) of diet and lifestyle-based interventions were associated with placental changes, namely placental gene expression (n = 1) and disease (n = 2). In studies with data on maternal (n = 30) or offspring (n = 20) outcomes, interventions that influenced placental phenotype were more likely to have also been associated with improved maternal outcomes (n/N = 11/15, 73%) and offspring birth outcomes (n/N = 6/11, 54%) compared to interventions that did not associate with placental changes (n/N = 2/15 (13%) and n/N = 1/9 (11%) respectively).</p><p><strong>Conclusions: </strong>Periconceptional and prenatal nutritional interventions to improve maternal/pregnancy health associate with altered placental development and function. These placental adaptations likely benefit the pregnancy and improve offspring outcomes. Understanding the placenta's role in the success of interventions to combat nutrient deficiencies is critical for improving interventions and reducing maternal and neonatal morbidity and mo
背景:孕产妇营养干预旨在解决妊娠期营养缺乏问题,这是导致全球孕产妇和新生儿发病和死亡的主要原因。胎盘在胎儿生长和营养供应中发挥着至关重要的作用,但人们对这些干预措施如何影响胎盘还不甚了解。这为了解这些干预措施如何影响妊娠结局和胎儿健康留下了重大空白。我们假设营养干预会影响胎盘表型,而胎盘的这些变化与干预在改善妊娠结局方面的成功程度有关:我们使用预先定义的检索词检索了 PubMed、ClinicalTrials.gov 和世界卫生组织(WHO)国际临床试验注册平台上 2001 年 1 月至 2021 年 9 月期间发表的有关人类临床试验的记录,这些临床试验在围孕期或妊娠期实施了母体营养干预,并报告了胎盘表型(形状和形态、功能或胎盘疾病)。然后由两名审稿人对这些记录进行资格筛选:53篇符合条件的文章报告了(多项)基于微量营养素(33项研究)、脂质(11项)、蛋白质(2项)和饮食/生活方式(8项)的干预措施。在以微量营养素为基础的干预中,16 项(48%)与胎盘功能改变有关,即营养素转运/代谢改变(9 项)。9项(82%)基于脂质的干预措施与胎盘表型的改变有关,包括胎盘脂肪酸水平升高(5人)、营养素转运/代谢基因表达改变(4人)和炎症生物标志物减少(2人)。在以蛋白质为基础的干预措施中,有两项(66%)与胎盘表型的改变有关,包括提高胎盘效率(1 例)和降低子痫前期风险(1 例)。三项(38%)基于饮食和生活方式的干预措施与胎盘变化有关,即胎盘基因表达(n = 1)和疾病(n = 2)。在有孕产妇(n = 30)或后代(n = 20)结局数据的研究中,与不涉及胎盘变化的干预措施(分别为 n/N = 2/15 (13%) 和 n/N = 1/9 (11%))相比,影响胎盘表型的干预措施更有可能同时改善孕产妇结局(n/N = 11/15,73%)和后代出生结局(n/N = 6/11,54%):结论:为改善孕产妇健康状况而采取的围孕期和产前营养干预措施会改变胎盘的发育和功能。这些胎盘适应性可能有利于妊娠并改善后代的预后。了解胎盘在成功干预营养缺乏症方面的作用,对于改进干预措施、降低全球孕产妇和新生儿发病率和死亡率至关重要。
{"title":"Do nutritional interventions before or during pregnancy affect placental phenotype? Findings from a systematic review of human clinical trials.","authors":"Victoria Bonnell, Marina White, Kristin Connor","doi":"10.7189/jogh.14.04240","DOIUrl":"10.7189/jogh.14.04240","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Maternal nutritional interventions aim to address nutrient deficiencies in pregnancy, a leading cause of maternal and neonatal morbidity and mortality worldwide. How these interventions influence the placenta, which plays a vital role in fetal growth and nutrient supply, is not well understood. This leaves a major gap in understanding how such interventions could influence pregnancy outcomes and fetal health. We hypothesised that nutritional interventions influence placental phenotype, and that these placental changes relate to how successful an intervention is in improving pregnancy outcomes.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We searched PubMed, ClinicalTrials.gov, and the World Health Organization (WHO) International Clinical Trials Registry Platform using pre-defined search terms for records published from January 2001 to September 2021 that reported on clinical trials in humans, which administered a maternal nutritional intervention during the periconceptional or pregnancy period and reported on placental phenotype (shape and form, function or placental disorders). These records were then screened by two reviewers for eligibility.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Fifty-three eligible articles reported on (multiple) micronutrient- (n = 33 studies), lipid- (n = 11), protein- (n = 2), and diet-/lifestyle-based (n = 8) interventions. Of the micronutrient-based interventions, 16 (48%) were associated with altered placental function, namely altered nutrient transport/metabolism (n = 9). Nine (82%) of the lipid-based interventions were associated with altered placental phenotype, including elevated placental fatty acid levels (n = 5), altered nutrient transport/metabolism gene expression (n = 4), and decreased inflammatory biomarkers (n = 2). Of the protein-based interventions, two (66%) were associated with altered placental phenotype, including increased placental efficiency (n = 1) and decreased preeclampsia risk (n = 1). Three (38%) of diet and lifestyle-based interventions were associated with placental changes, namely placental gene expression (n = 1) and disease (n = 2). In studies with data on maternal (n = 30) or offspring (n = 20) outcomes, interventions that influenced placental phenotype were more likely to have also been associated with improved maternal outcomes (n/N = 11/15, 73%) and offspring birth outcomes (n/N = 6/11, 54%) compared to interventions that did not associate with placental changes (n/N = 2/15 (13%) and n/N = 1/9 (11%) respectively).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Periconceptional and prenatal nutritional interventions to improve maternal/pregnancy health associate with altered placental development and function. These placental adaptations likely benefit the pregnancy and improve offspring outcomes. Understanding the placenta's role in the success of interventions to combat nutrient deficiencies is critical for improving interventions and reducing maternal and neonatal morbidity and mo","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"14 ","pages":"04240"},"PeriodicalIF":4.5,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11658718/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142865873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum: Maffioli EM, Montás MC, Anyakora C. Excessive active pharmaceutical ingredients in substandard and falsified drugs should also raise concerns in low-income countries. J Glob Health. 2024 Jun 7;14:03029. 更正:Maffioli EM, Montás MC, Anyakora C.不合格和伪造药品中过量的活性药物成分也应引起低收入国家的关注。[J]全球健康。2024年6月7日;14:03029。
IF 4.5 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-20 DOI: 10.7189/jogh.14.1403029err1

