Maša Serec, B. Bajec, Davorina Petek, I. Švab, P. Selič
Background: This study explored how adequately the additive and mediational models could explain the relationships between personality traits and coping behavior in predicting burnout syndrome in professional soldiers of the Slovene Army. The additive model suggests that personality and coping are independent, unique contributors to maladjustment outcomes. The mediational model, on the other hand, suggests that personality factors predispose people to use particular coping strategies that tend to be less effective for adjustment. Methods: A total of 390 soldiers (87 % response rate) completed the Eysenck Personality Questionnaire, the Ways of Coping Questionnaire and the Maslach Burnout Inventory. Results: The structural equation modeling confirmed an adequate fit only of the additive model. As hypothesized, emotional exhaustion was positively associated with neuroticism and emotionoriented coping. Depersonalization was positively associated with psychoticism, and personal accomplishment was positively associated with extraversion and problem-oriented coping, and inversely with neuroticism and emotion-oriented coping. Conclusions: To reduce burnout in the Slovenian Army, it may be of great benefit to provide training of effective stress-coping mechanisms, and create peer support groups among soldiers. Such intervention should be especially beneficial for soldiers with a vulnerable personality structure (high neuroticism and psychoticism and low extraversion).
{"title":"A structural model of burnout syndrome, coping behavior and personality traits in professional soldiers of the Slovene armed forces","authors":"Maša Serec, B. Bajec, Davorina Petek, I. Švab, P. Selič","doi":"10.6016/812","DOIUrl":"https://doi.org/10.6016/812","url":null,"abstract":"Background: This study explored how adequately the additive and mediational models could explain the relationships between personality traits and coping behavior in predicting burnout syndrome in professional soldiers of the Slovene Army. The additive model suggests that personality and coping are independent, unique contributors to maladjustment outcomes. The mediational model, on the other hand, suggests that personality factors predispose people to use particular coping strategies that tend to be less effective for adjustment.\u0000Methods: A total of 390 soldiers (87 % response rate) completed the Eysenck Personality Questionnaire, the Ways of Coping Questionnaire and the Maslach Burnout Inventory.\u0000Results: The structural equation modeling confirmed an adequate fit only of the additive model. As hypothesized, emotional exhaustion was positively associated with neuroticism and emotionoriented coping. Depersonalization was positively associated with psychoticism, and personal accomplishment was positively associated with extraversion and problem-oriented coping, and inversely with neuroticism and emotion-oriented coping.\u0000Conclusions: To reduce burnout in the Slovenian Army, it may be of great benefit to provide training of effective stress-coping mechanisms, and create peer support groups among soldiers. Such intervention should be especially beneficial for soldiers with a vulnerable personality structure (high neuroticism and psychoticism and low extraversion).","PeriodicalId":49350,"journal":{"name":"Zdravniski Vestnik-Slovenian Medical Journal","volume":"6 1","pages":"326-336"},"PeriodicalIF":0.0,"publicationDate":"2012-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85798060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Research of low back pain (LBP) has been recently directed towards the younger age groups due to high predictive value for later life. The aim of the study was to assess the prevalence and risk factors for LBP in the Slovene population of young adults, which are yet unknown. Methods: In this cross sectional study firstgrade students at the Faculty of Sport (FS) and the Faculty of Chemistry (FC), University of Ljubljana, in 2009 were included. The Slovene translation of Chronic Pain Grade questionnaire was implemented. In the FS subgroup the associations between questionnaire results and results of the entrance examination were analyzed and a follow-up questionnaire survey was done after the 1st semester Results: The questionnaire was returned by 283 students. Average age was 19.9 (2.3) years. Lifelong and 6-month LBP prevalences were 87.3 % (83.1–90.9 %) and 63 % (57.4–68.6 %), respectively. Average LBP intensity was 36.6 (16.9) (range 0–90) out of 100 points, average disability was 18 (18.7) (range 0–83) out of 100 points. Females had higher intensity and disability scores. Competitors had higher pain disability scores than students engaging in sports at recreational level. Gender and level of physical activity were significant independent predictors of intensity and disability scores at multivariate linear regression. LBP was not associated with entrance test results and there were no important changes in the follow- up after the 1st semester in the FS students. Conclusions: We found high LBP prevalence, which was of moderate intensity and caused minor disability. LBP was more severe in females and associated with the level of physical activity. Information about LBP and preventive workout programs should be incorporated into study programs.
