Pub Date : 2012-06-01Epub Date: 2012-08-12DOI: 10.1177/1084713812454225
Valeriy Shafiro, Stanley Sheft, Brian Gygi, Kim Thien N Ho
Perceptual training with spectrally degraded environmental sounds results in improved environmental sound identification, with benefits shown to extend to untrained speech perception as well. The present study extended those findings to examine longer-term training effects as well as effects of mere repeated exposure to sounds over time. Participants received two pretests (1 week apart) prior to a week-long environmental sound training regimen, which was followed by two posttest sessions, separated by another week without training. Spectrally degraded stimuli, processed with a four-channel vocoder, consisted of a 160-item environmental sound test, word and sentence tests, and a battery of basic auditory abilities and cognitive tests. Results indicated significant improvements in all speech and environmental sound scores between the initial pretest and the last posttest with performance increments following both exposure and training. For environmental sounds (the stimulus class that was trained), the magnitude of positive change that accompanied training was much greater than that due to exposure alone, with improvement for untrained sounds roughly comparable to the speech benefit from exposure. Additional tests of auditory and cognitive abilities showed that speech and environmental sound performance were differentially correlated with tests of spectral and temporal-fine-structure processing, whereas working memory and executive function were correlated with speech, but not environmental sound perception. These findings indicate generalizability of environmental sound training and provide a basis for implementing environmental sound training programs for cochlear implant (CI) patients.
{"title":"The influence of environmental sound training on the perception of spectrally degraded speech and environmental sounds.","authors":"Valeriy Shafiro, Stanley Sheft, Brian Gygi, Kim Thien N Ho","doi":"10.1177/1084713812454225","DOIUrl":"https://doi.org/10.1177/1084713812454225","url":null,"abstract":"<p><p>Perceptual training with spectrally degraded environmental sounds results in improved environmental sound identification, with benefits shown to extend to untrained speech perception as well. The present study extended those findings to examine longer-term training effects as well as effects of mere repeated exposure to sounds over time. Participants received two pretests (1 week apart) prior to a week-long environmental sound training regimen, which was followed by two posttest sessions, separated by another week without training. Spectrally degraded stimuli, processed with a four-channel vocoder, consisted of a 160-item environmental sound test, word and sentence tests, and a battery of basic auditory abilities and cognitive tests. Results indicated significant improvements in all speech and environmental sound scores between the initial pretest and the last posttest with performance increments following both exposure and training. For environmental sounds (the stimulus class that was trained), the magnitude of positive change that accompanied training was much greater than that due to exposure alone, with improvement for untrained sounds roughly comparable to the speech benefit from exposure. Additional tests of auditory and cognitive abilities showed that speech and environmental sound performance were differentially correlated with tests of spectral and temporal-fine-structure processing, whereas working memory and executive function were correlated with speech, but not environmental sound perception. These findings indicate generalizability of environmental sound training and provide a basis for implementing environmental sound training programs for cochlear implant (CI) patients.</p>","PeriodicalId":48972,"journal":{"name":"Trends in Amplification","volume":"16 2","pages":"83-101"},"PeriodicalIF":0.0,"publicationDate":"2012-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1084713812454225","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30832621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-06-01Epub Date: 2012-06-13DOI: 10.1177/1084713812448547
Ming Zhang
Low-frequency otoacoustic emissions (OAEs) are often concealed by acoustic background noise such as those from a patient's breathing and from the environment during recording in clinics. When using electrocochleaography (ECochG or ECoG), such as cochlear microphonics (CMs), acoustic background noise do not contaminate the recordings. Our objective is to study the response pattern of CM waveforms (CMWs) to explore an alternative approach in assessing cochlear functions. In response to a 14-msec tone burst across several acoustic frequencies, CMWs were recorded at the ear canal from ten normal hearing subjects. A relatively long tone burst has a relatively narrow frequency band. The CMW amplitudes among different frequencies were compared. The CMW amplitudes among different frequencies were compared. Two features were observed in the response pattern of CMWs: the amplitude of CMWs decreased with an increase of stimulus frequency of the tone bursts; and such a decrease occurred at a faster rate at lower frequencies than at higher frequencies. Five factors as potential mechanisms for these features are proposed. Clinical applications such as hearing screening are discussed. Therefore, the response pattern of CMWs suggests that they may be used as an alternative to OAEs in the assessment of cochlear functions in the clinic, especially at low frequencies.
