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Acute paraesophageal hernia with gastric volvulus. Results of surgical treatment: a systematic review and meta-analysis 急性食管旁疝伴胃扭转。手术治疗的结果:系统回顾和荟萃分析
IF 8 1区 医学 Q1 EMERGENCY MEDICINE Pub Date : 2025-05-19 DOI: 10.1186/s13017-025-00617-3
Carlos Manterola, Enrique Biel, Josue Rivadeneira, Manuel Pera, Luis Grande
Acute gastric volvulus (AGV), is an uncommon complication of large paraesophageal hernias (PEH), resulting in closed-loop obstruction that may lead to incarceration and strangulation. The aim of this study was to summarize the evidence on clinical characteristics, surgical treatment, postoperative complications (POC), recurrence, and 30-day mortality (30DM), in patients undergoing surgery for AGV secondary to PEH. A systematic review including studies on AGV secondary to PEH was conducted. Searches were performed in WoS, Embase, Medline, Scopus, BIREME-BV and SciELO. Primary outcomes included POC, 30DM and recurrence. Secondary outcomes comprised publication date, study origin and design, number of patients, volvulus type, hospital stay length, treatments; and methodological quality (MQ) of studies assessed using MInCir-T and MInCir-Pr2 scales. Descriptive statistics, weighted averages (WA), least squares logistic regression for comparisons, and meta-analysis of POC prevalence and HM were applied. Of 1049 studies 171 met selection criteria, encompassing 15,178 patients. The WA age of patients was 75.3 ± 13.9 years, with 51.3% female. Most studies originated from USA (31.6%), with 52.6% published in the last decade. The WA of hospital stay was 7.9 ± 5.3 days. Among patients, 32.0% experienced POC, 7.6% required reinterventions and HM was 5.7%. MQ scores averaged 8.9 ± 2.3 (MInCir-T) and 13.4 ± 5.4 (MInCir-Pr2). When comparing 1990–2014 and 2015–2024 periods, there were significant differences in age, reinterventions, readmissions and recurrence rates. Despite surgical and resuscitative advancements, AGV prognosis remains poor, with high POC rates, prolonged hospitalization and significant 30DM. These findings emphasize the importance of early diagnosis and timely intervention for acute PEH to improve surgical outcomes.
急性胃扭转(AGV)是大食道旁疝(PEH)的一种罕见并发症,导致闭环阻塞,可能导致嵌顿和绞窄。本研究的目的是总结PEH继发AGV手术患者的临床特征、手术治疗、术后并发症(POC)、复发和30天死亡率(30DM)的证据。对继发于PEH的AGV进行了系统综述。在WoS、Embase、Medline、Scopus、BIREME-BV和SciELO中进行检索。主要结局包括POC、30DM和复发。次要结局包括发表日期、研究来源和设计、患者数量、肠扭转类型、住院时间、治疗方法;以及使用minir - t和minir - pr2量表评估的研究的方法学质量(MQ)。采用描述性统计、加权平均(WA)、最小二乘逻辑回归进行比较,并对POC患病率和HM进行meta分析。在1049项研究中,171项符合选择标准,包括15178名患者。患者WA年龄为75.3±13.9岁,女性占51.3%。大多数研究来自美国(31.6%),其中52.6%的研究发表于近10年。住院时间WA为7.9±5.3 d。32.0%的患者经历了POC, 7.6%的患者需要再干预,而HM为5.7%。MQ评分平均为8.9±2.3 (minir - t)和13.4±5.4 (minir - pr2)。1990-2014年与2015-2024年期间比较,年龄、再干预、再入院率和复发率均有显著差异。尽管手术和复苏取得了进展,但AGV预后仍然很差,POC率高,住院时间长,30DM明显。这些发现强调了早期诊断和及时干预急性PEH对改善手术效果的重要性。
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引用次数: 0
Meta-analysis of the optimal needle length and decompression site for tension pneumothorax and consensus recommendations on current ATLS and ETC guidelines. 张力性气胸最佳针长和减压部位的meta分析,以及对当前ATLS和ETC指南的一致建议。
IF 8 1区 医学 Q1 EMERGENCY MEDICINE Pub Date : 2025-05-19 DOI: 10.1186/s13017-025-00613-7
Suhaib J S Ahmad,Jason R Degiannis,Marion Head,Ahmed R Ahmed,Edgar Gelber,Sherif Hakky,Armin Kieser,Martin Müller,John Darling,Dominik A Jakob,Ioannis Panagiotis Kyriazidis,Konstantinos Degiannis,Patrick Dorn,Anil Lala,Christopher Bowman,Danielle Wilkinson,Graham Whiteley,Umair Hassan,Younis Mohamed,Kai Hui Loo,Ynyr Dewi Davies,Richard Egan,Sjaak Pouwels,Amber Coulthard,Lowri Churchill,Kiran Bhavra,Christopher Bailey,Ian Johnson,Ifan Rees,Dafydd Williams,Shahab Hajibandeh,Wah Yang,Christian Peter Subbe,Amy Owen,David Rawaf,Ameer Khamise,Ali Waleed Khalid,Chetan Parmar,J Agustin Soler,Miriam Khalil,Ata Mohajer-Bastami,Sarah Moin,Rami Archid,Mohamed Abdulmajed,Rosalind Jones,Vignesh Balasubaramaniam,Rawa Al-Salihi,Arran Shoker,Mei-Ju Hwang,Olga Griffiths,Sushil Pandey,Lucy Lee-Smith,Aristomenis K Exadaktylos