This corrects the article DOI: 10.7189/jogh.14.03029.

这更正了文章DOI: 10.7189/ john .14.03029。
{"title":"Erratum: Maffioli EM, Montás MC, Anyakora C. Excessive active pharmaceutical ingredients in substandard and falsified drugs should also raise concerns in low-income countries. J Glob Health. 2024 Jun 7;14:03029.","authors":"","doi":"10.7189/jogh.14.1403029err1","DOIUrl":"10.7189/jogh.14.1403029err1","url":null,"abstract":"<p><p>This corrects the article DOI: 10.7189/jogh.14.03029.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"14 ","pages":"1403029err1"},"PeriodicalIF":4.5,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11698239/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142865800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Redefining health priorities: Sub-Saharan Africa's new frontier in disease burden. 重新确定卫生重点:撒哈拉以南非洲在疾病负担方面的新前沿。
IF 4.5 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-20 DOI: 10.7189/jogh.14.03049
Taddese A Zerfu, Amare A Tareke, Sibhatu Biadgilign
{"title":"Redefining health priorities: Sub-Saharan Africa's new frontier in disease burden.","authors":"Taddese A Zerfu, Amare A Tareke, Sibhatu Biadgilign","doi":"10.7189/jogh.14.03049","DOIUrl":"10.7189/jogh.14.03049","url":null,"abstract":"","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"14 ","pages":"03049"},"PeriodicalIF":4.5,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11660012/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142865926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of COVID-19 on the utilisation of maternal and child health services in Peru at national and subnational levels: An interrupted time series analysis. 2019冠状病毒病对秘鲁国家和国家以下各级妇幼保健服务利用的影响:一项中断时间序列分析。
IF 4.5 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-20 DOI: 10.7189/jogh.14.05039
Luis Huicho, Carlos A Huayanay-Espinoza, Rodrigo Valladares, Alvaro G Oviedo-Rios, Soleda S Ruiz-Lopez, Nadia Akseer, Abdoulaye Maïga, Alicia Matijasevich, Agbessi Amouzou

Background: The resilience of Peru´s health system was weakened by a political crisis that started in 2016 and was further challenged by the coronavirus 2019 (COVID-19) pandemic. We assessed the indirect impact of the pandemic on the utilisation of essential maternal and child health (MCH) services in Peru at national and subnational levels.

Methods: We assessed the trends in MCH services utilisation and the percentage change from 2018 to 2021, using routine health facility data. We used an interrupted time series analysis to quantify the impact of COVID-19 on the utilisation of health services.

