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Journal of Evidence-Based Dental Practice最新文献

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IN SIMPLER MALOCCLUSION TYPES, CLEAR ALIGNERS COULD BE CONSIDERED AFTER CAREFUL CONSIDERATION OF OCCLUSAL AND ADHERENCE FACTORS 在简单的错牙合类型中,在仔细考虑咬合和依从性因素后,可以考虑使用透明矫正器
IF 4 4区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 Epub Date: 2025-08-22 DOI: 10.1016/j.jebdp.2025.102197
CARLOS FLORES-MIR DSc (Reviewer)

Article Title and Bibliographic Information

Baneshi et al. Effectiveness of clear orthodontic aligners in correcting maloclusions: A systematic review and meta-analysis. J Evid Base Dent Pract 2025: 102081. Doi: 10.1016/j.jebdp.224.102081.

Source of Funding

Not reported.

Type of Study/Design

Systematic review with meta-analysis of data.
文章标题与书目信息baneshi等。正畸矫正器矫正错牙的有效性:一项系统回顾和荟萃分析。[J]基地凹痕工程学报,2025:102081。Doi: 10.1016 / j.jebdp.224.102081。资金来源未报道。研究类型/设计系统评价,数据荟萃分析。
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引用次数: 0
GTR USING CALCIUM PHOSPHATE GRAFTS MAY ENHANCE CLINICAL ATTACHMENT GAIN IN INTRABONY DEFECTS COMPARED TO FLAP DEBRIDEMENT 与皮瓣清创相比,使用磷酸钙的GTR可提高骨内缺损的临床附着增益
IF 4 4区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 Epub Date: 2025-08-24 DOI: 10.1016/j.jebdp.2025.102196
ROBERT M. EBER (Reviewer)

Article Title and Bibliographic Information

Calcium phosphate grafts combined with guided tissue regeneration in the treatment of periodontal bony defects- a systematic review and meta-analysis. Kouhi M, Yousefi S, Sajadi-Javan SS, Sadeghi E, Savabi O, Shirani M. J Evid Base Dent Pract 2024; 24(4):1-14

Source of Funding

Other: Vice-Chancellery for Research and Technology of Isfahan University of Medical Sciences [grant number: 140181].

Type of Study/Design

Systematic review with meta-analysis of data
磷酸钙移植物联合引导组织再生治疗牙周骨缺损的系统回顾和荟萃分析。Kouhi M, Yousefi S, Sajadi-Javan SS, Sadeghi E, Savabi O, Shirani M. J Evid基地凹模实践2024;24(4):1-14经费来源:伊斯法罕医科大学研究与技术副校长[批准号:140181]。研究类型/设计系统评价,数据荟萃分析
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引用次数: 0
EFFICACY OF BIODENTINE VERSUS MINERAL TRIOXIDE AGGREGATE IN PULPOTOMY FOR PRIMARY TEETH: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS 生物牙牙定与三氧化二矿聚合体在乳牙切髓术中的疗效:随机对照试验的系统回顾和荟萃分析
IF 4 4区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 Epub Date: 2025-08-05 DOI: 10.1016/j.jebdp.2025.102191
KORINA YUN-FAN LU , JENNIFER L. GIBBS , CHENG-YU WU , MARKUS B. BLATZ , XUEHAO MA , MIN-WEN FU , KEVIN SHENG-KAI MA

Background

Mineral trioxide aggregate (MTA) and Biodentine, introduced in the 1990s and 2010, are routinely used in primary teeth pulpotomy, yet their relative success remains unclear.

Objectives

This paper aims to compare Biodentine and MTA efficacy in primary teeth pulpotomy over a 6 to 24-month follow-up, assessing clinical, radiographic, and endodontic outcomes.

Materials and Methods

Randomized controlled trials (RCTs) published from March 2010 to March 2025 comparing the efficacy of Biodentine and MTA in primary teeth pulpotomy with ≥6-month follow-up were included. Their efficacy was determined by clinical and radiographic success rates, as well as 2 endodontic outcomes of root resorption and pulp canal obliteration (PCO). A bivariate and random-effect meta-analysis determined the pooled risk ratios (RRs) of the outcomes.

