Background: The prevalence of suicide is increasing worldwide and nowadays approximately one million people commit suicide every year. In Slovenia, suicide is a major public health and social problem. Suicide rate in Slovenia is among the highest in Europe. Despite intensive research work on suicide in the countries with high suicide rates and despite all new data on risk factors, the suicide rates do not decline (with few exceptions). Nevertheless, suicide prevention is possible if it is based on research data and included in the National programme of suicide prevention. Conclusions: Slovenia being highly endangered by suicide, its Gorvernment should immediately nominate a working group which would prepare a National programme of suicide prevention.
{"title":"Suicidal behaviour in Slovenia","authors":"S. Ziherl, P. Pregelj","doi":"10.6016/318","DOIUrl":"https://doi.org/10.6016/318","url":null,"abstract":"Background: The prevalence of suicide is increasing\u0000worldwide and nowadays approximately\u0000one million people commit suicide every year.\u0000In Slovenia, suicide is a major public health and\u0000social problem. Suicide rate in Slovenia is among\u0000the highest in Europe. Despite intensive research\u0000work on suicide in the countries with high suicide\u0000rates and despite all new data on risk factors,\u0000the suicide rates do not decline (with few exceptions).\u0000Nevertheless, suicide prevention is possible\u0000if it is based on research data and included in\u0000the National programme of suicide prevention.\u0000Conclusions: Slovenia being highly endangered\u0000by suicide, its Gorvernment should immediately\u0000nominate a working group which would prepare\u0000a National programme of suicide prevention.","PeriodicalId":49350,"journal":{"name":"Zdravniski Vestnik-Slovenian Medical Journal","volume":"540 1","pages":"559-562"},"PeriodicalIF":0.0,"publicationDate":"2010-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77987537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2010-05-01DOI: 10.1164/AJRCCM-CONFERENCE.2010.181.1_MEETINGABSTRACTS.A5996
M. Terčelj, B. Salobir, R. Rylander
{"title":"Anti-fungal medication and sarcoidosis.","authors":"M. Terčelj, B. Salobir, R. Rylander","doi":"10.1164/AJRCCM-CONFERENCE.2010.181.1_MEETINGABSTRACTS.A5996","DOIUrl":"https://doi.org/10.1164/AJRCCM-CONFERENCE.2010.181.1_MEETINGABSTRACTS.A5996","url":null,"abstract":"","PeriodicalId":49350,"journal":{"name":"Zdravniski Vestnik-Slovenian Medical Journal","volume":"17 1","pages":"825-828"},"PeriodicalIF":0.0,"publicationDate":"2010-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83912787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Prophylactic antifungal treatments as well as an appropriate protective environment are essential for prevention of invasive fungal infections in the immunocompromised patients. h e aim of our study was to determine the species and concentrations of airborne moulds in various hospital indoor environments as well as the immediate outdoor environment. We have also tested three dif erent growth media in an attempt to establish which one is the most appropriate for air sampling. Methods: Between October 2007 and March 2008 air samples have been collected from two construction sites at UMC Ljubljana and the immediate outdoor environment with no construction works as well as in a regular hospital ward and an ICU of UMC Ljubljana. h e recovered moulds were then identified
{"title":"Species diversity and concentration of moulds in air samples from hospital indoor and outdoor environment","authors":"T. Matos, Tanja Kavčič","doi":"10.6016/266","DOIUrl":"https://doi.org/10.6016/266","url":null,"abstract":"Background: Prophylactic antifungal treatments as well as an appropriate protective \u0000environment are essential for prevention of \u0000invasive fungal infections in the immunocompromised patients. h e aim of our study \u0000was to determine the species and concentrations of airborne moulds in various hospital \u0000indoor environments as well as the immediate outdoor environment. We have also tested \u0000three dif erent growth media in an attempt to \u0000establish which one is the most appropriate \u0000for air sampling.\u0000Methods: Between October 2007 and March \u00002008 air samples have been collected from \u0000two construction sites at UMC Ljubljana and \u0000the immediate outdoor environment with \u0000no construction works as well as in a regular \u0000hospital ward and an ICU of UMC Ljubljana. \u0000h e recovered moulds were then identified","PeriodicalId":49350,"journal":{"name":"Zdravniski Vestnik-Slovenian Medical Journal","volume":"13 1","pages":"117-126"},"PeriodicalIF":0.0,"publicationDate":"2010-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75550123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background:The purpose of this study was the possibility to follow the progress of labour using electromyographic (EMG) signals obtained from the uterine corpus and the cervix. Methods: 28 healty primiparous women with induced labour at an age from 19 to 29 years were enrolled in the study. For interpretation of EMG signals Sample entropy (SampEn), the measure of time series regularity was used. SampEn values were related to the progress of labour recorded in the partogram. h e main outcome is association between labour progress and values of SampEn. Results: Approaching the childbirth during normally progressing labour, regular activity of uterine corpus muscles and cervical muscles is indicated as a decreasing trend in values of SampEn. A delay in the active phase of labour due to active contractions of cervical circular muscles is indicated in greater values of SampEn calculated from cervical EMG activity. Conclusions: By measuring and processing of EMG signals from the uterine corpus and the cervix an obstetrician can obtain an additional useful information on the progress of labour.