Results: The utilisation of most maternal and child health services dropped dramatically in 2020 after the outbreak. However, we observed a quick recovery in 2021, with service utilisation fairly similar or higher to the pre-pandemic period (2018-2019). The decrease was higher in the utilisation of antenatal care visit one or more (incidence rate ratio (IRR) = 0.79; 95% CI = 0.74-0.83) and antenatal care visits four or more (IRR= 0.76; 95% = 0.74-0.79) in 2020. The IRR showed a drop of 5, 6, 9, and 13% in the utilisation of skilled birth attendances, institutional deliveries, caesarean sections and postnatal care visits within two days of childbirth, respectively in 2020 in comparison to pre-pandemic service utilisation. In 2020 the utilisation decreased in all three natural regions, with the Rainforest being the most affected. In 2021 there was a recovery in all natural regions.

Conclusions: The pandemic decreased the utilisation of essential maternal and child health services in Peru. This highlights the need to preserve the resilience of a health system both at central and local levels, to face more successfully future pandemics.

背景:秘鲁卫生系统的复原力因2016年开始的政治危机而受到削弱,并因2019年冠状病毒(COVID-19)大流行而进一步受到挑战。我们评估了疫情对秘鲁国家和国家以下各级基本妇幼保健(MCH)服务利用率的间接影响:我们使用常规医疗机构数据评估了妇幼保健服务利用率的趋势以及 2018 年至 2021 年的百分比变化。我们使用间断时间序列分析来量化 COVID-19 对医疗服务利用率的影响:结果:疫情爆发后,大多数妇幼保健服务的利用率在 2020 年急剧下降。然而,我们观察到 2021 年疫情迅速恢复,服务利用率与疫情爆发前(2018-2019 年)相当或更高。2020 年,一次或多次产前检查(发病率比(IRR)= 0.79;95% CI = 0.74-0.83)和四次或多次产前检查(IRR= 0.76;95% = 0.74-0.79)的使用率下降幅度较大。与流行前相比,2020 年熟练助产士接生、住院分娩、剖腹产和产后两天内产后护理的使用率分别下降了 5%、6%、9% 和 13%。2020 年,所有三个自然区的服务利用率都有所下降,其中雨林地区受到的影响最大。2021 年,所有自然区的利用率都有所恢复:大流行降低了秘鲁基本妇幼保健服务的利用率。这突出表明,有必要在中央和地方各级保持卫生系统的复原力,以便更成功地面对未来的大流行病。
{"title":"Impact of COVID-19 on the utilisation of maternal and child health services in Peru at national and subnational levels: An interrupted time series analysis.","authors":"Luis Huicho, Carlos A Huayanay-Espinoza, Rodrigo Valladares, Alvaro G Oviedo-Rios, Soleda S Ruiz-Lopez, Nadia Akseer, Abdoulaye Maïga, Alicia Matijasevich, Agbessi Amouzou","doi":"10.7189/jogh.14.05039","DOIUrl":"10.7189/jogh.14.05039","url":null,"abstract":"<p><strong>Background: </strong>The resilience of Peru´s health system was weakened by a political crisis that started in 2016 and was further challenged by the coronavirus 2019 (COVID-19) pandemic. We assessed the indirect impact of the pandemic on the utilisation of essential maternal and child health (MCH) services in Peru at national and subnational levels.</p><p><strong>Methods: </strong>We assessed the trends in MCH services utilisation and the percentage change from 2018 to 2021, using routine health facility data. We used an interrupted time series analysis to quantify the impact of COVID-19 on the utilisation of health services.</p><p><strong>Results: </strong>The utilisation of most maternal and child health services dropped dramatically in 2020 after the outbreak. However, we observed a quick recovery in 2021, with service utilisation fairly similar or higher to the pre-pandemic period (2018-2019). The decrease was higher in the utilisation of antenatal care visit one or more (incidence rate ratio (IRR) = 0.79; 95% CI = 0.74-0.83) and antenatal care visits four or more (IRR= 0.76; 95% = 0.74-0.79) in 2020. The IRR showed a drop of 5, 6, 9, and 13% in the utilisation of skilled birth attendances, institutional deliveries, caesarean sections and postnatal care visits within two days of childbirth, respectively in 2020 in comparison to pre-pandemic service utilisation. In 2020 the utilisation decreased in all three natural regions, with the Rainforest being the most affected. In 2021 there was a recovery in all natural regions.</p><p><strong>Conclusions: </strong>The pandemic decreased the utilisation of essential maternal and child health services in Peru. This highlights the need to preserve the resilience of a health system both at central and local levels, to face more successfully future pandemics.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"14 ","pages":"05039"},"PeriodicalIF":4.5,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11659789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142865920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of the COVID-19 pandemic on maternal, newborn, and child health service coverage in Burkina Faso. COVID-19 大流行对布基纳法索孕产妇、新生儿和儿童保健服务覆盖面的影响。
IF 4.5 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-20 DOI: 10.7189/jogh.14.05037
Abdoulaye Maïga, Moussa Bougma, Emily Wilson, Théodore S Kaboré, Gildas G Tou, Melinda K Munos, Almamy M Kanté, Safia S Jiwani, Kelsey Zack, Aveika Akum, Neff Walker, Robert E Black, Agbessi Amouzou

Background: While countries' coronavirus disease 2019 (COVID-19) emergency contingency and response plans aimed to prevent and control the spread of the virus, they also caused major disruptions to health services. We assessed the effects of COVID-19 on coverage and inequalities in select maternal, newborn, and child health services in Burkina Faso.