BACKGROUNDTension pneumothorax (TP) is a life-threatening condition. The immediate recommended management is needle decompression (ND), followed by the insertion of an intercostal chest drain. The European Trauma Course (ETC) and the Advanced Trauma Life Support (ATLS) guidelines differ on needle size and decompression site, creating clinical uncertainty. This meta-analysis aims to explore the optimal approach for emergency needle decompression in TP.METHODSThis meta-analysis followed the PRISMA 2020 guidelines. It included English-language RCTs, cohort, case-control, cross-sectional studies, and case series with more than six patients. Studies on adults undergoing needle decompression therapy for TP or with chest wall thickness measurements were included. Ovid MEDLINE, Embase, and Web of Science databases were searched until May 31, 2024. Data were extracted, assessed for quality using OCEBM and GRADE, and analyzed using SPSS and OpenMeta with random-effects models.PRIMARY OUTCOMEneedle decompression failure rate.SECONDARY OUTCOMESpatient demographics, cannula size, and chest wall thickness comparisons.RESULTSThis review analyzed 51 studies on needle decompression for TP, with a weighted mean patient age of 36.67 years. Radiological data from 24 studies (n = 8046) indicated a 32.84% failure rate for needle penetration into the pleural cavity (I2: 99.72%). Increased needle length reduced failure rates by 7.76% per cm. No significant differences in chest wall thickness between genders were observed (T-test, p = 0.77), but thickness at the 5th anterior axillary line (5AAL) and 5th midaxillary line (5MAL) was less than at the 2nd midclavicular line (2MCL). Injury rates were higher at 5AAL than 5MAL, with strong positive correlations between needle length and injury at these sites (0.88, 0.91).CONCLUSIONBased on our meta-analysis, a 7 cm needle may be appropriate for decompression of right-sided tension pneumothorax at either the 5th intercostal space along the midaxillary line or the 2nd intercostal space along the midclavicular line. For left-sided cases, given the potential risk of cardiac injury, the 2nd midclavicular line is a safer option. However, these recommendations should be interpreted with caution due to considerable heterogeneity among the included studies, potential risk of bias, and variability in measurement techniques. Clinical decisions should always be individualized, taking into account patient-specific factors.
背景:张力性气胸(TP)是一种危及生命的疾病。立即推荐的处理方法是针减压(ND),然后插入肋间胸腔引流管。欧洲创伤课程(ETC)和高级创伤生命支持(ATLS)指南在针的大小和减压部位上存在差异,造成临床不确定性。本荟萃分析旨在探讨急诊TP针减压的最佳方法。方法本荟萃分析遵循PRISMA 2020指南。它包括英语随机对照试验、队列、病例对照、横断面研究和6例以上患者的病例系列。研究对象包括接受TP针减压治疗或胸壁厚度测量的成人。Ovid MEDLINE, Embase和Web of Science数据库被检索到2024年5月31日。提取数据,使用OCEBM和GRADE评估质量,并使用SPSS和OpenMeta随机效应模型进行分析。主要结局:针头减压失败率。次要结局:患者人口统计学、插管大小和胸壁厚度比较。结果本综述分析了51项关于TP针减压的研究,加权平均患者年龄为36.67岁。24项研究(n = 8046)的放射学资料显示,胸膜穿刺失败率为32.84% (I2: 99.72%)。增加针长,每厘米故障率降低7.76%。两性胸壁厚度差异无统计学意义(t检验,p = 0.77),但第5腋前线(5AAL)和第5腋中线(5MAL)胸壁厚度小于第2锁骨中线(2MCL)胸壁厚度。5AAL损伤率高于5MAL,针长与这些部位的损伤呈显著正相关(0.88,0.91)。结论根据我们的meta分析,在沿腋中线的第5肋间隙或沿锁骨中线的第2肋间隙进行右侧紧张性气胸减压,7 cm针都是合适的。对于左侧的病例,考虑到心脏损伤的潜在风险,第二锁骨中线是一个更安全的选择。然而,由于纳入的研究存在相当大的异质性、潜在的偏倚风险和测量技术的可变性,这些建议应谨慎解释。临床决策应始终是个体化的,考虑到患者的具体因素。
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引用次数: 0
Clinical outcomes of rib fracture stabilization and conservative treatment in a high-volume Asian trauma center: a propensity score-matched retrospective study 亚洲一个大容量创伤中心肋骨骨折稳定和保守治疗的临床结果:倾向评分匹配的回顾性研究
IF 8 1区 医学 Q1 EMERGENCY MEDICINE Pub Date : 2025-05-19 DOI: 10.1186/s13017-025-00620-8
Chia-Cheng Kao, Ke-Cheng Chen, Xu-Heng Chiang, Jen-Hao Chuang, Chao-Wen Lu, Wei-Ling Hsiao, Tzu-Hsin Lin, Hsien-Chi Liao
Rib fractures are common chest wall injuries with conservative treatment and surgical stabilization of rib fractures (SSRF) as treatment options. We retrospectively compared the efficacy and long-term prognosis of conservative treatment and SSRF as treatment options for rib fractures. This retrospective study was conducted at a single trauma center in Taiwan. The study population comprised patients with rib fractures who underwent conservative treatment or SSRF at the National Taiwan University Hospital between 2017 and 2022. We analyzed the outcomes between the operative and non-operative groups, including the length of intensive care unit and hospital stays, pain scales at admission and follow-up, and post-operative complication rates. Of the 217 patients with rib fractures in this study, 103 received SSRF, and 114 received conservative treatment. Patients in the operative group had worse consciousness statuses and higher injury severity scores than those in the non-operative group. In addition, patients in the operative group had more preoperative chest complications than those in the non-operative group. Regarding outcomes and long-term prognoses, patients in the operative group had longer intensive care unit and hospital stays than those in the non-operative group; however, patients in the operative group had better recovery quality than those in the non-operative group. Our study showed that, in patients who meet the surgical indications, SSRF is an effective and safe way to relieve acute pain after thoracic injury and achieve better recovery and quality of life after surgical intervention.