{"title":"Low back pain in physically active young adults","authors":"M. Pajek, M. Čuk, J. Pajek","doi":"10.6016/763","DOIUrl":"https://doi.org/10.6016/763","url":null,"abstract":"Background: Research of low back pain (LBP) has been recently directed towards the younger age groups due to high predictive value for later life. The aim of the study was to assess the prevalence and risk factors for LBP in the Slovene population of young adults, which are yet unknown. Methods: In this cross sectional study firstgrade students at the Faculty of Sport (FS) and the Faculty of Chemistry (FC), University of Ljubljana, in 2009 were included. The Slovene translation of Chronic Pain Grade questionnaire was implemented. In the FS subgroup the associations between questionnaire results and results of the entrance examination were analyzed and a follow-up questionnaire survey was done after the 1st semester Results: The questionnaire was returned by 283 students. Average age was 19.9 (2.3) years. Lifelong and 6-month LBP prevalences were 87.3 % (83.1–90.9 %) and 63 % (57.4–68.6 %), respectively. Average LBP intensity was 36.6 (16.9) (range 0–90) out of 100 points, average disability was 18 (18.7) (range 0–83) out of 100 points. Females had higher intensity and disability scores. Competitors had higher pain disability scores than students engaging in sports at recreational level. Gender and level of physical activity were significant independent predictors of intensity and disability scores at multivariate linear regression. LBP was not associated with entrance test results and there were no important changes in the follow- up after the 1st semester in the FS students. Conclusions: We found high LBP prevalence, which was of moderate intensity and caused minor disability. LBP was more severe in females and associated with the level of physical activity. Information about LBP and preventive workout programs should be incorporated into study programs.","PeriodicalId":49350,"journal":{"name":"Zdravniski Vestnik-Slovenian Medical Journal","volume":"7 1","pages":"205-217"},"PeriodicalIF":0.0,"publicationDate":"2012-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79244076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Trkov, A. Andlovic, Ingrid Berce, A. Štorman, M. Ravnik, M. Paragi
BACKGROUND Shiga toxin-producing E. coli or Vero cytotoxin-producing E. coli (VTEC) are characterised by the ability to produce either one or both cytotoxins referred to as Shiga toxin 1 (Stx1) and Shiga toxin 2 (Stx2). VTEC infection may result in life-threatening conditions such as haemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP). Due to different methods of monitoring and identification of these bacteria in recent years, the existing data on reported cases of VTEC infections probably do not reflect reality. Our study of VTEC strains isolated in different regions of Slovenia, showed serogroups, major virulence factors and specific epidemiological data that can serve as a basis for further laboratory and epidemiological surveillance of VTEC infections. METHODS A total of 66 VTEC strains, isolated from stool samples of patients with diarrhoea from the year 1993 to 2009, were collected at NIPH (National Institute of Public Health). The data of patient’s age and gender, onset of illness and clinical manifestation of disease were gathered. The serogroups of isolated strains were determined with antisera following manufacturer’s instructions. The ability to produce verocytotoxins was tested using the reversed passive latex agglutination method. The presence of genes for intimin (eae), enterohaemolysin (ehxA) and verotoxins (vtx1 and vtx2) were determined by polymerase chain reaction (PCR). RESULTS Infection with VTEC was encountered throughout the year, but most people were ill in the summer and autumn months. More than half of patients (57.6 %) were younger than five years. Collected VTEC strains belonged to serogroups O17, O26, O91, O103, O111, O113, O126, O128, O145, O148 and O157 (the most frequent were O157 and O26). A high percentage of VTEC strains showed the presence of intimin (86.4 %) and