Methods: We analysed data from two cross-sectional household surveys conducted in two provinces, one rural and one urban. The first survey of 3375 households was conducted immediately before the pandemic (February to March 2020) and the second survey in the same areas two years after the pandemic (May to June 2022) using a similar methodology. We compared the coverage of maternal, newborn, and child health interventions and care-seeking between the two surveys to assess the effects of the pandemic on maternal, newborn, and child health services.

Results: Our findings did not show significant disruptions in coverage of antenatal service, postnatal care for mothers and babies, child routine vaccination, and care-seeking for sick children during the pandemic. However, there was a dramatic drop of the number of women (23 percentage points) accompanied by their partners for delivery as well as the number of caesarean-section deliveries in urban areas. The shortage of health staff, facility congestion, fear of getting COVID-19 after a caesarean-section admission, and prioritisation of critical health services such as emergency caesarean-section to the detriment of elective cases may explain the decline of caesarean-section rates.

Conclusions: COVID-19 did not cause major reversals in the coverage of maternal, newborn, and child health services in Burkina Faso, except for caesarean sections. We also saw no substantial increases in service coverage. In the absence of a counterfactual, we could not attribute the stagnation to the pandemic. However, the very low proportion of women reporting disruption in care-seeking suggests some resilience of the health systems to mitigate the negative impacts of the pandemic.

背景:虽然各国的冠状病毒病 2019(COVID-19)紧急应急和响应计划旨在预防和控制病毒传播,但也对医疗服务造成了重大干扰。我们评估了 COVID-19 对布基纳法索特定孕产妇、新生儿和儿童保健服务覆盖率和不平等现象的影响:我们分析了在两个省(一个农村省和一个城市省)进行的两次横断面家庭调查的数据。第一次调查在疫情爆发前夕(2020 年 2 月至 3 月)进行,共调查了 3375 户家庭;第二次调查在疫情爆发两年后(2022 年 5 月至 6 月)在同一地区进行,采用了类似的方法。我们比较了两次调查中孕产妇、新生儿和儿童保健干预措施的覆盖范围以及寻求护理的情况,以评估大流行对孕产妇、新生儿和儿童保健服务的影响:结果:我们的调查结果显示,在大流行期间,产前服务、母婴产后护理、儿童常规疫苗接种和患病儿童寻求护理的覆盖率并没有出现明显的中断。然而,在城市地区,由伴侣陪伴分娩的妇女人数和剖腹产人数急剧下降(23 个百分点)。医护人员短缺、医疗机构拥挤、担心剖腹产后感染 COVID-19,以及优先考虑急诊剖腹产等关键医疗服务而忽视择期剖腹产,可能是剖腹产率下降的原因:除剖腹产外,COVID-19 并未导致布基纳法索孕产妇、新生儿和儿童保健服务覆盖率出现重大逆转。我们也没有看到服务覆盖率的大幅增长。在缺乏反事实的情况下,我们无法将这种停滞归咎于大流行病。然而,报告就医中断的妇女比例很低,这表明卫生系统具有一定的复原力,能够减轻大流行病的负面影响。
{"title":"Effects of the COVID-19 pandemic on maternal, newborn, and child health service coverage in Burkina Faso.","authors":"Abdoulaye Maïga, Moussa Bougma, Emily Wilson, Théodore S Kaboré, Gildas G Tou, Melinda K Munos, Almamy M Kanté, Safia S Jiwani, Kelsey Zack, Aveika Akum, Neff Walker, Robert E Black, Agbessi Amouzou","doi":"10.7189/jogh.14.05037","DOIUrl":"10.7189/jogh.14.05037","url":null,"abstract":"<p><strong>Background: </strong>While countries' coronavirus disease 2019 (COVID-19) emergency contingency and response plans aimed to prevent and control the spread of the virus, they also caused major disruptions to health services. We assessed the effects of COVID-19 on coverage and inequalities in select maternal, newborn, and child health services in Burkina Faso.</p><p><strong>Methods: </strong>We analysed data from two cross-sectional household surveys conducted in two provinces, one rural and one urban. The first survey of 3375 households was conducted immediately before the pandemic (February to March 2020) and the second survey in the same areas two years after the pandemic (May to June 2022) using a similar methodology. We compared the coverage of maternal, newborn, and child health interventions and care-seeking between the two surveys to assess the effects of the pandemic on maternal, newborn, and child health services.</p><p><strong>Results: </strong>Our findings did not show significant disruptions in coverage of antenatal service, postnatal care for mothers and babies, child routine vaccination, and care-seeking for sick children during the pandemic. However, there was a dramatic drop of the number of women (23 percentage points) accompanied by their partners for delivery as well as the number of caesarean-section deliveries in urban areas. The shortage of health staff, facility congestion, fear of getting COVID-19 after a caesarean-section admission, and prioritisation of critical health services such as emergency caesarean-section to the detriment of elective cases may explain the decline of caesarean-section rates.</p><p><strong>Conclusions: </strong>COVID-19 did not cause major reversals in the coverage of maternal, newborn, and child health services in Burkina Faso, except for caesarean sections. We also saw no substantial increases in service coverage. In the absence of a counterfactual, we could not attribute the stagnation to the pandemic. However, the very low proportion of women reporting disruption in care-seeking suggests some resilience of the health systems to mitigate the negative impacts of the pandemic.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"14 ","pages":"05037"},"PeriodicalIF":4.5,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11658717/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142865875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multimorbidity in elderly patients with or without T2DM: A real-world cross-sectional analysis based on primary care and hospitalisation data. 老年T2DM患者的多发病:基于初级保健和住院数据的真实世界横断面分析
IF 4.5 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-20 DOI: 10.7189/jogh.14.04263
Yang Li, Shasha Geng, Huixiao Yuan, Jianli Ge, Qingqing Li, Xin Chen, Yingqian Zhu, Yue Liu, Xiaotong Guo, Xiaoli Wang, Hua Jiang