{"title":"A uterine electromyographic activity as a measure of labour progression","authors":"J. Vrhovec, D. Rudel, M. Pajntar, A. M. Lebar","doi":"10.5772/25526","DOIUrl":"https://doi.org/10.5772/25526","url":null,"abstract":"Background:The purpose of this study was \u0000the possibility to follow the progress of labour \u0000using electromyographic (EMG) signals obtained from the uterine corpus and the cervix.\u0000Methods: 28 healty primiparous women \u0000with induced labour at an age from 19 to \u000029 years were enrolled in the study. For interpretation of EMG signals Sample entropy \u0000(SampEn), the measure of time series regularity was used. SampEn values were related \u0000to the progress of labour recorded in the partogram. h e main outcome is association between labour progress and values of SampEn.\u0000Results: Approaching the childbirth during \u0000normally progressing labour, regular activity of uterine corpus muscles and cervical \u0000muscles is indicated as a decreasing trend in \u0000values of SampEn. A delay in the active phase \u0000of labour due to active contractions of cervical circular muscles is indicated in greater \u0000values of SampEn calculated from cervical \u0000EMG activity.\u0000Conclusions: By measuring and processing \u0000of EMG signals from the uterine corpus and \u0000the cervix an obstetrician can obtain an additional useful information on the progress \u0000of labour.","PeriodicalId":49350,"journal":{"name":"Zdravniski Vestnik-Slovenian Medical Journal","volume":"2004 1","pages":"109-116"},"PeriodicalIF":0.0,"publicationDate":"2010-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86237370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
As syphilis incidence has been declining over the past few decades, a general belief is present that it has become practically eradicated. But since the 1990s reports about local outbreaks, mostly related to men who have sex with men (MSM), have been published. In the past two years we have seen seven cases of syphilis in our proctology units that have been overlooked by other physicians. In this article a few interesting cases are presented. Not only the risk groups, but physicians as well need to be informed about the increasing incidence of syphilis. When a patient is diagnosed with a sexually transmited infection (STI) or there is a clinical suspicion that he might have one, a screening test for the most common STIs should be performed which should also include testing for syphilis.
{"title":"Missed Cases of Syphilis","authors":"V. H. Topčič, B. Mlakar","doi":"10.6016/439","DOIUrl":"https://doi.org/10.6016/439","url":null,"abstract":"As syphilis incidence has been declining over\u0000the past few decades, a general belief is present\u0000that it has become practically eradicated.\u0000But since the 1990s reports about local\u0000outbreaks, mostly related to men who have\u0000sex with men (MSM), have been published.\u0000In the past two years we have seen seven cases\u0000of syphilis in our proctology units that have\u0000been overlooked by other physicians. In this\u0000article a few interesting cases are presented.\u0000Not only the risk groups, but physicians as\u0000well need to be informed about the increasing\u0000incidence of syphilis. When a patient\u0000is diagnosed with a sexually transmited infection\u0000(STI) or there is a clinical suspicion\u0000that he might have one, a screening test for\u0000the most common STIs should be performed\u0000which should also include testing for syphilis.","PeriodicalId":49350,"journal":{"name":"Zdravniski Vestnik-Slovenian Medical Journal","volume":"80 1","pages":"777-781"},"PeriodicalIF":0.0,"publicationDate":"2009-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84217148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiopulmonary resuscitation in the prehospital setting still has to cope with poor lay-rescuer knowledge of resuscitation techniques, low public availability of automated external defi brillators, many detrimental interruptions of chest compressions during lay and professional resuscitation eff orts and suboptimal postresuscitation care. Th erefore the survival of patients aft er cardiac arrest remains poor. To address those fl aws, cardiopulmonary resuscitation guidelines of 2005 are targeted at improving cardiopulmonary resuscitation by achieving adequate depth, number, and minimal interruptions of chest compressions per minute, and avoiding hyperventilation. But a combination of chest compressions and rescue breathing is still the mainstay of resuscitation ofi n primary and secondary cardiac arrest despite diff erent pathophysiological causes. In the last two decades a concept of cardiocerebral resuscitation emerged, and according to research it is equal to or even better than standard cardiopulmonary resuscitation in terms of patients' prognosis aft er successful resuscitation of sudden or primary unexpected cardiac arrest. Cardiocerebral resuscitation of patients with primary cardiac arrest consists of layrescuer uninterrupted chest compressions without rescue breathing in the fi rst minutes of resuscitation, advanced life support techniques that do not interrupt chest compressions and thus maintain their positive hemodynamic eff ects. If professional rescuers arrive at the scene within 4 to 5 minutes aft er primary cardiac arrest, defi brillation should be attempted prior to resuscitation techiques, but if professional help arrives later than 4 to 5 minutes aft er primary cardiac arrest, two minutes of resuscitation techniques should be performed prior to the fi rst defi brillation. Post-resuscitation care includes mild induced hypothermia, coronarography and percutaneous coronary intervention.
