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Poor reporting may infer poor science: lessons learned from asthma trials. 糟糕的报告可能会推断出糟糕的科学:从哮喘试验中吸取的教训。
Pub Date : 2013-12-01 DOI: 10.4104/pcrj.2013.00095
Jasper V Been, Daniel Kotz, Onno C P van Schayck
after real-life data suggests that ‘unplanned’ quit attempts are more successful than ‘planned’ ones. Hence the "catastrophe theory," where smokers have varying levels of motivational "tension" to stop, and then "triggers" in the environment result in a sudden switch in motivational state; if that switch involves immediate renunciation of cigarettes, this can signal a more complete transformation. Tailoring a visual tool to trigger a “catastrophic switch” may yield more benefits. Other visual tools could be developed for those who can’t or won’t immediately quit, which may be just as effective as abrupt quit dates. This pilot should be likened to a Phase 1 trial. Almost anything needing new skills and precious consultation time will encounter some resistance. This did not happen here, with a similar duration of counselling sessions and similar GPs’ ratings on practicability and usefulness. This is the crux of the study. The additional tool was well used. Like any good research, it opens up more questions and opportunities. It has passed Phase 1, so now is the time for Phase 2 and onwards. Their tool could be tried instead of the IPCRG tool. They could develop aids based on other prevalent illnesses, or aids for less motivated or difficult-to-reach smokers (those with mental illness, pregnant smokers, manual workers and ethnic minorities) where smoking rates and health inequalities continue to grow. NeunerJehle’s team needs to continue this work. As former Australian Health Minister Nicola Roxon has said, “We are killing people by not acting.”
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引用次数: 0
Patients' perceptions of the potential of breathing training for asthma: a qualitative study. 患者对哮喘呼吸训练潜力的认知:一项定性研究。
Pub Date : 2013-12-01 DOI: 10.4104/pcrj.2013.00092
Emily Arden-Close, Emma Teasdale, Sarah Tonkin-Crine, Natasha Pitre, Mark Stafford-Watson, Denise Gibson, Anne Bruton, Mike Thomas, Lucy Yardley

Background: Poor symptom control is common in asthma. Breathing training exercises may be an effective adjunct to medication; it is therefore important to understand facilitators and barriers to uptake of breathing training exercises.

Aims: To gain insight into patients' perceptions of breathing training exercises designed to help control asthma symptoms.

Methods: Semi-structured think-aloud interviews were conducted with 29 people with asthma about their views of a booklet on breathing training exercises.

Results: Thematic analysis showed breathing training exercises were seen as acceptable in principle because they were viewed as nonpharmacological, holistic, unobtrusive, and likely to increase patient confidence in managing symptoms. Anticipated disadvantages included the time required and perceived irrelevance for those with well-controlled asthma. These views were influenced by prior experience of changing breathing, wanting to self-manage asthma, negative views of medication, and perceived asthma control/severity. Anticipated barriers to carrying out the exercises included difficulties with nose breathing, remembering to do them, and persevering with them. Anticipated facilitators included monitoring tools and social support.

Conclusions: The idea of breathing training was viewed positively as an acceptable non-pharmacological treatment that patients can do discreetly to help them breathe more easily and reduce their reliance on medication. Uptake of breathing training may be greater among those who perceive their asthma as severe and/or have negative views of medication. To enhance uptake, it might be helpful to present breathing training exercises as holistic skills that can also benefit those with mild symptoms.

