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COVID-19 mRNA-Vaccines During Pregnancy are Safe Based on Postpartum Placental Immune Profiles in Both Maternal and Fetal Compartments. 基于产妇和胎儿室产后胎盘免疫谱,妊娠期间接种COVID-19 mrna疫苗是安全的
IF 1.7 3区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-12-23 DOI: 10.1097/PTS.0000000000001304
Lotte E van der Meeren, Michelle Broekhuizen, Thierry T P van den Bosch, Disha Vadgama, Dana A M Mustafa, Irwin K M Reiss, Pieter L A Fraaij, Sam Schoenmakers
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引用次数: 0
Relations Between Suicide Risk and Patient Safety Attitudes Among the Nursing Team in a Brazilian Context. 巴西护理团队中自杀风险与患者安全态度之间的关系。
IF 1.7 3区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-12-23 DOI: 10.1097/PTS.0000000000001305
Kariciele Cristina Corrêa, Lúcio Borges de Araújo, Helenitta Melo da Silva Alves, Liz Marina Corrêa Ferreira, Frank José Silveira Miranda, Marcelle Aparecida de Barros Junqueira

Objectives: To analyze the aspects of suicide risks and their relation to patient safety attitudes among the nursing staff of a large public university hospital in Brazil.

Methods: A cross-sectional and descriptive study with 226 nursing workers from a large public university hospital in Brazil. Socioprofessional information, health conditions, and family history related to suicide risk were collected through the Mini International Neuropsychiatric Interview Plus and the Safety Attitudes Questionnaire. A 95% CI was considered, and statistical tests such as the Student t test, χ2, analysis of variance, and multiple linear regression were used.

Results: Most of the safety attitudes were below the average score considered positive (mean Safety Attitudes Questionnaire value >0.75), and 41 (18.1%) workers were considered to have any degree of suicide risk. Participants with parents or siblings who had attempted suicide were 3.44 times more likely to have moderate or high suicide risk. Negative safety attitudes were associated with health conditions and family history, considered suicide risk factors. Participants with moderate or high suicide risk were 2.83 times more likely to have worse patient safety attitudes concerning job satisfaction.

Conclusions: This study reveals significant associations between patient safety attitudes and the mental health of nursing workers, expanding the view of worker health management actions and, consequently, patient safety culture.

目的:分析巴西某大型公立大学医院护理人员自杀风险的各方面及其与患者安全态度的关系。方法:对巴西某大型公立大学医院226名护理人员进行横断面和描述性研究。通过迷你国际神经精神病学访谈Plus和安全态度问卷收集与自杀风险相关的社会专业信息、健康状况和家族史。采用95% CI,采用学生t检验、χ2、方差分析和多元线性回归等统计检验。结果:大多数工人的安全态度低于被认为是积极的平均得分(安全态度问卷平均值>0.75),41名工人(18.1%)被认为有不同程度的自杀风险。父母或兄弟姐妹曾试图自杀的参与者有中度或高度自杀风险的可能性高出3.44倍。消极的安全态度与健康状况和家族史有关,被认为是自杀风险因素。中度或高度自杀风险的参与者对工作满意度的患者安全态度较差的可能性是其2.83倍。结论:本研究揭示了患者安全态度与护理人员心理健康之间的显著关联,扩展了护理人员健康管理行为的观点,从而扩展了患者安全文化的观点。
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引用次数: 0
The Implementation of Perioperative Geriatric Management Could Decrease the Incidence of Postoperative Delirium in the Elderly Undergoing Major Orthopedic Surgeries. 实施围手术期老年管理可降低老年骨科大手术患者术后谵妄的发生率。
IF 1.7 3区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-12-23 DOI: 10.1097/PTS.0000000000001307
Yan Zou, Tingzhi Deng, Yu Xu, Qing Zheng, Yuan Wu, Shan Hui, Cuizhong Liu, An Wei

Objectives: This study aimed to explore the association of perioperative geriatric management (PGM) in major orthopedic surgeries.