enterohaemolysin (86.4 %) genes. The gene for vtx1 was found in 22.7 % of strains, the vtx2 in 57.6 % of strains, while the presence of both genes was determined in 19.7 % of strains. The presence of the vtx2 gene was determined in all strains associated with HUS and TTP, most of them possessed the eae and ehxA genes too. These patients were mostly older people and young children. CONCLUSIONS Most infections with VTEC occurred in the warmer months of the year, most patient were small children. The severity of VTEC infection is determined by several factors such as the E. coli serogroup, the type of Shiga toxin produced and presence of other virulence genes. The most common serogroups among the study strains were O157 and O26. VTEC O26 has been the most commonly isolated serogroup in recent years, nevertheless more and more different serological groups began to emerge. In all strains associated with HUS and TTP, the vtx2 gene was determined. Further typing of verocytotoxin encoding genes will contribute to assess the risk for complications with VTEC infection. The study
{"title":"Verotoxigenic Escherichia coli isolated from human samples in Slovenia.","authors":"M. Trkov, A. Andlovic, Ingrid Berce, A. Štorman, M. Ravnik, M. Paragi","doi":"10.6016/672","DOIUrl":"https://doi.org/10.6016/672","url":null,"abstract":"BACKGROUND Shiga toxin-producing E. coli or Vero cytotoxin-producing E. coli (VTEC) are characterised by the ability to produce either one or both cytotoxins referred to as Shiga toxin 1 (Stx1) and Shiga toxin 2 (Stx2). VTEC infection may result in life-threatening conditions such as haemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP). Due to different methods of monitoring and identification of these bacteria in recent years, the existing data on reported cases of VTEC infections probably do not reflect reality. Our study of VTEC strains isolated in different regions of Slovenia, showed serogroups, major virulence factors and specific epidemiological data that can serve as a basis for further laboratory and epidemiological surveillance of VTEC infections. METHODS A total of 66 VTEC strains, isolated from stool samples of patients with diarrhoea from the year 1993 to 2009, were collected at NIPH (National Institute of Public Health). The data of patient’s age and gender, onset of illness and clinical manifestation of disease were gathered. The serogroups of isolated strains were determined with antisera following manufacturer’s instructions. The ability to produce verocytotoxins was tested using the reversed passive latex agglutination method. The presence of genes for intimin (eae), enterohaemolysin (ehxA) and verotoxins (vtx1 and vtx2) were determined by polymerase chain reaction (PCR). RESULTS Infection with VTEC was encountered throughout the year, but most people were ill in the summer and autumn months. More than half of patients (57.6 %) were younger than five years. Collected VTEC strains belonged to serogroups O17, O26, O91, O103, O111, O113, O126, O128, O145, O148 and O157 (the most frequent were O157 and O26). A high percentage of VTEC strains showed the presence of intimin (86.4 %) and enterohaemolysin (86.4 %) genes. The gene for vtx1 was found in 22.7 % of strains, the vtx2 in 57.6 % of strains, while the presence of both genes was determined in 19.7 % of strains. The presence of the vtx2 gene was determined in all strains associated with HUS and TTP, most of them possessed the eae and ehxA genes too. These patients were mostly older people and young children. CONCLUSIONS Most infections with VTEC occurred in the warmer months of the year, most patient were small children. The severity of VTEC infection is determined by several factors such as the E. coli serogroup, the type of Shiga toxin produced and presence of other virulence genes. The most common serogroups among the study strains were O157 and O26. VTEC O26 has been the most commonly isolated serogroup in recent years, nevertheless more and more different serological groups began to emerge. In all strains associated with HUS and TTP, the vtx2 gene was determined. Further typing of verocytotoxin