肋骨骨折是常见的胸壁损伤,保守治疗和肋骨骨折手术稳定(SSRF)是治疗选择。我们回顾性比较了保守治疗和SSRF治疗肋骨骨折的疗效和长期预后。本研究在台湾单一创伤中心进行。研究人群包括2017年至2022年间在国立台湾大学医院接受保守治疗或SSRF的肋骨骨折患者。我们分析了手术组和非手术组之间的结果,包括重症监护病房和住院时间,入院和随访时的疼痛量表,以及术后并发症发生率。在本研究的217例肋骨骨折患者中,103例接受SSRF治疗,114例接受保守治疗。手术组患者意识状态差,损伤严重程度评分高于非手术组。此外,手术组患者术前胸部并发症发生率高于非手术组。关于结局和长期预后,手术组患者的重症监护病房和住院时间比非手术组更长;但手术组患者恢复质量优于非手术组。我们的研究表明,在符合手术指征的患者中,SSRF是一种有效且安全的方法,可以缓解胸椎损伤后的急性疼痛,并在手术干预后获得更好的恢复和生活质量。
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引用次数: 0
The influence between frailty, sarcopenia and physical status on mortality in patients undergoing emergency laparotomy 虚弱、肌肉减少和身体状况对急诊剖腹手术患者死亡率的影响
IF 8 1区 医学 Q1 EMERGENCY MEDICINE Pub Date : 2025-04-30 DOI: 10.1186/s13017-025-00588-5
May Myat Thu, Hwei Jene Ng, Susan Moug
Frailty and sarcopenia have been independently shown to predict mortality in emergency laparotomy (EmLap), and both can be indicative of poor physical status. We aim to assess the prevalence of frailty, sarcopenia, and physical status in EmLap and explore the relationship between these factors and 30-day, 90-day and 1-year mortality. Retrospective analysis was performed on prospectively maintained Emergency Laparotomy and Laparoscopic Scottish Audit (ELLSA) database (2017–2019) which included patients ≥ 18 years who underwent EmLap. Clinical frailty scale (CFS) was used to classify frailty (score ≥ 4 as frail). Sarcopenia was assessed using total psoas index (TPI). Poor physical status (PPS) was defined by American Society of Anaesthesiologists physical status classification (ASA) ≥ 4. Binary logistic regression and fisher’s exact tests were used for statistical analysis. 215 patients were included in the study, with 57.2% female and median age of 64 years. Frailty was present in 17.2%, sarcopenia in 25.1% and 14.4% had PPS; 3.3% had all three factors. Frail patients had significantly higher risk for 30-day (p = 0.003), 90-day (p = 0.006) and 1-year mortality (p = 0.032). Patients with poor physical status also showed significantly higher mortality at 30-day (p < 0.001), 90-day (p < 0.001) and 1-year (p = 0.001). Sarcopenic patients did not show significant differences in mortality risks up to 1 year. Patients with all three factors had significantly higher 30-day (p = 0.003), 90-day (p = 0.046) and 1-year mortality (p = 0.108) compared to patients who had none of the factors. Frailty, sarcopenia, and PPS are prevalent in EmLap. Frailty and PPS were independently associated with short and long-term mortality, but not sarcopenia. While overlap exists between three factors, more research is required to understand the complex interplay.
虚弱和肌肉减少症已被独立证明可以预测急诊剖腹手术(EmLap)的死亡率,两者都可能表明身体状况不佳。我们的目的是评估EmLap患者的虚弱、肌肉减少症和身体状况的患病率,并探讨这些因素与30天、90天和1年死亡率之间的关系。回顾性分析前瞻性维持的急诊剖腹手术和腹腔镜苏格兰审计(ELLSA)数据库(2017-2019),其中包括≥18岁接受EmLap的患者。采用临床虚弱量表(CFS)对虚弱进行分类(评分≥4分为虚弱)。用总腰肌指数(TPI)评估肌肉减少症。不良生理状态(PPS)被美国麻醉医师协会生理状态分类(ASA)定义为≥4。采用二元逻辑回归和fisher精确检验进行统计分析。215例患者纳入研究,其中57.2%为女性,中位年龄64岁。虚弱者占17.2%,肌肉减少者占25.1%,PPS患者占14.4%;3.3%的人三个因素都有。体弱多病患者30天(p = 0.003)、90天(p = 0.006)和1年死亡率(p = 0.032)均显著增高。身体状况较差的患者在30天(p < 0.001)、90天(p < 0.001)和1年(p = 0.001)的死亡率也明显较高。骨骼肌减少症患者在1年内的死亡风险没有显着差异。与没有上述三种因素的患者相比,有上述三种因素的患者的30天(p = 0.003)、90天(p = 0.046)和1年死亡率(p = 0.108)均显著高于无上述三种因素的患者。虚弱、肌肉减少症和PPS在EmLap中普遍存在。虚弱和PPS与短期和长期死亡率独立相关,但与肌肉减少症无关。虽然三个因素之间存在重叠,但需要更多的研究来了解复杂的相互作用。
