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DIAGNOSTIC PERFORMANCE OF MACHINE LEARNING-AIDED PROXIMAL CARIES DETECTION: A SYSTEMATIC REVIEW AND META-ANALYSIS 机器学习辅助近端龋齿检测的诊断性能:系统回顾和荟萃分析
IF 4 4区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-03-01 Epub Date: 2026-01-02 DOI: 10.1016/j.jebdp.2025.102225
KAIXIN GUO MDS , MADELINE JUN YU YON PhD , YANQI YANG PhD , COLMAN PATRICK MCGRATH PhD , PHOEBE PUI YING LAM PhD

Objectives

The systematic review aimed to evaluate the diagnostic performance of machine learning in detecting proximal caries through radiographic modalities compared to expert consensus.

Materials and methods

A strategic literature search was carried out across 4 electronic databases, with 2 independent reviewers for screening and data extraction. Measures as sensitivity, specificity, positive (LR+) and negative likelihood ratios (LR-), area under the receiver operating characteristic curve (AUC-ROC) and diagnostic odds ratio (DOR) were calculated. Risk of bias was assessed using the Quality Assessment tool for Diagnostic Accuracy Studies (QUADAS-2). Subgroup analysis was performed based on the data modalities and image augmentation. The certainty of evidence was evaluated according to the Grading of Recommendation, Assessment, Development, and Evaluation (GRADE) framework.

Results

Following a thorough review of 2439 studies, 28 studies met the inclusion criteria. Eleven studies were included in the meta-analysis. The pooled sensitivity and specificity were 0.84 (95% Confidence Interval [95% CI] 0.78-0.88) and 0.93 (95% CI 0.90-0.97) respectively. The LR+ and LR- were 14.00 (95% CI 8.30-23.40) and 0.17 (95% CI 0.12-0.23) respectively. The pooled AUC-ROC was 0.95 (95% CI 0.17-1.00), and DOR was 84.08 (95% CI 40.54-174.40). The limited certainty of evidence indicated that all radiographic modalities have comparable specificity in detecting proximal caries, while cone beam computer tomography demonstrates significantly higher sensitivity. No difference between the presence or absence of image augmentation prior to machine learning model training was found. Most studies (22/28) showed high risk of bias. Certainty of evidence was low.