encoding genes will contribute to assess the risk for complications with VTEC infection. The study ","PeriodicalId":49350,"journal":{"name":"Zdravniski Vestnik-Slovenian Medical Journal","volume":"114 1","pages":"32-43"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78940819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BACKGROUND In recent years a number of pointof- care troponin assays have emerged. There have been reports of discrepancies between the results of point-of-care and laboratory assays. We sought to compare the results of point-ofcare and laboratory troponin I assays in patients with suspected acute coronary syndromes. METHODS A retrospective study was performed comparing the results of point-of-care (i-STAT cardiac troponin I test, Abbott Point of Care) and laboratory troponin I analysis in patients with suspected acute coronary syndrome treated in the Internal Medicine Emergency Department, University Medical Centre Maribor, between 23 November and 21 December 2010, who had blood samples drawn simultaneously for pointof- care and laboratory troponin I analysis. RESULTS 112 patients were included in the analysis. There was an agreement between the results of point-of-care and laboratory troponin analysis in 105 (93.8 %) patients. If we consider the laboratory results as »gold standard« (diagnosis was based on laboratory troponin results), then 6 (5.4 %) false negative results and 1 (0.9 %) false positive result were found (sensitivity 81.2 %, specificity 98.7 %). However, there was no statistically significant difference between point-of-care and laboratory troponin I analysis (p = 0.125). CONCLUSIONS We detected lower sensitivity of point-of-care assay, but there was no statistically significant difference between point-of-care and laboratory troponin I analysis. We adopted a strategy of using point-of-care troponin assay primarily in patients at high-risk for acute coronary syndrome without ST elevation.
背景:近年来出现了许多护理点肌钙蛋白检测方法。有报告称，现场检测结果和实验室检测结果之间存在差异。我们试图比较疑似急性冠状动脉综合征患者的即时护理和实验室肌钙蛋白I检测结果。方法回顾性比较2010年11月23日至12月21日在马里博尔大学医学中心内科急诊科治疗的疑似急性冠状动脉综合征患者的即时(I - stat心脏肌钙蛋白I检测，雅培即时(Abbott Point of Care))和实验室肌钙蛋白I分析结果，这些患者同时抽取血液进行即时和实验室肌钙蛋白I分析。结果112例患者纳入分析。105例(93.8%)患者的现场肌钙蛋白分析结果与实验室肌钙蛋白分析结果一致。如果我们将实验室结果视为“金标准”(诊断基于实验室肌钙蛋白结果)，则发现6例(5.4%)假阴性结果和1例(0.9%)假阳性结果(敏感性81.2%，特异性98.7%)。然而，现场护理和实验室肌钙蛋白I分析之间没有统计学上的显著差异(p = 0.125)。结论:定点护理法的敏感性较低，但定点护理法与实验室肌钙蛋白I分析的差异无统计学意义。我们采用即时肌钙蛋白检测的策略，主要用于无ST段抬高的急性冠状动脉综合征高危患者。
{"title":"Comparison of point-of-care and laboratory troponin I assays.","authors":"A. Markota, M. Bernhardt, M. Palfy","doi":"10.6016/655","DOIUrl":"https://doi.org/10.6016/655","url":null,"abstract":"BACKGROUND\u0000In recent years a number of pointof- care troponin assays have emerged. There have been reports of discrepancies between the results of point-of-care and laboratory assays. We sought to compare the results of point-ofcare and laboratory troponin I assays in patients with suspected acute coronary syndromes.\u0000\u0000METHODS\u0000A retrospective study was performed comparing the results of point-of-care (i-STAT cardiac troponin I test, Abbott Point of Care) and laboratory troponin I analysis in patients with suspected acute coronary syndrome treated in the Internal Medicine Emergency Department, University Medical Centre Maribor, between 23 November and 21 December 2010, who had blood samples drawn simultaneously for pointof- care and laboratory troponin I analysis.\u0000\u0000RESULTS\u0000112 patients were included in the analysis. There was an agreement between the results of point-of-care and laboratory troponin analysis in 105 (93.8 %) patients. If we consider the laboratory results as »gold standard« (diagnosis was based on laboratory troponin results), then 6 (5.4 %) false negative results and 1 (0.9 %) false positive result were found (sensitivity 81.2 %, specificity 98.7 %). However, there was no statistically significant difference between point-of-care and laboratory troponin I analysis (p = 0.125).