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Challenges in Management of Uncommon Otologic Fungal Disease - a Case Series and Review of Literature. 治疗不常见耳部真菌病的挑战--一个病例系列和文献综述。
IF 0.6 Q4 SURGERY Pub Date : 2024-12-01 Epub Date: 2024-08-24 DOI: 10.1007/s12070-024-04989-x
Mallory Peters, Rusella Mirza, Areli Cuevas-Ocampo, Gauri Mankekar

The purpose of this study is to describe challenges in diagnosis and treatment of otologic fungal infections.; 2) Methods: Case series and literature review 3) Results: Three patients treated at Louisiana State University Health Sciences Center - Shreveport between November 2020 - November 2023 were identified with complicated fungal otitis externa requiring detailed radiologic and histopathologic workup to aid in diagnosis and management. 4) Conclusion: Diagnosis of otologic fungal infection is often complex due to similar presentation of more common pathogens, overlapping features among common fungal specimens, and limitations of available diagnostic methods. Patient factors, including diabetes with poor glycemic control, may further complicate this challenging disease. High index of clinical suspicion, collaboration between multidisciplinary teams is essential to differentiate between common and uncommon fungal ear infections. A combination of mechanical debridement, topical and/or systemic therapy, and longitudinal follow-up with otolaryngology and infectious disease teams is required for successful treatment.

本研究旨在描述耳科真菌感染的诊断和治疗难题;2)方法:病例系列和文献综述 3) 结果:2020 年 11 月至 2023 年 11 月期间,在路易斯安那州立大学健康科学中心-什里夫波特分中心接受治疗的三名患者被确认患有复杂的真菌性外耳道炎,需要进行详细的放射学和组织病理学检查以帮助诊断和治疗。4) 结论:耳部真菌感染的诊断通常比较复杂,这是因为常见病原体的表现形式相似,常见真菌标本的特征重叠,以及现有诊断方法的局限性。患者因素(包括血糖控制不佳的糖尿病)可能会使这一具有挑战性的疾病进一步复杂化。临床高度怀疑、多学科团队合作对于区分常见和不常见真菌性耳部感染至关重要。成功治疗需要结合机械清创、局部和/或全身治疗,以及耳鼻喉科和传染病团队的长期随访。
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引用次数: 0
Ceruminous Adenoma: A Case Report and Review of Literature. Ceruminous Adenoma: A Case Report and Review of Literature.
IF 0.6 Q4 SURGERY Pub Date : 2024-12-01 Epub Date: 2024-09-02 DOI: 10.1007/s12070-024-05001-2
Wei Jie Boon, Leong Wai Yee, Foong Seong Kin, Ing Ping Tang, Nur Shazwaniza Awang Basry, Boon Han Kevin Ng

Ceruminous adenoma is a rare and benign tumor of the external auditory canal and present with a nonspecific symptom. Biopsy with histopathology examination is required to establish the diagnosis. Wide local excision of tumour shows favourable outcome with a low recurrence rate. Here, we present a case of ceruminous adenoma masquerading as a furunculosis.

耵聍腺瘤是一种罕见的外耳道良性肿瘤,表现为非特异性症状。要确定诊断,必须进行活组织病理学检查。肿瘤局部广泛切除术效果良好,复发率低。在此,我们介绍一例伪装成疖肿的耵聍腺瘤。
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引用次数: 0
To Study the Microbiological Florae in Patients of Acute Otitis Externa. 研究急性外耳道炎患者的微生物菌群。
IF 0.6 Q4 SURGERY Pub Date : 2024-12-01 Epub Date: 2024-09-10 DOI: 10.1007/s12070-024-05058-z
Vijay Kalra, Sudeep Sharma, Nidhi Goel, Monika Khokhar, Aditya Bhargava, Parul Garg, Nitin Jindal, Naveen

Aim: To identify and know the antimicrobial sensitivities of the aerobic bacteria in patients with acute otitis externa (AOE).

Materials and methods: Sixty-six patients of acute otitis externa were prospectively analysed at a tertiary care centre in North-India from May 2021 to April 2022. Samples for culture and sensitivity were sent to the microbiology department and the results analysed.