Results

Eleven RCTs comprising 649 patients and 706 primary teeth were included. Clinical success rates were comparable between Biodentine and MTA at 6 months (RR = 1.00; 95% CI: 0.98-1.02), 12 months (RR = 1.01; 95% CI: 0.97-1.04), 18 months (RR = 0.99; 95% CI: 0.95-1.04), and 24 months (RR = 1.00; 95% CI: 0.94-1.07), with no observed heterogeneity (I² = 0%). Radiographic success rates also showed no significant differences at 6 months (RR = 0.99; 95% CI: 0.97-1.02), 12 months (RR = 1.00; 95% CI: 0.96-1.03), 18 months (RR = 1.01; 95% CI: 0.94-1.09), and 24 months (RR = 1.01; 95% CI: 0.94-1.08). Root resorption and pulp canal obliteration occurred at comparable rates across over 6, 12, and ≥18 months of follow-ups.

Conclusion

Biodentine and MTA exerted comparable success rates in primary teeth pulpotomy at follow-ups of up to 2 years.
三氧化矿物骨料(MTA)和生物牙本质分别于20世纪90年代和2010年被引入,通常用于乳牙切髓术,但它们的相对成功尚不清楚。目的通过6 - 24个月的随访,比较生物牙本质汀和MTA在乳牙切髓术中的疗效,评估临床、影像学和牙髓治疗结果。材料与方法纳入2010年3月至2025年3月发表的随机对照试验(rct),比较Biodentine和MTA在乳牙切髓术中的疗效,随访≥6个月。其疗效由临床和影像学成功率以及根吸收和髓管闭塞(PCO)两种根管治疗结果决定。双变量和随机效应荟萃分析确定了结果的综合风险比(rr)。结果共纳入6组随机对照试验,649例患者,706颗乳牙。临床成功率可比Biodentine与MTA在6个月(RR = 1.00;95%可信区间:0.98 - -1.02),12个月(RR = 1.01;95%可信区间:0.97 - -1.04),18个月(RR = 0.99;95%可信区间:0.95 - -1.04),和24个月(RR = 1.00;95%可信区间:0.94 - -1.07),没有观察到的异质性(我² = 0%)。放射成功率在6个月(RR = 0.99;95% CI: 0.97-1.02)、12个月(RR = 1.00;95% CI: 0.96-1.03)、18个月(RR = 1.01;95% CI: 0.94-1.09)和24个月(RR = 1.01;95% CI: 0.94-1.08)时也无显著差异。在6个月、12个月和≥18个月的随访中,根吸收和髓管闭塞的发生率相当。结论生物牙定和MTA治疗乳牙切髓术后随访2年,成功率相当。
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引用次数: 0
Long-Term Mandibular Advancement Devices for Obstructive Sleep Apnea may Result in Progressive Dental Changes with Minimal Skeletal Effects 用于阻塞性睡眠呼吸暂停的长期下颌推进装置可能导致进行性牙齿改变而骨骼影响最小
IF 4 4区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 Epub Date: 2025-08-22 DOI: 10.1016/j.jebdp.2025.102202
NARAYAN H. GANDEDKAR (Reviewer)

Article Title and Bibliographic Information

Yu M, Ma Y, Gong X, Gao X. Dental and skeletal changes of long-term use of mandibular advancement devices for the treatment of adult obstructive sleep apnea: a systematic review and meta-analysis. J Evid Based Dent Pract. 2024;24(3):1-17. doi:10.1016/j.jebdp.2024.101991.

Source of Funding

Clinical Research Foundation of Peking University School and Hospital of Stomatology (PKUSS-2023CRF106).