{"title":"The influence between frailty, sarcopenia and physical status on mortality in patients undergoing emergency laparotomy","authors":"May Myat Thu, Hwei Jene Ng, Susan Moug","doi":"10.1186/s13017-025-00588-5","DOIUrl":"https://doi.org/10.1186/s13017-025-00588-5","url":null,"abstract":"Frailty and sarcopenia have been independently shown to predict mortality in emergency laparotomy (EmLap), and both can be indicative of poor physical status. We aim to assess the prevalence of frailty, sarcopenia, and physical status in EmLap and explore the relationship between these factors and 30-day, 90-day and 1-year mortality. Retrospective analysis was performed on prospectively maintained Emergency Laparotomy and Laparoscopic Scottish Audit (ELLSA) database (2017–2019) which included patients ≥ 18 years who underwent EmLap. Clinical frailty scale (CFS) was used to classify frailty (score ≥ 4 as frail). Sarcopenia was assessed using total psoas index (TPI). Poor physical status (PPS) was defined by American Society of Anaesthesiologists physical status classification (ASA) ≥ 4. Binary logistic regression and fisher’s exact tests were used for statistical analysis. 215 patients were included in the study, with 57.2% female and median age of 64 years. Frailty was present in 17.2%, sarcopenia in 25.1% and 14.4% had PPS; 3.3% had all three factors. Frail patients had significantly higher risk for 30-day (p = 0.003), 90-day (p = 0.006) and 1-year mortality (p = 0.032). Patients with poor physical status also showed significantly higher mortality at 30-day (p < 0.001), 90-day (p < 0.001) and 1-year (p = 0.001). Sarcopenic patients did not show significant differences in mortality risks up to 1 year. Patients with all three factors had significantly higher 30-day (p = 0.003), 90-day (p = 0.046) and 1-year mortality (p = 0.108) compared to patients who had none of the factors. Frailty, sarcopenia, and PPS are prevalent in EmLap. Frailty and PPS were independently associated with short and long-term mortality, but not sarcopenia. While overlap exists between three factors, more research is required to understand the complex interplay.","PeriodicalId":48867,"journal":{"name":"World Journal of Emergency Surgery","volume":"31 6 1","pages":""},"PeriodicalIF":8.0,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143889623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in frailty status and discharge destination post emergency laparotomy 急诊剖腹手术后虚弱状态和出院目的地的变化
IF 8 1区 医学 Q1 EMERGENCY MEDICINE Pub Date : 2025-04-25 DOI: 10.1186/s13017-025-00612-8
Hwei Jene Ng, Nicholas J. W. Rattray, Tara Quasim, Susan J. Moug
Pre-operative frailty adversely affects morbidity and mortality after emergency laparotomy (EmLap), especially in older adults (65 years and above). Little is known about frailty after EmLap. We explored the change in frailty status from pre- to post-EmLap and any influence on discharge destination. EmLap patients aged ≥ 65years from an acute surgical site were recruited from May 2022 to April 2023. Prospective data collection included demographics, frailty, mortality and discharge destination. Frailty was assessed using the Rockwood Clinical Frailty Scale at pre-EmLap and day-90 post-EmLap (< 4 as non-frail, 4 as pre-frail and > 4 as frail). EmLap patients with no 90-day follow-up were excluded. A p-value of < 0.05 was considered significant. 63 EmLap patients were included in the study. The median age was 75 years (range 65–91 years) with 36 (57.1%) females. Eleven (17.5%) were living with frailty pre-EmLap, and 10 (15.9%) developed new frailty by day-90 post-EmLap. Pre-EmLap, all patients came from home with 20.6% of the frail and pre-frail group having a package of care service (POC) in place. On 90-day post-EmLap, 1 was still an inpatient but 25.8% had a change in discharge destination: care home (n = 1), home with new POC (n = 2) and home with increased POC (n = 13). Of the 16 patients with change of discharge destination, 9 (56.3%) were frail pre-EmLap. There was a significant association between pre-EmLap frailty and change in home circumstances on discharge (p < 0.00001). Emergency surgery can increase a patient’s frailty status and significantly increases care requirements and social support after hospital discharge. Frailty assessment needs to be performed before and after admission in all EmLap patients to improve post-EmLap care planning and patient expectations.
