首页 > 最新文献

Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland最新文献

英文 中文
Innovative use of TXA and protamine-infused hydrogels to reduce postoperative bleeding in breast surgery for heparin-anticoagulated patients "创新性地使用注入 TXA 和原胺的水凝胶来减少肝素抗凝患者乳房手术的术后出血"。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-07-22 DOI: 10.1016/j.surge.2024.07.002
Michael James , Viren S. Sehgal
{"title":"Innovative use of TXA and protamine-infused hydrogels to reduce postoperative bleeding in breast surgery for heparin-anticoagulated patients","authors":"Michael James , Viren S. Sehgal","doi":"10.1016/j.surge.2024.07.002","DOIUrl":"10.1016/j.surge.2024.07.002","url":null,"abstract":"","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":"22 5","pages":"Page e189"},"PeriodicalIF":2.3,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141753211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The place of splenectomy in the therapeutic management of patients with infective endocarditis and splenic abscess: A single center experience and a literature review 脾切除术在感染性心内膜炎和脾脓肿患者治疗中的地位:单中心经验与文献综述。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-07-18 DOI: 10.1016/j.surge.2024.06.008
Corina-Elena Minciuna , Beatrice Tivadar , Vlad Costin Ilie , Ruxandra Daniela Fota , Alina Teodora Timisescu , Vlad Anton Iliescu , Ioan Mircea Coman , Gabriela Droc , Andrei George Iosifescu , Catalin Vasilescu

Introduction

Infective endocarditis(IE) has a low incidence, but it remains a serious disease with high mortality rates. Only 5 % of these patients will develop a splenic abscess, and the number of patients that have IE and a splenic abscess requiring surgery is low. The current guidelines recommend that splenectomy should be performed prior to valve replacement, but there is no strong evidence to support this statement and no evidence to clearly endorse the order in which the surgical interventions should be performed. The objective of this review and case series is to establish the proper treatment strategy, to assess the adequate order of the surgical interventions and to clarify the role of percutaneous drainage in the management of these patients.

Material and Methods

All patients with infective endocarditis and splenic abscess who underwent surgery in our institution, between January 2008 and December 2020 were included in this study, excluding patients which had cardiac device related endocarditis. Literature review on the matter included a number of 30 studies which were selected from the PubMed database.

Results

Assessing the literature and case series no reinfection was reported for simultaneously performing splenectomy(S) and valvular surgery(VS) nor for VS followed by S.

Conclusion

Percutaneous drainage of the splenic abscesses is a feasible solution as definitive therapy in high-risk patients or as bridge therapy. Additional studies are needed, even though they are difficult to conduct, therefore a national/international infectious endocarditis register may be of use to clarify these challenges.
导言:感染性心内膜炎(IE)的发病率很低,但仍是一种死亡率很高的严重疾病。感染性心内膜炎患者中只有5%会发展为脾脓肿,因此需要手术治疗的感染性心内膜炎和脾脓肿患者人数很少。目前的指南建议应在瓣膜置换术前进行脾切除术,但没有有力的证据支持这一说法,也没有证据明确认可手术干预的顺序。本综述和病例系列旨在确定正确的治疗策略,评估手术干预的适当顺序,并明确经皮引流在这些患者治疗中的作用:本研究纳入了2008年1月至2020年12月期间在我院接受手术治疗的所有感染性心内膜炎和脾脓肿患者,但不包括与心脏设备相关的心内膜炎患者。相关文献综述包括从 PubMed 数据库中选取的 30 项研究:结果:通过对文献和病例系列的评估,没有发现同时进行脾切除术(S)和瓣膜手术(VS)或先进行VS再进行S的再感染病例:结论:脾脓肿经皮引流术是一种可行的方法,可作为高危患者的最终治疗或过渡治疗。尽管难以开展,但仍需进行更多的研究,因此,全国性/国际性的感染性心内膜炎登记册可能有助于澄清这些难题。
{"title":"The place of splenectomy in the therapeutic management of patients with infective endocarditis and splenic abscess: A single center experience and a literature review","authors":"Corina-Elena Minciuna ,&nbsp;Beatrice Tivadar ,&nbsp;Vlad Costin Ilie ,&nbsp;Ruxandra Daniela Fota ,&nbsp;Alina Teodora Timisescu ,&nbsp;Vlad Anton Iliescu ,&nbsp;Ioan Mircea Coman ,&nbsp;Gabriela Droc ,&nbsp;Andrei George Iosifescu ,&nbsp;Catalin Vasilescu","doi":"10.1016/j.surge.2024.06.008","DOIUrl":"10.1016/j.surge.2024.06.008","url":null,"abstract":"<div><h3>Introduction</h3><div>Infective endocarditis(IE) has a low incidence, but it remains a serious disease with high mortality rates. Only 5 % of these patients will develop a splenic abscess<span><span>, and the number of patients that have IE and a splenic abscess requiring surgery is low. The current guidelines recommend that splenectomy should be performed prior to valve replacement, but there is no strong evidence to support this statement and no evidence to clearly endorse the order in which the surgical interventions should be performed. The objective of this review and case series is to establish the proper treatment strategy, to assess the adequate order of the surgical interventions and to clarify the role of </span>percutaneous drainage in the management of these patients.</span></div></div><div><h3>Material and Methods</h3><div>All patients with infective endocarditis and splenic abscess who underwent surgery in our institution, between January 2008 and December 2020 were included in this study, excluding patients which had cardiac device related endocarditis. Literature review on the matter included a number of 30 studies which were selected from the PubMed database.</div></div><div><h3>Results</h3><div>Assessing the literature and case series no reinfection was reported for simultaneously performing splenectomy(S) and valvular surgery(VS) nor for VS followed by S.</div></div><div><h3>Conclusion</h3><div>Percutaneous drainage of the splenic abscesses is a feasible solution as definitive therapy in high-risk patients or as bridge therapy. Additional studies are needed, even though they are difficult to conduct, therefore a national/international infectious endocarditis register may be of use to clarify these challenges.</div></div>","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":"22 6","pages":"Pages e202-e207"},"PeriodicalIF":2.3,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141724888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gender more than ethnicity or disability influences the choice of a career in cardiothoracic surgery by United Kingdom medical students 性别比种族或残疾更能影响英国医科学生对心胸外科职业的选择。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-07-18 DOI: 10.1016/j.surge.2024.06.002
Sathyan Gnanalingham , Farah Bhatti , Rana Sayeed