Background: Shanghai's high level of ageing has given rise to a considerable number of elderly patients with type 2 diabetes mellitus (T2DM) who are confronted with the challenge of managing multimorbidity. We aimed to determine the prevalence of multimorbidity in elderly T2DM patients in a representative Pudong New Area community and critically evaluate current guidelines' inclusiveness in addressing major comorbidities.

Methods: Through the Shanghai Health Cloud platform, we extracted medical records of residents in the Huamu community (Pudong New Area, Shanghai) to screen elderly patients with at least three outpatient visits or one hospitalisation per year between 2019 and 2022. According to International Classification of Disease, 10th edition codes and personal identification number, we identified the status of T2DM and 12 other common chronic diseases, matched T2DM patients and non-T2DM patients 1:1 by age and gender, and then calculated the prevalence of multimorbidity status and annual prevalence of each comorbidity. We analysed associations between T2DM and specific chronic diseases using logistic regression models.

Results: More than 90% of elderly T2DM patients had at least one additional chronic disease. Multimorbidity was more frequent in women and older patients. Hyperlipidemia, hypertension, and ischaemic heart disease were the most prevalent comorbidities. The diagnosis of T2DM was significantly associated with both cardiovascular-kidney-metabolic and neuropsychiatric diseases. In addition, a higher prevalence and risk of chronic obstructive pulmonary disease (COPD) were consistently detected in elderly patients with T2DM, regardless of age and gender.

Conclusions: Multimorbidity in elderly patients with T2DM needs broader acknowledgement. Current guidelines focus more on cardiovascular-kidney-metabolic and neuropsychiatric diseases with inadequate guidance on COPD management. Hence, the pleiotropic effects of glucose-lowering drugs on COPD should be further investigated to optimise the comprehensive management strategy for this population.