{"title":"Response pattern based on the amplitude of ear canal recorded cochlear microphonic waveforms across acoustic frequencies in normal hearing subjects.","authors":"Ming Zhang","doi":"10.1177/1084713812448547","DOIUrl":"https://doi.org/10.1177/1084713812448547","url":null,"abstract":"<p><p>Low-frequency otoacoustic emissions (OAEs) are often concealed by acoustic background noise such as those from a patient's breathing and from the environment during recording in clinics. When using electrocochleaography (ECochG or ECoG), such as cochlear microphonics (CMs), acoustic background noise do not contaminate the recordings. Our objective is to study the response pattern of CM waveforms (CMWs) to explore an alternative approach in assessing cochlear functions. In response to a 14-msec tone burst across several acoustic frequencies, CMWs were recorded at the ear canal from ten normal hearing subjects. A relatively long tone burst has a relatively narrow frequency band. The CMW amplitudes among different frequencies were compared. The CMW amplitudes among different frequencies were compared. Two features were observed in the response pattern of CMWs: the amplitude of CMWs decreased with an increase of stimulus frequency of the tone bursts; and such a decrease occurred at a faster rate at lower frequencies than at higher frequencies. Five factors as potential mechanisms for these features are proposed. Clinical applications such as hearing screening are discussed. Therefore, the response pattern of CMWs suggests that they may be used as an alternative to OAEs in the assessment of cochlear functions in the clinic, especially at low frequencies.</p>","PeriodicalId":48972,"journal":{"name":"Trends in Amplification","volume":"16 2","pages":"117-26"},"PeriodicalIF":0.0,"publicationDate":"2012-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1084713812448547","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30689023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-06-01Epub Date: 2012-08-23DOI: 10.1177/1084713812456906
Kostas Kokkinakis, Behnam Azimi, Yi Hu, David R Friedland
To restore hearing sensation, cochlear implants deliver electrical pulses to the auditory nerve by relying on sophisticated signal processing algorithms that convert acoustic inputs to electrical stimuli. Although individuals fitted with cochlear implants perform well in quiet, in the presence of background noise, the speech intelligibility of cochlear implant listeners is more susceptible to background noise than that of normal hearing listeners. Traditionally, to increase performance in noise, single-microphone noise reduction strategies have been used. More recently, a number of approaches have suggested that speech intelligibility in noise can be improved further by making use of two or more microphones, instead. Processing strategies based on multiple microphones can better exploit the spatial diversity of speech and noise because such strategies rely mostly on spatial information about the relative position of competing sound sources. In this article, we identify and elucidate the most significant theoretical aspects that underpin single- and multi-microphone noise reduction strategies for cochlear implants. More analytically, we focus on strategies of both types that have been shown to be promising for use in current-generation implant devices. We present data from past and more recent studies, and furthermore we outline the direction that future research in the area of noise reduction for cochlear implants could follow.
{"title":"Single and multiple microphone noise reduction strategies in cochlear implants.","authors":"Kostas Kokkinakis, Behnam Azimi, Yi Hu, David R Friedland","doi":"10.1177/1084713812456906","DOIUrl":"https://doi.org/10.1177/1084713812456906","url":null,"abstract":"<p><p>To restore hearing sensation, cochlear implants deliver electrical pulses to the auditory nerve by relying on sophisticated signal processing algorithms that convert acoustic inputs to electrical stimuli. Although individuals fitted with cochlear implants perform well in quiet, in the presence of background noise, the speech intelligibility of cochlear implant listeners is more susceptible to background noise than that of normal hearing listeners. Traditionally, to increase performance in noise, single-microphone noise reduction strategies have been used. More recently, a number of approaches have suggested that speech intelligibility in noise can be improved further by making use of two or more microphones, instead. Processing strategies based on multiple microphones can better exploit the spatial diversity of speech and noise because such strategies rely mostly on spatial information about the relative position of competing sound sources. In this article, we identify and elucidate the most significant theoretical aspects that underpin single- and multi-microphone noise reduction strategies for cochlear implants. More analytically, we focus on strategies of both types that have been shown to be promising for use in current-generation implant devices. We present data from past and more recent studies, and furthermore we outline the direction that future research in the area of noise reduction for cochlear implants could follow.</p>","PeriodicalId":48972,"journal":{"name":"Trends in Amplification","volume":"16 2","pages":"102-16"},"PeriodicalIF":0.0,"publicationDate":"2012-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1084713812456906","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30860815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-06-01Epub Date: 2012-07-11DOI: 10.1177/1084713812451159