背景:症状控制不佳是哮喘的常见病。呼吸训练可能是药物治疗的有效辅助;因此,了解呼吸训练练习的促进因素和障碍是很重要的。目的:深入了解患者对旨在帮助控制哮喘症状的呼吸训练练习的看法。方法:对29例哮喘患者进行半结构化的有声思考访谈,询问他们对呼吸训练练习小册子的看法。结果:专题分析显示,呼吸训练练习在原则上被认为是可以接受的,因为它们被认为是非药物的,整体的,不引人注目的,并且可能增加患者对控制症状的信心。预期的缺点包括所需的时间和对那些控制良好的哮喘患者的感知无关。这些观点受到之前改变呼吸的经历、想要自我管理哮喘、对药物的负面看法以及感知到的哮喘控制/严重程度的影响。进行这些练习的预期障碍包括鼻子呼吸困难、记住做这些练习和坚持做这些练习。预期的促进因素包括监测工具和社会支持。结论:呼吸训练的想法被积极地视为一种可接受的非药物治疗,患者可以谨慎地帮助他们更轻松地呼吸,减少对药物的依赖。在那些认为自己的哮喘很严重和/或对药物有负面看法的人中,呼吸训练的吸收可能更大。为了增强吸收,将呼吸训练练习作为整体技能来呈现可能会有所帮助,这对那些症状轻微的人也有好处。
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引用次数: 18
The debated problem of community-acquired pneumonia diagnosis: many guidelines, any guideline? 社区获得性肺炎诊断的争议问题:准则多,准则少?
Pub Date : 2013-12-01 DOI: 10.4104/pcrj.2013.00096
Antonio Infantino, Ruben Infantino
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引用次数: 0
Journalwatch@pcrj
Pub Date : 2013-11-29 DOI: 10.4104/pcrj.2013.00101
Here's the best of the rest: summary reviews of relevant papers from the top respiratory and general medical journals worldwide. Journalwatch@pcrj is produced by the PCRJ Editors-in-Chief — reviews were selected and written by Dr Paul Stephenson and edited by Professor Aziz Sheikh. Each summary contains the name of the first author, the title of the paper, the Vancouver reference and/or doi number, and a link to the abstract of the paper. In the majority of cases these are subscription journals, so to view the full text you will need to subscribe to the journal or pay to view on an individual article basis. These reviews were originally published by the Doctors.net.uk Journal Watch service, which covers other specialties as well as respiratory medicine. Doctors.net.uk is the largest network of GMC-registered doctors in the UK. To find out about membership, click on Doctors.net.uk. The opinions expressed herein may not necessarily reflect the views of the authors of the original articles.
以下是最好的:来自全球顶级呼吸和普通医学期刊的相关论文综述。Journalwatch@pcrj由PCRJ总编辑制作,评论由Paul Stephenson博士选择和撰写,Aziz Sheikh教授编辑。每个摘要包含第一作者的姓名,论文的标题,温哥华参考文献和/或doi号,以及论文摘要的链接。在大多数情况下,这些都是订阅期刊,所以要查看全文,你需要订阅期刊或付费查看个别文章。这些评论最初发表在Doctors.net.uk杂志观察服务上,该服务涵盖了其他专业以及呼吸医学。Doctors.net.uk是英国最大的gmc注册医生网络。要了解会员资格,请点击Doctors.net.uk。这里表达的观点不一定反映原始文章作者的观点。
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引用次数: 0
Selected abstracts from the PCRS-UK National Primary Care Respiratory Conference, Telford, October 2013 选自2013年10月在特尔福德举行的PCRS-UK全国初级保健呼吸会议
Pub Date : 2013-11-28 DOI: 10.4104/pcrj.2013.00105
Selected abstracts from the PCRS-UK National Primary Care Respiratory Conference, Telford, October 2013 A1 PRIMARY CARE RESPIRATORY JOURNAL www.thepcrj.org http://dx.doi.org/10.4104/pcrj.2013.00105 1. Patient reported satisfaction of a proactive post hospital discharge telephone service in patients with Chronic Obstructive Pulmonary Disease Bahadur KJ, Chauhan D, McDonnell L, Osman L Physiotherapy Department, Guy’s and St. Thomas’ NHS Foundation Trust (GSTFT), London, UK Aim: Background: Although post hospital discharge telephone support (PHDTS) is a common feature of many clinical services there is little published evidence evaluating the benefits in patients admitted with an exacerbation of chronic obstructive pulmonary disease (ECOPD). Recently GSTFT introduced proactive telephone support as part of routine post-discharge care in the community for patients admitted with an ECOPD. PHDTS was provided weekly for the first month and monthly for two months thereafter. Aim: To evaluate a pro-active PHDTS service by determining patient satisfaction. Method: A patient satisfaction survey was developed with the Patient Experience Team. A convenience sample of 22 patients who received PHDTS during December 2011 was used. Patients were contacted by a single member of the Integrated Respiratory Team (IRT) and the survey completed over the telephone. Results: 21/22 (95%) patients completed the patient survey. 