Objectives

Cardiothoracic surgery has reported poor equality, diversity, and inclusion amongst its faculty [1–3]. We explored how gender, ethnicity, and disability influence medical students’ interest in cardiothoracic surgery as a career choice, as well as overall exposure to cardiothoracic surgery in the undergraduate curriculum.

Methods

We distributed a 26-item Google Forms online survey to student members of a medical education group from all 37 UK medical schools via social media. Respondents were asked to rank different ‘factors of interest’ on a 1–5 Likert scale (1 ​= ​not important at all, 5 ​= ​very important) and were encouraged to add free-text comments. Quantitative data were analysed using SPSS.

Results

There were 258 respondents, 62% identifying as female and 38% male. Respondents' ethnicities were 45% White, 44% Asian or Asian British, and 11% from other ethnic groups. 11% of respondents confirmed ‘long-standing illness or disability’.

Men were almost twice as likely to consider a career in cardiothoracic surgery than women (33% vs 19%; p ​< ​0.001). Women were more likely than men to feel that their gender, lack of a similarly gendered mentor, and long working hours were important factors when considering cardiothoracic surgery as a career.

Ethnicity of the respondent did not appear to affect how they perceived the challenges of a career in cardiothoracic surgery. Interestingly, ‘long-standing illness or disability’ did not significantly affect the decision making to consider this specialty as a career.

Overall, 73% of respondents reported not having adequate exposure to cardiothoracic surgery at medical school and agreed they would benefit from more time.

Conclusions

Female medical students felt their gender, lack of same-sex role models, and perceived long working hours were barriers in considering cardiothoracic surgery as a career. All students felt the need for more exposure to Cardiothoracic Surgery in the undergraduate curriculum.

目的:据报道,心胸外科的师资队伍在平等性、多样性和包容性方面存在不足[1-3]。我们探讨了性别、种族和残疾如何影响医学生对心胸外科学作为职业选择的兴趣,以及在本科课程中接触心胸外科学的总体情况:我们通过社交媒体向英国 37 所医学院的医学教育小组的学生成员发放了一份包含 26 个项目的谷歌表格在线调查。我们要求受访者用 1-5 级李克特量表(1 = 完全不重要,5 = 非常重要)对不同的 "关注因素 "进行排序,并鼓励他们添加自由文本评论。采用 SPSS 对定量数据进行了分析:共有 258 位受访者,其中 62% 为女性,38% 为男性。45% 的受访者为白人,44% 为亚裔或英国亚裔,11% 为其他族裔。11%的受访者确认 "长期患病或残疾"。男性考虑从事心胸外科工作的可能性几乎是女性的两倍(33% 对 19%;P 结论:男性考虑从事心胸外科工作的可能性是女性的两倍:女医科学生认为自己的性别、缺乏同性榜样以及认为工作时间长是她们考虑从事心胸外科的障碍。所有学生都认为有必要在本科课程中更多地接触心胸外科。
{"title":"Gender more than ethnicity or disability influences the choice of a career in cardiothoracic surgery by United Kingdom medical students","authors":"Sathyan Gnanalingham ,&nbsp;Farah Bhatti ,&nbsp;Rana Sayeed","doi":"10.1016/j.surge.2024.06.002","DOIUrl":"10.1016/j.surge.2024.06.002","url":null,"abstract":"<div><h3>Objectives</h3><p>Cardiothoracic surgery has reported poor equality, diversity, and inclusion amongst its faculty [1–3]. We explored how gender, ethnicity, and disability influence medical students’ interest in cardiothoracic surgery as a career choice, as well as overall exposure to cardiothoracic surgery in the undergraduate curriculum.</p></div><div><h3>Methods</h3><p>We distributed a 26-item Google Forms online survey to student members of a medical education group from all 37 UK medical schools via social media. Respondents were asked to rank different ‘factors of interest’ on a 1–5 Likert scale (1 ​= ​not important at all, 5 ​= ​very important) and were encouraged to add free-text comments. Quantitative data were analysed using SPSS.</p></div><div><h3>Results</h3><p>There were 258 respondents, 62% identifying as female and 38% male. Respondents' ethnicities were 45% White, 44% Asian or Asian British, and 11% from other ethnic groups. 11% of respondents confirmed ‘long-standing illness or disability’.</p><p>Men were almost twice as likely to consider a career in cardiothoracic surgery than women (33% vs 19%; p ​&lt; ​0.001). Women were more likely than men to feel that their gender, lack of a similarly gendered mentor, and long working hours were important factors when considering cardiothoracic surgery as a career.</p><p>Ethnicity of the respondent did not appear to affect how they perceived the challenges of a career in cardiothoracic surgery. Interestingly, ‘long-standing illness or disability’ did not significantly affect the decision making to consider this specialty as a career.</p><p>Overall, 73% of respondents reported not having adequate exposure to cardiothoracic surgery at medical school and agreed they would benefit from more time.</p></div><div><h3>Conclusions</h3><p>Female medical students felt their gender, lack of same-sex role models, and perceived long working hours were barriers in considering cardiothoracic surgery as a career. All students felt the need for more exposure to Cardiothoracic Surgery in the undergraduate curriculum.</p></div>","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":"22 5","pages":"Pages 286-289"},"PeriodicalIF":2.3,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1479666X2400060X/pdfft?md5=b6cce12e3ac79e335c27393ba4763dfd&pid=1-s2.0-S1479666X2400060X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141727981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of perioperative intravenous iron infusion in femoral fracture surgery: A systematic review and meta-analysis of randomised controlled trials 股骨骨折手术围手术期静脉输注铁剂的结果:随机对照试验的系统回顾和荟萃分析。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-07-14 DOI: 10.1016/j.surge.2024.07.005
Wen Xian Low , Hetta Friend , Joseph Dulleston , Sophie Heppenstall , Kate Spacey , Ignatius Liew