Shu-Chen Peng, Monita Chatterjee, Nelson Lu
The present article reports on the perceptual weighting of prosodic cues in question-statement identification by adult cochlear implant (CI) listeners. Acoustic analyses of normal-hearing (NH) listeners' production of sentences spoken as questions or statements confirmed that in English the last bisyllabic word in a sentence carries the dominant cues (F0, duration, and intensity patterns) for the contrast. Furthermore, these analyses showed that the F0 contour is the primary cue for the question-statement contrast, with intensity and duration changes conveying important but less reliable information. On the basis of these acoustic findings, the authors examined adult CI listeners' performance in two question-statement identification tasks. In Task 1, 13 CI listeners' question-statement identification accuracy was measured using naturally uttered sentences matched for their syntactic structures. In Task 2, the same listeners' perceptual cue weighting in question-statement identification was assessed using resynthesized single-word stimuli, within which fundamental frequency (F0), intensity, and duration properties were systematically manipulated. Both tasks were also conducted with four NH listeners with full-spectrum and noise-band-vocoded stimuli. Perceptual cue weighting was assessed by comparing the estimated coefficients in logistic models fitted to the data. Of the 13 CI listeners, 7 achieved high performance levels in Task 1. The results of Task 2 indicated that multiple sources of acoustic cues for question-statement identification were utilized to different extents depending on the listening conditions (e.g., full spectrum vs. spectrally degraded) or the listeners' hearing and amplification status (e.g., CI vs. NH).
本文报告了成年人工耳蜗(CI)听者在识别问题陈述时对前音线索的感知权重。通过对听力正常(NH)的听者以疑问句或陈述句形式发出的句子进行声学分析,证实了在英语中,句子中的最后一个双音节词是对比的主要线索(F0、持续时间和强度模式)。此外,这些分析表明,F0 等高线是疑问句和陈述句对比的主要线索,而强度和持续时间的变化则传递着重要但不太可靠的信息。在这些声学发现的基础上,作者研究了成年 CI 听者在两个问题陈述识别任务中的表现。在任务 1 中,13 名 CI 听者使用句法结构匹配的自然句子来测量问题陈述识别的准确性。在任务 2 中,使用重新合成的单词刺激评估了同一听者在问题陈述识别中的知觉线索权重,在这些刺激中,基频 (F0)、强度和持续时间属性受到了系统性的操纵。这两项任务都是由四名 NH 听者使用全频谱和噪声带编码刺激进行的。通过比较与数据拟合的逻辑模型中的估计系数来评估知觉线索权重。在 13 名 CI 听力者中,有 7 人在任务 1 中取得了较高的成绩。任务 2 的结果表明,根据聆听条件(如全频谱与频谱衰减)或聆听者的听力和扩音状态(如 CI 与 NH),在不同程度上利用了多种声音线索来识别问题陈述。
{"title":"Acoustic cue integration in speech intonation recognition with cochlear implants.","authors":"Shu-Chen Peng, Monita Chatterjee, Nelson Lu","doi":"10.1177/1084713812451159","DOIUrl":"10.1177/1084713812451159","url":null,"abstract":"<p><p>The present article reports on the perceptual weighting of prosodic cues in question-statement identification by adult cochlear implant (CI) listeners. Acoustic analyses of normal-hearing (NH) listeners' production of sentences spoken as questions or statements confirmed that in English the last bisyllabic word in a sentence carries the dominant cues (F0, duration, and intensity patterns) for the contrast. Furthermore, these analyses showed that the F0 contour is the primary cue for the question-statement contrast, with intensity and duration changes conveying important but less reliable information. On the basis of these acoustic findings, the authors examined adult CI listeners' performance in two question-statement identification tasks. In Task 1, 13 CI listeners' question-statement identification accuracy was measured using naturally uttered sentences matched for their syntactic structures. In Task 2, the same listeners' perceptual cue weighting in question-statement identification was assessed using resynthesized single-word stimuli, within which fundamental frequency (F0), intensity, and duration properties were systematically manipulated. Both tasks were also conducted with four NH listeners with full-spectrum and noise-band-vocoded stimuli. Perceptual cue weighting was assessed by comparing the estimated coefficients in logistic models fitted to the data. Of the 13 CI listeners, 7 achieved high performance levels in Task 1. The results of Task 2 indicated that multiple sources of acoustic cues for question-statement identification were utilized to different extents depending on the listening conditions (e.g., full spectrum vs. spectrally degraded) or the listeners' hearing and amplification status (e.g., CI vs. NH).</p>","PeriodicalId":48972,"journal":{"name":"Trends in Amplification","volume":"16 2","pages":"67-82"},"PeriodicalIF":0.0,"publicationDate":"2012-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560417/pdf/10.1177_1084713812451159.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30757953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-03-01Epub Date: 2012-04-17DOI: 10.1177/1084713811434617
John F P Bridges, Angela T Lataille, Christine Buttorff, Sharon White, John K Niparko