Type of Study/Design

Systematic review with meta-analysis.
余明,马勇,龚晓燕,高翔。长期使用下颌推进装置治疗成人阻塞性睡眠呼吸暂停患者的牙齿和骨骼变化:一项系统综述和meta分析。[J] .中文信息学报,2014;24(3):1-17。doi: 10.1016 / j.jebdp.2024.101991。北京大学口腔医学院临床研究基金(pkss - 2023crf106)。研究类型/设计:采用荟萃分析的系统评价。
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引用次数: 0
PULPECTOMY MAY PROVIDE BETTER PATIENT-CENTERED OUTCOMES THAN EXTRACTION OF PULPALLY INVOLVED PRIMARY TEETH 牙髓切除术可能提供更好的以患者为中心的结果比拔牙受累的乳牙
IF 4 4区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 Epub Date: 2025-08-08 DOI: 10.1016/j.jebdp.2025.102189
CHRIS DEERY (Reviewer)

Article Title and Bibliographic Information

Impact Of Pulpectomy Versus Extraction Of Primary Teeth On Patient-Centered Outcomes: A Systematic Review Of Clinical Studies. Vitali FC, Kominami PAA, Andrada AC, Takeshita EM, Massignan C. J Evid Base Dent Pract 2025: [102072] https://doi.org/10.1016/j.jebdp.2024.102072

Source of Funding

Government: Fundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina (FAPESC) - Edital 20/2024 - Brazil, grant number 001.

Type of Study/Design

Systematic review.
摘牙与拔除乳牙对患者预后的影响:临床研究的系统回顾。Vitali FC, Kominami PAA, Andrada AC, Takeshita EM, Massignan C. J Evid Base Dent实践2025:[102072]https://doi.org/10.1016/j.jebdp.2024.102072Source of FundingGovernment: funda o de Amparo Pesquisa e inova o do Estado de Santa Catarina (FAPESC) - Edital 20/2024 -巴西,批准号001。研究类型/设计系统评价。
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引用次数: 0
Levels of Evidence—Grading System 证据分级系统的等级
IF 4 4区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 Epub Date: 2025-11-23 DOI: 10.1016/S1532-3382(25)00131-9
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引用次数: 0
AI MAY SHOW COMPARABLE DIAGNOSTIC ACCURACY TO EXPERTS IN ORAL CANCER DETECTION, BUT EVIDENCE REMAINS LIMITED AND OF LOW CERTAINTY 人工智能可能显示出与口腔癌检测专家相当的诊断准确性,但证据仍然有限且不确定
IF 4 4区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 Epub Date: 2025-08-22 DOI: 10.1016/j.jebdp.2025.102199
OMER WALEED MAJID (Reviewer)

Article Title and Bibliographic Information

Nieri M, Serni L, Clauser T, Paoletti C, Franchi L. Diagnosis of Oral Cancer With Deep Learning. A Comparative Test Accuracy Systematic Review. Oral Dis. 2025 Mar 31. doi:10.1111/odi.15330. Epub ahead of print.

Source of Funding

Not reported.

Type of Study/Design

Systematic review with network meta-analysis.
nieri M, Serni L, Clauser T, Paoletti C, Franchi L.基于深度学习的口腔癌诊断。比较测试精度系统评价。口腔疾病2025年3月31日doi: 10.1111 / odi.15330。打印前Epub。资金来源未报道。研究类型/设计:采用网络荟萃分析的系统评价。
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引用次数: 0
HYDROPHILIC SEALANTS MAY IMPROVE SHORT-TERM RETENTION BUT SHOW SIMILAR CARIES PREVENTION TO HYDROPHOBIC SEALANTS 亲水密封剂可以改善短期固位,但表现出与疏水密封剂相似的防龋效果
IF 4 4区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-01 Epub Date: 2025-08-22 DOI: 10.1016/j.jebdp.2025.102200
LAILA AL  DEHAILAN (Reviewers), NAIF N. ABOGAZALAH, E. ANGELES MARTINEZ-MIER

Article Title and Bibliographic Information

Comparative evaluation of retention and caries preventive effect of hydrophilic and hydrophobic pit and fissure sealants: a systematic review and meta-analysis. Jadhav Sachin Kumar, Zainab Akram, Pg Naveen Kumar, Mahesh R. Khairnar, Andneha Shukla. J Evid Base Dent Pract 2025: [102085]

Source of Funding

Information not available.