背景:上海的高老龄化水平导致了相当数量的老年2型糖尿病(T2DM)患者面临着多病管理的挑战。我们旨在确定具有代表性的浦东新区社区老年T2DM患者的多病患病率,并批判性地评估当前指南在解决主要合并症方面的包容性。方法:通过上海健康云平台提取上海市浦东新区花木社区居民病历,对2019 - 2022年间每年至少门诊3次或住院1次的老年患者进行筛查。根据《国际疾病分类》第10版代码和个人识别码,我们确定T2DM和其他12种常见慢性疾病的状态,将T2DM患者和非T2DM患者按年龄和性别1:1匹配,然后计算出多种疾病状态的患病率和每种合并症的年患病率。我们使用逻辑回归模型分析了T2DM与特定慢性疾病之间的关系。结果:超过90%的老年T2DM患者至少有一种额外的慢性疾病。多病在女性和老年患者中更为常见。高脂血症、高血压和缺血性心脏病是最常见的合并症。T2DM的诊断与心血管-肾-代谢和神经精神疾病均有显著相关性。此外,在老年T2DM患者中,无论年龄和性别,慢性阻塞性肺疾病(COPD)的患病率和风险均较高。结论:老年T2DM患者的多发病需要更广泛的认识。目前的指南更多地关注心血管-肾-代谢和神经精神疾病,对COPD管理的指导不足。因此,应进一步研究降糖药物对慢性阻塞性肺病的多效作用,以优化针对该人群的综合管理策略。
{"title":"Multimorbidity in elderly patients with or without T2DM: A real-world cross-sectional analysis based on primary care and hospitalisation data.","authors":"Yang Li, Shasha Geng, Huixiao Yuan, Jianli Ge, Qingqing Li, Xin Chen, Yingqian Zhu, Yue Liu, Xiaotong Guo, Xiaoli Wang, Hua Jiang","doi":"10.7189/jogh.14.04263","DOIUrl":"10.7189/jogh.14.04263","url":null,"abstract":"<p><strong>Background: </strong>Shanghai's high level of ageing has given rise to a considerable number of elderly patients with type 2 diabetes mellitus (T2DM) who are confronted with the challenge of managing multimorbidity. We aimed to determine the prevalence of multimorbidity in elderly T2DM patients in a representative Pudong New Area community and critically evaluate current guidelines' inclusiveness in addressing major comorbidities.</p><p><strong>Methods: </strong>Through the Shanghai Health Cloud platform, we extracted medical records of residents in the Huamu community (Pudong New Area, Shanghai) to screen elderly patients with at least three outpatient visits or one hospitalisation per year between 2019 and 2022. According to International Classification of Disease, 10th edition codes and personal identification number, we identified the status of T2DM and 12 other common chronic diseases, matched T2DM patients and non-T2DM patients 1:1 by age and gender, and then calculated the prevalence of multimorbidity status and annual prevalence of each comorbidity. We analysed associations between T2DM and specific chronic diseases using logistic regression models.</p><p><strong>Results: </strong>More than 90% of elderly T2DM patients had at least one additional chronic disease. Multimorbidity was more frequent in women and older patients. Hyperlipidemia, hypertension, and ischaemic heart disease were the most prevalent comorbidities. The diagnosis of T2DM was significantly associated with both cardiovascular-kidney-metabolic and neuropsychiatric diseases. In addition, a higher prevalence and risk of chronic obstructive pulmonary disease (COPD) were consistently detected in elderly patients with T2DM, regardless of age and gender.</p><p><strong>Conclusions: </strong>Multimorbidity in elderly patients with T2DM needs broader acknowledgement. Current guidelines focus more on cardiovascular-kidney-metabolic and neuropsychiatric diseases with inadequate guidance on COPD management. Hence, the pleiotropic effects of glucose-lowering drugs on COPD should be further investigated to optimise the comprehensive management strategy for this population.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"14 ","pages":"04263"},"PeriodicalIF":4.5,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11658714/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142865922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Addressing barriers to global multidisciplinary stakeholder inclusivity: Lessons from global orofacial cleft research priority setting. 解决全球多学科利益相关者包容性的障碍:来自全球口腔腭裂研究优先设置的经验教训。
IF 4.5 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-13 DOI: 10.7189/jogh.14.04261
Niki Kouvroukoglou, Sanita Sandhu, Barbara Delage, Debbie Sell, Nicola Stock, Gareth Davies, Marina Campodonico, Bruce Richard, Zipporah Njeri Gathuya, Mekonen Eshete, Felicity V Mehendale

Background: Inclusivity in research priority setting is fundamental to capturing the opinion of all stakeholders in a research area. Globally, experienced healthcare workers often have deep insights that could impactfully shape future research, and a lack of their involvement in formal research and publications could mean that their voices are insufficiently represented. We aimed to modify the well-established Child Health and Nutrition Research Initiative (CHNRI) methodology to address barriers to inclusivity, which are particularly relevant in healthcare that requires highly multidisciplinary care.

Methods: This global research priority-setting exercise for orofacial clefts adapted the CHNRI methodology to include research experts, clinicians from multiple disciplines, and non-technical stakeholders (i.e. patients and parents and non-governmental organisations (NGOs)) on a global basis. A multidisciplinary international steering group proposed and discussed methodological changes to improve inclusivity, including survey edits, subgroups for research questions, a demographics section, translation in French and Spanish, phrasing adaptation, and alternative dissemination techniques.

Results: We received 412 responses and 1420 questions, spanning 78 different countries and 18 different specialties/groups. Challenges remain to improve representation of all groups, with the vast majority of answers (30%) being from surgeons and a comparatively small proportion from patient/parent groups (9%). This also includes managing responses in three languages, effective dissemination, and responses that were not worded as research questions.

Conclusions: This is one of the first CHNRI exercises to involve patients and parents, clinicians, and researchers in its first question submission stage, and the first ever to do so on a global scale. We describe our approach to addressing inclusivity challenges and report related demographic data to serve as a benchmark upon which we hope future CHNRI exercises will improve.