Methods: One hundred seventy-five participants aged 75 and older were in-hospital patients who underwent major orthopedic surgery from September 2020 to September 2021, and they received PGM and necessary treatment for indicators with abnormal value (the PGM group). Another 175 participants in the control group only received the evaluation part of the PGM, recruited by filtering in the electronic medical record system from March 2016 to March 2017. The treatment included joint intervention of psychiatrists and rehabilitation physicians. For example, for patients at risk for falling, evaluation of inadequate blood volume, delirium, abnormal gait, and visual impairment should be performed. The logistic regression analysis was adopted to determine the association of PGM and postoperative delirium.

Results: The prevalence of postoperative delirium among participants was 13.71%. Compared with the empirical treatment group, the postoperative delirium was significantly decreased (7.43% versus 14.29%) (P<0.05). Compared with the control group, participants were in the PGM group were at lower risk of postoperative delirium, mainly attributed to these following factors: Charlson comorbidity index <5 [odds ratio (OR)=0.620; 95% CI: 0.010-0.623], mini cog >2 (OR=0.224; 95% CI: 0.061-0.824), Confusion Assessment Method score indicating low risk (OR=0.079; 95% CI: 0.010-0.623), nutritional risk screening scale <3 (OR=0.306; 95% CI: 0.095-0.989), and major adverse cardiovascular events <3 (OR=0.253; 95% CI: 0.073-0.720). After adjusting for the length of hospital stay and reason for hospitalization, the association between the parameters above and postoperative delirium is still significant (P<0.05).

Conclusions: The implementation of the PGM could decrease the incidence of postoperative delirium significantly, which might contribute to improving the overall prognosis in elderly patients who underwent major orthopedic surgeries.

目的:本研究旨在探讨围手术期老年管理(PGM)与骨科大手术的关系。方法:研究对象为2020年9月至2021年9月住院接受骨科大手术的175例75岁及以上患者,均接受PGM及指标异常值的必要治疗(PGM组)。另175名对照组参与者仅接受PGM的评估部分,于2016年3月至2017年3月在电子病历系统中通过筛选招募。治疗包括精神科医生和康复医生的联合干预。例如,对于有跌倒风险的患者,应评估血容量不足、谵妄、步态异常和视力障碍。采用logistic回归分析确定PGM与术后谵妄的关系。结果:术后谵妄发生率为13.71%。与经验治疗组比较,术后谵妄明显减少(7.43%比14.29%)(P2 (OR=0.224;95% CI: 0.061-0.824),混淆评估方法评分提示低风险(OR=0.079;结论:PGM的实施可显著降低老年骨科大手术患者术后谵妄的发生率,有助于改善老年骨科大手术患者的整体预后。
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引用次数: 0
Assessing Between- and Within-Hospital Differences in Patient Safety Between Medicaid and Privately Insured Hospital Patients. 评估医疗补助和私人保险医院患者在医院之间和医院内部的患者安全差异。
IF 1.7 3区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-12-01 Epub Date: 2024-08-28 DOI: 10.1097/PTS.0000000000001270
Anuj Gangopadhyaya

Objectives: The aims of the study are to investigate differences in rates of adverse safety events between nonelderly adult patients with Medicaid and those with private insurance and to assess whether differences are driven by differences in access to quality hospitals or differences in the quality of care delivered within hospitals.

Data source: Inpatient records from 26 states in 2017 were collected from the Agency for Health Care Research and Quality's Hospital Cost and Utilization Project.

Study design: This study measures differences in 11 patient safety indicators between patients with Medicaid coverage and patients with private insurance coverage. I use regression analysis to investigate differences in adverse safety events within hospitals. I further establish hospital-level quality based on overall rates of adverse safety events and use regression analysis to evaluate the difference in the probability of admission to high-quality hospitals.

Data collection/extraction: This study uses hospital discharge data that is restricted to adults ages 19-64 with Medicaid or private coverage.