Background

Patient blood management recommends the use of intravenous (IV) iron infusion to reduce inappropriate blood transfusion perioperatively for anaemic surgical patients. However, evidence regarding its use in urgent femoral fracture surgery is limited. This systematic review aims to collate the current evidence regarding the utilisation of IV iron in femoral fracture surgery.

Method

MEDLINE, Embase, Cochrane CENTRAL, Clinicaltrials.gov, and the WHO ICTRP databases were systematically searched for randomised controlled trials (RCT) comparing the outcomes of perioperative IV iron infusion with placebo in adults requiring surgical management for femoral fractures. Risk ratios (RR) were calculated using the Mantel-Haenszel method for dichotomous outcomes, and mean differences (MD) were calculated with the inverse-variance method for continuous outcomes.

Results

Six RCTs with 1292 patients were included. No statistically significant difference was found in the proportion of patients receiving red blood cell (RBC) transfusion (RR = 0.87, 95%CI: 0.75; 1.01, p = 0.058) between groups. Statistically significant difference in postoperative haemoglobin concentration was found between groups measured between day 4–7 of admission (MD = 1.93 g/L, 95%CI: 0.48; 3.39, p = 0.024), but not clinically significant. No statistically significant differences were found between groups in mortality rate, length of hospital stay, infection rate, or return to home rate.

Conclusion

Current evidence indicates that IV iron infusion alone does not provide any clinically significant benefit in femoral fracture surgery. Further high-quality RCTs are needed to explore its synergistic potential when used in combination with other perioperative optimisation methods, including tranexamic acid, erythropoietin and cell salvage.