术前虚弱对急诊剖腹手术(EmLap)后的发病率和死亡率有不利影响,尤其是在老年人(65岁及以上)中。人们对EmLap之后的虚弱知之甚少。我们探讨了emlap前后患者虚弱状态的变化及其对出院目的地的影响。从2022年5月至2023年4月招募年龄≥65岁的急性手术部位EmLap患者。前瞻性数据收集包括人口统计、虚弱、死亡率和出院目的地。在emlap前和emlap后第90天使用Rockwood临床虚弱量表评估虚弱程度(4分虚弱)。没有90天随访的EmLap患者被排除在外。p值< 0.05被认为是显著的。63例EmLap患者纳入研究。年龄中位数为75岁(65 ~ 91岁),女性36例(57.1%)。11例(17.5%)患者在emlap治疗前存在虚弱,10例(15.9%)患者在emlap治疗后第90天出现新的虚弱。在实施emlap之前,所有患者都来自家中,20.6%的体弱和体弱前期患者有一揽子护理服务(POC)。在emlap后90天,1名患者仍然是住院患者,但25.8%的患者出院目的地发生了变化:养老院(n = 1),新POC的家庭(n = 2)和POC增加的家庭(n = 13)。在16例改变出院目的地的患者中,9例(56.3%)为emlap前虚弱患者。emlap前的虚弱与出院时家庭环境的改变有显著的相关性(p < 0.00001)。急诊手术可以增加病人的虚弱状态,并显著增加出院后的护理需求和社会支持。所有EmLap患者入院前和入院后需要进行虚弱评估,以改善EmLap后的护理计划和患者期望。
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引用次数: 0
Management of acute mesenteric ischaemia in adult patients: a systematic review and meta-analysis 成年患者急性肠系膜缺血的治疗:系统回顾和荟萃分析
IF 8 1区 医学 Q1 EMERGENCY MEDICINE Pub Date : 2025-04-24 DOI: 10.1186/s13017-025-00614-6
Annika Reintam Blaser, Merli Koitmäe, Kaspar F. Bachmann, Paola De Gaetano, Ele Kiisk, Kaja-Triin Laisaar, Simone Piva, Klaus Stahl, Kadri Tamme, Stefan Acosta
Guidance on managing acute mesenteric ischaemia (AMI) is largely based on expert opinion and retrospective studies pooling different subtypes of AMI. In clinical practice, management strategy is often selected based on the patient’s severity of illness, whereas randomized controlled trials or even adjusted analyses comparing different strategies are rarely available. We aimed to perform a systematic review and meta-analysis on the effect of different management options when adjusted for the baseline severity of illness. A literature search was performed in PubMed, the Cochrane Library, Web of Science and Scopus. Studies recruiting patients after the year 2000, assessing at least 10 adult patients with reliably confirmed AMI, and comparing different management approaches were considered for inclusion. Thirteen study questions on different management strategies in different subtypes of AMI were formulated a priori. We included studies reporting results of adjusted analyses or reporting any variables reflecting the severity of illness in both study groups under comparison. A total of 3324 publications were identified, 321 were selected for full-text review and 31 included in the review and analysis. Most of the studies comparing different management strategies of AMI did not report the severity of illness in the groups under comparison. Any variable that could be considered to reflect the severity of illness was reported in 26 studies. The available data only allowed one meta-regression analysis comparing initial endovascular revascularization versus open surgery in arterial occlusive AMI, including four studies that reported white blood cell count and lactate. The results indicate that the significant advantage of the endovascular approach suggested in the crude analysis may be abolished when adjusting for the severity of the illness. Narrative summaries and raw data are presented for other research questions. The severity of illness plays an important role in the selection of management strategy and largely determines the outcome of any treatment, yet is generally not considered in available studies assessing the management of AMI. There is a major gap in the literature precluding appropriate analyses on treatment effects. Future studies should report subtypes of AMI and the severity of illness for each group. PROSPERO CRD42024568497, date of registration: July 20th, 2024
急性肠系膜缺血(AMI)的治疗指南主要基于专家意见和回顾性研究,汇集了不同的AMI亚型。在临床实践中,通常根据患者病情的严重程度选择管理策略,而比较不同策略的随机对照试验甚至调整分析很少。我们的目的是对不同治疗方案的效果进行系统回顾和荟萃分析,并根据疾病的基线严重程度进行调整。在PubMed、Cochrane图书馆、Web of Science和Scopus中进行了文献检索。研究招募2000年后的患者,评估至少10例可靠确诊AMI的成年患者,并比较不同的治疗方法。针对AMI不同亚型的不同管理策略,先验地制定了13个研究问题。我们纳入了报告调整分析结果的研究,或报告了反映两组比较中疾病严重程度的任何变量的研究。共鉴定出3324篇文献,其中321篇入选全文综述,31篇纳入综述分析。大多数比较AMI不同治疗策略的研究没有报道被比较组的疾病严重程度。26项研究报告了任何可以被认为反映疾病严重程度的变量。现有数据仅允许一项荟萃回归分析,比较动脉闭塞性AMI的初始血管内重建术与开放手术,包括四项报告白细胞计数和乳酸的研究。结果表明,当调整疾病的严重程度时,在粗分析中提出的血管内入路的显著优势可能会被取消。叙述摘要和原始数据提出了其他研究问题。疾病的严重程度在治疗策略的选择中起着重要作用,在很大程度上决定了任何治疗的结果,但在评估AMI治疗的现有研究中通常没有考虑到疾病的严重程度。文献中有一个主要的空白,妨碍了对治疗效果的适当分析。未来的研究应该报告AMI的亚型和每组的疾病严重程度。PROSPERO CRD42024568497,注册日期:2024年7月20日
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引用次数: 0
Fish bone migration: complications, diagnostic challenges, and treatment strategies 鱼骨迁移:并发症,诊断挑战和治疗策略
IF 8 1区 医学 Q1 EMERGENCY MEDICINE Pub Date : 2025-04-23 DOI: 10.1186/s13017-025-00611-9
Deng Li, Wanting Zeng, Jichuan Chen
Fish bone impaction in the pharynx is a common otolaryngological emergency. However, if the fish bone perforates the pharyngeal wall or the gastrointestinal wall and migrates to the neck tissues or organs, entering the lungs, mediastinum, heart, liver, biliary tract, spleen, pancreas, or other structures, or damages major blood vessels in the thoracic or abdominal cavities, it can lead to severe complications. This condition is rare and dangerous, potentially resulting in a series of serious complications, including neck abscess, thyroid abscess, thrombosis or air embolism of the cervical vessels, esophageal perforation, rupture of major mediastinal vessels, mediastinitis, aorto-esophageal fistula, lung abscess, spinal injury, sepsis, splenic abscess, hepatic abscess, anal fistula, and it may even be misdiagnosed as a tumor. This narrative review synthesizes evidence on fish bone translocation complications to (1) identify high-risk clinical presentations, (2) guide site-specific imaging selection, and (3) inform multidisciplinary management strategies. Use the keyword “fishbone” to systematically search articles from PubMed、CNKI and Embase databases from 1972 to 2024. Review all original articles and include them in this review where appropriate. This narrative review synthesizes evidence from case reports and observational studies to explore complications and management of fish bone translocation in uncommon sites. Given the predominance of heterogeneous case reports, a formal systematic review with meta-analysis was not feasible; however, we employed systematic search strategies to minimize selection bias. To avoid severe complications, it is crucial to provide comprehensive information on the management of fish bone impaction. When fish bone removal cannot be achieved using laryngoscopy, prompt and decisive surgical intervention is required to extract the foreign body.