70% rated it “very useful” and 25% “good”. Patients reported that calls were made at convenient times, appropriate frequencies and that regular contact with staff was useful. 67% of patients thought that PHDTS helped to prevent them from visiting hospital. 71% of patients thought that PHDTS decreased their need to contact their GP. Conclusion: Patient satisfaction was high. PHDTS may augment selfmanagement strategies which can help to improve outcome. This survey suggests that pro-active PHDTS is effective in the management of patients with COPD. This could potentially reduce primary and secondary care attendances and healthcare utilisation. Conflict of interest and funding: Nil Corresponding author: Mr Kristopher Bahadur Email: kris.bahadur@gstt.nhs.uk Phone: 07967707472 Institution: Guy's and St. Thomas' NHS Foundation Trust Westminster Bridge Road London United Kingdom SE1 7EH 2. Step-down of well-controlled paediatric asthma patients in primary care: A pharmacist led primary care service Bhalla MK, Abdalla H Walsall Medicines Management, Walsall Clinical Commissioning Group (CCG) Brief outline of context: A pharmacist independent prescriber undertook a pilot project in two practices to identify well-controlled paediatric asthma patients and safely step-down their treatments Brief outline of problem: Accurately diagnosing asthma in children can be difficult leading to some receiving inappropriate diagnoses. Moreover, many young asthmatics outgrow their condition. Nevertheless, a structured step-down is seldom offered to these patients. Assessment o
选自PCRS-UK国家初级保健呼吸会议,Telford, 2013年10月A1初级保健呼吸杂志www.thepcrj.org http://dx.doi.org/10.4104/pcrj.2013.00105 1。Bahadur KJ, Chauhan D, McDonnell L, Osman L英国伦敦盖伊和圣托马斯NHS基金会信托(GSTFT)物理治疗科患者对慢性阻塞性肺病患者积极出院后电话服务的满意度虽然出院后电话支持(PHDTS)是许多临床服务的共同特征,但很少有公开的证据评估慢性阻塞性肺疾病(ECOPD)加重患者入院时的益处。最近,GSTFT将积极主动的电话支持作为ECOPD入院患者社区常规出院后护理的一部分。第一个月每周提供PHDTS,之后两个月每月提供PHDTS。目的:通过确定患者满意度来评价积极主动的PHDTS服务。方法:与患者体验组开展患者满意度调查。选取2011年12月期间接受PHDTS治疗的22例患者作为方便样本。综合呼吸小组(IRT)的一名成员与患者联系,并通过电话完成调查。结果:21/22(95%)患者完成患者调查。70%的人认为“非常有用”,25%的人认为“好”。病人报告说,打电话的时间方便,频率合适,与工作人员的定期联系是有用的。67%的患者认为医生培训有助于阻止他们去医院。71%的患者认为PHDTS减少了他们联系全科医生的需求。结论:患者满意度高。PHDTS可以增强自我管理策略,有助于改善结果。本研究提示,主动PHDTS在COPD患者的治疗中是有效的。这可能会降低初级和二级保健的出勤率和医疗保健的利用率。利益冲突和资助:无通讯作者:christopher Bahadur先生电子邮件:kris.bahadur@gstt.nhs.uk电话:07967707472机构:盖伊和圣托马斯NHS基金会信托英国伦敦威斯敏斯特桥路SE1 7EH 2。一名药剂师领导的初级保健服务机构Bhalla MK, Abdalla H Walsall药品管理公司,Walsall临床委托小组(CCG)简要背景概述:一名药剂师独立开处方者在两个实践中开展了一个试点项目,以确定控制良好的儿科哮喘患者并安全地减少他们的治疗。准确诊断儿童哮喘可能很困难,导致一些人接受不适当的诊断。此外,许多年轻的哮喘患者长大后病情就好转了。然而,对这些患者来说,很少有组织的退步。问题评估和原因分析:Asthma UK报告了110万哮喘儿童,但关于有多少儿童适合逐步减少治疗或如何安全地进行治疗的信息很少。改变策略:一名药剂师对选定的患者进行了咨询,以便:•审查药物•检查吸入器技术,•进行哮喘控制测试(ACT)•发布自我管理计划•对合适的患者实施治疗降级药剂师在6-8周后进行了电话咨询。改善的测量:每周根据出勤率和病人出院的数量对方法进行审查。对于这些患者,在随访时再次记录ACT分数。改变的影响:25例患者被观察和审查,所有患者都有一致性问题。其中14个(56%)被淘汰,每月节省103.55英镑。所有停止治疗的患者随访ACT得分相同或更高,表明哮喘得到了持续控制。经验教训:结果突出了目前为控制良好的儿科哮喘患者停止治疗提供服务的差距。给其他人的信息:许多被诊断患有哮喘的儿童可以由训练有素的药剂师安全地退场,同时巩固一致性并节省成本。利益冲突和资金:无通讯作者:Ms Mindy Bhalla电子邮件:Mindy.bhalla@walsall.nhs.uk电话:07843428487机构:Walsall临床调试组Bloxwich lane Jubilee house Walsall United Kingdom Ws27jl 3。二级医疗是造成COPD患者高额医疗费用的罪魁祸首吗?目标:用于慢性阻塞性肺病患者的医疗费用超过9亿英镑,其中三分之二以上是在二级保健中遇到的。
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引用次数: 1
Sensitisation patterns and association with age, gender, and clinical symptoms in children with allergic rhinitis in primary care: a cross-sectional study. 初级保健中过敏性鼻炎患儿的致敏模式及其与年龄、性别和临床症状的关系:一项横断面研究
Pub Date : 2013-06-01 DOI: 10.4104/pcrj.2013.00015
Cindy M A de Bot, Esther Röder, David H J Pols, Patrick J E Bindels, Roy Gerth van Wijk, Johannes C van der Wouden, Heleen Moed