Results: A total of 50 samples yielded positive results for bacterial cultures. The gram-negative isolates were 60%, and the gram-positive were 40%. Pseudomonas aeruginosa was the most common organism isolated overall (48%), followed by Staphylococcus aureus (36%). Pseudomonas aeruginosa isolates were found to be most susceptible to piperacillin + tazobactam and imipenem (100%), followed by cefepime (91.67%) and ciprofloxacin (87.5%) while the Staphylococcus aureus isolates were found to be most susceptible to linezolid (100%) and doxycycline (94.44%), followed by clindamycin (88.89%).

Conclusion: Causes of bacterial diversity and their varied anti-microbial sensitivities and increasing antimicrobial resistance due to inadvertent use of antibiotics over time has caused change in susceptibility of bacteria. It therefore becomes essential to periodically assess the microbiological flora so as to provide quality and cost-effective treatment to the patient population presenting with AOE.

目的:识别并了解急性外耳道炎(AOE)患者需氧菌的抗菌敏感性:2021 年 5 月至 2022 年 4 月,印度北部一家三级医疗中心对 66 例急性外耳道炎患者进行了前瞻性分析。样本送至微生物部门进行培养和药敏试验,并对结果进行分析:结果:共有 50 份样本的细菌培养结果呈阳性。革兰氏阴性分离菌占 60%,革兰氏阳性分离菌占 40%。铜绿假单胞菌是最常见的分离菌(48%),其次是金黄色葡萄球菌(36%)。铜绿假单胞菌对哌拉西林+他唑巴坦和亚胺培南最敏感(100%),其次是头孢吡肟(91.67%)和环丙沙星(87.5%),而金黄色葡萄球菌对利奈唑胺(100%)和强力霉素(94.44%)最敏感,其次是林可霉素(88.89%):细菌多样性的原因及其不同的抗微生物敏感性,以及由于长期不慎使用抗生素而导致的抗微生物耐药性的增加,造成了细菌敏感性的变化。因此,必须定期评估微生物菌群,以便为出现 AOE 的患者提供优质、经济的治疗。
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引用次数: 0
Clinical and Sociodemographic Predictors of Parental Perceptions and Confidence in Managing Child Stuttering: a Cross-Sectional Study. 家长对管理儿童口吃的看法和信心的临床和社会人口预测因素:一项横断面研究。
IF 0.6 Q4 SURGERY Pub Date : 2024-12-01 Epub Date: 2024-08-24 DOI: 10.1007/s12070-024-04998-w
Ebrahim Barzegar Bafrooei, Morteza Farazi, Saman Maroufizadeh, Akbar Darouie

The main aim of the current study was to identify and analyze the most significant clinical and sociodemographic predictors of parents' perceptions regarding their child's stuttering. 139 parents, with at least one child who stutters, completed both the Persian version of the Palin Parent Rating Scale (P-Palin PRS) and a sociodemographic and clinical checklist. To investigate the relationships between scores on the Palin PRS factors and sociodemographic and clinical characteristics, we conducted univariable analyses using Pearson correlation coefficients, independent t-tests, and one-way ANOVA. The study analyzed the P-Palin PRS factors: Impact of Stuttering on the Child, Severity of Stuttering and Impact on the Parents, and Parent's Knowledge and Confidence in Managing it. Mean scores were 5.37, 3.87, and 5.42, respectively, with correlations ranging from 0.371 to 0.507. Higher stutter severity negatively correlated with Impact on the Child (r=-0.364, P < 0.001). History of speech therapy (ST) failure and family history of speech and language disorders (SLDs) showed lower Impact scores (P = 0.053 and P = 0.057). Severity of Stuttering and Impact on the Parents negatively correlated with stutter severity (r=-0.546, P < 0.001) and positively with parents' ages. Parent's Knowledge and Confidence correlated negatively with stutter severity (r=-0.242, P = 0.004) and was lower in those with family history of SLDs (P = 0.008). The high stutter severity, ST failure, and family history of SLDs were associated with lower scores across all PRS factors. In conclusion current study identified key predictors influencing parents' perceptions of their child's stuttering, including stutter severity, speech therapy history, and family background.