Conclusions

Machine learning models demonstrated acceptable diagnostic performance for proximal caries detection, with cone beam computed tomography (CBCT) potentially offering higher sensitivity. However, future studies to investigate the AI performance across various depths and types of dentitions are warranted due to limited evidence certainty.
目的本系统综述旨在评估机器学习在通过x线摄影方式检测近端龋齿方面的诊断性能,并与专家共识进行比较。材料和方法对4个电子数据库进行战略性文献检索,由2名独立审稿人进行筛选和数据提取。计算敏感性、特异性、阳性(LR+)和阴性似然比(LR-)、受试者工作特征曲线下面积(AUC-ROC)和诊断优势比(DOR)等指标。使用诊断准确性研究质量评估工具(QUADAS-2)评估偏倚风险。根据数据模式和图像增强进行亚组分析。根据推荐、评估、发展和评价分级(GRADE)框架评估证据的确定性。经过对2439项研究的全面回顾,有28项研究符合纳入标准。荟萃分析纳入了11项研究。合并敏感性和特异性分别为0.84(95%可信区间[95% CI] 0.78 ~ 0.88)和0.93 (95% CI 0.90 ~ 0.97)。LR+和LR-分别为14.00 (95% CI 8.30-23.40)和0.17 (95% CI 0.12-0.23)。合并AUC-ROC为0.95 (95% CI 0.17-1.00), DOR为84.08 (95% CI 40.54-174.40)。证据的有限确定性表明,所有放射成像方式在检测近端龋齿方面具有相当的特异性,而锥束计算机断层扫描显示出明显更高的灵敏度。在机器学习模型训练之前,没有发现图像增强的存在或不存在差异。大多数研究(22/28)显示高偏倚风险。证据的确定性很低。结论机器学习模型在近端龋齿检测中表现出可接受的诊断性能,锥束计算机断层扫描(CBCT)可能具有更高的灵敏度。然而,由于证据确定性有限,未来研究人工智能在不同深度和牙列类型上的表现是有必要的。
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引用次数: 0
EVIDENCE-BASED PEDIATRIC DENTISTRY: THE FIRST TWENTY-FIVE YEARS OF TRANSFORMATION AND THE NEXT 循证儿科牙科:前25年的转变和下一个
IF 4 4区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-03-01 Epub Date: 2025-11-16 DOI: 10.1016/j.jebdp.2025.102222
NICOLA INNES
Over the past quarter-century, pediatric dentistry has shifted from an expert-opinion-driven craft-often extrapolated from adult dental care, to become a discipline anchored in rigorous, child-specific evidence. This transformation reflects the maturation of evidence-based dentistry (EBD): integrating the best available research with clinical expertise and the values and preferences of children and their families. As we celebrate the Journal of Evidence-Based Dental Practice at 25 years of age, this article charts some milestones in pediatric EBD that show how clinical practice has led to scientific enquiry, research investigations and widespread changes in practice. The examples used are the Hall Technique, Atraumatic Restorative Treatment and pulp canal obliteration in dental trauma management. A pathway to improve research impact is proposed, stretching from ensuring research relevance and methodological rigor through to talking and listening to those who are stakeholders, planning implementation of findings, using core- and patient relevant- outcome sets, public communication and open science. Change does not have to be global to be important: locally tailored, context-aware research and its implementation can improve children’s oral healthcare, reduce inequalities and deliver value. This article is part of the special issue "Celebrating 25 Years of the Journal of Evidence-Based Dental Practice."
在过去的四分之一世纪里,儿童牙科已经从一种专家意见驱动的工艺(通常从成人牙科护理中推断出来)转变为一种以严格的、针对儿童的证据为基础的学科。这种转变反映了循证牙科(EBD)的成熟:将现有的最佳研究与临床专业知识以及儿童及其家庭的价值观和偏好相结合。在我们庆祝《循证牙科实践杂志》25周年之际,这篇文章描绘了儿科EBD的一些里程碑,展示了临床实践如何导致科学探究、研究调查和实践中的广泛变化。使用的例子是霍尔技术,无创伤修复治疗和牙髓管闭塞治疗。提出了一条改善研究影响的途径,从确保研究的相关性和方法的严谨性,一直延伸到与利益相关者交谈和倾听,规划结果的实施,使用核心和患者相关的结果集,公共沟通和开放科学。重要的改变不一定是全球性的:因地制宜、了解情况的研究及其实施可以改善儿童口腔保健、减少不平等现象并创造价值。本文是《庆祝循证牙科实践杂志25周年》特刊的一部分。
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引用次数: 0
COMPUTER-ASSISTED IMPLANT SURGERY MAY ENHANCE PLACEMENT ACCURACY, WITH ROBOTIC APPROACHES OUTPERFORMING CONVENTIONAL TECHNIQUES 计算机辅助植入手术可以提高植入精度,机器人方法优于传统技术
IF 4 4区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-03-01 Epub Date: 2025-10-13 DOI: 10.1016/j.jebdp.2025.102205
IMAN ABD-ELWAHAB RADI (Reviewers), FATMA ELZAHRAA MOHAMED

Article Title and Bibliographic Information

Khaohoen A, Powcharoen W, Yoda N, Rungsiyakull C, Rungsiyakull P. Accuracy in dental implant placement: A systematic review and meta-analysis comparing computer-assisted (static, dynamic, robotics) and non-computer-assisted (freehand, conventional guide) approaches. J Prosthet Dent. 2025;134:91.e1-91.e25. doi:1 0.1016/j.prosdent.2025.03.038

Source of Funding

Th review was funded by Chiang Mai University, Chiang Mai, Thailand.