{"title":"Cardiocerebral resuscitation: facts and prospects","authors":"D. Kupnik, M. Krizmaric","doi":"10.6016/436","DOIUrl":"https://doi.org/10.6016/436","url":null,"abstract":"Cardiopulmonary resuscitation in the prehospital\u0000setting still has to cope with poor\u0000lay-rescuer knowledge of resuscitation techniques,\u0000low public availability of automated\u0000external defi brillators, many detrimental\u0000interruptions of chest compressions during\u0000lay and professional resuscitation eff orts and\u0000suboptimal postresuscitation care. Th erefore\u0000the survival of patients aft er cardiac arrest\u0000remains poor. To address those fl aws, cardiopulmonary\u0000resuscitation guidelines of 2005\u0000are targeted at improving cardiopulmonary\u0000resuscitation by achieving adequate depth,\u0000number, and minimal interruptions of chest compressions per minute, and avoiding\u0000hyperventilation. But a combination of chest\u0000compressions and rescue breathing is still the\u0000mainstay of resuscitation ofi n primary and\u0000secondary cardiac arrest despite diff erent\u0000pathophysiological causes. In the last two\u0000decades a concept of cardiocerebral resuscitation\u0000emerged, and according to research it\u0000is equal to or even better than standard cardiopulmonary\u0000resuscitation in terms of patients'\u0000prognosis aft er successful resuscitation\u0000of sudden or primary unexpected cardiac arrest.\u0000Cardiocerebral resuscitation of patients\u0000with primary cardiac arrest consists of layrescuer\u0000uninterrupted chest compressions without rescue breathing in the fi rst minutes\u0000of resuscitation, advanced life support techniques\u0000that do not interrupt chest compressions\u0000and thus maintain their positive hemodynamic\u0000eff ects. If professional rescuers\u0000arrive at the scene within 4 to 5 minutes aft er\u0000primary cardiac arrest, defi brillation should\u0000be attempted prior to resuscitation techiques,\u0000but if professional help arrives later than 4 to\u00005 minutes aft er primary cardiac arrest, two\u0000minutes of resuscitation techniques should\u0000be performed prior to the fi rst defi brillation.\u0000Post-resuscitation care includes mild induced\u0000hypothermia, coronarography and percutaneous\u0000coronary intervention.","PeriodicalId":49350,"journal":{"name":"Zdravniski Vestnik-Slovenian Medical Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2009-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90438313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mobile phones are ubiquitous among several groups of population, representing an important social factor by providing the connectivity between an individual and a distant or close environment. During the decades of technological advances these devices have evolved from the basic voice-oriented gadgets to effi cient tools available on diff erent service areas. Combining custom designed soft ware, local wireless connectivity modules, motion sensors, location-estimation units and audio- visual interfaces they introduce innovative approaches to protection, preservation and improvement of health. Our Laboratory for Telecommunications is actively involved into research and development progress activities since the year 2000 with the results described in the following sections and integrated in several existing solutions under the Administration of the Republic of Slovenia for Civil Protection and Disaster Relief and Institute for Rehabilitation. Th e applications availability conforming to the »anytime anywhere« principle is enabled by mobile operators' networks global coverage. Due to this global effi ciency the list of remote services like telemedicine, awareness, education, prevention and protection suitable for patients and medical personnel is steadily growing. Signifi cant advantages are increased feelings of safety, time and cost savings, shortened waiting queues, improved quality of life and possibilities to develop additional health-related activities.