本研究的主要目的是找出并分析父母对其子女口吃看法的最重要临床和社会人口预测因素。139 名至少有一名孩子口吃的家长填写了波斯语版的佩林家长评分量表(P-Palin PRS)以及一份社会人口和临床检查表。为了研究帕林 PRS 各因子得分与社会人口学和临床特征之间的关系,我们使用皮尔逊相关系数、独立 t 检验和单因素方差分析进行了单变量分析。研究分析了 P-Palin PRS 因子:口吃对儿童的影响、口吃的严重程度和对父母的影响、父母对处理口吃的知识和信心。平均得分分别为 5.37、3.87 和 5.42,相关系数为 0.371 至 0.507。较高的口吃严重程度与对儿童的影响呈负相关(r=-0.364,P = 0.053 和 P = 0.057)。口吃严重程度和对父母的影响与口吃严重程度呈负相关(r=-0.546,P r=-0.242,P = 0.004),有 SLD 家族史者的口吃严重程度较低(P = 0.008)。口吃严重程度高、ST失败和SLD家族史与所有PRS因素的得分较低有关。总之,本研究确定了影响家长对子女口吃看法的主要预测因素,包括口吃严重程度、言语治疗史和家庭背景。
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引用次数: 0
Acoustics Features of Cervical Auscultation in Dysphagic and Dysphonic Individuals: A Preliminary Study. 发音障碍和失音患者颈部听诊的声学特征:初步研究
IF 0.6 Q4 SURGERY Pub Date : 2024-12-01 Epub Date: 2024-09-11 DOI: 10.1007/s12070-024-05035-6
Syam Krishna Vijayan, Krishna Yeshoda

The acoustics of cervical auscultation of swallowing, a potential objective tool for the swallowing assessment, has been explored in normal subjects. However, there needs to be more literature profiling the same in individuals with swallowing problems. The study estimated the acoustic features of swallowing sounds in individuals with swallowing and voice problems and compared them with the previous reported findings in literature. Eight individuals with dysphonia and dysphagia were recruited to analyse cervical auscultation using a vibration pickup conduction microphone attached to the cricoid region on the neck of each participant. The participants showed different acoustic wave morphologies for swallowing sounds, including multiple waves, which were absent in the normal waveforms. The mean intensity, peak intensity were as higher in the current study participants than normal values reported literature in previous, suggesting increased strain and effort in individuals with dysphagia. The duration parameters were comparatively longer than those reported in previous literature showing the prolonged pharyngeal stage. The morphological and acoustic characteristics of swallow sounds in dysphagic and dysphonic individuals are deviating from then normal patterns. The utilisation of these features will help comprehensive diagnosis of swallowing difficulties. The LTAS was found to be the appropriate way of estimating the frequency of the peak intensity than using the intensity contour in the spectrogram since the values calculated using LTAS are more representative of the parameters. The study was a preliminary attempt to explore the acoustic features in individuals with voice and swallowing problems.

颈椎听诊的吞咽声学是一种潜在的客观吞咽评估工具,已在正常人身上进行了探索。然而,还需要更多文献对有吞咽困难的人进行同样的分析。本研究估计了有吞咽和发声问题的人的吞咽声特征,并将其与之前文献报道的结果进行了比较。研究人员招募了八名患有发音障碍和吞咽困难的患者,使用安装在每位患者颈部环状区的振动拾取传导麦克风对颈部听诊进行分析。受试者的吞咽声显示出不同的声波形态,包括正常波形中不存在的多重波。本次研究参与者的平均强度和峰值强度均高于以往文献报道的正常值,这表明吞咽困难患者的应变和努力程度有所增加。持续时间参数比以往文献报道的参数要长,表明咽部阶段延长。吞咽困难和吞咽障碍患者吞咽音的形态和声学特征与正常模式存在偏差。利用这些特征将有助于吞咽困难的综合诊断。与使用频谱图中的强度等高线相比,LTAS 被认为是估计峰值强度频率的合适方法,因为使用 LTAS 计算出的值更能代表参数。这项研究是探索语音和吞咽困难患者声学特征的初步尝试。
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引用次数: 0
Enhancing Tonsillectomy Recovery with AI: A Comparative Study on Postoperative Care Outcomes. 用人工智能促进扁桃体切除术的恢复:术后护理效果比较研究
IF 0.6 Q4 SURGERY Pub Date : 2024-12-01 Epub Date: 2024-09-25 DOI: 10.1007/s12070-024-05103-x
Sanjay Kumar, Anghusman Dutta, Manish Gupta, Ran Singh