Type of Study/Design

Systematic Review with Meta-analysis of Data (SRMA).
kaohoen A, Powcharoen W, Yoda N, Rungsiyakull C, Rungsiyakull P.人工牙种植体植入的准确性:计算机辅助(静态、动态、机器人)和非计算机辅助(徒手、传统指导)方法的系统评价和meta分析。[J] .中华口腔医学杂志,2015;34(4):991 - 991。本文由泰国清迈大学(Chiang Mai University, Chiang Mai, Thailand)资助。研究类型/设计采用数据荟萃分析(SRMA)的系统评价。
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引用次数: 0
BARRIERS, LESSONS AND POSSIBLE IMPROVEMENTS WHEN IMPLEMENTING EVIDENCE-BASED TEACHING: A NARRATIVE REVIEW 实施循证教学时的障碍、教训和可能的改进:叙述性回顾
IF 4 4区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-03-01 Epub Date: 2026-01-06 DOI: 10.1016/j.jebdp.2026.102229
PATRÍCIA PAULETTO , MURILO FERNANDO NEUPPMANN FERES , CRISTINE MIRON STEFANI , GRAZIELA DE LUCA CANTO , CARLOS FLORES-MIR
Evidence-based dentistry (EBD) has been widely promoted as a cornerstone of contemporary dental education and clinical decision-making. Its integration into undergraduate and graduate curricula aims to equip future professionals with the skills needed to critically appraise scientific evidence, apply research findings to clinical scenarios, and deliver patient-centered care. Despite its broad endorsement, the effectiveness of EBD education in producing sustained changes in clinical behavior and patient outcomes remains insufficiently established. This narrative review discusses key teaching strategies, curricular integration models, and real-world implementation experiences related to EBD education, while critically examining persistent challenges and gaps in the current evidence base. Active learning approaches, including small-group learning, journal clubs, hybrid formats, and structured mentorship programs, appear to enhance students’ knowledge, attitudes, and critical appraisal skills. However, structural constraints, limited faculty training, curricular overload, and difficulties in translating academic competencies into clinical practice continue to hinder effective implementation. Additionally, emerging digital and artificial intelligence–based tools offer promising opportunities to support evidence synthesis, guideline updating, and personalized learning, although concerns regarding accuracy, bias, and scientific integrity remain. Overall, while EBD education posits clear benefits in improving knowledge and attitudes, robust longitudinal evidence demonstrating its long-term impact on clinical practice is still lacking. Addressing these challenges will require institutional commitment, continuous faculty development, standardized assessment strategies, and the thoughtful integration of technological innovations to ensure the sustainable adoption of EBD in dental education.
循证牙科(EBD)已被广泛推广为当代牙科教育和临床决策的基石。它与本科和研究生课程相结合,旨在为未来的专业人员提供批判性评估科学证据、将研究成果应用于临床场景和提供以患者为中心的护理所需的技能。尽管得到了广泛的认可,EBD教育在产生临床行为和患者预后的持续变化方面的有效性仍然没有得到充分的证实。这篇叙述性综述讨论了与EBD教育相关的关键教学策略、课程整合模式和现实世界的实施经验,同时批判性地审视了当前证据基础上持续存在的挑战和差距。积极的学习方法,包括小组学习、期刊俱乐部、混合形式和结构化指导计划,似乎可以提高学生的知识、态度和批判性评估技能。然而,结构限制、有限的教师培训、课程超载以及将学术能力转化为临床实践的困难继续阻碍有效实施。此外,新兴的基于数字和人工智能的工具为支持证据合成、指南更新和个性化学习提供了有希望的机会,尽管对准确性、偏见和科学完整性的担忧仍然存在。总的来说,虽然EBD教育在提高知识和态度方面有明显的好处,但仍然缺乏强有力的纵向证据来证明其对临床实践的长期影响。应对这些挑战需要机构的承诺,持续的师资发展,标准化的评估策略,以及技术创新的深思熟虑的整合,以确保EBD在牙科教育中的可持续采用。
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引用次数: 0
THE UTILITY OF DEEP LEARNING MODEL IN CLINICAL TREATMENT DECISION-MAKING OF MANDIBULAR THIRD MOLAR: A SYSTEMATIC REVIEW AND META-ANALYSIS 深度学习模型在下颌第三磨牙临床治疗决策中的应用:系统回顾和荟萃分析
IF 4 4区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 Epub Date: 2025-05-02 DOI: 10.1016/j.jebdp.2025.102164
CHENJIE ZHAO , XUESHAN BAI , ZIYANG LIU , WENJIE CHENG , SONGXIA XIA , LI TENG , LIYA YANG

Objectives

To evaluate the effectiveness of deep learning (DL) in medical imaging for improving clinical procedures related to the mandibular third molar (MM3).

Methods

Our systematic search included databases such as PubMed, EMBASE, Web of Science, and the Cochrane Library, up to April 10, 2024. The Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) tool was used to assess the potential bias and clinical relevance of the studies. To examine the interaction between MM3 and the inferior alveolar nerve (IAN), we conducted a meta-analysis using a bivariate mixed-effects model to compare the performance of DL methods with that of human experts.

Results

In this comprehensive review, a total of 33 scholarly works involving 45,029 imaging instances were analyzed. Among these, 15 studies specifically focused on evaluating the performance of DL methods in identifying the spatial relationship between MM3 and IAN. The aggregated results showed that DL achieved a diagnostic sensitivity of 0.89 (95% CI, 0.85-0.93) and a specificity of 0.88 (95% CI, 0.80-0.93). In parallel, a comparative meta-analysis that included assessments from 16 clinical experts revealed slightly lower sensitivity (0.76; 95% CI, 0.65-0.85) and specificity (0.86; 95% CI, 0.70-0.94). Additionally, the review explored the utility of DL in predictive modeling of MM3 eruption, assessing the complexity of extraction procedures, and identifying MM3 characteristics. The 18 studies in this area demonstrated diagnostic sensitivity ranging from 0.80 to 0.94 and specificity from 0.75 to 0.97, collectively highlighting the strong prognostic capabilities of DL in these clinical applications.