\u0000\u0000CONCLUSIONS\u0000We detected lower sensitivity of point-of-care assay, but there was no statistically significant difference between point-of-care and laboratory troponin I analysis. We adopted a strategy of using point-of-care troponin assay primarily in patients at high-risk for acute coronary syndrome without ST elevation.","PeriodicalId":49350,"journal":{"name":"Zdravniski Vestnik-Slovenian Medical Journal","volume":"17 1","pages":"905-908"},"PeriodicalIF":0.0,"publicationDate":"2011-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87479622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ultrasound of the neck arteries is a reliable, noninvasive and safe investigation. It enables the evaluation of atherosclerosis in the primary prevention of vascular diseases and has an even more important role in the secondary prevention of ischemic stroke. A quarter of ischemic infarctions can be explained by hemodynamically important carotid stenosis and subsequent thrombembolism. Patients with a hemodynamically important carotid stenosis have a bad prognosis which changes dramatically if they receive surgical, endovascular or even intensive drug treatment. Due to time and human resource limitations we can not perform ultrasound of the neck arteries in the entire population. Patients who need urgent investigation are lost in the crowd of other not so urgent patients, and therefore we wrote the present guidelines. Carotid ultrasound is an urgent investigation for most symptomatic patients – ABCD score enables evaluation of emergency. In the group of asymptomatic patients screening of particular endangered groups of patients is recommended. The evaluation of emergency should be rational and also based on age and clinical data of the patient. A referring physician should follow the present guidelines and make decision about the urgency of the investigation.
{"title":"Indications for Ultrasound of the Neck Arteries","authors":"J. P. Oblak, M. Zaletel, B. Žvan","doi":"10.6016/196","DOIUrl":"https://doi.org/10.6016/196","url":null,"abstract":"Ultrasound of the neck arteries is a reliable, noninvasive and safe investigation. It enables the evaluation of atherosclerosis in the primary prevention of vascular diseases and has an even more important role in the secondary prevention of ischemic stroke. A quarter of ischemic infarctions can be explained by hemodynamically important carotid stenosis and subsequent thrombembolism. Patients with a hemodynamically important carotid stenosis have a bad prognosis which changes dramatically if they receive surgical, endovascular or even intensive drug treatment. Due to time and human resource limitations we can not perform ultrasound of the neck arteries in the entire population. Patients who need urgent investigation are lost in the crowd of other not so urgent patients, and therefore we wrote the present guidelines. Carotid ultrasound is an urgent investigation for most symptomatic patients – ABCD score enables evaluation of emergency. In the group of asymptomatic patients screening of particular endangered groups of patients is recommended. The evaluation of emergency should be rational and also based on age and clinical data of the patient. A referring physician should follow the present guidelines and make decision about the urgency of the investigation.","PeriodicalId":49350,"journal":{"name":"Zdravniski Vestnik-Slovenian Medical Journal","volume":"5 1","pages":"553-560"},"PeriodicalIF":0.0,"publicationDate":"2011-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78962757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Farzad Soleimani, F. Moll, D. Wallace, J. Bismuth, B. Geršak
The article is discussing the development of robotic surgery from its beginnings to the present. Introducing the early stages of development thinking on the use of robots in medicine, special emphasis is devoted to the latest knowledge in the creation of flexible robots. Described are the advantages and disadvantages of robotic surgery in different applications and also look to the future: where it will and can be implemented. A special emphasis is put toward robotic learning, simulations, and in this respect also the question how to develop new skills. is potentially answered.