Low utilization of hearing aids has drawn increased attention to the study of consumer preferences using both simple ratings (e.g., Likert scale) and conjoint analyses, but these two approaches often produce inconsistent results. The study aims to directly compare Likert scales and conjoint analysis in identifying important attributes associated with hearing aids among those with hearing loss. Seven attributes of hearing aids were identified through qualitative research: performance in quiet settings, comfort, feedback, frequency of battery replacement, purchase price, water and sweat resistance, and performance in noisy settings. The preferences of 75 outpatients with hearing loss were measured with both a 5-point Likert scale and with 8 paired-comparison conjoint tasks (the latter being analyzed using OLS [ordinary least squares] and logistic regression). Results were compared by examining implied willingness-to-pay and Pearson's Rho. A total of 56 respondents (75%) provided complete responses. Two thirds of respondents were male, most had sensorineural hearing loss, and most were older than 50; 44% of respondents had never used a hearing aid. Both methods identified improved performance in noisy settings as the most valued attribute. Respondents were twice as likely to buy a hearing aid with better functionality in noisy environments (p < .001), and willingness to pay for this attribute ranged from US$2674 on the Likert to US$9000 in the conjoint analysis. The authors find a high level of concordance between the methods-a result that is in stark contrast with previous research. The authors conclude that their result stems from constraining the levels on the Likert scale.
{"title":"Consumer preferences for hearing aid attributes: a comparison of rating and conjoint analysis methods.","authors":"John F P Bridges, Angela T Lataille, Christine Buttorff, Sharon White, John K Niparko","doi":"10.1177/1084713811434617","DOIUrl":"https://doi.org/10.1177/1084713811434617","url":null,"abstract":"<p><p>Low utilization of hearing aids has drawn increased attention to the study of consumer preferences using both simple ratings (e.g., Likert scale) and conjoint analyses, but these two approaches often produce inconsistent results. The study aims to directly compare Likert scales and conjoint analysis in identifying important attributes associated with hearing aids among those with hearing loss. Seven attributes of hearing aids were identified through qualitative research: performance in quiet settings, comfort, feedback, frequency of battery replacement, purchase price, water and sweat resistance, and performance in noisy settings. The preferences of 75 outpatients with hearing loss were measured with both a 5-point Likert scale and with 8 paired-comparison conjoint tasks (the latter being analyzed using OLS [ordinary least squares] and logistic regression). Results were compared by examining implied willingness-to-pay and Pearson's Rho. A total of 56 respondents (75%) provided complete responses. Two thirds of respondents were male, most had sensorineural hearing loss, and most were older than 50; 44% of respondents had never used a hearing aid. Both methods identified improved performance in noisy settings as the most valued attribute. Respondents were twice as likely to buy a hearing aid with better functionality in noisy environments (p < .001), and willingness to pay for this attribute ranged from US$2674 on the Likert to US$9000 in the conjoint analysis. The authors find a high level of concordance between the methods-a result that is in stark contrast with previous research. The authors conclude that their result stems from constraining the levels on the Likert scale.</p>","PeriodicalId":48972,"journal":{"name":"Trends in Amplification","volume":"16 1","pages":"40-8"},"PeriodicalIF":0.0,"publicationDate":"2012-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1084713811434617","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30583255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-03-01Epub Date: 2012-04-17DOI: 10.1177/1084713812440336
Takayuki Okano, Matthew W Kelley
In vertebrates, perception of sound, motion, and balance is mediated through mechanosensory hair cells located within the inner ear. In mammals, hair cells are only generated during a short period of embryonic development. As a result, loss of hair cells as a consequence of injury, disease, or genetic mutation, leads to permanent sensory deficits. At present, cochlear implantation is the only option for profound hearing loss. However, outcomes are still variable and even the best implant cannot provide the acuity of a biological ear. The recent emergence of stem cell technology has the potential to open new approaches for hair cell regeneration. The goal of this review is to summarize the current state of inner ear stem cell research from a viewpoint of its clinical application for inner ear disorders to illustrate how complementary studies have the potential to promote and refine stem cell therapies for inner ear diseases. The review initially discusses our current understanding of the genetic pathways that regulate hair cell formation from inner ear progenitors during normal development. Subsequent sections discuss the possible use of endogenous inner ear stem cells to induce repair as well as the initial studies aimed at transplanting stem cells into the ear.
