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Fathers who experienced childhood maltreatment: aggression and testosterone 经历过童年虐待的父亲:攻击性和睾酮
IF 64.3 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-10-09 DOI: 10.1016/s2215-0366(24)00315-8
Natalia E Fares-Otero, Ingo Schäfer, Eduard Vieta, Soraya Seedat, Sarah L Halligan
No Abstract
无摘要
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引用次数: 0
The regulation of neurotechnology: the neurorights bill in Mexico 神经技术监管:墨西哥神经权利法案
IF 64.3 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-10-08 DOI: 10.1016/s2215-0366(24)00286-4
Karen Herrera-Ferrá, José M Muñoz, Anahiby Becerril, Eric García-López, José Ángel Marinaro, Luis Ricardo Sánchez Hernández, Jesús Alejandro Alonso Otamendi, Alejandra Lagunes Soto Ruiz
No Abstract
无摘要
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引用次数: 0
Ukraine is not alone 乌克兰并非孤立无援
IF 64.3 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-10-04 DOI: 10.1016/s2215-0366(24)00319-5
No Abstract
无摘要
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引用次数: 0
The Lancet Psychiatry Commission on mental health in Ukraine 柳叶刀精神病学委员会关于乌克兰心理健康的报告
IF 64.3 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-10-04 DOI: 10.1016/s2215-0366(24)00241-4
Irina Pinchuk, Bennett L Leventhal, Alisa Ladyk-Bryzghalova, Lars Lien, Yuliia Yachnik, Marisa Casanova Dias, Volodymyr Virchenko, Peter Szatmari, Olena Protsenko, Gary Andrew Chaimowitz, Dan Chisholm, Viktoriia Kolokolova, Anthony P S Guerrero, Stanislav Chumak, Olha Myshakivska, Paul Gerard Robertson, Mark D Hanson, Howard Yee Liu, Livia Joanna De Picker, Marina Kupchik, Norbert Skokauskas
<h2>Section snippets</h2><section><section><h2>Executive summary</h2>The Russian invasion and annexation of eastern Ukraine and Crimea in 2014, along with the ongoing war since February, 2022, have inflicted incalculable damage to Ukraine with many deaths and injuries, massive population displacement, and extensive physical and emotional trauma. These events put an immense strain on the general health-care and mental health-care systems. For many years the mental health-care system in Ukraine was dominated by large psychiatric hospitals and residential</section></section><section><section><h2>Introduction: History and vision for change</h2>Ukraine, the largest democratic country in Europe, has been faced with a perfect storm of challenges. From 1922 to 1991, it was part of the Soviet Union where the mental health-care system was dominated by large psychiatric hospitals and residential institutions focusing almost exclusively on biological therapies. The system was well known for neglect, abuses, and human rights violations.1, 2 As Ukraine emerged from the Soviet era into independence, it underwent massive political, economic, and</section></section><section><section><h2>Part 1: Community-based mental health care and a vision for a new network of Ukrainian mental health-care services</h2>The Commission developed a consensus that Ukraine should develop a network of community-based mental health-care services. A sequence of incremental steps of change should be designed to facilitate progression from the current system towards a community-based mental health-care system.Before 2017, the Ukrainian mental health-care system focused on treatment and tracking (called dispanserisation) of people with severe mental disorders. This strategy was delivered through a network of inpatient</section></section><section><section><h2>Part 2: Training and education of the mental health workforce</h2>A 21st century mental health-care system requires an enabled and skilled multidisciplinary workforce that meets the immediate and emerging needs of the settings in both primary care and specialist mental health-care systems. Nurses, psychologists, allied