鱼骨嵌塞在咽是一种常见的耳鼻喉急症。但是,如果鱼骨穿过咽壁或胃肠壁,迁移到颈部组织或器官,进入肺、纵隔、心脏、肝脏、胆道、脾脏、胰腺等结构,或损害胸腔、腹腔的主要血管,则可导致严重的并发症。该病罕见且危险,可导致颈部脓肿、甲状腺脓肿、颈血管血栓形成或空气栓塞、食管穿孔、纵隔大血管破裂、纵隔炎、主动脉-食管瘘、肺脓肿、脊髓损伤、败血症、脾脓肿、肝脓肿、肛瘘等一系列严重并发症,甚至可能误诊为肿瘤。本文综合了有关鱼骨易位并发症的证据,以(1)确定高危临床表现,(2)指导特定部位的影像学选择,(3)为多学科管理策略提供信息。使用关键词“鱼骨”系统检索1972年至2024年PubMed、CNKI和Embase数据库中的文章。审查所有的原始文章,并在适当的地方将它们包括在本审查中。本文综合了来自病例报告和观察性研究的证据,以探讨罕见部位鱼骨移位的并发症和处理。鉴于异质性病例报告占主导地位,采用meta分析的正式系统评价是不可行的;然而,我们采用了系统的搜索策略来最小化选择偏差。为了避免严重的并发症,提供有关治疗鱼骨嵌塞的综合信息至关重要。当喉镜检查无法去除鱼骨时,需要及时果断的手术干预以取出异物。
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引用次数: 0
Hemothorax due to inferior phrenic artery injury from blunt trauma: a case series and systematic review 钝性创伤致膈下动脉损伤致血胸:一个病例系列和系统回顾
IF 8 1区 医学 Q1 EMERGENCY MEDICINE Pub Date : 2025-04-19 DOI: 10.1186/s13017-025-00609-3
Akira Kuriyama, Yumi Kato, Ryosuke Echigoya
Hemothorax is a common complication of thoracic trauma, often associated with morbidity and mortality. While intercostal and internal mammary arteries are commonly involved, the inferior phrenic artery (IPA) is rarely the source of hemothorax following blunt trauma. We aimed to investigate the prevalence of IPA-related hemothorax by describing a single-center case series and to outline the characteristics and management of hemothorax secondary to IPA injury with a systematic review. We conducted a chart review of patients with trauma to identify patients with hemothorax due to IPA injury at a Japanese tertiary care hospital between 2013 and 2019. We performed a systematic review of published studies about this condition by searching PubMed, EMBASE, and ICHUSHI from their inception to January 18, 2025, summarizing their clinical characteristics, treatment, and prognosis. Among 231 patients with hemothorax following blunt trauma, 3 (1.3%) were caused by IPA injury. The systematic review identified published articles for 16 additional reports, yielding 19 reports for analysis. IPA injury was typically diagnosed after 1 day to 3 weeks post-injury, with 94% of patients presenting with shock. Transcatheter arterial embolization (TAE) was the primary treatment, although many patients required additional interventions such as thoracotomy and hematoma evacuation. Complications included pneumonia, and the mortality rate was 11%. Hemothorax due to IPA injury following blunt trauma may be rare and potentially life-threatening. While endovascular techniques such as TAE were effective in many cases, repeated bleeding and substantial hematoma necessitated repeat interventions or surgical procedures. Despite an overall favorable prognosis, significant risks for complications and mortality remained. Thus, early recognition and increased awareness of IPA injury in patients with trauma are essential for improving outcomes.