Conclusions

DL has demonstrated remarkable efficacy, especially in precisely identifying the anatomical connections between MM3 and IAN. Moreover, DL excels in identifying, categorizing, and assessing the complexity associated with MM3 extractions. This study confirms the substantial value of DL, particularly when utilized through image-based methods, in improving clinical management strategies for MM3. The creation of intelligent diagnostic tools using oral panoramic radiographs (OPGs) is strongly encouraged to assist physicians, especially those with limited clinical experience, in enhancing their diagnostic accuracy. These advancements in DL applications are expected to significantly improve the accuracy and efficiency of clinical diagnoses in oral and maxillofacial surgeries.
目的评价深度学习(DL)在医学影像学中改进下颌第三磨牙(MM3)临床操作的有效性。方法系统检索截至2024年4月10日的PubMed、EMBASE、Web of Science、Cochrane Library等数据库。使用诊断准确性研究质量评估-2 (QUADAS-2)工具评估研究的潜在偏倚和临床相关性。为了研究MM3与下肺泡神经(IAN)之间的相互作用,我们使用双变量混合效应模型进行了荟萃分析,以比较DL方法与人类专家的性能。结果本综述共分析了33篇学术论文,涉及45,029例影像学病例。其中,有15项研究专门评估了DL方法在识别MM3和IAN之间空间关系方面的性能。综合结果显示,DL的诊断敏感性为0.89 (95% CI, 0.85-0.93),特异性为0.88 (95% CI, 0.80-0.93)。与此同时,一项包括16位临床专家评估的比较荟萃分析显示,敏感性(0.76;95% CI, 0.65-0.85)和特异性(0.86,95% CI, 0.70-0.94)略低。此外,本文还探讨了DL在MM3喷发预测建模中的应用,评估提取程序的复杂性,并确定MM3特征。该领域的18项研究表明,DL的诊断敏感性为0.80 ~ 0.94,特异性为0.75 ~ 0.97,共同强调了DL在这些临床应用中的强大预后能力。结论sdl具有显著的疗效,特别是在精确识别MM3与IAN之间的解剖联系方面。此外,DL在识别、分类和评估与MM3提取相关的复杂性方面表现出色。本研究证实了DL在改善MM3临床管理策略方面的巨大价值,特别是通过基于图像的方法加以利用时。强烈鼓励使用口腔全景x线片(OPGs)创建智能诊断工具,以帮助医生,特别是那些临床经验有限的医生,提高他们的诊断准确性。DL应用的这些进步有望显著提高口腔颌面外科临床诊断的准确性和效率。
{"title":"THE UTILITY OF DEEP LEARNING MODEL IN CLINICAL TREATMENT DECISION-MAKING OF MANDIBULAR THIRD MOLAR: A SYSTEMATIC REVIEW AND META-ANALYSIS","authors":"CHENJIE ZHAO ,&nbsp;XUESHAN BAI ,&nbsp;ZIYANG LIU ,&nbsp;WENJIE CHENG ,&nbsp;SONGXIA XIA ,&nbsp;LI TENG ,&nbsp;LIYA YANG","doi":"10.1016/j.jebdp.2025.102164","DOIUrl":"10.1016/j.jebdp.2025.102164","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the effectiveness of deep learning (DL) in medical imaging for improving clinical procedures related to the mandibular third molar (MM3).</div></div><div><h3>Methods</h3><div>Our systematic search included databases such as PubMed, EMBASE, Web of Science, and the Cochrane Library, up to April 10, 2024. The Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) tool was used to assess the potential bias and clinical relevance of the studies. To examine the interaction between MM3 and the inferior alveolar nerve (IAN), we conducted a meta-analysis using a bivariate mixed-effects model to compare the performance of DL methods with that of human experts.</div></div><div><h3>Results</h3><div>In this comprehensive review, a total of 33 scholarly works involving 45,029 imaging instances were analyzed. Among these, 15 studies specifically focused on evaluating the performance of DL methods in identifying the spatial relationship between MM3 and IAN. The aggregated results showed that DL achieved a diagnostic sensitivity of 0.89 (95% CI, 0.85-0.93) and a specificity of 0.88 (95% CI, 0.80-0.93). In parallel, a comparative meta-analysis that included assessments from 16 clinical experts revealed slightly lower sensitivity (0.76; 95% CI, 0.65-0.85) and specificity (0.86; 95% CI, 0.70-0.94). Additionally, the review explored the utility of DL in predictive modeling of MM3 eruption, assessing the complexity of extraction procedures, and identifying MM3 characteristics. The 18 studies in this area demonstrated diagnostic sensitivity ranging from 0.80 to 0.94 and specificity from 0.75 to 0.97, collectively highlighting the strong prognostic capabilities of DL in these clinical applications.</div></div><div><h3>Conclusions</h3><div>DL has demonstrated remarkable efficacy, especially in precisely identifying the anatomical connections between MM3 and IAN. Moreover, DL excels in identifying, categorizing, and assessing the complexity associated with MM3 extractions. This study confirms the substantial value of DL, particularly when utilized through image-based methods, in improving clinical management strategies for MM3. The creation of intelligent diagnostic tools using oral panoramic radiographs (OPGs) is strongly encouraged to assist physicians, especially those with limited clinical experience, in enhancing their diagnostic accuracy. These advancements in DL applications are expected to significantly improve the accuracy and efficiency of clinical diagnoses in oral and maxillofacial surgeries.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 4","pages":"Article 102164"},"PeriodicalIF":4.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144880265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MAXILLARY EXPANSION MAY NOT LEAD TO SIGNIFICANT SAGITTAL EFFECTS IN GROWING CLASS II PATIENTS 在生长中的ii类患者中,上颌扩张可能不会导致显著的矢状面效应
IF 4 4区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 Epub Date: 2025-06-18 DOI: 10.1016/j.jebdp.2025.102173
XIAOJIN WU (Reviewers), WEI LU, FANG HUA