Type of Study/Design

Systematic review with meta-analysis of data.
亲水与疏水坑沟密封剂的固位与防龋效果的比较评价:一项系统综述与meta分析。Jadhav Sachin Kumar, Zainab Akram, Pg Naveen Kumar, Mahesh R. Khairnar, Andneha Shukla。[102085]经费来源不明。研究类型/设计系统评价,数据荟萃分析。
{"title":"HYDROPHILIC SEALANTS MAY IMPROVE SHORT-TERM RETENTION BUT SHOW SIMILAR CARIES PREVENTION TO HYDROPHOBIC SEALANTS","authors":"LAILA AL  DEHAILAN (Reviewers),&nbsp;NAIF N. ABOGAZALAH,&nbsp;E. ANGELES MARTINEZ-MIER","doi":"10.1016/j.jebdp.2025.102200","DOIUrl":"10.1016/j.jebdp.2025.102200","url":null,"abstract":"<div><h3>Article Title and Bibliographic Information</h3><div>Comparative evaluation of retention and caries preventive effect of hydrophilic and hydrophobic pit and fissure sealants: a systematic review and meta-analysis. Jadhav Sachin Kumar, Zainab Akram, Pg Naveen Kumar, Mahesh R. Khairnar, Andneha Shukla. J Evid Base Dent Pract 2025: [102085]</div></div><div><h3>Source of Funding</h3><div>Information not available.</div></div><div><h3>Type of Study/Design</h3><div>Systematic review with meta-analysis of data.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 4","pages":"Article 102200"},"PeriodicalIF":4.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145109681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CYTOTOXICITY OF ORTHODONTICS ALIGNERS: AN UMBRELLA REVIEW 正畸矫正器的细胞毒性:综述
IF 4.1 4区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-01 Epub Date: 2025-05-28 DOI: 10.1016/j.jebdp.2025.102168
CATARINA NUNES , BEATRIZ ORNELAS , CARLOS MIGUEL MARTO , ANABELA PAULA , MAFALDA LARANJO , CATARINA MESTRE , RAQUEL TRAVASSOS , INÊS FRANCISCO , FRANCISCO VALE

Objective

This umbrella review aims to determine if clear aligners promote cytotoxic and estrogenic effects.

Methodology

The review was conducted in conformity with the PRISMA statement. A systematic search was carried out in March of 2025 in 5 databases (Medline through PubMed, Web of Science (all databases), Cochrane Library, Embase, and Epistemonikos). All systematic reviews (SRs) that reported the cytotoxicity and/or estrogenicity of orthodontic aligners were included. The quality of the included studies was evaluated using AMSTAR-2 and the degree of overlap was analysed using Corrected Covered Area (CCA).

Results

The literature search resulted in 394 articles. Screening by title and abstract, resulted in 13 articles for full reading, and 4 articles were included in the umbrella review. According to the AMSTAR-2, all reviews were of low quality. The degree of overlap among SRs is high.

Discussion

The included SRs indicate that aligners do not have significant estrogenic/cytotoxic capacity and, even in cases of bisphenol A (BPA) leaching, this occurs at levels well below what is considered toxic. The low quality, high risk of bias, considerable overlap, and significant heterogeneity among the included studies impacts the obtained results.