背景:患者血液管理建议使用静脉输注铁剂,以减少贫血手术患者围手术期的不当输血。然而,在股骨骨折紧急手术中使用静脉输注的证据却很有限。本系统性综述旨在整理有关股骨骨折手术中静脉输注铁剂的现有证据:方法:系统检索了 MEDLINE、Embase、Cochrane CENTRAL、Clinicaltrials.gov 和 WHO ICTRP 数据库中的随机对照试验 (RCT),比较了股骨骨折需要手术治疗的成人围手术期静脉输注铁剂与安慰剂的疗效。对二分结果采用曼特尔-海恩泽尔法计算风险比(RR),对连续结果采用逆方差法计算平均差(MD):结果:共纳入六项研究,1292 名患者。各组间接受红细胞(RBC)输注的患者比例差异无统计学意义(RR=0.87,95%CI:0.75;1.01,P=0.058)。入院第 4-7 天测量的术后血红蛋白浓度在组间存在显著统计学差异(MD = 1.93 g/L,95%CI:0.48;3.39,p = 0.024),但无临床意义。在死亡率、住院时间、感染率或回家率方面,各组之间没有发现明显的统计学差异:结论:目前的证据表明,单纯静脉输注铁剂对股骨骨折手术并无任何临床意义。需要进一步开展高质量的研究性试验,以探索其与其他围手术期优化方法(包括氨甲环酸、促红细胞生成素和细胞抢救)联合使用时的协同潜力。
{"title":"Outcomes of perioperative intravenous iron infusion in femoral fracture surgery: A systematic review and meta-analysis of randomised controlled trials","authors":"Wen Xian Low ,&nbsp;Hetta Friend ,&nbsp;Joseph Dulleston ,&nbsp;Sophie Heppenstall ,&nbsp;Kate Spacey ,&nbsp;Ignatius Liew","doi":"10.1016/j.surge.2024.07.005","DOIUrl":"10.1016/j.surge.2024.07.005","url":null,"abstract":"<div><h3>Background</h3><p><span><span>Patient blood management recommends the use of intravenous (IV) iron infusion to reduce inappropriate blood transfusion perioperatively for anaemic surgical patients. However, evidence regarding its use in urgent </span>femoral fracture surgery is limited. This </span>systematic review<span> aims to collate the current evidence regarding the utilisation of IV iron in femoral fracture surgery.</span></p></div><div><h3>Method</h3><p><span>MEDLINE, Embase, Cochrane CENTRAL, Clinicaltrials.gov, and the WHO ICTRP databases were systematically searched for </span>randomised controlled trials (RCT) comparing the outcomes of perioperative IV iron infusion with placebo in adults requiring surgical management for femoral fractures. Risk ratios (RR) were calculated using the Mantel-Haenszel method for dichotomous outcomes, and mean differences (MD) were calculated with the inverse-variance method for continuous outcomes.</p></div><div><h3>Results</h3><p><span>Six RCTs with 1292 patients were included. No statistically significant difference was found in the proportion of patients receiving red blood cell (RBC) transfusion (RR = 0.87, 95%CI: 0.75; 1.01, p = 0.058) between groups. Statistically significant difference in postoperative haemoglobin concentration was found between groups measured between day 4–7 of admission (MD = 1.93 g/L, 95%CI: 0.48; 3.39, p = 0.024), but not clinically significant. No statistically significant differences were found between groups in </span>mortality rate, length of hospital stay, infection rate, or return to home rate.</p></div><div><h3>Conclusion</h3><p><span>Current evidence indicates that IV iron infusion alone does not provide any clinically significant benefit in femoral fracture surgery. Further high-quality RCTs are needed to explore its synergistic potential when used in combination with other perioperative optimisation methods, including tranexamic acid, </span>erythropoietin and cell salvage.</p></div>","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":"22 5","pages":"Pages e171-e180"},"PeriodicalIF":2.3,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141621269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distant lymph node metastasis in differentiated thyroid cancer: A population-based cohort study. 分化型甲状腺癌的远处淋巴结转移:基于人群的队列研究
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-07-11 DOI: 10.1016/j.surge.2024.07.004
Ying Ding, Ruixin Zhou

Background: Cervical lymph node metastasis (LNM) is the most common clinical event in patients with differentiated thyroid cancer (DTC). However, the incidence, pattern, treatment, and prognosis of distant LNM are yet to be reported.

Methods: DTC patients with distant LNM were identified from the Surveillance, Epidemiology, and End Results (SEER) database between 2016 and 2020. Multivariate models and propensity score matching (PSM) were used to account for the effects of covariates. The Kaplan-Meier method was used to evaluate the overall survival (OS) and cancer-specific survival (CSS). A nomogram was established to predict the probability of distant LNM in DTC patients, with calibration and Receiver Operating Characteristic (ROC) curves utilized to validate the nomogram's accuracy.

Results: Of the 42,339 DTC patients screened, 100 (0.24 %) patients presented with distant LNM. Risk factors including age, sex, T stage, N stage, bone metastasis, brain metastasis, and lung metastasis were included in the nomogram to predict the probability of distant LNM. The calibration curve of the nomogram was close to the ideal diagonal line and the area under the curve (AUC) of the ROC curve is 0.953. Distant LNM showed a worse prognosis after adjusting for confounders compared with non-distant LNM (P < 0.05). Remarkably, radioactive iodine (RAI) therapy did not improve the OS and CSS in DTC patients with distant LNM in the overall or PSM cohort.

Conclusions: Distant LNM presents as a comparatively rare but grave condition with a substantial negative impact on prognosis in patients with DTC. Identified risk factors of distant LNM are older age, male, advanced T stage and N stage, bone metastasis, brain metastasis, and lung metastasis. Remarkably, the current RAI therapy does not appear to significantly improve the survival outcome of DTC patients with distant LNM.