{"title":"Robots and Medicine – Shaping and Defining the Future of Surgery, Endovascular Surgery, Electrophysiology and Interventional Radiology","authors":"Farzad Soleimani, F. Moll, D. Wallace, J. Bismuth, B. Geršak","doi":"10.6016/203","DOIUrl":"https://doi.org/10.6016/203","url":null,"abstract":"The article is discussing the development of robotic surgery from its beginnings to the present. Introducing the early stages of development thinking on the use of robots in medicine, special emphasis is devoted to the latest knowledge in the creation of flexible robots. Described are the advantages and disadvantages of robotic surgery in different applications and also look to the future: where it will and can be implemented. A special emphasis is put toward robotic learning, simulations, and in this respect also the question how to develop new skills. is potentially answered.","PeriodicalId":49350,"journal":{"name":"Zdravniski Vestnik-Slovenian Medical Journal","volume":"353 1","pages":"614-631"},"PeriodicalIF":0.0,"publicationDate":"2011-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75495388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Šuškovič, T. Camlek, M. Gril, I. Hudoklin, A. Klobucar, I. Koren, Marjan Koterle, Liljana Terzin Krajinović, B. Meznar, Aljoša Silič
Background: As prevalence of adult asthma in Slovenia was unknown, a research was performed to disclose this epidemiologic parameter of asthma in Slovenian adults aged 18 to 65 years.
{"title":"Prevalence of asthma in adults in Slovenia","authors":"S. Šuškovič, T. Camlek, M. Gril, I. Hudoklin, A. Klobucar, I. Koren, Marjan Koterle, Liljana Terzin Krajinović, B. Meznar, Aljoša Silič","doi":"10.6016/110","DOIUrl":"https://doi.org/10.6016/110","url":null,"abstract":"Background: As prevalence of adult asthma in Slovenia was unknown, a research was performed to disclose this epidemiologic parameter of asthma in Slovenian adults aged 18 to 65 years.","PeriodicalId":49350,"journal":{"name":"Zdravniski Vestnik-Slovenian Medical Journal","volume":"24 1","pages":"451-457"},"PeriodicalIF":0.0,"publicationDate":"2011-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80404769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: There is a lack of clinical trials on the success of embryo culture in different commercial culture systems in the programme of in vitro fertilization (IVF). In our prospective study, embryo development was compared in two sequential media. Methods: The oocytes from each of 62 patients, treated by IVF/ICSI, were distributed into two groups for 5-day culture in the BlastAssist® System (Medicult, Denmark) (Group 1, n = 421) and in the GIII Series™ (Vitrolife, Sweden) (Group 2, n = 415) media. The dynamics of embryo development, implantation and pregnancy rates were compared between groups. Results: The differences between Groups 1 and 2 were first noted on day 3 when GIII yielded more fast-cleaving (> 6 cells) nonfragmented embryos (31.3 % vs. 44.4 %, P < 0.01). On day 4 however, a larger number of compact embryos was found in Group 1 (42.2 % vs. 28.7 %, P < 0.005). The percentage of blastocysts or compact morulae on day 5 was the same in both groups (59.6 % vs. 55.6 %). But expanded blastocysts of optimal quality with oval inner-cell-mass developed more frequently in Group 1 (29.2 % vs. 17.7 %, P < 0.05), and therefore more transfers were performed exclusively with Group 1 embryos (28 vs. 17). Pregnancy and implantation rates were the same in both groups (53.6 % vs. 52.9 % and 34.7 % vs. 34.2 %, respectively). Conclusions: Although the GIII Series™ yields more fast-cleaving embryos on day 3, embryo compaction (morula) and cavitation (blastocoel) start earlier in the BlastAssist® System media. BlastAssist® System therefore allows easier selection of embryos for transfer on day 5.