背景:在确定研究重点的过程中,包容性是获取研究领域所有利益相关者意见的基础。在全球范围内,经验丰富的医护人员往往具有深刻的见解,能够对未来的研究产生影响,而他们在正式研究和出版物中的参与度不足可能意味着他们的意见没有得到充分反映。我们旨在修改行之有效的儿童健康与营养研究计划(CHNRI)方法,以解决包容性方面的障碍,这些障碍在需要高度多学科护理的医疗保健领域尤为重要:方法:这项针对口面裂隙的全球研究优先事项制定工作对 CHNRI 方法进行了调整,在全球范围内纳入了研究专家、多学科临床医生和非技术利益相关者(即患者和家长以及非政府组织 (NGO))。一个多学科国际指导小组提出并讨论了方法上的改变,以提高包容性,包括调查编辑、研究问题分组、人口统计部分、法文和西班牙文翻译、措辞调整和其他传播技术:我们收到了 412 份回复和 1420 个问题,涉及 78 个不同国家和 18 个不同专业/群体。提高所有群体的代表性仍面临挑战,绝大多数答复(30%)来自外科医生,来自患者/家长群体的比例相对较小(9%)。这还包括管理三种语言的答复、有效传播以及未作为研究问题措辞的答复:这是 CHNRI 首次让患者和家长、临床医生以及研究人员参与到首次问题提交阶段的活动之一,也是首次在全球范围内这样做。我们介绍了我们应对包容性挑战的方法,并报告了相关的人口统计数据,作为一个基准,我们希望未来的 CHNRI 活动能在此基础上有所改进。
{"title":"Addressing barriers to global multidisciplinary stakeholder inclusivity: Lessons from global orofacial cleft research priority setting.","authors":"Niki Kouvroukoglou, Sanita Sandhu, Barbara Delage, Debbie Sell, Nicola Stock, Gareth Davies, Marina Campodonico, Bruce Richard, Zipporah Njeri Gathuya, Mekonen Eshete, Felicity V Mehendale","doi":"10.7189/jogh.14.04261","DOIUrl":"10.7189/jogh.14.04261","url":null,"abstract":"<p><strong>Background: </strong>Inclusivity in research priority setting is fundamental to capturing the opinion of all stakeholders in a research area. Globally, experienced healthcare workers often have deep insights that could impactfully shape future research, and a lack of their involvement in formal research and publications could mean that their voices are insufficiently represented. We aimed to modify the well-established Child Health and Nutrition Research Initiative (CHNRI) methodology to address barriers to inclusivity, which are particularly relevant in healthcare that requires highly multidisciplinary care.</p><p><strong>Methods: </strong>This global research priority-setting exercise for orofacial clefts adapted the CHNRI methodology to include research experts, clinicians from multiple disciplines, and non-technical stakeholders (i.e. patients and parents and non-governmental organisations (NGOs)) on a global basis. A multidisciplinary international steering group proposed and discussed methodological changes to improve inclusivity, including survey edits, subgroups for research questions, a demographics section, translation in French and Spanish, phrasing adaptation, and alternative dissemination techniques.</p><p><strong>Results: </strong>We received 412 responses and 1420 questions, spanning 78 different countries and 18 different specialties/groups. Challenges remain to improve representation of all groups, with the vast majority of answers (30%) being from surgeons and a comparatively small proportion from patient/parent groups (9%). This also includes managing responses in three languages, effective dissemination, and responses that were not worded as research questions.</p><p><strong>Conclusions: </strong>This is one of the first CHNRI exercises to involve patients and parents, clinicians, and researchers in its first question submission stage, and the first ever to do so on a global scale. We describe our approach to addressing inclusivity challenges and report related demographic data to serve as a benchmark upon which we hope future CHNRI exercises will improve.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"14 ","pages":"04261"},"PeriodicalIF":4.5,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11636950/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between ambient particulate matter and latent tuberculosis infection among 198 275 students. 环境颗粒物与 198 275 名学生潜伏肺结核感染之间的关系。
IF 4.5 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-13 DOI: 10.7189/jogh.14.04244
Zhongqi Li, Zhan Wang, Peng Lu, Jingxian Ning, Hui Ding, Limei Zhu, Xiaohua Pei, Qiao Liu

Background: Numerous studies have estimated the impact of outdoor particulate matter (PM) on tuberculosis risk. Nevertheless, whether there is an association between ambient PM and latent tuberculosis infection (LTBI) risk remains uncertain.

Methods: We collected the basic information and LTBI test results of students who underwent freshmen enrolment physical examinations in 68 middle schools from six prefecture-level cities located in eastern China between 2018 and 2021. We also extracted data on air pollutant concentrations and meteorological factors in six cities between 2015 and 2021. We applied the generalised additive model (GAM) to assess the effect of PM on LTBI risk.