{"title":"Stem cell therapy for the inner ear: recent advances and future directions.","authors":"Takayuki Okano, Matthew W Kelley","doi":"10.1177/1084713812440336","DOIUrl":"https://doi.org/10.1177/1084713812440336","url":null,"abstract":"<p><p>In vertebrates, perception of sound, motion, and balance is mediated through mechanosensory hair cells located within the inner ear. In mammals, hair cells are only generated during a short period of embryonic development. As a result, loss of hair cells as a consequence of injury, disease, or genetic mutation, leads to permanent sensory deficits. At present, cochlear implantation is the only option for profound hearing loss. However, outcomes are still variable and even the best implant cannot provide the acuity of a biological ear. The recent emergence of stem cell technology has the potential to open new approaches for hair cell regeneration. The goal of this review is to summarize the current state of inner ear stem cell research from a viewpoint of its clinical application for inner ear disorders to illustrate how complementary studies have the potential to promote and refine stem cell therapies for inner ear diseases. The review initially discusses our current understanding of the genetic pathways that regulate hair cell formation from inner ear progenitors during normal development. Subsequent sections discuss the possible use of endogenous inner ear stem cells to induce repair as well as the initial studies aimed at transplanting stem cells into the ear.</p>","PeriodicalId":48972,"journal":{"name":"Trends in Amplification","volume":"16 1","pages":"4-18"},"PeriodicalIF":0.0,"publicationDate":"2012-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1084713812440336","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30584295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-03-01Epub Date: 2011-12-04DOI: 10.1177/1084713811424884
Monique Boymans, Wouter A Dreschler
Two methods of fine tuning the initial settings of hearing aids were compared: An audiologist-driven approach--using real ear measurements and a patient-driven fine-tuning approach--using feedback from real-life situations. The patient-driven fine tuning was conducted by employing the Amplifit(®) II system using audiovideo clips. The audiologist-driven fine tuning was based on the NAL-NL1 prescription rule. Both settings were compared using the same hearing aids in two 6-week trial periods following a randomized blinded cross-over design. After each trial period, the settings were evaluated by insertion-gain measurements. Performance was evaluated by speech tests in quiet, in noise, and in time-reversed speech, presented at 0° and with spatially separated sound sources. Subjective results were evaluated using extensive questionnaires and audiovisual video clips. A total of 73 participants were included. On average, higher gain values were found for the audiologist-driven settings than for the patient-driven settings, especially at 1000 and 2000 Hz. Better objective performance was obtained for the audiologist-driven settings for speech perception in quiet and in time-reversed speech. This was supported by better scores on a number of subjective judgments and in the subjective ratings of video clips. The perception of loud sounds scored higher than when patient-driven, but the overall preference was in favor of the audiologist-driven settings for 67% of the participants.