血胸是胸外伤的常见并发症,常伴有发病率和死亡率。虽然通常累及肋间动脉和乳腺内动脉,但钝性创伤后血胸的来源很少是膈下动脉。我们的目的是通过描述单中心病例系列来调查IPA相关血胸的患病率,并通过系统回顾概述IPA损伤继发血胸的特征和处理。我们对2013年至2019年日本一家三级保健医院的创伤患者进行了图表回顾,以确定因IPA损伤导致的血胸患者。我们通过检索PubMed、EMBASE和ICHUSHI,从研究开始到2025年1月18日,对已发表的关于该疾病的研究进行了系统回顾,总结了它们的临床特征、治疗和预后。231例钝性外伤后血胸患者中,3例(1.3%)为IPA损伤所致。系统审查为另外16份报告确定了已发表的文章,产生19份报告供分析。IPA损伤通常在损伤后1天至3周被诊断出来,94%的患者表现为休克。经导管动脉栓塞(TAE)是主要的治疗方法,尽管许多患者需要额外的干预措施,如开胸和血肿清除。并发症包括肺炎,死亡率为11%。钝性外伤后因IPA损伤引起的血胸可能是罕见的,并且可能危及生命。虽然血管内技术如TAE在许多情况下是有效的,但反复出血和大量血肿需要重复干预或外科手术。尽管总体预后良好,但并发症和死亡率的显著风险仍然存在。因此,创伤患者早期识别和提高对IPA损伤的认识对于改善预后至关重要。
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引用次数: 0
A China-Based exploration of surgical timing for polytrauma with a focus on fracture reconstruction 以骨折重建为重点的多发伤手术时机的中国探索
IF 8 1区 医学 Q1 EMERGENCY MEDICINE Pub Date : 2025-04-16 DOI: 10.1186/s13017-025-00607-5
Chenning Ding, Mingwang Jia, Xing Han, Jiahui Zhang, Xin Zhao, Xiguang Sang
For patients with severe polytrauma and fractures, early fracture reconstruction surgery under stable conditions can significantly reduce pulmonary and other complications. However, premature surgical intervention may heighten infection risk, adversely affecting the patient’s prognosis. Consequently, determining the optimal timing of surgery is crucial for patients with multiple traumatic injuries. Given China’s healthcare context, this study will assess injury severity and perform definitive fracture reconstruction at specified post-trauma intervals. Postoperative infection rates, including wound infections, other complication incidences, hospital stay duration, treatment costs, and long-term outcomes will be observed and compared to identify the optimal timing for surgical intervention. This study also aims to develop effective polytrauma management models. By applying accessible criteria and choosing suitable timing for fracture reconstruction, we can better assess patient conditions, reduce complications, and minimize the surgery’s “second hit” effect, addressing an important research gap regarding optimal surgical timing for polytrauma in China. This study collected data on 200 patients treated at our hospital between March 2023 and March 2024, with an average age of 47.24 ± 16.56 years and an average Injury Severity Score (ISS) of 25.85 ± 13.35. A total of 250 fractures received definitive fixation in the initial surgery, including femoral fractures (n = 75), spinal fractures (n = 46), pelvic ring fractures (n = 49), tibial fractures (n = 25), acetabular fractures (n = 12), humeral fractures (n = 12), and other fractures (n = 5) (including clavicle, radius and ulna, calcaneus, and patella). Among these patients, 151 underwent single-fracture reconstruction, 42 had two fractures reconstructed, and 5 had three fractures treated during the first surgery. The study protocol excluded patients with absolute contraindications, including bacteremia and infections near the surgical site. Additional inclusion criteria required stable vital signs (temperature < 38.5 °C with a downward trend, systolic blood pressure > 100 mmHg, stable traumatic brain injury status) and blood routine (white blood cell count < 22.0 × 10⁹/L with a neutrophil percentage < 90%, both trending downward; platelet count > 50 × 10⁹/L; hemoglobin > 90 g/L). Based on these criteria, historical cohorts were identified and assigned to either an experimental group or a control group. Observed outcomes included postoperative complications, wound healing grades, inflammatory markers, changes in vital signs, length of hospital stay, costs, and long-term follow-up results. Among the patients, 97 underwent surgery after meeting the specified criteria for fracture reconstruction, while 103 received surgery without meeting these criteria. Patients who met the surgical criteria demonstrated superior outcomes, with lower complication rates (including pneumonia and respiratory distress syndrom
对于严重多发伤及骨折患者,在病情稳定的情况下早期进行骨折重建手术,可显著减少肺部及其他并发症。然而,过早的手术干预可能会增加感染风险,对患者的预后产生不利影响。因此,确定手术的最佳时机是至关重要的患者多创伤性损伤。考虑到中国的医疗环境,本研究将评估损伤的严重程度,并在特定的创伤后间隔进行明确的骨折重建。术后感染率,包括伤口感染、其他并发症发生率、住院时间、治疗费用和长期结果将被观察和比较,以确定手术干预的最佳时机。本研究也旨在建立有效的多重创伤管理模式。通过应用可获得的标准和选择合适的骨折重建时机,我们可以更好地评估患者的病情,减少并发症,并最大限度地减少手术的“二次打击”效应,解决中国在多伤最佳手术时机方面的重要研究空白。本研究收集了2023年3月至2024年3月在我院就诊的200例患者的资料,平均年龄为47.24±16.56岁,平均损伤严重程度评分(ISS)为25.85±13.35。在初始手术中,共有250例骨折接受了最终固定,包括股骨骨折(n = 75)、脊柱骨折(n = 46)、骨盆环骨折(n = 49)、胫骨骨折(n = 25)、髋臼骨折(n = 12)、肱骨骨折(n = 12)和其他骨折(n = 5)(包括锁骨、桡骨、尺骨、跟骨和髌骨)。其中单骨折重建151例,双骨折重建42例,三骨折首次手术5例。研究方案排除了绝对禁忌症的患者,包括菌血症和手术部位附近的感染。其他纳入标准需要稳定的生命体征(体温100 mmHg,创伤性脑损伤状态稳定)和血常规(白细胞计数50 × 10⁹/L;血红蛋白> 90 g/L)。根据这些标准,确定历史队列并将其分配到实验组或对照组。观察结果包括术后并发症、伤口愈合等级、炎症标志物、生命体征变化、住院时间、费用和长期随访结果。其中97例患者符合规定的骨折重建标准后接受了手术,103例患者不符合规定的骨折重建标准而接受了手术。符合手术标准的患者表现出较好的结果,并发症发生率较低(包括肺炎和呼吸窘迫综合征),手术切口愈合较好,术后意识恢复较快,总住院时间和ICU住院时间较短,住院费用较低,9个月随访时关节活动度较高,生活质量评估高于不符合标准的患者。在符合标准的患者中,脊柱骨折患者的生活质量更好,股骨骨折患者的骨折愈合更好。对于多发创伤骨折患者,一旦满足手术要求就进行手术,术后早期肺部并发症少,意识恢复快,伤口感染率低,住院和ICU时间短,费用降低,术后预后改善。该方案对于大多数需要固定的多发创伤患者是安全有效的,特别是那些机械不稳定的股骨、骨盆、髋臼或脊柱骨折患者。