Conclusion

It is not possible to affirm or refute the presence of estrogenic or cytotoxic effects or the leaching of monomers such as BPA. In the future, it is recommended that studies adopt a more detailed and prolonged analysis of BPA leaching and it is necessary to carry out clinical studies that evaluate the safety and biocompatibility of orthodontic aligners.
目的:本综述旨在确定清除对齐剂是否促进细胞毒性和雌激素作用。方法:按照PRISMA声明进行审查。系统检索于2025年3月在5个数据库(Medline通过PubMed、Web of Science(所有数据库)、Cochrane Library、Embase和Epistemonikos)中进行。所有报道正畸矫正器的细胞毒性和/或雌激素性的系统评价(SRs)都被纳入。使用AMSTAR-2评估纳入研究的质量,使用校正覆盖面积(CCA)分析重叠程度。结果检索到文献394篇。通过标题和摘要筛选,有13篇文章可供全文阅读,4篇文章被纳入总括性综述。根据AMSTAR-2,所有的评论都是低质量的。sr之间的重叠程度很高。所包括的SRs表明,校准剂没有显著的雌激素/细胞毒性能力,即使在双酚A (BPA)浸出的情况下,其水平也远低于被认为有毒的水平。纳入研究的低质量、高偏倚风险、大量重叠和显著异质性影响了获得的结果。结论不可能肯定或反驳雌激素或细胞毒性作用的存在或单体如双酚a的浸出。在未来的研究中,建议对BPA浸出进行更详细和更长期的分析,并有必要开展临床研究,评估正畸矫正器的安全性和生物相容性。
{"title":"CYTOTOXICITY OF ORTHODONTICS ALIGNERS: AN UMBRELLA REVIEW","authors":"CATARINA NUNES ,&nbsp;BEATRIZ ORNELAS ,&nbsp;CARLOS MIGUEL MARTO ,&nbsp;ANABELA PAULA ,&nbsp;MAFALDA LARANJO ,&nbsp;CATARINA MESTRE ,&nbsp;RAQUEL TRAVASSOS ,&nbsp;INÊS FRANCISCO ,&nbsp;FRANCISCO VALE","doi":"10.1016/j.jebdp.2025.102168","DOIUrl":"10.1016/j.jebdp.2025.102168","url":null,"abstract":"<div><h3>Objective</h3><div>This umbrella review aims to determine if clear aligners promote cytotoxic and estrogenic effects.</div></div><div><h3>Methodology</h3><div>The review was conducted in conformity with the PRISMA statement. A systematic search was carried out in March of 2025 in 5 databases (Medline through PubMed, Web of Science (all databases), Cochrane Library, Embase, and Epistemonikos). All systematic reviews (SRs) that reported the cytotoxicity and/or estrogenicity of orthodontic aligners were included. The quality of the included studies was evaluated using AMSTAR-2 and the degree of overlap was analysed using Corrected Covered Area (CCA).</div></div><div><h3>Results</h3><div>The literature search resulted in 394 articles. Screening by title and abstract, resulted in 13 articles for full reading, and 4 articles were included in the umbrella review. According to the AMSTAR-2, all reviews were of low quality. The degree of overlap among SRs is high.</div></div><div><h3>Discussion</h3><div>The included SRs indicate that aligners do not have significant estrogenic/cytotoxic capacity and, even in cases of bisphenol A (BPA) leaching, this occurs at levels well below what is considered toxic. The low quality, high risk of bias, considerable overlap, and significant heterogeneity among the included studies impacts the obtained results.</div></div><div><h3>Conclusion</h3><div>It is not possible to affirm or refute the presence of estrogenic or cytotoxic effects or the leaching of monomers such as BPA. In the future, it is recommended that studies adopt a more detailed and prolonged analysis of BPA leaching and it is necessary to carry out clinical studies that evaluate the safety and biocompatibility of orthodontic aligners.</div></div>","PeriodicalId":48736,"journal":{"name":"Journal of Evidence-Based Dental Practice","volume":"25 3","pages":"Article 102168"},"PeriodicalIF":4.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144534618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EFFICACY OF PHOTOBIOMODULATION THERAPY ON PAIN PERCEPTION DURING LOCAL ANESTHESIA IN CHILDREN: A SYSTEMATIC REVIEW AND META-ANALYSIS 光生物调节治疗对儿童局部麻醉疼痛感知的疗效:系统回顾和荟萃分析
IF 4.1 4区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-01 Epub Date: 2025-04-10 DOI: 10.1016/j.jebdp.2025.102143
MARYAM EMAMI , MEHDI AZIZMOHAMMAD LOOHA , KEITH DA-SILVA , MOHAMMADJAVAD SHIRANI

Objective

This systematic review and meta-analysis is the first to evaluate the impact of photobiomodulation therapy (PBMT) on objective and physiological measures of local anesthesia injection pain in children aged 3-12.