Introduction: Tonsillectomy is commonly associated with significant postoperative challenges such as pain management, complication monitoring, and patient recovery. Traditional care methods, while effective, often do not adequately address these issues, particularly in personalized care and remote monitoring. This study assesses the impact of Artificial Intelligence (AI)-assisted postoperative care on recovery outcomes in tonsillectomy patients compared to conventional care methods. Methods: Conducted at a tertiary care hospital's Otolaryngology Department from January to December 2023, this observational cohort study involved 100 elective tonsillectomy patients. Participants were divided into two cohorts: one receiving traditional care and the other AI-assisted care, which utilized machine learning for pain management, continuous symptom monitoring through wearable devices, and virtual assistance. Results: AI-assisted care significantly improved early postoperative pain management, reducing pain scores to 5.2 ± 1.1 from 6.5 ± 1.2 in traditional care (p = 0.01). Dehydration rates decreased from 6 to 1% (p = 0.05), and the average hospital stay was reduced to 2.8 ± 1.1 days from 3.5 ± 1.2 days. While no significant differences were found in readmission rates for haemorrhage and infection, patient satisfaction notably increased, with pain management improving to 4.4 ± 0.7 and overall satisfaction to 4.1 ± 0.6 (p = 0.03). Conclusion: AI-assisted care offers significant advantages over traditional methods in managing tonsillectomy recovery, optimizing surgical outcomes, and enhancing patient satisfaction. This study supports further exploration into AI's long-term outcomes and its application across various surgical fields.

Supplementary information: The online version contains supplementary material available at 10.1007/s12070-024-05103-x.

介绍:扁桃体切除术通常伴随着疼痛管理、并发症监测和患者恢复等重大术后挑战。传统的护理方法虽然有效,但往往不能充分解决这些问题,尤其是在个性化护理和远程监控方面。本研究评估了与传统护理方法相比,人工智能(AI)辅助术后护理对扁桃体切除术患者恢复效果的影响。研究方法这项观察性队列研究于 2023 年 1 月至 12 月在一家三级医院的耳鼻喉科进行,涉及 100 名扁桃体切除术择期患者。参与者被分为两组:一组接受传统护理,另一组接受人工智能辅助护理,后者利用机器学习进行疼痛管理,通过可穿戴设备持续监测症状,并提供虚拟协助。研究结果人工智能辅助护理显著改善了术后早期疼痛管理,将疼痛评分从传统护理的 6.5 ± 1.2 降至 5.2 ± 1.1(p = 0.01)。脱水率从 6% 降至 1%(p = 0.05),平均住院日从 3.5 ± 1.2 天降至 2.8 ± 1.1 天。虽然在大出血和感染的再入院率方面没有发现明显差异,但患者的满意度明显提高,疼痛管理满意度提高到 4.4 ± 0.7,总体满意度提高到 4.1 ± 0.6(p = 0.03)。结论与传统方法相比,人工智能辅助护理在管理扁桃体切除术恢复、优化手术效果和提高患者满意度方面具有显著优势。本研究支持进一步探索人工智能的长期效果及其在各外科领域的应用:在线版本包含补充材料,可在 10.1007/s12070-024-05103-x.获取。
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引用次数: 0
Speech Sound Disorders in Arabic School aged Children with Adenoid Hypertrophy. 患有腺样体肥大症的阿拉伯学龄儿童的语音障碍
IF 0.6 Q4 SURGERY Pub Date : 2024-12-01 Epub Date: 2024-08-13 DOI: 10.1007/s12070-024-04942-y
Hanan A Mohamed, Reham A Ibrahem

Background: Adenoid hypertrophy alters the posture of the oro-facial structures by obstructing the upper airways and restricting nasal breathing. These postural changes may eventually have an impact on facial skeletal development and dental occlusion. The postural adjustments may negatively impact a child's life by affecting a number of speech-production factors.