Principal findings: Relative to privately insured patients, Medicaid patients had significantly higher rates of adverse safety events on 8 of 11 patient safety indicators, including on 6 of 7 surgery-related patient safety indicators. Medicaid patients experience respiratory failure and sepsis infections at rates that are 2.9 and 2.5 cases per 1000 greater than rates experienced by privately insured patients. After adjusting for demographic characteristics, patient diagnostic classifications and comorbidities, and geographic factors, 6 of 11 differences in patient safety indicators remained large and statistically significant. These differences were unchanged when further including hospital indicators, indicating that Medicaid and privately insured patients receive different quality of care within hospitals. There is little association between overall hospital quality and differences in the probability of admission between Medicaid and privately covered patients.

Conclusions: Medicaid patients received lower quality of care, based on patient safety metrics, relative to privately insured patients within the same hospitals. Reducing payer disparities in adverse safety events requires reforming staffing and treatment patterns for Medicaid and privately insured patients within hospitals.

Study date and location: Analysis for this study was conducted in 2023 at the Urban Institute and at Loyola University Chicago.

研究目的该研究的目的是调查享受医疗补助的非老年成年患者与享受私人保险的非老年成年患者之间在不良安全事件发生率方面的差异,并评估这种差异是否是由优质医院就诊机会的差异或医院内提供的护理质量的差异造成的:研究设计:本研究测量了医疗补助覆盖患者与私人保险覆盖患者在 11 项患者安全指标上的差异。我采用回归分析法调查医院内部不良安全事件的差异。根据不良安全事件的总体发生率,我进一步确定了医院层面的质量,并利用回归分析评估了入住高质量医院的概率差异:本研究使用的医院出院数据仅限于 19-64 岁、享受医疗补助或私人保险的成年人:与私人保险患者相比,在11项患者安全指标中的8项指标上,医疗补助患者的不良安全事件发生率明显高于私人保险患者,其中包括7项手术相关患者安全指标中的6项。医疗补助患者的呼吸衰竭和败血症感染率分别比私人保险患者高出 2.9 和 2.5 例/1000。在对人口统计学特征、患者诊断分类和合并症以及地理因素进行调整后,11 项患者安全指标中仍有 6 项差异较大,且具有统计学意义。在进一步纳入医院指标后,这些差异保持不变,表明医疗补助和私人保险患者在医院内接受的护理质量不同。医院整体质量与医疗补助和私人保险患者的入院概率差异之间几乎没有关联:结论:根据患者安全指标,在同一家医院中,医疗补助患者接受的护理质量低于私人保险患者。要减少支付方在不良安全事件方面的差异,就必须改革医院内针对医疗补助和私人保险患者的人员配备和治疗模式:本研究的分析工作于 2023 年在城市研究所和芝加哥洛约拉大学进行。
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引用次数: 0
Adverse Events in Patients Transitioning From the Emergency Department to the Inpatient Setting. 从急诊科转入住院治疗的患者的不良事件。
IF 1.7 3区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-12-01 Epub Date: 2024-09-27 DOI: 10.1097/PTS.0000000000001284
Dennis Tsilimingras, Jeffrey Schnipper, Liying Zhang, Phillip Levy, Steven Korzeniewski, James Paxton

Objectives: The objective of this study was to determine the incidence and types of adverse events (AEs), including preventable and ameliorable AEs, in patients transitioning from the emergency department (ED) to the inpatient setting. A second objective was to examine the risk factors for patients with AEs.

Methods: This was a prospective cohort study of patients at risk for AEs in 2 urban academic hospitals from August 2020 to January 2022. Eighty-one eligible patients who were being admitted to any internal medicine or hospitalist service were recruited from the ED of these hospitals by a trained nurse. The nurse conducted a structured interview during admission and referred possible AEs for adjudication. Two blinded trained physicians using a previously established methodology adjudicated AEs.

Results: Over 22% of 81 patients experienced AEs from the ED to the inpatient setting. The most common AEs were adverse drug events (42%), followed by management (38%), and diagnostic errors (21%). Of these AEs, 75% were considered preventable. Patients who stayed in the ED longer were more likely to experience an AE (adjusted odds ratio = 1.99, 95% confidence interval = 1.19-3.32, P = 0.01).