{"title":"Mobile phone as a tool in the areas of health protection","authors":"A. Štern, A. Kos","doi":"10.6016/430","DOIUrl":"https://doi.org/10.6016/430","url":null,"abstract":"Mobile phones are ubiquitous among several\u0000groups of population, representing an important\u0000social factor by providing the connectivity\u0000between an individual and a distant\u0000or close environment. During the decades of\u0000technological advances these devices have\u0000evolved from the basic voice-oriented gadgets\u0000to effi cient tools available on diff erent service\u0000areas. Combining custom designed soft ware,\u0000local wireless connectivity modules, motion\u0000sensors, location-estimation units and audio-\u0000visual interfaces they introduce innovative\u0000approaches to protection, preservation\u0000and improvement of health. Our Laboratory\u0000for Telecommunications is actively involved\u0000into research and development progress activities\u0000since the year 2000 with the results\u0000described in the following sections and integrated\u0000in several existing solutions under the\u0000Administration of the Republic of Slovenia\u0000for Civil Protection and Disaster Relief and\u0000Institute for Rehabilitation.\u0000Th e applications availability conforming to\u0000the »anytime anywhere« principle is enabled\u0000by mobile operators' networks global coverage. Due to this global effi ciency the list of\u0000remote services like telemedicine, awareness,\u0000education, prevention and protection suitable\u0000for patients and medical personnel is\u0000steadily growing. Signifi cant advantages are increased feelings of safety, time and cost savings,\u0000shortened waiting queues, improved\u0000quality of life and possibilities to develop additional\u0000health-related activities.","PeriodicalId":49350,"journal":{"name":"Zdravniski Vestnik-Slovenian Medical Journal","volume":"13 1","pages":"673-684"},"PeriodicalIF":0.0,"publicationDate":"2009-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75276014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-05-01DOI: 10.1016/S0378-5122(09)70069-6
K. Geršak, J. Cerne, P. Ferk, B. Leskosek
{"title":"The use of hormone replacement therapy in Slovenian women before the first diagnosis of breast cancer.","authors":"K. Geršak, J. Cerne, P. Ferk, B. Leskosek","doi":"10.1016/S0378-5122(09)70069-6","DOIUrl":"https://doi.org/10.1016/S0378-5122(09)70069-6","url":null,"abstract":"","PeriodicalId":49350,"journal":{"name":"Zdravniski Vestnik-Slovenian Medical Journal","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2009-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84063901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background Ethical dilemmas are an important part of daily routine in family practice. One of the options for better quality in family practice is also an effective postgraduate education in the field of bioethics. We wanted to determine the influence of the specialization process on the susceptibility of family physicians to ethical dilemmas and their solving difficulty. We hypothesized that specialists in family medicine would detect the ethical dilemmas more often and that they would report of less problems in their managing. Methods The cross-sectional study included a random sample of 259 Slovenian family medicine physicians (30 % of the whole population of family physicians). Participants were given a self-administered questionnaire on perceived ethical dilemmas in family practice with responses on a 5-point scale and a maximum score of 100. Results In the final analysis 142 Slovenian family medicine physicians (55 % response rate) were included. Specialists in family medicine and residents of family medicine reported ethical dilemmas more often than their colleagues without specialization (37.0 ± 12.6 vs. 30.7 ± 10.8; P = 0.05). Similarly, the residents of family medicine reported ethical dilemmas more often than their colleagues without specialization (39.5 ± 12.5 vs. 30.7 ± 10.8, P = 0.04). Specialists in family medicine and residents of family medicine considered solving ethical dilemmas to be more difficult than their colleagues without specialization (57.3 ± 11.6 vs. 47.1 ± 11.8, P = 0.001). The same differences exist also between the specialists in family medicine and their colleagues without specialization (56.7 ± 11.7 vs. 47.1 ± 11.8, P = 0.003) and between the residents of family medicine and their colleagues without specialization (62.0 ± 10.0 vs. 47.1 ± 11.8, P = 0.001). Conclusions Physicians that are working in family practices need effective postgraduate education in the field of detection and management of ethical dilemmas. The questionnaire for perceived ethical dilemmas proved to be a reliable instrument for evaluation of education’s effectiveness.