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引用次数: 0
A systematic review of the predictive factors for the recurrence of acute pancreatitis 急性胰腺炎复发预测因素的系统综述
IF 8 1区 医学 Q1 EMERGENCY MEDICINE Pub Date : 2025-04-12 DOI: 10.1186/s13017-025-00601-x
Daniela Pacella, Adriano De Simone, Adolfo Pisanu, Gianluca Pellino, Lucio Selvaggi, Valentina Murzi, Eleonora Locci, Giulia Ciabatti, Laura Mastrangelo, Elio Jovine, Matteo Rottoli, Giacomo Calini, Stefano Cardelli, Fausto Catena, Carlo Vallicelli, Raffaele Bova, Gabriele Vigutto, Fabrizio D’Acapito, Giorgio Ercolani, Leonardo Solaini, Alan Biloslavo, Paola Germani, Camilla Colutta, Pasquale Lepiane, Rosa Scaramuzzo, Savino Occhionorelli, Domenico Lacavalla, Maria Grazia Sibilla, Stefano Olmi, Matteo Uccelli, Alberto Oldani, Alessio Giordano, Tommaso Guagni, Davina Perini, Francesco Pata, Bruno Nardo, Daniele Paglione, Giusi Franco, Matteo Donadon, Marcello Di Martino, Salomone Di Saverio, Luca Cardinali, Grazia Travaglini, Dario Bruzzese, Mauro Podda
Acute Pancreatitis (AP) is a prevalent clinical pancreatic disorder characterized by acute inflammation of the pancreas, frequently associated with biliary or alcoholic events. If not treated with cholecystectomy after the first episode, patients may experience a recurrence of AP, with consequent need for emergency surgery and increased risk of death. Analyzing the risk factors that may contribute to the recurrence of Biliary and Alcoholic Pancreatitis (BAP and AAP), future research can be driven toward new solutions for preventing and treating this pancreatic disease. A systematic review was conducted selecting studies from BiomedCentral, PubMed, Scopus and Web of Science by two independent reviewers. Publications were considered only if written in English in the time interval between January 2000 and June 2024 and investigated the risk factors for the recurrence of BAP and AAP. At the end of the selection, a quality assessment phase was conducted using the PROBAST tool. In this systematic review, 8 articles were selected out of 6.945, involving a total sample of 11.271 patients of which 38.77% developed recurrence episodes. 37.5% of the included studies focus on recurrent acute biliary pancreatitis (RBAP), while 62.5% are dedicated to recurrent acute alcoholic pancreatitis (RAAP). The risk factors for the recurrence of AP showed a clear differentiation between the alcoholic and biliary etiology. Most of the considered studies adopted a retrospective design, characterized by a susceptibility to potential methodological biases. However, the trend indicated a more recent increase in prospective studies, together with a greater focus on identifying and understanding the possible risk factors associated with the recurrence of acute pancreatitis (RAP). This result highlighted the progress in the scientific approach toward a more rigorous and systematic assessment of the causes and dynamics that influence the recurrence of the disease. Studies highlighted the importance of lifestyle factors, clinical complications, and surgical interventions that can impact the risk of biliary or alcoholic recurrent acute pancreatitis. Increased and systematic adoption of artificial intelligence-based tools could significantly impact future knowledge relating to the risks of recurrence and relative possibilities of prevention.
急性胰腺炎(AP)是一种常见的临床胰腺疾病,以胰腺急性炎症为特征,常伴有胆道或酒精事件。如果在首次发作后不进行胆囊切除术,患者可能会经历AP复发,因此需要紧急手术,并增加死亡风险。分析可能导致胆汁性和酒精性胰腺炎(BAP和AAP)复发的危险因素,可以推动未来的研究为预防和治疗这种胰腺疾病提供新的解决方案。由两名独立审稿人对来自BiomedCentral、PubMed、Scopus和Web of Science的研究进行系统评价。仅考虑2000年1月至2024年6月期间以英文撰写的出版物,并调查BAP和AAP复发的危险因素。在选择结束时,使用PROBAST工具进行质量评估阶段。本系统综述从6.945篇文献中筛选出8篇,共涉及11.271例患者,其中38.77%的患者复发。37.5%的纳入研究集中于复发性急性胆源性胰腺炎(RBAP),而62.5%的研究集中于复发性急性酒精性胰腺炎(RAAP)。AP复发的危险因素显示酒精性和胆道性病因有明显的区别。大多数考虑的研究采用回顾性设计,其特点是对潜在的方法学偏差敏感。然而,这一趋势表明,最近前瞻性研究的增加,以及对识别和理解与急性胰腺炎(RAP)复发相关的可能危险因素的更多关注。这一结果突出了科学方法的进展,以更严格和系统地评估影响疾病复发的原因和动态。研究强调了生活方式因素、临床并发症和手术干预的重要性,这些因素可以影响胆道性或酒精性复发性急性胰腺炎的风险。更多和系统地采用基于人工智能的工具可能会显著影响与复发风险和相对预防可能性相关的未来知识。
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World Journal of Emergency Surgery
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