背景:颈淋巴结转移(LNM)是分化型甲状腺癌(DTC)患者最常见的临床症状。然而,关于远处淋巴结转移的发生率、模式、治疗和预后尚无报道:方法:从监测、流行病学和最终结果(SEER)数据库中找出2016年至2020年间患有远处LNM的DTC患者。采用多变量模型和倾向得分匹配(PSM)来考虑协变量的影响。采用卡普兰-梅耶法评估总生存期(OS)和癌症特异性生存期(CSS)。建立了预测 DTC 患者远处 LNM 概率的提名图,并利用校准和接收者操作特征曲线(ROC)验证提名图的准确性:在接受筛查的 42,339 名 DTC 患者中,有 100 人(0.24%)出现远处 LNM。包括年龄、性别、T期、N期、骨转移、脑转移和肺转移在内的风险因素被纳入提名图,以预测远处LNM的概率。提名图的校准曲线接近理想对角线,ROC 曲线的曲线下面积(AUC)为 0.953。与非远端 LNM 相比,调整混杂因素后,远端 LNM 的预后更差(P 结论:远端 LNM 的预后更差:远处 LNM 比较罕见,但病情严重,对 DTC 患者的预后有很大的负面影响。已确定的远处淋巴结转移风险因素包括年龄较大、男性、T 期和 N 期晚期、骨转移、脑转移和肺转移。值得注意的是,目前的 RAI 治疗似乎并不能明显改善伴有远处 LNM 的 DTC 患者的生存预后。
{"title":"Distant lymph node metastasis in differentiated thyroid cancer: A population-based cohort study.","authors":"Ying Ding, Ruixin Zhou","doi":"10.1016/j.surge.2024.07.004","DOIUrl":"https://doi.org/10.1016/j.surge.2024.07.004","url":null,"abstract":"<p><strong>Background: </strong>Cervical lymph node metastasis (LNM) is the most common clinical event in patients with differentiated thyroid cancer (DTC). However, the incidence, pattern, treatment, and prognosis of distant LNM are yet to be reported.</p><p><strong>Methods: </strong>DTC patients with distant LNM were identified from the Surveillance, Epidemiology, and End Results (SEER) database between 2016 and 2020. Multivariate models and propensity score matching (PSM) were used to account for the effects of covariates. The Kaplan-Meier method was used to evaluate the overall survival (OS) and cancer-specific survival (CSS). A nomogram was established to predict the probability of distant LNM in DTC patients, with calibration and Receiver Operating Characteristic (ROC) curves utilized to validate the nomogram's accuracy.</p><p><strong>Results: </strong>Of the 42,339 DTC patients screened, 100 (0.24 %) patients presented with distant LNM. Risk factors including age, sex, T stage, N stage, bone metastasis, brain metastasis, and lung metastasis were included in the nomogram to predict the probability of distant LNM. The calibration curve of the nomogram was close to the ideal diagonal line and the area under the curve (AUC) of the ROC curve is 0.953. Distant LNM showed a worse prognosis after adjusting for confounders compared with non-distant LNM (P < 0.05). Remarkably, radioactive iodine (RAI) therapy did not improve the OS and CSS in DTC patients with distant LNM in the overall or PSM cohort.</p><p><strong>Conclusions: </strong>Distant LNM presents as a comparatively rare but grave condition with a substantial negative impact on prognosis in patients with DTC. Identified risk factors of distant LNM are older age, male, advanced T stage and N stage, bone metastasis, brain metastasis, and lung metastasis. Remarkably, the current RAI therapy does not appear to significantly improve the survival outcome of DTC patients with distant LNM.</p>","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141602037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pelvic floor imaging in women with hemorrhoidal disease: An anatomical feasibility study 痔疮妇女的盆底成像:解剖学可行性研究
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-07-09 DOI: 10.1016/j.surge.2024.06.006

Objective

To compare pelvic floor muscle and organ structures in women with and without hemorrhoidal disease (HD) using magnetic resonance imaging (MRI).

Material and methods

Pelvic MRI measurements and computer-based medical records of women diagnosed with HD between January 2018 and March 2021 were analyzed. Parameters including pubococcygeal distance, puborectal distance, posterior anorectal angle, obturator internus muscle area, presence of levator ani muscle defect, genital hiatus length, vaginal length, uterocervical angle, cervix-upper vagina angle, and cervix-middle vagina angle were evaluated. The control group consisted of women without HD, matched for age and body mass index.

Results

Puborectal hiatus distance was higher in the HD group (59.2 ​± ​8.7 ​mm vs. 55.5 ​± ​7.1 ​mm, p ​= ​0.03). Similarly, the distance to the M line was greater in the HD group (18.3 ​± ​4.8 ​mm vs. 16 ​± ​4.6 ​mm, p ​= ​0.04). Obturator internus muscle area was found to be lower in the HD group compared to the non-HD group (1721 ​± ​291.4 ​mm2 vs. 1897.5 ​± ​352.5 ​mm2, p ​= ​0.02). Additionally, the presence of unilateral levator ani muscle defect was higher in HD patients (p ​= ​0.03). There was a negative correlation between birthweight and obturator internus muscle area (r ​= ​−0.388, p ​= ​0.02), and a positive correlation with M line distance (r ​= ​0.344, p ​= ​0.04).

Conclusion

Levator ani muscle defects and obturator internus muscle area, indicators of pelvic floor dysfunction, are more common in patients with hemorrhoidal disease.