Objective: This study aimed to detect the speech sound disorders in school aged Egyptian children with adenoid hypertrophy and if they were related to structure changes in the airway that caused by adenoid hypertrophy.

Methodology: 300 school-aged Egyptian children aged from (5-15) years old with speech sound disorders (SSD). They were divided into 2 groups; Group 1 consisted of 150 children with speech (SSD) and adenoid hypertrophy, and Group 2 consisted of 150 children complained from (SSD) without adenoid hypertrophy. All children were evaluated by protocol of language assessment and articulation test used in Assiut University Hospital.

Results: Speech sound disorders (SSD) mainly the omission and distortion are more frequent in (group 2) while, the substitution errors are more prominent in (group 1). The interdental sigmatism was the most frequent speech sound disorder in (group 1) especially those with adenoid hypertrophy occupying more than 50% of the airway, whereas, devoicing, gliding and back to front are more frequent in (group 2).

Conclusion: Adenoid hypertrophy can affects only the /s/ sound production which needs precise placements of the articulators especially the tongue, and seems to be vulnerable due to the structural alteration of the oral cavity caused by adenoid hypertrophy.

背景:腺样体肥大会阻塞上呼吸道,限制鼻腔呼吸,从而改变口面部结构的姿势。这些姿势变化最终会影响面部骨骼发育和牙齿咬合。体位调整可能会影响到一些语言生成因素,从而对儿童的生活产生负面影响:本研究旨在检测患有腺样体肥大的埃及学龄儿童的语言发音障碍,以及这些障碍是否与腺样体肥大导致的气道结构变化有关。他们被分为两组:第一组包括 150 名患有语言障碍(SSD)和腺样体肥大的儿童,第二组包括 150 名患有语言障碍(SSD)但没有腺样体肥大的儿童。所有儿童都接受了阿苏特大学医院使用的语言评估和发音测试方案的评估:结果:语音障碍(SSD)主要是遗漏和失真在(第 2 组)中更为常见,而替换错误在(第 1 组)中更为突出。在(第 1 组)患者中,齿间嘶哑是最常见的语音障碍,尤其是腺样体肥大占据气道 50%以上的患者;而在(第 2 组)患者中,脱音、滑音和从前向后脱音更为常见:结论:腺样体肥大只影响 /s/ 的发音,该发音需要发音器官(尤其是舌头)的精确定位,而且似乎容易受到腺样体肥大导致的口腔结构改变的影响。
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引用次数: 0
Salivary pH testing in Laryngopharyngeal Reflux Disease. 喉咽反流病的唾液 pH 值检测
IF 0.6 Q4 SURGERY Pub Date : 2024-12-01 Epub Date: 2024-10-05 DOI: 10.1007/s12070-024-05109-5
Chethana R, Amruta Chutke, Rohit Jadhav, Siddharth Ramanathan, Shamli Shamkant

To determine salivary pH in patients with Laryngopharyngeal Reflux (LPR) and compare it with that of normal individuals. A cross sectional analytical study was done. Adults with LPR as determined by Reflux Symptom Index (RSI) > 13 and Reflux Finding Score (RFS) > 7 were included in LPR group. Normal healthy adult participants with Reflux Symptom Index ≤ 3 and Reflux Finding Score ≤ 2 were included in non LPR group.32 participants were included in each groups. Salivary pH was determined in all participants using a standardized pH meter. Difference in salivary pH between two groups was statistically analyzed. The mean salivary pH in LPR group was 7.43 ± 0.77 and in non LPR group 7.0 ± 0.77. There was a statistically significant difference between the mean salivary pH between the two groups as determined by p value 0.004. The results of our exploratory study showed statistically significant difference in salivary pH between LPR and non LPR group. The salivary pH in 10(31.2%) out of 32 participants in LPR group was beyond the normal range and surprisingly the value was > 7.6, which was in contrast to acidic pH that was expected as per hypothesis. The rest 68.8% in LPR group had pH in the normal range. However salivary pH as a modality for diagnosing LPR cannot be concluded from such preliminary study with a small study population. This study forms a basis for future research for the role of salivary pH in LPR with better study designs and finer modalities of pH testing.