背景:在体外受精(IVF)项目中，缺乏不同商业培养系统中胚胎培养成功的临床试验。在我们的前瞻性研究中，胚胎发育在两种顺序培养基中进行了比较。方法:将62例接受IVF/ICSI治疗的患者的卵母细胞分为两组，分别在BlastAssist®System(丹麦Medicult公司)(第1组，n = 421)和GIII Series™(瑞典Vitrolife公司)(第2组，n = 415)培养基中培养5 d。比较各组胚胎发育动态、着床率和妊娠率。结果:组1和组2的差异首次出现在第3天，GIII产生了更多的快速切割(> 6个细胞)非碎片化胚胎(31.3%比44.4%，P < 0.01)。第4天，第1组致密胚数量较多(42.2% vs. 28.7%， P < 0.005)。第5天，两组的囊胚或致密胚的百分比相同(59.6%比55.6%)。但在第1组中，具有最佳质量的卵圆形内细胞团的膨大囊胚的发育频率更高(29.2%比17.7%，P < 0.05)，因此只使用第1组胚胎进行更多的移植(28比17)。两组的妊娠和着床率相同(分别为53.6%对52.9%，34.7%对34.2%)。结论:尽管GIII系列™在第3天产生更多的快速分裂胚胎，但在BlastAssist®系统培养基中，胚胎压实(桑葚胚)和空化(囊胚腔)开始得更早。因此，BlastAssist®系统允许在第5天更容易地选择胚胎进行移植。
{"title":"Dynamics of human embryo development in two types of blastocyst media: a prospective trial on sibling oocytes","authors":"B. Kovačič, V. Vlaisavljevic","doi":"10.6016/103","DOIUrl":"https://doi.org/10.6016/103","url":null,"abstract":"Background: There is a lack of clinical trials on the success of embryo culture in different commercial culture systems in the programme of in vitro fertilization (IVF). In our prospective study, embryo development was compared in two sequential media.\u0000Methods: The oocytes from each of 62 patients, treated by IVF/ICSI, were distributed into two groups for 5-day culture in the BlastAssist® System (Medicult, Denmark) (Group 1, n = 421) and in the GIII Series™ (Vitrolife, Sweden) (Group 2, n = 415) media. The dynamics of embryo development, implantation and pregnancy rates were compared between groups.\u0000Results: The differences between Groups 1 and 2 were first noted on day 3 when GIII yielded more fast-cleaving (> 6 cells) nonfragmented embryos (31.3 % vs. 44.4 %, P < 0.01). On day 4 however, a larger number of compact embryos was found in Group 1 (42.2 % vs. 28.7 %, P < 0.005). The percentage of blastocysts or compact morulae on day 5 was the same in both groups (59.6 % vs. 55.6 %). But expanded blastocysts of optimal quality with oval inner-cell-mass developed more frequently in Group 1 (29.2 % vs. 17.7 %, P < 0.05), and therefore more transfers were performed exclusively with Group 1 embryos (28 vs. 17). Pregnancy and implantation rates were the same in both groups (53.6 % vs. 52.9 % and 34.7 % vs. 34.2 %, respectively).\u0000Conclusions: Although the GIII Series™ yields more fast-cleaving embryos on day 3, embryo compaction (morula) and cavitation (blastocoel) start earlier in the BlastAssist® System media. BlastAssist® System therefore allows easier selection of embryos for transfer on day 5.","PeriodicalId":49350,"journal":{"name":"Zdravniski Vestnik-Slovenian Medical Journal","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2011-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81316097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Post-operative hernia is the most frequent complication following abdominal surgery. Hernia repair used to be done by direct suture of the abdominal wall, but nowadays mesh placement is the method of choice. It has been demonstrated that the retromuscular position of the mesh is most appropriate. The treatment results and the patients’ views of the treatment are presented. Methods: Treatment results were analyzed retrospectively, and the patients who had been operated on for postoperative hernia were interviewed. Results: Between January 2004 and December 2008, 150 patients with postoperative hernia were operated on. The analysis 2 (1.3 %) refused to cooperate, and 5 patients (3.3 %) died. The mean age of the interviewees was 64.4 years and the mean hospital stay was 4.2 days. During hospital stay, 14 patients out of the total of 121 interviewed patients (11.6 %) experienced complications and 6 patients (4.9 %) had a wound infection. During the mean observation period of 36 months, 5 patients (4.1 %) presented with recurrences. The mean duration of postoperative pain was 6.6 weeks; 35 patients (28.9 %) continued taking analgesics at home; 22 patients (18.2 %) still felt pain in the wound during the interview. The mean recovery to normal, daily activities took 8 weeks. Nearly one quarter of the patients (23.9 %) reported still being careful about engaging in daily activities. The majority of the patients, i.e. 116 patients (95.9 %), were satisfied with the surgical procedure and would recommend it to a relative in the same situation. Conclusions: The retromuscular mesh placement for postoperative hernia repair results in a low rate of recurrences and postoperative complications. Complications are more common in patients admitted due to incarceration and in patients having suffered from stoma. Pain inflicted by postoperative hernia repair is an underrated with treatment results.