目的利用磁共振成像(MRI)比较有痔疮(HD)和无痔疮(HD)妇女的盆底肌肉和器官结构:对 2018 年 1 月至 2021 年 3 月期间确诊为 HD 的女性的盆腔 MRI 测量结果和计算机病历进行分析。评估参数包括耻骨尾骨间距、耻骨直肠间距、肛门直肠后角、闭孔肌面积、是否存在提肛肌缺损、生殖器裂隙长度、阴道长度、子宫颈角、子宫颈-阴道上角、子宫颈-阴道中角。对照组由年龄和体重指数相匹配的非 HD 女性组成:结果:HD 组的耻骨直肠间隙距离更大(59.2 ± 8.7 mm 对 55.5 ± 7.1 mm,P = 0.03)。同样,HD 组的 M 线距离也更大(18.3 ± 4.8 mm vs. 16 ± 4.6 mm,p = 0.04)。与非 HD 组相比,HD 组的闭孔肌面积更小(1721 ± 291.4 mm2 vs. 1897.5 ± 352.5 mm2,P = 0.02)。此外,HD 患者出现单侧提肛肌缺损的比例更高(p = 0.03)。出生体重与内收肌面积呈负相关(r = -0.388,p = 0.02),与 M 线距离呈正相关(r = 0.344,p = 0.04):结论:作为盆底功能障碍的指标,提肛肌缺损和闭孔肌面积在痔疮患者中更为常见。
{"title":"Pelvic floor imaging in women with hemorrhoidal disease: An anatomical feasibility study","authors":"","doi":"10.1016/j.surge.2024.06.006","DOIUrl":"10.1016/j.surge.2024.06.006","url":null,"abstract":"<div><h3>Objective</h3><p>To compare pelvic floor muscle and organ structures in women with and without hemorrhoidal disease (HD) using magnetic resonance imaging (MRI).</p></div><div><h3>Material and methods</h3><p><span><span>Pelvic MRI<span> measurements and computer-based medical records of women diagnosed with HD between January 2018 and March 2021 were analyzed. Parameters including pubococcygeal distance, puborectal distance, posterior anorectal angle, obturator internus muscle area, presence of </span></span>levator ani muscle defect, </span>genital hiatus<span> length, vaginal length, uterocervical angle, cervix-upper vagina angle, and cervix-middle vagina angle were evaluated. The control group consisted of women without HD, matched for age and body mass index.</span></p></div><div><h3>Results</h3><p>Puborectal hiatus distance was higher in the HD group (59.2 ​± ​8.7 ​mm vs. 55.5 ​± ​7.1 ​mm, p ​= ​0.03). Similarly, the distance to the M line was greater in the HD group (18.3 ​± ​4.8 ​mm vs. 16 ​± ​4.6 ​mm, p ​= ​0.04). Obturator internus muscle area was found to be lower in the HD group compared to the non-HD group (1721 ​± ​291.4 ​mm<sup>2</sup> vs. 1897.5 ​± ​352.5 ​mm<sup>2</sup>, p ​= ​0.02). Additionally, the presence of unilateral levator ani muscle defect was higher in HD patients (p ​= ​0.03). There was a negative correlation between birthweight and obturator internus muscle area (r ​= ​−0.388, p ​= ​0.02), and a positive correlation with M line distance (r ​= ​0.344, p ​= ​0.04).</p></div><div><h3>Conclusion</h3><p>Levator ani muscle defects and obturator internus muscle area, indicators of pelvic floor dysfunction, are more common in patients with hemorrhoidal disease.</p></div>","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":"22 5","pages":"Pages e181-e185"},"PeriodicalIF":2.3,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The positive effects of preoperative chlorhexidine rinse to reduce postoperative pneumonia after kidney transplantation surgery. 术前洗必泰冲洗对减少肾移植手术后肺炎的积极作用。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-07-08 DOI: 10.1016/j.surge.2024.07.001
Murat Ferhat Ferhatoglu, Osman Z Sahin, Taner Kivilcim, Alp Gurkan

Background: Postoperative pneumonia is one of the most observed hospital-acquired infections and increases the postoperative mortality rate. Further, it drives the healthcare systems under a severe financial burden. Preventing postoperative pneumonia is an incredibly challenging issue for clinicians. Since immunosuppression therapy, the patients who had kidney transplants are more vulnerable to postoperative infections. There is no data in the scientific literature focusing on the effects of preoperative oral care with chlorhexidine antiseptic solutions on postoperative pneumonia in kidney transplantation surgery cases. In the present research, we studied this topic.

Methods: A prospective, randomized clinical trial was conducted at our institution between August 2020 and August 2022. Group A: Received 0.12 % chlorhexidine oral rinse preoperatively; Group B: Not received 0.12 % chlorhexidine oral rinse preoperatively. We analyzed the differences between the two trial groups using a chi-square or t-test. The Mann-Whitney U test was used for the categorical data.

Results: Nine patients (17.6 %) were diagnosed with postoperative pneumonia in Group A and fourteen (25.9 %) in Group B (p < 0.05). Hospitalization time of Group B was prolonged (p < 0.05). In multivariate analysis, significant risk factors associated with postoperative pneumonia were advanced age, diabetes mellitus, smoking, delayed graft function and not gargling with 0.12 % chlorhexidine (p < 0.05).

Conclusions: To reduce postoperative pneumonia risk in patients undergoing kidney transplantation surgery, an oral health protocol including 0.12 % chlorhexidine mouth rinse seems beneficial.