Article Title and Bibliographic Information

Impact of maxillary expansion on the sagittal skeletal and dental parameters of growing Class II patients: A systematic review with meta-analysis. Cannatà D, Galdi M, Scelza C, Simeon V, Giordano F, Martina S. Orthod Craniofac Res. 2025 Feb;28(1):116-132.

Source of Funding

None.

Type of Study/Design

Systematic review with meta-analysis
上颌扩张对生长II类患者矢状面骨骼和牙齿参数的影响:一项系统综述和荟萃分析。张建军,张建军,李建军,等。颅脑外科杂志[j] .中华外科杂志,2015,28(1):116-132。资金来源无。研究类型/设计:采用荟萃分析的系统评价
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引用次数: 0
Ethical Aspects of Implementing Dental Patient-Reported Outcomes On Different Patient Populations: A Narrative Review 在不同患者群体中实施牙科患者报告结果的伦理方面:叙述回顾
IF 4 4区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 Epub Date: 2025-08-23 DOI: 10.1016/j.jebdp.2025.102193
ASIYA M. ATTAR BDS, MBA, KASTURI SHUKLA MBA, PhD

Introduction

Dental Patient-Reported Outcomes (dPROs) are patient-provided information regarding treatment outcomes and oral health-related quality of life. However, considering the sensitive health information collected during the implementation of dPROs, it is important to study the relevant ethical aspects. Hence, this review synthesized the current evidence to explain and critically evaluate the key ethical issues associated with dPROs use in various patient populations.

Methods

A narrative review approach was employed to analyse ethical challenges reported in the literature concerning the use and implementation of dPROs across various population groups. Relevant literature from 2005 to 2024 was sourced using databases like Google Scholar, Scopus, and Web of Science.

Results

Four key ethical issues were identified: 1) acquiring Informed Consent, 2) maintaining Privacy and Confidentiality, 3) addressing the disparities in Equity of Access to oral care, and 4) upholding Cultural Sensitivity in diverse communities.

Discussion

This study offered insights into the application of the identified four key ethical issues within diverse populations. Additionally, the study provides constructive recommendations for the ethical implementation of dPROs in various patient populations. Ethical challenges related to less-researched populations, various other ethical aspects, and emerging ethical issues were also explored.