测定喉咽反流(LPR)患者的唾液 pH 值,并与正常人的唾液 pH 值进行比较。我们进行了一项横断面分析研究。根据反流症状指数 (RSI) > 13 和反流发现评分 (RFS) > 7 确定的 LPR 成人被纳入 LPR 组。反流症状指数小于 3 和反流发现评分小于 2 的正常健康成人被纳入非 LPR 组。所有参与者均使用标准 pH 计测定唾液 pH 值。对两组之间唾液 pH 值的差异进行统计分析。LPR 组的平均唾液 pH 值为 7.43 ± 0.77,非 LPR 组为 7.0 ± 0.77。根据 P 值 0.004 的测定,两组之间唾液 pH 值的平均值存在明显的统计学差异。我们的探索性研究结果表明,LPR 组和非 LPR 组的唾液 pH 值差异具有统计学意义。在 LPR 组的 32 名参与者中,有 10 人(31.2%)的唾液 pH 值超出了正常范围,而且竟然大于 7.6,这与假设的酸性 pH 值形成了鲜明对比。LPR 组中其余 68.8% 的人 pH 值在正常范围内。然而,唾液 pH 值作为诊断 LPR 的一种方式,还不能从这项针对少数研究人群的初步研究中得出结论。本研究为今后研究唾液 pH 值在 LPR 中的作用奠定了基础,研究设计更完善,pH 值测试方法更精细。
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引用次数: 0
Speech and Language Development 5 Years Post-Implantation:- The Value of Continuity of Auditory Verbal Therapy. 植入后 5 年的言语和语言发展:听觉言语疗法持续性的价值。
IF 0.6 Q4 SURGERY Pub Date : 2024-12-01 Epub Date: 2024-08-13 DOI: 10.1007/s12070-024-04983-3
Ravi Shankar Kumar, Vanita Sarin, Noorain Alam

Cochlear implants (CIs) are a well-established treatment for severe to profound hearing loss, particularly in young children. The success of CIs is influenced by various factors, including the age of implantation and the quality and duration of post-operative rehabilitation, such as Auditory Verbal Therapy (AVT). AVT plays a crucial role in developing listening and spoken language skills in children with CIs. However, the impact of AVT duration on long-term outcomes remains unclear. This study aimed to investigate the impact of AVT duration on the long-term auditory and speech outcomes of children who received CIs between 9 and 12 months of age. Specifically, we compared the outcomes of children who received AVT for one year, one and a half years, and two years after implantation. This descriptive cohort study included 45 children diagnosed with severe to profound hearing loss who received unilateral CIs and completed at least one year of AVT. Participants were divided into three groups based on AVT duration (Group A: 1 year, Group B: 1.5 years, Group C: 2 years). Their auditory perception, speech intelligibility, receptive and expressive language, and speech production skills were assessed using standardized tests five years post-implantation.. Children who received AVT for two years (Group C) demonstrated significantly better outcomes in auditory perception and speech intelligibility compared to those who received AVT for one year (Group A). Group C also exhibited higher scores in expressive language and speech production, while both groups achieved similar results in receptive language. These findings suggest a positive correlation between AVT duration and long-term language and speech development. Early cochlear implantation, coupled with continuous AVT for at least two years, significantly enhances auditory and speech abilities in children with severe to profound hearing loss. This study underscores the importance of extended AVT duration to maximize the long-term benefits of cochlear implants and enable children to reach their full communication potential.