health professionals, family doctors, and specialists in psychiatry are the core of this mental health workforce. This diverse group requires broad, overlapping capabilities and discipline-specific competencies to function as an integrated and</section></section><section><section><h2>Part 3: Rebuilding mental health research capacity and infrastructure</h2>Historically, Soviet models have dominated Ukrainian mental health research, leaving the country lagging behind European, US, and other models. Since Ukraine gained independence, with the assistance of international colleagues, creative leaders in Ukrainian psychiatry have initiated efforts to remedy these problems. However, the Russian invasion of eastern Ukraine and Crimea in 2014, and the full-scale war in 2022, led to the massive destruction of Ukrainian universiti
章节片段内容提要2014 年俄罗斯入侵和吞并乌克兰东部和克里米亚,以及自 2022 年 2 月以来持续不断的战争,给乌克兰造成了无法估量的损失,导致多人死伤、大量人口流离失所,以及广泛的身体和精神创伤。这些事件给普通保健和精神保健系统造成了巨大压力。多年来,乌克兰的精神卫生保健系统一直由大型精神病医院和寄宿医院主导:历史与变革愿景乌克兰作为欧洲最大的民主国家,一直面临着一场完美的挑战风暴。从 1922 年到 1991 年,乌克兰一直是苏联的一部分,当时的精神卫生保健系统主要由大型精神病医院和寄宿机构组成,几乎完全以生物疗法为主。1, 2 随着乌克兰从苏联时代独立出来,它经历了大规模的政治、经济和社会变革:委员会达成了一项共识,即乌克兰应建立一个以社区为基础的心理健康服务网络。在 2017 年之前,乌克兰的精神卫生保健系统侧重于对严重精神障碍患者的治疗和跟踪(称为 "解散")。这一战略是通过一个住院病人网络来实施的。第 2 部分:精神卫生工作者队伍的培训和教育21 世纪的精神卫生保健系统需要一支有能力、有技能的多学科队伍,以满足基层医疗和专科精神卫生保健系统的即时和新出现的需求。护士、心理学家、专职医疗人员、家庭医生和精神病学专家是这支心理健康工作队伍的核心。这支多元化的队伍需要广泛、重叠的能力和特定学科的能力,才能作为一支综合的队伍发挥作用。自乌克兰获得独立以来,在国际同行的协助下,乌克兰精神病学领域富有创造力的领导者已经开始努力纠正这些问题。然而,2014 年俄罗斯入侵乌克兰东部和克里米亚以及 2022 年的全面战争导致乌克兰的大学和研究机构遭到大规模破坏。其中包括对缺陷的关注、对法律行为能力的限制以及将精神障碍定为刑事犯罪。这些都加剧了对精神疾病患者的羞辱,并使他们被视为二等公民。尽管乌克兰第一夫人和许多非政府组织等都在提高人们对战争期间预防精神健康损害的认 识,但与战争相关的严重精神创伤的可能性仍在增加。乌克兰政府的《概念说明》(2017 年)7 和《行动计划》(2021 年)107 为乌克 兰提出了一个截然不同的、更具时代性的愿景,包括与国际人权接轨的立法、新的精神 健康促进和服务。设想中的服务网络包括:由非专业人员在社区提供基本的社会心理支持和简短的心理干预;在基层管理常见的精神障碍。
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引用次数: 0
Building a recovery-oriented mental health system in Ukraine: lessons from implementation science 在乌克兰建立以康复为导向的心理健康体系:从实施科学中汲取的经验教训
IF 64.3 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-10-04 DOI: 10.1016/s2215-0366(24)00289-x
Matthew Menear
No Abstract
无摘要
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引用次数: 0
Ukrainian mental health in transition: from totalitarianism towards a modern mental health system 转型期的乌克兰心理健康:从极权主义走向现代心理健康体系
IF 64.3 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-10-04 DOI: 10.1016/s2215-0366(24)00325-0
Orest Suvalo, Vsevolod Borovets
No Abstract
无摘要
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引用次数: 0
The Commission on mental health in Ukraine: areas for development 乌克兰心理健康委员会:有待发展的领域
IF 64.3 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-10-04 DOI: 10.1016/s2215-0366(24)00312-2
Kostyantyn Dumchev, Vitalii Klymchuk
No Abstract
无摘要
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引用次数: 0
NMDAR1 autoantibodies as potential biomarkers for schizophrenia phenotyping. NMDAR1自身抗体作为精神分裂症表型的潜在生物标记物。
IF 64.3 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-10-01 DOI: 10.1016/s2215-0366(24)00282-7
Niels Hansen,Daniel Luedecke,Hannah Benedictine Maier,Alexandra Neyazi,Dirk Fitzner,Jens Wiltfang,Berend Malchow
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引用次数: 0
Psychotropic drug prescribing before and during the COVID-19 pandemic among people with depressive and anxiety disorders: a multinational network study. 抑郁症和焦虑症患者在 COVID-19 大流行之前和期间的精神药物处方:一项多国网络研究。
IF 30.8 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-10-01 Epub Date: 2024-09-03 DOI: 10.1016/S2215-0366(24)00245-1
Hao Luo, Yi Chai, Sijia Li, Wallis C Y Lau, Carmen Olga Torre, Joseph Hayes, Ivan C H Lam, Xiaoyu Lin, Can Yin, Stephen Fortin, Dave M Kern, Dong Yun Lee, Rae Woong Park, Jae-Won Jang, Celine S L Chui, Jing Li, Sarah Seager, Kenneth K C Man, Ian C K Wong