Conclusion

Future research should focus on refining informed consent processes for vulnerable populations and strengthening data privacy. Additionally, the development of culturally adapted dPRO tools could enhance communication and improve patient satisfaction and patient experience. Addressing these concerns is crucial for ensuring the ethical deployment of dPROs while safeguarding patient rights and welfare.
牙科患者报告的结果(dPROs)是患者提供的关于治疗结果和口腔健康相关生活质量的信息。然而,考虑到在实施dPROs期间收集的敏感健康信息,研究相关的伦理方面是很重要的。因此,本综述综合了目前的证据,以解释和批判性地评估与在不同患者群体中使用dPROs相关的关键伦理问题。方法采用叙述性回顾法分析文献中关于在不同人群中使用和实施dPROs的伦理挑战。2005年至2024年的相关文献来源于谷歌Scholar、Scopus和Web of Science等数据库。结果确定了四个关键的伦理问题:1)获得知情同意;2)维护隐私和保密;3)解决口腔护理公平获取的差异;4)维护不同社区的文化敏感性。本研究为确定的四个关键伦理问题在不同人群中的应用提供了见解。此外,该研究为dPROs在不同患者群体中的伦理实施提供了建设性的建议。与研究较少的人群相关的伦理挑战,各种其他伦理方面,以及新兴的伦理问题也进行了探讨。结论未来的研究应侧重于完善弱势群体的知情同意流程和加强数据隐私。此外,开发适应文化的dPRO工具可以加强沟通,提高患者满意度和患者体验。解决这些问题对于确保在维护患者权利和福利的同时合乎道德地部署dPROs至关重要。
{"title":"Ethical Aspects of Implementing Dental Patient-Reported Outcomes On Different Patient Populations: A Narrative Review","authors":"ASIYA M. ATTAR BDS, MBA,&nbsp;KASTURI SHUKLA MBA, PhD","doi":"10.1016/j.jebdp.2025.102193","DOIUrl":"10.1016/j.jebdp.2025.102193","url":null,"abstract":"<div><h3>Introduction</h3><div>Dental Patient-Reported Outcomes (dPROs) are patient-provided information regarding treatment outcomes and oral health-related quality of life. However, considering the sensitive health information collected during the implementation of dPROs, it is important to study the relevant ethical aspects. Hence, this review synthesized the current evidence to explain and critically evaluate the key ethical issues associated with dPROs use in various patient populations.</div></div><div><h3>Methods</h3><div>A narrative review approach was employed to analyse ethical challenges reported in the literature concerning the use and implementation of dPROs across various population groups. Relevant literature from 2005 to 2024 was sourced using databases like Google Scholar, Scopus, and Web of Science.</div></div><div><h3>Results</h3><div>Four key ethical issues were identified: 1) acquiring Informed Consent, 2) maintaining Privacy and Confidentiality, 3) addressing the disparities in Equity of Access to oral care, and 4) upholding Cultural Sensitivity in diverse communities.</div></div><div><h3>Discussion</h3><div>This study offered insights into the application of the identified four key ethical issues within diverse populations. Additionally, the study provides constructive recommendations for the ethical implementation of dPROs in various patient populations. Ethical challenges related to less-researched populations, various other ethical aspects, and emerging ethical issues were also explored.</div></div><div><h3>Conclusion</h3><div>Future research should focus on refining informed consent processes for vulnerable populations and strengthening data privacy. Additionally, the development of culturally adapted dPRO tools could enhance communication and improve patient satisfaction and patient experience. Addressing these concerns is crucial for ensuring the ethical deployment of dPROs while safeguarding patient rights and welfare.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 4","pages":"Article 102193"},"PeriodicalIF":4.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145104165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CLINICAL EFFECT OF LOCAL ALOE VERA USE AS AN ADJUNCT TO PERIODONTAL THERAPY: A SYSTEMATIC REVIEW AND META-ANALYSIS 局部芦荟作为辅助牙周治疗的临床效果:系统回顾和荟萃分析
IF 4.1 4区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 Epub Date: 2025-05-20 DOI: 10.1016/j.jebdp.2025.102167
CHENGZHI XIE , ZHIHUI JING , MINGYU XUE

Objectives

Aloe Vera might be beneficial to improve periodontal condition. This systematic review and meta-analysis aimed to investigate Aloe Vera’s clinical efficacy as an adjunct to scaling and root planning (SRP) for nonsurgical periodontal therapy.

Methods

We included relevant randomized controlled trials (RCTs) comparing the effectiveness of Aloe Vera (I) with a (placebo) control (C) on periodontal parameters (O) in in adults with periodontitis (P) (registration number: CRD42022336946). PubMed, Cochrane Library, Embase, and Web of Science were searched. Mean difference (MD) with standard deviations of clinical outcomes were extracted and pooled from three studies.

Results

Three studies were included in the systematic review and meta-analysis. Adjunctive Aloe Vera treatment reduced probing pocket depth (PPD), with MD = −0.47 (−0.78/−0.16) at 3 months, MD = −0.29 (−0.53/−0.06) at 6 months, and MD: −1.06 (−2.04/−0.08) at 12 months, compared to the control group. Overall differences for clinical attachment level (CAL) were found to be −0.56 (−0.85/−0.27) at 6 months and −0.98 (−1.28/−0.68) at 12 months, which indicated a statistically significant result favoring the test group over the control group. No significant differences were observed in reducing plaque index (PI), bleeding index (BI) at 6 months and CAL at 3 months in the local administration of Aloe Vera to SRP. Adjunctive Aloe Vera treatment reduced BI (MD: −0.40; −0.62/−0.18) at 12 months with respect to the control group.