{"title":"INFLUENCE OF SPECIALISTIC TRAINING IN FAMILY MEDICINE ON DETECTION AND MANAGEMENT OF ETHICAL DILEMMAS","authors":"Z. Klemenc-Ketiš, Janja Ojstersek, J. Kersnik","doi":"10.6016/379","DOIUrl":"https://doi.org/10.6016/379","url":null,"abstract":"Background Ethical dilemmas are an important part of daily routine in family practice. One of the options for better quality in family practice is also an effective postgraduate education in the \u0000field of bioethics. We wanted to determine the influence of the specialization process on \u0000the susceptibility of family physicians to ethical dilemmas and their solving difficulty. We \u0000hypothesized that specialists in family medicine would detect the ethical dilemmas more \u0000often and that they would report of less problems in their managing.\u0000Methods The cross-sectional study included a random sample of 259 Slovenian family medicine \u0000physicians (30 % of the whole population of family physicians). Participants were given \u0000a self-administered questionnaire on perceived ethical dilemmas in family practice with \u0000responses on a 5-point scale and a maximum score of 100.\u0000Results In the final analysis 142 Slovenian family medicine physicians (55 % response rate) were \u0000included. Specialists in family medicine and residents of family medicine reported ethical \u0000dilemmas more often than their colleagues without specialization (37.0 ± 12.6 vs. 30.7 ± \u000010.8; P = 0.05). Similarly, the residents of family medicine reported ethical dilemmas more \u0000often than their colleagues without specialization (39.5 ± 12.5 vs. 30.7 ± 10.8, P = 0.04). \u0000Specialists in family medicine and residents of family medicine considered solving ethical \u0000dilemmas to be more difficult than their colleagues without specialization (57.3 ± 11.6 vs. \u000047.1 ± 11.8, P = 0.001). The same differences exist also between the specialists in family \u0000medicine and their colleagues without specialization (56.7 ± 11.7 vs. 47.1 ± 11.8, P = 0.003) \u0000and between the residents of family medicine and their colleagues without specialization \u0000(62.0 ± 10.0 vs. 47.1 ± 11.8, P = 0.001).\u0000Conclusions Physicians that are working in family practices need effective postgraduate education in \u0000the field of detection and management of ethical dilemmas. The questionnaire for perceived \u0000ethical dilemmas proved to be a reliable instrument for evaluation of education’s effectiveness.","PeriodicalId":49350,"journal":{"name":"Zdravniski Vestnik-Slovenian Medical Journal","volume":"17 1","pages":"169-174"},"PeriodicalIF":0.0,"publicationDate":"2009-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73995425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background The rapid development of genetics has brought an increasing knowledge of the molecular bases of diseases, which in turn has allowed for the development of accurate diagnostic test – DNA analysis. The goal of DNA analysis in medicine is to detect genetic changes which by molecular logic is the most accurate way to confirm the presence of genetic disease. Conclusions In the article we try to highlight the complexity of the use of genetic testing, as, besides the importance of indicating the appropriate analysis, correct interpretation of any results, an understanding of the limits of testing and its specificity, there are many legal and ethical implications connected with genetic testing. It therefore follows that genetic counseling should be an integral part of the process of genetic testing. At the end of the article we describe the organization of genetic testing in Slovenia and try to give some recommendations regarding the use of genetic testing in clinical medicine.
{"title":"Practical considerations of DNA testing in medicine.","authors":"G. Rudolf, B. Peterlin","doi":"10.6016/369","DOIUrl":"https://doi.org/10.6016/369","url":null,"abstract":"Background The rapid development of genetics has brought an increasing knowledge of the molecular\u0000bases of diseases, which in turn has allowed for the development of accurate diagnostic test\u0000– DNA analysis. The goal of DNA analysis in medicine is to detect genetic changes which by\u0000molecular logic is the most accurate way to confirm the presence of genetic disease.\u0000Conclusions In the article we try to highlight the complexity of the use of genetic testing, as, besides the\u0000importance of indicating the appropriate analysis, correct interpretation of any results, an\u0000understanding of the limits of testing and its specificity, there are many legal and ethical\u0000implications connected with genetic testing. It therefore follows that genetic counseling\u0000should be an integral part of the process of genetic testing.\u0000At the end of the article we describe the organization of genetic testing in Slovenia and try\u0000to give some recommendations regarding the use of genetic testing in clinical medicine.","PeriodicalId":49350,"journal":{"name":"Zdravniski Vestnik-Slovenian Medical Journal","volume":"36 1","pages":"65-71"},"PeriodicalIF":0.0,"publicationDate":"2009-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77260630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}