Methods

This review follows the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA) guidelines and is registered in the International Prospective Register of Systematic Reviews (PROSPERO) under the registration number CRD42024549936. A systematic search was conducted in Embase, PubMed, and the Cochrane Library to locate relevant Randomized Clinical Trials (RCTs) between January 2000 to September 2024. Study screening, data extraction, risk of bias evaluation, and certainty of evidence grading were performed independently by 2 reviewers. Meta-analyses focused on the pain assessment using following measures: Wong-Baker Faces Pain Rating Scale (PRS), Sound, Eye, and Motor Scale (SEM), Face, Legs, Activity, Cry, Consolability Scale (FLACC), and heart rate (HR). Sensitivity analyses were conducted using a leave-one-study-out approach to assess the robustness of the findings, while publication bias and heterogeneity were evaluated through established statistical methods.

Results

Out of 1322 identified studies, 7 RCTs met inclusion criteria. PBMT significantly reduced pain, with moderate certainty, as measured by the objective FLACC scale (SMD = −0.41, 95% CI: −0.72, −0.09, P = .011) and the physiological HR method (SMD = −0.50, 95% CI: −0.86, −0.14, P = .006), demonstrating moderate and no heterogeneity, respectively. However, no statistically significant effect was observed on subjective measures using the PRS (SMD = −0.66, 95% CI: −1.63, 0.32, P = .185) and SEM (SMD = 0.18, 95% CI: −1.09, 1.45, P = .780) scales. Five studies had low risk of bias, and GRADE analysis indicated very low to moderate certainty. Funnel plots showed minimal publication bias, except for slight asymmetry in PRS.

Conclusions

PBMT demonstrates potential as a nonpharmacological method to reduce injection pain in children, as reflected in FLACC and HR outcomes. However, no significant effect of PBMT was observed on the SEM scale. Further research is needed to clarify its impact on subjective pain measures (PRS) and to optimize PBMT protocols.
本系统综述和荟萃分析首次评价了光生物调节疗法(PBMT)对3-12岁儿童局麻注射疼痛客观和生理指标的影响。方法本综述遵循系统评价和荟萃分析方案的首选报告项目(PRISMA)指南,并在国际前瞻性系统评价注册库(PROSPERO)注册,注册号为CRD42024549936。系统检索Embase、PubMed和Cochrane图书馆2000年1月至2024年9月的相关随机临床试验(RCTs)。研究筛选、数据提取、偏倚风险评估和证据分级确定性由2位审稿人独立完成。meta分析主要采用以下测量方法进行疼痛评估:Wong-Baker面部疼痛评定量表(PRS)、声音、眼睛和运动量表(SEM)、面部、腿部、活动、哭泣、安慰量表(FLACC)和心率(HR)。敏感性分析采用留一项研究的方法来评估研究结果的稳健性,而发表偏倚和异质性通过既定的统计方法进行评估。结果在1322项纳入的研究中,有7项rct符合纳入标准。通过客观FLACC量表(SMD = - 0.41,95% CI: - 0.72, - 0.09, P = .011)和生理HR法(SMD = - 0.50,95% CI: - 0.86, - 0.14, P = .006)测量,PBMT显著减轻疼痛,具有中等确定性,分别显示中度和无异质性。然而,使用PRS (SMD = −0.66,95% CI:−1.63,0.32,P = .185)和SEM (SMD = 0.18,95% CI:−1.09,1.45,P = .780)量表的主观测量没有统计学上的显著影响。5项研究的偏倚风险较低,GRADE分析显示确定性极低至中等。漏斗图显示,除了PRS有轻微的不对称外,发表偏倚最小。结论spbmt显示了作为一种非药物方法减少儿童注射疼痛的潜力,这反映在FLACC和HR结果中。然而,在扫描电镜量表上没有观察到PBMT的显著影响。需要进一步的研究来阐明其对主观疼痛测量(PRS)的影响,并优化PBMT方案。
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引用次数: 0
期刊
Journal of Evidence-Based Dental Practice
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