Conclusions: AEs were common for patients transitioning from the ED to the inpatient setting. Further research is needed to understand the underlying causes of AEs that occur when patients transition from the ED to the inpatient setting. Understanding the contribution of factors such as length of stay in the ED will significantly help efforts to develop targeted interventions to improve this crucial transition of care.

研究目的本研究旨在确定从急诊科(ED)转入住院治疗的患者中不良事件(AE)的发生率和类型,包括可预防和可改善的不良事件。第二个目标是研究发生不良事件患者的风险因素:这是一项前瞻性队列研究,研究对象是 2020 年 8 月至 2022 年 1 月期间在两家城市学术医院就诊的有 AE 风险的患者。一名经过培训的护士从这两家医院的急诊室招募了81名符合条件的内科或住院医师服务住院患者。护士在患者入院时对其进行结构化访谈,并将可能发生的 AE 移交给医生进行判定。两名经过盲法培训的医生采用之前确定的方法对AE进行判定:结果:81 名患者中有 22% 以上从急诊室到住院期间都出现了 AE。最常见的不良事件是药物不良事件(42%),其次是管理不良事件(38%)和诊断错误(21%)。在这些不良事件中,75%被认为是可以预防的。在急诊室停留时间较长的患者更有可能发生 AE(调整后的几率比 = 1.99,95% 置信区间 = 1.19-3.32,P = 0.01):从急诊室转入住院环境的患者发生 AE 的情况很常见。需要进一步开展研究,以了解患者从急诊室转入住院环境时发生 AEs 的根本原因。了解急诊室住院时间等因素的影响将大大有助于制定有针对性的干预措施,改善这一关键的护理过渡。
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引用次数: 0
From Compliance to Collaboration: Learning From Transatlantic Frameworks for Healthcare Safety Improvement. 从遵守到合作:从跨大西洋医疗安全改进框架中学习。
IF 1.7 3区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-12-01 Epub Date: 2024-08-07 DOI: 10.1097/PTS.0000000000001257
Olivia Lounsbury, Mark Sujan, Ken Catchpole
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引用次数: 0
Involving Patients and/or Their Next of Kin in Serious Adverse Event Investigations: A Qualitative Study on Hospital Perspectives. 让患者和/或其近亲参与严重不良事件调查:关于医院观点的定性研究。
IF 1.7 3区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-12-01 Epub Date: 2024-10-16 DOI: 10.1097/PTS.0000000000001282
Linda J Knap, Rachel I Dijkstra-Eijkemans, Roland D Friele, Johan Legemaate

Background: The involvement of patients or next of kin (P/N) after a serious adverse event (SAE) is evolving. Beyond providing mandatory information, there is growing recognition of the need to incorporate their interests. This study explores practical manifestations of P/N involvement and identifies significant considerations for hospitals.

Methods: The data collection involved various qualitative research methods: 7 focus groups with 56 professionals from 37 hospitals, an interview with 2 representatives from the Dutch Association of Hospitals, and an interactive reflection seminar with over 60 participants from 34 hospitals. Before the focus groups, a brief questionnaire was sent out to survey participants' practices regarding into SAE investigations. After the study, another questionnaire was distributed to gather suggestions for future improvements and to identify their lessons learned. Thematic analysis was applied to the gathered data to identify key themes.

Results: Hospitals are increasingly acknowledging the interests and perspectives of P/N, recognizing their potential contributions to organizational learning and improvement. P/N involvement following SAEs includes active participation in different stages of the investigation process, not just passive information dissemination. Important factors influencing involvement are the provision of (emotional) support, identification of needs, and transparency of the SAE investigation.

Conclusions: This study enhances understanding of evolving practices surrounding P/N involvement in the context of SAEs in Dutch hospitals. The findings highlight the importance of promoting meaningful involvement, recognizing the significance of P/N experiences, and fostering a culture of transparency and collaboration. By examining the dynamics of involvement, this research aims to inform policy development and facilitate the implementation of patient-centered approaches to post-SAE care.