{"title":"Audiologist-driven versus patient-driven fine tuning of hearing instruments.","authors":"Monique Boymans, Wouter A Dreschler","doi":"10.1177/1084713811424884","DOIUrl":"https://doi.org/10.1177/1084713811424884","url":null,"abstract":"<p><p>Two methods of fine tuning the initial settings of hearing aids were compared: An audiologist-driven approach--using real ear measurements and a patient-driven fine-tuning approach--using feedback from real-life situations. The patient-driven fine tuning was conducted by employing the Amplifit(®) II system using audiovideo clips. The audiologist-driven fine tuning was based on the NAL-NL1 prescription rule. Both settings were compared using the same hearing aids in two 6-week trial periods following a randomized blinded cross-over design. After each trial period, the settings were evaluated by insertion-gain measurements. Performance was evaluated by speech tests in quiet, in noise, and in time-reversed speech, presented at 0° and with spatially separated sound sources. Subjective results were evaluated using extensive questionnaires and audiovisual video clips. A total of 73 participants were included. On average, higher gain values were found for the audiologist-driven settings than for the patient-driven settings, especially at 1000 and 2000 Hz. Better objective performance was obtained for the audiologist-driven settings for speech perception in quiet and in time-reversed speech. This was supported by better scores on a number of subjective judgments and in the subjective ratings of video clips. The perception of loud sounds scored higher than when patient-driven, but the overall preference was in favor of the audiologist-driven settings for 67% of the participants.</p>","PeriodicalId":48972,"journal":{"name":"Trends in Amplification","volume":"16 1","pages":"49-58"},"PeriodicalIF":0.0,"publicationDate":"2012-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1084713811424884","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30304792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-03-01DOI: 10.1177/1084713812447737
Charles J Limb
The clinical treatment of hearing loss is at once sophisticated and crude. Surgeons can use microsurgical techniques and lasers to manipulate ossicular prostheses fractions of a millimeter with often astounding improvement in hearing, for example, in the case of stapes fixation due to otosclerosis. For profound sensorineural impairment, the cochlea may be surgically implanted with an electrode that stimulates the spiral ganglion neurons of the cochlea, thereby enabling effective hearing for many people. Yet despite modern surgical techniques and scientific advances, outcomes for restoration of conductive hearing when there is no ossicular chain at all remain unpredictable at best. Cochlear implants are threaded into the cochlea with very little precision as to which neurons are stimulated by which electrodes. In addition, not a single surgical intervention will help the typical patient with tinnitus, for whom even sectioning of the auditory nerve would not provide relief. Scalpels and drills can only do so much. Roughly, the same situation exists for current hearing aid technology. The historical evolution of assistive hearing devices, from the lowly ear trumpet to the modern digital hearing aid, provides irrefutable evidence of progress. For many patients, a simple hearing aid properly fitted can be life changing. However, as the severity of hearing loss worsens, hearing aid limitations become increasingly clear—for the patient with poor discrimination, for example, even the most powerful amplification available provides a fundamentally impoverished version of the auditory world. In other words, conventional amplification can be both remarkably helpful and glaringly insufficient. The more demanding a patient’s auditory needs are, the clearer the limitations in our methods of intervention often appear. It is quite plausible that molecular biology, rather than surgery or amplification, holds the key for the next transformative leap forward in our ability to treat hearing loss. As the review article (“Stem Cell Therapy for the Inner Ear: Recent Advances and Future Directions”) in this issue by Okano and Kelley suggests, a great deal of research has been done in the field of stem cells for the inner ear. This field has progressed in a relatively short span of time from an intriguing area of hypothetical inquiry to a viable possibility in the not-too-distant horizon. Scientists are truly starting to unravel the mysteries of hair cells and what it would take to regenerate them in humans. Through the development of stem cell therapy for the inner ear, it is becoming increasingly plausible that our future treatments for sensorineural hearing loss will be based on neither surgery nor hearing aids, but instead on molecular stem cell therapy. As the name suggests, stem cells offer the potential to bring the inner ear back to life, as it were, by restoring pluripotency to the cells of the inner ear—a critical step toward the reestablishment of hair ce