Conclusions

In comparison to SRP alone/placebo, the supplementary use of Aloe Vera in SRP results in improved periodontal treatment outcomes.

Limitations

Limited by the quality and number of studies, the evidence was not reliable enough to support any clinical advice.

Clinical significance

The subgingival administration of Aloe Vera may be clinically efficacious for managing periodontal diseases.
目的芦荟具有改善牙周状况的作用。本系统综述和荟萃分析旨在探讨芦荟作为非手术牙周治疗的刮治和牙根规划(SRP)辅助手段的临床疗效。方法纳入相关的随机对照试验(RCTs),比较芦荟(I)与安慰剂(C)对照(C)对牙周炎(P)成人牙周参数(O)的有效性(注册号:CRD42022336946)。检索了PubMed、Cochrane Library、Embase和Web of Science。从三个研究中提取并汇总临床结果的平均差异(MD)和标准差。结果系统评价和荟萃分析纳入了3项研究。辅助芦荟治疗降低了探测袋深度(PPD),与对照组相比,3个月时MD = −0.47(−0.78/−0.16),6个月时MD = −0.29(−0.53/−0.06),12个月时MD:−1.06(−2.04/−0.08)。临床依恋水平(CAL)的总体差异在6个月时为- 0.56(- 0.85/ - 0.27),在12个月时为- 0.98(- 1.28/ - 0.68),这表明试验组优于对照组有统计学意义。在降低斑块指数(PI)、6个月出血指数(BI)和3个月CAL方面,局部给药芦荟与SRP无显著差异。芦荟辅助治疗可降低BI (MD:−0.40;- 0.62/ - 0.18), 12个月时与对照组相比。结论与单纯SRP /安慰剂相比,在SRP中补充使用芦荟可改善牙周治疗效果。局限性受研究质量和数量的限制,证据不够可靠,无法支持任何临床建议。临床意义芦荟龈下给药治疗牙周病在临床上可能是有效的。
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引用次数: 0
WHICH ORAL HYGIENE PROTOCOL SHOULD BE FOLLOWED BY PATIENTS WITH FIXED ORTHODONTIC APPLIANCES? A RANDOMIZED CLINICAL TRIAL 使用固定正畸矫治器的患者应遵循哪些口腔卫生方案?一项随机临床试验
IF 4 4区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 Epub Date: 2025-08-12 DOI: 10.1016/j.jebdp.2025.102192
MOHAMMED A. ELBANNA , SHAHIRA A. ELBANNA , FATMA ABDELSAYED , MOHAMED ABD-EL-GHAFOUR

Objective

The aim of this study was to compare the effect of three different oral hygiene protocols on the amount of Streptococcus mutans (S. mutans) colonization in adult patients with fixed orthodontic appliance.

Methods

A total of 27 patients who fulfilled the eligibility criteria were randomly allocated in the study. After bonding of the fixed appliance, patients were randomly allocated into 3 groups, Group I (conventional manual toothbrushing with fluoridated toothpaste), Group II (Conventional manual toothbrushing combined with interdental brushes) and Group III (Conventional manual toothbrushing combined with interdental brushes and chlorhexidine (CHX) mouthwash). Saliva samples were collected from each patient at two timelines; Before bonding (T0) and 1 month after bonding (T1), then sent for microbial analysis to calculate S. mutans viable count (CFU/mL).

Results

T1 vs T0: Group I showed significant increase in S. mutans viable counts (P = .0117), Group II showed no significant changes in S. mutans levels (P = .425), while Group III showed significant decrease in S. mutans viable counts (P = 0.0078). Upon comparing the three oral hygiene protocols, both group II and group III exhibited prominent impact on oral hygiene whether by maintaining or reducing S. mutans levels, respectively.