背景:严重不良事件(SAE)发生后,患者或近亲属(P/N)的参与正在不断发展。除了提供强制性信息外,越来越多的人认识到有必要纳入他们的利益。本研究探讨了 P/N 参与的实际表现形式,并确定了医院的重要考虑因素:数据收集采用了多种定性研究方法:与来自 37 家医院的 56 名专业人员进行了 7 次焦点小组讨论,与荷兰医院协会的 2 名代表进行了一次访谈,与来自 34 家医院的 60 多名参与者进行了一次互动反思研讨会。在焦点小组讨论之前,我们向参与者发放了一份简短的调查问卷,调查他们在 SAE 调查方面的做法。研究结束后,还发放了另一份调查问卷,以收集未来改进建议并总结经验教训。对收集到的数据进行了主题分析,以确定关键主题:医院越来越重视 P/N 的利益和观点,认识到他们对组织学习和改进的潜在贡献。发生 SAE 后,P/N 的参与包括积极参与调查过程的不同阶段,而不仅仅是被动地传播信息。影响参与的重要因素包括提供(情感)支持、确定需求以及 SAE 调查的透明度:本研究加深了人们对荷兰医院在发生 SAE 时,P/N 参与相关实践的理解。研究结果强调了促进有意义的参与、承认 P/N 经历的重要性以及培养透明与合作文化的重要性。通过研究参与的动态变化,本研究旨在为政策制定提供信息,并促进以患者为中心的SAE后护理方法的实施。
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引用次数: 0
The Predictors of Patient Safety Culture in Hospital Setting: A Systematic Review. 医院环境中患者安全文化的预测因素:系统回顾
IF 1.7 3区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-12-01 Epub Date: 2024-10-22 DOI: 10.1097/PTS.0000000000001285
Anja Vibe, Sara Haurum Rasmussen, Nikolaj Ohm Pranger Rasmussen, Doris Østergaard, Peter Dieckmann

Introduction: Patient safety (PS) is a global public health concern. It is estimated that 10% of patients experience preventable harm while hospitalized. Patient safety culture (PSC) has been recognized as essential to improving PS, drawing inspiration from other high-risk industries. In PS research, however, PSC poses conceptual challenges, with inconsistent terminology, a lack of definitions, and limited use of substantiating theory. Despite these challenges, PSC remains widely used in PS research and practice, as it is seen as a potential gateway to understanding sociotechnical complex aspects of the healthcare system and improving safe patient treatment and care.

Objectives: This review explores the concept of PSC in a hospital setting. How PSC is used as an outcome, thus exploring the theoretical position underpinning PSC, which predictors impact PSC, and how these predictors are related to PSC.

Method: Using a search of 3 electronic databases, 23 studies that met the inclusion criteria were selected for review.

Results: The review identified 81 predictors of PSC. Study population, unit of analysis and method varied widely. PSC as an outcome was assessed based on one of 4 surveys. Thus, the underpinning position of the PSC construct is dominated by an organizational/managerial approach.

Conclusions: The large number of predictors explored and the range in outcome measures, units of analysis, and methods make it hard to establish any causal relationship. We argue that studies closer to actual practices in the messy conditions of clinical practice are needed.

引言患者安全(Patient Safety,PS)是一个全球性的公共卫生问题。据估计,10% 的患者在住院期间遭受了可预防的伤害。从其他高风险行业中汲取灵感,患者安全文化(PSC)已被认为是改善患者安全的关键。然而,在患者安全研究中,患者安全文化带来了概念上的挑战,如术语不一致、缺乏定义、证实理论的使用有限等。尽管存在这些挑战,PSC 仍被广泛应用于 PS 研究和实践中,因为它被视为理解医疗保健系统复杂的社会技术方面以及改善患者安全治疗和护理的潜在途径:本综述探讨了医院环境中的 PSC 概念。如何将 PSC 作为一种结果,从而探讨 PSC 的理论基础、哪些预测因素会影响 PSC 以及这些预测因素与 PSC 的关系:方法:通过对 3 个电子数据库的检索,选择了 23 项符合纳入标准的研究进行综述:结果:综述确定了 81 项预测 PSC 的因素。研究人群、分析单位和方法差异很大。作为结果的 PSC 是根据 4 项调查中的一项进行评估的。因此,组织/管理方法主导了 PSC 构建的基础地位:结论:所探讨的预测因素数量众多,结果测量、分析单位和方法各不相同,因此很难确定任何因果关系。我们认为,需要在混乱的临床实践条件下进行更贴近实际做法的研究。
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引用次数: 0
Exploring the Relationship Between Hospital Patient Safety Culture and Performance on Measures of Hospital-Acquired Conditions. 探究医院患者安全文化与医院获得性病症指标表现之间的关系。
IF 1.7 3区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-12-01 DOI: 10.1097/PTS.0000000000001281
Pejmon Noghrehchi, Jennifer L Hefner, Hendrik Stegall, Daniel M Walker