{"title":"When inner ear stem cell therapy becomes a reality.","authors":"Charles J Limb","doi":"10.1177/1084713812447737","DOIUrl":"https://doi.org/10.1177/1084713812447737","url":null,"abstract":"The clinical treatment of hearing loss is at once sophisticated and crude. Surgeons can use microsurgical techniques and lasers to manipulate ossicular prostheses fractions of a millimeter with often astounding improvement in hearing, for example, in the case of stapes fixation due to otosclerosis. For profound sensorineural impairment, the cochlea may be surgically implanted with an electrode that stimulates the spiral ganglion neurons of the cochlea, thereby enabling effective hearing for many people. Yet despite modern surgical techniques and scientific advances, outcomes for restoration of conductive hearing when there is no ossicular chain at all remain unpredictable at best. Cochlear implants are threaded into the cochlea with very little precision as to which neurons are stimulated by which electrodes. In addition, not a single surgical intervention will help the typical patient with tinnitus, for whom even sectioning of the auditory nerve would not provide relief. Scalpels and drills can only do so much. \u0000 \u0000Roughly, the same situation exists for current hearing aid technology. The historical evolution of assistive hearing devices, from the lowly ear trumpet to the modern digital hearing aid, provides irrefutable evidence of progress. For many patients, a simple hearing aid properly fitted can be life changing. However, as the severity of hearing loss worsens, hearing aid limitations become increasingly clear—for the patient with poor discrimination, for example, even the most powerful amplification available provides a fundamentally impoverished version of the auditory world. In other words, conventional amplification can be both remarkably helpful and glaringly insufficient. The more demanding a patient’s auditory needs are, the clearer the limitations in our methods of intervention often appear. \u0000 \u0000It is quite plausible that molecular biology, rather than surgery or amplification, holds the key for the next transformative leap forward in our ability to treat hearing loss. As the review article (“Stem Cell Therapy for the Inner Ear: Recent Advances and Future Directions”) in this issue by Okano and Kelley suggests, a great deal of research has been done in the field of stem cells for the inner ear. This field has progressed in a relatively short span of time from an intriguing area of hypothetical inquiry to a viable possibility in the not-too-distant horizon. Scientists are truly starting to unravel the mysteries of hair cells and what it would take to regenerate them in humans. Through the development of stem cell therapy for the inner ear, it is becoming increasingly plausible that our future treatments for sensorineural hearing loss will be based on neither surgery nor hearing aids, but instead on molecular stem cell therapy. As the name suggests, stem cells offer the potential to bring the inner ear back to life, as it were, by restoring pluripotency to the cells of the inner ear—a critical step toward the reestablishment of hair ce","PeriodicalId":48972,"journal":{"name":"Trends in Amplification","volume":"16 1","pages":"3"},"PeriodicalIF":0.0,"publicationDate":"2012-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1084713812447737","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30623817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2012-03-01DOI: 10.1177/1084713812445510
Joseph G Desloge, Charlotte M Reed, Louis D Braida, Zachary D Perez, Lorraine A Delhorne
Functional simulation of sensorineural hearing impairment is an important research tool that can elucidate the nature of hearing impairments and suggest or eliminate compensatory signal-processing schemes. The objective of the current study was to evaluate the capability of an audibility-based functional simulation of hearing loss to reproduce the auditory-filter characteristics of listeners with sensorineural hearing loss. The hearing-loss simulation used either threshold-elevating noise alone or a combination of threshold-elevating noise and multiband expansion to reproduce the audibility-based characteristics of the loss (including detection thresholds, dynamic range, and loudness recruitment). The hearing losses of 10 listeners with bilateral, mild-to-severe hearing loss were simulated in 10 corresponding groups of 3 age-matched normal-hearing listeners. Frequency selectivity was measured using a notched-noise masking paradigm at five probe frequencies in the range of 250 to 4000 Hz with a fixed probe level of either 70 dB SPL or 8 dB SL (whichever was greater) and probe duration of 200 ms. The hearing-loss simulation reproduced the absolute thresholds of individual hearing-impaired listeners with an average root-mean-squared (RMS) difference of 2.2 dB and the notched-noise masked thresholds with an RMS difference of 5.6 dB. A rounded-exponential model of the notched-noise data was used to estimate equivalent rectangular bandwidths and slopes of the auditory filters. For some subjects and probe frequencies, the simulations were accurate in reproducing the auditory-filter characteristics of the hearing-impaired listeners. In other cases, however, the simulations underestimated the magnitude of the auditory bandwidths for the hearing-impaired listeners, which suggests the possibility of suprathreshold deficits.