Conclusion

Conventional manual toothbrush combined with interdental brush protocol with or without CHX were efficient protocols for improving oral hygiene in orthodontic patients. Using conventional manual toothbrushes alone was the least effective oral hygiene protocol. Registration NCT05016713. The protocol was published before trial commencement.
目的比较三种不同口腔卫生方案对成年固定正畸矫治器患者变形链球菌定植量的影响。方法随机选取符合入选标准的患者27例。固定矫治器粘接后,将患者随机分为3组,ⅰ组(常规手动刷牙加氟牙膏)、ⅱ组(常规手动刷牙加牙间刷)、ⅲ组(常规手动刷牙加牙间刷加氯己定(CHX)漱口水)。在两个时间线收集每位患者的唾液样本;结合前(T0)和结合后1个月(T1)进行微生物分析,计算变形链球菌活菌数(CFU/mL)。结果st1组与T0组比较:1组突变链球菌活菌数显著增加(P = )。0117), II组的S. mutans水平无显著变化(P = )。425),而III组的S. mutans活菌计数显著降低(P = 0.0078)。通过比较三种口腔卫生方案,II组和III组分别通过维持或减少变形链球菌水平对口腔卫生表现出显著的影响。结论常规手动牙刷联合牙间刷方案是改善正畸患者口腔卫生的有效方案。仅使用传统的手动牙刷是最不有效的口腔卫生方案。登记NCT05016713。该议定书在审判开始前公布。
{"title":"WHICH ORAL HYGIENE PROTOCOL SHOULD BE FOLLOWED BY PATIENTS WITH FIXED ORTHODONTIC APPLIANCES? A RANDOMIZED CLINICAL TRIAL","authors":"MOHAMMED A. ELBANNA ,&nbsp;SHAHIRA A. ELBANNA ,&nbsp;FATMA ABDELSAYED ,&nbsp;MOHAMED ABD-EL-GHAFOUR","doi":"10.1016/j.jebdp.2025.102192","DOIUrl":"10.1016/j.jebdp.2025.102192","url":null,"abstract":"<div><h3>Objective</h3><div>The aim of this study was to compare the effect of three different oral hygiene protocols on the amount of <em>Streptococcus mutans (S. mutans)</em> colonization in adult patients with fixed orthodontic appliance.</div></div><div><h3>Methods</h3><div>A total of 27 patients who fulfilled the eligibility criteria were randomly allocated in the study. After bonding of the fixed appliance, patients were randomly allocated into 3 groups, Group I (conventional manual toothbrushing with fluoridated toothpaste), Group II (Conventional manual toothbrushing combined with interdental brushes) and Group III (Conventional manual toothbrushing combined with interdental brushes and chlorhexidine (CHX) mouthwash). Saliva samples were collected from each patient at two timelines; Before bonding (T0) and 1 month after bonding (T1), then sent for microbial analysis to calculate <em>S. mutans</em> viable count (CFU/mL).</div></div><div><h3>Results</h3><div>T1 vs T0: Group I showed significant increase in <em>S. mutans</em> viable counts (<em>P</em> = .0117), Group II showed no significant changes in <em>S. mutans</em> levels (<em>P</em> = .425), while Group III showed significant decrease in <em>S. mutans</em> viable counts (<em>P</em> = 0.0078). Upon comparing the three oral hygiene protocols, both group II and group III exhibited prominent impact on oral hygiene whether by maintaining or reducing <em>S. mutans</em> levels, respectively.</div></div><div><h3>Conclusion</h3><div>Conventional manual toothbrush combined with interdental brush protocol with or without CHX were efficient protocols for improving oral hygiene in orthodontic patients. Using conventional manual toothbrushes alone was the least effective oral hygiene protocol. Registration NCT05016713. The protocol was published before trial commencement.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 4","pages":"Article 102192"},"PeriodicalIF":4.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144996568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FLUORIDE APPEARS EFFECTIVE AGAINST RADIATION CARIES, BUT MORE RIGOROUS TRIALS ARE NEEDED 氟化物似乎对放射性龋齿有效,但还需要更严格的试验
IF 4.1 4区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 Epub Date: 2025-07-03 DOI: 10.1016/j.jebdp.2025.102174
Linda L. Cheng (Reviewer)

Article Title and Bibliographic Information

Luka B, Fiedler A, Ganss C, Soetedjo V, Vach K, Schlueter N. PREVENTING CARIES AFTER RADIOTHERAPY TO THE HEAD AND NECK REGION - A SYSTEMATIC REVIEW. J Evid Based Dent Pract. 2024;24(3):101989. doi:10.1016/j.jebdp.2024.101989.

Source of Funding

The Department of Operative Dentistry and Periodontology, Center for Dental Medicine, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Type of Study/Design

Systematic review

Conflict of interest

The authors declare no conflicts of interest.
luka B, Fiedler A, Ganss C, Soetedjo V, Vach K, Schlueter N.头颈部放疗后预防龋齿的系统综述。[J] .中文信息学报,2014;24(3):101989。doi: 10.1016 / j.jebdp.2024.101989。经费来源:德国弗莱堡大学医学院,弗莱堡医学中心,牙科医学中心,牙外科和牙周病学系。研究类型/设计系统综述利益冲突作者声明无利益冲突。
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引用次数: 0
期刊
Journal of Evidence-Based Dental Practice
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