Objective: The aim of the study is to examine the relationship between hospital perceptions of patient safety culture and the incidence of hospital-acquired conditions (HACs) included in Medicare's HAC Reduction Program utilizing updated and standardized metrics.

Methods: The pooled cross-sectional study design utilized the 2018 and 2021 datasets from (1) the Agency for Healthcare Research and Quality's Hospital Survey on Patient Safety Culture (HSOPS), (2) the American Hospital Association's annual survey, and (3) the Center for Medicare and Medicaid's Hospital Compare dataset. The final analytic sample included 131 acute care, nonfederal, U.S. facilities. Multivariable linear regression models were used to compare the HSOPS domains of patient safety culture to CMS's HAC metrics.

Results: Controlling for hospital structural and patient-mix characteristics, hospitals with higher staff-reported ratings of overall patient safety culture ('overall perceptions of patient safety' and 'patient safety grade') had significantly lower rates of HACs, including total HAC rate, catheter-associated urinary tract infections, and central line-associated blood stream infections (P's < 0.000-0.044). Higher HSOPS domain scores were variably associated with lower HAC rates, with consistently significant associations found for domains related to nonpunitive, open communication (P's < 0.05).

Conclusions: Our relatively robust results suggest that while patient safety culture may not be the only strategy necessary to improve HAC rates, it needs to be aligned with other efforts to improve quality and safety. This underscores the importance of cultivating a culture of psychological safety that promotes open feedback and communication about errors.

研究目的本研究旨在利用最新的标准化指标,研究医院对患者安全文化的认知与医疗保险HAC减少计划中的医院获得性病症(HAC)发生率之间的关系:汇总横断面研究设计利用了 2018 年和 2021 年的数据集,这些数据集来自:(1)医疗保健研究与质量局的医院患者安全文化调查(HSOPS);(2)美国医院协会的年度调查;(3)医疗保险和医疗补助中心的医院比较数据集。最终的分析样本包括 131 家美国非联邦急症护理机构。多变量线性回归模型用于比较 HSOPS 患者安全文化领域与 CMS 的 HAC 指标:在控制医院结构和患者组合特征的前提下,员工报告的患者安全文化总体评分("患者安全总体感知 "和 "患者安全等级")越高的医院,其HAC率(包括总HAC率、导管相关性尿路感染和中心管线相关性血流感染)明显越低(P's < 0.000-0.044)。较高的 HSOPS 领域得分与较低的 HAC 发生率有不同程度的相关性,其中与非惩罚性、开放式沟通相关的领域得分一直具有显著的相关性(P's < 0.05):我们相对可靠的研究结果表明,虽然患者安全文化可能不是提高 HAC 发生率的唯一必要策略,但它需要与其他提高质量和安全性的工作相结合。这强调了培养心理安全文化、促进公开反馈和错误沟通的重要性。
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引用次数: 0
Intraprocedural Fall of an Obese Patient During an Interventional Radiology Procedure. 一名肥胖患者在介入放射手术过程中的术中摔倒。
IF 1.7 3区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2024-12-01 Epub Date: 2024-07-22 DOI: 10.1097/PTS.0000000000001261
Brian Liu, Shayan Sadiq, Helen Wang, Estele Odo de Barros, Zhuoxuan Li, Kevin Nguyen, Sujai Jaipalli, Molly Li, Robert P Liddell
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引用次数: 0
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Journal of Patient Safety
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