Results: We included 198 275 students in the final analysis, of whom 11 721 were diagnosed with LTBI. The LTBI group had higher proportions of males (P < 0.001), individuals of Han nationality (P < 0.001), and body mass index compared to the non-LTBI group (P < 0.001). For each 1-μg/m3 increase in PM10 concentration, the LTBI risk increased by 0.82% (95% confidence interval (CI) = 0.65-1.00), 0.90% (95% CI = 0.73-1.08), and 0.86% (95% CI = 0.69-1.03) when lagged at one, two, and three years, respectively. For PM2.5, the LTBI risk increased by 0.91% (95% CI = 0.63-1.20), 1.05% (95% CI = 0.75-1.36), and 1.32% (95% CI = 0.96-1.69) when lagged at one, two, and three years, respectively.

Conclusions: Outdoor PM concentration was positively correlated with LTBI risk. Considering that many developing countries are facing the dual challenges of high LTBI rates and serious ambient air pollution, reducing outdoor PM concentration would contribute to alleviating their tuberculosis burden.

背景:许多研究估计了室外颗粒物(PM)对结核病风险的影响。然而,环境中的可吸入颗粒物与肺结核潜伏感染(LTBI)风险之间是否存在关联仍不确定:我们收集了 2018 年至 2021 年间华东地区 6 个地级市 68 所中学新生入学体检学生的基本信息和 LTBI 检测结果。我们还提取了 2015 年至 2021 年期间 6 个城市的空气污染物浓度和气象要素数据。我们应用广义相加模型(GAM)评估了可吸入颗粒物对LTBI风险的影响:我们在最终分析中纳入了 198 275 名学生,其中 11 721 人被确诊为 LTBI。PM10浓度增加3倍时,LTBI风险分别增加0.82%(95%置信区间(CI)=0.65-1.00)、0.90%(95%置信区间(CI)=0.73-1.08)和0.86%(95%置信区间(CI)=0.69-1.03)。PM2.5滞后一年、两年和三年时,LTBI风险分别增加0.91%(95% CI = 0.63-1.20)、1.05%(95% CI = 0.75-1.36)和1.32%(95% CI = 0.96-1.69):室外可吸入颗粒物浓度与LTBI风险呈正相关。考虑到许多发展中国家正面临着LTBI发病率高和环境空气污染严重的双重挑战,降低室外可吸入颗粒物浓度将有助于减轻这些国家的结核病负担。
{"title":"Association between ambient particulate matter and latent tuberculosis infection among 198 275 students.","authors":"Zhongqi Li, Zhan Wang, Peng Lu, Jingxian Ning, Hui Ding, Limei Zhu, Xiaohua Pei, Qiao Liu","doi":"10.7189/jogh.14.04244","DOIUrl":"10.7189/jogh.14.04244","url":null,"abstract":"<p><strong>Background: </strong>Numerous studies have estimated the impact of outdoor particulate matter (PM) on tuberculosis risk. Nevertheless, whether there is an association between ambient PM and latent tuberculosis infection (LTBI) risk remains uncertain.</p><p><strong>Methods: </strong>We collected the basic information and LTBI test results of students who underwent freshmen enrolment physical examinations in 68 middle schools from six prefecture-level cities located in eastern China between 2018 and 2021. We also extracted data on air pollutant concentrations and meteorological factors in six cities between 2015 and 2021. We applied the generalised additive model (GAM) to assess the effect of PM on LTBI risk.</p><p><strong>Results: </strong>We included 198 275 students in the final analysis, of whom 11 721 were diagnosed with LTBI. The LTBI group had higher proportions of males (P < 0.001), individuals of Han nationality (P < 0.001), and body mass index compared to the non-LTBI group (P < 0.001). For each 1-μg/m<sup>3</sup> increase in PM<sub>10</sub> concentration, the LTBI risk increased by 0.82% (95% confidence interval (CI) = 0.65-1.00), 0.90% (95% CI = 0.73-1.08), and 0.86% (95% CI = 0.69-1.03) when lagged at one, two, and three years, respectively. For PM<sub>2.5</sub>, the LTBI risk increased by 0.91% (95% CI = 0.63-1.20), 1.05% (95% CI = 0.75-1.36), and 1.32% (95% CI = 0.96-1.69) when lagged at one, two, and three years, respectively.</p><p><strong>Conclusions: </strong>Outdoor PM concentration was positively correlated with LTBI risk. Considering that many developing countries are facing the dual challenges of high LTBI rates and serious ambient air pollution, reducing outdoor PM concentration would contribute to alleviating their tuberculosis burden.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"14 ","pages":"04244"},"PeriodicalIF":4.5,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11636952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Global Health
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1