{"title":"Auditory-filter characteristics for listeners with real and simulated hearing impairment.","authors":"Joseph G Desloge, Charlotte M Reed, Louis D Braida, Zachary D Perez, Lorraine A Delhorne","doi":"10.1177/1084713812445510","DOIUrl":"10.1177/1084713812445510","url":null,"abstract":"<p><p>Functional simulation of sensorineural hearing impairment is an important research tool that can elucidate the nature of hearing impairments and suggest or eliminate compensatory signal-processing schemes. The objective of the current study was to evaluate the capability of an audibility-based functional simulation of hearing loss to reproduce the auditory-filter characteristics of listeners with sensorineural hearing loss. The hearing-loss simulation used either threshold-elevating noise alone or a combination of threshold-elevating noise and multiband expansion to reproduce the audibility-based characteristics of the loss (including detection thresholds, dynamic range, and loudness recruitment). The hearing losses of 10 listeners with bilateral, mild-to-severe hearing loss were simulated in 10 corresponding groups of 3 age-matched normal-hearing listeners. Frequency selectivity was measured using a notched-noise masking paradigm at five probe frequencies in the range of 250 to 4000 Hz with a fixed probe level of either 70 dB SPL or 8 dB SL (whichever was greater) and probe duration of 200 ms. The hearing-loss simulation reproduced the absolute thresholds of individual hearing-impaired listeners with an average root-mean-squared (RMS) difference of 2.2 dB and the notched-noise masked thresholds with an RMS difference of 5.6 dB. A rounded-exponential model of the notched-noise data was used to estimate equivalent rectangular bandwidths and slopes of the auditory filters. For some subjects and probe frequencies, the simulations were accurate in reproducing the auditory-filter characteristics of the hearing-impaired listeners. In other cases, however, the simulations underestimated the magnitude of the auditory bandwidths for the hearing-impaired listeners, which suggests the possibility of suprathreshold deficits.</p>","PeriodicalId":48972,"journal":{"name":"Trends in Amplification","volume":"16 1","pages":"19-39"},"PeriodicalIF":0.0,"publicationDate":"2012-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040846/pdf/10.1177_1084713812445510.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30623818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2011-12-01Epub Date: 2012-03-07DOI: 10.1177/1084713812438700
Gitte Keidser, Harvey Dillon, Dan Zhou, Lyndal Carter
A self-fitting, self-contained hearing aid is a device that can be managed entirely by the user, without assistance from a hearing health care professional or the need for special equipment. A key component of such a device is an automated audiometer that will enable the user to self-administer measurements of in situ thresholds, which the hearing aid will use to prescribe a baseline setting for the wearer. The success of the device therefore depends on the validity and reliability of in situ threshold measurements and automatically measured thresholds. To produce a complete and self-contained device, the self-fitting hearing aid will also enable identification of audiograms that are contraindicative of hearing aid usage. The feasibility and challenges of achieving these characteristics are explored and discussed. While the overall concept seems feasible, several challenges were identified that need thorough investigation and/or development. These include the use of instructions to self-manage hearing aid insertion and in situ threshold measurements, selection of an appropriate transducer and instant-fit tip that will allow measurements of a wide range of threshold levels, control of ambient noise during threshold measurements, and self-manageable procedures that enable identification of such audiogram characteristics as asymmetry and conductive hearing loss.
{"title":"Threshold measurements by self-fitting hearing aids: feasibility and challenges.","authors":"Gitte Keidser, Harvey Dillon, Dan Zhou, Lyndal Carter","doi":"10.1177/1084713812438700","DOIUrl":"https://doi.org/10.1177/1084713812438700","url":null,"abstract":"<p><p>A self-fitting, self-contained hearing aid is a device that can be managed entirely by the user, without assistance from a hearing health care professional or the need for special equipment. A key component of such a device is an automated audiometer that will enable the user to self-administer measurements of in situ thresholds, which the hearing aid will use to prescribe a baseline setting for the wearer. The success of the device therefore depends on the validity and reliability of in situ threshold measurements and automatically measured thresholds. To produce a complete and self-contained device, the self-fitting hearing aid will also enable identification of audiograms that are contraindicative of hearing aid usage. The feasibility and challenges of achieving these characteristics are explored and discussed. While the overall concept seems feasible, several challenges were identified that need thorough investigation and/or development. These include the use of instructions to self-manage hearing aid insertion and in situ threshold measurements, selection of an appropriate transducer and instant-fit tip that will allow measurements of a wide range of threshold levels, control of ambient noise during threshold measurements, and self-manageable procedures that enable identification of such audiogram characteristics as asymmetry and conductive hearing loss.</p>","PeriodicalId":48972,"journal":{"name":"Trends in Amplification","volume":" ","pages":"167-74"},"PeriodicalIF":0.0,"publicationDate":"2011-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1084713812438700","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40147138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}