Background: People with mental health conditions were potentially more vulnerable than others to the neuropsychiatric effects of the COVID-19 pandemic and the global efforts taken to contain it. The aim of this multinational study was to examine the changes in psychotropic drug prescribing during the pandemic among people with depressive and anxiety disorders.

Methods: This study included electronic medical records and claims data from nine databases in six countries (France, Germany, Italy, the UK, South Korea, and the USA) of patients with a diagnosis of depressive or anxiety disorders between 2016 and 2021. The outcomes were monthly prevalence rates of antidepressant, antipsychotic, and anxiolytic drug prescribing. The associations between the pandemic and psychotropic drug prescribing were examined with interrupted time series analyses for the total sample and stratified by sex and age group. People with lived experience were not involved in the research and writing process.

Findings: Between Jan 1, 2016 and Dec 31, 2020, an average of 16 567 914 patients with depressive disorders (10 820 956 females [65·31%] and 5 746 958 males [34·69%]) and 15 988 451 patients with anxiety disorders (10 688 788 females [66·85%] and 5 299 663 males [33·15%]) were identified annually. Most patients with depressive disorders and anxiety disorders were aged 45-64 years. Ethnicity data were not available. Two distinct trends in prescribing rates were identified. The first pattern shows an initial surge at the start of the pandemic (eg, antipsychotics among patients with depressive disorders in MDCD_US (rate ratio [RR] 1·077, 95% CI 1·055-1·100), followed by a gradual decline towards the counterfactual level (RR 0·990, 95% CI 0·988-0·992). The second pattern, observed in four databases for anxiolytics among patients with depressive disorders and two for antipsychotics among patients with anxiety disorders, shows an immediate increase (eg, antipsychotics among patients with anxiety disorders in IQVIA_UK: RR 1·467, 95% CI 1·282-1·675) without a subsequent change in slope (RR 0·985, 95% CI 0·969-1·003). In MDCD_US and IQVIA_US, the anxiolytic prescribing rate continued to increase among patients younger than 25 years for both disorders.

Interpretation: The study reveals persistently elevated rates of psychotropic drug prescriptions beyond the initial phase of the pandemic. These findings underscore the importance of enhanced mental health support and emphasise the need for regular review of psychotropic drug use among this patient group in the post-pandemic era.

Funding: University Grants Committee, Research Grants Council, The Government of the Hong Kong Special Administrative Region.

背景:患有精神疾病的人可能比其他人更容易受到 COVID-19 大流行和全球遏制 COVID-19 的努力所造成的神经精神影响。这项多国研究的目的是调查大流行期间抑郁症和焦虑症患者精神药物处方的变化情况:本研究纳入了六个国家(法国、德国、意大利、英国、韩国和美国)九个数据库中 2016 年至 2021 年期间诊断为抑郁或焦虑症患者的电子病历和索赔数据。研究结果是抗抑郁药、抗精神病药和抗焦虑药的每月处方率。通过对全部样本以及按性别和年龄组进行分层的间断时间序列分析,研究了大流行与精神药物处方之间的关联。有生活经验的人没有参与研究和撰写过程:在 2016 年 1 月 1 日至 2020 年 12 月 31 日期间,平均每年发现 16 567 914 名抑郁障碍患者(女性 10 820 956 名[65-31%],男性 5 746 958 名[34-69%])和 15 988 451 名焦虑障碍患者(女性 10 688 788 名[66-85%],男性 5 299 663 名[33-15%])。大多数抑郁障碍和焦虑障碍患者的年龄在 45-64 岁之间。种族数据不详。在处方率方面发现了两种明显的趋势。第一种模式显示了大流行开始时的激增(例如,MDCD_US 抑郁症患者中的抗精神病药物(比率比 [RR] 1-077,95% CI 1-055-1-100),随后逐渐下降到反事实水平(RR 0-990,95% CI 0-988-0-992)。第二种模式在四个数据库中观察到,抑郁症患者使用抗焦虑药,两个数据库中观察到焦虑症患者使用抗精神病药,结果显示立即增加(例如,在 IQVIA_UK 中,焦虑症患者使用抗精神病药,RR 1-467,95% CI 0-988-0-992):RR 1-467,95% CI 1-282-1-675),但随后的斜率没有变化(RR 0-985,95% CI 0-969-1-003)。在 MDCD_US 和 IQVIA_US 中,25 岁以下两种疾病患者的抗焦虑药处方率持续上升:研究显示,精神药物处方率在大流行初期之后持续上升。这些发现强调了加强精神健康支持的重要性,并强调了在疫情过后定期检查这一患者群体中精神药物使用情况的必要性:大学教育资助委员会、研究资助局、香港特别行政区政府。
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引用次数: 0
Dr Alfiee: Transforming lives for people of colour. 阿尔菲博士改变有色人种的生活。
IF 64.3 1区 医学 Q1 PSYCHIATRY Pub Date : 2024-10-01 DOI: 10.1016/s2215-0366(24)00284-0
Jules Morgan
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引用次数: 0
期刊
Lancet Psychiatry
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