背景:术后肺炎是最常见的医院获得性感染之一,会增加术后死亡率。此外,它还使医疗系统承受着沉重的经济负担。对于临床医生来说,预防术后肺炎是一个极具挑战性的问题。由于接受了免疫抑制治疗,肾移植患者更容易发生术后感染。目前还没有科学文献关注术前使用洗必泰消毒液进行口腔护理对肾移植手术病例术后肺炎的影响。在本研究中,我们对这一课题进行了研究:2020年8月至2022年8月在我院进行了一项前瞻性随机临床试验。A组A组:术前接受0.12%洗必泰口腔冲洗;B组:术前未接受0.12%洗必泰口腔冲洗。我们使用卡方检验或 t 检验分析了两个试验组之间的差异。对分类数据采用曼-惠特尼 U 检验:结果:A 组有 9 名患者(17.6%)被诊断为术后肺炎,B 组有 14 名患者(25.9%)被诊断为术后肺炎:为了降低肾移植手术患者术后肺炎的风险,包括 0.12 % 洗必泰漱口水在内的口腔保健方案似乎是有益的。
{"title":"The positive effects of preoperative chlorhexidine rinse to reduce postoperative pneumonia after kidney transplantation surgery.","authors":"Murat Ferhat Ferhatoglu, Osman Z Sahin, Taner Kivilcim, Alp Gurkan","doi":"10.1016/j.surge.2024.07.001","DOIUrl":"https://doi.org/10.1016/j.surge.2024.07.001","url":null,"abstract":"<p><strong>Background: </strong>Postoperative pneumonia is one of the most observed hospital-acquired infections and increases the postoperative mortality rate. Further, it drives the healthcare systems under a severe financial burden. Preventing postoperative pneumonia is an incredibly challenging issue for clinicians. Since immunosuppression therapy, the patients who had kidney transplants are more vulnerable to postoperative infections. There is no data in the scientific literature focusing on the effects of preoperative oral care with chlorhexidine antiseptic solutions on postoperative pneumonia in kidney transplantation surgery cases. In the present research, we studied this topic.</p><p><strong>Methods: </strong>A prospective, randomized clinical trial was conducted at our institution between August 2020 and August 2022. Group A: Received 0.12 % chlorhexidine oral rinse preoperatively; Group B: Not received 0.12 % chlorhexidine oral rinse preoperatively. We analyzed the differences between the two trial groups using a chi-square or t-test. The Mann-Whitney U test was used for the categorical data.</p><p><strong>Results: </strong>Nine patients (17.6 %) were diagnosed with postoperative pneumonia in Group A and fourteen (25.9 %) in Group B (p < 0.05). Hospitalization time of Group B was prolonged (p < 0.05). In multivariate analysis, significant risk factors associated with postoperative pneumonia were advanced age, diabetes mellitus, smoking, delayed graft function and not gargling with 0.12 % chlorhexidine (p < 0.05).</p><p><strong>Conclusions: </strong>To reduce postoperative pneumonia risk in patients undergoing kidney transplantation surgery, an oral health protocol including 0.12 % chlorhexidine mouth rinse seems beneficial.</p>","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141564947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Climate change and environmental sustainability in otolaryngology: A state-of-the-art review 耳鼻咽喉科的气候变化和环境可持续性:最新综述。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-07-06 DOI: 10.1016/j.surge.2024.06.007

Background

Climate change has been identified by the World Health Organization (WHO) as the greatest existing threat to human health. Given the direct exposure of the upper aerodigestive system to pollutants, patients in otolaryngology are at high risk for increased disease burden in the setting of climate change and worsening air quality. Given this and the environmental impact of surgical care, it is essential for surgeons to understand their role in addressing climate health through quality-driven clinical initiatives, education, advocacy, and research.

Methods

A state-of-the-art review was performed of the existing literature on the otolaryngologic health impacts of climate change and environmental sustainability efforts in surgery with specific attention to studies in otolaryngology – head and neck surgery.

Findings

Climate variables including heat and air pollution are associated with increased incidence of allergic rhinitis, chronic rhinosinusitis and head and neck cancer. A number of studies have shown that sustainability initiatives in otolaryngology are safe and provide direct cost benefit.

Conclusion

Surgeons have the opportunity to lead on climate health and sustainability to address the public health burden of climate change.