Background: Polysensitisation is a frequent phenomenon in patients with allergic rhinitis. However, few studies have investigated the characteristics of polysensitised children, especially in primary care.

Objectives: This analysis describes the patterns of sensitisation to common allergens and the association with age, gender, and clinical symptoms in children in primary care diagnosed with allergic rhinitis.

Methods: Cross-sectional data from two randomised double-blind placebo-controlled studies were used to select children aged 6-18 years (n=784) with a doctor's diagnosis of allergic rhinitis or use of relevant medication for allergic rhinitis in primary care. They were assessed for age, gender, specific IgE (type and number of sensitisations), nasal and eye symptom scores.

Results: In 699 of the 784 children (89%) with a doctor's diagnosis or relevant medication use, a positive IgE test for one or more allergens was found. Polysensitisation (>2 sensitisations) was found in 69% of all children. Sensitisation was more common in children aged 9-13 than in younger children aged 5-8 years (p=0.03). Monosensitisation and polysensitisation were not significantly different in girls and boys. The severity of clinical symptoms did not differ between polysensitised and monosensitised children, but symptoms were significantly lower in non-sensitised children.

Conclusions: Polysensitisation to multiple allergens occurs frequently in children with allergic rhinitis in general practice. Overall, clinical symptoms are equally severe in polysensitised and monosensitised children. Treatment decisions for allergic rhinitis should be made on the basis of a clinical history and allergy testing.