{"title":"Long-term results of incisional hernia repair with retromuscular mesh","authors":"M. Rems, Sandra Tušar, Matej Dolenc","doi":"10.6016/83","DOIUrl":"https://doi.org/10.6016/83","url":null,"abstract":"Background: Post-operative hernia is the most frequent complication following abdominal surgery. Hernia repair used to be done by direct suture of the abdominal wall, but nowadays mesh placement is the method of choice. It has been demonstrated that the retromuscular position of the mesh is most appropriate. The treatment results and the patients’ views of the treatment are presented.\u0000Methods: Treatment results were analyzed retrospectively, and the patients who had been operated on for postoperative hernia were interviewed.\u0000Results: Between January 2004 and December 2008, 150 patients with postoperative hernia were operated on. The analysis 2 (1.3 %) refused to cooperate, and 5 patients (3.3 %) died. The mean age of the interviewees was 64.4 years and the mean hospital stay was 4.2 days. During hospital stay, 14 patients out of the total of 121 interviewed patients (11.6 %) experienced complications and 6 patients (4.9 %) had a wound infection. During the mean observation period of 36 months, 5 patients (4.1 %) presented with recurrences. The mean duration of postoperative pain was 6.6 weeks; 35 patients (28.9 %) continued taking analgesics at home; 22 patients (18.2 %) still felt pain in the wound during the interview. The mean recovery to normal, daily activities took 8 weeks. Nearly one quarter of the patients (23.9 %) reported still being careful about engaging in daily activities. The majority of the patients, i.e. 116 patients (95.9 %), were satisfied with the surgical procedure and would recommend it to a relative in the same situation.\u0000Conclusions: The retromuscular mesh placement for postoperative hernia repair results in a low rate of recurrences and postoperative complications. Complications are more common in patients admitted due to incarceration and in patients having suffered from stoma. Pain inflicted by postoperative hernia repair is an underrated with treatment results.","PeriodicalId":49350,"journal":{"name":"Zdravniski Vestnik-Slovenian Medical Journal","volume":"210 1","pages":"268-275"},"PeriodicalIF":0.0,"publicationDate":"2011-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85235197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract: Chronic heart failure is a clinical syndrome that can result from many cardiac diseases, the most common being cardiomyopathies and coronary artery disease. According to recent epidemiological data, heart failure is the only cardiologic entity whose prevalence is actually increasing and is present in 2–5 % of general population and in 10 % of people older than 65 years. The scope of this paper includes algorithms of initial heart failure diagnostic work-up , medical management and contemporary non-medical treatment options.
{"title":"Modern treatment methods for heart failure.","authors":"B. Vrtovec, G. Poglajen","doi":"10.6016/86","DOIUrl":"https://doi.org/10.6016/86","url":null,"abstract":"Abstract: Chronic heart failure is a clinical syndrome that can result from many cardiac diseases, the most common being cardiomyopathies and coronary artery disease. According to recent epidemiological data, heart failure is the only cardiologic entity whose prevalence is actually increasing and is present in 2–5 % of general population and in 10 % of people older than 65 years. The scope of this paper includes algorithms of initial heart failure diagnostic work-up , medical management and contemporary non-medical treatment options.","PeriodicalId":49350,"journal":{"name":"Zdravniski Vestnik-Slovenian Medical Journal","volume":"10 1","pages":"302-315"},"PeriodicalIF":0.0,"publicationDate":"2011-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78756964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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