背景:气候变化已被世界卫生组织(WHO)确定为目前对人类健康的最大威胁。由于上消化道系统直接暴露于污染物中,耳鼻喉科患者在气候变化和空气质量恶化的环境中面临疾病负担加重的高风险。有鉴于此以及外科护理对环境的影响,外科医生必须了解他们在通过以质量为导向的临床举措、教育、宣传和研究来应对气候健康方面所扮演的角色:方法:我们对有关气候变化对耳鼻咽喉科健康的影响以及外科手术中环境可持续性努力的现有文献进行了最新综述,并特别关注了耳鼻咽喉科--头颈外科的研究:研究结果:包括高温和空气污染在内的气候变量与过敏性鼻炎、慢性鼻炎和头颈部癌症发病率的增加有关。许多研究表明,耳鼻喉科的可持续发展措施是安全的,并能带来直接的成本效益:外科医生有机会在气候健康和可持续发展方面发挥领导作用,以应对气候变化给公共健康带来的负担。
{"title":"Climate change and environmental sustainability in otolaryngology: A state-of-the-art review","authors":"","doi":"10.1016/j.surge.2024.06.007","DOIUrl":"10.1016/j.surge.2024.06.007","url":null,"abstract":"<div><h3>Background</h3><p><span><span>Climate change has been identified by the World Health Organization (WHO) as the greatest existing threat to human health. Given the direct exposure of the upper aerodigestive system to pollutants, patients in </span>otolaryngology are at high risk for increased </span>disease burden in the setting of climate change and worsening air quality. Given this and the environmental impact of surgical care, it is essential for surgeons to understand their role in addressing climate health through quality-driven clinical initiatives, education, advocacy, and research.</p></div><div><h3>Methods</h3><p>A state-of-the-art review was performed of the existing literature on the otolaryngologic health impacts of climate change and environmental sustainability efforts in surgery with specific attention to studies in otolaryngology – head and neck surgery.</p></div><div><h3>Findings</h3><p>Climate variables including heat and air pollution are associated with increased incidence of allergic rhinitis, chronic rhinosinusitis<span> and head and neck cancer. A number of studies have shown that sustainability initiatives in otolaryngology are safe and provide direct cost benefit.</span></p></div><div><h3>Conclusion</h3><p>Surgeons have the opportunity to lead on climate health and sustainability to address the public health burden of climate change.</p></div>","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":"22 5","pages":"Pages 270-275"},"PeriodicalIF":2.3,"publicationDate":"2024-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141555731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial penile cancer – Super-regional centres 编辑阴茎癌 - 超级区域中心。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-07-05 DOI: 10.1016/j.surge.2024.06.003
{"title":"Editorial penile cancer – Super-regional centres","authors":"","doi":"10.1016/j.surge.2024.06.003","DOIUrl":"10.1016/j.surge.2024.06.003","url":null,"abstract":"","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":"22 5","pages":"Pages 290-291"},"PeriodicalIF":2.3,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141545450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The surgical outpatient clinic and the environment 外科门诊和环境。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-07-03 DOI: 10.1016/j.surge.2024.06.005

Rising global temperatures will have a radical impact on the environment where global warming is associated with weather extremes such as thunderstorms and droughts which can affect the regional ecosystems. The healthcare sector is a major emitter of greenhouse gasses. Within healthcare, the outpatient clinic is responsible for a considerable sum of emissions. These can be organized under scopes 1, 2 and 3 as described in the Greenhouse Gas Protocol where scope 1 accounts for direct emissions from healthcare facilities, scope 2 is emissions from purchased electricity and scope 3 is indirect emissions including procurement and waste.

Emissions and mitigation strategies from the surgical outpatient clinic are outlined under each scope of the Greenhouse Gas Protocol. These include using insulation materials, renovating or building new facilities, incorporating renewable energy sources and utilizing more efficient appliances.

Telehealth and virtual clinics have been shown to be an effective method of delivering care while avoiding the combustion of fossil fuels to facilitate patient transport. In addition, virtual set-ups are cost effective and have not been proven to compromise patient safety when implemented correctly.

全球气温升高将对环境产生巨大影响,因为全球变暖会导致雷暴和干旱等极端天气,从而影响区域生态系统。医疗保健行业是温室气体的主要排放者。在医疗保健领域,门诊部的排放量相当大。根据《温室气体议定书》的描述,这些排放可分为范围 1、2 和 3,其中范围 1 代表医疗设施的直接排放,范围 2 代表外购电力的排放,范围 3 代表包括采购和废物在内的间接排放。在《温室气体议定书》的每个范围下都概述了外科门诊的排放量和减排策略。这些策略包括使用隔热材料、翻新或新建设施、采用可再生能源以及使用更高效的电器。远程医疗和虚拟诊所已被证明是提供医疗服务的有效方法,同时可避免燃烧化石燃料以方便运送病人。此外,虚拟设置还具有成本效益,而且经证实,如果正确实施,不会影响病人的安全。
{"title":"The surgical outpatient clinic and the environment","authors":"","doi":"10.1016/j.surge.2024.06.005","DOIUrl":"10.1016/j.surge.2024.06.005","url":null,"abstract":"<div><p><span>Rising global temperatures will have a radical impact on the environment where global warming is associated with weather extremes such as </span>thunderstorms<span> and droughts which can affect the regional ecosystems. The healthcare sector is a major emitter of greenhouse gasses. Within healthcare, the outpatient clinic is responsible for a considerable sum of emissions. These can be organized under scopes 1, 2 and 3 as described in the Greenhouse Gas Protocol where scope 1 accounts for direct emissions from healthcare facilities, scope 2 is emissions from purchased electricity and scope 3 is indirect emissions including procurement and waste.</span></p><p>Emissions and mitigation strategies from the surgical outpatient clinic are outlined under each scope of the Greenhouse Gas Protocol. These include using insulation materials, renovating or building new facilities, incorporating renewable energy sources and utilizing more efficient appliances.</p><p><span>Telehealth<span> and virtual clinics have been shown to be an effective method of delivering care while avoiding the combustion of fossil fuels to facilitate patient transport. In addition, virtual set-ups are cost effective and have not been proven to compromise </span></span>patient safety when implemented correctly.</p></div>","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":"22 5","pages":"Pages 267-269"},"PeriodicalIF":2.3,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141535724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1