背景:多致敏是变应性鼻炎患者的常见现象。然而,很少有研究调查多致敏儿童的特征,特别是在初级保健中。目的:本分析描述了在初级保健诊断为过敏性鼻炎的儿童对常见过敏原的致敏模式及其与年龄、性别和临床症状的关系。方法:采用两项随机双盲安慰剂对照研究的横断面数据,选择6-18岁的儿童(n=784),这些儿童被医生诊断为变应性鼻炎或在初级保健中使用相关药物治疗变应性鼻炎。评估他们的年龄、性别、特异性IgE(致敏类型和数量)、鼻和眼症状评分。结果:784名儿童中有699名(89%)经医生诊断或使用相关药物,发现一种或多种过敏原的IgE检测呈阳性。69%的儿童出现多致敏(>2次致敏)。致敏在9-13岁的儿童中比5-8岁的儿童更常见(p=0.03)。单致敏和多致敏在女孩和男孩中无显著差异。多致敏和单致敏儿童的临床症状严重程度无差异,但非致敏儿童的症状明显较低。结论:对多种过敏原的多致敏在儿童变应性鼻炎中常见。总的来说,多致敏和单致敏儿童的临床症状同样严重。过敏性鼻炎的治疗决定应基于临床病史和过敏试验。
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引用次数: 21
Evaluation of patients with symptoms of chronic lung disease in primary care. 初级保健对慢性肺部疾病症状患者的评价
Pub Date : 2013-06-01 DOI: 10.4104/pcrj.2013.00054
Guy B Marks
s presented elsewhere will be accepted MERGED Editorials 2 web 29/5/13 17:23 Page 9
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引用次数: 1
Using the DOSE index to predict changes in health status of patients with COPD: a prospective cohort study. 使用剂量指数预测COPD患者健康状况的变化:一项前瞻性队列研究
Pub Date : 2013-06-01 DOI: 10.4104/pcrj.2013.00033
Myrte Rolink, Wouter van Dijk, Saskia van den Haak-Rongen, Willem Pieters, Tjard Schermer, Lisette van den Bemt

Background: The severity of chronic obstructive pulmonary disease (COPD) should not be based on the level of airflow limitation alone. A multicomponent index such as the DOSE index (dyspnoea score (D), level of airflow obstruction (O), current smoking status (S), and exacerbations (E)) has the potential to predict important future outcomes in patients with COPD more effectively than the forced expiratory volume in one second. Health status deterioration should be prevented in COPD patients.

Aims: To investigate whether the DOSE index can predict which patients are at risk of a clinically relevant change in health status.

Methods: A prospective cohort study was performed using data from primary and secondary care. The DOSE score was determined at baseline and the 2-year change in the Clinical COPD Questionnaire (CCQ) score was calculated. Linear regression analysis was performed for the effect of a high DOSE score (≥ 4) on the change in CCQ score.

Results: The study population consisted of 209 patients (112 patients from primary care). Overall, a high DOSE score was a significant predictor of a change in CCQ score after 2 years (0.41, 95% CI 0.13 to 0.70), particularly in primary care patients.

Conclusions: A DOSE score of ≥ 4 has the ability to identify COPD patients with a greater risk of future worsening in health status.