人工耳蜗(CI)是治疗重度到极重度听力损失的一种行之有效的方法,尤其适用于幼儿。人工耳蜗的成功与否受多种因素的影响,包括植入年龄、术后康复的质量和持续时间,如听觉言语治疗(AVT)。听觉言语治疗在培养植入人工耳蜗儿童的听力和口语技能方面起着至关重要的作用。然而,听觉言语治疗持续时间对长期疗效的影响仍不清楚。本研究旨在调查 AVT 持续时间对 9 到 12 个月大接受 CI 的儿童的长期听力和言语效果的影响。具体来说,我们比较了植入后一年、一年半和两年内接受 AVT 的儿童的疗效。这项描述性队列研究包括 45 名被诊断为重度至极重度听力损失的儿童,他们接受了单侧 CI 并完成了至少一年的 AVT。根据 AVT 的持续时间将参与者分为三组(A 组:1 年;B 组:1.5 年;C 组:2 年)。他们的听觉感知、言语理解能力、接受性和表达性语言以及言语表达能力在植入后五年通过标准化测试进行评估。与接受 AVT 治疗一年的儿童(A 组)相比,接受 AVT 治疗两年的儿童(C 组)在听觉感知和言语清晰度方面的表现明显更好。C 组儿童在语言表达和言语生成方面的得分也更高,而两组儿童在接受性语言方面的成绩相近。这些研究结果表明,AVT 的持续时间与长期语言和言语发展之间存在正相关关系。早期人工耳蜗植入加上至少两年的持续 AVT,可显著提高重度至极重度听力损失儿童的听觉和言语能力。这项研究强调了延长 AVT 持续时间的重要性,以最大限度地发挥人工耳蜗植入的长期效益,使儿童能够充分发挥其沟通潜能。
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引用次数: 0
Use of Autologous Leukocyte-Platelet Rich Fibrin (L-PRF) in Endoscopic Anterior Skull Base Defect Repair-A Newer Graft Material: Name of Authors. 自体白细胞-血小板丰富纤维蛋白(L-PRF)在内窥镜颅底前部缺损修复中的应用--一种较新的移植物材料:作者姓名.
IF 0.6 Q4 SURGERY Pub Date : 2024-12-01 Epub Date: 2024-09-17 DOI: 10.1007/s12070-024-05046-3
Ramraj Yadav, Ashvanee Kumar Chaudhary, Deepak Kumar Gupta, Sanjay Kumar Saroj, Vishwambhar Singh, Rajesh Kumar

CSF rhinorrhea secondary to anterior skull base defect may be spontaneous or traumatic (accidental or iatrogenic), spontaneous being common in middle aged, obese females. Nowadays endoscopic technique is gold standard for anterior skull base defect repair. The graft materials available may be autologous (fat, temporalis fascia, fascia lata, septal mucosa, cartilage, middle turbinate), homologous e.g., cadaveric pericardium or allograft e.g. dural substitute. Leukocyte-platelet rich fibrin (L-PRF) is a newer graft material that contain concentrated platelets and doesn't require any exogenous material or chemical in blood. A prospective study including 31 patients was carried out at tertiary care centre in eastern India, over the period of 2 years. All the surgeries targeted for closure of the anterior skull base defect were performed endoscopically under general anaesthesia. 30 out of 31 (96.77%) patients successfully improved after repair and one patient required revision surgery due to recurrence of disease and was cured after revision surgery. Autologous Leokocyte-plasma rich fibrin (L-PRF) is a newer and cost-effective graft material for the CSF leak repair with good healing property and with a success rate of more than 95%.

继发于前颅底缺损的 CSF 鼻溢液可能是自发性的,也可能是外伤性的(意外或先天性),自发性鼻溢液常见于中年肥胖女性。如今,内窥镜技术已成为修复前颅底缺损的金标准。移植材料可以是自体(脂肪、颞筋膜、筋膜、鼻中隔粘膜、软骨、中鼻甲)、同源(如尸体心包)或异体(如硬脑膜替代物)。富含白细胞-血小板的纤维蛋白(L-PRF)是一种较新的移植材料,它含有浓缩血小板,不需要任何外源性材料或血液中的化学物质。一项前瞻性研究在印度东部的三级医疗中心进行,共纳入 31 名患者,为期两年。所有用于闭合前颅底缺损的手术都是在全身麻醉的情况下通过内窥镜进行的。31 名患者中有 30 名(96.77%)在修复手术后病情成功好转,一名患者因病情复发而需要进行翻修手术,在翻修手术后痊愈。自体富含 Leokocyte 血浆纤维蛋白(L-PRF)是一种较新且经济有效的 CSF 漏修复移植材料,具有良好的愈合性能,成功率超过 95%。
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Indian Journal of Otolaryngology and Head and Neck Surgery
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