背景:慢性阻塞性肺疾病(COPD)的严重程度不应仅基于气流限制的水平。多组分指数,如DOSE指数(呼吸困难评分(D)、气流阻塞水平(O)、当前吸烟状况(S)和恶化情况(E)),比一秒用力呼气量更有效地预测COPD患者重要的未来结局。COPD患者应预防健康状况恶化。目的:探讨剂量指数是否可以预测哪些患者有临床相关健康状况改变的风险。方法:采用来自初级和二级保健的数据进行前瞻性队列研究。在基线时确定DOSE评分,并计算临床COPD问卷(CCQ)评分的2年变化。采用线性回归分析高DOSE评分(≥4)对CCQ评分变化的影响。结果:研究人群包括209例患者(112例来自初级保健)。总体而言,高剂量评分是2年后CCQ评分变化的重要预测因子(0.41,95% CI 0.13至0.70),特别是在初级保健患者中。结论:剂量评分≥4能够识别COPD患者未来健康状况恶化的风险更大。
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引用次数: 25
Expanding nurse practice in COPD: is it key to providing high quality, effective and safe patient care? 扩大慢性阻塞性肺病护理实践:提供高质量、有效和安全的患者护理的关键吗?
Pub Date : 2013-06-01 DOI: 10.4104/pcrj.2013.00044
Monica J Fletcher, Birthe H Dahl

The prevalence of chronic obstructive pulmonary disease (COPD), a common and preventable chronic disease, is on the increase, and so are the financial and social burdens associated with it. The management of COPD is particularly challenging, as patients have complex health and social needs requiring life-long monitoring and treatment. In order to address these issues and reduce the burden imposed by COPD, the development of innovative disease management models is vital. Nurses are in a key position to assume a leading role in the management of COPD since they frequently represent the first point of contact for patients and are involved in all stages of care. Although evidence is still limited, an increasing number of studies have suggested that nurse-led consultations and interventions for the management of COPD have the potential to impact positively on the health and quality of life of patients. The role of nurses in the management of COPD around the world could be significantly expanded and strengthened. Providing adequate educational opportunities and support to nurses, as well as addressing funding issues and system barriers and recognising the importance of the expanding roles of nurses, is vital to the well-being of patients with long-term medical conditions such as COPD and to society as a whole, in order to reduce the burden of this disease.

慢性阻塞性肺疾病(COPD)是一种常见且可预防的慢性疾病,其患病率正在上升,与之相关的经济和社会负担也在增加。慢性阻塞性肺病的管理尤其具有挑战性,因为患者有复杂的健康和社会需求,需要终身监测和治疗。为了解决这些问题并减轻慢性阻塞性肺病带来的负担,开发创新的疾病管理模式至关重要。护士在慢性阻塞性肺病的管理中处于关键地位,因为她们经常是患者的第一个接触点,并参与护理的所有阶段。尽管证据仍然有限,但越来越多的研究表明,护士主导的慢性阻塞性肺病管理咨询和干预措施有可能对患者的健康和生活质量产生积极影响。护士在世界各地慢性阻塞性肺病管理中的作用可以显著扩大和加强。为护士提供充分的教育机会和支持,以及解决资金问题和制度障碍,并认识到护士扩大作用的重要性,对于慢性阻塞性肺病等长期疾病患者的福祉和整个社会的福祉至关重要,以便减轻这种疾病的负担。
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引用次数: 56
Asthma in the workplace: a case-based discussion and review of current evidence. 工作场所的哮喘:基于案例的讨论和对现有证据的回顾。
Pub Date : 2013-06-01 DOI: 10.4104/pcrj.2013.00038
David Fishwick, Chris Barber, Samantha Walker, Alister Scott

The relationship between asthma and the workplace is important to consider in all cases of adult asthma. Early identification of a cause in the workplace offers an opportunity to improve asthma control significantly and reduce the need for long-term medication if further exposures to the cause can be avoided. This typical but fictitious case is designed to give the reader clinical information in the order this would normally be received in clinical practice, with a real-time commentary about management decisions. Pertinent recent guidance is cited to stress the importance of evidence-based practice.

在所有成人哮喘病例中,哮喘和工作场所之间的关系都是重要的考虑因素。在工作场所及早发现病因,如果能够避免进一步接触病因,就有机会显著改善哮喘控制,并减少长期用药的需要。这个典型但虚构的病例旨在按照临床实践中通常收到的顺序向读者提供临床信息,并对管理决策进行实时评论。引用最近的相关指南来强调循证实践的重要性。
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引用次数: 8
期刊
Primary Care Respiratory Journal
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